Caenorhabditis elegans

62 known processes

skp-1 (CELE_T27F2.1)

Protein SKP-1

skp-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism reproductive process GO:0044702 1196 0.932
embryo development ending in birth or egg hatching GO:0009792 2992 0.898
meiotic nuclear division GO:0007126 300 0.893
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.886
Human
cell cycle process GO:0022402 482 0.877
gene expression GO:0010467 412 0.875
sexual reproduction GO:0019953 546 0.862
regulation of rna biosynthetic process GO:2001141 165 0.848
Human
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.840
Human
embryo development GO:0009790 3052 0.829
cell cycle GO:0007049 526 0.823
organ development GO:0048513 1102 0.787
regulation of rna metabolic process GO:0051252 173 0.783
Human
development of primary sexual characteristics GO:0045137 840 0.775
meiotic cell cycle GO:0051321 335 0.761
nucleobase containing compound metabolic process GO:0006139 406 0.733
Human
sex differentiation GO:0007548 909 0.691
nucleic acid metabolic process GO:0090304 299 0.690
Human
regulation of nitrogen compound metabolic process GO:0051171 222 0.688
Human
developmental process involved in reproduction GO:0003006 1165 0.658
mitotic cell cycle process GO:1903047 194 0.651
regulation of macromolecule metabolic process GO:0060255 421 0.641
multicellular organism reproduction GO:0032504 819 0.641
meiotic cell cycle process GO:1903046 170 0.639
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.638
Human
rna metabolic process GO:0016070 228 0.624
Human
organic cyclic compound biosynthetic process GO:1901362 195 0.616
Human
locomotion GO:0040011 1634 0.607
receptor mediated endocytosis GO:0006898 715 0.601
positive regulation of macromolecule metabolic process GO:0010604 149 0.600
Human
hermaphrodite genitalia development GO:0040035 734 0.598
regulation of gene expression GO:0010468 366 0.592
heterocycle biosynthetic process GO:0018130 187 0.589
Human
regulation of metabolic process GO:0019222 478 0.588
transcription dna templated GO:0006351 168 0.588
Human
positive regulation of cellular biosynthetic process GO:0031328 109 0.573
Human
positive regulation of rna biosynthetic process GO:1902680 102 0.563
Human
reproductive system development GO:0061458 850 0.558
nucleic acid templated transcription GO:0097659 169 0.558
Human
regulation of nucleic acid templated transcription GO:1903506 165 0.552
Human
neurogenesis GO:0022008 236 0.542
biosynthetic process GO:0009058 323 0.539
Human
regulation of cell cycle GO:0051726 194 0.509
regulation of mitotic cell cycle GO:0007346 76 0.508
regulation of primary metabolic process GO:0080090 292 0.505
Human
transcription from rna polymerase ii promoter GO:0006366 149 0.500
Human
negative regulation of vulval development GO:0040027 206 0.499
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.497
gonad development GO:0008406 840 0.496
multicellular organismal reproductive process GO:0048609 815 0.449
vulval development GO:0040025 333 0.447
regulation of multicellular organismal process GO:0051239 726 0.445
rna biosynthetic process GO:0032774 169 0.439
Human
regulation of cellular biosynthetic process GO:0031326 189 0.428
Human
neuron projection development GO:0031175 187 0.420
transport GO:0006810 1093 0.403
genitalia development GO:0048806 741 0.396
gamete generation GO:0007276 461 0.391
macromolecule biosynthetic process GO:0009059 250 0.379
Human
regulation of vulval development GO:0040028 248 0.368
cellular biosynthetic process GO:0044249 315 0.367
Human
positive regulation of gene expression GO:0010628 112 0.359
Human
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.344
Human
establishment of localization GO:0051234 1171 0.343
regulation of macromolecule biosynthetic process GO:0010556 189 0.338
Human
