Caenorhabditis elegans

24 known processes

pbs-2 (CELE_C47B2.4)

Protein PBS-2

pbs-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single fertilization GO:0007338 61 0.935
pronuclear migration GO:0035046 51 0.899
fertilization GO:0009566 63 0.761
proteasome assembly GO:0043248 1 0.643
modification dependent protein catabolic process GO:0019941 32 0.589
Yeast
post embryonic development GO:0009791 2152 0.559
mitotic spindle organization GO:0007052 81 0.546
organelle fission GO:0048285 363 0.428
spindle organization GO:0007051 92 0.405
multi organism reproductive process GO:0044703 867 0.356
ubiquitin dependent protein catabolic process GO:0006511 32 0.332
Yeast
regulation of rna biosynthetic process GO:2001141 165 0.330
cellular protein catabolic process GO:0044257 37 0.280
Yeast
microtubule based process GO:0007017 182 0.272
embryo development ending in birth or egg hatching GO:0009792 2992 0.265
organelle organization GO:0006996 783 0.258
sexual reproduction GO:0019953 546 0.245
establishment of localization GO:0051234 1171 0.227
mitotic cell cycle process GO:1903047 194 0.223
single organism organelle organization GO:1902589 501 0.219
mitotic nuclear division GO:0007067 89 0.218
cell cycle GO:0007049 526 0.214
multicellular organismal reproductive process GO:0048609 815 0.207
modification dependent macromolecule catabolic process GO:0043632 32 0.191
Yeast
proteolysis involved in cellular protein catabolic process GO:0051603 32 0.189
Yeast
proteasomal protein catabolic process GO:0010498 20 0.188
Yeast
protein catabolic process GO:0030163 162 0.188
Yeast
body morphogenesis GO:0010171 620 0.180
multicellular organism reproduction GO:0032504 819 0.177
cellular protein metabolic process GO:0044267 279 0.175
Yeast
cytoskeleton organization GO:0007010 339 0.172
death GO:0016265 547 0.171
regulation of transcription dna templated GO:0006355 164 0.168
transport GO:0006810 1093 0.168
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.165
behavior GO:0007610 527 0.164
cell cycle process GO:0022402 482 0.161
proteolysis GO:0006508 61 0.160
Yeast
determination of adult lifespan GO:0008340 812 0.153
spindle assembly GO:0051225 8 0.152
multicellular organismal aging GO:0010259 812 0.149
regulation of gene expression GO:0010468 366 0.146
aging GO:0007568 812 0.146
meiotic cell cycle process GO:1903046 170 0.146
locomotion GO:0040011 1634 0.142
vulval development GO:0040025 333 0.141
establishment of nucleus localization GO:0040023 55 0.138
multi organism reproductive behavior GO:0044705 387 0.135
cellular component assembly GO:0022607 293 0.133
cell death GO:0008219 547 0.128
cellular nitrogen compound biosynthetic process GO:0044271 192 0.123
negative regulation of vulval development GO:0040027 206 0.123
multicellular organism growth GO:0035264 385 0.121
embryo development GO:0009790 3052 0.121
cellular component biogenesis GO:0044085 297 0.121
regulation of biosynthetic process GO:0009889 189 0.121
heterocycle biosynthetic process GO:0018130 187 0.120
negative regulation of biological process GO:0048519 567 0.120
protein complex subunit organization GO:0071822 280 0.120
nucleotide metabolic process GO:0009117 108 0.117
positive regulation of cellular process GO:0048522 332 0.115
apoptotic process GO:0006915 478 0.110
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 20 0.109
Yeast
centrosomal and pronuclear rotation GO:0035047 6 0.108
cell development GO:0048468 696 0.108
regulation of multicellular organismal process GO:0051239 726 0.106
macromolecular complex subunit organization GO:0043933 320 0.105
gene expression GO:0010467 412 0.105
negative regulation of nematode larval development GO:0061064 208 0.104
regulation of macromolecule metabolic process GO:0060255 421 0.100
protein metabolic process GO:0019538 422 0.097
Yeast
receptor mediated endocytosis GO:0006898 715 0.093
regulation of developmental process GO:0050793 684 0.090
developmental growth GO:0048589 412 0.090
regulation of macromolecule biosynthetic process GO:0010556 189 0.089
neurogenesis GO:0022008 236 0.088
nucleic acid templated transcription GO:0097659 169 0.088
vesicle mediated transport GO:0016192 852 0.087
regulation of biological quality GO:0065008 741 0.087
nucleus localization GO:0051647 55 0.086
regulation of growth GO:0040008 409 0.085
multicellular organismal reproductive behavior GO:0033057 384 0.082
regulation of multicellular organism growth GO:0040014 373 0.079
macromolecule localization GO:0033036 771 0.078
single organism reproductive process GO:0044702 1196 0.077
meiotic cell cycle GO:0051321 335 0.076
