Caenorhabditis elegans

67 known processes

rde-1 (CELE_K08H10.7)

Protein RDE-1

rde-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.649
negative regulation of biological process GO:0048519 567 0.571
organelle organization GO:0006996 783 0.554
Fly
single organism reproductive process GO:0044702 1196 0.530
Zebrafish Fly
embryo development ending in birth or egg hatching GO:0009792 2992 0.519
locomotion GO:0040011 1634 0.469
establishment of localization GO:0051234 1171 0.307
reproductive structure development GO:0048608 850 0.293
genitalia development GO:0048806 741 0.245
regulation of biological quality GO:0065008 741 0.243
developmental process involved in reproduction GO:0003006 1165 0.237
Zebrafish Fly
establishment of localization in cell GO:0051649 318 0.224
sex differentiation GO:0007548 909 0.202
regulation of multicellular organismal development GO:2000026 317 0.199
Fly
negative regulation of metabolic process GO:0009892 240 0.182
cellular nitrogen compound biosynthetic process GO:0044271 192 0.176
Fly
nucleic acid templated transcription GO:0097659 169 0.159
Fly
regulation of metabolic process GO:0019222 478 0.158
development of primary sexual characteristics GO:0045137 840 0.156
cellular localization GO:0051641 360 0.141
Fly
organelle fission GO:0048285 363 0.140
Fly
vesicle mediated transport GO:0016192 852 0.138
single organism transport GO:0044765 447 0.138
negative regulation of gene expression GO:0010629 217 0.137
gene expression GO:0010467 412 0.135
transport GO:0006810 1093 0.125
single organism organelle organization GO:1902589 501 0.125
Fly
negative regulation of cellular process GO:0048523 239 0.122
Fly
gonad development GO:0008406 840 0.120
cell death GO:0008219 547 0.117
organic substance biosynthetic process GO:1901576 323 0.115
Fly
organ development GO:0048513 1102 0.115
hermaphrodite genitalia development GO:0040035 734 0.112
post embryonic development GO:0009791 2152 0.110
reproductive system development GO:0061458 850 0.107
regulation of growth GO:0040008 409 0.098
multicellular organismal aging GO:0010259 812 0.098
organic substance catabolic process GO:1901575 294 0.096
Fly
catabolic process GO:0009056 318 0.096
Fly
endocytosis GO:0006897 819 0.095
macromolecule localization GO:0033036 771 0.093
Fly
purine ribonucleoside metabolic process GO:0046128 92 0.092
endosomal transport GO:0016197 26 0.091
nucleoside phosphate catabolic process GO:1901292 77 0.091
aging GO:0007568 812 0.087
positive regulation of neurogenesis GO:0050769 4 0.085
nucleobase containing compound metabolic process GO:0006139 406 0.079
regulation of localization GO:0032879 194 0.078
Fly
anatomical structure homeostasis GO:0060249 11 0.078
nuclear migration GO:0007097 54 0.078
receptor mediated endocytosis GO:0006898 715 0.078
positive regulation of locomotion GO:0040017 42 0.077
meiotic chromosome segregation GO:0045132 139 0.075
lipid localization GO:0010876 573 0.075
single organism localization GO:1902578 518 0.073
Fly
secretion by cell GO:0032940 138 0.069
maintenance of location GO:0051235 580 0.068
rna interference GO:0016246 137 0.067
negative regulation of macromolecule metabolic process GO:0010605 229 0.066
signaling GO:0023052 401 0.065
lipid storage GO:0019915 565 0.064
death GO:0016265 547 0.064
intracellular signal transduction GO:0035556 96 0.063
cellular biosynthetic process GO:0044249 315 0.062
Fly
cellular macromolecular complex assembly GO:0034622 184 0.062
Fly
cellular component assembly involved in morphogenesis GO:0010927 183 0.059
Fly
lipid metabolic process GO:0006629 77 0.059
single organism signaling GO:0044700 401 0.058
signal transduction GO:0007165 317 0.056
determination of adult lifespan GO:0008340 812 0.056
gene silencing GO:0016458 143 0.056
cellular protein modification process GO:0006464 207 0.055
behavior GO:0007610 527 0.054
posttranscriptional gene silencing GO:0016441 143 0.054
protein localization GO:0008104 205 0.054
Fly
actin filament based process GO:0030029 191 0.054
organonitrogen compound metabolic process GO:1901564 151 0.053
regulation of multicellular organismal process GO:0051239 726 0.053
Fly
protein metabolic process GO:0019538 422 0.053
regulation of vesicle mediated transport GO:0060627 27 0.053
regulation of multi organism process GO:0043900 69 0.051
Fly
organic cyclic compound biosynthetic process GO:1901362 195 0.050
Fly
