Caenorhabditis elegans

46 known processes

mlc-4 (CELE_C56G7.1)

Protein MLC-4

mlc-4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
locomotion GO:0040011 1634 0.556
Worm Fly
transport GO:0006810 1093 0.332
Fly
embryo development GO:0009790 3052 0.326
establishment of localization GO:0051234 1171 0.302
Fly
embryo development ending in birth or egg hatching GO:0009792 2992 0.291
organelle organization GO:0006996 783 0.281
post embryonic development GO:0009791 2152 0.276
endocytosis GO:0006897 819 0.273
single organism organelle organization GO:1902589 501 0.251
vesicle mediated transport GO:0016192 852 0.219
multicellular organismal reproductive process GO:0048609 815 0.209
Worm Fly
determination of adult lifespan GO:0008340 812 0.193
regulation of response to stimulus GO:0048583 243 0.192
Worm
nervous system development GO:0007399 253 0.188
Fly
developmental process involved in reproduction GO:0003006 1165 0.186
Fly
multicellular organismal aging GO:0010259 812 0.175
cellular component morphogenesis GO:0032989 318 0.170
Fly
gonad development GO:0008406 840 0.165
aging GO:0007568 812 0.160
microtubule based process GO:0007017 182 0.158
neuron development GO:0048666 199 0.155
cell cycle process GO:0022402 482 0.153
reproductive behavior GO:0019098 387 0.148
Worm
sex differentiation GO:0007548 909 0.147
single organism reproductive process GO:0044702 1196 0.140
Fly
receptor mediated endocytosis GO:0006898 715 0.139
axon development GO:0061564 163 0.138
regulation of biological quality GO:0065008 741 0.133
Human Fly
localization of cell GO:0051674 313 0.123
Fly
cell part morphogenesis GO:0032990 152 0.121
multicellular organism reproduction GO:0032504 819 0.119
Worm Fly
regulation of multicellular organismal process GO:0051239 726 0.115
Worm
response to chemical GO:0042221 356 0.113
regulation of developmental process GO:0050793 684 0.106
macromolecule localization GO:0033036 771 0.104
cell projection organization GO:0030030 231 0.103
Fly
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.102
Fly
organelle fission GO:0048285 363 0.101
growth GO:0040007 562 0.100
Fly
reproductive structure development GO:0048608 850 0.096
negative regulation of metabolic process GO:0009892 240 0.095
axon guidance GO:0007411 82 0.095
establishment of localization in cell GO:0051649 318 0.094
Fly
neuron differentiation GO:0030182 217 0.092
Fly
lipid localization GO:0010876 573 0.092
single organism signaling GO:0044700 401 0.092
multi organism reproductive behavior GO:0044705 387 0.085
Worm
cell motility GO:0048870 313 0.085
Fly
multicellular organismal reproductive behavior GO:0033057 384 0.083
Worm
regulation of multicellular organismal development GO:2000026 317 0.080
development of primary sexual characteristics GO:0045137 840 0.079
cellular component biogenesis GO:0044085 297 0.077
maintenance of location GO:0051235 580 0.077
axonogenesis GO:0007409 102 0.076
cellular component movement GO:0006928 388 0.075
Fly
developmental growth GO:0048589 412 0.075
Fly
lipid storage GO:0019915 565 0.075
collagen and cuticulin based cuticle development GO:0040002 99 0.075
generation of neurons GO:0048699 235 0.073
Fly
multi multicellular organism process GO:0044706 390 0.073
Worm
cytoskeleton organization GO:0007010 339 0.072
Fly
oocyte construction GO:0007308 2 0.072
reproductive system development GO:0061458 850 0.072
positive regulation of developmental growth GO:0048639 354 0.072
organ development GO:0048513 1102 0.071
Worm Fly
cell cycle GO:0007049 526 0.070
single organism localization GO:1902578 518 0.068
Fly
genitalia development GO:0048806 741 0.067
body morphogenesis GO:0010171 620 0.067
neuron projection guidance GO:0097485 82 0.066
anatomical structure formation involved in morphogenesis GO:0048646 250 0.066
Fly
gamete generation GO:0007276 461 0.065
Fly
germ cell development GO:0007281 351 0.065
Fly
cellular component assembly GO:0022607 293 0.064
regulation of macromolecule metabolic process GO:0060255 421 0.062
negative regulation of biological process GO:0048519 567 0.060
actin filament based process GO:0030029 191 0.058
Fly
taxis GO:0042330 128 0.057
signal transduction GO:0007165 317 0.057
neuron projection development GO:0031175 187 0.056
regulation of post embryonic development GO:0048580 260 0.056
cell projection assembly GO:0030031 35 0.054
cell projection morphogenesis GO:0048858 148 0.053
