Caenorhabditis elegans

67 known processes

lin-53 (CELE_K07A1.12)

Protein LIN-53

lin-53 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
developmental process involved in reproduction GO:0003006 1165 0.980
post embryonic development GO:0009791 2152 0.970
single organism reproductive process GO:0044702 1196 0.965
reproductive structure development GO:0048608 850 0.955
gonad development GO:0008406 840 0.954
genitalia development GO:0048806 741 0.954
hermaphrodite genitalia development GO:0040035 734 0.944
sex differentiation GO:0007548 909 0.917
reproductive system development GO:0061458 850 0.896
multicellular organism reproduction GO:0032504 819 0.885
locomotion GO:0040011 1634 0.825
Worm
organ development GO:0048513 1102 0.784
multicellular organismal reproductive process GO:0048609 815 0.781
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.777
embryo development ending in birth or egg hatching GO:0009792 2992 0.761
embryo development GO:0009790 3052 0.745
vulval development GO:0040025 333 0.728
germ cell development GO:0007281 351 0.726
oviposition GO:0018991 364 0.721
sexual reproduction GO:0019953 546 0.679
establishment of localization GO:0051234 1171 0.663
multicellular organismal reproductive behavior GO:0033057 384 0.638
meiotic chromosome segregation GO:0045132 139 0.621
multi organism reproductive process GO:0044703 867 0.611
vesicle mediated transport GO:0016192 852 0.609
transport GO:0006810 1093 0.601
negative regulation of macromolecule metabolic process GO:0010605 229 0.575
Mouse Worm Fly
positive regulation of nematode larval development GO:0061063 54 0.556
meiotic cell cycle GO:0051321 335 0.554
gamete generation GO:0007276 461 0.548
gene expression GO:0010467 412 0.536
Mouse Worm Fly
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.525
Mouse Fly
endocytosis GO:0006897 819 0.515
negative regulation of biological process GO:0048519 567 0.493
regulation of gene expression GO:0010468 366 0.480
Mouse Worm Fly
negative regulation of cellular process GO:0048523 239 0.480
Human Mouse Fly
meiotic cell cycle process GO:1903046 170 0.478
chromatin assembly or disassembly GO:0006333 1 0.475
Human Fly
development of primary sexual characteristics GO:0045137 840 0.471
negative regulation of vulval development GO:0040027 206 0.470
multi multicellular organism process GO:0044706 390 0.467
transcription from rna polymerase ii promoter GO:0006366 149 0.466
Mouse Fly
cellular macromolecule biosynthetic process GO:0034645 247 0.456
Mouse Fly
regulation of nitrogen compound metabolic process GO:0051171 222 0.437
Mouse Fly
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.433
Mouse Fly
protein metabolic process GO:0019538 422 0.426
Fly
cellular biosynthetic process GO:0044249 315 0.426
Mouse Fly
female gamete generation GO:0007292 254 0.421
negative regulation of cellular metabolic process GO:0031324 95 0.421
Mouse Fly
rna metabolic process GO:0016070 228 0.418
Mouse Fly
regulation of macromolecule biosynthetic process GO:0010556 189 0.411
Mouse Fly
organelle organization GO:0006996 783 0.401
Human Fly
post embryonic organ development GO:0048569 336 0.401
negative regulation of multicellular organismal process GO:0051241 236 0.399
regulation of vulval development GO:0040028 248 0.389
oogenesis GO:0048477 229 0.386
negative regulation of cellular biosynthetic process GO:0031327 65 0.383
Mouse Fly
meiotic nuclear division GO:0007126 300 0.376
chromosome organization GO:0051276 104 0.374
Human Fly
regulation of rna biosynthetic process GO:2001141 165 0.371
Mouse Fly
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.365
Mouse Fly
multi organism reproductive behavior GO:0044705 387 0.359
negative regulation of metabolic process GO:0009892 240 0.338
Mouse Worm Fly
body morphogenesis GO:0010171 620 0.332
regulation of transcription dna templated GO:0006355 164 0.327
