Caenorhabditis elegans

23 known processes

mcm-3 (CELE_C25D7.6)

Protein MCM-3

mcm-3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.830
embryo development ending in birth or egg hatching GO:0009792 2992 0.778
organelle fission GO:0048285 363 0.674
dna conformation change GO:0071103 11 0.524
Fly
positive regulation of mitotic sister chromatid separation GO:1901970 1 0.500
meiotic nuclear division GO:0007126 300 0.481
chromosome organization GO:0051276 104 0.448
endocytosis GO:0006897 819 0.448
attachment of spindle microtubules to kinetochore GO:0008608 8 0.433
transport GO:0006810 1093 0.424
chromosome segregation GO:0007059 180 0.416
regulation of transcription dna templated GO:0006355 164 0.390
microtubule based process GO:0007017 182 0.384
dna duplex unwinding GO:0032508 3 0.363
Fly
regulation of macromolecule metabolic process GO:0060255 421 0.362
cell cycle GO:0007049 526 0.343
Fly
multicellular organism reproduction GO:0032504 819 0.331
cellular nitrogen compound biosynthetic process GO:0044271 192 0.328
organic substance biosynthetic process GO:1901576 323 0.297
female gamete generation GO:0007292 254 0.295
multicellular organismal reproductive process GO:0048609 815 0.265
meiotic cell cycle process GO:1903046 170 0.261
regulation of macromolecule biosynthetic process GO:0010556 189 0.256
regulation of chromosome organization GO:0033044 20 0.250
developmental process involved in reproduction GO:0003006 1165 0.245
nucleic acid metabolic process GO:0090304 299 0.231
Fly
heterocycle biosynthetic process GO:0018130 187 0.230
organelle organization GO:0006996 783 0.224
organic cyclic compound biosynthetic process GO:1901362 195 0.220
positive regulation of macromolecule metabolic process GO:0010604 149 0.210
cell migration GO:0016477 306 0.207
reproductive system development GO:0061458 850 0.207
locomotion GO:0040011 1634 0.207
nucleobase containing compound biosynthetic process GO:0034654 184 0.200
rna metabolic process GO:0016070 228 0.200
pronuclear migration GO:0035046 51 0.199
regulation of rna metabolic process GO:0051252 173 0.198
sex differentiation GO:0007548 909 0.198
multi organism reproductive process GO:0044703 867 0.197
single organism reproductive process GO:0044702 1196 0.193
maintenance of protein location in cell GO:0032507 12 0.184
neurogenesis GO:0022008 236 0.181
Fly
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.173
receptor mediated endocytosis GO:0006898 715 0.172
cell cycle process GO:0022402 482 0.169
Fly
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.165
dna packaging GO:0006323 7 0.160
chromatin assembly or disassembly GO:0006333 1 0.157
aromatic compound biosynthetic process GO:0019438 192 0.151
regulation of nucleic acid templated transcription GO:1903506 165 0.148
dna geometric change GO:0032392 3 0.147
Fly
phosphate containing compound metabolic process GO:0006796 232 0.144
cell motility GO:0048870 313 0.142
gene expression GO:0010467 412 0.141
regulation of metabolic process GO:0019222 478 0.138
regulation of vulval development GO:0040028 248 0.136
oogenesis GO:0048477 229 0.136
macromolecular complex subunit organization GO:0043933 320 0.133
meiotic cell cycle GO:0051321 335 0.130
negative regulation of biological process GO:0048519 567 0.130
Fly
biosynthetic process GO:0009058 323 0.129
inductive cell migration GO:0040039 145 0.127
cellular biosynthetic process GO:0044249 315 0.125
nervous system development GO:0007399 253 0.124
Fly
sexual reproduction GO:0019953 546 0.123
regulation of multicellular organismal process GO:0051239 726 0.121
genitalia development GO:0048806 741 0.119
positive regulation of chromosome segregation GO:0051984 1 0.118
establishment of nucleus localization GO:0040023 55 0.116
nucleobase containing compound metabolic process GO:0006139 406 0.115
Fly
single fertilization GO:0007338 61 0.112
macromolecule catabolic process GO:0009057 202 0.112
negative regulation of vulval development GO:0040027 206 0.111
macromolecule localization GO:0033036 771 0.111
germ cell development GO:0007281 351 0.110
regulation of primary metabolic process GO:0080090 292 0.109
regulation of cellular biosynthetic process GO:0031326 189 0.105
vesicle mediated transport GO:0016192 852 0.103
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.100
negative regulation of gene expression epigenetic GO:0045814 2 0.098
cell development GO:0048468 696 0.098
positive regulation of cellular process GO:0048522 332 0.098
regulation of gene expression GO:0010468 366 0.096
