Caenorhabditis elegans

95 known processes

mec-3 (CELE_F01D4.6)

Protein MEC-3

mec-3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
development of primary sexual characteristics GO:0045137 840 0.413
Worm
transcription from rna polymerase ii promoter GO:0006366 149 0.324
cellular nitrogen compound biosynthetic process GO:0044271 192 0.258
single organism reproductive process GO:0044702 1196 0.249
Worm
rna biosynthetic process GO:0032774 169 0.220
post embryonic development GO:0009791 2152 0.217
Worm
sex differentiation GO:0007548 909 0.214
Worm
embryo development GO:0009790 3052 0.207
gene expression GO:0010467 412 0.202
regulation of nucleic acid templated transcription GO:1903506 165 0.183
regulation of macromolecule biosynthetic process GO:0010556 189 0.177
regulation of rna metabolic process GO:0051252 173 0.177
reproductive structure development GO:0048608 850 0.176
Worm
reproductive system development GO:0061458 850 0.172
Worm
positive regulation of nucleic acid templated transcription GO:1903508 102 0.166
localization of cell GO:0051674 313 0.152
Worm
organ development GO:0048513 1102 0.148
Worm
regulation of rna biosynthetic process GO:2001141 165 0.147
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.147
positive regulation of rna biosynthetic process GO:1902680 102 0.142
genitalia development GO:0048806 741 0.141
hermaphrodite genitalia development GO:0040035 734 0.139
embryo development ending in birth or egg hatching GO:0009792 2992 0.138
regulation of nitrogen compound metabolic process GO:0051171 222 0.137
cell migration GO:0016477 306 0.130
Worm
developmental process involved in reproduction GO:0003006 1165 0.128
Worm
vulval development GO:0040025 333 0.124
Worm
positive regulation of gene expression GO:0010628 112 0.123
biosynthetic process GO:0009058 323 0.122
transcription dna templated GO:0006351 168 0.121
muscle tissue development GO:0060537 1 0.121
neuron development GO:0048666 199 0.119
cellular component movement GO:0006928 388 0.118
Worm
regulation of metabolic process GO:0019222 478 0.117
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.117
regulation of macromolecule metabolic process GO:0060255 421 0.113
cellular component morphogenesis GO:0032989 318 0.113
Worm
negative regulation of macromolecule metabolic process GO:0010605 229 0.111
muscle structure development GO:0061061 191 0.111
nucleic acid metabolic process GO:0090304 299 0.106
nucleobase containing compound metabolic process GO:0006139 406 0.105
body morphogenesis GO:0010171 620 0.105
Worm
neurogenesis GO:0022008 236 0.103
positive regulation of metabolic process GO:0009893 187 0.103
positive regulation of transcription dna templated GO:0045893 102 0.103
head development GO:0060322 1 0.099
Worm
gamete generation GO:0007276 461 0.099
nucleic acid templated transcription GO:0097659 169 0.098
regulation of nematode larval development GO:0061062 260 0.097
Worm
endocytosis GO:0006897 819 0.097
locomotion GO:0040011 1634 0.094
Worm
gonad development GO:0008406 840 0.093
Worm
regulation of biological quality GO:0065008 741 0.092
regulation of gene expression GO:0010468 366 0.092
regulation of primary metabolic process GO:0080090 292 0.089
cell development GO:0048468 696 0.089
organic cyclic compound biosynthetic process GO:1901362 195 0.089
aging GO:0007568 812 0.088
rna metabolic process GO:0016070 228 0.087
negative regulation of metabolic process GO:0009892 240 0.087
multi organism reproductive process GO:0044703 867 0.086
Worm
positive regulation of biosynthetic process GO:0009891 109 0.086
positive regulation of rna metabolic process GO:0051254 103 0.086
negative regulation of nucleic acid templated transcription GO:1903507 53 0.085
vesicle mediated transport GO:0016192 852 0.084
cell death GO:0008219 547 0.084
positive regulation of macromolecule metabolic process GO:0010604 149 0.083
negative regulation of gene expression GO:0010629 217 0.081
negative regulation of biological process GO:0048519 567 0.081
Worm
regulation of transcription dna templated GO:0006355 164 0.080
