Caenorhabditis elegans

39 known processes

gpd-4 (CELE_F33H1.2)

Protein GPD-4

gpd-4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
female gamete generation GO:0007292 254 0.913
single organism reproductive process GO:0044702 1196 0.803
embryo development ending in birth or egg hatching GO:0009792 2992 0.776
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.766
sexual reproduction GO:0019953 546 0.746
germ cell development GO:0007281 351 0.727
multicellular organism reproduction GO:0032504 819 0.726
single fertilization GO:0007338 61 0.713
oogenesis GO:0048477 229 0.666
embryo development GO:0009790 3052 0.631
cell cycle process GO:0022402 482 0.580
single organism organelle organization GO:1902589 501 0.578
meiotic cell cycle process GO:1903046 170 0.573
multicellular organismal reproductive process GO:0048609 815 0.557
multi organism reproductive process GO:0044703 867 0.544
gamete generation GO:0007276 461 0.516
oocyte differentiation GO:0009994 45 0.464
negative regulation of biological process GO:0048519 567 0.437
Human Mouse
microtubule based process GO:0007017 182 0.424
pronuclear migration GO:0035046 51 0.405
meiotic cell cycle GO:0051321 335 0.404
organelle organization GO:0006996 783 0.360
post embryonic development GO:0009791 2152 0.345
spindle organization GO:0007051 92 0.326
organic substance biosynthetic process GO:1901576 323 0.323
Human Mouse
organelle fission GO:0048285 363 0.297
fertilization GO:0009566 63 0.294
mitotic spindle organization GO:0007052 81 0.289
taxis GO:0042330 128 0.278
oocyte development GO:0048599 44 0.274
mitotic nuclear division GO:0007067 89 0.271
receptor mediated endocytosis GO:0006898 715 0.256
mitotic cell cycle process GO:1903047 194 0.248
cell division GO:0051301 262 0.245
cell cycle GO:0007049 526 0.242
meiotic nuclear division GO:0007126 300 0.242
programmed cell death GO:0012501 500 0.241
establishment of localization GO:0051234 1171 0.235
meiotic chromosome segregation GO:0045132 139 0.234
phosphorus metabolic process GO:0006793 232 0.217
cell development GO:0048468 696 0.211
macromolecular complex subunit organization GO:0043933 320 0.206
chemotaxis GO:0006935 120 0.198
spermatogenesis GO:0007283 41 0.194
death GO:0016265 547 0.183
developmental process involved in reproduction GO:0003006 1165 0.182
response to chemical GO:0042221 356 0.175
Human
establishment of localization in cell GO:0051649 318 0.175
cell death GO:0008219 547 0.171
regulation of gene expression GO:0010468 366 0.169
Human Mouse
cellular localization GO:0051641 360 0.162
multi organism reproductive behavior GO:0044705 387 0.156
transport GO:0006810 1093 0.152
protein catabolic process GO:0030163 162 0.148
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.148
Human Mouse
regulation of multicellular organismal process GO:0051239 726 0.145
locomotion GO:0040011 1634 0.141
Mouse
single organism localization GO:1902578 518 0.140
cytoskeleton organization GO:0007010 339 0.137
aromatic compound biosynthetic process GO:0019438 192 0.134
determination of adult lifespan GO:0008340 812 0.133
Worm
protein metabolic process GO:0019538 422 0.132
Human Mouse
protein complex subunit organization GO:0071822 280 0.132
dna metabolic process GO:0006259 74 0.131
nucleus localization GO:0051647 55 0.130
nucleotide metabolic process GO:0009117 108 0.127
negative regulation of cellular metabolic process GO:0031324 95 0.126
Human Mouse
regulation of metabolic process GO:0019222 478 0.126
Human Mouse
nuclear migration GO:0007097 54 0.121
organic substance catabolic process GO:1901575 294 0.120
Mouse Fly
regulation of biological quality GO:0065008 741 0.119
Worm
organophosphate metabolic process GO:0019637 125 0.118
apoptotic process GO:0006915 478 0.117
cytokinesis GO:0000910 80 0.116
single organism signaling GO:0044700 401 0.112
endocytosis GO:0006897 819 0.109