regulation of mitotic spindle organization GO:0060236 3 0.094
transcription from rna polymerase ii promoter GO:0006366 149 0.094
cellular macromolecule biosynthetic process GO:0034645 247 0.094
generation of neurons GO:0048699 235 0.092
development of primary sexual characteristics GO:0045137 840 0.092
organic cyclic compound catabolic process GO:1901361 119 0.092
phosphorus metabolic process GO:0006793 232 0.091
organophosphate metabolic process GO:0019637 125 0.091
macromolecular complex assembly GO:0065003 193 0.091
regulation of mitotic cell cycle GO:0007346 76 0.091
Fly
microtubule cytoskeleton organization involved in mitosis GO:1902850 12 0.090
nucleic acid templated transcription GO:0097659 169 0.089
hermaphrodite genitalia development GO:0040035 734 0.087
positive regulation of biosynthetic process GO:0009891 109 0.086
positive regulation of multicellular organismal process GO:0051240 417 0.085
dna metabolic process GO:0006259 74 0.085
Fly
negative regulation of nematode larval development GO:0061064 208 0.084
determination of adult lifespan GO:0008340 812 0.083
ovulation GO:0030728 33 0.083
regulation of biological quality GO:0065008 741 0.083
cell projection organization GO:0030030 231 0.082
single organism organelle organization GO:1902589 501 0.081
response to external stimulus GO:0009605 289 0.081
cytoskeleton organization GO:0007010 339 0.079
regulation of cellular metabolic process GO:0031323 305 0.078
neuron differentiation GO:0030182 217 0.077
growth GO:0040007 562 0.075
regulation of nitrogen compound metabolic process GO:0051171 222 0.075
regulation of mitotic sister chromatid segregation GO:0033047 16 0.075
response to chemical GO:0042221 356 0.075
glycosyl compound metabolic process GO:1901657 100 0.074
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.072
macromolecule biosynthetic process GO:0009059 250 0.072
cellular component movement GO:0006928 388 0.071
regulation of gene expression epigenetic GO:0040029 163 0.071
rna biosynthetic process GO:0032774 169 0.071
positive regulation of cellular metabolic process GO:0031325 178 0.070
gamete generation GO:0007276 461 0.070
multicellular organismal reproductive behavior GO:0033057 384 0.069
cellular component biogenesis GO:0044085 297 0.069
gonad development GO:0008406 840 0.069
establishment of organelle localization GO:0051656 123 0.069
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.068
post embryonic development GO:0009791 2152 0.068
cell death GO:0008219 547 0.068
maintenance of location GO:0051235 580 0.068
post embryonic organ development GO:0048569 336 0.067
multi organism behavior GO:0051705 389 0.067
neuron projection development GO:0031175 187 0.066
negative regulation of metabolic process GO:0009892 240 0.066
negative regulation of post embryonic development GO:0048581 208 0.065
apoptotic process GO:0006915 478 0.065
nucleoside monophosphate metabolic process GO:0009123 46 0.065
lipid localization GO:0010876 573 0.064
positive regulation of developmental process GO:0051094 408 0.063
fertilization GO:0009566 63 0.063
lipid storage GO:0019915 565 0.063
transcription dna templated GO:0006351 168 0.063
catabolic process GO:0009056 318 0.062
regulation of biosynthetic process GO:0009889 189 0.061
reproductive structure development GO:0048608 850 0.061
regulation of mitosis GO:0007088 18 0.059
aging GO:0007568 812 0.059
organ development GO:0048513 1102 0.058
chromosome condensation GO:0030261 6 0.057
regulation of rna biosynthetic process GO:2001141 165 0.057
nucleus localization GO:0051647 55 0.056
oocyte development GO:0048599 44 0.056
localization of cell GO:0051674 313 0.055
posttranscriptional regulation of gene expression GO:0010608 166 0.055
regulation of nematode larval development GO:0061062 260 0.055
protein complex subunit organization GO:0071822 280 0.055
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.054
establishment of localization GO:0051234 1171 0.054
single organism catabolic process GO:0044712 129 0.054
multi multicellular organism process GO:0044706 390 0.054
oocyte differentiation GO:0009994 45 0.053
ribonucleoside monophosphate metabolic process GO:0009161 45 0.053
mitotic nuclear division GO:0007067 89 0.052
small molecule metabolic process GO:0044281 186 0.051
regulation of multicellular organism growth GO:0040014 373 0.051
regulation of organelle organization GO:0033043 164 0.051
cellular component assembly GO:0022607 293 0.050
chromatin remodeling GO:0006338 2 0.048
