Caenorhabditis elegans

77 known processes

che-3 (CELE_F18C12.1)

Protein CHE-3

che-3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cilium assembly GO:0042384 28 0.972
cilium organization GO:0044782 32 0.966
cellular component morphogenesis GO:0032989 318 0.926
cilium morphogenesis GO:0060271 33 0.772
anatomical structure formation involved in morphogenesis GO:0048646 250 0.765
cell part morphogenesis GO:0032990 152 0.738
cell projection morphogenesis GO:0048858 148 0.717
establishment of localization GO:0051234 1171 0.686
Mouse Fly
cell surface receptor signaling pathway GO:0007166 149 0.686
embryo development ending in birth or egg hatching GO:0009792 2992 0.681
regulation of signaling GO:0023051 172 0.626
single organism organelle organization GO:1902589 501 0.578
embryo development GO:0009790 3052 0.569
Mouse
organelle organization GO:0006996 783 0.568
organ development GO:0048513 1102 0.557
Mouse
regulation of response to stimulus GO:0048583 243 0.533
locomotion GO:0040011 1634 0.517
cellular component assembly involved in morphogenesis GO:0010927 183 0.498
intraciliary transport GO:0042073 12 0.479
Mouse Fly
regulation of developmental process GO:0050793 684 0.474
cgmp biosynthetic process GO:0006182 2 0.473
post embryonic development GO:0009791 2152 0.451
regulation of cation channel activity GO:2001257 3 0.447
regulation of metabolic process GO:0019222 478 0.416
response to chemical GO:0042221 356 0.411
chemotaxis GO:0006935 120 0.410
signaling GO:0023052 401 0.401
nervous system development GO:0007399 253 0.384
Mouse
response to external stimulus GO:0009605 289 0.367
Fly
organelle assembly GO:0070925 214 0.363
gene expression GO:0010467 412 0.339
Mouse
transport GO:0006810 1093 0.336
Mouse Fly
cell morphogenesis GO:0000902 163 0.336
defecation rhythm GO:0035882 3 0.333
regulation of cell differentiation GO:0045595 81 0.329
inactivation of mapkkk activity GO:0051390 2 0.328
positive regulation of cellular process GO:0048522 332 0.309
Mouse
pattern specification process GO:0007389 59 0.303
Mouse
protein complex subunit organization GO:0071822 280 0.300
epithelial cell proliferation GO:0050673 1 0.293
gonad development GO:0008406 840 0.282
intercellular transport GO:0010496 1 0.280
single organism signaling GO:0044700 401 0.279
multicellular organism reproduction GO:0032504 819 0.278
Fly
establishment of localization in cell GO:0051649 318 0.273
Mouse Fly
growth GO:0040007 562 0.272
reproductive structure development GO:0048608 850 0.264
regulation of signal transduction GO:0009966 135 0.262
response to anesthetic GO:0072347 1 0.261
determination of adult lifespan GO:0008340 812 0.256
regulation of neuron differentiation GO:0045664 40 0.252
single organism reproductive process GO:0044702 1196 0.248
behavior GO:0007610 527 0.246
gamete generation GO:0007276 461 0.240
cell development GO:0048468 696 0.239
single organism transport GO:0044765 447 0.231
Mouse Fly
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 5 0.230
reproductive system development GO:0061458 850 0.230
negative regulation of biological process GO:0048519 567 0.227
regulation of macromolecule metabolic process GO:0060255 421 0.227
negative regulation of cellular process GO:0048523 239 0.226
embryonic morphogenesis GO:0048598 152 0.225
Mouse
cell projection assembly GO:0030031 35 0.223
regulation of biological quality GO:0065008 741 0.219
cellular component biogenesis GO:0044085 297 0.219
cellular response to chemical stimulus GO:0070887 129 0.219
regulation of axonogenesis GO:0050770 24 0.218
multicellular organismal aging GO:0010259 812 0.213
cellular component assembly GO:0022607 293 0.210
cytoskeleton organization GO:0007010 339 0.205
multi organism reproductive process GO:0044703 867 0.204
Fly
taxis GO:0042330 128 0.202
regulation of developmental growth GO:0048638 389 0.201
