Caenorhabditis elegans

16 known processes

clp-1 (CELE_C06G4.2)

Protein CLP-1

clp-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.253
Mouse
post embryonic development GO:0009791 2152 0.243
cellular macromolecule biosynthetic process GO:0034645 247 0.204
Mouse
embryo development GO:0009790 3052 0.203
Mouse
organ development GO:0048513 1102 0.189
Mouse
signal transduction GO:0007165 317 0.145
Mouse
oviposition GO:0018991 364 0.143
single organism reproductive process GO:0044702 1196 0.143
behavior GO:0007610 527 0.142
developmental process involved in reproduction GO:0003006 1165 0.139
Worm
regulation of growth GO:0040008 409 0.136
Mouse
synaptic transmission GO:0007268 106 0.135
developmental growth GO:0048589 412 0.130
Mouse
multicellular organismal reproductive process GO:0048609 815 0.124
cellular biosynthetic process GO:0044249 315 0.116
Mouse
pronuclear migration GO:0035046 51 0.111
aging GO:0007568 812 0.110
positive regulation of multicellular organismal process GO:0051240 417 0.110
gonad development GO:0008406 840 0.107
gene expression GO:0010467 412 0.106
Mouse Worm
growth GO:0040007 562 0.104
Mouse
locomotion GO:0040011 1634 0.104
determination of adult lifespan GO:0008340 812 0.104
female gamete generation GO:0007292 254 0.097
vulval development GO:0040025 333 0.093
development of primary sexual characteristics GO:0045137 840 0.091
regulation of developmental growth GO:0048638 389 0.090
Mouse
regulation of multicellular organism growth GO:0040014 373 0.088
biosynthetic process GO:0009058 323 0.083
Mouse
gamete generation GO:0007276 461 0.081
regulation of gene expression GO:0010468 366 0.080
Mouse
multi multicellular organism process GO:0044706 390 0.078
embryonic morphogenesis GO:0048598 152 0.078
catabolic process GO:0009056 318 0.076
Mouse
fertilization GO:0009566 63 0.076
protein metabolic process GO:0019538 422 0.076
Mouse Worm
multi organism reproductive process GO:0044703 867 0.074
multi organism reproductive behavior GO:0044705 387 0.072
apoptotic process GO:0006915 478 0.072
Mouse
ion transmembrane transport GO:0034220 91 0.072
macromolecule modification GO:0043412 218 0.070
system process GO:0003008 136 0.070
sex differentiation GO:0007548 909 0.070
positive regulation of multicellular organism growth GO:0040018 352 0.068
transmembrane transport GO:0055085 110 0.068
multi organism behavior GO:0051705 389 0.068
endocytosis GO:0006897 819 0.066
single organism organelle organization GO:1902589 501 0.066
Mouse
multicellular organism reproduction GO:0032504 819 0.065
multicellular organism growth GO:0035264 385 0.065
reproductive behavior GO:0019098 387 0.065
maintenance of location GO:0051235 580 0.065
carbohydrate derivative metabolic process GO:1901135 141 0.064
neuron development GO:0048666 199 0.063
multicellular organismal reproductive behavior GO:0033057 384 0.061
regulation of cell communication GO:0010646 176 0.061
Mouse
muscle tissue development GO:0060537 1 0.060
Mouse
regulation of biological quality GO:0065008 741 0.060
Mouse
regulation of multicellular organismal process GO:0051239 726 0.060
Mouse
small gtpase mediated signal transduction GO:0007264 32 0.060
reproductive structure development GO:0048608 850 0.060
death GO:0016265 547 0.059
head development GO:0060322 1 0.059
regulation of developmental process GO:0050793 684 0.058
Mouse
cellular component assembly GO:0022607 293 0.058
Mouse
cell death GO:0008219 547 0.057
spicule insertion GO:0034609 2 0.057
receptor mediated endocytosis GO:0006898 715 0.054
lipid storage GO:0019915 565 0.054
nervous system development GO:0007399 253 0.054
body morphogenesis GO:0010171 620 0.053
single organism localization GO:1902578 518 0.053
Mouse
macromolecule biosynthetic process GO:0009059 250 0.052
Mouse
reproductive system development GO:0061458 850 0.052
cellular response to organic substance GO:0071310 119 0.052
Mouse
establishment of localization GO:0051234 1171 0.052
Mouse
organic substance biosynthetic process GO:1901576 323 0.051
Mouse
positive regulation of developmental process GO:0051094 408 0.050
Mouse
intracellular signal transduction GO:0035556 96 0.050
Mouse
cell development GO:0048468 696 0.050
