Caenorhabditis elegans

0 known processes

sir-2.4 (CELE_C06A5.11)

Protein SIR-2.4

sir-2.4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
multi organism reproductive process GO:0044703 867 0.506
multicellular organism reproduction GO:0032504 819 0.456
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.269
establishment of localization GO:0051234 1171 0.241
gamete generation GO:0007276 461 0.228
post embryonic development GO:0009791 2152 0.214
regulation of metabolic process GO:0019222 478 0.211
embryo development GO:0009790 3052 0.207
locomotion GO:0040011 1634 0.206
developmental process involved in reproduction GO:0003006 1165 0.202
embryo development ending in birth or egg hatching GO:0009792 2992 0.169
organelle organization GO:0006996 783 0.160
molting cycle GO:0042303 281 0.156
cell development GO:0048468 696 0.155
regulation of gene expression GO:0010468 366 0.146
multicellular organismal aging GO:0010259 812 0.140
regulation of nematode larval development GO:0061062 260 0.140
programmed cell death GO:0012501 500 0.140
germ cell development GO:0007281 351 0.135
transport GO:0006810 1093 0.133
determination of adult lifespan GO:0008340 812 0.128
multicellular organismal reproductive process GO:0048609 815 0.121
meiotic nuclear division GO:0007126 300 0.120
meiotic cell cycle GO:0051321 335 0.120
positive regulation of cellular process GO:0048522 332 0.119
gene expression GO:0010467 412 0.119
macromolecule localization GO:0033036 771 0.119
sexual reproduction GO:0019953 546 0.118
organ development GO:0048513 1102 0.116
regulation of biological quality GO:0065008 741 0.111
regulation of multicellular organismal development GO:2000026 317 0.111
behavior GO:0007610 527 0.111
nucleobase containing compound metabolic process GO:0006139 406 0.110
cell death GO:0008219 547 0.107
growth GO:0040007 562 0.103
aging GO:0007568 812 0.095
single organism reproductive process GO:0044702 1196 0.094
cellular component biogenesis GO:0044085 297 0.094
vulval development GO:0040025 333 0.089
oviposition GO:0018991 364 0.085
regulation of multicellular organismal process GO:0051239 726 0.082
regulation of macromolecule metabolic process GO:0060255 421 0.080
multicellular organismal reproductive behavior GO:0033057 384 0.079
reproductive structure development GO:0048608 850 0.079
macromolecule biosynthetic process GO:0009059 250 0.078
maintenance of location GO:0051235 580 0.078
multi organism behavior GO:0051705 389 0.078
death GO:0016265 547 0.077
body morphogenesis GO:0010171 620 0.074
lipid storage GO:0019915 565 0.069
protein metabolic process GO:0019538 422 0.069
lipid localization GO:0010876 573 0.067
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.066
regulation of cell cycle GO:0051726 194 0.063
single organism signaling GO:0044700 401 0.063
single organism localization GO:1902578 518 0.062
regulation of post embryonic development GO:0048580 260 0.057
female gamete generation GO:0007292 254 0.056
multi multicellular organism process GO:0044706 390 0.055
negative regulation of biological process GO:0048519 567 0.054
regulation of developmental growth GO:0048638 389 0.052
post embryonic organ development GO:0048569 336 0.051
cell motility GO:0048870 313 0.051
reproductive behavior GO:0019098 387 0.050
regulation of nitrogen compound metabolic process GO:0051171 222 0.050
gonad development GO:0008406 840 0.048
cellular component movement GO:0006928 388 0.048
development of primary sexual characteristics GO:0045137 840 0.047
negative regulation of multicellular organismal process GO:0051241 236 0.047
apoptotic process GO:0006915 478 0.046
nucleic acid metabolic process GO:0090304 299 0.045
cell cycle process GO:0022402 482 0.045
establishment of localization in cell GO:0051649 318 0.045
multi organism reproductive behavior GO:0044705 387 0.043
organelle fission GO:0048285 363 0.043
organic substance biosynthetic process GO:1901576 323 0.043
