Caenorhabditis elegans

8 known processes

nhl-2 (CELE_F26F4.7)

Protein NHL-2

nhl-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.489
embryo development GO:0009790 3052 0.483
developmental process involved in reproduction GO:0003006 1165 0.424
Worm
post embryonic development GO:0009791 2152 0.405
Worm
establishment of localization GO:0051234 1171 0.389
Worm
multicellular organism reproduction GO:0032504 819 0.385
Worm
locomotion GO:0040011 1634 0.353
Worm
organelle organization GO:0006996 783 0.321
germ cell development GO:0007281 351 0.317
sexual reproduction GO:0019953 546 0.311
Worm
growth GO:0040007 562 0.310
Worm
body morphogenesis GO:0010171 620 0.308
Worm
female gamete generation GO:0007292 254 0.265
aging GO:0007568 812 0.264
reproductive system development GO:0061458 850 0.255
endocytosis GO:0006897 819 0.244
Worm
vesicle mediated transport GO:0016192 852 0.243
Worm
multicellular organismal aging GO:0010259 812 0.226
fertilization GO:0009566 63 0.223
transport GO:0006810 1093 0.215
Worm
oogenesis GO:0048477 229 0.214
cell development GO:0048468 696 0.210
cell surface receptor signaling pathway GO:0007166 149 0.207
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.204
multi organism reproductive process GO:0044703 867 0.199
Worm
regulation of growth GO:0040008 409 0.197
Worm
single organism localization GO:1902578 518 0.184
sex differentiation GO:0007548 909 0.179
Worm
single organism transport GO:0044765 447 0.176
organelle fission GO:0048285 363 0.176
development of primary sexual characteristics GO:0045137 840 0.173
regulation of developmental growth GO:0048638 389 0.169
Worm
reproductive structure development GO:0048608 850 0.168
single organism organelle organization GO:1902589 501 0.167
gonad development GO:0008406 840 0.165
meiotic nuclear division GO:0007126 300 0.163
receptor mediated endocytosis GO:0006898 715 0.162
Worm
determination of adult lifespan GO:0008340 812 0.158
multicellular organismal reproductive process GO:0048609 815 0.157
Worm
single fertilization GO:0007338 61 0.155
regulation of vulval development GO:0040028 248 0.154
Worm
programmed cell death GO:0012501 500 0.152
Worm
cell death GO:0008219 547 0.145
Worm
regulation of meiotic cell cycle GO:0051445 136 0.144
developmental growth GO:0048589 412 0.142
Worm
positive regulation of developmental growth GO:0048639 354 0.135
Worm
protein metabolic process GO:0019538 422 0.135
Worm
single organism reproductive process GO:0044702 1196 0.134
Worm
neuron projection guidance GO:0097485 82 0.133
multicellular organism growth GO:0035264 385 0.133
Worm
regulation of developmental process GO:0050793 684 0.132
regulation of multicellular organismal process GO:0051239 726 0.132
Worm
gamete generation GO:0007276 461 0.128
Worm
cell cycle process GO:0022402 482 0.124
regulation of cell communication GO:0010646 176 0.121
macromolecule modification GO:0043412 218 0.121
Worm
response to chemical GO:0042221 356 0.119
organ development GO:0048513 1102 0.113
Worm
regulation of signal transduction GO:0009966 135 0.112
single organism signaling GO:0044700 401 0.111
macromolecule localization GO:0033036 771 0.107
meiotic cell cycle GO:0051321 335 0.107
positive regulation of multicellular organismal process GO:0051240 417 0.106
Worm
regulation of response to stimulus GO:0048583 243 0.104
gene expression GO:0010467 412 0.099
Worm
chemotaxis GO:0006935 120 0.097
death GO:0016265 547 0.095
Worm
meiotic chromosome segregation GO:0045132 139 0.095
cellular protein modification process GO:0006464 207 0.094
Worm
axon guidance GO:0007411 82 0.094
nucleic acid metabolic process GO:0090304 299 0.093
cellular protein metabolic process GO:0044267 279 0.092
Worm
genitalia development GO:0048806 741 0.089
regulation of biological quality GO:0065008 741 0.082
regulation of nuclear division GO:0051783 115 0.082