Mouse Fly
negative regulation of biosynthetic process GO:0009890 65 0.326
Mouse Fly
negative regulation of gene expression GO:0010629 217 0.319
Mouse Worm Fly
nucleic acid templated transcription GO:0097659 169 0.308
Mouse Fly
death GO:0016265 547 0.296
behavior GO:0007610 527 0.293
cellular protein modification process GO:0006464 207 0.288
Fly
negative regulation of nematode larval development GO:0061064 208 0.288
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.285
Mouse Fly
cell cycle GO:0007049 526 0.283
Fly
receptor mediated endocytosis GO:0006898 715 0.277
head development GO:0060322 1 0.271
regulation of cellular metabolic process GO:0031323 305 0.271
Mouse Fly
growth GO:0040007 562 0.257
Human Zebrafish
nucleic acid metabolic process GO:0090304 299 0.256
Human Mouse Fly
regulation of macromolecule metabolic process GO:0060255 421 0.254
Mouse Worm Fly
reproductive behavior GO:0019098 387 0.254
multicellular organismal aging GO:0010259 812 0.252
transcription dna templated GO:0006351 168 0.250
Mouse Fly
cellular component biogenesis GO:0044085 297 0.247
Human Fly
mitotic cell cycle process GO:1903047 194 0.240
Fly
aging GO:0007568 812 0.237
cell development GO:0048468 696 0.231
Fly
cell proliferation GO:0008283 116 0.230
Fly
cell death GO:0008219 547 0.230
cell cycle process GO:0022402 482 0.229
Fly
multi organism behavior GO:0051705 389 0.227
programmed cell death GO:0012501 500 0.227
negative regulation of rna biosynthetic process GO:1902679 53 0.225
Mouse Fly
macromolecule biosynthetic process GO:0009059 250 0.221
Mouse Fly
rna biosynthetic process GO:0032774 169 0.220
Mouse Fly
digestive tract development GO:0048565 122 0.218
determination of adult lifespan GO:0008340 812 0.217
macromolecular complex subunit organization GO:0043933 320 0.215
Human Fly
cellular localization GO:0051641 360 0.214
negative regulation of transcription dna templated GO:0045892 53 0.213
Mouse Fly
organic cyclic compound biosynthetic process GO:1901362 195 0.213
Mouse Fly
apoptotic process GO:0006915 478 0.212
positive regulation of vulval development GO:0040026 52 0.206
single organism localization GO:1902578 518 0.199
regulation of nucleic acid templated transcription GO:1903506 165 0.199
Mouse Fly
single organism transport GO:0044765 447 0.199
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.197
Mouse Fly
cellular protein metabolic process GO:0044267 279 0.196
Fly
mitotic spindle organization GO:0007052 81 0.195
negative regulation of rna metabolic process GO:0051253 53 0.193
Mouse Fly
establishment of localization in cell GO:0051649 318 0.193
biosynthetic process GO:0009058 323 0.188
Mouse Fly
response to chemical GO:0042221 356 0.184
Rat
regulation of cellular biosynthetic process GO:0031326 189 0.184
Mouse Fly
macromolecule modification GO:0043412 218 0.179
Fly
localization of cell GO:0051674 313 0.178
regulation of meiotic cell cycle GO:0051445 136 0.177
cell migration GO:0016477 306 0.172
organelle fission GO:0048285 363 0.172
heterocycle biosynthetic process GO:0018130 187 0.171
Mouse Fly
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.168
Mouse Fly
regulation of nematode larval development GO:0061062 260 0.166
regulation of rna metabolic process GO:0051252 173 0.164
Mouse Fly
regulation of biosynthetic process GO:0009889 189 0.161
Mouse Fly
cellular component morphogenesis GO:0032989 318 0.159
Fly
macromolecular complex assembly GO:0065003 193 0.155
Human Fly
neurogenesis GO:0022008 236 0.151
Fly
generation of neurons GO:0048699 235 0.150
Fly
negative regulation of developmental process GO:0051093 227 0.145
positive regulation of macromolecule metabolic process GO:0010604 149 0.142
response to external stimulus GO:0009605 289 0.141
negative regulation of gene expression epigenetic GO:0045814 2 0.140
Fly
