Caenorhabditis elegans

10 known processes

mak-2 (CELE_C44C8.6)

Protein MAK-2

mak-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2152 0.284
embryo development GO:0009790 3052 0.229
Zebrafish Worm
receptor mediated endocytosis GO:0006898 715 0.117
regulation of biological quality GO:0065008 741 0.112
Human Mouse Fly
embryo development ending in birth or egg hatching GO:0009792 2992 0.112
Worm
programmed cell death GO:0012501 500 0.109
multicellular organismal reproductive process GO:0048609 815 0.102
locomotion GO:0040011 1634 0.098
signaling GO:0023052 401 0.097
Human Mouse Fly
organ development GO:0048513 1102 0.095
Mouse
cell morphogenesis GO:0000902 163 0.095
Fly
chromosome organization GO:0051276 104 0.095
endocytosis GO:0006897 819 0.090
Mouse
multicellular organismal aging GO:0010259 812 0.085
negative regulation of biological process GO:0048519 567 0.078
transport GO:0006810 1093 0.077
Mouse
macromolecule catabolic process GO:0009057 202 0.076
cellular component movement GO:0006928 388 0.072
immune response GO:0006955 192 0.068
Mouse
regulation of multicellular organismal process GO:0051239 726 0.066
Human Mouse
macromolecule localization GO:0033036 771 0.065
organelle organization GO:0006996 783 0.065
organic substance catabolic process GO:1901575 294 0.064
cell cycle process GO:0022402 482 0.064
Human
organelle fission GO:0048285 363 0.062
meiotic cell cycle GO:0051321 335 0.062
establishment of localization GO:0051234 1171 0.061
Mouse
gamete generation GO:0007276 461 0.061
regulation of developmental process GO:0050793 684 0.060
Fly
oviposition GO:0018991 364 0.060
lipid localization GO:0010876 573 0.058
lipid storage GO:0019915 565 0.057
maintenance of location GO:0051235 580 0.057
cell death GO:0008219 547 0.051
protein catabolic process GO:0030163 162 0.051
cell cycle GO:0007049 526 0.050
Human
single organism reproductive process GO:0044702 1196 0.050
defense response GO:0006952 296 0.049
Mouse
reproductive behavior GO:0019098 387 0.049
meiotic nuclear division GO:0007126 300 0.049
multi organism reproductive process GO:0044703 867 0.048
regulation of growth GO:0040008 409 0.048
multi multicellular organism process GO:0044706 390 0.047
response to external stimulus GO:0009605 289 0.047
Mouse
determination of adult lifespan GO:0008340 812 0.047
behavior GO:0007610 527 0.047
growth GO:0040007 562 0.045
multicellular organism reproduction GO:0032504 819 0.045
phosphate containing compound metabolic process GO:0006796 232 0.044
Human Zebrafish Mouse Fly
dna metabolic process GO:0006259 74 0.044
neuron differentiation GO:0030182 217 0.044
vesicle mediated transport GO:0016192 852 0.042
Mouse
multi organism reproductive behavior GO:0044705 387 0.042
molting cycle GO:0042303 281 0.042
protein metabolic process GO:0019538 422 0.041
Human Mouse
aging GO:0007568 812 0.041
response to chemical GO:0042221 356 0.041
Human Mouse
cell projection morphogenesis GO:0048858 148 0.040
cellular component morphogenesis GO:0032989 318 0.040
Fly
cell development GO:0048468 696 0.039
body morphogenesis GO:0010171 620 0.039
regulation of signal transduction GO:0009966 135 0.038
Fly
multicellular organismal reproductive behavior GO:0033057 384 0.038
localization of cell GO:0051674 313 0.038
neurogenesis GO:0022008 236 0.038
establishment of spindle localization GO:0051293 51 0.037
apoptotic process GO:0006915 478 0.037
multi organism behavior GO:0051705 389 0.037
head development GO:0060322 1 0.037
sex differentiation GO:0007548 909 0.037
death GO:0016265 547 0.037
heterocycle biosynthetic process GO:0018130 187 0.034
gene expression GO:0010467 412 0.034
Human Mouse
sexual reproduction GO:0019953 546 0.033
regulation of developmental growth GO:0048638 389 0.033
negative regulation of developmental process GO:0051093 227 0.032
cell migration GO:0016477 306 0.031
axon development GO:0061564 163 0.031
regulation of macromolecule metabolic process GO:0060255 421 0.030
Human Mouse
protein localization GO:0008104 205 0.029
taxis GO:0042330 128 0.028
nervous system development GO:0007399 253 0.028
innate immune response GO:0045087 190 0.027
Mouse
positive regulation of developmental process GO:0051094 408 0.026
positive regulation of response to stimulus GO:0048584 55 0.025
Mouse
spindle localization GO:0051653 51 0.025
organelle assembly GO:0070925 214 0.025
protein modification process GO:0036211 207 0.023
Human Mouse
cytoskeleton organization GO:0007010 339 0.023