regulation of cellular metabolic process GO:0031323 305 0.332
Human
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.318
Human
reproductive structure development GO:0048608 850 0.315
organelle fission GO:0048285 363 0.314
positive regulation of multicellular organismal process GO:0051240 417 0.302
meiotic chromosome segregation GO:0045132 139 0.281
regulation of developmental process GO:0050793 684 0.279
positive regulation of vulval development GO:0040026 52 0.279
endocytosis GO:0006897 819 0.277
regulation of transcription dna templated GO:0006355 164 0.276
Human
positive regulation of metabolic process GO:0009893 187 0.273
Human
regulation of nematode larval development GO:0061062 260 0.265
vesicle mediated transport GO:0016192 852 0.257
aromatic compound biosynthetic process GO:0019438 192 0.256
Human
positive regulation of cellular process GO:0048522 332 0.253
Human
regulation of multicellular organismal development GO:2000026 317 0.252
positive regulation of rna metabolic process GO:0051254 103 0.247
Human
nucleobase containing compound biosynthetic process GO:0034654 184 0.246
Human
germ cell development GO:0007281 351 0.239
negative regulation of gene expression GO:0010629 217 0.237
Human
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.212
Human
intracellular receptor signaling pathway GO:0030522 2 0.212
Human
multicellular organismal aging GO:0010259 812 0.210
negative regulation of nematode larval development GO:0061064 208 0.210
cell development GO:0048468 696 0.203
positive regulation of biosynthetic process GO:0009891 109 0.200
Human
negative regulation of cellular process GO:0048523 239 0.199
Human
regulation of biosynthetic process GO:0009889 189 0.199
Human
negative regulation of post embryonic development GO:0048581 208 0.196
cell projection organization GO:0030030 231 0.196
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.189
Human
negative regulation of metabolic process GO:0009892 240 0.186
Human
organelle organization GO:0006996 783 0.184
Human
macromolecule modification GO:0043412 218 0.181
Human
regulation of post embryonic development GO:0048580 260 0.176
single organism organelle organization GO:1902589 501 0.176
Human
ribonucleoprotein complex assembly GO:0022618 4 0.176
determination of adult lifespan GO:0008340 812 0.175
positive regulation of developmental process GO:0051094 408 0.172
positive regulation of post embryonic development GO:0048582 54 0.170
dna templated transcription elongation GO:0006354 1 0.158
negative regulation of biological process GO:0048519 567 0.156
Human
body morphogenesis GO:0010171 620 0.155
positive regulation of nucleic acid templated transcription GO:1903508 102 0.151
Human
positive regulation of cellular metabolic process GO:0031325 178 0.150
Human
macromolecular complex subunit organization GO:0043933 320 0.148
Human
post embryonic development GO:0009791 2152 0.148
phosphorus metabolic process GO:0006793 232 0.148
mitotic spindle organization GO:0007052 81 0.148
negative regulation of developmental process GO:0051093 227 0.146
cellular macromolecule biosynthetic process GO:0034645 247 0.145
Human
neuron projection guidance GO:0097485 82 0.142
mitotic nuclear division GO:0007067 89 0.141
chromatin modification GO:0016568 32 0.139
Human
neuron differentiation GO:0030182 217 0.139
molting cycle GO:0042303 281 0.139
cellular protein modification process GO:0006464 207 0.133
Human
macromolecule localization GO:0033036 771 0.132
negative regulation of macromolecule metabolic process GO:0010605 229 0.125
Human
single organism signaling GO:0044700 401 0.121
Human
axon development GO:0061564 163 0.120
embryonic morphogenesis GO:0048598 152 0.119
negative regulation of multicellular organismal process GO:0051241 236 0.117
neuron development GO:0048666 199 0.117
cell projection morphogenesis GO:0048858 148 0.117
