Caenorhabditis elegans

7 known processes

sir-2.2 (CELE_F46G10.7)

Protein SIR-2.2

sir-2.2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.200
gonad development GO:0008406 840 0.180
development of primary sexual characteristics GO:0045137 840 0.175
locomotion GO:0040011 1634 0.143
Worm
sex differentiation GO:0007548 909 0.130
reproductive system development GO:0061458 850 0.118
gamete generation GO:0007276 461 0.109
endocytosis GO:0006897 819 0.101
transport GO:0006810 1093 0.101
Mouse
single organism reproductive process GO:0044702 1196 0.096
regulation of developmental process GO:0050793 684 0.095
reproductive structure development GO:0048608 850 0.094
embryo development ending in birth or egg hatching GO:0009792 2992 0.090
vulval development GO:0040025 333 0.090
developmental process involved in reproduction GO:0003006 1165 0.089
regulation of biological quality GO:0065008 741 0.075
Mouse
multicellular organism reproduction GO:0032504 819 0.068
lipid storage GO:0019915 565 0.066
localization of cell GO:0051674 313 0.066
lipid localization GO:0010876 573 0.065
regulation of multicellular organismal process GO:0051239 726 0.063
aging GO:0007568 812 0.063
maintenance of location GO:0051235 580 0.061
single organism localization GO:1902578 518 0.060
Mouse
multi organism reproductive process GO:0044703 867 0.058
multicellular organismal aging GO:0010259 812 0.055
macromolecule localization GO:0033036 771 0.054
negative regulation of biological process GO:0048519 567 0.052
Mouse
post embryonic development GO:0009791 2152 0.052
programmed cell death GO:0012501 500 0.051
death GO:0016265 547 0.051
cell motility GO:0048870 313 0.051
developmental growth GO:0048589 412 0.050
organ development GO:0048513 1102 0.049
hermaphrodite genitalia development GO:0040035 734 0.048
establishment of localization GO:0051234 1171 0.047
Mouse
determination of adult lifespan GO:0008340 812 0.046
cellular component movement GO:0006928 388 0.044
cell migration GO:0016477 306 0.041
vesicle mediated transport GO:0016192 852 0.040
apoptotic process GO:0006915 478 0.039
positive regulation of epithelial cell proliferation GO:0050679 1 0.037
positive regulation of developmental growth GO:0048639 354 0.037
catabolic process GO:0009056 318 0.036
receptor mediated endocytosis GO:0006898 715 0.036
cell death GO:0008219 547 0.035
regulation of anatomical structure morphogenesis GO:0022603 51 0.035
post embryonic organ development GO:0048569 336 0.034
behavior GO:0007610 527 0.034
growth GO:0040007 562 0.033
sensory perception of bitter taste GO:0050913 3 0.033
positive regulation of multicellular organismal process GO:0051240 417 0.033
reproductive behavior GO:0019098 387 0.032
cell division GO:0051301 262 0.032
regulation of multi organism process GO:0043900 69 0.031
response to chemical GO:0042221 356 0.031
genitalia development GO:0048806 741 0.031
regulation of multicellular organismal development GO:2000026 317 0.029
negative regulation of multicellular organismal process GO:0051241 236 0.028
cellular nitrogen compound catabolic process GO:0044270 119 0.028
multicellular organism growth GO:0035264 385 0.027
germ cell development GO:0007281 351 0.026
organic substance catabolic process GO:1901575 294 0.026
macromolecule catabolic process GO:0009057 202 0.026
multicellular organismal reproductive process GO:0048609 815 0.026
regulation of signaling GO:0023051 172 0.026
Mouse
multi multicellular organism process GO:0044706 390 0.026
regulation of behavior GO:0050795 97 0.026
regulation of multicellular organism growth GO:0040014 373 0.025
cell surface receptor signaling pathway GO:0007166 149 0.025
body morphogenesis GO:0010171 620 0.025
negative regulation of nematode larval development GO:0061064 208 0.025
response to external stimulus GO:0009605 289 0.024
regulation of developmental growth GO:0048638 389 0.024
positive regulation of developmental process GO:0051094 408 0.023
regulation of nematode larval development GO:0061062 260 0.023
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.023
positive regulation of multicellular organism growth GO:0040018 352 0.022
neuron recognition GO:0008038 83 0.022
negative regulation of developmental process GO:0051093 227 0.022
regulation of metabolic process GO:0019222 478 0.022
Mouse
single organism transport GO:0044765 447 0.022
Mouse
cell cycle GO:0007049 526 0.022
oogenesis GO:0048477 229 0.022
multi organism behavior GO:0051705 389 0.022
nucleobase containing compound metabolic process GO:0006139 406 0.022
response to abiotic stimulus GO:0009628 152 0.021
negative regulation of vulval development GO:0040027 206 0.021
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.021
organelle localization GO:0051640 127 0.021
regulation of cell communication GO:0010646 176 0.021
Mouse
head development GO:0060322 1 0.020
response to wounding GO:0009611 4 0.020
cell fate commitment GO:0045165 139 0.019