establishment of mitotic spindle localization GO:0040001 41 0.108
cellular component biogenesis GO:0044085 297 0.108
cellular macromolecular complex assembly GO:0034622 184 0.108
multicellular organismal aging GO:0010259 812 0.107
Worm
organic cyclic compound catabolic process GO:1901361 119 0.105
organ development GO:0048513 1102 0.104
organelle assembly GO:0070925 214 0.104
negative regulation of gene expression GO:0010629 217 0.104
Human Mouse
aging GO:0007568 812 0.102
Worm
organelle localization GO:0051640 127 0.099
phosphate containing compound metabolic process GO:0006796 232 0.096
cellular response to stress GO:0033554 162 0.096
purine nucleoside catabolic process GO:0006152 75 0.095
genitalia development GO:0048806 741 0.094
cellular biosynthetic process GO:0044249 315 0.091
Human Mouse
negative regulation of vulval development GO:0040027 206 0.089
neuron projection guidance GO:0097485 82 0.087
ribonucleoside triphosphate catabolic process GO:0009203 72 0.087
hermaphrodite genitalia development GO:0040035 734 0.087
microtubule polymerization or depolymerization GO:0031109 22 0.086
negative regulation of cellular process GO:0048523 239 0.086
Human Mouse
negative regulation of nematode larval development GO:0061064 208 0.085
positive regulation of cellular process GO:0048522 332 0.084
regulation of cellular metabolic process GO:0031323 305 0.084
Human Mouse
regulation of macromolecule metabolic process GO:0060255 421 0.084
Human Mouse
cell part morphogenesis GO:0032990 152 0.084
ribonucleoside triphosphate metabolic process GO:0009199 87 0.083
multicellular organismal reproductive behavior GO:0033057 384 0.082
purine ribonucleoside monophosphate metabolic process GO:0009167 43 0.082
biosynthetic process GO:0009058 323 0.081
Human Mouse
chromosome organization GO:0051276 104 0.081
male gamete generation GO:0048232 41 0.080
multi organism behavior GO:0051705 389 0.077
gonad development GO:0008406 840 0.077
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.077
purine containing compound catabolic process GO:0072523 75 0.077
regulation of developmental process GO:0050793 684 0.076
behavior GO:0007610 527 0.076
vesicle mediated transport GO:0016192 852 0.076
establishment of spindle localization GO:0051293 51 0.075
cellular macromolecule biosynthetic process GO:0034645 247 0.074
Human Mouse
spindle localization GO:0051653 51 0.074
macromolecule catabolic process GO:0009057 202 0.074
oocyte axis specification GO:0007309 2 0.074
chromosome segregation GO:0007059 180 0.073
specification of axis polarity GO:0065001 13 0.073
attachment of spindle microtubules to kinetochore GO:0008608 8 0.072
nucleobase containing small molecule metabolic process GO:0055086 115 0.071
macromolecule localization GO:0033036 771 0.070
Worm
purine nucleotide metabolic process GO:0006163 95 0.070
pattern specification process GO:0007389 59 0.070
response to external stimulus GO:0009605 289 0.069
single organism transport GO:0044765 447 0.067
negative regulation of post embryonic development GO:0048581 208 0.066
regulation of cell cycle GO:0051726 194 0.066
reproductive behavior GO:0019098 387 0.064
anatomical structure formation involved in morphogenesis GO:0048646 250 0.064
Fly
development of primary sexual characteristics GO:0045137 840 0.064
nucleoside metabolic process GO:0009116 99 0.062
ribonucleotide metabolic process GO:0009259 99 0.061
maintenance of protein location in cell GO:0032507 12 0.059
glycosyl compound metabolic process GO:1901657 100 0.059
cellular component assembly GO:0022607 293 0.059
multi multicellular organism process GO:0044706 390 0.058
aromatic compound catabolic process GO:0019439 116 0.058
generation of neurons GO:0048699 235 0.057
maintenance of location GO:0051235 580 0.057
Worm
positive regulation of cellular metabolic process GO:0031325 178 0.057
