Caenorhabditis elegans

95 known processes

che-1 (CELE_C55B7.12)

Protein CHE-1

che-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.582
cgmp biosynthetic process GO:0006182 2 0.425
response to external stimulus GO:0009605 289 0.406
neurogenesis GO:0022008 236 0.382
embryo development GO:0009790 3052 0.351
establishment of localization GO:0051234 1171 0.341
determination of adult lifespan GO:0008340 812 0.304
transport GO:0006810 1093 0.301
regulation of developmental process GO:0050793 684 0.300
regulation of multicellular organismal process GO:0051239 726 0.282
regulation of axon extension GO:0030516 20 0.275
locomotion GO:0040011 1634 0.268
cell morphogenesis GO:0000902 163 0.261
response to chemical GO:0042221 356 0.255
heterocycle biosynthetic process GO:0018130 187 0.254
generation of neurons GO:0048699 235 0.253
behavior GO:0007610 527 0.248
post embryonic development GO:0009791 2152 0.245
regulation of axonogenesis GO:0050770 24 0.241
regulation of developmental growth GO:0048638 389 0.228
chemotaxis GO:0006935 120 0.225
cell development GO:0048468 696 0.218
cellular component morphogenesis GO:0032989 318 0.217
regulation of growth GO:0040008 409 0.215
cell projection morphogenesis GO:0048858 148 0.200
single organism reproductive process GO:0044702 1196 0.195
signaling GO:0023052 401 0.193
axon extension GO:0048675 37 0.188
cellular response to chemical stimulus GO:0070887 129 0.186
aging GO:0007568 812 0.185
regulation of neuron differentiation GO:0045664 40 0.181
cyclic nucleotide biosynthetic process GO:0009190 2 0.179
neuron projection extension GO:1990138 37 0.176
gene expression GO:0010467 412 0.167
vesicle mediated transport GO:0016192 852 0.164
body morphogenesis GO:0010171 620 0.161
developmental growth GO:0048589 412 0.157
cellular biosynthetic process GO:0044249 315 0.154
regulation of cellular component size GO:0032535 40 0.151
regulation of extent of cell growth GO:0061387 20 0.151
anatomical structure formation involved in morphogenesis GO:0048646 250 0.141
regulation of metabolic process GO:0019222 478 0.141
axonogenesis GO:0007409 102 0.139
single organism localization GO:1902578 518 0.135
system process GO:0003008 136 0.134
gonad development GO:0008406 840 0.134
organ development GO:0048513 1102 0.130
regulation of biological quality GO:0065008 741 0.130
single organism transport GO:0044765 447 0.129
single organism signaling GO:0044700 401 0.127
endocytosis GO:0006897 819 0.123
multicellular organismal aging GO:0010259 812 0.122
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 9 0.120
negative regulation of cation channel activity GO:2001258 2 0.117
growth GO:0040007 562 0.113
taxis GO:0042330 128 0.113
multi organism reproductive process GO:0044703 867 0.113
macromolecule localization GO:0033036 771 0.112
multi organism reproductive behavior GO:0044705 387 0.110
positive chemotaxis GO:0050918 3 0.104
embryonic morphogenesis GO:0048598 152 0.104
cell surface receptor signaling pathway GO:0007166 149 0.101
positive regulation of cellular process GO:0048522 332 0.101
cellular component assembly involved in morphogenesis GO:0010927 183 0.100
chemosensory behavior GO:0007635 33 0.100
nervous system development GO:0007399 253 0.099
multicellular organismal reproductive behavior GO:0033057 384 0.099
development of primary sexual characteristics GO:0045137 840 0.097
reproductive structure development GO:0048608 850 0.096
developmental process involved in reproduction GO:0003006 1165 0.096
regulation of cellular component organization GO:0051128 248 0.095
cell motility GO:0048870 313 0.095
axon development GO:0061564 163 0.093
signal transduction GO:0007165 317 0.092
regulation of anatomical structure size GO:0090066 46 0.092
olfactory behavior GO:0042048 27 0.091
regulation of cell development GO:0060284 49 0.090
nucleobase containing compound biosynthetic process GO:0034654 184 0.089
neuron projection development GO:0031175 187 0.086
regulation of macromolecule metabolic process GO:0060255 421 0.085
cell morphogenesis involved in differentiation GO:0000904 112 0.085
positive regulation of signal transduction GO:0009967 40 0.083