regulation of multicellular organism growth GO:0040014 373 0.082
Worm
nucleobase containing compound metabolic process GO:0006139 406 0.081
taxis GO:0042330 128 0.081
pronuclear migration GO:0035046 51 0.080
regulation of macromolecule metabolic process GO:0060255 421 0.080
Worm
positive regulation of growth GO:0045927 369 0.079
Worm
signal transduction GO:0007165 317 0.078
protein catabolic process GO:0030163 162 0.077
regulation of biosynthetic process GO:0009889 189 0.076
apoptotic process GO:0006915 478 0.076
Worm
maintenance of location GO:0051235 580 0.075
cell cycle GO:0007049 526 0.074
embryonic morphogenesis GO:0048598 152 0.068
protein modification process GO:0036211 207 0.068
Worm
multicellular organismal reproductive behavior GO:0033057 384 0.068
negative regulation of vulval development GO:0040027 206 0.066
Worm
lipid localization GO:0010876 573 0.066
regulation of post embryonic development GO:0048580 260 0.066
Worm
regulation of cell cycle process GO:0010564 145 0.066
mitotic cell cycle process GO:1903047 194 0.065
cellular component biogenesis GO:0044085 297 0.065
Worm
small molecule metabolic process GO:0044281 186 0.065
cell division GO:0051301 262 0.064
positive regulation of developmental process GO:0051094 408 0.063
Worm
epithelium development GO:0060429 68 0.062
Worm
regulation of signaling GO:0023051 172 0.061
lipid storage GO:0019915 565 0.061
regulation of organelle organization GO:0033043 164 0.061
cellular localization GO:0051641 360 0.061
posttranscriptional gene silencing GO:0016441 143 0.060
Worm
regulation of meiosis GO:0040020 94 0.060
negative regulation of biological process GO:0048519 567 0.060
Worm
regulation of metabolic process GO:0019222 478 0.059
Worm
multi organism behavior GO:0051705 389 0.059
oocyte differentiation GO:0009994 45 0.058
macromolecule biosynthetic process GO:0009059 250 0.057
meiotic cell cycle process GO:1903046 170 0.057
organic substance catabolic process GO:1901575 294 0.056
regulation of cell division GO:0051302 142 0.056
cellular component assembly GO:0022607 293 0.056
phosphorus metabolic process GO:0006793 232 0.056
negative regulation of macromolecule metabolic process GO:0010605 229 0.056
Worm
signaling GO:0023052 401 0.056
organic substance biosynthetic process GO:1901576 323 0.055
embryonic body morphogenesis GO:0010172 49 0.053
biosynthetic process GO:0009058 323 0.053
behavior GO:0007610 527 0.053
cellular biosynthetic process GO:0044249 315 0.052
regulation of cell cycle GO:0051726 194 0.051
cytoskeleton organization GO:0007010 339 0.051
cell motility GO:0048870 313 0.050
cell proliferation GO:0008283 116 0.050
vulval development GO:0040025 333 0.050
Worm
cell fate commitment GO:0045165 139 0.049
Worm
gene silencing GO:0016458 143 0.049
Worm
cellular component movement GO:0006928 388 0.049
response to organic substance GO:0010033 131 0.049
establishment of localization in cell GO:0051649 318 0.049
regulation of multicellular organismal development GO:2000026 317 0.048
Worm
microtubule based process GO:0007017 182 0.048
response to external stimulus GO:0009605 289 0.048
phosphorylation GO:0016310 116 0.048
cell migration GO:0016477 306 0.048
negative regulation of multicellular organismal process GO:0051241 236 0.047
Worm
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.047
Worm
macromolecular complex subunit organization GO:0043933 320 0.046
positive regulation of multicellular organism growth GO:0040018 352 0.046
Worm
regulation of cellular component organization GO:0051128 248 0.046
negative regulation of nematode larval development GO:0061064 208 0.046
Worm
negative regulation of gene expression GO:0010629 217 0.044
Worm
nervous system development GO:0007399 253 0.044
phagocytosis GO:0006909 115 0.044
establishment of spindle localization GO:0051293 51 0.043
head development GO:0060322 1 0.043