negative regulation of cation channel activity GO:2001258 2 0.200
neuron differentiation GO:0030182 217 0.199
Mouse
regulation of multicellular organismal process GO:0051239 726 0.199
neuron projection extension GO:1990138 37 0.196
axonogenesis GO:0007409 102 0.195
developmental growth GO:0048589 412 0.192
genitalia development GO:0048806 741 0.190
nonmotile primary cilium assembly GO:0035058 18 0.181
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.180
dauer larval development GO:0040024 92 0.178
cell projection organization GO:0030030 231 0.174
regulation of neuromuscular synaptic transmission GO:1900073 1 0.172
hermaphrodite genitalia development GO:0040035 734 0.171
regulation of primary metabolic process GO:0080090 292 0.164
multicellular organismal reproductive process GO:0048609 815 0.159
Fly
negative regulation of multicellular organismal process GO:0051241 236 0.154
vesicle mediated transport GO:0016192 852 0.153
programmed cell death GO:0012501 500 0.151
regulation of epithelial cell proliferation GO:0050678 1 0.151
enzyme linked receptor protein signaling pathway GO:0007167 50 0.150
endocytosis GO:0006897 819 0.148
single organism localization GO:1902578 518 0.147
Mouse Fly
developmental process involved in reproduction GO:0003006 1165 0.146
germ cell development GO:0007281 351 0.146
development of primary sexual characteristics GO:0045137 840 0.144
regulation of growth GO:0040008 409 0.140
aging GO:0007568 812 0.140
death GO:0016265 547 0.140
macromolecule localization GO:0033036 771 0.137
regulation of gene expression GO:0010468 366 0.137
receptor mediated endocytosis GO:0006898 715 0.134
cellular component movement GO:0006928 388 0.133
regulation of cellular metabolic process GO:0031323 305 0.129
body morphogenesis GO:0010171 620 0.127
sensory organ morphogenesis GO:0090596 2 0.124
head development GO:0060322 1 0.122
Mouse
generation of neurons GO:0048699 235 0.120
Mouse
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 6 0.118
ion transmembrane transport GO:0034220 91 0.116
myofibril assembly GO:0030239 154 0.115
regulation of cell communication GO:0010646 176 0.115
cell death GO:0008219 547 0.113
female gamete generation GO:0007292 254 0.112
signal transduction GO:0007165 317 0.112
apoptotic process GO:0006915 478 0.111
cellular response to endogenous stimulus GO:0071495 32 0.108
system process GO:0003008 136 0.108
Fly
positive regulation of response to stimulus GO:0048584 55 0.108
Mouse
negative regulation of signal transduction GO:0009968 60 0.108
catabolic process GO:0009056 318 0.107
regulation of defecation rhythm GO:2000746 3 0.106
multicellular organismal reproductive behavior GO:0033057 384 0.105
Fly
sex differentiation GO:0007548 909 0.105
oviposition GO:0018991 364 0.104
response to organic substance GO:0010033 131 0.103
cellular response to organic substance GO:0071310 119 0.102
negative regulation of transporter activity GO:0032410 3 0.100
calcium mediated signaling GO:0019722 3 0.100
phosphate containing compound metabolic process GO:0006796 232 0.099
actin cytoskeleton organization GO:0030036 184 0.098
cellular localization GO:0051641 360 0.097
Mouse Fly
muscle structure development GO:0061061 191 0.097
ion transport GO:0006811 113 0.097
macromolecular complex subunit organization GO:0043933 320 0.095
neurogenesis GO:0022008 236 0.094
Mouse
positive regulation of developmental growth GO:0048639 354 0.093
sexual reproduction GO:0019953 546 0.092
Fly
regulation of extent of cell growth GO:0061387 20 0.092
protein metabolic process GO:0019538 422 0.091
Mouse
positive regulation of multicellular organismal process GO:0051240 417 0.091
multicellular organism growth GO:0035264 385 0.090
regulation of axon extension GO:0030516 20 0.089
oogenesis GO:0048477 229 0.089
positive regulation of developmental process GO:0051094 408 0.086