oogenesis GO:0048477 229 0.115
dna metabolic process GO:0006259 74 0.111
cellular component morphogenesis GO:0032989 318 0.110
apoptotic process GO:0006915 478 0.108
Human
generation of neurons GO:0048699 235 0.108
rna processing GO:0006396 34 0.108
Human
regulation of biological quality GO:0065008 741 0.108
Human
purine ribonucleoside catabolic process GO:0046130 75 0.107
organic substance biosynthetic process GO:1901576 323 0.105
Human
cellular component biogenesis GO:0044085 297 0.100
negative regulation of rna metabolic process GO:0051253 53 0.099
Human
tissue development GO:0009888 112 0.097
aging GO:0007568 812 0.096
tube morphogenesis GO:0035239 79 0.095
positive regulation of transcription dna templated GO:0045893 102 0.094
Human
cell part morphogenesis GO:0032990 152 0.094
multi multicellular organism process GO:0044706 390 0.093
regulation of cell cycle process GO:0010564 145 0.092
mrna metabolic process GO:0016071 31 0.092
Human
phosphate containing compound metabolic process GO:0006796 232 0.092
protein metabolic process GO:0019538 422 0.091
Human
cellular nitrogen compound biosynthetic process GO:0044271 192 0.089
Human
negative regulation of cellular biosynthetic process GO:0031327 65 0.089
Human
cellular component movement GO:0006928 388 0.088
organic substance catabolic process GO:1901575 294 0.086
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.086
positive regulation of nematode larval development GO:0061063 54 0.086
developmental growth GO:0048589 412 0.085
negative regulation of transcription dna templated GO:0045892 53 0.082
Human
chromatin remodeling GO:0006338 2 0.081
cell division GO:0051301 262 0.081
organelle localization GO:0051640 127 0.080
female gamete generation GO:0007292 254 0.079
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.078
Human
multi organism reproductive process GO:0044703 867 0.077
growth GO:0040007 562 0.076
rna localization GO:0006403 3 0.076
death GO:0016265 547 0.076
Human
taxis GO:0042330 128 0.076
nervous system development GO:0007399 253 0.073
maintenance of location GO:0051235 580 0.071
cytoskeleton organization GO:0007010 339 0.070
regulation of growth GO:0040008 409 0.069
protein complex assembly GO:0006461 186 0.067
chromatin assembly or disassembly GO:0006333 1 0.066
cellular response to stress GO:0033554 162 0.065
Human
negative regulation of nucleic acid templated transcription GO:1903507 53 0.065
Human
dna duplex unwinding GO:0032508 3 0.064
response to wounding GO:0009611 4 0.062
synaptic transmission GO:0007268 106 0.062
positive regulation of multicellular organism growth GO:0040018 352 0.061
signaling GO:0023052 401 0.060
Human
lipid localization GO:0010876 573 0.059
cell proliferation GO:0008283 116 0.059
lipid storage GO:0019915 565 0.059
multicellular organism growth GO:0035264 385 0.059
multicellular organismal reproductive behavior GO:0033057 384 0.058
positive regulation of neurogenesis GO:0050769 4 0.058
head development GO:0060322 1 0.057
signal transduction GO:0007165 317 0.057
Human
purine nucleoside metabolic process GO:0042278 92 0.057
negative regulation of gene expression epigenetic GO:0045814 2 0.057
neuron projection morphogenesis GO:0048812 114 0.057
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.057
organ morphogenesis GO:0009887 67 0.056
microtubule based process GO:0007017 182 0.055
regulation of localization GO:0032879 194 0.055
cell morphogenesis GO:0000902 163 0.055
multi organism behavior GO:0051705 389 0.054
negative regulation of biosynthetic process GO:0009890 65 0.054
Human
regulation of cell death GO:0010941 65 0.054
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.054
Human
cellular component assembly GO:0022607 293 0.053
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.053
Human
single organism catabolic process GO:0044712 129 0.052