p38mapk cascade GO:0038066 2 0.042
ribosome biogenesis GO:0042254 4 0.042
Worm
regulation of gene expression epigenetic GO:0040029 163 0.042
Worm
regulation of gene expression GO:0010468 366 0.041
Worm
oocyte development GO:0048599 44 0.041
protein phosphorylation GO:0006468 85 0.041
multi organism reproductive behavior GO:0044705 387 0.041
regulation of nematode larval development GO:0061062 260 0.041
Worm
tissue development GO:0009888 112 0.040
Worm
positive regulation of cellular metabolic process GO:0031325 178 0.040
regulation of translation GO:0006417 19 0.039
protein complex subunit organization GO:0071822 280 0.039
single organism behavior GO:0044708 83 0.038
regulation of nitrogen compound metabolic process GO:0051171 222 0.038
protein localization GO:0008104 205 0.038
molting cycle GO:0042303 281 0.038
Worm
mitotic nuclear division GO:0007067 89 0.038
axonogenesis GO:0007409 102 0.038
chromosome organization GO:0051276 104 0.037
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.036
organelle assembly GO:0070925 214 0.036
negative regulation of developmental process GO:0051093 227 0.036
Worm
positive regulation of cellular process GO:0048522 332 0.036
mitotic spindle organization GO:0007052 81 0.035
establishment of mitotic spindle localization GO:0040001 41 0.035
posttranscriptional gene silencing by rna GO:0035194 143 0.035
Worm
posttranscriptional regulation of gene expression GO:0010608 166 0.035
Worm
rna metabolic process GO:0016070 228 0.035
macromolecule catabolic process GO:0009057 202 0.035
post embryonic organ development GO:0048569 336 0.035
Worm
negative regulation of metabolic process GO:0009892 240 0.034
Worm
regulation of localization GO:0032879 194 0.034
neurogenesis GO:0022008 236 0.034
nucleobase containing compound biosynthetic process GO:0034654 184 0.034
single organism cellular localization GO:1902580 72 0.033
axon development GO:0061564 163 0.033
male sex differentiation GO:0046661 86 0.033
Worm
regulation of cell morphogenesis GO:0022604 40 0.033
oviposition GO:0018991 364 0.032
multi multicellular organism process GO:0044706 390 0.032
protein complex assembly GO:0006461 186 0.032
carbohydrate derivative metabolic process GO:1901135 141 0.032
regulation of cellular localization GO:0060341 42 0.031
digestive tract morphogenesis GO:0048546 76 0.031
catabolic process GO:0009056 318 0.031
establishment of organelle localization GO:0051656 123 0.031
phosphate containing compound metabolic process GO:0006796 232 0.031
heterocycle biosynthetic process GO:0018130 187 0.030
purine nucleotide metabolic process GO:0006163 95 0.030
developmental growth involved in morphogenesis GO:0060560 37 0.030
hermaphrodite genitalia development GO:0040035 734 0.030
localization of cell GO:0051674 313 0.029
positive regulation of cell communication GO:0010647 69 0.029
inductive cell migration GO:0040039 145 0.029
regulation of protein metabolic process GO:0051246 81 0.029
translation GO:0006412 37 0.029
regulation of primary metabolic process GO:0080090 292 0.028
regulation of cellular metabolic process GO:0031323 305 0.028
cell growth GO:0016049 44 0.028
nuclear migration GO:0007097 54 0.028
cleavage involved in rrna processing GO:0000469 2 0.027
response to wounding GO:0009611 4 0.027
positive regulation of metabolic process GO:0009893 187 0.027
organelle localization GO:0051640 127 0.027
regulation of cytoplasmic transport GO:1903649 3 0.027
spindle localization GO:0051653 51 0.027
golgi vesicle transport GO:0048193 3 0.026
cellular component morphogenesis GO:0032989 318 0.026
mrna metabolic process GO:0016071 31 0.026
regulation of cell proliferation GO:0042127 105 0.026
tube morphogenesis GO:0035239 79 0.026
secretion GO:0046903 147 0.025
membrane organization GO:0061024 135 0.025
chromosome segregation GO:0007059 180 0.025