negative regulation of cellular process GO:0048523 239 0.041
vesicle mediated transport GO:0016192 852 0.041
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.041
positive regulation of multicellular organismal process GO:0051240 417 0.039
regulation of primary metabolic process GO:0080090 292 0.038
regulation of developmental process GO:0050793 684 0.038
cellular component assembly GO:0022607 293 0.038
cell type specific apoptotic process GO:0097285 4 0.037
negative regulation of metabolic process GO:0009892 240 0.037
developmental growth GO:0048589 412 0.036
cellular localization GO:0051641 360 0.035
single organism transport GO:0044765 447 0.035
chromosome segregation GO:0007059 180 0.033
cell migration GO:0016477 306 0.033
hermaphrodite genitalia development GO:0040035 734 0.033
single organism organelle organization GO:1902589 501 0.032
regulation of growth GO:0040008 409 0.032
cell cycle GO:0007049 526 0.032
chromosome organization GO:0051276 104 0.032
cell division GO:0051301 262 0.032
cellular protein metabolic process GO:0044267 279 0.032
endocytosis GO:0006897 819 0.031
generation of neurons GO:0048699 235 0.031
regulation of nucleic acid templated transcription GO:1903506 165 0.031
genitalia development GO:0048806 741 0.031
negative regulation of developmental process GO:0051093 227 0.030
regulation of cellular metabolic process GO:0031323 305 0.030
positive regulation of developmental process GO:0051094 408 0.030
secretion GO:0046903 147 0.029
regulation of cell communication GO:0010646 176 0.029
organic cyclic compound biosynthetic process GO:1901362 195 0.027
oxoacid metabolic process GO:0043436 47 0.027
regulation of cellular biosynthetic process GO:0031326 189 0.026
response to abiotic stimulus GO:0009628 152 0.026
cellular macromolecular complex assembly GO:0034622 184 0.026
meiotic chromosome segregation GO:0045132 139 0.025
cellular protein complex assembly GO:0043623 178 0.025
meiotic cell cycle process GO:1903046 170 0.025
signaling GO:0023052 401 0.024
positive regulation of growth GO:0045927 369 0.023
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.023
cell proliferation GO:0008283 116 0.023
regulation of multicellular organism growth GO:0040014 373 0.023
organelle assembly GO:0070925 214 0.023
oogenesis GO:0048477 229 0.023
cytoskeleton organization GO:0007010 339 0.023
head development GO:0060322 1 0.022
reproductive system development GO:0061458 850 0.022
regulation of signaling GO:0023051 172 0.022
regulation of cell cycle process GO:0010564 145 0.022
actin filament based process GO:0030029 191 0.022
receptor mediated endocytosis GO:0006898 715 0.022
regulation of biosynthetic process GO:0009889 189 0.022
actomyosin structure organization GO:0031032 154 0.021
catabolic process GO:0009056 318 0.021
histone modification GO:0016570 30 0.021
macromolecule catabolic process GO:0009057 202 0.021
intracellular signal transduction GO:0035556 96 0.021
negative regulation of macromolecule metabolic process GO:0010605 229 0.021
macromolecular complex subunit organization GO:0043933 320 0.020
nervous system development GO:0007399 253 0.020
myosin filament assembly GO:0031034 138 0.020
negative regulation of gene expression GO:0010629 217 0.019
positive regulation of multicellular organism growth GO:0040018 352 0.019
cellular biosynthetic process GO:0044249 315 0.019
negative regulation of nematode larval development GO:0061064 208 0.019
macromolecular complex assembly GO:0065003 193 0.019
organic acid metabolic process GO:0006082 47 0.019
anatomical structure formation involved in morphogenesis GO:0048646 250 0.018
striated muscle cell development GO:0055002 157 0.018
cellular response to abiotic stimulus GO:0071214 4 0.018
positive regulation of developmental growth GO:0048639 354 0.018
regulation of cell differentiation GO:0045595 81 0.018
protein complex assembly GO:0006461 186 0.017
organic substance catabolic process GO:1901575 294 0.017