aromatic compound biosynthetic process GO:0019438 192 0.049
Fly
regulation of gene expression epigenetic GO:0040029 163 0.048
phagocytosis GO:0006909 115 0.047
negative regulation of developmental process GO:0051093 227 0.047
Fly
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.046
Fly
head development GO:0060322 1 0.046
phagocytosis engulfment GO:0006911 98 0.045
cellular component biogenesis GO:0044085 297 0.045
Fly
programmed cell death GO:0012501 500 0.044
regulation of gene expression GO:0010468 366 0.044
response to chemical GO:0042221 356 0.044
organophosphate catabolic process GO:0046434 81 0.043
response to external stimulus GO:0009605 289 0.043
Fly
membrane invagination GO:0010324 98 0.043
biosynthetic process GO:0009058 323 0.042
Fly
cellular catabolic process GO:0044248 199 0.042
Fly
regulation of phagocytosis engulfment GO:0060099 17 0.041
macromolecule biosynthetic process GO:0009059 250 0.041
Fly
cell type specific apoptotic process GO:0097285 4 0.040
positive regulation of developmental process GO:0051094 408 0.039
cellular protein metabolic process GO:0044267 279 0.038
glycosyl compound catabolic process GO:1901658 79 0.038
cellular macromolecule biosynthetic process GO:0034645 247 0.038
Fly
regulation of primary metabolic process GO:0080090 292 0.037
Fly
localization of cell GO:0051674 313 0.037
chromosome segregation GO:0007059 180 0.036
Fly
growth GO:0040007 562 0.036
cellular component assembly GO:0022607 293 0.036
Fly
regulation of rna biosynthetic process GO:2001141 165 0.036
Fly
myofibril assembly GO:0030239 154 0.036
organelle assembly GO:0070925 214 0.036
regulation of macromolecule metabolic process GO:0060255 421 0.036
regulation of developmental growth GO:0048638 389 0.036
gene silencing by rna GO:0031047 143 0.035
germ cell development GO:0007281 351 0.035
Zebrafish Fly
cellular response to stress GO:0033554 162 0.035
cytoskeleton organization GO:0007010 339 0.035
regulation of response to stimulus GO:0048583 243 0.034
Fly
purine nucleoside catabolic process GO:0006152 75 0.034
apoptotic process GO:0006915 478 0.034
single organism carbohydrate metabolic process GO:0044723 29 0.034
striated muscle myosin thick filament assembly GO:0071688 138 0.033
body morphogenesis GO:0010171 620 0.032
ribose phosphate metabolic process GO:0019693 99 0.032
regulation of rna metabolic process GO:0051252 173 0.032
Fly
engulfment of apoptotic cell GO:0043652 94 0.032
small molecule metabolic process GO:0044281 186 0.032
positive regulation of cell projection organization GO:0031346 4 0.032
phosphate containing compound metabolic process GO:0006796 232 0.032
posttranscriptional gene silencing by rna GO:0035194 143 0.031
regulation of cell development GO:0060284 49 0.031
Fly
female gamete generation GO:0007292 254 0.031
Fly
nucleoside phosphate metabolic process GO:0006753 108 0.031
purine nucleotide catabolic process GO:0006195 75 0.031
purine containing compound catabolic process GO:0072523 75 0.031
cellular protein complex assembly GO:0043623 178 0.031
regulation of endocytosis GO:0030100 25 0.030
regulation of multicellular organism growth GO:0040014 373 0.030
defense response GO:0006952 296 0.030
positive regulation of multicellular organismal process GO:0051240 417 0.030
multicellular organism growth GO:0035264 385 0.029
regulation of nitrogen compound metabolic process GO:0051171 222 0.029
Fly
myosin filament assembly GO:0031034 138 0.029
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.029
Fly
muscle cell development GO:0055001 158 0.029
nucleic acid metabolic process GO:0090304 299 0.029
response to biotic stimulus GO:0009607 101 0.028
Fly
regulation of cell migration GO:0030334 55 0.028
innate immune response GO:0045087 190 0.028
Fly
muscle cell differentiation GO:0042692 171 0.027
purine containing compound metabolic process GO:0072521 95 0.027
multicellular organism reproduction GO:0032504 819 0.027
Zebrafish Fly
regulation of phosphorus metabolic process GO:0051174 81 0.027
positive regulation of multicellular organism growth GO:0040018 352 0.027
carbohydrate derivative catabolic process GO:1901136 82 0.027
cell development GO:0048468 696 0.026
Zebrafish Fly
single organism catabolic process GO:0044712 129 0.026
purine nucleoside monophosphate catabolic process GO:0009128 28 0.026
positive regulation of developmental growth GO:0048639 354 0.026
