Caenorhabditis elegans

10 known processes

smc-6 (CELE_F54D5.14)

Protein SMC-6

smc-6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
meiotic nuclear division GO:0007126 300 0.766
embryo development GO:0009790 3052 0.741
meiotic cell cycle GO:0051321 335 0.622
nucleic acid metabolic process GO:0090304 299 0.466
Human
regulation of meiosis GO:0040020 94 0.406
nucleobase containing compound metabolic process GO:0006139 406 0.395
Human
rna biosynthetic process GO:0032774 169 0.354
embryo development ending in birth or egg hatching GO:0009792 2992 0.328
transport GO:0006810 1093 0.314
organic substance biosynthetic process GO:1901576 323 0.301
apoptotic process GO:0006915 478 0.274
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.265
regulation of metabolic process GO:0019222 478 0.264
cellular macromolecule biosynthetic process GO:0034645 247 0.250
regulation of primary metabolic process GO:0080090 292 0.246
regulation of cell cycle process GO:0010564 145 0.245
regulation of macromolecule metabolic process GO:0060255 421 0.240
regulation of nucleic acid templated transcription GO:1903506 165 0.231
cellular biosynthetic process GO:0044249 315 0.219
meiotic cell cycle process GO:1903046 170 0.211
regulation of transcription dna templated GO:0006355 164 0.194
regulation of meiotic cell cycle GO:0051445 136 0.192
biosynthetic process GO:0009058 323 0.188
organic cyclic compound biosynthetic process GO:1901362 195 0.182
regulation of nitrogen compound metabolic process GO:0051171 222 0.177
post embryonic development GO:0009791 2152 0.176
multi organism reproductive process GO:0044703 867 0.173
locomotion GO:0040011 1634 0.172
transcription dna templated GO:0006351 168 0.171
establishment of localization GO:0051234 1171 0.169
macromolecular complex subunit organization GO:0043933 320 0.147
chromosome organization involved in meiosis GO:0070192 25 0.145
dna metabolic process GO:0006259 74 0.139
Human
cell development GO:0048468 696 0.135
cellular nitrogen compound biosynthetic process GO:0044271 192 0.134
hermaphrodite genitalia development GO:0040035 734 0.131
cell cycle process GO:0022402 482 0.130
attachment of spindle microtubules to kinetochore GO:0008608 8 0.128
gene expression GO:0010467 412 0.127
genitalia development GO:0048806 741 0.120
meiotic chromosome segregation GO:0045132 139 0.115
reproductive structure development GO:0048608 850 0.114
multicellular organism reproduction GO:0032504 819 0.110
endocytosis GO:0006897 819 0.108
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.106
sex differentiation GO:0007548 909 0.105
cell motility GO:0048870 313 0.104
regulation of cell cycle GO:0051726 194 0.103
receptor mediated endocytosis GO:0006898 715 0.103
regulation of cellular metabolic process GO:0031323 305 0.102
regulation of gene expression GO:0010468 366 0.098
nucleobase containing compound biosynthetic process GO:0034654 184 0.097
macromolecule biosynthetic process GO:0009059 250 0.096
cell division GO:0051301 262 0.090
fertilization GO:0009566 63 0.089
macromolecular complex assembly GO:0065003 193 0.088
aromatic compound biosynthetic process GO:0019438 192 0.087
cell death GO:0008219 547 0.084
organelle organization GO:0006996 783 0.084
Human
death GO:0016265 547 0.081
regulation of cellular biosynthetic process GO:0031326 189 0.078
regulation of rna biosynthetic process GO:2001141 165 0.071
catabolic process GO:0009056 318 0.071
cellular protein complex assembly GO:0043623 178 0.070
cell cycle GO:0007049 526 0.069
development of primary sexual characteristics GO:0045137 840 0.068
programmed cell death GO:0012501 500 0.068
protein complex assembly GO:0006461 186 0.067
pronuclear migration GO:0035046 51 0.067
molting cycle GO:0042303 281 0.067
neuron projection development GO:0031175 187 0.066
gonad development GO:0008406 840 0.066
multicellular organismal reproductive process GO:0048609 815 0.064
determination of adult lifespan GO:0008340 812 0.064
regulation of rna metabolic process GO:0051252 173 0.064
regulation of nuclear division GO:0051783 115 0.063
organ development GO:0048513 1102 0.063
small molecule metabolic process GO:0044281 186 0.060
protein complex biogenesis GO:0070271 186 0.060
cell proliferation GO:0008283 116 0.060
cellular component movement GO:0006928 388 0.060
macromolecule localization GO:0033036 771 0.059
single fertilization GO:0007338 61 0.058
positive regulation of multicellular organismal process GO:0051240 417 0.058
