Caenorhabditis elegans

173 known processes

dcr-1 (CELE_K12H4.8)

Protein DCR-1

dcr-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
meiotic nuclear division GO:0007126 300 0.986
embryo development ending in birth or egg hatching GO:0009792 2992 0.851
Worm
chromosome segregation GO:0007059 180 0.814
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.742
Mouse
embryo development GO:0009790 3052 0.738
Mouse Worm Fly
organelle fission GO:0048285 363 0.657
post embryonic development GO:0009791 2152 0.623
chromosome organization GO:0051276 104 0.603
mitotic sister chromatid segregation GO:0000070 38 0.597
regulation of gene expression epigenetic GO:0040029 163 0.548
mitotic nuclear division GO:0007067 89 0.533
neurogenesis GO:0022008 236 0.529
Mouse Fly
regulation of cellular metabolic process GO:0031323 305 0.519
organic substance catabolic process GO:1901575 294 0.503
regulation of organelle organization GO:0033043 164 0.494
establishment of localization GO:0051234 1171 0.493
Fly
meiotic cell cycle process GO:1903046 170 0.486
reproductive structure development GO:0048608 850 0.475
positive regulation of cellular process GO:0048522 332 0.473
regulation of cellular component organization GO:0051128 248 0.466
locomotion GO:0040011 1634 0.458
organic cyclic compound biosynthetic process GO:1901362 195 0.417
Mouse
meiotic chromosome segregation GO:0045132 139 0.390
rna metabolic process GO:0016070 228 0.379
gene expression GO:0010467 412 0.375
single organism organelle organization GO:1902589 501 0.373
Mouse
aromatic compound biosynthetic process GO:0019438 192 0.367
Mouse
protein metabolic process GO:0019538 422 0.348
Mouse
regulation of primary metabolic process GO:0080090 292 0.342
gamete generation GO:0007276 461 0.335
Worm Fly
dna conformation change GO:0071103 11 0.334
multicellular organism reproduction GO:0032504 819 0.326
regulation of macromolecule biosynthetic process GO:0010556 189 0.322
Mouse
cell cycle GO:0007049 526 0.307
catabolic process GO:0009056 318 0.307
protein localization GO:0008104 205 0.306
cellular localization GO:0051641 360 0.294
organelle organization GO:0006996 783 0.286
sister chromatid segregation GO:0000819 46 0.281
regulation of developmental process GO:0050793 684 0.281
cellular nitrogen compound biosynthetic process GO:0044271 192 0.273
Mouse
hermaphrodite genitalia development GO:0040035 734 0.271
negative regulation of gene expression GO:0010629 217 0.269
development of primary sexual characteristics GO:0045137 840 0.266
mitotic cell cycle process GO:1903047 194 0.255
multicellular organismal reproductive behavior GO:0033057 384 0.253
multicellular organismal reproductive process GO:0048609 815 0.253
signaling GO:0023052 401 0.248
nucleobase containing compound metabolic process GO:0006139 406 0.245
programmed cell death GO:0012501 500 0.240
cellular component morphogenesis GO:0032989 318 0.237
Mouse Fly
cell morphogenesis GO:0000902 163 0.237
Mouse Fly
cell cycle process GO:0022402 482 0.234
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.230
Fly
developmental process involved in reproduction GO:0003006 1165 0.229
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.228
negative regulation of gene expression epigenetic GO:0045814 2 0.219
regulation of rna metabolic process GO:0051252 173 0.208
cellular response to dna damage stimulus GO:0006974 41 0.207
Worm
cellular macromolecule biosynthetic process GO:0034645 247 0.200
Mouse
dna repair GO:0006281 23 0.199
regulation of biosynthetic process GO:0009889 189 0.198
Mouse
nucleic acid metabolic process GO:0090304 299 0.178
chromosome organization involved in meiosis GO:0070192 25 0.174
macromolecule localization GO:0033036 771 0.174
Fly