regulation of primary metabolic process GO:0080090 292 0.139
Mouse Fly
rrna metabolic process GO:0016072 3 0.138
macromolecule catabolic process GO:0009057 202 0.136
regulation of gene expression epigenetic GO:0040029 163 0.135
Worm Fly
cell division GO:0051301 262 0.135
Fly
macromolecule localization GO:0033036 771 0.131
single organism signaling GO:0044700 401 0.129
chromosome segregation GO:0007059 180 0.128
organic substance catabolic process GO:1901575 294 0.126
Human
organ morphogenesis GO:0009887 67 0.126
taxis GO:0042330 128 0.126
protein complex subunit organization GO:0071822 280 0.124
Human Fly
regulation of multicellular organismal process GO:0051239 726 0.124
posttranscriptional regulation of gene expression GO:0010608 166 0.123
Worm
negative regulation of nucleic acid templated transcription GO:1903507 53 0.119
Mouse Fly
embryonic morphogenesis GO:0048598 152 0.117
regulation of protein metabolic process GO:0051246 81 0.117
developmental growth GO:0048589 412 0.115
Zebrafish
positive regulation of nucleic acid templated transcription GO:1903508 102 0.114
mitotic nuclear division GO:0007067 89 0.112
protein catabolic process GO:0030163 162 0.110
cytoskeleton organization GO:0007010 339 0.110
sensory organ morphogenesis GO:0090596 2 0.108
regulation of growth GO:0040008 409 0.107
Human
system process GO:0003008 136 0.107
dna conformation change GO:0071103 11 0.106
Human Fly
protein complex assembly GO:0006461 186 0.102
Human Fly
microtubule based process GO:0007017 182 0.101
epithelium development GO:0060429 68 0.100
nucleobase containing compound metabolic process GO:0006139 406 0.099
Human Mouse Fly
protein localization GO:0008104 205 0.098
cellular component assembly GO:0022607 293 0.097
Human Fly
organelle assembly GO:0070925 214 0.096
neuron projection guidance GO:0097485 82 0.096
negative regulation of post embryonic development GO:0048581 208 0.096
regulation of response to stimulus GO:0048583 243 0.095
regulation of metabolic process GO:0019222 478 0.092
Mouse Worm Fly
mapk cascade GO:0000165 31 0.092
regulation of cell proliferation GO:0042127 105 0.091
Fly
regulation of developmental process GO:0050793 684 0.090
tissue development GO:0009888 112 0.089
Zebrafish
regulation of cell communication GO:0010646 176 0.088
phosphorylation GO:0016310 116 0.088
cell motility GO:0048870 313 0.087
regulation of post embryonic development GO:0048580 260 0.087
positive regulation of jnk cascade GO:0046330 3 0.087
regulation of multicellular organismal development GO:2000026 317 0.087
cellular component movement GO:0006928 388 0.085
response to wounding GO:0009611 4 0.085
Zebrafish
positive regulation of post embryonic development GO:0048582 54 0.084
signaling GO:0023052 401 0.082
regulation of biological quality GO:0065008 741 0.082
multicellular organism growth GO:0035264 385 0.081
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.079
Mouse Fly
intracellular signal transduction GO:0035556 96 0.078
positive regulation of catalytic activity GO:0043085 59 0.078
regulation of developmental growth GO:0048638 389 0.078
regulation of multicellular organism growth GO:0040014 373 0.077
cellular catabolic process GO:0044248 199 0.076
Human
aromatic compound biosynthetic process GO:0019438 192 0.074
Mouse Fly
immune response GO:0006955 192 0.074
tube development GO:0035295 126 0.073
single organism organelle organization GO:1902589 501 0.072
Fly
positive regulation of cellular process GO:0048522 332 0.072
Fly
regulation of signal transduction GO:0009966 135 0.070
gene silencing GO:0016458 143 0.070
Worm Fly
positive regulation of gene expression GO:0010628 112 0.070
cell surface receptor signaling pathway GO:0007166 149 0.068
response to organic substance GO:0010033 131 0.068
Rat
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.067