apoptotic cell clearance GO:0043277 111 0.025
reproductive behavior GO:0019098 387 0.025
regulation of mitosis GO:0007088 18 0.025
gene silencing by rna GO:0031047 143 0.025
Worm
cell part morphogenesis GO:0032990 152 0.025
nucleic acid templated transcription GO:0097659 169 0.024
response to abiotic stimulus GO:0009628 152 0.024
oocyte construction GO:0007308 2 0.024
establishment of cell polarity GO:0030010 46 0.024
establishment of spindle orientation GO:0051294 34 0.024
negative regulation of response to stimulus GO:0048585 73 0.024
negative regulation of signal transduction GO:0009968 60 0.023
nucleus organization GO:0006997 38 0.023
regulation of nucleocytoplasmic transport GO:0046822 3 0.023
establishment of nucleus localization GO:0040023 55 0.022
cellular catabolic process GO:0044248 199 0.022
negative regulation of post embryonic development GO:0048581 208 0.022
Worm
rna interference GO:0016246 137 0.022
Worm
regulation of mitotic cell cycle GO:0007346 76 0.022
single organism biosynthetic process GO:0044711 91 0.022
protein complex biogenesis GO:0070271 186 0.022
regulation of cellular biosynthetic process GO:0031326 189 0.022
oocyte axis specification GO:0007309 2 0.022
negative regulation of translation GO:0017148 10 0.022
cell morphogenesis GO:0000902 163 0.021
phagocytosis engulfment GO:0006911 98 0.021
neurological system process GO:0050877 53 0.021
protein localization to mitochondrion GO:0070585 2 0.021
chromatin organization GO:0006325 32 0.021
cell projection organization GO:0030030 231 0.021
organic acid metabolic process GO:0006082 47 0.021
cellular protein complex assembly GO:0043623 178 0.021
regulation of macromolecule biosynthetic process GO:0010556 189 0.021
cellular macromolecule biosynthetic process GO:0034645 247 0.021
cellular protein localization GO:0034613 75 0.021
negative regulation of cell communication GO:0010648 61 0.020
regulation of multi organism process GO:0043900 69 0.020
negative regulation of neurogenesis GO:0050768 4 0.020
neuron recognition GO:0008038 83 0.020
spindle organization GO:0007051 92 0.020
regulation of nucleic acid templated transcription GO:1903506 165 0.020
macromolecular complex assembly GO:0065003 193 0.020
organic substance transport GO:0071702 113 0.020
cell recognition GO:0008037 85 0.020
negative regulation of cellular process GO:0048523 239 0.020
Worm
positive regulation of signaling GO:0023056 66 0.020
nuclear pore organization GO:0006999 2 0.020
chemosensory behavior GO:0007635 33 0.019
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.019
actin filament based process GO:0030029 191 0.019
axon extension GO:0048675 37 0.019
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000466 1 0.019
intracellular transport GO:0046907 77 0.019
positive regulation of neurogenesis GO:0050769 4 0.018
rna biosynthetic process GO:0032774 169 0.018
small gtpase mediated signal transduction GO:0007264 32 0.018
negative regulation of cellular metabolic process GO:0031324 95 0.018
heterocycle catabolic process GO:0046700 119 0.018
negative regulation of signaling GO:0023057 61 0.018
muscle structure development GO:0061061 191 0.018
organonitrogen compound metabolic process GO:1901564 151 0.018
regulation of cell differentiation GO:0045595 81 0.018
Worm
secretion by cell GO:0032940 138 0.018
positive regulation of signal transduction GO:0009967 40 0.018
defense response GO:0006952 296 0.017
muscle cell differentiation GO:0042692 171 0.017
cellular component assembly involved in morphogenesis GO:0010927 183 0.017
establishment of mitotic spindle orientation GO:0000132 28 0.017
negative regulation of gene expression epigenetic GO:0045814 2 0.017
regulation of intracellular signal transduction GO:1902531 77 0.017
oxoacid metabolic process GO:0043436 47 0.017
developmental cell growth GO:0048588 39 0.017
actin cytoskeleton organization GO:0030036 184 0.017
