Caenorhabditis elegans

26 known processes

ifd-1 (CELE_R04E5.10)

Protein IFD-1

ifd-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.817
er nucleus signaling pathway GO:0006984 66 0.743
Mouse
embryo development GO:0009790 3052 0.725
post embryonic development GO:0009791 2152 0.682
Worm
multicellular organismal reproductive process GO:0048609 815 0.606
Worm Fly
multicellular organism reproduction GO:0032504 819 0.604
Worm Fly
single organism signaling GO:0044700 401 0.581
Mouse Fly
signaling GO:0023052 401 0.570
Mouse Fly
single organism reproductive process GO:0044702 1196 0.502
Worm Fly
organ development GO:0048513 1102 0.410
Human Mouse Worm Fly
regulation of response to stimulus GO:0048583 243 0.399
Mouse
cell migration GO:0016477 306 0.392
Mouse
response to topologically incorrect protein GO:0035966 82 0.374
cell development GO:0048468 696 0.364
Mouse Worm
cellular component assembly GO:0022607 293 0.363
Worm Fly
receptor mediated endocytosis GO:0006898 715 0.356
Worm
developmental process involved in reproduction GO:0003006 1165 0.326
Worm Fly
single organism organelle organization GO:1902589 501 0.325
Mouse Worm Fly
cellular component morphogenesis GO:0032989 318 0.318
Worm
response to anesthetic GO:0072347 1 0.315
cellular response to topologically incorrect protein GO:0035967 76 0.304
defecation rhythm GO:0035882 3 0.290
apoptotic process GO:0006915 478 0.282
Mouse
regulation of biological quality GO:0065008 741 0.269
Fly
inactivation of mapkkk activity GO:0051390 2 0.269
development of primary sexual characteristics GO:0045137 840 0.265
Worm Fly
transport GO:0006810 1093 0.263
Mouse Worm
organ morphogenesis GO:0009887 67 0.252
Fly
ion transport GO:0006811 113 0.252
reproductive structure development GO:0048608 850 0.244
Worm Fly
growth GO:0040007 562 0.244
cellular response to unfolded protein GO:0034620 71 0.241
single organism localization GO:1902578 518 0.239
Mouse Worm Fly
multi organism reproductive process GO:0044703 867 0.236
Worm Fly
response to chemical GO:0042221 356 0.236
Human
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.229
Worm
determination of adult lifespan GO:0008340 812 0.228
Worm
endoplasmic reticulum unfolded protein response GO:0030968 66 0.226
programmed cell death GO:0012501 500 0.221
Mouse
gonad development GO:0008406 840 0.219
Worm Fly
aging GO:0007568 812 0.219
Human Zebrafish Worm Fly
response to unfolded protein GO:0006986 71 0.212
nervous system development GO:0007399 253 0.209
Fly
germ cell development GO:0007281 351 0.206
Worm
response to endoplasmic reticulum stress GO:0034976 71 0.199
nucleobase containing compound metabolic process GO:0006139 406 0.197
Fly
reproductive behavior GO:0019098 387 0.191
Worm
phosphorus metabolic process GO:0006793 232 0.186
regulation of metabolic process GO:0019222 478 0.183
Mouse Fly
macromolecule localization GO:0033036 771 0.179
Mouse Worm Fly
organelle organization GO:0006996 783 0.176
Mouse Worm Fly
cellular response to stress GO:0033554 162 0.174
Human Mouse
macromolecular complex subunit organization GO:0043933 320 0.173
Worm Fly
body morphogenesis GO:0010171 620 0.172
Worm
oviposition GO:0018991 364 0.172
Worm
positive regulation of multicellular organismal process GO:0051240 417 0.168
organelle assembly GO:0070925 214 0.167
Worm
muscle cell differentiation GO:0042692 171 0.166
Mouse Worm
signal transduction GO:0007165 317 0.166
Mouse
establishment of localization GO:0051234 1171 0.165
Mouse Worm Fly
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.162
Worm