cellular macromolecular complex assembly GO:0034622 184 0.066
Human Fly
oocyte differentiation GO:0009994 45 0.066
embryonic pattern specification GO:0009880 21 0.066
protein modification process GO:0036211 207 0.064
Fly
dna packaging GO:0006323 7 0.064
Human Fly
regulation of cell division GO:0051302 142 0.064
positive regulation of protein kinase activity GO:0045860 18 0.063
regulation of signaling GO:0023051 172 0.063
organic cyclic compound catabolic process GO:1901361 119 0.062
Human
positive regulation of signaling GO:0023056 66 0.062
anatomical structure formation involved in morphogenesis GO:0048646 250 0.062
establishment of organelle localization GO:0051656 123 0.061
aromatic compound catabolic process GO:0019439 116 0.061
Human
regulation of cellular component organization GO:0051128 248 0.060
Human
nucleobase containing compound biosynthetic process GO:0034654 184 0.058
Mouse Fly
maintenance of location GO:0051235 580 0.057
positive regulation of developmental growth GO:0048639 354 0.057
digestive system development GO:0055123 122 0.057
positive regulation of developmental process GO:0051094 408 0.056
chromatin remodeling GO:0006338 2 0.055
Human Fly
response to external biotic stimulus GO:0043207 101 0.055
lipid storage GO:0019915 565 0.055
cellular protein complex assembly GO:0043623 178 0.055
homeostatic process GO:0042592 51 0.054
ras protein signal transduction GO:0007265 31 0.054
ribosome biogenesis GO:0042254 4 0.054
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.054
Mouse Fly
protein complex biogenesis GO:0070271 186 0.053
Human Fly
positive regulation of signal transduction GO:0009967 40 0.053
signal transduction GO:0007165 317 0.052
cell part morphogenesis GO:0032990 152 0.051
Fly
regulation of phosphorus metabolic process GO:0051174 81 0.051
organic substance biosynthetic process GO:1901576 323 0.050
Mouse Fly
cell morphogenesis GO:0000902 163 0.050
Fly
purine nucleoside triphosphate metabolic process GO:0009144 87 0.049
Human
regulation of localization GO:0032879 194 0.048
cellular nitrogen compound biosynthetic process GO:0044271 192 0.048
Mouse Fly
positive regulation of neurogenesis GO:0050769 4 0.048
regulation of molecular function GO:0065009 89 0.047
neuron differentiation GO:0030182 217 0.047
Fly
cell fate commitment GO:0045165 139 0.047
lipid localization GO:0010876 573 0.046
protein phosphorylation GO:0006468 85 0.046
cellular response to stress GO:0033554 162 0.045
Human
cellular response to chemical stimulus GO:0070887 129 0.045
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.045
positive regulation of transferase activity GO:0051347 21 0.045
positive regulation of molecular function GO:0044093 61 0.044
positive regulation of protein metabolic process GO:0051247 45 0.044
dna metabolic process GO:0006259 74 0.044
Human Fly
regulation of meiosis GO:0040020 94 0.044
establishment or maintenance of cell polarity GO:0007163 63 0.044
chemotaxis GO:0006935 120 0.044
chromatin organization GO:0006325 32 0.043
Human Fly
defense response GO:0006952 296 0.042
nervous system development GO:0007399 253 0.042
Fly
response to abiotic stimulus GO:0009628 152 0.042
Human
protein dna complex subunit organization GO:0071824 7 0.041
Human Fly
nucleobase containing compound catabolic process GO:0034655 114 0.040
Human
neural precursor cell proliferation GO:0061351 9 0.040
posttranscriptional gene silencing by rna GO:0035194 143 0.040
Worm
positive regulation of cellular metabolic process GO:0031325 178 0.039
intracellular receptor signaling pathway GO:0030522 2 0.039
negative regulation of chromosome segregation GO:0051985 4 0.039
negative regulation of signaling GO:0023057 61 0.039
rna interference GO:0016246 137 0.038
Worm
protein dna complex assembly GO:0065004 7 0.038
Human Fly
pattern specification process GO:0007389 59 0.038
Fly