positive regulation of metabolic process GO:0009893 187 0.048
metaphase anaphase transition of mitotic cell cycle GO:0007091 10 0.048
regulation of post embryonic development GO:0048580 260 0.048
negative regulation of developmental process GO:0051093 227 0.048
vulval development GO:0040025 333 0.047
regulation of developmental process GO:0050793 684 0.046
multicellular organism growth GO:0035264 385 0.046
aromatic compound catabolic process GO:0019439 116 0.046
oviposition GO:0018991 364 0.045
female meiotic division GO:0007143 17 0.045
nucleobase containing compound catabolic process GO:0034655 114 0.045
cellular response to stress GO:0033554 162 0.044
Fly
meiotic chromosome segregation GO:0045132 139 0.044
positive regulation of growth GO:0045927 369 0.044
multi organism reproductive behavior GO:0044705 387 0.044
multicellular organismal aging GO:0010259 812 0.044
organic substance catabolic process GO:1901575 294 0.043
positive regulation of cellular component organization GO:0051130 34 0.043
regulation of meiotic cell cycle GO:0051445 136 0.043
cellular response to dna damage stimulus GO:0006974 41 0.043
Fly
single organism localization GO:1902578 518 0.043
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.043
cellular catabolic process GO:0044248 199 0.043
regulation of cellular component organization GO:0051128 248 0.042
cellular nitrogen compound catabolic process GO:0044270 119 0.042
cell part morphogenesis GO:0032990 152 0.042
heterocycle catabolic process GO:0046700 119 0.041
purine nucleoside monophosphate metabolic process GO:0009126 43 0.041
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.041
cell cycle phase transition GO:0044770 19 0.040
Fly
regulation of developmental growth GO:0048638 389 0.039
regulation of multicellular organismal development GO:2000026 317 0.039
purine nucleotide metabolic process GO:0006163 95 0.039
organonitrogen compound metabolic process GO:1901564 151 0.039
nuclear migration GO:0007097 54 0.039
reproductive behavior GO:0019098 387 0.038
positive regulation of nucleic acid templated transcription GO:1903508 102 0.038
positive regulation of cellular protein catabolic process GO:1903364 3 0.037
cell projection morphogenesis GO:0048858 148 0.037
regulation of growth GO:0040008 409 0.037
cellular localization GO:0051641 360 0.036
positive regulation of vulval development GO:0040026 52 0.036
cellular macromolecular complex assembly GO:0034622 184 0.036
ribose phosphate metabolic process GO:0019693 99 0.035
neuron development GO:0048666 199 0.035
ribonucleoside triphosphate metabolic process GO:0009199 87 0.035
purine ribonucleoside catabolic process GO:0046130 75 0.034
positive regulation of developmental growth GO:0048639 354 0.033
single organism biosynthetic process GO:0044711 91 0.033
nucleoside triphosphate metabolic process GO:0009141 87 0.033
nucleus organization GO:0006997 38 0.032
regulation of chromosome segregation GO:0051983 20 0.032
purine nucleoside triphosphate metabolic process GO:0009144 87 0.032
developmental growth GO:0048589 412 0.032
negative regulation of gene expression GO:0010629 217 0.032
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.032
regulation of cell division GO:0051302 142 0.031
regulation of multi organism process GO:0043900 69 0.031
protein catabolic process GO:0030163 162 0.031
posttranscriptional gene silencing by rna GO:0035194 143 0.031
positive regulation of molecular function GO:0044093 61 0.031
programmed cell death GO:0012501 500 0.031
gene silencing GO:0016458 143 0.031
regulation of cell cycle process GO:0010564 145 0.031
Fly
attachment of mitotic spindle microtubules to kinetochore GO:0051315 6 0.030
atp metabolic process GO:0046034 42 0.029
establishment of mitotic spindle orientation GO:0000132 28 0.029
purine ribonucleoside monophosphate metabolic process GO:0009167 43 0.028
regulation of protein metabolic process GO:0051246 81 0.028
death GO:0016265 547 0.028
nucleotide metabolic process GO:0009117 108 0.028
purine containing compound metabolic process GO:0072521 95 0.028
positive regulation of nematode larval development GO:0061063 54 0.027
protein complex biogenesis GO:0070271 186 0.027
organonitrogen compound catabolic process GO:1901565 90 0.027
chromatin organization GO:0006325 32 0.027
chromatin assembly GO:0031497 1 0.027
regulation of behavior GO:0050795 97 0.027
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.027
purine containing compound catabolic process GO:0072523 75 0.027
cell division GO:0051301 262 0.027