cell projection organization GO:0030030 231 0.156
macromolecule catabolic process GO:0009057 202 0.155
Worm
ion transmembrane transport GO:0034220 91 0.151
multi organism behavior GO:0051705 389 0.150
Worm
neuron differentiation GO:0030182 217 0.148
striated muscle cell development GO:0055002 157 0.147
Mouse Worm
cytoskeleton organization GO:0007010 339 0.140
Mouse Worm Fly
regulation of multicellular organismal process GO:0051239 726 0.139
vesicle mediated transport GO:0016192 852 0.138
Worm
regulation of growth GO:0040008 409 0.136
hermaphrodite genitalia development GO:0040035 734 0.136
Worm
muscle organ morphogenesis GO:0048644 4 0.132
Fly
multi multicellular organism process GO:0044706 390 0.130
Worm
regulation of behavior GO:0050795 97 0.129
response to abiotic stimulus GO:0009628 152 0.128
Human
localization of cell GO:0051674 313 0.126
Mouse
anatomical structure formation involved in morphogenesis GO:0048646 250 0.125
Worm
multicellular organismal aging GO:0010259 812 0.123
Worm
cell motility GO:0048870 313 0.121
Mouse
multicellular organismal reproductive behavior GO:0033057 384 0.118
Worm
regulation of cell communication GO:0010646 176 0.118
Mouse
muscle structure development GO:0061061 191 0.117
Human Mouse Worm Fly
protein catabolic process GO:0030163 162 0.116
Worm
behavior GO:0007610 527 0.116
Worm Fly
gamete generation GO:0007276 461 0.114
Worm Fly
regulation of developmental process GO:0050793 684 0.114
catabolic process GO:0009056 318 0.113
Worm
positive regulation of cellular process GO:0048522 332 0.112
Human Mouse Worm
female gamete generation GO:0007292 254 0.110
organonitrogen compound metabolic process GO:1901564 151 0.110
generation of neurons GO:0048699 235 0.109
actin cytoskeleton organization GO:0030036 184 0.108
Worm Fly
regulation of developmental growth GO:0048638 389 0.108
regulation of signaling GO:0023051 172 0.107
Mouse
cellular localization GO:0051641 360 0.105
Mouse Worm Fly
regulation of signal transduction GO:0009966 135 0.104
Mouse
system process GO:0003008 136 0.102
Zebrafish
regulation of cellular component organization GO:0051128 248 0.102
Mouse Fly
locomotion GO:0040011 1634 0.100
Mouse Worm
regulation of multicellular organismal development GO:2000026 317 0.099
cellular component assembly involved in morphogenesis GO:0010927 183 0.098
Worm
actin filament based process GO:0030029 191 0.097
Worm Fly
negative regulation of biological process GO:0048519 567 0.096
Mouse Worm Fly
cellular response to organic substance GO:0071310 119 0.095
response to external stimulus GO:0009605 289 0.093
reproductive system development GO:0061458 850 0.092
Worm Fly
maintenance of location GO:0051235 580 0.091
striated muscle cell differentiation GO:0051146 158 0.091
Mouse Worm
developmental growth GO:0048589 412 0.090
cellular component biogenesis GO:0044085 297 0.090
Worm Fly
multicellular organism growth GO:0035264 385 0.090
intracellular signal transduction GO:0035556 96 0.089
chromosome organization GO:0051276 104 0.088
Fly
single organism transport GO:0044765 447 0.087
Mouse
organelle fission GO:0048285 363 0.086
Worm
molting cycle GO:0042303 281 0.084
Worm
intercellular transport GO:0010496 1 0.084
endocytosis GO:0006897 819 0.082
Worm
neuron development GO:0048666 199 0.081
positive regulation of growth GO:0045927 369 0.081
genitalia development GO:0048806 741 0.081
Worm
sex differentiation GO:0007548 909 0.080
Worm Fly
positive regulation of developmental growth GO:0048639 354 0.077
myofibril assembly GO:0030239 154 0.077
Worm
protein complex assembly GO:0006461 186 0.076