cellular macromolecule localization GO:0070727 75 0.038
gene silencing by rna GO:0031047 143 0.038
Worm
muscle structure development GO:0061061 191 0.037
Fly
regionalization GO:0003002 31 0.037
Fly
positive regulation of multicellular organism growth GO:0040018 352 0.037
regulation of locomotion GO:0040012 161 0.037
heterocycle catabolic process GO:0046700 119 0.036
Human
signal transduction by phosphorylation GO:0023014 31 0.036
regulation of cell differentiation GO:0045595 81 0.036
positive regulation of growth GO:0045927 369 0.036
membrane organization GO:0061024 135 0.035
regulation of organelle organization GO:0033043 164 0.035
single organism cellular localization GO:1902580 72 0.034
actin cytoskeleton organization GO:0030036 184 0.034
oocyte development GO:0048599 44 0.034
single organism behavior GO:0044708 83 0.034
digestive tract morphogenesis GO:0048546 76 0.034
striated muscle cell differentiation GO:0051146 158 0.033
regulation of intracellular signal transduction GO:1902531 77 0.033
small molecule metabolic process GO:0044281 186 0.033
Human
spermatogenesis GO:0007283 41 0.032
regeneration GO:0031099 4 0.032
Zebrafish
apoptotic cell clearance GO:0043277 111 0.032
pronuclear migration GO:0035046 51 0.032
regulation of cell cycle process GO:0010564 145 0.032
single organism biosynthetic process GO:0044711 91 0.032
positive regulation of intracellular signal transduction GO:1902533 24 0.032
axonogenesis GO:0007409 102 0.032
proximal distal axis specification GO:0009946 6 0.032
negative regulation of response to stimulus GO:0048585 73 0.031
regulation of stem cell differentiation GO:2000736 1 0.031
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.030
Fly
filopodium assembly GO:0046847 2 0.030
catabolic process GO:0009056 318 0.029
Human
positive regulation of metabolic process GO:0009893 187 0.029
regulation of cellular protein metabolic process GO:0032268 75 0.029
posttranscriptional gene silencing GO:0016441 143 0.028
Worm
molting cycle GO:0042303 281 0.028
cellular nitrogen compound catabolic process GO:0044270 119 0.028
Human
engulfment of apoptotic cell GO:0043652 94 0.028
positive regulation of multicellular organismal process GO:0051240 417 0.027
positive regulation of kinase activity GO:0033674 19 0.027
male gamete generation GO:0048232 41 0.027
cell projection morphogenesis GO:0048858 148 0.027
Fly
female meiotic division GO:0007143 17 0.027
muscle cell development GO:0055001 158 0.027
cell projection organization GO:0030030 231 0.027
Fly
tube morphogenesis GO:0035239 79 0.026
chromatin modification GO:0016568 32 0.026
Human Fly
axon guidance GO:0007411 82 0.026
phagocytosis GO:0006909 115 0.026
cognition GO:0050890 27 0.026
actin filament based process GO:0030029 191 0.026
regulation of cell motility GO:2000145 57 0.026
negative regulation of neurogenesis GO:0050768 4 0.025
response to other organism GO:0051707 101 0.025
axon development GO:0061564 163 0.025
proteolysis GO:0006508 61 0.025
segmentation GO:0035282 7 0.025
Fly
adult behavior GO:0030534 3 0.025
neuron projection morphogenesis GO:0048812 114 0.025
Fly
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.024
positive regulation of mapk cascade GO:0043410 14 0.024
regulation of filopodium assembly GO:0051489 2 0.024
protein polymerization GO:0051258 26 0.024
organic acid metabolic process GO:0006082 47 0.023
regulation of kinase activity GO:0043549 29 0.023
single fertilization GO:0007338 61 0.023
fertilization GO:0009566 63 0.023
positive regulation of response to stimulus GO:0048584 55 0.023
cellular protein catabolic process GO:0044257 37 0.023
actomyosin structure organization GO:0031032 154 0.023
organonitrogen compound metabolic process GO:1901564 151 0.022
Human
secretion GO:0046903 147 0.022
secretion by cell GO:0032940 138 0.022
intracellular transport GO:0046907 77 0.022