cellular catabolic process GO:0044248 199 0.172
regulation of macromolecule metabolic process GO:0060255 421 0.170
macromolecule catabolic process GO:0009057 202 0.168
cellular protein localization GO:0034613 75 0.165
establishment of localization in cell GO:0051649 318 0.165
regulation of response to stimulus GO:0048583 243 0.163
negative regulation of cellular process GO:0048523 239 0.162
Mouse
negative regulation of metabolic process GO:0009892 240 0.160
apoptotic process GO:0006915 478 0.158
regulation of nitrogen compound metabolic process GO:0051171 222 0.154
response to abiotic stimulus GO:0009628 152 0.151
nucleic acid templated transcription GO:0097659 169 0.151
Mouse
regulation of metabolic process GO:0019222 478 0.149
covalent chromatin modification GO:0016569 30 0.149
heterocycle biosynthetic process GO:0018130 187 0.149
Mouse
sexual reproduction GO:0019953 546 0.148
Worm Fly
meiotic cell cycle GO:0051321 335 0.148
negative regulation of macromolecule metabolic process GO:0010605 229 0.148
regulation of transcription dna templated GO:0006355 164 0.146
Mouse
regulation of nuclear division GO:0051783 115 0.146
cellular response to stress GO:0033554 162 0.146
Worm
gonad development GO:0008406 840 0.146
rna biosynthetic process GO:0032774 169 0.145
Mouse
multi organism reproductive process GO:0044703 867 0.144
regulation of multicellular organismal development GO:2000026 317 0.134
Mouse
nucleobase containing compound biosynthetic process GO:0034654 184 0.134
Mouse
single organism reproductive process GO:0044702 1196 0.133
sex differentiation GO:0007548 909 0.133
response to wounding GO:0009611 4 0.132
Mouse
macromolecular complex subunit organization GO:0043933 320 0.127
Human Mouse Fly
organ development GO:0048513 1102 0.126
positive regulation of metabolic process GO:0009893 187 0.124
dna metabolic process GO:0006259 74 0.122
intracellular receptor signaling pathway GO:0030522 2 0.121
cell part morphogenesis GO:0032990 152 0.118
Mouse Fly
positive regulation of macromolecule metabolic process GO:0010604 149 0.117
transport GO:0006810 1093 0.115
Fly
cell death GO:0008219 547 0.113
histone modification GO:0016570 30 0.113
production of sirna involved in rna interference GO:0030422 6 0.111
regulation of gene expression GO:0010468 366 0.110
cytoskeleton organization GO:0007010 339 0.110
Mouse
regulation of cell division GO:0051302 142 0.106
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.106
multi organism behavior GO:0051705 389 0.105
positive regulation of cellular biosynthetic process GO:0031328 109 0.103
Mouse
regulation of cell cycle process GO:0010564 145 0.100
transcription dna templated GO:0006351 168 0.100
Mouse
regulation of cellular biosynthetic process GO:0031326 189 0.100
Mouse
rna localization GO:0006403 3 0.100
Fly
regulation of rna biosynthetic process GO:2001141 165 0.100
Mouse
chromatin modification GO:0016568 32 0.099
growth GO:0040007 562 0.098
Mouse
regulation of cell proliferation GO:0042127 105 0.095
Mouse
single organism localization GO:1902578 518 0.094
Fly
neuron projection development GO:0031175 187 0.094
Mouse Fly
protein catabolic process GO:0030163 162 0.092
protein modification process GO:0036211 207 0.091
Mouse
ribonucleoside monophosphate metabolic process GO:0009161 45 0.090
Worm
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.087
Mouse
organic substance biosynthetic process GO:1901576 323 0.086
Mouse
cellular biosynthetic process GO:0044249 315 0.085
Mouse
regulation of nucleic acid templated transcription GO:1903506 165 0.084
Mouse
single organism catabolic process GO:0044712 129 0.084
Worm
cellular component movement GO:0006928 388 0.083
microtubule based process GO:0007017 182 0.083
Mouse
response to external stimulus GO:0009605 289 0.082