regulation of developmental growth GO:0048638 389 0.076
single organism localization GO:1902578 518 0.075
positive regulation of multicellular organismal process GO:0051240 417 0.073
protein complex assembly GO:0006461 186 0.072
macromolecule modification GO:0043412 218 0.072
positive regulation of developmental process GO:0051094 408 0.071
meiotic chromosome segregation GO:0045132 139 0.071
taxis GO:0042330 128 0.070
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.069
endocytosis GO:0006897 819 0.068
gamete generation GO:0007276 461 0.067
nuclear migration GO:0007097 54 0.067
lipid localization GO:0010876 573 0.066
oocyte axis specification GO:0007309 2 0.066
regulation of nucleic acid templated transcription GO:1903506 165 0.066
positive regulation of macromolecule metabolic process GO:0010604 149 0.065
neuron projection guidance GO:0097485 82 0.065
macromolecular complex assembly GO:0065003 193 0.065
programmed cell death GO:0012501 500 0.064
transcription dna templated GO:0006351 168 0.064
nervous system development GO:0007399 253 0.063
maintenance of location GO:0051235 580 0.062
positive regulation of multicellular organism growth GO:0040018 352 0.062
cellular protein complex assembly GO:0043623 178 0.061
oocyte construction GO:0007308 2 0.061
localization of cell GO:0051674 313 0.057
positive regulation of growth GO:0045927 369 0.056
inductive cell migration GO:0040039 145 0.055
growth GO:0040007 562 0.055
cellular protein modification process GO:0006464 207 0.053
cell motility GO:0048870 313 0.053
sex differentiation GO:0007548 909 0.053
organelle assembly GO:0070925 214 0.052
cellular biosynthetic process GO:0044249 315 0.052
regulation of rna metabolic process GO:0051252 173 0.052
meiotic nuclear division GO:0007126 300 0.049
pole plasm assembly GO:0007315 2 0.048
lipid storage GO:0019915 565 0.048
nucleobase containing compound biosynthetic process GO:0034654 184 0.048
negative regulation of developmental process GO:0051093 227 0.047
cell migration GO:0016477 306 0.047
positive regulation of transcription dna templated GO:0045893 102 0.046
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.046
positive regulation of developmental growth GO:0048639 354 0.044
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.043
positive regulation of cellular metabolic process GO:0031325 178 0.043
phagocytosis GO:0006909 115 0.042
regulation of epithelial cell proliferation GO:0050678 1 0.042
er associated ubiquitin dependent protein catabolic process GO:0030433 6 0.042
germ cell development GO:0007281 351 0.042
transcription from rna polymerase ii promoter GO:0006366 149 0.040
cellular component morphogenesis GO:0032989 318 0.040
regulation of cellular catabolic process GO:0031329 51 0.039
molting cycle GO:0042303 281 0.039
negative regulation of multicellular organismal process GO:0051241 236 0.038
regulation of nematode larval development GO:0061062 260 0.038
single organism transport GO:0044765 447 0.038
gene silencing GO:0016458 143 0.038
negative regulation of post embryonic development GO:0048581 208 0.038
regulation of primary metabolic process GO:0080090 292 0.037
regulation of cell proliferation GO:0042127 105 0.037
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.037
regulation of cellular metabolic process GO:0031323 305 0.037
catabolic process GO:0009056 318 0.037
Yeast
protein localization GO:0008104 205 0.036
posttranscriptional gene silencing GO:0016441 143 0.035
cell proliferation GO:0008283 116 0.035
engulfment of apoptotic cell GO:0043652 94 0.035
nucleobase containing compound metabolic process GO:0006139 406 0.034
positive regulation of cellular biosynthetic process GO:0031328 109 0.034
organic cyclic compound biosynthetic process GO:1901362 195 0.034
cellular response to stress GO:0033554 162 0.034
Fly
rna biosynthetic process GO:0032774 169 0.034
establishment of localization in cell GO:0051649 318 0.034
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.034
response to wounding GO:0009611 4 0.033
regulation of vulval development GO:0040028 248 0.033
cellular macromolecular complex assembly GO:0034622 184 0.033
development of primary sexual characteristics GO:0045137 840 0.033
cellular catabolic process GO:0044248 199 0.033
Yeast
protein modification by small protein conjugation or removal GO:0070647 40 0.033
neuron differentiation GO:0030182 217 0.033
posttranscriptional regulation of gene expression GO:0010608 166 0.033
regulation of metabolic process GO:0019222 478 0.032
post embryonic organ development GO:0048569 336 0.032