regeneration GO:0031099 4 0.052
organonitrogen compound catabolic process GO:1901565 90 0.051
axonogenesis GO:0007409 102 0.051
oviposition GO:0018991 364 0.051
response to chemical GO:0042221 356 0.050
Human
behavior GO:0007610 527 0.049
muscle tissue development GO:0060537 1 0.049
negative regulation of cell cycle GO:0045786 53 0.049
single organism transport GO:0044765 447 0.048
ribonucleoside monophosphate metabolic process GO:0009161 45 0.048
regulation of multicellular organism growth GO:0040014 373 0.047
catabolic process GO:0009056 318 0.047
regulation of protein localization GO:0032880 50 0.047
histone modification GO:0016570 30 0.047
Human
regulation of intracellular signal transduction GO:1902531 77 0.047
negative regulation of cellular metabolic process GO:0031324 95 0.047
Human
cell migration GO:0016477 306 0.047
transcription elongation from rna polymerase ii promoter GO:0006368 1 0.046
pattern specification process GO:0007389 59 0.046
skin development GO:0043588 24 0.045
regulation of meiotic cell cycle GO:0051445 136 0.045
phosphorylation GO:0016310 116 0.044
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.044
Human
epidermis development GO:0008544 24 0.043
post embryonic organ development GO:0048569 336 0.042
spindle organization GO:0007051 92 0.042
epithelial tube morphogenesis GO:0060562 1 0.041
response to external stimulus GO:0009605 289 0.041
Human
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.041
Human
cellular macromolecular complex assembly GO:0034622 184 0.040
cell death GO:0008219 547 0.040
Human
digestive tract morphogenesis GO:0048546 76 0.040
macromolecule catabolic process GO:0009057 202 0.039
positive regulation of growth GO:0045927 369 0.038
regulation of developmental growth GO:0048638 389 0.038
organonitrogen compound metabolic process GO:1901564 151 0.037
programmed cell death GO:0012501 500 0.037
Human
protein modification process GO:0036211 207 0.037
Human
rna splicing GO:0008380 8 0.037
Human
cuticle development GO:0042335 100 0.036
localization of cell GO:0051674 313 0.036
intracellular signal transduction GO:0035556 96 0.035
Human
reproductive behavior GO:0019098 387 0.035
nucleoside phosphate catabolic process GO:1901292 77 0.035
oxoacid metabolic process GO:0043436 47 0.034
multi organism reproductive behavior GO:0044705 387 0.034
chromosome organization GO:0051276 104 0.034
Human
regulation of locomotion GO:0040012 161 0.034
regulation of cell differentiation GO:0045595 81 0.033
posttranscriptional regulation of gene expression GO:0010608 166 0.033
positive regulation of cell differentiation GO:0045597 8 0.032
regulation of meiosis GO:0040020 94 0.032
organelle assembly GO:0070925 214 0.031
nucleotide catabolic process GO:0009166 77 0.031
cell morphogenesis involved in differentiation GO:0000904 112 0.031
digestive system development GO:0055123 122 0.030
ion transport GO:0006811 113 0.030
cellular nitrogen compound catabolic process GO:0044270 119 0.029
macromolecular complex assembly GO:0065003 193 0.029
aromatic compound catabolic process GO:0019439 116 0.029
heterocycle catabolic process GO:0046700 119 0.029
mrna processing GO:0006397 13 0.029
Human
response to abiotic stimulus GO:0009628 152 0.029
regionalization GO:0003002 31 0.029
inductive cell migration GO:0040039 145 0.028
positive regulation of developmental growth GO:0048639 354 0.028
purine containing compound catabolic process GO:0072523 75 0.028
neuron recognition GO:0008038 83 0.027
single organism localization GO:1902578 518 0.027
dendrite development GO:0016358 42 0.027
regulation of cell proliferation GO:0042127 105 0.027
response to endoplasmic reticulum stress GO:0034976 71 0.027
purine ribonucleoside monophosphate catabolic process GO:0009169 28 0.026
small molecule metabolic process GO:0044281 186 0.026