Mouse Fly
body morphogenesis GO:0010171 620 0.082
negative regulation of nucleic acid templated transcription GO:1903507 53 0.082
Mouse
genitalia development GO:0048806 741 0.082
regulation of meiosis GO:0040020 94 0.080
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.079
Mouse
phosphate containing compound metabolic process GO:0006796 232 0.079
Mouse Worm
regulation of signal transduction GO:0009966 135 0.078
cellular protein metabolic process GO:0044267 279 0.078
Mouse
organonitrogen compound metabolic process GO:1901564 151 0.078
Worm
signal transduction GO:0007165 317 0.078
regulation of cell cycle GO:0051726 194 0.077
Mouse
gene silencing GO:0016458 143 0.076
regulation of multicellular organismal process GO:0051239 726 0.075
Mouse
positive regulation of cellular metabolic process GO:0031325 178 0.075
nervous system development GO:0007399 253 0.074
Zebrafish Mouse Fly
regulation of localization GO:0032879 194 0.073
single organism transport GO:0044765 447 0.072
Fly
developmental growth GO:0048589 412 0.072
Mouse
reproductive behavior GO:0019098 387 0.072
neuron projection morphogenesis GO:0048812 114 0.069
Mouse Fly
head development GO:0060322 1 0.067
Zebrafish Mouse
vulval development GO:0040025 333 0.067
cellular macromolecule localization GO:0070727 75 0.065
negative regulation of biological process GO:0048519 567 0.065
cellular protein modification process GO:0006464 207 0.063
Mouse
lipid storage GO:0019915 565 0.063
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.063
Mouse
maintenance of location GO:0051235 580 0.061
maintenance of protein location GO:0045185 15 0.060
lipid localization GO:0010876 573 0.060
protein complex subunit organization GO:0071822 280 0.059
Mouse
regulation of growth GO:0040008 409 0.058
cell migration GO:0016477 306 0.057
single organism signaling GO:0044700 401 0.056
multi organism reproductive behavior GO:0044705 387 0.056
cellular nitrogen compound catabolic process GO:0044270 119 0.055
proteolysis GO:0006508 61 0.055
negative regulation of rna metabolic process GO:0051253 53 0.053
Mouse
regulation of biological quality GO:0065008 741 0.053
Mouse
post embryonic organ development GO:0048569 336 0.053
macromolecule modification GO:0043412 218 0.053
Mouse
behavior GO:0007610 527 0.052
chromatin organization GO:0006325 32 0.052
regulation of cell communication GO:0010646 176 0.052
generation of neurons GO:0048699 235 0.052
Mouse Fly
aromatic compound catabolic process GO:0019439 116 0.051
regulation of cell death GO:0010941 65 0.050
Mouse
rna interference GO:0016246 137 0.050
rna processing GO:0006396 34 0.049
cell type specific apoptotic process GO:0097285 4 0.048
Mouse
cell motility GO:0048870 313 0.048
purine nucleoside metabolic process GO:0042278 92 0.047
Worm
death GO:0016265 547 0.047
negative regulation of cellular metabolic process GO:0031324 95 0.045
Mouse
mrna metabolic process GO:0016071 31 0.045
Zebrafish
muscle tissue development GO:0060537 1 0.045
Mouse
cell proliferation GO:0008283 116 0.043
Mouse Fly
cell development GO:0048468 696 0.043
Mouse Fly
positive regulation of chromosome organization GO:2001252 2 0.042
macromolecule biosynthetic process GO:0009059 250 0.041
Mouse
cell division GO:0051301 262 0.041
Mouse Fly
regulation of chromosome organization GO:0033044 20 0.041
regulation of mitosis GO:0007088 18 0.041
neuron differentiation GO:0030182 217 0.040
Mouse Fly
regulation of signaling GO:0023051 172 0.040
determination of adult lifespan GO:0008340 812 0.040
dna templated transcription elongation GO:0006354 1 0.039
organic cyclic compound catabolic process GO:1901361 119 0.039
endocytosis GO:0006897 819 0.039
positive regulation of response to stimulus GO:0048584 55 0.039