Mouse
multicellular organismal aging GO:0010259 812 0.050
single organism signaling GO:0044700 401 0.049
Mouse
response to chemical GO:0042221 356 0.049
Mouse
macromolecule localization GO:0033036 771 0.048
Mouse
microtubule based process GO:0007017 182 0.048
nucleobase containing compound biosynthetic process GO:0034654 184 0.048
Mouse
aromatic compound biosynthetic process GO:0019438 192 0.047
Mouse
regulation of synaptic transmission GO:0050804 34 0.047
negative regulation of cytosolic calcium ion concentration GO:0051481 1 0.047
lipid localization GO:0010876 573 0.047
signaling GO:0023052 401 0.046
Mouse
regulation of metabolic process GO:0019222 478 0.046
Mouse
positive regulation of growth GO:0045927 369 0.046
Mouse
hermaphrodite genitalia development GO:0040035 734 0.046
regulation of meiotic cell cycle GO:0051445 136 0.045
regulation of signaling GO:0023051 172 0.045
Mouse
nuclear migration GO:0007097 54 0.045
neuromuscular junction development GO:0007528 2 0.045
post embryonic organ development GO:0048569 336 0.045
programmed cell death GO:0012501 500 0.044
Mouse
single organism transport GO:0044765 447 0.044
Mouse
cellular protein metabolic process GO:0044267 279 0.044
Mouse
organelle organization GO:0006996 783 0.043
Mouse
regulation of macromolecule metabolic process GO:0060255 421 0.043
Mouse
organelle assembly GO:0070925 214 0.042
Mouse
negative regulation of multicellular organismal process GO:0051241 236 0.042
cellular catabolic process GO:0044248 199 0.042
Mouse
negative regulation of biological process GO:0048519 567 0.042
Mouse
nucleic acid metabolic process GO:0090304 299 0.042
Mouse
feeding behavior GO:0007631 70 0.041
apical junction assembly GO:0043297 1 0.041
protein modification process GO:0036211 207 0.041
negative regulation of metabolic process GO:0009892 240 0.041
Mouse
regulation of cell cycle GO:0051726 194 0.040
germ cell development GO:0007281 351 0.040
sexual reproduction GO:0019953 546 0.040
embryonic body morphogenesis GO:0010172 49 0.040
skeletal muscle organ development GO:0060538 3 0.040
Mouse
positive regulation of developmental growth GO:0048639 354 0.040
Mouse
regulation of multicellular organismal development GO:2000026 317 0.039
Mouse
single fertilization GO:0007338 61 0.039
oogenesis GO:0048477 229 0.038
regulation of organelle organization GO:0033043 164 0.038
transport GO:0006810 1093 0.038
Mouse
small molecule metabolic process GO:0044281 186 0.037
cation transmembrane transport GO:0098655 59 0.036
regulation of small gtpase mediated signal transduction GO:0051056 41 0.036
protein catabolic process GO:0030163 162 0.035
organic acid metabolic process GO:0006082 47 0.035
regulation of signal transduction GO:0009966 135 0.034
Mouse
response to external stimulus GO:0009605 289 0.034
Mouse
cell junction organization GO:0034330 18 0.034
regulation of nematode larval development GO:0061062 260 0.034
regulation of lipid biosynthetic process GO:0046890 1 0.034
positive regulation of cellular biosynthetic process GO:0031328 109 0.033
Mouse
regulation of response to stimulus GO:0048583 243 0.033
Mouse
regulation of intracellular signal transduction GO:1902531 77 0.033
Mouse
vesicle mediated transport GO:0016192 852 0.033
negative regulation of macromolecule metabolic process GO:0010605 229 0.033
Mouse
cellular component morphogenesis GO:0032989 318 0.033
Mouse
organ morphogenesis GO:0009887 67 0.032
Mouse
cellular protein modification process GO:0006464 207 0.032
organic substance catabolic process GO:1901575 294 0.032
Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.032
Mouse
regulation of locomotion GO:0040012 161 0.032
ras protein signal transduction GO:0007265 31 0.031
metal ion transport GO:0030001 49 0.031
Mouse
cellular component movement GO:0006928 388 0.031
regulation of rna metabolic process GO:0051252 173 0.031
Mouse
macromolecular complex subunit organization GO:0043933 320 0.031
Mouse
muscle structure development GO:0061061 191 0.031
Mouse
cell division GO:0051301 262 0.030
epithelial tube morphogenesis GO:0060562 1 0.030
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.030
Mouse
response to wounding GO:0009611 4 0.030