regulation of apoptotic signaling pathway GO:2001233 1 0.017
regulation of cell proliferation GO:0042127 105 0.017
neuron differentiation GO:0030182 217 0.017
neurogenesis GO:0022008 236 0.017
regulation of epithelial cell proliferation GO:0050678 1 0.017
cellular component morphogenesis GO:0032989 318 0.017
posttranscriptional gene silencing GO:0016441 143 0.016
signal transduction GO:0007165 317 0.016
regulation of nuclear division GO:0051783 115 0.016
skeletal muscle organ development GO:0060538 3 0.016
positive regulation of macromolecule metabolic process GO:0010604 149 0.016
rna interference GO:0016246 137 0.016
regulation of cytoplasmic transport GO:1903649 3 0.016
muscle tissue development GO:0060537 1 0.016
proteolysis GO:0006508 61 0.016
protein catabolic process GO:0030163 162 0.016
response to wounding GO:0009611 4 0.015
regulation of cellular component organization GO:0051128 248 0.015
positive regulation of biosynthetic process GO:0009891 109 0.015
system process GO:0003008 136 0.015
regulation of vulval development GO:0040028 248 0.015
single organism biosynthetic process GO:0044711 91 0.015
protein complex biogenesis GO:0070271 186 0.014
actin cytoskeleton organization GO:0030036 184 0.014
biosynthetic process GO:0009058 323 0.014
nucleobase containing compound biosynthetic process GO:0034654 184 0.014
transcription from rna polymerase ii promoter GO:0006366 149 0.014
negative regulation of post embryonic development GO:0048581 208 0.013
muscle cell differentiation GO:0042692 171 0.013
multicellular organism growth GO:0035264 385 0.013
cellular nitrogen compound biosynthetic process GO:0044271 192 0.013
protein phosphorylation GO:0006468 85 0.013
regulation of response to stimulus GO:0048583 243 0.013
sex differentiation GO:0007548 909 0.013
carboxylic acid metabolic process GO:0019752 34 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.013
positive regulation of transcription dna templated GO:0045893 102 0.013
posttranscriptional regulation of gene expression GO:0010608 166 0.013
response to external stimulus GO:0009605 289 0.012
regulation of organelle organization GO:0033043 164 0.012
myosin filament organization GO:0031033 138 0.012
cellular component assembly involved in morphogenesis GO:0010927 183 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.012
cellular amino acid metabolic process GO:0006520 15 0.012
cellular response to stress GO:0033554 162 0.012
negative regulation of vulval development GO:0040027 206 0.012
neurological system process GO:0050877 53 0.012
regulation of cellular ketone metabolic process GO:0010565 3 0.012
neuron apoptotic process GO:0051402 4 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.012
cell surface receptor signaling pathway GO:0007166 149 0.012
muscle structure development GO:0061061 191 0.011
positive regulation of signal transduction GO:0009967 40 0.011
cuticle development GO:0042335 100 0.011
response to chemical GO:0042221 356 0.011
adult behavior GO:0030534 3 0.011
gene silencing by rna GO:0031047 143 0.011
muscle cell development GO:0055001 158 0.011
ubiquitin dependent protein catabolic process GO:0006511 32 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 32 0.011
single organism behavior GO:0044708 83 0.011
striated muscle cell differentiation GO:0051146 158 0.011
striated muscle myosin thick filament assembly GO:0071688 138 0.011
negative regulation of response to stimulus GO:0048585 73 0.011
synaptic growth at neuromuscular junction GO:0051124 1 0.011
positive regulation of metabolic process GO:0009893 187 0.011
myofibril assembly GO:0030239 154 0.011
secretion by cell GO:0032940 138 0.010
posttranscriptional gene silencing by rna GO:0035194 143 0.010
collagen and cuticulin based cuticle development GO:0040002 99 0.010
positive regulation of signaling GO:0023056 66 0.010
cell cell signaling GO:0007267 118 0.010

sir-2.4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org