anatomical structure formation involved in morphogenesis GO:0048646 250 0.019
multicellular organismal reproductive behavior GO:0033057 384 0.019
regulation of reproductive process GO:2000241 66 0.019
heterocycle catabolic process GO:0046700 119 0.018
cell development GO:0048468 696 0.018
oviposition GO:0018991 364 0.018
neuromuscular junction development GO:0007528 2 0.017
regulation of oviposition GO:0046662 43 0.017
positive regulation of growth GO:0045927 369 0.017
positive regulation of neurotransmitter transport GO:0051590 11 0.016
regulation of post embryonic development GO:0048580 260 0.016
phosphate containing compound metabolic process GO:0006796 232 0.016
nucleic acid metabolic process GO:0090304 299 0.016
regulation of growth GO:0040008 409 0.015
protein catabolic process GO:0030163 162 0.015
regulation of locomotion GO:0040012 161 0.015
gene expression GO:0010467 412 0.015
system process GO:0003008 136 0.015
ras protein signal transduction GO:0007265 31 0.015
positive regulation of cellular metabolic process GO:0031325 178 0.014
defense response GO:0006952 296 0.014
posttranscriptional gene silencing GO:0016441 143 0.014
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.014
neuron projection development GO:0031175 187 0.014
cell type specific apoptotic process GO:0097285 4 0.014
establishment of organelle localization GO:0051656 123 0.014
regulation of cellular component movement GO:0051270 62 0.014
positive regulation of cellular process GO:0048522 332 0.014
cell morphogenesis GO:0000902 163 0.014
regulation of feeding behavior GO:0060259 38 0.014
microtubule based process GO:0007017 182 0.013
regulation of localization GO:0032879 194 0.013
Mouse
nucleoside metabolic process GO:0009116 99 0.013
rna interference GO:0016246 137 0.013
regulation of g protein coupled receptor protein signaling pathway GO:0008277 4 0.013
positive regulation of metabolic process GO:0009893 187 0.013
Mouse
cellular response to topologically incorrect protein GO:0035967 76 0.013
signal transduction GO:0007165 317 0.013
cellular catabolic process GO:0044248 199 0.013
organic cyclic compound catabolic process GO:1901361 119 0.013
sexual reproduction GO:0019953 546 0.013
regulation of vulval development GO:0040028 248 0.013
negative regulation of post embryonic development GO:0048581 208 0.013
cellular macromolecule catabolic process GO:0044265 73 0.013
nucleoside phosphate catabolic process GO:1901292 77 0.012
negative regulation of cellular process GO:0048523 239 0.012
Mouse
response to mechanical stimulus GO:0009612 28 0.012
regulation of cell division GO:0051302 142 0.012
small molecule metabolic process GO:0044281 186 0.012
Mouse
posttranscriptional gene silencing by rna GO:0035194 143 0.012
secretion by cell GO:0032940 138 0.012
Mouse
regulation of cellular component organization GO:0051128 248 0.012
molting cycle GO:0042303 281 0.012
establishment of localization in cell GO:0051649 318 0.012
Mouse
muscle structure development GO:0061061 191 0.012
cell recognition GO:0008037 85 0.012
defense response to bacterium GO:0042742 86 0.012
regulation of apoptotic signaling pathway GO:2001233 1 0.012
embryonic morphogenesis GO:0048598 152 0.011
positive regulation of signaling GO:0023056 66 0.011
synaptic growth at neuromuscular junction GO:0051124 1 0.011
negative regulation of gene expression GO:0010629 217 0.011
pigmentation GO:0043473 2 0.011
memory GO:0007613 3 0.011
regulation of epithelial cell proliferation GO:0050678 1 0.011
cellular protein complex assembly GO:0043623 178 0.011
intracellular signal transduction GO:0035556 96 0.011
nucleotide catabolic process GO:0009166 77 0.011
cell cycle process GO:0022402 482 0.011
ribonucleotide catabolic process GO:0009261 75 0.011
signaling GO:0023052 401 0.011
Mouse
positive regulation of cell communication GO:0010647 69 0.011
ribonucleoside catabolic process GO:0042454 77 0.011
nucleobase containing compound catabolic process GO:0034655 114 0.011
organelle organization GO:0006996 783 0.011
negative regulation of macromolecule metabolic process GO:0010605 229 0.010
regulation of macromolecule metabolic process GO:0060255 421 0.010
nucleobase containing small molecule metabolic process GO:0055086 115 0.010
sensory organ morphogenesis GO:0090596 2 0.010
response to biotic stimulus GO:0009607 101 0.010
aromatic compound catabolic process GO:0019439 116 0.010
response to other organism GO:0051707 101 0.010
organic substance transport GO:0071702 113 0.010
Mouse
cation transport GO:0006812 78 0.010
tissue development GO:0009888 112 0.010
regulation of response to stimulus GO:0048583 243 0.010
nematode male tail tip morphogenesis GO:0045138 77 0.010
gene silencing by rna GO:0031047 143 0.010

sir-2.2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.011
disease of anatomical entity DOID:7 0 0.011
bone marrow disease DOID:4961 0 0.011
hematopoietic system disease DOID:74 0 0.011