Caenorhabditis elegans

15 known processes

lea-1 (CELE_K08H10.1)

Protein LEA-1

lea-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
multicellular organismal reproductive process GO:0048609 815 0.316
embryo development ending in birth or egg hatching GO:0009792 2992 0.291
post embryonic development GO:0009791 2152 0.168
embryo development GO:0009790 3052 0.165
negative regulation of macromolecule metabolic process GO:0010605 229 0.163
gamete generation GO:0007276 461 0.160
multi organism reproductive process GO:0044703 867 0.151
multicellular organism reproduction GO:0032504 819 0.125
single organism reproductive process GO:0044702 1196 0.121
gene expression GO:0010467 412 0.112
reproductive system development GO:0061458 850 0.112
regulation of biological quality GO:0065008 741 0.111
cellular response to dna damage stimulus GO:0006974 41 0.107
vesicle mediated transport GO:0016192 852 0.105
genitalia development GO:0048806 741 0.097
neuron differentiation GO:0030182 217 0.095
sexual reproduction GO:0019953 546 0.094
gonad development GO:0008406 840 0.093
chromatin organization GO:0006325 32 0.092
aging GO:0007568 812 0.090
single organism organelle organization GO:1902589 501 0.086
nervous system development GO:0007399 253 0.084
apoptotic process GO:0006915 478 0.084
growth GO:0040007 562 0.083
regulation of rna biosynthetic process GO:2001141 165 0.081
developmental process involved in reproduction GO:0003006 1165 0.078
regulation of gene expression epigenetic GO:0040029 163 0.077
macromolecular complex subunit organization GO:0043933 320 0.074
cellular response to organic substance GO:0071310 119 0.074
response to chemical GO:0042221 356 0.071
lipid storage GO:0019915 565 0.070
locomotion GO:0040011 1634 0.070
response to heat GO:0009408 50 0.070
generation of neurons GO:0048699 235 0.070
multicellular organismal aging GO:0010259 812 0.068
determination of adult lifespan GO:0008340 812 0.068
aromatic compound biosynthetic process GO:0019438 192 0.065
cell projection organization GO:0030030 231 0.065
cellular nitrogen compound biosynthetic process GO:0044271 192 0.064
receptor mediated endocytosis GO:0006898 715 0.063
developmental growth GO:0048589 412 0.061
lipid localization GO:0010876 573 0.060
neurogenesis GO:0022008 236 0.057
maintenance of location GO:0051235 580 0.057
regulation of nitrogen compound metabolic process GO:0051171 222 0.057
macromolecule localization GO:0033036 771 0.055
cell motility GO:0048870 313 0.055
development of primary sexual characteristics GO:0045137 840 0.055
oviposition GO:0018991 364 0.052
cell development GO:0048468 696 0.052
neuron projection morphogenesis GO:0048812 114 0.052
defense response GO:0006952 296 0.052
cell part morphogenesis GO:0032990 152 0.050
cellular component morphogenesis GO:0032989 318 0.050
rna biosynthetic process GO:0032774 169 0.049
cell morphogenesis GO:0000902 163 0.048
regulation of metabolic process GO:0019222 478 0.048
regulation of gene expression GO:0010468 366 0.046
chromosome organization GO:0051276 104 0.045
cell morphogenesis involved in differentiation GO:0000904 112 0.045
multi multicellular organism process GO:0044706 390 0.045
death GO:0016265 547 0.044
muscle cell differentiation GO:0042692 171 0.043
muscle tissue development GO:0060537 1 0.041
reproductive behavior GO:0019098 387 0.040
macromolecule modification GO:0043412 218 0.040
regulation of rna metabolic process GO:0051252 173 0.039
response to abiotic stimulus GO:0009628 152 0.038
regulation of biosynthetic process GO:0009889 189 0.038
cell surface receptor signaling pathway GO:0007166 149 0.038
regulation of macromolecule metabolic process GO:0060255 421 0.038
cellular component movement GO:0006928 388 0.036
organelle organization GO:0006996 783 0.036
rna interference GO:0016246 137 0.036
cell type specific apoptotic process GO:0097285 4 0.035
behavior GO:0007610 527 0.035
multi organism reproductive behavior GO:0044705 387 0.035
skeletal muscle organ development GO:0060538 3 0.035
carboxylic acid metabolic process GO:0019752 34 0.034
defense response to other organism GO:0098542 100 0.033
cell division GO:0051301 262 0.033
localization of cell GO:0051674 313 0.033