regulation of cell cycle GO:0051726 194 0.023
positive regulation of multicellular organismal process GO:0051240 417 0.023
developmental growth GO:0048589 412 0.023
single organism signaling GO:0044700 401 0.023
Human Mouse Fly
cell part morphogenesis GO:0032990 152 0.023
posttranscriptional regulation of gene expression GO:0010608 166 0.023
Human Mouse
positive regulation of growth GO:0045927 369 0.023
nucleobase containing compound metabolic process GO:0006139 406 0.023
regulation of reproductive process GO:2000241 66 0.023
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.022
chromosome segregation GO:0007059 180 0.022
cellular protein metabolic process GO:0044267 279 0.022
Human Mouse
genitalia development GO:0048806 741 0.022
posttranscriptional gene silencing by rna GO:0035194 143 0.022
regulation of oviposition GO:0046662 43 0.022
single organism organelle organization GO:1902589 501 0.022
regulation of cellular component organization GO:0051128 248 0.022
Fly
negative regulation of multicellular organismal process GO:0051241 236 0.022
multicellular organism growth GO:0035264 385 0.021
skeletal muscle organ development GO:0060538 3 0.021
response to abiotic stimulus GO:0009628 152 0.021
Fly
regulation of cellular ketone metabolic process GO:0010565 3 0.021
reproductive system development GO:0061458 850 0.021
organic substance biosynthetic process GO:1901576 323 0.021
nucleic acid metabolic process GO:0090304 299 0.021
hermaphrodite genitalia development GO:0040035 734 0.021
generation of neurons GO:0048699 235 0.021
mesodermal cell migration GO:0008078 9 0.021
cell motility GO:0048870 313 0.020
positive regulation of cellular metabolic process GO:0031325 178 0.020
cellular macromolecule biosynthetic process GO:0034645 247 0.020
regulation of cell cycle process GO:0010564 145 0.020
regulation of behavior GO:0050795 97 0.019
regeneration GO:0031099 4 0.019
regulation of multicellular organismal development GO:2000026 317 0.019
neuromuscular junction development GO:0007528 2 0.019
regulation of cell motility GO:2000145 57 0.019
cellular component assembly GO:0022607 293 0.019
response to endoplasmic reticulum stress GO:0034976 71 0.019
oxoacid metabolic process GO:0043436 47 0.019
regulation of multicellular organism growth GO:0040014 373 0.019
muscle tissue development GO:0060537 1 0.018
positive regulation of developmental growth GO:0048639 354 0.018
regulation of nuclear division GO:0051783 115 0.018
neurological system process GO:0050877 53 0.018
regulation of anatomical structure morphogenesis GO:0022603 51 0.018
Fly
tube development GO:0035295 126 0.018
Zebrafish
neuron projection morphogenesis GO:0048812 114 0.018
developmental process involved in reproduction GO:0003006 1165 0.018
vulval development GO:0040025 333 0.018
response to wounding GO:0009611 4 0.017
regulation of cell division GO:0051302 142 0.017
regulation of organelle organization GO:0033043 164 0.017
cellular protein modification process GO:0006464 207 0.017
Human Mouse
regulation of cellular amine metabolic process GO:0033238 0 0.017
cell morphogenesis involved in differentiation GO:0000904 112 0.017
regulation of cell communication GO:0010646 176 0.017
Fly
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.017
response to bacterium GO:0009617 86 0.017
Mouse
spindle organization GO:0007051 92 0.017
nucleotide metabolic process GO:0009117 108 0.017
cellular response to stress GO:0033554 162 0.017
Human Fly
negative regulation of vulval development GO:0040027 206 0.016
intracellular signal transduction GO:0035556 96 0.016
Fly
negative regulation of post embryonic development GO:0048581 208 0.016
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.016
tissue development GO:0009888 112 0.016
Zebrafish
regulation of meiosis GO:0040020 94 0.016
reproductive structure development GO:0048608 850 0.016
negative regulation of gene expression GO:0010629 217 0.016
system process GO:0003008 136 0.016
macromolecule modification GO:0043412 218 0.016
Human Mouse
response to external biotic stimulus GO:0043207 101 0.016
Mouse
response to topologically incorrect protein GO:0035966 82 0.016
regulation of cellular metabolic process GO:0031323 305 0.016
Fly
gonad development GO:0008406 840 0.016
positive regulation of multicellular organism growth GO:0040018 352 0.015
catabolic process GO:0009056 318 0.015
protein modification by small protein conjugation GO:0032446 31 0.015
small molecule metabolic process GO:0044281 186 0.015