negative regulation of rna biosynthetic process GO:1902679 53 0.038
Mouse
dna recombination GO:0006310 19 0.038
single fertilization GO:0007338 61 0.038
cell morphogenesis involved in differentiation GO:0000904 112 0.037
Fly
cell projection morphogenesis GO:0048858 148 0.037
Mouse Fly
multicellular organismal aging GO:0010259 812 0.035
vesicle mediated transport GO:0016192 852 0.035
positive regulation of multicellular organismal process GO:0051240 417 0.035
Mouse
posttranscriptional gene silencing GO:0016441 143 0.035
nucleoside metabolic process GO:0009116 99 0.035
Worm
purine ribonucleoside monophosphate catabolic process GO:0009169 28 0.034
Worm
localization of cell GO:0051674 313 0.034
posttranscriptional gene silencing by rna GO:0035194 143 0.034
transcription elongation from rna polymerase ii promoter GO:0006368 1 0.034
organic substance transport GO:0071702 113 0.033
Fly
negative regulation of developmental process GO:0051093 227 0.032
Mouse
germ cell development GO:0007281 351 0.031
Fly
anatomical structure formation involved in morphogenesis GO:0048646 250 0.031
Mouse Fly
aging GO:0007568 812 0.031
neuron projection guidance GO:0097485 82 0.030
positive regulation of developmental process GO:0051094 408 0.030
Mouse
regulation of anatomical structure morphogenesis GO:0022603 51 0.030
Mouse
spermatogenesis GO:0007283 41 0.030
oviposition GO:0018991 364 0.030
transcription from rna polymerase ii promoter GO:0006366 149 0.030
Mouse
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.030
Fly
single organism cellular localization GO:1902580 72 0.029
negative regulation of cellular biosynthetic process GO:0031327 65 0.029
Mouse
positive regulation of signaling GO:0023056 66 0.029
cellular macromolecular complex assembly GO:0034622 184 0.029
Human Fly
intracellular signal transduction GO:0035556 96 0.029
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.029
Mouse
spindle organization GO:0007051 92 0.029
Mouse
receptor mediated endocytosis GO:0006898 715 0.029
biosynthetic process GO:0009058 323 0.029
Mouse
dna duplex unwinding GO:0032508 3 0.028
regulation of developmental growth GO:0048638 389 0.028
gene silencing by rna GO:0031047 143 0.028
cellular component biogenesis GO:0044085 297 0.027
Human Mouse Fly
purine nucleoside monophosphate metabolic process GO:0009126 43 0.027
Worm
organophosphate metabolic process GO:0019637 125 0.027
Worm
positive regulation of multicellular organism growth GO:0040018 352 0.027
protein phosphorylation GO:0006468 85 0.027
Mouse
maintenance of location in cell GO:0051651 12 0.027
organelle localization GO:0051640 127 0.026
regulation of intracellular signal transduction GO:1902531 77 0.026
tissue development GO:0009888 112 0.026
Mouse
regulation of multicellular organism growth GO:0040014 373 0.026
regulation of chromatin modification GO:1903308 2 0.026
regulation of programmed cell death GO:0043067 50 0.026
Mouse
negative regulation of vulval development GO:0040027 206 0.026
dna packaging GO:0006323 7 0.026
positive regulation of biosynthetic process GO:0009891 109 0.025
Mouse
regulation of locomotion GO:0040012 161 0.025
muscle cell differentiation GO:0042692 171 0.025
Mouse
actomyosin structure organization GO:0031032 154 0.025
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.025
Mouse
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.025
Mouse
reproductive system development GO:0061458 850 0.024
atp catabolic process GO:0006200 27 0.024
Worm
internal peptidyl lysine acetylation GO:0018393 3 0.024
system process GO:0003008 136 0.024
positive regulation of growth GO:0045927 369 0.024
response to organic substance GO:0010033 131 0.024
nucleic acid phosphodiester bond hydrolysis GO:0090305 28 0.024