gamete generation GO:0007276 461 0.026
Zebrafish Fly
secretion GO:0046903 147 0.025
regulation of post embryonic development GO:0048580 260 0.025
cell cell signaling GO:0007267 118 0.025
macromolecule catabolic process GO:0009057 202 0.025
Fly
cellular component morphogenesis GO:0032989 318 0.025
Fly
striated muscle cell development GO:0055002 157 0.025
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.024
Fly
response to other organism GO:0051707 101 0.024
Fly
ribonucleotide catabolic process GO:0009261 75 0.024
nucleoside triphosphate catabolic process GO:0009143 72 0.024
cell motility GO:0048870 313 0.024
regulation of neurogenesis GO:0050767 40 0.024
protein catabolic process GO:0030163 162 0.024
multicellular organismal reproductive behavior GO:0033057 384 0.024
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.024
Fly
neuron differentiation GO:0030182 217 0.023
actin cytoskeleton organization GO:0030036 184 0.023
response to wounding GO:0009611 4 0.023
protein complex biogenesis GO:0070271 186 0.023
regulation of cellular metabolic process GO:0031323 305 0.023
Fly
ribonucleoside catabolic process GO:0042454 77 0.023
nucleobase containing compound biosynthetic process GO:0034654 184 0.023
Fly
actomyosin structure organization GO:0031032 154 0.023
protein modification process GO:0036211 207 0.023
regulation of immune response GO:0050776 10 0.022
Fly
glycosyl compound metabolic process GO:1901657 100 0.022
negative regulation of nematode larval development GO:0061064 208 0.022
response to abiotic stimulus GO:0009628 152 0.022
transcription dna templated GO:0006351 168 0.021
Fly
synaptic transmission GO:0007268 106 0.021
organonitrogen compound catabolic process GO:1901565 90 0.021
neuromuscular junction development GO:0007528 2 0.021
regulation of biosynthetic process GO:0009889 189 0.021
Fly
defense response to bacterium GO:0042742 86 0.021
Fly
posttranscriptional regulation of gene expression GO:0010608 166 0.021
post embryonic organ development GO:0048569 336 0.020
purine nucleoside triphosphate catabolic process GO:0009146 72 0.020
muscle structure development GO:0061061 191 0.020
immune response GO:0006955 192 0.020
Fly
purine nucleoside monophosphate metabolic process GO:0009126 43 0.020
cell surface receptor signaling pathway GO:0007166 149 0.020
meiotic cell cycle process GO:1903046 170 0.020
organophosphate metabolic process GO:0019637 125 0.020
multicellular organismal reproductive process GO:0048609 815 0.020
Zebrafish Fly
cell migration GO:0016477 306 0.019
regulation of transport GO:0051049 91 0.019
cellular macromolecule localization GO:0070727 75 0.019
Fly
cellular response to dna damage stimulus GO:0006974 41 0.019
nucleotide catabolic process GO:0009166 77 0.019
multi multicellular organism process GO:0044706 390 0.019
ribonucleoside metabolic process GO:0009119 98 0.018
anatomical structure formation involved in morphogenesis GO:0048646 250 0.018
Fly
negative regulation of multicellular organismal process GO:0051241 236 0.018
cellular component movement GO:0006928 388 0.018
nucleoside metabolic process GO:0009116 99 0.018
nucleoside catabolic process GO:0009164 78 0.018
protein complex assembly GO:0006461 186 0.018
regulation of lipid biosynthetic process GO:0046890 1 0.018
vulval development GO:0040025 333 0.018
nucleoside triphosphate metabolic process GO:0009141 87 0.017
telomere organization GO:0032200 6 0.017
carbohydrate metabolic process GO:0005975 34 0.017
positive regulation of cell migration GO:0030335 3 0.017
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.017
single organism biosynthetic process GO:0044711 91 0.017
phosphorus metabolic process GO:0006793 232 0.017
positive regulation of catalytic activity GO:0043085 59 0.017
negative regulation of biosynthetic process GO:0009890 65 0.017
Fly
cellular response to organic substance GO:0071310 119 0.017
rna biosynthetic process GO:0032774 169 0.017
Fly
myosin filament organization GO:0031033 138 0.016
carbohydrate derivative metabolic process GO:1901135 141 0.016
regulation of developmental process GO:0050793 684 0.016
Fly
heterocycle biosynthetic process GO:0018130 187 0.016
Fly
negative regulation of vulval development GO:0040027 206 0.016
apoptotic cell clearance GO:0043277 111 0.016
oogenesis GO:0048477 229 0.016
Fly
single organism intracellular transport GO:1902582 70 0.015