regulation of nitrogen compound metabolic process GO:0051171 222 0.086
regulation of cell development GO:0060284 49 0.085
striated muscle cell development GO:0055002 157 0.085
positive regulation of multicellular organism growth GO:0040018 352 0.085
regulation of rna metabolic process GO:0051252 173 0.084
multi organism reproductive behavior GO:0044705 387 0.084
Fly
transcription from rna polymerase ii promoter GO:0006366 149 0.083
actin filament based process GO:0030029 191 0.081
nucleobase containing compound metabolic process GO:0006139 406 0.078
aromatic compound biosynthetic process GO:0019438 192 0.078
nucleic acid metabolic process GO:0090304 299 0.078
single organism intracellular transport GO:1902582 70 0.076
Mouse Fly
protein localization GO:0008104 205 0.075
multi multicellular organism process GO:0044706 390 0.074
Fly
neurological system process GO:0050877 53 0.073
Fly
muscle cell differentiation GO:0042692 171 0.073
microtubule based movement GO:0007018 33 0.072
Mouse Fly
axon development GO:0061564 163 0.070
protein modification process GO:0036211 207 0.070
regulation of locomotion GO:0040012 161 0.069
lipid localization GO:0010876 573 0.069
regulation of oocyte maturation GO:1900193 7 0.068
cellular protein metabolic process GO:0044267 279 0.067
regulation of cell morphogenesis GO:0022604 40 0.067
cellular protein complex assembly GO:0043623 178 0.066
regulation of multicellular organism growth GO:0040014 373 0.066
determination of left right symmetry GO:0007368 9 0.066
Mouse
muscle tissue development GO:0060537 1 0.065
actomyosin structure organization GO:0031032 154 0.065
axon extension GO:0048675 37 0.065
regulation of intracellular signal transduction GO:1902531 77 0.064
microtubule based process GO:0007017 182 0.064
Mouse Fly
negative regulation of response to stimulus GO:0048585 73 0.062
striated muscle myosin thick filament assembly GO:0071688 138 0.061
regulation of multicellular organismal development GO:2000026 317 0.061
lipid storage GO:0019915 565 0.061
negative regulation of developmental process GO:0051093 227 0.061
cell proliferation GO:0008283 116 0.059
protein complex biogenesis GO:0070271 186 0.058
cell cycle process GO:0022402 482 0.058
maintenance of location GO:0051235 580 0.057
negative regulation of ion transmembrane transport GO:0034766 3 0.055
neuron projection development GO:0031175 187 0.053
rna metabolic process GO:0016070 228 0.053
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.053
negative regulation of signaling GO:0023057 61 0.053
reproductive behavior GO:0019098 387 0.052
Fly
molting cycle GO:0042303 281 0.052
cell cell signaling GO:0007267 118 0.051
cell motility GO:0048870 313 0.051
regulation of cell projection organization GO:0031344 38 0.050
striated muscle cell differentiation GO:0051146 158 0.050
negative regulation of cell communication GO:0010648 61 0.049
rna biosynthetic process GO:0032774 169 0.049
negative regulation of ion transmembrane transporter activity GO:0032413 3 0.047
regulation of behavior GO:0050795 97 0.047
protein complex assembly GO:0006461 186 0.047
positive regulation of cellular metabolic process GO:0031325 178 0.047
phosphorus metabolic process GO:0006793 232 0.046
muscle cell development GO:0055001 158 0.046
cellular response to transforming growth factor beta stimulus GO:0071560 13 0.045
organic cyclic compound biosynthetic process GO:1901362 195 0.045
epithelial tube morphogenesis GO:0060562 1 0.045
organic substance catabolic process GO:1901575 294 0.045
cellular protein modification process GO:0006464 207 0.044
positive regulation of growth GO:0045927 369 0.044
regulation of transport GO:0051049 91 0.043
regulation of nucleic acid templated transcription GO:1903506 165 0.043
macromolecule modification GO:0043412 218 0.043
regulation of cell size GO:0008361 30 0.042
single organism behavior GO:0044708 83 0.042