secretion by cell GO:0032940 138 0.024
cellular component assembly GO:0022607 293 0.023
Human Mouse Fly
peptidyl amino acid modification GO:0018193 58 0.023
male gamete generation GO:0048232 41 0.023
glycosyl compound metabolic process GO:1901657 100 0.023
Worm
inductive cell migration GO:0040039 145 0.023
negative regulation of multicellular organismal process GO:0051241 236 0.022
Mouse
regulation of cell differentiation GO:0045595 81 0.022
Mouse
regulation of mitotic cell cycle GO:0007346 76 0.022
multicellular organism growth GO:0035264 385 0.021
Mouse
muscle structure development GO:0061061 191 0.021
Mouse
nucleoside monophosphate metabolic process GO:0009123 46 0.021
Worm
positive regulation of cellular component organization GO:0051130 34 0.021
regulation of cellular amino acid metabolic process GO:0006521 0 0.020
regulation of vulval development GO:0040028 248 0.020
positive regulation of developmental growth GO:0048639 354 0.020
striated muscle cell differentiation GO:0051146 158 0.020
Mouse
posttranscriptional regulation of gene expression GO:0010608 166 0.020
negative regulation of transcription dna templated GO:0045892 53 0.019
Mouse
dendrite development GO:0016358 42 0.019
Fly
establishment of nucleus localization GO:0040023 55 0.019
cellular macromolecule catabolic process GO:0044265 73 0.019
chromatin assembly GO:0031497 1 0.019
regulation of chromosome segregation GO:0051983 20 0.019
actin filament based process GO:0030029 191 0.019
macromolecular complex assembly GO:0065003 193 0.019
Human Mouse Fly
carboxylic acid metabolic process GO:0019752 34 0.019
glycosyl compound catabolic process GO:1901658 79 0.019
Worm
neuron development GO:0048666 199 0.018
Mouse Fly
regulation of phosphate metabolic process GO:0019220 81 0.018
Mouse
striated muscle cell development GO:0055002 157 0.018
Mouse
cellular protein complex assembly GO:0043623 178 0.018
response to heat GO:0009408 50 0.018
cell projection organization GO:0030030 231 0.018
Mouse Fly
positive regulation of nucleic acid templated transcription GO:1903508 102 0.017
Mouse
nucleoside monophosphate catabolic process GO:0009125 28 0.017
Worm
response to chemical GO:0042221 356 0.017
regulation of protein import into nucleus GO:0042306 3 0.017
protein complex assembly GO:0006461 186 0.017
Mouse
maintenance of protein location in cell GO:0032507 12 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.017
purine ribonucleoside monophosphate metabolic process GO:0009167 43 0.017
Worm
regulation of meiotic cell cycle GO:0051445 136 0.017
axonogenesis GO:0007409 102 0.016
amine metabolic process GO:0009308 15 0.016
regulation of protein localization GO:0032880 50 0.016
pronuclear migration GO:0035046 51 0.016
metaphase anaphase transition of cell cycle GO:0044784 15 0.016
small molecule metabolic process GO:0044281 186 0.016
Worm
meiosis i GO:0007127 19 0.016
nuclear migration GO:0007097 54 0.016
pigmentation GO:0043473 2 0.015
chemotaxis GO:0006935 120 0.015
ribose phosphate metabolic process GO:0019693 99 0.015
Worm
regulation of molecular function GO:0065009 89 0.015
secretion GO:0046903 147 0.015
regulation of cellular protein metabolic process GO:0032268 75 0.015
Mouse
negative regulation of nematode larval development GO:0061064 208 0.015
modification dependent protein catabolic process GO:0019941 32 0.014
regulation of cell morphogenesis GO:0022604 40 0.014
organelle assembly GO:0070925 214 0.014
Mouse
purine nucleoside monophosphate catabolic process GO:0009128 28 0.014
Worm
chromosome separation GO:0051304 19 0.014
regulation of multi organism process GO:0043900 69 0.014
Mouse
dosage compensation by hypoactivation of x chromosome GO:0042464 11 0.014