Worm Fly
death GO:0016265 547 0.076
Mouse
positive regulation of developmental process GO:0051094 408 0.076
lipid localization GO:0010876 573 0.076
regulation of multicellular organism growth GO:0040014 373 0.074
protein metabolic process GO:0019538 422 0.074
Worm
organic substance catabolic process GO:1901575 294 0.074
Worm
negative regulation of ion transmembrane transporter activity GO:0032413 3 0.074
lipid storage GO:0019915 565 0.073
regulation of cellular protein metabolic process GO:0032268 75 0.073
phosphorylation GO:0016310 116 0.073
sexual reproduction GO:0019953 546 0.072
Worm Fly
cell part morphogenesis GO:0032990 152 0.071
macromolecule modification GO:0043412 218 0.069
transmembrane transport GO:0055085 110 0.069
rna biosynthetic process GO:0032774 169 0.068
Fly
tube development GO:0035295 126 0.066
Fly
cellular response to chemical stimulus GO:0070887 129 0.065
Human
regulation of transport GO:0051049 91 0.065
inductive cell migration GO:0040039 145 0.065
negative regulation of cellular process GO:0048523 239 0.065
Mouse Worm Fly
cellular component movement GO:0006928 388 0.063
Mouse
oxoacid metabolic process GO:0043436 47 0.062
sensory organ morphogenesis GO:0090596 2 0.062
Fly
cell death GO:0008219 547 0.062
Mouse
protein phosphorylation GO:0006468 85 0.061
regulation of primary metabolic process GO:0080090 292 0.061
Mouse Fly
positive regulation of multicellular organism growth GO:0040018 352 0.060
negative regulation of ion transmembrane transport GO:0034766 3 0.059
oogenesis GO:0048477 229 0.059
positive regulation of macromolecule metabolic process GO:0010604 149 0.059
Mouse
protein complex subunit organization GO:0071822 280 0.058
Worm Fly
regulation of organelle organization GO:0033043 164 0.058
Mouse Fly
negative regulation of macromolecule metabolic process GO:0010605 229 0.058
Fly
cellular protein localization GO:0034613 75 0.057
Mouse Worm Fly
myosin filament assembly GO:0031034 138 0.057
Worm
neurogenesis GO:0022008 236 0.056
aromatic compound biosynthetic process GO:0019438 192 0.055
Fly
mitotic nuclear division GO:0007067 89 0.054
Worm
microvillus assembly GO:0030033 1 0.054
cell projection morphogenesis GO:0048858 148 0.052
synaptic transmission GO:0007268 106 0.052
nucleic acid metabolic process GO:0090304 299 0.051
Fly
striated muscle myosin thick filament assembly GO:0071688 138 0.050
Worm
cell morphogenesis involved in differentiation GO:0000904 112 0.050
negative regulation of gene expression GO:0010629 217 0.049
Fly
regulation of ion transport GO:0043269 39 0.049
response to organic substance GO:0010033 131 0.049
mapk cascade GO:0000165 31 0.049
negative regulation of metabolic process GO:0009892 240 0.048
Fly
cell surface receptor signaling pathway GO:0007166 149 0.048
Mouse
protein modification process GO:0036211 207 0.046
macromolecular complex assembly GO:0065003 193 0.046
Worm Fly
secretion GO:0046903 147 0.045
protein complex biogenesis GO:0070271 186 0.045
Worm Fly
regulation of rna metabolic process GO:0051252 173 0.044
Mouse Fly
phosphate containing compound metabolic process GO:0006796 232 0.044
establishment of localization in cell GO:0051649 318 0.044
Mouse Fly
multi organism reproductive behavior GO:0044705 387 0.044
Worm
muscle tissue development GO:0060537 1 0.043
Mouse
regulation of locomotion GO:0040012 161 0.043
Mouse
nuclear envelope reassembly GO:0031468 4 0.042
Fly
positive regulation of response to stimulus GO:0048584 55 0.042
protein localization GO:0008104 205 0.042
Mouse Worm Fly
cation transport GO:0006812 78 0.041