cell projection morphogenesis GO:0048858 148 0.078
Worm
heterocycle biosynthetic process GO:0018130 187 0.078
pattern specification process GO:0007389 59 0.076
generation of neurons GO:0048699 235 0.074
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.072
behavior GO:0007610 527 0.072
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.071
protein catabolic process GO:0030163 162 0.070
negative regulation of transcription dna templated GO:0045892 53 0.070
determination of adult lifespan GO:0008340 812 0.069
transport GO:0006810 1093 0.068
muscle cell differentiation GO:0042692 171 0.067
positive regulation of cellular biosynthetic process GO:0031328 109 0.067
epithelial tube morphogenesis GO:0060562 1 0.067
cell motility GO:0048870 313 0.066
Worm
anatomical structure formation involved in morphogenesis GO:0048646 250 0.066
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.065
multicellular organismal aging GO:0010259 812 0.064
skeletal muscle organ development GO:0060538 3 0.064
post embryonic organ development GO:0048569 336 0.064
Worm
regulation of cell motility GO:2000145 57 0.064
Worm
cellular biosynthetic process GO:0044249 315 0.064
multi organism behavior GO:0051705 389 0.064
Worm
nucleobase containing compound biosynthetic process GO:0034654 184 0.063
cellular macromolecule biosynthetic process GO:0034645 247 0.063
cell projection organization GO:0030030 231 0.062
sexual reproduction GO:0019953 546 0.062
lipid localization GO:0010876 573 0.061
regulation of developmental process GO:0050793 684 0.060
Worm
maintenance of location GO:0051235 580 0.060
receptor mediated endocytosis GO:0006898 715 0.060
regulation of cellular biosynthetic process GO:0031326 189 0.059
cell fate commitment GO:0045165 139 0.059
Worm
apoptotic process GO:0006915 478 0.058
lipid storage GO:0019915 565 0.058
macromolecule localization GO:0033036 771 0.057
programmed cell death GO:0012501 500 0.057
multicellular organismal reproductive process GO:0048609 815 0.056
Worm
establishment of localization GO:0051234 1171 0.055
regulation of multicellular organismal development GO:2000026 317 0.055
Worm
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.054
positive regulation of cellular process GO:0048522 332 0.054
germ cell development GO:0007281 351 0.053
multicellular organism growth GO:0035264 385 0.052
regulation of cellular metabolic process GO:0031323 305 0.050
organic substance catabolic process GO:1901575 294 0.050
organic substance biosynthetic process GO:1901576 323 0.048
protein metabolic process GO:0019538 422 0.048
regulation of multicellular organism growth GO:0040014 373 0.048
developmental growth GO:0048589 412 0.047
nervous system development GO:0007399 253 0.047
single organism transport GO:0044765 447 0.047
regulation of developmental growth GO:0048638 389 0.047
death GO:0016265 547 0.047
positive regulation of developmental process GO:0051094 408 0.047
Worm
sensory organ morphogenesis GO:0090596 2 0.046
neuron differentiation GO:0030182 217 0.046
positive regulation of nematode larval development GO:0061063 54 0.046
Worm
macromolecule catabolic process GO:0009057 202 0.046
regulation of biosynthetic process GO:0009889 189 0.045
striated muscle cell differentiation GO:0051146 158 0.044
neuron projection morphogenesis GO:0048812 114 0.044
Worm
single organism signaling GO:0044700 401 0.044
Worm
signal transduction GO:0007165 317 0.043
Worm
regulation of multicellular organismal process GO:0051239 726 0.043
Worm
multicellular organism reproduction GO:0032504 819 0.043
Worm
growth GO:0040007 562 0.043
positive regulation of vulval development GO:0040026 52 0.042
Worm
tissue development GO:0009888 112 0.042
aromatic compound biosynthetic process GO:0019438 192 0.041
single organism localization GO:1902578 518 0.040
cellular component assembly GO:0022607 293 0.040
cell cycle process GO:0022402 482 0.040
reproductive behavior GO:0019098 387 0.039
Worm
positive regulation of developmental growth GO:0048639 354 0.038
muscle organ morphogenesis GO:0048644 4 0.038
multi organism reproductive behavior GO:0044705 387 0.038