purine ribonucleoside catabolic process GO:0046130 75 0.014
Worm
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.014
myofibril assembly GO:0030239 154 0.014
atp metabolic process GO:0046034 42 0.014
Worm
regulation of cellular ketone metabolic process GO:0010565 3 0.013
muscle cell development GO:0055001 158 0.013
Mouse
response to organic cyclic compound GO:0014070 10 0.013
taxis GO:0042330 128 0.013
regulation of chromatin organization GO:1902275 2 0.013
regulation of nematode larval development GO:0061062 260 0.013
protein transport GO:0015031 45 0.013
cellular amine metabolic process GO:0044106 15 0.013
mitotic sister chromatid separation GO:0051306 13 0.013
establishment of organelle localization GO:0051656 123 0.013
dna replication GO:0006260 15 0.013
negative regulation of post embryonic development GO:0048581 208 0.013
ribonucleoside metabolic process GO:0009119 98 0.013
Worm
purine nucleoside catabolic process GO:0006152 75 0.013
Worm
regulation of mitotic sister chromatid segregation GO:0033047 16 0.013
nucleus organization GO:0006997 38 0.013
protein complex biogenesis GO:0070271 186 0.013
Mouse
regulation of protein targeting GO:1903533 3 0.013
regulation of nucleocytoplasmic transport GO:0046822 3 0.012
protein localization to organelle GO:0033365 37 0.012
actin cytoskeleton organization GO:0030036 184 0.012
metaphase anaphase transition of mitotic cell cycle GO:0007091 10 0.012
regulation of post embryonic development GO:0048580 260 0.012
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.012
Mouse
rna catabolic process GO:0006401 21 0.012
regulation of histone modification GO:0031056 1 0.012
regulation of dna metabolic process GO:0051052 14 0.012
positive regulation of cell communication GO:0010647 69 0.012
embryonic morphogenesis GO:0048598 152 0.012
Mouse
regulation of histone methylation GO:0031060 1 0.012
nucleus localization GO:0051647 55 0.012
striated muscle myosin thick filament assembly GO:0071688 138 0.011
collagen and cuticulin based cuticle development GO:0040002 99 0.011
internal protein amino acid acetylation GO:0006475 3 0.011
ribonucleotide catabolic process GO:0009261 75 0.011
Worm
regulation of sister chromatid segregation GO:0033045 16 0.011
multi multicellular organism process GO:0044706 390 0.011
chromatin remodeling GO:0006338 2 0.011
cuticle development GO:0042335 100 0.011
positive regulation of protein metabolic process GO:0051247 45 0.011
purine containing compound catabolic process GO:0072523 75 0.011
Worm
sensory organ morphogenesis GO:0090596 2 0.011
ribonucleotide metabolic process GO:0009259 99 0.011
Worm
regulation of cellular amine metabolic process GO:0033238 0 0.011
response to inorganic substance GO:0010035 50 0.011
cellular response to organic substance GO:0071310 119 0.011
response to other organism GO:0051707 101 0.011
Mouse
peptidyl lysine acetylation GO:0018394 3 0.011
regulation of apoptotic process GO:0042981 36 0.011
Mouse
negative regulation of response to stimulus GO:0048585 73 0.011
immune response GO:0006955 192 0.011
female gamete generation GO:0007292 254 0.011
Fly
establishment of protein localization GO:0045184 50 0.010
peptidyl lysine modification GO:0018205 10 0.010
cellular response to chemical stimulus GO:0070887 129 0.010
myosin filament organization GO:0031033 138 0.010
regulation of protein metabolic process GO:0051246 81 0.010
Mouse
positive regulation of transferase activity GO:0051347 21 0.010
regulation of apoptotic signaling pathway GO:2001233 1 0.010
organonitrogen compound catabolic process GO:1901565 90 0.010
Worm
proteasomal protein catabolic process GO:0010498 20 0.010
nucleoside catabolic process GO:0009164 78 0.010
Worm

dcr-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.023
Human