regulation of neuron projection development GO:0010975 31 0.042
intracellular signal transduction GO:0035556 96 0.042
regulation of cellular component organization GO:0051128 248 0.042
response to abiotic stimulus GO:0009628 152 0.041
Fly
regulation of reproductive process GO:2000241 66 0.041
multi organism behavior GO:0051705 389 0.041
Fly
nucleobase containing compound biosynthetic process GO:0034654 184 0.041
regulation of organelle organization GO:0033043 164 0.040
cyclic nucleotide biosynthetic process GO:0009190 2 0.040
determination of bilateral symmetry GO:0009855 9 0.040
Mouse
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 9 0.040
macromolecular complex assembly GO:0065003 193 0.040
cellular macromolecular complex assembly GO:0034622 184 0.039
positive regulation of cellular biosynthetic process GO:0031328 109 0.039
phosphorylation GO:0016310 116 0.039
oocyte differentiation GO:0009994 45 0.039
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.039
synaptic transmission GO:0007268 106 0.039
regulation of multi organism process GO:0043900 69 0.038
insulin receptor signaling pathway GO:0008286 14 0.037
tube development GO:0035295 126 0.037
negative regulation of macromolecule metabolic process GO:0010605 229 0.037
establishment of mitotic spindle orientation GO:0000132 28 0.037
negative regulation of metabolic process GO:0009892 240 0.037
myosin filament organization GO:0031033 138 0.037
macromolecule biosynthetic process GO:0009059 250 0.036
myosin filament assembly GO:0031034 138 0.036
protein localization to cilium GO:0061512 10 0.035
negative regulation of cellular metabolic process GO:0031324 95 0.035
small molecule metabolic process GO:0044281 186 0.035
cell division GO:0051301 262 0.035
cellular biosynthetic process GO:0044249 315 0.034
tissue development GO:0009888 112 0.034
macromolecule catabolic process GO:0009057 202 0.034
post embryonic organ development GO:0048569 336 0.034
regulation of localization GO:0032879 194 0.033
embryonic body morphogenesis GO:0010172 49 0.032
microtubule based transport GO:0010970 19 0.032
Mouse Fly
regulation of cell proliferation GO:0042127 105 0.032
organic substance biosynthetic process GO:1901576 323 0.032
protein catabolic process GO:0030163 162 0.032
cellular nitrogen compound biosynthetic process GO:0044271 192 0.032
chemosensory behavior GO:0007635 33 0.032
secretion GO:0046903 147 0.031
developmental maturation GO:0021700 26 0.031
localization of cell GO:0051674 313 0.031
biosynthetic process GO:0009058 323 0.031
nucleic acid templated transcription GO:0097659 169 0.031
epithelium development GO:0060429 68 0.030
positive regulation of cell communication GO:0010647 69 0.030
Mouse
protein phosphorylation GO:0006468 85 0.030
negative regulation of transmembrane transport GO:0034763 3 0.030
transmembrane transport GO:0055085 110 0.030
response to transforming growth factor beta GO:0071559 13 0.030
response to peptide hormone GO:0043434 14 0.030
neuron development GO:0048666 199 0.029
positive regulation of cell projection organization GO:0031346 4 0.028
regulation of anatomical structure size GO:0090066 46 0.028
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.027
cell migration GO:0016477 306 0.027
positive regulation of transcription dna templated GO:0045893 102 0.027
positive chemotaxis GO:0050918 3 0.027
neuron projection morphogenesis GO:0048812 114 0.026
wnt signaling pathway GO:0016055 27 0.026
cyclic purine nucleotide metabolic process GO:0052652 2 0.026
positive regulation of rna biosynthetic process GO:1902680 102 0.026
developmental growth involved in morphogenesis GO:0060560 37 0.026
cellular response to growth factor stimulus GO:0071363 18 0.025
skeletal muscle organ development GO:0060538 3 0.025
cellular response to nitrogen compound GO:1901699 24 0.024
ribonucleotide metabolic process GO:0009259 99 0.023