gamete generation GO:0007276 461 0.057
multicellular organismal aging GO:0010259 812 0.057
neuron development GO:0048666 199 0.057
maintenance of location GO:0051235 580 0.057
signaling GO:0023052 401 0.056
cell migration GO:0016477 306 0.056
neuron projection morphogenesis GO:0048812 114 0.055
cellular response to stress GO:0033554 162 0.055
Human
positive regulation of metabolic process GO:0009893 187 0.054
regulation of cellular component organization GO:0051128 248 0.053
rna metabolic process GO:0016070 228 0.053
neuron differentiation GO:0030182 217 0.053
chromosome organization GO:0051276 104 0.052
Human
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.052
cell morphogenesis involved in differentiation GO:0000904 112 0.052
cellular component morphogenesis GO:0032989 318 0.051
cellular catabolic process GO:0044248 199 0.051
cellular component assembly GO:0022607 293 0.050
phosphorus metabolic process GO:0006793 232 0.050
organelle fission GO:0048285 363 0.049
developmental process involved in reproduction GO:0003006 1165 0.049
regulation of biological quality GO:0065008 741 0.049
Human
single organism organelle organization GO:1902589 501 0.048
Human
lipid storage GO:0019915 565 0.047
positive regulation of cellular metabolic process GO:0031325 178 0.047
oviposition GO:0018991 364 0.047
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.046
establishment of localization in cell GO:0051649 318 0.046
cellular component biogenesis GO:0044085 297 0.046
protein modification process GO:0036211 207 0.045
regulation of biosynthetic process GO:0009889 189 0.045
ribonucleoside triphosphate metabolic process GO:0009199 87 0.045
protein complex subunit organization GO:0071822 280 0.045
regulation of macromolecule biosynthetic process GO:0010556 189 0.045
regulation of multicellular organismal process GO:0051239 726 0.044
mitotic cell cycle process GO:1903047 194 0.044
single organism localization GO:1902578 518 0.043
carbohydrate derivative metabolic process GO:1901135 141 0.043
regulation of vulval development GO:0040028 248 0.043
cellular response to dna damage stimulus GO:0006974 41 0.043
cell part morphogenesis GO:0032990 152 0.042
cytoskeleton organization GO:0007010 339 0.042
regulation of organelle organization GO:0033043 164 0.042
sexual reproduction GO:0019953 546 0.042
lipid localization GO:0010876 573 0.041
nervous system development GO:0007399 253 0.041
head development GO:0060322 1 0.041
female gamete generation GO:0007292 254 0.040
reproductive behavior GO:0019098 387 0.040
regulation of post embryonic development GO:0048580 260 0.039
vesicle mediated transport GO:0016192 852 0.039
cellular localization GO:0051641 360 0.039
regulation of developmental process GO:0050793 684 0.038
single organism signaling GO:0044700 401 0.038
positive regulation of nucleotide catabolic process GO:0030813 28 0.038
generation of neurons GO:0048699 235 0.037
developmental growth GO:0048589 412 0.037
establishment of organelle localization GO:0051656 123 0.036
body morphogenesis GO:0010171 620 0.036
negative regulation of metabolic process GO:0009892 240 0.036
purine containing compound catabolic process GO:0072523 75 0.036
multi organism reproductive behavior GO:0044705 387 0.035
positive regulation of cellular process GO:0048522 332 0.035
single organism reproductive process GO:0044702 1196 0.035
heterocycle biosynthetic process GO:0018130 187 0.034
cellular macromolecular complex assembly GO:0034622 184 0.034
germ cell development GO:0007281 351 0.033
cellular protein modification process GO:0006464 207 0.033
negative regulation of cellular process GO:0048523 239 0.033
neurogenesis GO:0022008 236 0.033
positive regulation of transcription dna templated GO:0045893 102 0.033
signal transduction GO:0007165 317 0.032
regulation of cell proliferation GO:0042127 105 0.032
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.032
phosphate containing compound metabolic process GO:0006796 232 0.032
regulation of nematode larval development GO:0061062 260 0.031
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.031
positive regulation of growth GO:0045927 369 0.031
aging GO:0007568 812 0.030
Human
meiotic sister chromatid segregation GO:0045144 15 0.030
telomere organization GO:0032200 6 0.029
Human
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.029
axonogenesis GO:0007409 102 0.029