regulation of localization GO:0032879 194 0.041
Mouse
cell morphogenesis GO:0000902 163 0.041
positive regulation of cellular metabolic process GO:0031325 178 0.039
Mouse
negative regulation of response to stimulus GO:0048585 73 0.039
Mouse
cellular protein metabolic process GO:0044267 279 0.039
actomyosin structure organization GO:0031032 154 0.039
Worm
small molecule metabolic process GO:0044281 186 0.039
regulation of intracellular signal transduction GO:1902531 77 0.038
tissue development GO:0009888 112 0.038
Mouse Fly
muscle cell development GO:0055001 158 0.037
Mouse Worm
regulation of protein metabolic process GO:0051246 81 0.037
chromosome segregation GO:0007059 180 0.037
Worm
negative regulation of transmembrane transport GO:0034763 3 0.036
negative regulation of transporter activity GO:0032410 3 0.036
taxis GO:0042330 128 0.035
regulation of reproductive process GO:2000241 66 0.034
cellular protein complex assembly GO:0043623 178 0.034
Worm Fly
neurological system process GO:0050877 53 0.034
meiotic cell cycle GO:0051321 335 0.034
Worm
regulation of catalytic activity GO:0050790 78 0.034
gene expression GO:0010467 412 0.034
Fly
response to biotic stimulus GO:0009607 101 0.033
cellular macromolecular complex assembly GO:0034622 184 0.033
Worm Fly
nuclear pore localization GO:0051664 2 0.032
Worm Fly
cellular homeostasis GO:0019725 22 0.031
regulation of cell motility GO:2000145 57 0.031
Mouse
establishment of organelle localization GO:0051656 123 0.031
Fly
defense response GO:0006952 296 0.031
embryonic morphogenesis GO:0048598 152 0.031
regulation of macromolecule metabolic process GO:0060255 421 0.031
Mouse Fly
transcription from rna polymerase ii promoter GO:0006366 149 0.030
myosin filament organization GO:0031033 138 0.030
Worm
homeostatic process GO:0042592 51 0.029
regulation of programmed cell death GO:0043067 50 0.029
Mouse
pharyngeal pumping GO:0043050 58 0.029
biosynthetic process GO:0009058 323 0.028
Fly
regulation of cellular metabolic process GO:0031323 305 0.028
Mouse Fly
meiotic nuclear division GO:0007126 300 0.028
Worm
transcription dna templated GO:0006351 168 0.028
Fly
axon development GO:0061564 163 0.027
regulation of phosphorylation GO:0042325 45 0.027
organic substance biosynthetic process GO:1901576 323 0.026
Fly
negative regulation of signaling GO:0023057 61 0.026
Mouse
neuron projection morphogenesis GO:0048812 114 0.026
microtubule based process GO:0007017 182 0.026
Mouse Fly
cellular protein modification process GO:0006464 207 0.026
negative regulation of cation channel activity GO:2001258 2 0.025
excretion GO:0007588 49 0.025
rna metabolic process GO:0016070 228 0.025
Fly
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.025
regulation of cellular ketone metabolic process GO:0010565 3 0.025
cell cycle GO:0007049 526 0.025
Worm Fly
organic cyclic compound biosynthetic process GO:1901362 195 0.024
Fly
nucleic acid templated transcription GO:0097659 169 0.024
Fly
regulation of transferase activity GO:0051338 31 0.024
cell cycle process GO:0022402 482 0.023
Worm Fly
negative regulation of cell communication GO:0010648 61 0.023
Mouse
response to oxygen levels GO:0070482 22 0.023
Human
regulation of cell migration GO:0030334 55 0.023
Mouse
response to oxygen containing compound GO:1901700 44 0.022
apical junction assembly GO:0043297 1 0.022
negative regulation of ion transport GO:0043271 7 0.022
negative regulation of signal transduction GO:0009968 60 0.022
Mouse
regulation of defecation rhythm GO:2000746 3 0.022
hydrogen transport GO:0006818 5 0.022