regulation of developmental growth GO:0048638 389 0.052
single organism transport GO:0044765 447 0.052
Fly
protein complex biogenesis GO:0070271 186 0.051
cell migration GO:0016477 306 0.050
Fly
developmental maturation GO:0021700 26 0.049
rna localization GO:0006403 3 0.048
regulation of signaling GO:0023051 172 0.048
death GO:0016265 547 0.046
negative regulation of cellular process GO:0048523 239 0.045
multi organism behavior GO:0051705 389 0.044
Worm
signaling GO:0023052 401 0.043
chemotaxis GO:0006935 120 0.043
multi organism reproductive process GO:0044703 867 0.043
Worm Fly
regulation of cell projection assembly GO:0060491 3 0.043
cell death GO:0008219 547 0.043
positive regulation of cell projection organization GO:0031346 4 0.043
protein modification process GO:0036211 207 0.043
female gamete generation GO:0007292 254 0.043
Fly
response to external stimulus GO:0009605 289 0.043
positive regulation of developmental process GO:0051094 408 0.042
sexual reproduction GO:0019953 546 0.042
Fly
protein complex subunit organization GO:0071822 280 0.042
small molecule metabolic process GO:0044281 186 0.041
organic substance catabolic process GO:1901575 294 0.041
oocyte axis specification GO:0007309 2 0.040
heterocycle catabolic process GO:0046700 119 0.040
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.040
neuron projection morphogenesis GO:0048812 114 0.040
apoptotic cell clearance GO:0043277 111 0.039
phagocytosis GO:0006909 115 0.037
mitotic cell cycle process GO:1903047 194 0.037
ras protein signal transduction GO:0007265 31 0.037
lipid biosynthetic process GO:0008610 28 0.036
regulation of localization GO:0032879 194 0.036
myosin filament assembly GO:0031034 138 0.035
oviposition GO:0018991 364 0.035
Worm
regulation of growth GO:0040008 409 0.035
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.035
intracellular signal transduction GO:0035556 96 0.035
molting cycle GO:0042303 281 0.035
apoptotic process GO:0006915 478 0.034
behavior GO:0007610 527 0.034
Worm
regulation of ras protein signal transduction GO:0046578 41 0.034
filopodium assembly GO:0046847 2 0.033
positive regulation of multicellular organismal process GO:0051240 417 0.033
regulation of metabolic process GO:0019222 478 0.033
glycosyl compound metabolic process GO:1901657 100 0.032
cellular nitrogen compound catabolic process GO:0044270 119 0.032
protein complex assembly GO:0006461 186 0.032
actin cytoskeleton organization GO:0030036 184 0.031
Fly
regulation of filopodium assembly GO:0051489 2 0.031
membrane invagination GO:0010324 98 0.031
neurogenesis GO:0022008 236 0.030
Fly
organonitrogen compound metabolic process GO:1901564 151 0.030
regulation of cellular metabolic process GO:0031323 305 0.030
cell division GO:0051301 262 0.029
oogenesis GO:0048477 229 0.029
Fly
positive regulation of growth GO:0045927 369 0.029
cuticle development GO:0042335 100 0.029
carbohydrate derivative catabolic process GO:1901136 82 0.029
regulation of anatomical structure size GO:0090066 46 0.028
Fly
cell development GO:0048468 696 0.028
Fly
cell morphogenesis involved in differentiation GO:0000904 112 0.028
Fly
embryonic morphogenesis GO:0048598 152 0.027
cellular localization GO:0051641 360 0.027
Fly
engulfment of apoptotic cell GO:0043652 94 0.027
negative regulation of signaling GO:0023057 61 0.027
oxoacid metabolic process GO:0043436 47 0.027
regulation of behavior GO:0050795 97 0.027
Worm
negative regulation of nematode larval development GO:0061064 208 0.026
organelle assembly GO:0070925 214 0.026
cell morphogenesis GO:0000902 163 0.026
Fly
regulation of signal transduction GO:0009966 135 0.026
carboxylic acid metabolic process GO:0019752 34 0.026
macromolecule catabolic process GO:0009057 202 0.026
phosphate containing compound metabolic process GO:0006796 232 0.025
membrane organization GO:0061024 135 0.025
chromosome segregation GO:0007059 180 0.025
negative regulation of developmental process GO:0051093 227 0.025
myosin filament organization GO:0031033 138 0.025
regulation of multi organism process GO:0043900 69 0.025
phagocytosis engulfment GO:0006911 98 0.025
regulation of reproductive process GO:2000241 66 0.024
regulation of multicellular organism growth GO:0040014 373 0.024
purine ribonucleoside metabolic process GO:0046128 92 0.024
cellular macromolecular complex assembly GO:0034622 184 0.024
regulation of cell projection organization GO:0031344 38 0.024