negative regulation of biological process GO:0048519 567 0.028
multi organism behavior GO:0051705 389 0.028
cell projection organization GO:0030030 231 0.027
growth GO:0040007 562 0.027
organonitrogen compound metabolic process GO:1901564 151 0.027
cellular response to inorganic substance GO:0071241 3 0.026
nucleoside triphosphate metabolic process GO:0009141 87 0.025
reproductive system development GO:0061458 850 0.025
positive regulation of multicellular organism growth GO:0040018 352 0.025
cellular protein metabolic process GO:0044267 279 0.025
actin cytoskeleton organization GO:0030036 184 0.025
tissue morphogenesis GO:0048729 65 0.025
nucleoside phosphate metabolic process GO:0006753 108 0.025
positive regulation of biosynthetic process GO:0009891 109 0.024
behavior GO:0007610 527 0.024
myosin filament assembly GO:0031034 138 0.023
axon development GO:0061564 163 0.023
rna interference GO:0016246 137 0.022
multicellular organismal reproductive behavior GO:0033057 384 0.022
positive regulation of macromolecule metabolic process GO:0010604 149 0.022
feminization of hermaphroditic germ line GO:0040022 34 0.022
positive regulation of developmental growth GO:0048639 354 0.022
regulation of cytoplasmic transport GO:1903649 3 0.021
polar body extrusion after meiotic divisions GO:0040038 14 0.021
regulation of growth GO:0040008 409 0.021
nucleoside catabolic process GO:0009164 78 0.021
carbohydrate derivative catabolic process GO:1901136 82 0.021
macromolecule catabolic process GO:0009057 202 0.021
negative regulation of cellular metabolic process GO:0031324 95 0.021
organic substance catabolic process GO:1901575 294 0.021
neuromuscular junction development GO:0007528 2 0.021
purine nucleoside metabolic process GO:0042278 92 0.021
purine nucleoside catabolic process GO:0006152 75 0.021
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.020
posttranscriptional gene silencing GO:0016441 143 0.020
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.020
purine ribonucleoside metabolic process GO:0046128 92 0.020
mitotic sister chromatid segregation GO:0000070 38 0.020
organic cyclic compound catabolic process GO:1901361 119 0.020
meiotic cytokinesis GO:0033206 15 0.020
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.019
defense response GO:0006952 296 0.019
single organism catabolic process GO:0044712 129 0.019
anatomical structure formation involved in morphogenesis GO:0048646 250 0.019
nucleic acid templated transcription GO:0097659 169 0.019
regulation of cell division GO:0051302 142 0.019
negative regulation of gene expression GO:0010629 217 0.018
positive regulation of nucleoside metabolic process GO:0045979 28 0.018
single organism transport GO:0044765 447 0.018
oxoacid metabolic process GO:0043436 47 0.018
regulation of multicellular organism growth GO:0040014 373 0.018
positive regulation of chromosome organization GO:2001252 2 0.018
chromosome segregation GO:0007059 180 0.018
regulation of developmental growth GO:0048638 389 0.018
negative regulation of macromolecule metabolic process GO:0010605 229 0.018
small gtpase mediated signal transduction GO:0007264 32 0.018
organelle assembly GO:0070925 214 0.018
positive regulation of rna metabolic process GO:0051254 103 0.018
multicellular organism growth GO:0035264 385 0.018
ribonucleoside catabolic process GO:0042454 77 0.017
negative regulation of post embryonic development GO:0048581 208 0.017
multi multicellular organism process GO:0044706 390 0.017
heterocycle catabolic process GO:0046700 119 0.017
ribonucleoside metabolic process GO:0009119 98 0.017
organophosphate catabolic process GO:0046434 81 0.017
ribose phosphate metabolic process GO:0019693 99 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.016
establishment of nucleus localization GO:0040023 55 0.016
organophosphate metabolic process GO:0019637 125 0.016
regulation of intracellular signal transduction GO:1902531 77 0.016
mitotic nuclear division GO:0007067 89 0.016
post embryonic organ development GO:0048569 336 0.016
meiosis ii GO:0007135 16 0.016
ribonucleoside triphosphate catabolic process GO:0009203 72 0.016
protein oligomerization GO:0051259 4 0.016
protein modification by small protein conjugation or removal GO:0070647 40 0.016
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 2 0.016
regulation of localization GO:0032879 194 0.016
actomyosin structure organization GO:0031032 154 0.015
purine ribonucleoside catabolic process GO:0046130 75 0.015