regulation of cellular biosynthetic process GO:0031326 189 0.057
Human Mouse
spindle assembly involved in mitosis GO:0090307 6 0.057
negative regulation of cellular biosynthetic process GO:0031327 65 0.056
Human Mouse
regulation of meiotic cell cycle GO:0051445 136 0.056
positive regulation of metabolic process GO:0009893 187 0.056
organonitrogen compound metabolic process GO:1901564 151 0.055
lipid localization GO:0010876 573 0.055
Worm
posttranscriptional regulation of gene expression GO:0010608 166 0.055
Human Mouse
regulation of mitotic spindle organization GO:0060236 3 0.055
nucleic acid metabolic process GO:0090304 299 0.055
negative regulation of developmental process GO:0051093 227 0.054
purine ribonucleoside metabolic process GO:0046128 92 0.053
negative regulation of metabolic process GO:0009892 240 0.052
Human Mouse
small molecule metabolic process GO:0044281 186 0.052
Mouse Fly
protein phosphorylation GO:0006468 85 0.052
cellular component morphogenesis GO:0032989 318 0.052
oocyte construction GO:0007308 2 0.052
neuron differentiation GO:0030182 217 0.052
cell projection morphogenesis GO:0048858 148 0.051
lipid storage GO:0019915 565 0.051
Worm
pole plasm assembly GO:0007315 2 0.051
oviposition GO:0018991 364 0.050
regulation of response to stimulus GO:0048583 243 0.050
regulation of cellular protein metabolic process GO:0032268 75 0.050
Human Mouse
cell cycle phase transition GO:0044770 19 0.050
regulation of multicellular organismal development GO:2000026 317 0.049
negative regulation of multicellular organismal process GO:0051241 236 0.049
regulation of rna biosynthetic process GO:2001141 165 0.048
regulation of biosynthetic process GO:0009889 189 0.048
Human Mouse
nucleoside catabolic process GO:0009164 78 0.048
cellular nitrogen compound catabolic process GO:0044270 119 0.048
purine nucleotide catabolic process GO:0006195 75 0.047
macromolecular complex assembly GO:0065003 193 0.047
regulation of primary metabolic process GO:0080090 292 0.047
Human Mouse
actin cytoskeleton organization GO:0030036 184 0.047
negative regulation of macromolecule metabolic process GO:0010605 229 0.047
Human Mouse
protein complex biogenesis GO:0070271 186 0.046
negative regulation of nucleic acid templated transcription GO:1903507 53 0.046
cell projection organization GO:0030030 231 0.045
regulation of cell division GO:0051302 142 0.045
regulation of phosphorus metabolic process GO:0051174 81 0.045
cell volume homeostasis GO:0006884 1 0.044
microtubule cytoskeleton organization involved in mitosis GO:1902850 12 0.044
single organism catabolic process GO:0044712 129 0.044
Mouse Fly
nucleobase containing compound metabolic process GO:0006139 406 0.044
positive regulation of macromolecule metabolic process GO:0010604 149 0.044
nucleotide catabolic process GO:0009166 77 0.043
axon development GO:0061564 163 0.043
nucleobase containing compound catabolic process GO:0034655 114 0.043
cellular protein modification process GO:0006464 207 0.043
protein complex assembly GO:0006461 186 0.042
macromolecule modification GO:0043412 218 0.042
cellular nitrogen compound biosynthetic process GO:0044271 192 0.042
establishment of organelle localization GO:0051656 123 0.041
organophosphate catabolic process GO:0046434 81 0.041
carbohydrate derivative catabolic process GO:1901136 82 0.041
organic cyclic compound biosynthetic process GO:1901362 195 0.041
organonitrogen compound catabolic process GO:1901565 90 0.041
cellular protein metabolic process GO:0044267 279 0.040
Human Mouse
negative regulation of transcription dna templated GO:0045892 53 0.039
cytoskeleton dependent cytokinesis GO:0061640 35 0.039
macromolecule biosynthetic process GO:0009059 250 0.038
Human Mouse
cellular catabolic process GO:0044248 199 0.038
purine nucleoside metabolic process GO:0042278 92 0.038