phagocytosis engulfment GO:0006911 98 0.022
dauer larval development GO:0040024 92 0.022
regulation of cell cycle GO:0051726 194 0.022
Fly
regulation of mapk cascade GO:0043408 23 0.022
cellular response to organic substance GO:0071310 119 0.022
regulation of mitotic cell cycle GO:0007346 76 0.022
Fly
carboxylic acid metabolic process GO:0019752 34 0.021
positive regulation of rna metabolic process GO:0051254 103 0.021
protein modification by small protein conjugation or removal GO:0070647 40 0.021
cellular protein localization GO:0034613 75 0.021
modification dependent macromolecule catabolic process GO:0043632 32 0.021
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.021
single organism intracellular transport GO:1902582 70 0.021
ubiquitin dependent protein catabolic process GO:0006511 32 0.021
regulation of jun kinase activity GO:0043506 3 0.021
regulation of mitosis GO:0007088 18 0.020
regulation of cellular ketone metabolic process GO:0010565 3 0.019
oxoacid metabolic process GO:0043436 47 0.019
establishment of cell polarity GO:0030010 46 0.019
muscle cell differentiation GO:0042692 171 0.019
male sex differentiation GO:0046661 86 0.019
inductive cell migration GO:0040039 145 0.019
regulation of protein serine threonine kinase activity GO:0071900 18 0.019
regulation of cytoskeleton organization GO:0051493 41 0.019
response to biotic stimulus GO:0009607 101 0.018
adult locomotory behavior GO:0008344 1 0.018
regulation of catalytic activity GO:0050790 78 0.018
positive regulation of transcription dna templated GO:0045893 102 0.018
positive regulation of cell communication GO:0010647 69 0.018
positive regulation of meiotic cell cycle GO:0051446 47 0.018
cytokinesis GO:0000910 80 0.018
Fly
positive regulation of phosphorus metabolic process GO:0010562 56 0.018
regulation of phosphorylation GO:0042325 45 0.018
oocyte axis specification GO:0007309 2 0.017
phosphate containing compound metabolic process GO:0006796 232 0.017
Human
regulation of nuclear division GO:0051783 115 0.017
neuron projection development GO:0031175 187 0.017
Fly
wnt signaling pathway GO:0016055 27 0.017
organelle localization GO:0051640 127 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
regulation of cellular amine metabolic process GO:0033238 0 0.017
cellular ketone metabolic process GO:0042180 14 0.016
rna processing GO:0006396 34 0.016
membrane invagination GO:0010324 98 0.016
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 4 0.016
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.016
negative regulation of cell communication GO:0010648 61 0.016
neuron recognition GO:0008038 83 0.016
modification dependent protein catabolic process GO:0019941 32 0.016
neurological system process GO:0050877 53 0.016
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.016
cellular macromolecule catabolic process GO:0044265 73 0.016
small gtpase mediated signal transduction GO:0007264 32 0.016
establishment of spindle orientation GO:0051294 34 0.016
cell growth GO:0016049 44 0.016
Human
regulation of sister chromatid cohesion GO:0007063 1 0.015
protein modification by small protein conjugation GO:0032446 31 0.015
cellular amino acid metabolic process GO:0006520 15 0.015
establishment of mitotic spindle orientation GO:0000132 28 0.015
organic substance transport GO:0071702 113 0.015
regulation of transferase activity GO:0051338 31 0.015
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 2 0.015
response to temperature stimulus GO:0009266 66 0.014
Human
positive regulation of phosphorylation GO:0042327 27 0.014
cellular response to abiotic stimulus GO:0071214 4 0.014
positive regulation of rna biosynthetic process GO:1902680 102 0.014
regulation of protein kinase activity GO:0045859 28 0.014
collagen and cuticulin based cuticle development GO:0040002 99 0.014