vulval development GO:0040025 333 0.015
response to chemical GO:0042221 356 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.015
gene silencing by rna GO:0031047 143 0.015
chromatin remodeling GO:0006338 2 0.015
regulation of cell communication GO:0010646 176 0.015
nucleoside metabolic process GO:0009116 99 0.015
positive regulation of gene expression GO:0010628 112 0.015
membrane organization GO:0061024 135 0.015
aromatic compound catabolic process GO:0019439 116 0.015
regulation of multicellular organismal development GO:2000026 317 0.014
nucleotide catabolic process GO:0009166 77 0.014
protein localization GO:0008104 205 0.014
ribonucleotide catabolic process GO:0009261 75 0.014
nuclear migration GO:0007097 54 0.014
positive regulation of developmental process GO:0051094 408 0.014
regulation of cellular amine metabolic process GO:0033238 0 0.014
maintenance of location in cell GO:0051651 12 0.014
nucleoside triphosphate catabolic process GO:0009143 72 0.014
purine nucleoside monophosphate catabolic process GO:0009128 28 0.014
negative regulation of developmental process GO:0051093 227 0.014
sensory organ morphogenesis GO:0090596 2 0.014
organonitrogen compound catabolic process GO:1901565 90 0.014
response to abiotic stimulus GO:0009628 152 0.014
purine ribonucleotide catabolic process GO:0009154 75 0.013
sex determination GO:0007530 60 0.013
negative regulation of gene expression epigenetic GO:0045814 2 0.013
negative regulation of nematode larval development GO:0061064 208 0.013
male anatomical structure morphogenesis GO:0090598 78 0.013
cell recognition GO:0008037 85 0.013
nucleobase containing small molecule metabolic process GO:0055086 115 0.013
nucleoside phosphate catabolic process GO:1901292 77 0.013
cellular macromolecule catabolic process GO:0044265 73 0.013
nucleotide metabolic process GO:0009117 108 0.013
posttranscriptional gene silencing by rna GO:0035194 143 0.013
positive regulation of rna biosynthetic process GO:1902680 102 0.013
localization of cell GO:0051674 313 0.013
muscle cell development GO:0055001 158 0.013
tube development GO:0035295 126 0.013
membrane invagination GO:0010324 98 0.013
atp catabolic process GO:0006200 27 0.012
response to external stimulus GO:0009605 289 0.012
ras protein signal transduction GO:0007265 31 0.012
metaphase plate congression GO:0051310 5 0.012
hermaphrodite germ line sex determination GO:0040021 48 0.012
purine nucleotide metabolic process GO:0006163 95 0.012
negative regulation of vulval development GO:0040027 206 0.012
cuticle development GO:0042335 100 0.012
regulation of chromatin modification GO:1903308 2 0.012
protein metabolic process GO:0019538 422 0.012
negative regulation of multicellular organismal process GO:0051241 236 0.012
posttranscriptional regulation of gene expression GO:0010608 166 0.012
striated muscle myosin thick filament assembly GO:0071688 138 0.011
cell projection morphogenesis GO:0048858 148 0.011
actin filament based process GO:0030029 191 0.011
myosin filament organization GO:0031033 138 0.011
organic acid metabolic process GO:0006082 47 0.011
regulation of signaling GO:0023051 172 0.011
covalent chromatin modification GO:0016569 30 0.011
skeletal muscle organ development GO:0060538 3 0.011
regulation of cellular ketone metabolic process GO:0010565 3 0.011
regulation of signal transduction GO:0009966 135 0.011
digestive tract morphogenesis GO:0048546 76 0.011
chromatin assembly GO:0031497 1 0.011
sister chromatid segregation GO:0000819 46 0.011
rna localization GO:0006403 3 0.011
regulation of nucleoside metabolic process GO:0009118 37 0.011
positive regulation of cellular biosynthetic process GO:0031328 109 0.011
regulation of gene expression epigenetic GO:0040029 163 0.011
purine nucleoside triphosphate metabolic process GO:0009144 87 0.010
mitotic cell cycle phase transition GO:0044772 13 0.010
germ line sex determination GO:0018992 51 0.010
female meiotic division GO:0007143 17 0.010
actomyosin contractile ring organization GO:0044837 1 0.010
organelle localization GO:0051640 127 0.010
positive regulation of cell cycle GO:0045787 55 0.010

smc-6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
spinocerebellar degeneration DOID:2478 0 0.014
central nervous system disease DOID:331 0 0.014
disease of anatomical entity DOID:7 0 0.014
neurodegenerative disease DOID:1289 0 0.014
nervous system disease DOID:863 0 0.014