carbohydrate derivative metabolic process GO:1901135 141 0.024
pole plasm assembly GO:0007315 2 0.024
regulation of gene expression epigenetic GO:0040029 163 0.024
ribose phosphate metabolic process GO:0019693 99 0.024
tissue development GO:0009888 112 0.023
Fly
meiotic cell cycle GO:0051321 335 0.023
regulation of cell communication GO:0010646 176 0.023
cellular protein complex assembly GO:0043623 178 0.022
catabolic process GO:0009056 318 0.022
striated muscle cell development GO:0055002 157 0.022
gene silencing GO:0016458 143 0.022
negative regulation of multicellular organismal process GO:0051241 236 0.022
regulation of gene expression GO:0010468 366 0.022
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.022
negative regulation of macromolecule metabolic process GO:0010605 229 0.022
multicellular organism growth GO:0035264 385 0.022
regulation of vulval development GO:0040028 248 0.021
phosphorus metabolic process GO:0006793 232 0.021
ribonucleotide metabolic process GO:0009259 99 0.021
rna interference GO:0016246 137 0.021
epithelium development GO:0060429 68 0.021
Fly
nucleobase containing compound metabolic process GO:0006139 406 0.021
nucleoside catabolic process GO:0009164 78 0.021
purine ribonucleotide metabolic process GO:0009150 95 0.021
cellular component assembly involved in morphogenesis GO:0010927 183 0.021
muscle cell development GO:0055001 158 0.021
establishment or maintenance of cell polarity GO:0007163 63 0.020
positive regulation of neuron differentiation GO:0045666 4 0.020
regulation of organelle organization GO:0033043 164 0.020
Fly
macromolecular complex subunit organization GO:0043933 320 0.020
cell proliferation GO:0008283 116 0.020
nucleoside triphosphate metabolic process GO:0009141 87 0.020
meiotic nuclear division GO:0007126 300 0.020
actomyosin structure organization GO:0031032 154 0.020
negative regulation of response to stimulus GO:0048585 73 0.020
neuromuscular junction development GO:0007528 2 0.020
purine nucleoside triphosphate metabolic process GO:0009144 87 0.020
posttranscriptional gene silencing by rna GO:0035194 143 0.020
muscle structure development GO:0061061 191 0.020
Worm
regulation of cellular component movement GO:0051270 62 0.019
head development GO:0060322 1 0.019
purine nucleoside catabolic process GO:0006152 75 0.019
system process GO:0003008 136 0.019
Worm
regulation of muscle system process GO:0090257 20 0.019
Worm
regulation of synapse assembly GO:0051963 2 0.019
nucleobase containing small molecule metabolic process GO:0055086 115 0.018
organic cyclic compound catabolic process GO:1901361 119 0.018
regulation of cell development GO:0060284 49 0.018
posttranscriptional gene silencing GO:0016441 143 0.018
regulation of cell motility GO:2000145 57 0.018
regulation of cellular component organization GO:0051128 248 0.018
Fly
pattern specification process GO:0007389 59 0.017
Fly
establishment of organelle localization GO:0051656 123 0.017
Fly
skeletal muscle organ development GO:0060538 3 0.017
actin cytoskeleton reorganization GO:0031532 4 0.017
nucleoside metabolic process GO:0009116 99 0.017
digestive system development GO:0055123 122 0.017
Fly
striated muscle myosin thick filament assembly GO:0071688 138 0.017
regulation of cell proliferation GO:0042127 105 0.017
positive regulation of multicellular organism growth GO:0040018 352 0.017
regulation of intracellular signal transduction GO:1902531 77 0.017
vulval development GO:0040025 333 0.017
glycosyl compound catabolic process GO:1901658 79 0.017
organelle localization GO:0051640 127 0.017
Fly
purine nucleoside triphosphate catabolic process GO:0009146 72 0.016
regulation of nematode larval development GO:0061062 260 0.016
spindle organization GO:0007051 92 0.016
cell maturation GO:0048469 26 0.016
purine ribonucleotide catabolic process GO:0009154 75 0.016
secretion by cell GO:0032940 138 0.016
negative regulation of signal transduction GO:0009968 60 0.016
posttranscriptional regulation of gene expression GO:0010608 166 0.016
ribonucleoside catabolic process GO:0042454 77 0.015
negative regulation of vulval development GO:0040027 206 0.015
regulation of cell differentiation GO:0045595 81 0.015
regulation of catalytic activity GO:0050790 78 0.015
regulation of cellular component size GO:0032535 40 0.015
gene silencing by rna GO:0031047 143 0.015
cellular catabolic process GO:0044248 199 0.015