response to abiotic stimulus GO:0009628 152 0.031
regulation of cellular biosynthetic process GO:0031326 189 0.031
positive regulation of rna biosynthetic process GO:1902680 102 0.031
macromolecule catabolic process GO:0009057 202 0.031
Yeast
multi organism behavior GO:0051705 389 0.031
regulation of post embryonic development GO:0048580 260 0.030
phagocytosis engulfment GO:0006911 98 0.030
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.030
protein complex biogenesis GO:0070271 186 0.030
regulation of multicellular organismal development GO:2000026 317 0.030
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.030
gene silencing by rna GO:0031047 143 0.029
cellular component movement GO:0006928 388 0.029
nucleus organization GO:0006997 38 0.029
spindle assembly involved in mitosis GO:0090307 6 0.029
oogenesis GO:0048477 229 0.028
female gamete generation GO:0007292 254 0.028
muscle cell differentiation GO:0042692 171 0.028
muscle structure development GO:0061061 191 0.027
cell projection organization GO:0030030 231 0.027
dna templated transcription initiation GO:0006352 3 0.026
ribonucleoside triphosphate metabolic process GO:0009199 87 0.026
signaling GO:0023052 401 0.026
cellular component assembly involved in morphogenesis GO:0010927 183 0.026
axon guidance GO:0007411 82 0.025
establishment of organelle localization GO:0051656 123 0.025
reproductive system development GO:0061458 850 0.025
rna interference GO:0016246 137 0.025
neuron projection development GO:0031175 187 0.025
dna recombination GO:0006310 19 0.025
rna localization GO:0006403 3 0.024
multi multicellular organism process GO:0044706 390 0.024
male gamete generation GO:0048232 41 0.024
negative regulation of cellular process GO:0048523 239 0.024
regulation of intracellular signal transduction GO:1902531 77 0.024
response to chemical GO:0042221 356 0.023
rna metabolic process GO:0016070 228 0.023
regulation of nitrogen compound metabolic process GO:0051171 222 0.022
gonad development GO:0008406 840 0.022
regulation of response to wounding GO:1903034 1 0.022
regulation of meiotic cell cycle GO:0051445 136 0.022
positive regulation of rna metabolic process GO:0051254 103 0.022
negative regulation of gene expression GO:0010629 217 0.022
developmental process involved in reproduction GO:0003006 1165 0.021
actin filament based process GO:0030029 191 0.021
membrane invagination GO:0010324 98 0.021
chemotaxis GO:0006935 120 0.021
atp metabolic process GO:0046034 42 0.021
regulation of signaling GO:0023051 172 0.021
response to external stimulus GO:0009605 289 0.021
signal transduction GO:0007165 317 0.021
head development GO:0060322 1 0.021
nucleoside triphosphate metabolic process GO:0009141 87 0.021
oviposition GO:0018991 364 0.021
cellular macromolecule catabolic process GO:0044265 73 0.020
Yeast
positive regulation of gene expression GO:0010628 112 0.020
aromatic compound biosynthetic process GO:0019438 192 0.020
ribonucleoside monophosphate metabolic process GO:0009161 45 0.020
reproductive structure development GO:0048608 850 0.019
intracellular receptor signaling pathway GO:0030522 2 0.019
biosynthetic process GO:0009058 323 0.019
microtubule cytoskeleton organization involved in mitosis GO:1902850 12 0.019
neurological system process GO:0050877 53 0.019
regulation of protein metabolic process GO:0051246 81 0.019
regulation of localization GO:0032879 194 0.019
intracellular signal transduction GO:0035556 96 0.019
cellular response to chemical stimulus GO:0070887 129 0.019
nucleoside monophosphate metabolic process GO:0009123 46 0.019
chromosome segregation GO:0007059 180 0.018
transcription initiation from rna polymerase ii promoter GO:0006367 2 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.018
myofibril assembly GO:0030239 154 0.018
cell projection morphogenesis GO:0048858 148 0.018
translation GO:0006412 37 0.017
macromolecule biosynthetic process GO:0009059 250 0.017
striated muscle cell development GO:0055002 157 0.017
response to hermaphrodite contact GO:0034606 10 0.017
positive regulation of cell communication GO:0010647 69 0.017
regulation of gene expression epigenetic GO:0040029 163 0.017
cellular macromolecule biosynthetic process GO:0034645 247 0.017
reproductive behavior GO:0019098 387 0.017
positive regulation of biosynthetic process GO:0009891 109 0.017
protein deubiquitination GO:0016579 2 0.017
cellular response to metal ion GO:0071248 3 0.016
spermatogenesis GO:0007283 41 0.016
striated muscle cell differentiation GO:0051146 158 0.016
axon development GO:0061564 163 0.016
nucleic acid transport GO:0050657 3 0.016