cytokinesis GO:0000910 80 0.026
meiosis i GO:0007127 19 0.026
mitotic sister chromatid segregation GO:0000070 38 0.025
purine nucleoside metabolic process GO:0042278 92 0.025
regulation of cellular catabolic process GO:0031329 51 0.025
mitotic sister chromatid separation GO:0051306 13 0.025
positive regulation of rna metabolic process GO:0051254 103 0.025
negative regulation of cell cycle GO:0045786 53 0.024
Fly
purine ribonucleotide metabolic process GO:0009150 95 0.024
ribonucleoside metabolic process GO:0009119 98 0.024
oocyte construction GO:0007308 2 0.024
regulation of nuclear division GO:0051783 115 0.024
ribonucleotide metabolic process GO:0009259 99 0.024
organelle localization GO:0051640 127 0.024
body morphogenesis GO:0010171 620 0.024
metaphase anaphase transition of cell cycle GO:0044784 15 0.023
nucleoside metabolic process GO:0009116 99 0.023
signal transduction GO:0007165 317 0.023
cellular protein metabolic process GO:0044267 279 0.023
gene silencing by rna GO:0031047 143 0.023
nucleoside triphosphate catabolic process GO:0009143 72 0.023
positive regulation of chromosome organization GO:2001252 2 0.023
male sex differentiation GO:0046661 86 0.022
mitotic chromosome condensation GO:0007076 3 0.022
germ line stem cell division GO:0042078 9 0.022
purine ribonucleoside metabolic process GO:0046128 92 0.022
mitotic g2 m transition checkpoint GO:0044818 1 0.021
Fly
positive regulation of proteasomal protein catabolic process GO:1901800 1 0.021
cuticle development GO:0042335 100 0.021
nucleobase containing small molecule metabolic process GO:0055086 115 0.021
protein localization GO:0008104 205 0.021
carbohydrate derivative catabolic process GO:1901136 82 0.021
neuron projection morphogenesis GO:0048812 114 0.020
molting cycle GO:0042303 281 0.020
positive regulation of cellular catabolic process GO:0031331 35 0.020
behavior GO:0007610 527 0.020
nucleoside phosphate metabolic process GO:0006753 108 0.020
mitotic spindle stabilization GO:0043148 2 0.020
regulation of protein ubiquitination GO:0031396 3 0.019
mitotic cell cycle process GO:1903047 194 0.019
Fly
negative regulation of biosynthetic process GO:0009890 65 0.019
sister chromatid segregation GO:0000819 46 0.018
glycosyl compound catabolic process GO:1901658 79 0.018
positive regulation of post embryonic development GO:0048582 54 0.018
protein metabolic process GO:0019538 422 0.018
dna topological change GO:0006265 1 0.018
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.018
establishment of spindle localization GO:0051293 51 0.017
cell proliferation GO:0008283 116 0.017
head development GO:0060322 1 0.017
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.017
mitotic spindle organization GO:0007052 81 0.017
carbohydrate derivative metabolic process GO:1901135 141 0.017
modification dependent macromolecule catabolic process GO:0043632 32 0.017
cellular protein complex assembly GO:0043623 178 0.017
negative regulation of cellular metabolic process GO:0031324 95 0.017
regulation of cell differentiation GO:0045595 81 0.017
axon development GO:0061564 163 0.017
posttranscriptional gene silencing GO:0016441 143 0.016
regulation of cellular amine metabolic process GO:0033238 0 0.016
regulation of mitotic metaphase anaphase transition GO:0030071 5 0.016
maintenance of location in cell GO:0051651 12 0.016
regulation of response to stimulus GO:0048583 243 0.016
negative regulation of transcription dna templated GO:0045892 53 0.015
negative regulation of mitotic cell cycle phase transition GO:1901991 5 0.015
Fly
ribonucleoside catabolic process GO:0042454 77 0.015
rna interference GO:0016246 137 0.015
positive regulation of multicellular organism growth GO:0040018 352 0.015
purine nucleoside catabolic process GO:0006152 75 0.015
protein complex assembly GO:0006461 186 0.015
negative regulation of nucleic acid templated transcription GO:1903507 53 0.015
organophosphate catabolic process GO:0046434 81 0.015
internal peptidyl lysine acetylation GO:0018393 3 0.015
spindle checkpoint GO:0031577 4 0.015
cellular macromolecule catabolic process GO:0044265 73 0.015
phosphorylation GO:0016310 116 0.015
establishment of localization in cell GO:0051649 318 0.015
negative regulation of multicellular organismal process GO:0051241 236 0.015
muscle structure development GO:0061061 191 0.015
negative regulation of neurogenesis GO:0050768 4 0.015
purine nucleotide catabolic process GO:0006195 75 0.015
cell cell signaling GO:0007267 118 0.014