cellular catabolic process GO:0044248 199 0.015
phosphorylation GO:0016310 116 0.015
Human Zebrafish Mouse Fly
negative regulation of cell communication GO:0010648 61 0.015
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.015
organ morphogenesis GO:0009887 67 0.014
cell projection organization GO:0030030 231 0.014
organelle localization GO:0051640 127 0.014
epithelial cell proliferation GO:0050673 1 0.014
gene silencing by rna GO:0031047 143 0.014
amine metabolic process GO:0009308 15 0.014
mating GO:0007618 34 0.014
regulation of signaling GO:0023051 172 0.014
Fly
female gamete generation GO:0007292 254 0.014
response to unfolded protein GO:0006986 71 0.014
regulation of gene expression GO:0010468 366 0.014
Human Mouse
cellular amino acid metabolic process GO:0006520 15 0.014
positive regulation of metabolic process GO:0009893 187 0.014
ribonucleoprotein complex assembly GO:0022618 4 0.014
aromatic compound catabolic process GO:0019439 116 0.014
regulation of intracellular signal transduction GO:1902531 77 0.014
Fly
anatomical structure formation involved in morphogenesis GO:0048646 250 0.014
phosphorus metabolic process GO:0006793 232 0.014
Human Zebrafish Mouse Fly
neuron development GO:0048666 199 0.014
post embryonic organ development GO:0048569 336 0.014
gene silencing GO:0016458 143 0.013
positive regulation of cell cycle GO:0045787 55 0.013
organic cyclic compound biosynthetic process GO:1901362 195 0.013
single organism localization GO:1902578 518 0.013
regulation of cell morphogenesis GO:0022604 40 0.013
Fly
regulation of protein ubiquitination GO:0031396 3 0.013
negative regulation of cellular protein metabolic process GO:0032269 27 0.013
rna interference GO:0016246 137 0.013
protein modification by small protein conjugation or removal GO:0070647 40 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.013
sensory organ morphogenesis GO:0090596 2 0.013
cellular response to topologically incorrect protein GO:0035967 76 0.013
response to biotic stimulus GO:0009607 101 0.013
Mouse
nucleobase containing small molecule metabolic process GO:0055086 115 0.013
positive regulation of chromosome organization GO:2001252 2 0.012
regulation of metabolic process GO:0019222 478 0.012
Human Mouse Fly
regulation of meiotic cell cycle GO:0051445 136 0.012
regulation of lipid metabolic process GO:0019216 4 0.012
neuron projection development GO:0031175 187 0.012
neuron projection guidance GO:0097485 82 0.012
oogenesis GO:0048477 229 0.012
cellular localization GO:0051641 360 0.012
organic acid metabolic process GO:0006082 47 0.012
response to other organism GO:0051707 101 0.012
Mouse
signal transduction GO:0007165 317 0.012
Human Mouse Fly
aromatic compound biosynthetic process GO:0019438 192 0.012
cellular response to abiotic stimulus GO:0071214 4 0.012
regulation of apoptotic signaling pathway GO:2001233 1 0.012
microtubule based process GO:0007017 182 0.012
purine ribonucleotide metabolic process GO:0009150 95 0.012
nucleobase containing compound catabolic process GO:0034655 114 0.012
regulation of cell proliferation GO:0042127 105 0.011
phagocytosis GO:0006909 115 0.011
cell division GO:0051301 262 0.011
regulation of cell migration GO:0030334 55 0.011
enzyme linked receptor protein signaling pathway GO:0007167 50 0.011
Human
posttranscriptional gene silencing GO:0016441 143 0.011
regulation of primary metabolic process GO:0080090 292 0.011
long term memory GO:0007616 2 0.011
stress activated protein kinase signaling cascade GO:0031098 10 0.011
Fly
modification dependent protein catabolic process GO:0019941 32 0.011
negative regulation of macromolecule metabolic process GO:0010605 229 0.011
cellular macromolecule catabolic process GO:0044265 73 0.011
carboxylic acid metabolic process GO:0019752 34 0.011
germ cell development GO:0007281 351 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 32 0.011
regulation of mitotic cell cycle GO:0007346 76 0.011
intracellular receptor signaling pathway GO:0030522 2 0.011
positive regulation of biosynthetic process GO:0009891 109 0.011
axon guidance GO:0007411 82 0.010
rna localization GO:0006403 3 0.010
establishment or maintenance of cell polarity GO:0007163 63 0.010
macromolecular complex subunit organization GO:0043933 320 0.010
mitotic spindle organization GO:0007052 81 0.010
protein complex subunit organization GO:0071822 280 0.010

mak-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org