single organism signaling GO:0044700 401 0.016
muscle cell development GO:0055001 158 0.016
membrane organization GO:0061024 135 0.016
anatomical structure formation involved in morphogenesis GO:0048646 250 0.016
actomyosin structure organization GO:0031032 154 0.015
nucleoside triphosphate catabolic process GO:0009143 72 0.015
organonitrogen compound metabolic process GO:1901564 151 0.015
regulation of apoptotic signaling pathway GO:2001233 1 0.015
neuron development GO:0048666 199 0.015
cell maturation GO:0048469 26 0.015
cell division GO:0051301 262 0.015
purine nucleoside catabolic process GO:0006152 75 0.015
translational elongation GO:0006414 1 0.015
posttranscriptional gene silencing by rna GO:0035194 143 0.015
positive regulation of protein metabolic process GO:0051247 45 0.014
system process GO:0003008 136 0.014
regulation of cellular protein metabolic process GO:0032268 75 0.014
positive regulation of protein modification process GO:0031401 29 0.014
organic substance transport GO:0071702 113 0.014
small molecule metabolic process GO:0044281 186 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.014
purine nucleoside monophosphate catabolic process GO:0009128 28 0.014
positive regulation of chromosome organization GO:2001252 2 0.014
axonogenesis GO:0007409 102 0.014
regulation of protein ubiquitination GO:0031396 3 0.014
lamellipodium organization GO:0097581 2 0.014
response to heat GO:0009408 50 0.013
regeneration GO:0031099 4 0.013
myosin filament assembly GO:0031034 138 0.013
cellular localization GO:0051641 360 0.013
detection of external stimulus GO:0009581 4 0.013
organic substance catabolic process GO:1901575 294 0.013
Yeast
cellular nitrogen compound catabolic process GO:0044270 119 0.013
organic substance biosynthetic process GO:1901576 323 0.013
cell cycle switching mitotic to meiotic cell cycle GO:0051728 35 0.013
immune response GO:0006955 192 0.013
organelle localization GO:0051640 127 0.013
organ development GO:0048513 1102 0.013
establishment of rna localization GO:0051236 3 0.013
chromosome organization GO:0051276 104 0.013
positive regulation of nucleic acid templated transcription GO:1903508 102 0.013
positive regulation of intracellular signal transduction GO:1902533 24 0.013
protein modification process GO:0036211 207 0.013
purine nucleoside monophosphate metabolic process GO:0009126 43 0.013
cell morphogenesis involved in differentiation GO:0000904 112 0.012
innate immune response GO:0045087 190 0.012
regulation of response to stimulus GO:0048583 243 0.012
rna transport GO:0050658 3 0.012
nematode male tail tip morphogenesis GO:0045138 77 0.012
ribonucleoprotein complex assembly GO:0022618 4 0.012
regulation of epithelial cell differentiation GO:0030856 4 0.012
positive regulation of transferase activity GO:0051347 21 0.012
detection of abiotic stimulus GO:0009582 4 0.012
mrna splicing via spliceosome GO:0000398 8 0.012
ribose phosphate metabolic process GO:0019693 99 0.012
positive regulation of cellular protein catabolic process GO:1903364 3 0.012
ribonucleoside catabolic process GO:0042454 77 0.012
translational initiation GO:0006413 2 0.011
atp catabolic process GO:0006200 27 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.011
nucleoside phosphate metabolic process GO:0006753 108 0.011
myosin filament organization GO:0031033 138 0.011
apoptotic cell clearance GO:0043277 111 0.011
chromatin organization GO:0006325 32 0.011
actin cytoskeleton organization GO:0030036 184 0.011
hermaphrodite genitalia development GO:0040035 734 0.011
regulation of chromatin modification GO:1903308 2 0.011
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 2 0.011
nucleoside catabolic process GO:0009164 78 0.011
regulation of cellular amine metabolic process GO:0033238 0 0.011
cellular response to dna damage stimulus GO:0006974 41 0.011
Fly
ribonucleoside triphosphate catabolic process GO:0009203 72 0.011
regulation of cellular component organization GO:0051128 248 0.010
phosphate containing compound metabolic process GO:0006796 232 0.010
secretion GO:0046903 147 0.010
covalent chromatin modification GO:0016569 30 0.010
amine metabolic process GO:0009308 15 0.010
negative regulation of macromolecule metabolic process GO:0010605 229 0.010
trna metabolic process GO:0006399 3 0.010

pbs-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.059
nervous system disease DOID:863 0 0.020
neuromuscular disease DOID:440 0 0.016
charcot marie tooth disease type 2 DOID:0050539 0 0.016
charcot marie tooth disease DOID:10595 0 0.016
neuropathy DOID:870 0 0.016