positive regulation of protein serine threonine kinase activity GO:0071902 12 0.014
protein localization to organelle GO:0033365 37 0.014
transcription elongation from rna polymerase ii promoter GO:0006368 1 0.014
g1 s transition of mitotic cell cycle GO:0000082 2 0.013
regulation of synapse assembly GO:0051963 2 0.013
regulation of cell development GO:0060284 49 0.013
regulation of anatomical structure size GO:0090066 46 0.013
dna templated transcription elongation GO:0006354 1 0.013
response to inorganic substance GO:0010035 50 0.013
myosin filament organization GO:0031033 138 0.013
peptidyl amino acid modification GO:0018193 58 0.013
Fly
meiotic cytokinesis GO:0033206 15 0.013
nucleus localization GO:0051647 55 0.013
phosphorus metabolic process GO:0006793 232 0.013
Human
neuron development GO:0048666 199 0.013
Fly
cellular response to endogenous stimulus GO:0071495 32 0.013
protein oligomerization GO:0051259 4 0.013
oocyte construction GO:0007308 2 0.013
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 4 0.013
response to oxygen containing compound GO:1901700 44 0.013
purine nucleoside catabolic process GO:0006152 75 0.013
Human
detection of external stimulus GO:0009581 4 0.013
amine metabolic process GO:0009308 15 0.013
positive regulation of cellular biosynthetic process GO:0031328 109 0.013
transmembrane transport GO:0055085 110 0.012
establishment of nucleus localization GO:0040023 55 0.012
innate immune response GO:0045087 190 0.012
negative regulation of mitotic cell cycle GO:0045930 42 0.012
regulation of actin filament based process GO:0032970 22 0.012
positive regulation of protein modification process GO:0031401 29 0.012
cell cycle switching mitotic to meiotic cell cycle GO:0051728 35 0.012
regulation of protein modification process GO:0031399 46 0.012
organonitrogen compound catabolic process GO:1901565 90 0.012
Human
epidermis development GO:0008544 24 0.012
axonal fasciculation GO:0007413 79 0.012
cellular component assembly involved in morphogenesis GO:0010927 183 0.012
olfactory behavior GO:0042048 27 0.012
cellular amine metabolic process GO:0044106 15 0.012
peptidyl tyrosine phosphorylation GO:0018108 2 0.012
regulation of protein localization GO:0032880 50 0.012
cuticle development GO:0042335 100 0.012
regulation of apoptotic signaling pathway GO:2001233 1 0.012
embryonic body morphogenesis GO:0010172 49 0.011
regulation of cellular component size GO:0032535 40 0.011
tissue morphogenesis GO:0048729 65 0.011
purine ribonucleotide metabolic process GO:0009150 95 0.011
Human
synaptic growth at neuromuscular junction GO:0051124 1 0.011
sister chromatid segregation GO:0000819 46 0.011
regulation of phosphate metabolic process GO:0019220 81 0.011
mitotic g2 m transition checkpoint GO:0044818 1 0.011
neuromuscular junction development GO:0007528 2 0.011
regulation of dna replication GO:0006275 5 0.011
stem cell proliferation GO:0072089 9 0.011
oxidation reduction process GO:0055114 59 0.011
nematode male tail tip morphogenesis GO:0045138 77 0.011
negative regulation of cellular protein catabolic process GO:1903363 4 0.011
covalent chromatin modification GO:0016569 30 0.011
Fly
cell cycle g1 s phase transition GO:0044843 2 0.010
regulation of protein ubiquitination GO:0031396 3 0.010
germline cell cycle switching mitotic to meiotic cell cycle GO:0051729 35 0.010
positive regulation of cellular component organization GO:0051130 34 0.010
regulation of protein stability GO:0031647 3 0.010
regulation of protein targeting GO:1903533 3 0.010
positive regulation of cell migration GO:0030335 3 0.010
striated muscle cell development GO:0055002 157 0.010
cell cell signaling GO:0007267 118 0.010
cellular response to growth factor stimulus GO:0071363 18 0.010

lin-53 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
nervous system disease DOID:863 0 0.013