positive regulation of neuron differentiation GO:0045666 4 0.023
regulation of synaptic transmission GO:0050804 34 0.023
response to insulin GO:0032868 14 0.023
developmental cell growth GO:0048588 39 0.023
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.023
oocyte development GO:0048599 44 0.023
regulation of cell morphogenesis involved in differentiation GO:0010769 29 0.022
response to heat GO:0009408 50 0.022
cell cycle GO:0007049 526 0.022
regulation of protein metabolic process GO:0051246 81 0.022
cyclic nucleotide metabolic process GO:0009187 2 0.022
cell maturation GO:0048469 26 0.022
hindgut development GO:0061525 3 0.022
purine containing compound metabolic process GO:0072521 95 0.022
posttranscriptional gene silencing by rna GO:0035194 143 0.022
eating behavior GO:0042755 59 0.022
response to oxygen containing compound GO:1901700 44 0.021
mechanosensory behavior GO:0007638 25 0.021
Fly
ribonucleoside metabolic process GO:0009119 98 0.021
digestive tract development GO:0048565 122 0.021
regulation of cellular component size GO:0032535 40 0.021
small gtpase mediated signal transduction GO:0007264 32 0.021
regulation of neurogenesis GO:0050767 40 0.021
heterocycle biosynthetic process GO:0018130 187 0.021
vulval location GO:0034608 6 0.021
regulation of wnt signaling pathway GO:0030111 9 0.020
positive regulation of neurogenesis GO:0050769 4 0.020
regulation of nervous system development GO:0051960 41 0.020
neuromuscular synaptic transmission GO:0007274 6 0.020
negative chemotaxis GO:0050919 1 0.020
regulation of macromolecule biosynthetic process GO:0010556 189 0.020
organ morphogenesis GO:0009887 67 0.019
neuron projection guidance GO:0097485 82 0.019
engulfment of apoptotic cell GO:0043652 94 0.019
response to organonitrogen compound GO:0010243 15 0.018
positive regulation of neuron projection development GO:0010976 4 0.018
cellular macromolecule biosynthetic process GO:0034645 247 0.018
feeding behavior GO:0007631 70 0.018
regulation of cell projection assembly GO:0060491 3 0.018
response to extracellular stimulus GO:0009991 38 0.018
regulation of feeding behavior GO:0060259 38 0.018
organelle localization GO:0051640 127 0.018
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 16 0.017
cellular response to organonitrogen compound GO:0071417 14 0.017
motor neuron axon guidance GO:0008045 13 0.017
regulation of catalytic activity GO:0050790 78 0.017
positive regulation of macromolecule metabolic process GO:0010604 149 0.017
phagocytosis GO:0006909 115 0.017
response to nitrogen compound GO:1901698 25 0.017
notch signaling pathway GO:0007219 22 0.017
collagen and cuticulin based cuticle development GO:0040002 99 0.017
organelle fission GO:0048285 363 0.017
regulation of ion transmembrane transport GO:0034765 19 0.017
excretion GO:0007588 49 0.017
regulation of nematode larval development GO:0061062 260 0.017
organic cyclic compound catabolic process GO:1901361 119 0.016
cgmp metabolic process GO:0046068 2 0.016
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.015
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.015
aromatic compound catabolic process GO:0019439 116 0.015
purine ribonucleoside metabolic process GO:0046128 92 0.015
skin development GO:0043588 24 0.015
cellular catabolic process GO:0044248 199 0.015
positive regulation of rna metabolic process GO:0051254 103 0.015
transcription dna templated GO:0006351 168 0.015
establishment of organelle localization GO:0051656 123 0.015
apoptotic cell clearance GO:0043277 111 0.015
regulation of cellular protein metabolic process GO:0032268 75 0.015
phagocytosis engulfment GO:0006911 98 0.014
negative regulation of gene expression GO:0010629 217 0.014
regulation of transcription dna templated GO:0006355 164 0.014
vulval development GO:0040025 333 0.014