cellular response to organic substance GO:0071310 119 0.017
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.017
canonical wnt signaling pathway GO:0060070 3 0.017
neuron projection morphogenesis GO:0048812 114 0.017
cellular response to chemical stimulus GO:0070887 129 0.017
single organism intracellular transport GO:1902582 70 0.016
positive regulation of gene expression GO:0010628 112 0.016
positive regulation of intracellular transport GO:0032388 2 0.016
female meiotic division GO:0007143 17 0.016
engulfment of apoptotic cell GO:0043652 94 0.016
response to external biotic stimulus GO:0043207 101 0.016
myosin filament assembly GO:0031034 138 0.016
asymmetric protein localization GO:0008105 35 0.016
protein targeting to mitochondrion GO:0006626 2 0.016
rrna metabolic process GO:0016072 3 0.016
rna processing GO:0006396 34 0.016
positive regulation of cellular protein catabolic process GO:1903364 3 0.015
wnt signaling pathway GO:0016055 27 0.015
regulation of bmp signaling pathway GO:0030510 3 0.015
regulation of cellular amine metabolic process GO:0033238 0 0.015
spermatogenesis GO:0007283 41 0.015
neuron development GO:0048666 199 0.015
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.015
collagen and cuticulin based cuticle development GO:0040002 99 0.015
regulation of protein localization GO:0032880 50 0.015
tissue morphogenesis GO:0048729 65 0.015
digestive tract development GO:0048565 122 0.015
positive regulation of rna metabolic process GO:0051254 103 0.015
cellular macromolecule localization GO:0070727 75 0.015
regulation of cellular ketone metabolic process GO:0010565 3 0.015
positive regulation of cellular catabolic process GO:0031331 35 0.015
ovulation GO:0030728 33 0.015
cellular nitrogen compound catabolic process GO:0044270 119 0.015
organophosphate metabolic process GO:0019637 125 0.015
membrane invagination GO:0010324 98 0.014
rna polyadenylation GO:0043631 3 0.014
anatomical structure formation involved in morphogenesis GO:0048646 250 0.014
purine nucleoside triphosphate metabolic process GO:0009144 87 0.014
regulation of behavior GO:0050795 97 0.014
regulation of ras protein signal transduction GO:0046578 41 0.014
male anatomical structure morphogenesis GO:0090598 78 0.014
Worm
regulation of cellular protein metabolic process GO:0032268 75 0.014
response to mechanical stimulus GO:0009612 28 0.014
regulation of axonogenesis GO:0050770 24 0.014
cell cell signaling GO:0007267 118 0.014
transcription from rna polymerase ii promoter GO:0006366 149 0.014
adult locomotory behavior GO:0008344 1 0.014
purine ribonucleotide metabolic process GO:0009150 95 0.014
cellular response to abiotic stimulus GO:0071214 4 0.014
male gamete generation GO:0048232 41 0.014
nucleobase containing compound catabolic process GO:0034655 114 0.014
pattern specification process GO:0007389 59 0.013
neuron projection extension GO:1990138 37 0.013
meiosis i GO:0007127 19 0.013
chromatin modification GO:0016568 32 0.013
transmembrane transport GO:0055085 110 0.013
regulation of protein import into nucleus GO:0042306 3 0.013
nucleoside metabolic process GO:0009116 99 0.013
defense response to bacterium GO:0042742 86 0.013
glycosyl compound metabolic process GO:1901657 100 0.013
spindle assembly GO:0051225 8 0.013
organonitrogen compound catabolic process GO:1901565 90 0.013
positive regulation of cell cycle GO:0045787 55 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.013
positive regulation of response to stimulus GO:0048584 55 0.013
regeneration GO:0031099 4 0.013
regulation of cellular component size GO:0032535 40 0.013
detection of abiotic stimulus GO:0009582 4 0.013
carboxylic acid metabolic process GO:0019752 34 0.013
sensory organ morphogenesis GO:0090596 2 0.013
cellular macromolecule catabolic process GO:0044265 73 0.012