Mouse
dauer larval development GO:0040024 92 0.029
establishment of localization in cell GO:0051649 318 0.029
Mouse
protein complex biogenesis GO:0070271 186 0.028
Mouse
cytoskeleton organization GO:0007010 339 0.028
Mouse
generation of neurons GO:0048699 235 0.028
cellular component assembly involved in morphogenesis GO:0010927 183 0.028
Mouse
heterocycle biosynthetic process GO:0018130 187 0.027
Mouse
genitalia development GO:0048806 741 0.027
regulation of primary metabolic process GO:0080090 292 0.027
Mouse
regulation of cytoplasmic transport GO:1903649 3 0.027
Mouse
cgmp metabolic process GO:0046068 2 0.027
anatomical structure formation involved in morphogenesis GO:0048646 250 0.027
Mouse
sodium ion transport GO:0006814 10 0.026
ion transport GO:0006811 113 0.026
Mouse
negative regulation of nematode larval development GO:0061064 208 0.026
cation transport GO:0006812 78 0.026
Mouse
oocyte differentiation GO:0009994 45 0.026
cellular response to stress GO:0033554 162 0.026
Mouse
cell cycle GO:0007049 526 0.025
Mouse
regulation of cellular biosynthetic process GO:0031326 189 0.025
Mouse
actomyosin structure organization GO:0031032 154 0.025
Mouse
cuticle development GO:0042335 100 0.025
oxoacid metabolic process GO:0043436 47 0.025
cell surface receptor signaling pathway GO:0007166 149 0.025
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.025
neurological system process GO:0050877 53 0.024
macromolecule catabolic process GO:0009057 202 0.024
Mouse
regulation of feeding behavior GO:0060259 38 0.024
g protein coupled receptor signaling pathway GO:0007186 46 0.023
cognition GO:0050890 27 0.023
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.023
response to endogenous stimulus GO:0009719 33 0.023
Mouse
cellular localization GO:0051641 360 0.023
Mouse
organic cyclic compound biosynthetic process GO:1901362 195 0.023
Mouse
negative regulation of neurogenesis GO:0050768 4 0.023
phosphorus metabolic process GO:0006793 232 0.023
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.023
Mouse
pharyngeal pumping GO:0043050 58 0.022
negative regulation of developmental process GO:0051093 227 0.022
nematode male tail tip morphogenesis GO:0045138 77 0.022
synaptic growth at neuromuscular junction GO:0051124 1 0.022
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.022
Mouse
cell cell signaling GO:0007267 118 0.022
protein modification by small protein conjugation or removal GO:0070647 40 0.022
actin cytoskeleton organization GO:0030036 184 0.022
Mouse
tissue development GO:0009888 112 0.022
Mouse
tube morphogenesis GO:0035239 79 0.022
regulation of nucleic acid templated transcription GO:1903506 165 0.021
Mouse
muscle cell differentiation GO:0042692 171 0.021
Mouse
negative regulation of cell communication GO:0010648 61 0.021
anion transport GO:0006820 30 0.021
regulation of cellular component organization GO:0051128 248 0.021
eating behavior GO:0042755 59 0.020
regulation of anatomical structure size GO:0090066 46 0.020
localization of cell GO:0051674 313 0.020
purine ribonucleoside monophosphate catabolic process GO:0009169 28 0.020
establishment of nucleus localization GO:0040023 55 0.020
homeostatic process GO:0042592 51 0.020
Mouse
neurogenesis GO:0022008 236 0.020
organelle localization GO:0051640 127 0.020
meiotic nuclear division GO:0007126 300 0.020
actin filament based process GO:0030029 191 0.020
Mouse
protein autoprocessing GO:0016540 2 0.019
Worm
muscle contraction GO:0006936 43 0.019
nucleobase containing compound metabolic process GO:0006139 406 0.019
Mouse
carboxylic acid metabolic process GO:0019752 34 0.019
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.019
Mouse
positive regulation of cellular metabolic process GO:0031325 178 0.019
Mouse
response to other organism GO:0051707 101 0.019
nucleus localization GO:0051647 55 0.019
cellular response to chemical stimulus GO:0070887 129 0.019
Mouse
cytosolic calcium ion homeostasis GO:0051480 2 0.019
Mouse
meiotic cell cycle GO:0051321 335 0.019
cell migration GO:0016477 306 0.019
regulation of nucleocytoplasmic transport GO:0046822 3 0.018
organonitrogen compound metabolic process GO:1901564 151 0.018