regulation of gene expression epigenetic GO:0040029 163 0.038
embryonic pattern specification GO:0009880 21 0.038
body morphogenesis GO:0010171 620 0.037
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.037
Human Mouse
neuron development GO:0048666 199 0.036
neuron projection development GO:0031175 187 0.036
cellular protein complex assembly GO:0043623 178 0.036
nucleoside phosphate metabolic process GO:0006753 108 0.036
response to abiotic stimulus GO:0009628 152 0.035
cell morphogenesis GO:0000902 163 0.035
ribonucleoside catabolic process GO:0042454 77 0.035
positive regulation of multicellular organismal process GO:0051240 417 0.034
vulval development GO:0040025 333 0.034
sensory organ morphogenesis GO:0090596 2 0.033
atp metabolic process GO:0046034 42 0.033
multicellular organism growth GO:0035264 385 0.033
post embryonic organ development GO:0048569 336 0.033
microtubule anchoring GO:0034453 8 0.033
regulation of nematode larval development GO:0061062 260 0.033
nucleic acid templated transcription GO:0097659 169 0.032
cellular response to dna damage stimulus GO:0006974 41 0.032
regulation of developmental growth GO:0048638 389 0.032
positive regulation of multicellular organism growth GO:0040018 352 0.032
gene silencing GO:0016458 143 0.032
axon guidance GO:0007411 82 0.031
regulation of growth GO:0040008 409 0.031
transcription dna templated GO:0006351 168 0.031
regulation of macromolecule biosynthetic process GO:0010556 189 0.031
Human Mouse
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.030
Human Mouse
regulation of mitotic cell cycle GO:0007346 76 0.030
gene expression GO:0010467 412 0.030
Human Mouse
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.030
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.030
nervous system development GO:0007399 253 0.029
muscle cell differentiation GO:0042692 171 0.029
Fly
neurogenesis GO:0022008 236 0.029
system process GO:0003008 136 0.029
reproductive system development GO:0061458 850 0.029
establishment of nucleus localization GO:0040023 55 0.028
cellular component movement GO:0006928 388 0.028
Mouse
ribonucleoside metabolic process GO:0009119 98 0.028
developmental growth GO:0048589 412 0.028
dna duplex unwinding GO:0032508 3 0.028
membrane organization GO:0061024 135 0.028
heterocycle biosynthetic process GO:0018130 187 0.027
response to wounding GO:0009611 4 0.026
posttranscriptional gene silencing GO:0016441 143 0.026
purine containing compound metabolic process GO:0072521 95 0.026
establishment of cell polarity GO:0030010 46 0.026
regulation of signal transduction GO:0009966 135 0.026
regulation of nucleic acid templated transcription GO:1903506 165 0.026
regulation of vulval development GO:0040028 248 0.026
nucleoside phosphate catabolic process GO:1901292 77 0.026
cellular component assembly involved in morphogenesis GO:0010927 183 0.026
negative regulation of cell cycle GO:0045786 53 0.026
cell fate commitment GO:0045165 139 0.025
regulation of post embryonic development GO:0048580 260 0.025
regulation of microtubule cytoskeleton organization GO:0070507 21 0.025
meiosis i GO:0007127 19 0.025
mitotic spindle stabilization GO:0043148 2 0.025
positive regulation of developmental process GO:0051094 408 0.024
mitotic sister chromatid segregation GO:0000070 38 0.024
regionalization GO:0003002 31 0.024
negative regulation of biosynthetic process GO:0009890 65 0.024
Human Mouse
head development GO:0060322 1 0.024
positive regulation of developmental growth GO:0048639 354 0.024
regulation of cell cycle process GO:0010564 145 0.024
dna conformation change GO:0071103 11 0.024
regulation of behavior GO:0050795 97 0.024
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.023
rna metabolic process GO:0016070 228 0.023
ribonucleotide catabolic process GO:0009261 75 0.023