Worm
cell cycle GO:0007049 526 0.037
positive regulation of growth GO:0045927 369 0.037
organelle organization GO:0006996 783 0.036
striated muscle cell development GO:0055002 157 0.036
cellular component biogenesis GO:0044085 297 0.036
oviposition GO:0018991 364 0.035
Worm
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.035
signaling GO:0023052 401 0.035
Worm
positive regulation of multicellular organism growth GO:0040018 352 0.035
catabolic process GO:0009056 318 0.035
negative regulation of cellular process GO:0048523 239 0.035
Worm
multicellular organismal reproductive behavior GO:0033057 384 0.034
Worm
molting cycle GO:0042303 281 0.034
multi multicellular organism process GO:0044706 390 0.034
Worm
regulation of localization GO:0032879 194 0.034
Worm
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.034
neuron projection development GO:0031175 187 0.033
regulation of post embryonic development GO:0048580 260 0.033
Worm
actin cytoskeleton organization GO:0030036 184 0.033
axon development GO:0061564 163 0.032
Worm
tissue morphogenesis GO:0048729 65 0.032
dauer larval development GO:0040024 92 0.032
Worm
negative regulation of biosynthetic process GO:0009890 65 0.032
female gamete generation GO:0007292 254 0.031
cellular localization GO:0051641 360 0.031
negative regulation of cellular biosynthetic process GO:0031327 65 0.030
defense response GO:0006952 296 0.030
positive regulation of neurogenesis GO:0050769 4 0.029
digestive system development GO:0055123 122 0.029
Worm
establishment of localization in cell GO:0051649 318 0.028
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.028
regulation of locomotion GO:0040012 161 0.028
Worm
macromolecule biosynthetic process GO:0009059 250 0.028
regulation of vulval development GO:0040028 248 0.027
Worm
cellular component assembly involved in morphogenesis GO:0010927 183 0.027
cell morphogenesis involved in differentiation GO:0000904 112 0.027
Worm
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.027
regulation of growth GO:0040008 409 0.027
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.027
neuron recognition GO:0008038 83 0.026
Worm
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.026
small molecule metabolic process GO:0044281 186 0.026
Worm
positive regulation of cellular metabolic process GO:0031325 178 0.026
positive regulation of multicellular organismal process GO:0051240 417 0.026
Worm
positive regulation of post embryonic development GO:0048582 54 0.026
Worm
cell morphogenesis GO:0000902 163 0.026
Worm
tube development GO:0035295 126 0.025
Worm
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.025
regulation of cell differentiation GO:0045595 81 0.025
Worm
negative regulation of rna metabolic process GO:0051253 53 0.025
actin filament based process GO:0030029 191 0.024
negative regulation of rna biosynthetic process GO:1902679 53 0.024
cytoskeleton organization GO:0007010 339 0.024
apoptotic cell clearance GO:0043277 111 0.024
cell division GO:0051301 262 0.024
cell proliferation GO:0008283 116 0.023
eating behavior GO:0042755 59 0.023
response to wounding GO:0009611 4 0.023
regulation of cellular component organization GO:0051128 248 0.023
protein complex subunit organization GO:0071822 280 0.023
macromolecule modification GO:0043412 218 0.022
neuron projection guidance GO:0097485 82 0.022
macromolecular complex subunit organization GO:0043933 320 0.022
response to abiotic stimulus GO:0009628 152 0.022
response to chemical GO:0042221 356 0.022
Worm
single organism organelle organization GO:1902589 501 0.022
meiotic cell cycle GO:0051321 335 0.021
negative regulation of developmental process GO:0051093 227 0.021
digestive tract development GO:0048565 122 0.021
Worm
epithelium development GO:0060429 68 0.021
cellular response to chemical stimulus GO:0070887 129 0.021
response to bacterium GO:0009617 86 0.021
regulation of epithelial cell proliferation GO:0050678 1 0.021
dendrite development GO:0016358 42 0.021
regulation of cell migration GO:0030334 55 0.021
Worm