nematode male tail tip morphogenesis GO:0045138 77 0.012
Worm
mechanosensory behavior GO:0007638 25 0.012
regulation of phosphorus metabolic process GO:0051174 81 0.012
regulation of protein targeting GO:1903533 3 0.012
striated muscle myosin thick filament assembly GO:0071688 138 0.012
regulation of apoptotic signaling pathway GO:2001233 1 0.012
rna localization GO:0006403 3 0.012
generation of neurons GO:0048699 235 0.012
regulation of anatomical structure morphogenesis GO:0022603 51 0.012
regulation of transport GO:0051049 91 0.012
dna metabolic process GO:0006259 74 0.012
dauer larval development GO:0040024 92 0.012
cell volume homeostasis GO:0006884 1 0.012
guanosine containing compound metabolic process GO:1901068 49 0.012
aromatic compound catabolic process GO:0019439 116 0.012
ras protein signal transduction GO:0007265 31 0.012
cell projection morphogenesis GO:0048858 148 0.012
myosin filament organization GO:0031033 138 0.012
rna transport GO:0050658 3 0.012
pole plasm assembly GO:0007315 2 0.012
regulation of response to wounding GO:1903034 1 0.012
peptidyl amino acid modification GO:0018193 58 0.012
gastrulation GO:0007369 58 0.012
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.011
muscle cell development GO:0055001 158 0.011
purine ribonucleoside metabolic process GO:0046128 92 0.011
response to other organism GO:0051707 101 0.011
maintenance of protein location in cell GO:0032507 12 0.011
regulation of cellular catabolic process GO:0031329 51 0.011
epithelial tube morphogenesis GO:0060562 1 0.011
bmp signaling pathway GO:0030509 3 0.011
cell cycle switching mitotic to meiotic cell cycle GO:0051728 35 0.011
response to bacterium GO:0009617 86 0.011
positive regulation of catabolic process GO:0009896 38 0.011
striated muscle cell development GO:0055002 157 0.011
nucleobase containing small molecule metabolic process GO:0055086 115 0.011
defense response to other organism GO:0098542 100 0.011
negative regulation of cell morphogenesis involved in differentiation GO:0010771 2 0.011
translational initiation GO:0006413 2 0.011
regulation of catabolic process GO:0009894 57 0.011
carbohydrate biosynthetic process GO:0016051 4 0.011
cell type specific apoptotic process GO:0097285 4 0.011
positive regulation of meiotic cell cycle GO:0051446 47 0.011
organism emergence from protective structure GO:0071684 48 0.011
establishment of rna localization GO:0051236 3 0.011
muscle tissue development GO:0060537 1 0.011
establishment or maintenance of cell polarity GO:0007163 63 0.011
tube development GO:0035295 126 0.011
synaptic transmission GO:0007268 106 0.011
organonitrogen compound biosynthetic process GO:1901566 44 0.011
cellular amino acid metabolic process GO:0006520 15 0.011
g1 s transition of mitotic cell cycle GO:0000082 2 0.011
positive regulation of cellular biosynthetic process GO:0031328 109 0.011
positive regulation of macromolecule metabolic process GO:0010604 149 0.011
memory GO:0007613 3 0.011
cellular macromolecular complex assembly GO:0034622 184 0.011
nucleus localization GO:0051647 55 0.011
intracellular protein transmembrane import GO:0044743 3 0.010
innate immune response GO:0045087 190 0.010
regulation of molecular function GO:0065009 89 0.010
detection of external stimulus GO:0009581 4 0.010
positive regulation of nucleic acid templated transcription GO:1903508 102 0.010
positive regulation of biosynthetic process GO:0009891 109 0.010
internal peptidyl lysine acetylation GO:0018393 3 0.010
chromatin remodeling GO:0006338 2 0.010
cellular response to stress GO:0033554 162 0.010
positive regulation of protein transport GO:0051222 4 0.010
ribose phosphate metabolic process GO:0019693 99 0.010

nhl-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
progeria DOID:3911 0 0.017
disease of anatomical entity DOID:7 0 0.014
nervous system disease DOID:863 0 0.014