lamellipodium organization GO:0097581 2 0.015
positive regulation of neuron projection development GO:0010976 4 0.015
muscle contraction GO:0006936 43 0.015
Worm
purine nucleotide catabolic process GO:0006195 75 0.015
muscle cell differentiation GO:0042692 171 0.015
regulation of mitotic cell cycle GO:0007346 76 0.015
cellular macromolecule localization GO:0070727 75 0.014
small molecule biosynthetic process GO:0044283 38 0.014
organic acid metabolic process GO:0006082 47 0.014
organic substance transport GO:0071702 113 0.014
macromolecular complex assembly GO:0065003 193 0.014
sphingolipid biosynthetic process GO:0030148 2 0.014
organophosphate catabolic process GO:0046434 81 0.014
regulation of meiotic cell cycle GO:0051445 136 0.014
neuron recognition GO:0008038 83 0.014
organophosphate metabolic process GO:0019637 125 0.013
ribonucleoside triphosphate catabolic process GO:0009203 72 0.013
intracellular transport GO:0046907 77 0.013
Fly
response to other organism GO:0051707 101 0.013
male anatomical structure morphogenesis GO:0090598 78 0.013
myofibril assembly GO:0030239 154 0.013
oocyte development GO:0048599 44 0.013
mitotic nuclear division GO:0007067 89 0.013
secretion GO:0046903 147 0.013
negative regulation of ion transmembrane transporter activity GO:0032413 3 0.013
nucleoside phosphate metabolic process GO:0006753 108 0.013
biosynthetic process GO:0009058 323 0.013
regulation of actin filament based process GO:0032970 22 0.013
Fly
digestive tract development GO:0048565 122 0.013
Fly
protein catabolic process GO:0030163 162 0.013
synaptic growth at neuromuscular junction GO:0051124 1 0.013
defense response GO:0006952 296 0.013
purine containing compound catabolic process GO:0072523 75 0.013
nucleotide catabolic process GO:0009166 77 0.012
negative regulation of gene expression GO:0010629 217 0.012
regulation of cellular amine metabolic process GO:0033238 0 0.012
regulation of muscle contraction GO:0006937 20 0.012
Worm
nucleotide metabolic process GO:0009117 108 0.012
regeneration GO:0031099 4 0.012
regulation of oviposition GO:0046662 43 0.012
negative regulation of cell communication GO:0010648 61 0.012
response to wounding GO:0009611 4 0.012
Human Fly
lipid metabolic process GO:0006629 77 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.012
gtp catabolic process GO:0006184 46 0.012
mitotic spindle organization GO:0007052 81 0.012
protein metabolic process GO:0019538 422 0.012
cell cycle switching mitotic to meiotic cell cycle GO:0051728 35 0.012
axis specification GO:0009798 23 0.012
cell type specific apoptotic process GO:0097285 4 0.012
regulation of system process GO:0044057 27 0.012
Worm
striated muscle cell differentiation GO:0051146 158 0.012
g1 s transition of mitotic cell cycle GO:0000082 2 0.012
small gtpase mediated signal transduction GO:0007264 32 0.011
cell growth GO:0016049 44 0.011
Fly
axonal fasciculation GO:0007413 79 0.011
golgi vesicle transport GO:0048193 3 0.011
aromatic compound catabolic process GO:0019439 116 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.011
hermaphrodite genitalia development GO:0040035 734 0.011
regulation of molecular function GO:0065009 89 0.011
ribonucleoside triphosphate metabolic process GO:0009199 87 0.011
ribosome biogenesis GO:0042254 4 0.011
single organism biosynthetic process GO:0044711 91 0.011
inductive cell migration GO:0040039 145 0.011
ribonucleotide catabolic process GO:0009261 75 0.011
cellular lipid metabolic process GO:0044255 40 0.011
protein oligomerization GO:0051259 4 0.011
modification dependent macromolecule catabolic process GO:0043632 32 0.011
post embryonic organ development GO:0048569 336 0.011
Fly
regulation of neuron differentiation GO:0045664 40 0.011
regulation of cell cycle GO:0051726 194 0.011
regulation of transport GO:0051049 91 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.011
developmental cell growth GO:0048588 39 0.011
cellular amine metabolic process GO:0044106 15 0.011
regulation of apoptotic signaling pathway GO:2001233 1 0.011
tube development GO:0035295 126 0.011
Fly
oocyte differentiation GO:0009994 45 0.010
purine nucleoside metabolic process GO:0042278 92 0.010
response to acid chemical GO:0001101 4 0.010
muscle organ morphogenesis GO:0048644 4 0.010

mlc-4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018
immune system disease DOID:2914 0 0.012
nervous system disease DOID:863 0 0.010