molting cycle GO:0042303 281 0.018
regulation of cellular metabolic process GO:0031323 305 0.018
Mouse
protein complex subunit organization GO:0071822 280 0.018
Mouse
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
cell motility GO:0048870 313 0.018
regulation of macromolecule biosynthetic process GO:0010556 189 0.018
Mouse
regulation of response to wounding GO:1903034 1 0.018
Mouse
single organism catabolic process GO:0044712 129 0.018
regulation of post embryonic development GO:0048580 260 0.018
mating behavior GO:0007617 32 0.018
cellular component biogenesis GO:0044085 297 0.017
Mouse
regulation of reproductive process GO:2000241 66 0.017
cellular ketone metabolic process GO:0042180 14 0.017
bmp signaling pathway GO:0030509 3 0.017
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.017
Mouse
secretion by cell GO:0032940 138 0.017
negative regulation of signaling GO:0023057 61 0.017
cellular nitrogen compound biosynthetic process GO:0044271 192 0.017
Mouse
regulation of cellular ketone metabolic process GO:0010565 3 0.017
apoptotic cell clearance GO:0043277 111 0.017
tube development GO:0035295 126 0.017
negative regulation of vulval development GO:0040027 206 0.017
phosphate containing compound metabolic process GO:0006796 232 0.016
sensory organ morphogenesis GO:0090596 2 0.016
regulation of biosynthetic process GO:0009889 189 0.016
Mouse
response to oxygen containing compound GO:1901700 44 0.016
Mouse
adult behavior GO:0030534 3 0.016
transcription from rna polymerase ii promoter GO:0006366 149 0.016
hermaphrodite germ line sex determination GO:0040021 48 0.016
transcription dna templated GO:0006351 168 0.016
Mouse
regulation of synapse assembly GO:0051963 2 0.016
regulation of protein targeting GO:1903533 3 0.015
ribonucleoside triphosphate catabolic process GO:0009203 72 0.015
cell growth GO:0016049 44 0.015
organophosphate metabolic process GO:0019637 125 0.015
cellular response to nitrogen compound GO:1901699 24 0.015
Mouse
potassium ion transmembrane transport GO:0071805 20 0.015
negative regulation of post embryonic development GO:0048581 208 0.015
mitotic nuclear division GO:0007067 89 0.015
monovalent inorganic cation transport GO:0015672 33 0.015
regulation of epithelial cell proliferation GO:0050678 1 0.015
rna biosynthetic process GO:0032774 169 0.015
Mouse
cell cell junction assembly GO:0007043 2 0.015
phosphorylation GO:0016310 116 0.015
regulation of organ morphogenesis GO:2000027 4 0.015
membrane invagination GO:0010324 98 0.015
single organism intracellular transport GO:1902582 70 0.015
Mouse
cell proliferation GO:0008283 116 0.015
positive regulation of metabolic process GO:0009893 187 0.015
Mouse
regulation of behavior GO:0050795 97 0.015
regulation of striated muscle contraction GO:0006942 4 0.014
regulation of phosphorus metabolic process GO:0051174 81 0.014
phagocytosis GO:0006909 115 0.014
neuromuscular process GO:0050905 1 0.014
regulation of g protein coupled receptor protein signaling pathway GO:0008277 4 0.014
organelle fission GO:0048285 363 0.014
secretion GO:0046903 147 0.014
cell morphogenesis GO:0000902 163 0.014
protein oligomerization GO:0051259 4 0.014
positive regulation of rna biosynthetic process GO:1902680 102 0.014
Mouse
generation of precursor metabolites and energy GO:0006091 18 0.014
spindle organization GO:0007051 92 0.014
regulation of cell division GO:0051302 142 0.014
regulation of cellular amine metabolic process GO:0033238 0 0.014
positive regulation of neuron projection development GO:0010976 4 0.014
regulation of vulval development GO:0040028 248 0.013
response to external biotic stimulus GO:0043207 101 0.013
chromosome organization GO:0051276 104 0.013
collagen and cuticulin based cuticle development GO:0040002 99 0.013
cellular amine metabolic process GO:0044106 15 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.013
engulfment of apoptotic cell GO:0043652 94 0.013
canonical wnt signaling pathway GO:0060070 3 0.013
muscle cell development GO:0055001 158 0.013
Mouse
protein complex assembly GO:0006461 186 0.013
Mouse
phagocytosis engulfment GO:0006911 98 0.013
response to abiotic stimulus GO:0009628 152 0.013