negative regulation of cellular biosynthetic process GO:0031327 65 0.015
Fly
macromolecule modification GO:0043412 218 0.015
reproductive behavior GO:0019098 387 0.015
defense response to other organism GO:0098542 100 0.015
Fly
secondary metabolite biosynthetic process GO:0044550 3 0.015
positive regulation of growth GO:0045927 369 0.015
macromolecular complex subunit organization GO:0043933 320 0.015
Fly
ribonucleoside triphosphate catabolic process GO:0009203 72 0.015
organic substance transport GO:0071702 113 0.015
meiotic cell cycle GO:0051321 335 0.015
regulation of locomotion GO:0040012 161 0.015
negative regulation of cellular metabolic process GO:0031324 95 0.015
Fly
generation of neurons GO:0048699 235 0.015
adult locomotory behavior GO:0008344 1 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.014
positive regulation of transport GO:0051050 32 0.014
regulation of cellular catabolic process GO:0031329 51 0.014
Fly
membrane organization GO:0061024 135 0.014
regulation of macromolecule biosynthetic process GO:0010556 189 0.014
Fly
establishment of organelle localization GO:0051656 123 0.014
response to external biotic stimulus GO:0043207 101 0.014
Fly
regulation of cell differentiation GO:0045595 81 0.014
Fly
regulation of cellular component movement GO:0051270 62 0.014
regulation of programmed cell death GO:0043067 50 0.013
striated muscle cell differentiation GO:0051146 158 0.013
regulation of signal transduction GO:0009966 135 0.013
chondroitin sulfate proteoglycan metabolic process GO:0050654 4 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.013
Fly
phosphorylation GO:0016310 116 0.013
positive regulation of response to stimulus GO:0048584 55 0.013
Fly
ribonucleoside monophosphate metabolic process GO:0009161 45 0.013
regulation of cell motility GO:2000145 57 0.013
sexual reproduction GO:0019953 546 0.013
Zebrafish Fly
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.013
Fly
organelle localization GO:0051640 127 0.013
regulation of nucleic acid templated transcription GO:1903506 165 0.013
Fly
multi organism behavior GO:0051705 389 0.012
response to anesthetic GO:0072347 1 0.012
positive regulation of cell differentiation GO:0045597 8 0.012
macromolecular complex assembly GO:0065003 193 0.012
Fly
regulation of catalytic activity GO:0050790 78 0.012
negative regulation of nucleic acid templated transcription GO:1903507 53 0.012
Fly
regulation of cytoplasmic transport GO:1903649 3 0.012
mucopolysaccharide metabolic process GO:1903510 4 0.012
positive regulation of organ growth GO:0046622 4 0.012
regulation of nematode larval development GO:0061062 260 0.012
regulation of intracellular signal transduction GO:1902531 77 0.012
multi organism reproductive behavior GO:0044705 387 0.012
homeostatic process GO:0042592 51 0.012
taxis GO:0042330 128 0.012
negative regulation of post embryonic development GO:0048581 208 0.011
purine nucleoside metabolic process GO:0042278 92 0.011
regulation of phagocytosis GO:0050764 18 0.011
purine nucleoside triphosphate metabolic process GO:0009144 87 0.011
cytokinesis GO:0000910 80 0.011
regulation of molecular function GO:0065009 89 0.011
organonitrogen compound biosynthetic process GO:1901566 44 0.011
regulation of signaling GO:0023051 172 0.011
transcription from rna polymerase ii promoter GO:0006366 149 0.011
positive regulation of cellular process GO:0048522 332 0.011
Fly
multi organism reproductive process GO:0044703 867 0.011
Zebrafish Fly
ion transport GO:0006811 113 0.011
developmental growth GO:0048589 412 0.011
regulation of secretion GO:0051046 29 0.011
protein phosphorylation GO:0006468 85 0.011
autophagy GO:0006914 29 0.011
positive regulation of protein transport GO:0051222 4 0.011
golgi vesicle transport GO:0048193 3 0.011
response to bacterium GO:0009617 86 0.011
Fly
positive regulation of molecular function GO:0044093 61 0.010
purine nucleotide metabolic process GO:0006163 95 0.010
rna metabolic process GO:0016070 228 0.010
synaptic growth at neuromuscular junction GO:0051124 1 0.010
neuron apoptotic process GO:0051402 4 0.010
regulation of cell communication GO:0010646 176 0.010
single organism behavior GO:0044708 83 0.010
intracellular transport GO:0046907 77 0.010

rde-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.022
cancer DOID:162 0 0.015
organ system cancer DOID:0050686 0 0.011
gastrointestinal system cancer DOID:3119 0 0.011