single organism behavior GO:0044708 83 0.026
regulation of cell development GO:0060284 49 0.026
response to heat GO:0009408 50 0.025
carboxylic acid metabolic process GO:0019752 34 0.025
cellular catabolic process GO:0044248 199 0.025
rna splicing via transesterification reactions GO:0000375 8 0.025
Human
negative regulation of response to stimulus GO:0048585 73 0.025
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.024
nucleotide metabolic process GO:0009117 108 0.024
chemotaxis GO:0006935 120 0.024
regulation of cell division GO:0051302 142 0.023
system process GO:0003008 136 0.023
protein phosphorylation GO:0006468 85 0.022
nucleobase containing compound catabolic process GO:0034655 114 0.022
organic substance transport GO:0071702 113 0.022
regulation of apoptotic process GO:0042981 36 0.022
digestive tract development GO:0048565 122 0.022
ribonucleoside triphosphate metabolic process GO:0009199 87 0.022
ribonucleotide metabolic process GO:0009259 99 0.022
muscle structure development GO:0061061 191 0.022
axon guidance GO:0007411 82 0.022
protein complex subunit organization GO:0071822 280 0.022
chromatin assembly GO:0031497 1 0.022
nucleoside catabolic process GO:0009164 78 0.021
cell cell signaling GO:0007267 118 0.021
organic cyclic compound catabolic process GO:1901361 119 0.021
regulation of nucleocytoplasmic transport GO:0046822 3 0.021
regulation of nervous system development GO:0051960 41 0.020
establishment of organelle localization GO:0051656 123 0.020
regulation of response to stimulus GO:0048583 243 0.020
Human
regulation of signaling GO:0023051 172 0.020
Human
purine nucleoside triphosphate catabolic process GO:0009146 72 0.020
embryonic body morphogenesis GO:0010172 49 0.020
chromosome segregation GO:0007059 180 0.020
gene silencing GO:0016458 143 0.020
cell motility GO:0048870 313 0.019
regulation of protein metabolic process GO:0051246 81 0.019
Human
atp metabolic process GO:0046034 42 0.019
organic acid metabolic process GO:0006082 47 0.019
protein complex biogenesis GO:0070271 186 0.019
regulation of cellular protein metabolic process GO:0032268 75 0.018
Human
negative regulation of signal transduction GO:0009968 60 0.018
purine nucleoside monophosphate metabolic process GO:0009126 43 0.018
single organism biosynthetic process GO:0044711 91 0.018
regulation of programmed cell death GO:0043067 50 0.017
spermatogenesis GO:0007283 41 0.017
atp catabolic process GO:0006200 27 0.017
tube development GO:0035295 126 0.017
nucleobase containing small molecule metabolic process GO:0055086 115 0.017
regulation of apoptotic signaling pathway GO:2001233 1 0.017
male sex differentiation GO:0046661 86 0.017
purine nucleoside catabolic process GO:0006152 75 0.017
response to external biotic stimulus GO:0043207 101 0.016
male gamete generation GO:0048232 41 0.016
positive regulation of cell cycle GO:0045787 55 0.016
sensory organ morphogenesis GO:0090596 2 0.016
purine nucleoside triphosphate metabolic process GO:0009144 87 0.016
cellular amino acid metabolic process GO:0006520 15 0.015
purine containing compound metabolic process GO:0072521 95 0.015
positive regulation of cellular component organization GO:0051130 34 0.015
Human
cellular ketone metabolic process GO:0042180 14 0.015
nucleoside triphosphate catabolic process GO:0009143 72 0.015
negative regulation of rna biosynthetic process GO:1902679 53 0.015
Human
regulation of neurogenesis GO:0050767 40 0.015
glycosyl compound metabolic process GO:1901657 100 0.015
protein oligomerization GO:0051259 4 0.015
negative regulation of mitotic cell cycle GO:0045930 42 0.014
nucleoside monophosphate metabolic process GO:0009123 46 0.014
protein modification by small protein conjugation or removal GO:0070647 40 0.014
regulation of cellular amine metabolic process GO:0033238 0 0.014