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 1 0.014
positive regulation of cell cycle GO:0045787 55 0.014
cellular protein catabolic process GO:0044257 37 0.014
regulation of cellular ketone metabolic process GO:0010565 3 0.014
negative regulation of macromolecule metabolic process GO:0010605 229 0.014
regulation of molecular function GO:0065009 89 0.014
cell morphogenesis involved in differentiation GO:0000904 112 0.014
anatomical structure formation involved in morphogenesis GO:0048646 250 0.013
ribonucleoprotein complex assembly GO:0022618 4 0.013
chromosome separation GO:0051304 19 0.013
regulation of meiosis GO:0040020 94 0.013
membrane organization GO:0061024 135 0.013
establishment of chromosome localization GO:0051303 10 0.013
peptidyl amino acid modification GO:0018193 58 0.013
response to oxidative stress GO:0006979 42 0.013
nematode male tail tip morphogenesis GO:0045138 77 0.013
chromosome localization GO:0050000 10 0.013
establishment or maintenance of cell polarity GO:0007163 63 0.013
positive regulation of transcription dna templated GO:0045893 102 0.013
reciprocal meiotic recombination GO:0007131 11 0.013
regulation of cell proliferation GO:0042127 105 0.013
regulation of protein stability GO:0031647 3 0.013
amine metabolic process GO:0009308 15 0.013
carboxylic acid metabolic process GO:0019752 34 0.013
male gamete generation GO:0048232 41 0.013
regulation of catabolic process GO:0009894 57 0.013
negative regulation of rna metabolic process GO:0051253 53 0.012
taxis GO:0042330 128 0.012
nucleotide catabolic process GO:0009166 77 0.012
positive regulation of rna biosynthetic process GO:1902680 102 0.012
cellular amine metabolic process GO:0044106 15 0.012
digestive tract morphogenesis GO:0048546 76 0.012
positive regulation of catalytic activity GO:0043085 59 0.012
ribonucleoside triphosphate catabolic process GO:0009203 72 0.012
oocyte axis specification GO:0007309 2 0.012
developmental maturation GO:0021700 26 0.012
dna replication GO:0006260 15 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.012
protein deubiquitination GO:0016579 2 0.012
negative regulation of cellular process GO:0048523 239 0.012
Fly
regulation of helicase activity GO:0051095 2 0.012
organic substance transport GO:0071702 113 0.012
positive regulation of catabolic process GO:0009896 38 0.012
single organism signaling GO:0044700 401 0.011
cellular macromolecule localization GO:0070727 75 0.011
cellular protein modification process GO:0006464 207 0.011
intracellular receptor signaling pathway GO:0030522 2 0.011
digestive system development GO:0055123 122 0.011
negative regulation of mitotic cell cycle GO:0045930 42 0.011
Fly
muscle tissue development GO:0060537 1 0.011
cell cycle g2 m phase transition GO:0044839 1 0.011
cellular component morphogenesis GO:0032989 318 0.011
establishment of mitotic spindle localization GO:0040001 41 0.011
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 2 0.011
phagocytosis engulfment GO:0006911 98 0.011
regulation of catalytic activity GO:0050790 78 0.011
positive regulation of nucleoside metabolic process GO:0045979 28 0.011
positive regulation of protein metabolic process GO:0051247 45 0.011
innate immune response GO:0045087 190 0.011
membrane invagination GO:0010324 98 0.011
nucleic acid transport GO:0050657 3 0.011
positive regulation of protein transport GO:0051222 4 0.011
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 1 0.011
nuclear pore organization GO:0006999 2 0.011
single organism transport GO:0044765 447 0.011
nucleoside catabolic process GO:0009164 78 0.010
regulation of signal transduction GO:0009966 135 0.010
response to inorganic substance GO:0010035 50 0.010
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.010
negative regulation of rna biosynthetic process GO:1902679 53 0.010
protein modification process GO:0036211 207 0.010
cellular amino acid metabolic process GO:0006520 15 0.010
regulation of cellular amino acid metabolic process GO:0006521 0 0.010
negative regulation of mitotic metaphase anaphase transition GO:0045841 4 0.010
metaphase plate congression GO:0051310 5 0.010
skeletal muscle organ development GO:0060538 3 0.010

mcm-3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.013
muscular disease DOID:0080000 0 0.013
disease of anatomical entity DOID:7 0 0.013
musculoskeletal system disease DOID:17 0 0.013
muscle tissue disease DOID:66 0 0.013
nervous system disease DOID:863 0 0.012
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.011