Mouse
negative regulation of gene expression GO:0010629 217 0.013
Mouse
macromolecular complex assembly GO:0065003 193 0.013
Mouse
positive regulation of calcium ion transport GO:0051928 1 0.013
Mouse
response to organic substance GO:0010033 131 0.013
Mouse
cellular nitrogen compound catabolic process GO:0044270 119 0.013
regulation of transcription dna templated GO:0006355 164 0.013
Mouse
single organism behavior GO:0044708 83 0.013
dopamine receptor signaling pathway GO:0007212 11 0.012
ribonucleoprotein complex assembly GO:0022618 4 0.012
regeneration GO:0031099 4 0.012
Mouse
organic substance transport GO:0071702 113 0.012
cell fate commitment GO:0045165 139 0.012
pigmentation GO:0043473 2 0.012
peptide hormone secretion GO:0030072 2 0.012
ribonucleoside catabolic process GO:0042454 77 0.012
negative regulation of transcription dna templated GO:0045892 53 0.012
Mouse
anion transmembrane transport GO:0098656 21 0.012
regulation of bmp signaling pathway GO:0030510 3 0.012
positive regulation of gene expression GO:0010628 112 0.012
Mouse
response to biotic stimulus GO:0009607 101 0.012
amine metabolic process GO:0009308 15 0.012
cell type specific apoptotic process GO:0097285 4 0.012
inorganic cation transmembrane transport GO:0098662 46 0.012
protein phosphorylation GO:0006468 85 0.011
nucleoside phosphate metabolic process GO:0006753 108 0.011
rna metabolic process GO:0016070 228 0.011
Mouse
positive regulation of protein transport GO:0051222 4 0.011
regulation of cell cycle process GO:0010564 145 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.011
Mouse
regulation of transferase activity GO:0051338 31 0.011
myosin filament assembly GO:0031034 138 0.011
intraspecies interaction between organisms GO:0051703 3 0.011
cell cycle process GO:0022402 482 0.011
Mouse
sex determination GO:0007530 60 0.011
Worm
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.011
nucleoside catabolic process GO:0009164 78 0.011
regulation of mitotic cell cycle GO:0007346 76 0.011
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.011
negative regulation of signal transduction GO:0009968 60 0.011
ribonucleotide catabolic process GO:0009261 75 0.011
myosin filament organization GO:0031033 138 0.011
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 2 0.011
Mouse
regulation of cellular protein metabolic process GO:0032268 75 0.011
Mouse
adult locomotory behavior GO:0008344 1 0.011
purine nucleotide metabolic process GO:0006163 95 0.011
regulation of rna biosynthetic process GO:2001141 165 0.011
Mouse
ribonucleotide metabolic process GO:0009259 99 0.011
nucleobase containing compound catabolic process GO:0034655 114 0.011
regulation of neurogenesis GO:0050767 40 0.011
response to nitrogen compound GO:1901698 25 0.011
Mouse
neuron projection morphogenesis GO:0048812 114 0.011
regulation of ion transport GO:0043269 39 0.011
Mouse
ribose phosphate metabolic process GO:0019693 99 0.011
regulation of cellular component biogenesis GO:0044087 26 0.011
negative regulation of response to stimulus GO:0048585 73 0.010
spermatogenesis GO:0007283 41 0.010
establishment of organelle localization GO:0051656 123 0.010
aromatic compound catabolic process GO:0019439 116 0.010
regulation of programmed cell death GO:0043067 50 0.010
Mouse
intracellular transport GO:0046907 77 0.010
Mouse
striated muscle myosin thick filament assembly GO:0071688 138 0.010
regulation of canonical wnt signaling pathway GO:0060828 1 0.010
negative regulation of cellular process GO:0048523 239 0.010
Mouse
cellular response to light stimulus GO:0071482 1 0.010
neuron differentiation GO:0030182 217 0.010
hormone transport GO:0009914 2 0.010
single organism biosynthetic process GO:0044711 91 0.010
establishment of mitotic spindle orientation GO:0000132 28 0.010
gene silencing by rna GO:0031047 143 0.010

clp-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.060
disease of metabolism DOID:0014667 0 0.037
nervous system disease DOID:863 0 0.019
inherited metabolic disorder DOID:655 0 0.018
musculoskeletal system disease DOID:17 0 0.018
heart disease DOID:114 0 0.010
cardiovascular system disease DOID:1287 0 0.010