rna biosynthetic process GO:0032774 169 0.023
proteolysis involved in cellular protein catabolic process GO:0051603 32 0.023
carbohydrate derivative metabolic process GO:1901135 141 0.023
muscle tissue development GO:0060537 1 0.023
phosphorylation GO:0016310 116 0.022
localization of cell GO:0051674 313 0.022
Mouse
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.022
actin filament based process GO:0030029 191 0.022
posttranscriptional gene silencing by rna GO:0035194 143 0.022
purine ribonucleoside catabolic process GO:0046130 75 0.022
ion transport GO:0006811 113 0.022
glycosyl compound catabolic process GO:1901658 79 0.022
heterocycle catabolic process GO:0046700 119 0.022
signal transduction GO:0007165 317 0.021
ribose phosphate metabolic process GO:0019693 99 0.021
negative regulation of protein metabolic process GO:0051248 27 0.021
Human Mouse
purine ribonucleotide catabolic process GO:0009154 75 0.021
regulation of localization GO:0032879 194 0.021
cell morphogenesis involved in differentiation GO:0000904 112 0.021
nucleoside triphosphate metabolic process GO:0009141 87 0.020
regulation of phosphorylation GO:0042325 45 0.020
purine ribonucleotide metabolic process GO:0009150 95 0.020
regulation of protein metabolic process GO:0051246 81 0.020
Human Mouse
regulation of multi organism process GO:0043900 69 0.020
purine nucleoside triphosphate catabolic process GO:0009146 72 0.020
cell migration GO:0016477 306 0.020
establishment or maintenance of cell polarity GO:0007163 63 0.020
purine nucleoside triphosphate metabolic process GO:0009144 87 0.020
embryonic morphogenesis GO:0048598 152 0.020
nucleoside monophosphate metabolic process GO:0009123 46 0.020
cell motility GO:0048870 313 0.020
Mouse
homeostatic process GO:0042592 51 0.020
neuron projection morphogenesis GO:0048812 114 0.019
regulation of organelle organization GO:0033043 164 0.019
developmental maturation GO:0021700 26 0.019
synaptonemal complex assembly GO:0007130 6 0.019
regulation of multicellular organism growth GO:0040014 373 0.019
regulation of catalytic activity GO:0050790 78 0.019
regulation of signaling GO:0023051 172 0.019
nucleoside triphosphate catabolic process GO:0009143 72 0.018
pharyngeal pumping GO:0043050 58 0.018
regulation of nuclear division GO:0051783 115 0.018
positive regulation of growth GO:0045927 369 0.018
ion transmembrane transport GO:0034220 91 0.018
chemosensory behavior GO:0007635 33 0.018
muscle structure development GO:0061061 191 0.018
Fly
cellular macromolecule localization GO:0070727 75 0.018
metaphase plate congression GO:0051310 5 0.017
negative regulation of rna biosynthetic process GO:1902679 53 0.017
feeding behavior GO:0007631 70 0.017
purine nucleoside monophosphate catabolic process GO:0009128 28 0.017
mitotic nuclear envelope reassembly GO:0007084 3 0.017
protein modification process GO:0036211 207 0.017
establishment of mitotic spindle orientation GO:0000132 28 0.017
cell maturation GO:0048469 26 0.017
gene silencing by rna GO:0031047 143 0.017
catabolic process GO:0009056 318 0.017
Mouse Fly
peptidyl serine phosphorylation GO:0018105 20 0.016
regulation of cellular component organization GO:0051128 248 0.016
maintenance of location in cell GO:0051651 12 0.016
regulation of protein kinase activity GO:0045859 28 0.016
kinetochore organization GO:0051383 7 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.016
myofibril assembly GO:0030239 154 0.016
muscle cell development GO:0055001 158 0.016
positive regulation of cell projection organization GO:0031346 4 0.016
striated muscle cell differentiation GO:0051146 158 0.015
Fly
membrane depolarization GO:0051899 1 0.015
positive regulation of cell cycle GO:0045787 55 0.015
cell cycle g2 m phase transition GO:0044839 1 0.015
actomyosin structure organization GO:0031032 154 0.015
sister chromatid segregation GO:0000819 46 0.015