adult behavior GO:0030534 3 0.020
cellular protein metabolic process GO:0044267 279 0.020
embryonic morphogenesis GO:0048598 152 0.020
regulation of gene expression epigenetic GO:0040029 163 0.020
intracellular receptor signaling pathway GO:0030522 2 0.020
cellular macromolecular complex assembly GO:0034622 184 0.020
regulation of cell cycle GO:0051726 194 0.020
regulation of lipid metabolic process GO:0019216 4 0.020
oogenesis GO:0048477 229 0.019
system process GO:0003008 136 0.019
Worm
positive regulation of intracellular transport GO:0032388 2 0.019
rho protein signal transduction GO:0007266 2 0.019
organonitrogen compound metabolic process GO:1901564 151 0.019
Worm
posttranscriptional gene silencing by rna GO:0035194 143 0.019
gene silencing GO:0016458 143 0.019
muscle cell development GO:0055001 158 0.019
negative regulation of post embryonic development GO:0048581 208 0.019
negative regulation of vulval development GO:0040027 206 0.019
embryonic pattern specification GO:0009880 21 0.018
muscle fiber development GO:0048747 2 0.018
organic acid metabolic process GO:0006082 47 0.018
Worm
cell type specific apoptotic process GO:0097285 4 0.018
myosin filament assembly GO:0031034 138 0.018
myofibril assembly GO:0030239 154 0.018
organelle assembly GO:0070925 214 0.018
cell fate specification involved in pattern specification GO:0060573 4 0.018
monocarboxylic acid biosynthetic process GO:0072330 13 0.017
Worm
axonal fasciculation GO:0007413 79 0.017
Worm
organelle fission GO:0048285 363 0.017
chemosensory behavior GO:0007635 33 0.017
Worm
regulation of cell communication GO:0010646 176 0.017
Worm
cellular protein complex assembly GO:0043623 178 0.017
response to other organism GO:0051707 101 0.017
chemotaxis GO:0006935 120 0.017
negative regulation of cellular metabolic process GO:0031324 95 0.017
organ morphogenesis GO:0009887 67 0.017
Worm
phagocytosis GO:0006909 115 0.017
myosin filament organization GO:0031033 138 0.017
protein localization GO:0008104 205 0.017
posttranscriptional gene silencing GO:0016441 143 0.016
protein modification process GO:0036211 207 0.016
response to external stimulus GO:0009605 289 0.016
gene silencing by rna GO:0031047 143 0.016
regulation of apoptotic signaling pathway GO:2001233 1 0.016
regulation of cell proliferation GO:0042127 105 0.016
negative regulation of neurogenesis GO:0050768 4 0.016
meiotic nuclear division GO:0007126 300 0.016
axon guidance GO:0007411 82 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.016
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.016
Worm
positive regulation of neuron differentiation GO:0045666 4 0.016
rna interference GO:0016246 137 0.016
negative regulation of nematode larval development GO:0061064 208 0.016
regulation of cytoplasmic transport GO:1903649 3 0.016
taxis GO:0042330 128 0.016
Worm
feeding behavior GO:0007631 70 0.016
lipid metabolic process GO:0006629 77 0.016
establishment of organelle localization GO:0051656 123 0.016
epithelial cell proliferation GO:0050673 1 0.015
regulation of protein localization GO:0032880 50 0.015
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.015
single organism behavior GO:0044708 83 0.015
posttranscriptional regulation of gene expression GO:0010608 166 0.015
oxoacid metabolic process GO:0043436 47 0.015
Worm
pharyngeal pumping GO:0043050 58 0.015
protein complex assembly GO:0006461 186 0.015
protein complex biogenesis GO:0070271 186 0.014
regulation of cell cycle process GO:0010564 145 0.014
signal release GO:0023061 28 0.014
negative regulation of multicellular organismal process GO:0051241 236 0.014
response to organic substance GO:0010033 131 0.014
positive regulation of protein transport GO:0051222 4 0.014
secretion GO:0046903 147 0.014
pigmentation GO:0043473 2 0.014
cuticle development GO:0042335 100 0.014
response to biotic stimulus GO:0009607 101 0.014
cellular protein modification process GO:0006464 207 0.014
regulation of neurogenesis GO:0050767 40 0.014
Worm
detection of external stimulus GO:0009581 4 0.013
Worm
response to external biotic stimulus GO:0043207 101 0.013