cellular macromolecule localization GO:0070727 75 0.022
Mouse Worm Fly
establishment of nucleus localization GO:0040023 55 0.021
Fly
inorganic ion transmembrane transport GO:0098660 54 0.021
negative regulation of multicellular organismal process GO:0051241 236 0.021
regulation of cell death GO:0010941 65 0.021
Mouse
ion homeostasis GO:0050801 21 0.020
positive regulation of metabolic process GO:0009893 187 0.020
Mouse
regulation of cellular amine metabolic process GO:0033238 0 0.020
nucleobase containing compound biosynthetic process GO:0034654 184 0.019
Fly
carboxylic acid metabolic process GO:0019752 34 0.019
neuron projection development GO:0031175 187 0.019
negative regulation of biosynthetic process GO:0009890 65 0.019
Fly
adult behavior GO:0030534 3 0.019
Fly
regulation of cell differentiation GO:0045595 81 0.019
response to external biotic stimulus GO:0043207 101 0.019
regulation of cell cycle GO:0051726 194 0.018
Worm
cellular protein complex localization GO:0034629 3 0.018
Worm Fly
defense response to bacterium GO:0042742 86 0.018
cellular nitrogen compound biosynthetic process GO:0044271 192 0.018
Fly
regulation of phosphate metabolic process GO:0019220 81 0.018
heterocycle biosynthetic process GO:0018130 187 0.018
Fly
regulation of neuromuscular synaptic transmission GO:1900073 1 0.018
cellular biosynthetic process GO:0044249 315 0.018
Fly
digestive tract development GO:0048565 122 0.017
Fly
regulation of cytoskeleton organization GO:0051493 41 0.017
Fly
organic acid metabolic process GO:0006082 47 0.017
regulation of nematode larval development GO:0061062 260 0.017
regulation of system process GO:0044057 27 0.017
monovalent inorganic cation homeostasis GO:0055067 6 0.017
eating behavior GO:0042755 59 0.017
negative regulation of cellular metabolic process GO:0031324 95 0.016
Fly
gene silencing GO:0016458 143 0.016
Fly
neuron recognition GO:0008038 83 0.016
amine metabolic process GO:0009308 15 0.015
cell recognition GO:0008037 85 0.015
regulation of kinase activity GO:0043549 29 0.015
carbohydrate derivative metabolic process GO:1901135 141 0.015
regulation of gene expression epigenetic GO:0040029 163 0.015
Fly
cation transmembrane transport GO:0098655 59 0.015
nucleobase containing small molecule metabolic process GO:0055086 115 0.014
negative regulation of dna dependent dna replication GO:2000104 1 0.014
mitotic nuclear envelope reassembly GO:0007084 3 0.014
Fly
regulation of cellular component size GO:0032535 40 0.014
Fly
chemical homeostasis GO:0048878 29 0.014
apoptotic cell clearance GO:0043277 111 0.014
regulation of phosphorus metabolic process GO:0051174 81 0.014
lipid metabolic process GO:0006629 77 0.014
regulation of macromolecule biosynthetic process GO:0010556 189 0.014
Mouse Fly
regulation of apoptotic signaling pathway GO:2001233 1 0.014
Mouse
cell cell signaling GO:0007267 118 0.014
Fly
regulation of multi organism process GO:0043900 69 0.014
immune response GO:0006955 192 0.014
cuticle development GO:0042335 100 0.014
Worm Fly
regulation of oocyte maturation GO:1900193 7 0.013
signal transduction by phosphorylation GO:0023014 31 0.013
meiotic chromosome segregation GO:0045132 139 0.013
organic cyclic compound catabolic process GO:1901361 119 0.013
organic substance transport GO:0071702 113 0.013
Mouse
regulation of gene expression GO:0010468 366 0.013
Mouse Fly
response to other organism GO:0051707 101 0.013
cellular amine metabolic process GO:0044106 15 0.013
regulation of molecular function GO:0065009 89 0.013