anterior posterior pattern specification GO:0009952 27 0.015
axonogenesis GO:0007409 102 0.015
organic substance transport GO:0071702 113 0.014
axis specification GO:0009798 23 0.014
myosin filament assembly GO:0031034 138 0.014
modification dependent macromolecule catabolic process GO:0043632 32 0.014
atp catabolic process GO:0006200 27 0.014
anatomical structure homeostasis GO:0060249 11 0.014
positive regulation of cellular biosynthetic process GO:0031328 109 0.014
cell cycle switching mitotic to meiotic cell cycle GO:0051728 35 0.014
regulation of system process GO:0044057 27 0.014
dna recombination GO:0006310 19 0.014
cell recognition GO:0008037 85 0.014
intracellular transport GO:0046907 77 0.014
response to inorganic substance GO:0010035 50 0.014
regulation of meiosis GO:0040020 94 0.014
single organism cellular localization GO:1902580 72 0.014
striated muscle cell development GO:0055002 157 0.013
sex differentiation GO:0007548 909 0.013
rna interference GO:0016246 137 0.013
myosin filament organization GO:0031033 138 0.013
response to other organism GO:0051707 101 0.013
growth GO:0040007 562 0.013
tissue development GO:0009888 112 0.013
cell proliferation GO:0008283 116 0.013
positive regulation of biosynthetic process GO:0009891 109 0.013
single organism biosynthetic process GO:0044711 91 0.013
regulation of attachment of spindle microtubules to kinetochore GO:0051988 2 0.013
dna replication GO:0006260 15 0.013
cellular response to abiotic stimulus GO:0071214 4 0.013
phagocytosis engulfment GO:0006911 98 0.013
eating behavior GO:0042755 59 0.013
membrane invagination GO:0010324 98 0.013
regulation of apoptotic process GO:0042981 36 0.012
regulation of nitrogen compound metabolic process GO:0051171 222 0.012
spindle assembly GO:0051225 8 0.012
mitotic sister chromatid separation GO:0051306 13 0.012
signaling GO:0023052 401 0.012
regulation of catabolic process GO:0009894 57 0.012
negative regulation of rna metabolic process GO:0051253 53 0.012
negative regulation of cellular protein metabolic process GO:0032269 27 0.012
Human Mouse
intracellular signal transduction GO:0035556 96 0.012
epithelial cell proliferation GO:0050673 1 0.012
maintenance of protein location GO:0045185 15 0.012
regulation of cell cycle phase transition GO:1901987 13 0.012
purine nucleoside monophosphate metabolic process GO:0009126 43 0.012
secretion GO:0046903 147 0.012
regulation of cell proliferation GO:0042127 105 0.012
establishment of chromosome localization GO:0051303 10 0.012
regulation of mitosis GO:0007088 18 0.012
chromosome organization involved in meiosis GO:0070192 25 0.012
regulation of transcription dna templated GO:0006355 164 0.012
regulation of chromosome segregation GO:0051983 20 0.011
regulation of epithelial cell proliferation GO:0050678 1 0.011
hatching GO:0035188 48 0.011
positive regulation of chromosome organization GO:2001252 2 0.011
negative regulation of cell cycle g2 m phase transition GO:1902750 1 0.011
regulation of cell death GO:0010941 65 0.011
dna geometric change GO:0032392 3 0.011
cell cell signaling GO:0007267 118 0.011
mitotic g2 m transition checkpoint GO:0044818 1 0.011
regulation of reproductive process GO:2000241 66 0.011
protein localization GO:0008104 205 0.011
positive regulation of meiotic cell cycle GO:0051446 47 0.010
meiotic cytokinesis GO:0033206 15 0.010
ovulation GO:0030728 33 0.010
regulation of apoptotic signaling pathway GO:2001233 1 0.010
response to oxygen containing compound GO:1901700 44 0.010
reproductive structure development GO:0048608 850 0.010
cellular protein localization GO:0034613 75 0.010
apoptotic cell clearance GO:0043277 111 0.010
tube development GO:0035295 126 0.010
regulation of microtubule based process GO:0032886 21 0.010

gpd-4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.011