hyperosmotic response GO:0006972 19 0.014
cellular response to abiotic stimulus GO:0071214 4 0.014
negative regulation of neurogenesis GO:0050768 4 0.014
organonitrogen compound metabolic process GO:1901564 151 0.014
positive regulation of gene expression GO:0010628 112 0.014
regulation of cellular biosynthetic process GO:0031326 189 0.014
cell morphogenesis involved in differentiation GO:0000904 112 0.014
receptor localization to nonmotile primary cilium GO:0097500 7 0.013
membrane invagination GO:0010324 98 0.013
defecation GO:0030421 47 0.013
regulation of rna biosynthetic process GO:2001141 165 0.013
negative regulation of wnt signaling pathway GO:0030178 6 0.013
regulation of cytoplasmic transport GO:1903649 3 0.013
regulation of insulin receptor signaling pathway GO:0046626 6 0.013
signal transduction by phosphorylation GO:0023014 31 0.013
rna interference GO:0016246 137 0.013
negative regulation of cell maturation GO:1903430 5 0.013
response to wounding GO:0009611 4 0.013
positive regulation of metabolic process GO:0009893 187 0.013
organophosphate metabolic process GO:0019637 125 0.012
regulation of phosphorus metabolic process GO:0051174 81 0.012
tissue morphogenesis GO:0048729 65 0.012
regulation of biosynthetic process GO:0009889 189 0.012
response to endogenous stimulus GO:0009719 33 0.012
regulation of striated muscle contraction GO:0006942 4 0.012
negative regulation of response to external stimulus GO:0032102 3 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.012
cuticle development GO:0042335 100 0.012
epithelial cell morphogenesis GO:0003382 2 0.012
digestive system development GO:0055123 122 0.012
regulation of ion transport GO:0043269 39 0.012
regulation of canonical wnt signaling pathway GO:0060828 1 0.012
spindle organization GO:0007051 92 0.012
regulation of cellular ketone metabolic process GO:0010565 3 0.012
regulation of pharyngeal pumping GO:0043051 36 0.012
regulation of nucleocytoplasmic transport GO:0046822 3 0.011
organonitrogen compound biosynthetic process GO:1901566 44 0.011
regulation of response to wounding GO:1903034 1 0.011
response to osmotic stress GO:0006970 29 0.011
establishment of protein localization GO:0045184 50 0.011
response to temperature stimulus GO:0009266 66 0.011
establishment of spindle orientation GO:0051294 34 0.011
response to growth factor GO:0070848 18 0.011
regulation of phosphorylation GO:0042325 45 0.011
inductive cell migration GO:0040039 145 0.011
establishment of cell polarity GO:0030010 46 0.011
regulation of molecular function GO:0065009 89 0.011
cytokinesis GO:0000910 80 0.011
nucleoside phosphate metabolic process GO:0006753 108 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
carbohydrate derivative metabolic process GO:1901135 141 0.011
meiotic cell cycle process GO:1903046 170 0.011
response to drug GO:0042493 14 0.011
synaptic growth at neuromuscular junction GO:0051124 1 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.010
positive regulation of protein transport GO:0051222 4 0.010
rrna processing GO:0006364 3 0.010
gene silencing by rna GO:0031047 143 0.010
membrane organization GO:0061024 135 0.010
cellular response to hormone stimulus GO:0032870 14 0.010
cell growth GO:0016049 44 0.010
protein localization to nonmotile primary cilium GO:0097499 9 0.010
muscle organ morphogenesis GO:0048644 4 0.010
cytoskeleton dependent cytokinesis GO:0061640 35 0.010
regulation of anatomical structure morphogenesis GO:0022603 51 0.010
regulation of nuclear division GO:0051783 115 0.010
response to acid chemical GO:0001101 4 0.010
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.010
ovulation GO:0030728 33 0.010
negative regulation of ion transport GO:0043271 7 0.010

che-3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.019
nervous system disease DOID:863 0 0.012
disease of metabolism DOID:0014667 0 0.010