transcription initiation from rna polymerase ii promoter GO:0006367 2 0.014
peptidyl amino acid modification GO:0018193 58 0.014
germ line stem cell division GO:0042078 9 0.014
cellular protein metabolic process GO:0044267 279 0.014
Human
ribonucleoside catabolic process GO:0042454 77 0.014
carbohydrate derivative metabolic process GO:1901135 141 0.014
purine nucleoside monophosphate catabolic process GO:0009128 28 0.014
transmembrane transport GO:0055085 110 0.014
anatomical structure formation involved in morphogenesis GO:0048646 250 0.014
establishment of localization in cell GO:0051649 318 0.014
regulation of chromatin modification GO:1903308 2 0.013
Human
rna transport GO:0050658 3 0.013
pigmentation GO:0043473 2 0.013
cellular response to organic substance GO:0071310 119 0.013
Human
protein localization GO:0008104 205 0.013
dna repair GO:0006281 23 0.013
regulation of epithelial cell differentiation GO:0030856 4 0.013
regulation of cell communication GO:0010646 176 0.013
Human
response to drug GO:0042493 14 0.013
regulation of mitotic metaphase anaphase transition GO:0030071 5 0.013
regulation of dna replication GO:0006275 5 0.013
posttranscriptional gene silencing GO:0016441 143 0.013
regulation of cellular component organization GO:0051128 248 0.012
Human
regulation of gene expression epigenetic GO:0040029 163 0.012
purine ribonucleotide metabolic process GO:0009150 95 0.012
negative regulation of signaling GO:0023057 61 0.012
rna interference GO:0016246 137 0.012
internal peptidyl lysine acetylation GO:0018393 3 0.012
cell fate commitment GO:0045165 139 0.012
ribonucleotide catabolic process GO:0009261 75 0.012
cellular localization GO:0051641 360 0.012
regulation of catalytic activity GO:0050790 78 0.012
gene silencing by rna GO:0031047 143 0.012
regulation of mitotic cell cycle embryonic GO:0009794 5 0.012
regulation of stem cell differentiation GO:2000736 1 0.012
negative regulation of neurogenesis GO:0050768 4 0.012
mrna splicing via spliceosome GO:0000398 8 0.012
Human
regulation of cellular ketone metabolic process GO:0010565 3 0.012
rrna metabolic process GO:0016072 3 0.012
meiosis i GO:0007127 19 0.012
striated muscle cell differentiation GO:0051146 158 0.012
regulation of chromosome segregation GO:0051983 20 0.012
cell surface receptor signaling pathway GO:0007166 149 0.012
Human
establishment of rna localization GO:0051236 3 0.011
ribose phosphate metabolic process GO:0019693 99 0.011
axonal fasciculation GO:0007413 79 0.011
nucleoside phosphate metabolic process GO:0006753 108 0.011
response to temperature stimulus GO:0009266 66 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 43 0.011
glycosyl compound catabolic process GO:1901658 79 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.011
posttranscriptional gene silencing by rna GO:0035194 143 0.011
protein catabolic process GO:0030163 162 0.011
regulation of protein stability GO:0031647 3 0.011
regulation of lipid metabolic process GO:0019216 4 0.011
cellular response to chemical stimulus GO:0070887 129 0.011
Human
regulation of protein import into nucleus GO:0042306 3 0.011
regulation of cytoplasmic transport GO:1903649 3 0.011
nucleic acid transport GO:0050657 3 0.011
amine metabolic process GO:0009308 15 0.010
regulation of cellular amino acid metabolic process GO:0006521 0 0.010
regulation of signal transduction GO:0009966 135 0.010
Human
purine ribonucleotide catabolic process GO:0009154 75 0.010
mitotic sister chromatid segregation GO:0000070 38 0.010
nucleoside triphosphate metabolic process GO:0009141 87 0.010
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 2 0.010
regulation of response to stress GO:0080134 28 0.010

skp-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.024
disease of cellular proliferation DOID:14566 0 0.024
organ system cancer DOID:0050686 0 0.024