multi organism behavior GO:0051705 389 0.033
response to biotic stimulus GO:0009607 101 0.033
response to external stimulus GO:0009605 289 0.033
reproductive structure development GO:0048608 850 0.032
negative regulation of metabolic process GO:0009892 240 0.031
regulation of transcription dna templated GO:0006355 164 0.031
female gamete generation GO:0007292 254 0.031
cell projection morphogenesis GO:0048858 148 0.030
regulation of primary metabolic process GO:0080090 292 0.030
regulation of multicellular organismal process GO:0051239 726 0.030
cellular protein modification process GO:0006464 207 0.030
endoplasmic reticulum unfolded protein response GO:0030968 66 0.030
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.029
regulation of developmental process GO:0050793 684 0.029
innate immune response GO:0045087 190 0.029
sex differentiation GO:0007548 909 0.029
muscle structure development GO:0061061 191 0.028
regulation of cellular biosynthetic process GO:0031326 189 0.028
nucleobase containing compound metabolic process GO:0006139 406 0.028
meiotic cell cycle process GO:1903046 170 0.028
negative regulation of cellular process GO:0048523 239 0.028
nucleobase containing compound biosynthetic process GO:0034654 184 0.027
head development GO:0060322 1 0.026
transcription from rna polymerase ii promoter GO:0006366 149 0.025
protein metabolic process GO:0019538 422 0.024
anatomical structure formation involved in morphogenesis GO:0048646 250 0.024
regulation of nucleic acid templated transcription GO:1903506 165 0.023
multicellular organism growth GO:0035264 385 0.023
positive regulation of multicellular organism growth GO:0040018 352 0.023
positive regulation of growth GO:0045927 369 0.023
cellular biosynthetic process GO:0044249 315 0.023
cellular component assembly involved in morphogenesis GO:0010927 183 0.023
endocytosis GO:0006897 819 0.023
protein complex subunit organization GO:0071822 280 0.022
regulation of filopodium assembly GO:0051489 2 0.022
striated muscle cell differentiation GO:0051146 158 0.022
cellular localization GO:0051641 360 0.022
regulation of organelle organization GO:0033043 164 0.022
signal transduction GO:0007165 317 0.022
gene silencing GO:0016458 143 0.022
posttranscriptional regulation of gene expression GO:0010608 166 0.021
negative regulation of developmental process GO:0051093 227 0.021
post embryonic organ development GO:0048569 336 0.021
transport GO:0006810 1093 0.021
immune response GO:0006955 192 0.021
regulation of multicellular organism growth GO:0040014 373 0.021
regulation of macromolecule biosynthetic process GO:0010556 189 0.020
organic acid metabolic process GO:0006082 47 0.020
epithelial tube morphogenesis GO:0060562 1 0.020
organ development GO:0048513 1102 0.020
myofibril assembly GO:0030239 154 0.020
regulation of signal transduction GO:0009966 135 0.020
multicellular organismal reproductive behavior GO:0033057 384 0.020
response to other organism GO:0051707 101 0.019
positive regulation of macromolecule metabolic process GO:0010604 149 0.019
response to external biotic stimulus GO:0043207 101 0.019
regulation of developmental growth GO:0048638 389 0.019
signaling GO:0023052 401 0.019
biosynthetic process GO:0009058 323 0.019
regulation of cellular metabolic process GO:0031323 305 0.019
cellular response to chemical stimulus GO:0070887 129 0.019
positive regulation of response to stimulus GO:0048584 55 0.018
posttranscriptional gene silencing GO:0016441 143 0.018
development of primary male sexual characteristics GO:0046546 4 0.018
cell death GO:0008219 547 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.018
protein modification process GO:0036211 207 0.018
rna metabolic process GO:0016070 228 0.017
meiotic cell cycle GO:0051321 335 0.017
sensory organ morphogenesis GO:0090596 2 0.017
defense response to bacterium GO:0042742 86 0.017
posttranscriptional gene silencing by rna GO:0035194 143 0.017
positive regulation of defense response GO:0031349 6 0.017
internal peptidyl lysine acetylation GO:0018393 3 0.017
actin filament based process GO:0030029 191 0.017
regulation of cellular component organization GO:0051128 248 0.017