positive regulation of biosynthetic process GO:0009891 109 0.012
Mouse
cation homeostasis GO:0055080 20 0.012
regulation of cellular ph GO:0030641 4 0.012
developmental growth involved in morphogenesis GO:0060560 37 0.012
positive regulation of signaling GO:0023056 66 0.012
cellular lipid metabolic process GO:0044255 40 0.012
defense response to other organism GO:0098542 100 0.012
positive regulation of transcription dna templated GO:0045893 102 0.012
Mouse
ribonucleoside monophosphate metabolic process GO:0009161 45 0.012
macromolecule biosynthetic process GO:0009059 250 0.012
Fly
response to bacterium GO:0009617 86 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.011
Mouse
innate immune response GO:0045087 190 0.011
regulation of vulval development GO:0040028 248 0.011
protein localization to basolateral plasma membrane GO:1903361 7 0.011
negative regulation of developmental process GO:0051093 227 0.011
spermatogenesis GO:0007283 41 0.011
Fly
regulation of protein kinase activity GO:0045859 28 0.011
axonogenesis GO:0007409 102 0.011
nuclear pore distribution GO:0031081 2 0.011
Worm Fly
skeletal muscle organ development GO:0060538 3 0.011
endomembrane system organization GO:0010256 22 0.011
Mouse Fly
male gamete generation GO:0048232 41 0.011
Fly
membrane organization GO:0061024 135 0.011
Mouse Fly
axonal fasciculation GO:0007413 79 0.011
regulation of protein serine threonine kinase activity GO:0071900 18 0.011
proteolysis GO:0006508 61 0.011
nucleotide metabolic process GO:0009117 108 0.011
cellular ketone metabolic process GO:0042180 14 0.011
single organism behavior GO:0044708 83 0.011
Fly
establishment of protein localization to membrane GO:0090150 3 0.011
defecation GO:0030421 47 0.011
positive regulation of cell communication GO:0010647 69 0.011
cellular response to inorganic substance GO:0071241 3 0.011
regulation of cell development GO:0060284 49 0.011
regulation of cellular component movement GO:0051270 62 0.011
Mouse
response to inorganic substance GO:0010035 50 0.011
cellular amino acid metabolic process GO:0006520 15 0.010
regulation of nitrogen compound metabolic process GO:0051171 222 0.010
Mouse Fly
regulation of chromosome segregation GO:0051983 20 0.010
Worm
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.010
establishment or maintenance of cell polarity GO:0007163 63 0.010
Mouse
peptidyl amino acid modification GO:0018193 58 0.010
positive regulation of cysteine type endopeptidase activity GO:2001056 3 0.010
regulation of neurogenesis GO:0050767 40 0.010

ifd-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.404
Human
muscular disease DOID:0080000 0 0.404
Human
heart disease DOID:114 0 0.404
Human
cardiomyopathy DOID:0050700 0 0.404
Human
disease of anatomical entity DOID:7 0 0.404
Human
cardiovascular system disease DOID:1287 0 0.404
Human
musculoskeletal system disease DOID:17 0 0.404
Human
muscle tissue disease DOID:66 0 0.404
Human
congenital muscular dystrophy DOID:0050557 0 0.305
Human
muscular dystrophy DOID:9884 0 0.305
Human
progeria DOID:3911 0 0.070
Human
dilated cardiomyopathy DOID:12930 0 0.049
Human
intrinsic cardiomyopathy DOID:0060036 0 0.049
Human
lipodystrophy DOID:811 0 0.041
Human
skin disease DOID:37 0 0.041
Human
integumentary system disease DOID:16 0 0.041
Human
limb girdle muscular dystrophy DOID:11724 0 0.040
Human
nervous system disease DOID:863 0 0.020
Human
neuromuscular disease DOID:440 0 0.014
Human
charcot marie tooth disease type 2 DOID:0050539 0 0.014
Human
charcot marie tooth disease DOID:10595 0 0.014
Human
neuropathy DOID:870 0 0.014
Human