cellular amino acid metabolic process GO:0006520 15 0.013
Worm
regulation of cellular amine metabolic process GO:0033238 0 0.013
male sex differentiation GO:0046661 86 0.013
negative regulation of response to external stimulus GO:0032102 3 0.013
small gtpase mediated signal transduction GO:0007264 32 0.013
regulation of response to wounding GO:1903034 1 0.013
regulation of gastrulation GO:0010470 4 0.013
striated muscle myosin thick filament assembly GO:0071688 138 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
phagocytosis engulfment GO:0006911 98 0.012
male anatomical structure morphogenesis GO:0090598 78 0.012
negative regulation of response to stimulus GO:0048585 73 0.012
Worm
regulation of mitotic cell cycle GO:0007346 76 0.012
positive regulation of epithelial cell proliferation GO:0050679 1 0.012
cellular amine metabolic process GO:0044106 15 0.012
collagen and cuticulin based cuticle development GO:0040002 99 0.012
secretion by cell GO:0032940 138 0.012
excretion GO:0007588 49 0.012
Worm
regulation of nervous system development GO:0051960 41 0.012
Worm
positive regulation of cell projection organization GO:0031346 4 0.012
cell surface receptor signaling pathway GO:0007166 149 0.012
neuromuscular junction development GO:0007528 2 0.012
developmental cell growth GO:0048588 39 0.012
regulation of lipid biosynthetic process GO:0046890 1 0.012
asymmetric cell division GO:0008356 36 0.012
regulation of protein targeting GO:1903533 3 0.012
intracellular transport GO:0046907 77 0.012
regulation of cell division GO:0051302 142 0.012
axon extension GO:0048675 37 0.012
regulation of protein import into nucleus GO:0042306 3 0.012
regulation of cellular protein metabolic process GO:0032268 75 0.012
regulation of stem cell differentiation GO:2000736 1 0.012
amine metabolic process GO:0009308 15 0.012
negative regulation of neuron differentiation GO:0045665 4 0.012
actomyosin structure organization GO:0031032 154 0.011
homeostatic process GO:0042592 51 0.011
regulation of cellular component size GO:0032535 40 0.011
regulation of meiotic cell cycle GO:0051445 136 0.011
single organism intracellular transport GO:1902582 70 0.011
neuron projection extension GO:1990138 37 0.011
cell recognition GO:0008037 85 0.011
Worm
nematode male tail tip morphogenesis GO:0045138 77 0.011
membrane invagination GO:0010324 98 0.011
regulation of epithelial cell differentiation GO:0030856 4 0.011
positive regulation of jnk cascade GO:0046330 3 0.011
regeneration GO:0031099 4 0.011
regulation of signal transduction GO:0009966 135 0.011
Worm
intracellular signal transduction GO:0035556 96 0.011
canonical wnt signaling pathway GO:0060070 3 0.011
mechanosensory behavior GO:0007638 25 0.011
engulfment of apoptotic cell GO:0043652 94 0.011
regulation of nucleocytoplasmic transport GO:0046822 3 0.011
macromolecular complex assembly GO:0065003 193 0.011
regulation of organ morphogenesis GO:2000027 4 0.011
nonmotile primary cilium assembly GO:0035058 18 0.011
developmental growth involved in morphogenesis GO:0060560 37 0.011
response to temperature stimulus GO:0009266 66 0.011
Worm
positive regulation of organ growth GO:0046622 4 0.011
regulation of cell death GO:0010941 65 0.011
phosphate containing compound metabolic process GO:0006796 232 0.011
carboxylic acid metabolic process GO:0019752 34 0.010
Worm
ras protein signal transduction GO:0007265 31 0.010
negative regulation of cell communication GO:0010648 61 0.010
Worm
cellular response to stress GO:0033554 162 0.010
g1 s transition of mitotic cell cycle GO:0000082 2 0.010
mesoderm development GO:0007498 27 0.010
membrane organization GO:0061024 135 0.010
regulation of cellular component movement GO:0051270 62 0.010
Worm
gastrulation GO:0007369 58 0.010
cilium organization GO:0044782 32 0.010
adult locomotory behavior GO:0008344 1 0.010
positive regulation of intracellular protein transport GO:0090316 2 0.010

mec-3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
organ system cancer DOID:0050686 0 0.012
nervous system disease DOID:863 0 0.012