hermaphrodite genitalia development GO:0040035 734 0.017
establishment of localization GO:0051234 1171 0.017
cellular protein metabolic process GO:0044267 279 0.017
positive regulation of developmental growth GO:0048639 354 0.017
translational elongation GO:0006414 1 0.017
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.017
regulation of apoptotic signaling pathway GO:2001233 1 0.017
programmed cell death GO:0012501 500 0.017
cellular amino acid metabolic process GO:0006520 15 0.017
protein complex biogenesis GO:0070271 186 0.017
heterocycle biosynthetic process GO:0018130 187 0.016
negative regulation of biological process GO:0048519 567 0.016
cellular catabolic process GO:0044248 199 0.016
purine nucleotide metabolic process GO:0006163 95 0.016
dna templated transcription elongation GO:0006354 1 0.016
neuron projection guidance GO:0097485 82 0.016
defense response to gram negative bacterium GO:0050829 64 0.016
negative regulation of gene expression GO:0010629 217 0.015
activation of ras gtpase activity GO:0032856 3 0.015
catabolic process GO:0009056 318 0.015
nucleic acid templated transcription GO:0097659 169 0.015
germ cell development GO:0007281 351 0.014
production of sirna involved in rna interference GO:0030422 6 0.014
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.014
neuron development GO:0048666 199 0.014
neuron projection development GO:0031175 187 0.014
chemotaxis GO:0006935 120 0.014
regulation of cellular amine metabolic process GO:0033238 0 0.014
negative regulation of signaling GO:0023057 61 0.014
nucleotide metabolic process GO:0009117 108 0.014
cellular amine metabolic process GO:0044106 15 0.014
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.014
taxis GO:0042330 128 0.014
gene silencing by rna GO:0031047 143 0.014
regulation of cellular ketone metabolic process GO:0010565 3 0.013
regulation of growth GO:0040008 409 0.013
regulation of cell communication GO:0010646 176 0.013
actomyosin structure organization GO:0031032 154 0.013
epithelial cell morphogenesis GO:0003382 2 0.013
cell cycle GO:0007049 526 0.012
regulation of multicellular organismal development GO:2000026 317 0.012
positive regulation of cell death GO:0010942 38 0.012
dosage compensation by hypoactivation of x chromosome GO:0042464 11 0.012
regulation of programmed cell death GO:0043067 50 0.012
male sex differentiation GO:0046661 86 0.012
regulation of post embryonic development GO:0048580 260 0.012
nematode male tail tip morphogenesis GO:0045138 77 0.012
oxoacid metabolic process GO:0043436 47 0.012
regulation of cell projection organization GO:0031344 38 0.012
organelle fission GO:0048285 363 0.012
peptidyl lysine acetylation GO:0018394 3 0.012
cellular response to abiotic stimulus GO:0071214 4 0.012
amine metabolic process GO:0009308 15 0.012
vulval development GO:0040025 333 0.012
positive regulation of innate immune response GO:0045089 4 0.012
organophosphate metabolic process GO:0019637 125 0.012
regulation of cellular component size GO:0032535 40 0.011
regulation of apoptotic process GO:0042981 36 0.011
phosphate containing compound metabolic process GO:0006796 232 0.011
myosin filament organization GO:0031033 138 0.011
regulation of transposition dna mediated GO:0000337 3 0.011
nucleobase containing small molecule metabolic process GO:0055086 115 0.011
nucleus organization GO:0006997 38 0.011
cellular response to topologically incorrect protein GO:0035967 76 0.011
positive regulation of cell projection organization GO:0031346 4 0.011
regulation of response to wounding GO:1903034 1 0.011
establishment of localization in cell GO:0051649 318 0.010
cellular macromolecule biosynthetic process GO:0034645 247 0.010
protein oligomerization GO:0051259 4 0.010
organic cyclic compound biosynthetic process GO:1901362 195 0.010
regulation of cell proliferation GO:0042127 105 0.010

lea-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.023
large intestine cancer DOID:5672 0 0.018
gastrointestinal system cancer DOID:3119 0 0.018
intestinal cancer DOID:10155 0 0.018
cancer DOID:162 0 0.018
organ system cancer DOID:0050686 0 0.018
colorectal cancer DOID:9256 0 0.018
disease of anatomical entity DOID:7 0 0.017