nucleic acid metabolic process GO:0090304 299 0.083
regulation of cell size GO:0008361 30 0.083
regulation of neuron projection development GO:0010975 31 0.082
dauer larval development GO:0040024 92 0.082
organic cyclic compound biosynthetic process GO:1901362 195 0.081
regulation of cell morphogenesis involved in differentiation GO:0010769 29 0.080
response to anesthetic GO:0072347 1 0.079
neuron projection morphogenesis GO:0048812 114 0.079
regulation of signal transduction GO:0009966 135 0.079
receptor mediated endocytosis GO:0006898 715 0.079
regulation of gene expression GO:0010468 366 0.077
cgmp metabolic process GO:0046068 2 0.075
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.075
sex differentiation GO:0007548 909 0.075
multicellular organism reproduction GO:0032504 819 0.074
single organism organelle organization GO:1902589 501 0.074
biosynthetic process GO:0009058 323 0.073
oviposition GO:0018991 364 0.073
sexual reproduction GO:0019953 546 0.073
cell growth GO:0016049 44 0.073
negative chemotaxis GO:0050919 1 0.072
organic substance biosynthetic process GO:1901576 323 0.072
phosphorus metabolic process GO:0006793 232 0.071
phosphate containing compound metabolic process GO:0006796 232 0.070
maintenance of location GO:0051235 580 0.069
establishment of localization in cell GO:0051649 318 0.069
multicellular organismal reproductive process GO:0048609 815 0.069
lipid localization GO:0010876 573 0.068
cell fate commitment GO:0045165 139 0.068
multi organism behavior GO:0051705 389 0.068
gamete generation GO:0007276 461 0.068
reproductive system development GO:0061458 850 0.066
muscle cell development GO:0055001 158 0.066
single organism behavior GO:0044708 83 0.066
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.066
cellular response to organic substance GO:0071310 119 0.066
cell projection organization GO:0030030 231 0.065
cellular response to endogenous stimulus GO:0071495 32 0.065
regulation of gene expression epigenetic GO:0040029 163 0.065
positive regulation of developmental process GO:0051094 408 0.064
lipid storage GO:0019915 565 0.064
multicellular organism growth GO:0035264 385 0.063
sensory perception GO:0007600 27 0.063
neuron development GO:0048666 199 0.063
negative regulation of biological process GO:0048519 567 0.062
cell part morphogenesis GO:0032990 152 0.062
response to organic substance GO:0010033 131 0.061
positive regulation of multicellular organism growth GO:0040018 352 0.061
positive regulation of developmental growth GO:0048639 354 0.059
developmental cell growth GO:0048588 39 0.059
regulation of neurogenesis GO:0050767 40 0.059
nucleobase containing compound metabolic process GO:0006139 406 0.059
positive regulation of metabolic process GO:0009893 187 0.058
actin cytoskeleton organization GO:0030036 184 0.058
regulation of cell differentiation GO:0045595 81 0.057
regulation of cell communication GO:0010646 176 0.057
multi multicellular organism process GO:0044706 390 0.056
regulation of primary metabolic process GO:0080090 292 0.056
programmed cell death GO:0012501 500 0.056
cellular component assembly GO:0022607 293 0.055
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 5 0.055
regulation of response to stimulus GO:0048583 243 0.055
regulation of nervous system development GO:0051960 41 0.055
sensory organ morphogenesis GO:0090596 2 0.054
regulation of multicellular organismal development GO:2000026 317 0.054
germ cell development GO:0007281 351 0.053
positive regulation of multicellular organismal process GO:0051240 417 0.053
neuron differentiation GO:0030182 217 0.052
muscle structure development GO:0061061 191 0.052
cellular protein complex assembly GO:0043623 178 0.051
regulation of cell morphogenesis GO:0022604 40 0.051
striated muscle cell development GO:0055002 157 0.051
organelle organization GO:0006996 783 0.051
oogenesis GO:0048477 229 0.051
reproductive behavior GO:0019098 387 0.050
regulation of signaling GO:0023051 172 0.050
regulation of multicellular organism growth GO:0040014 373 0.049
enzyme linked receptor protein signaling pathway GO:0007167 50 0.048
macromolecule biosynthetic process GO:0009059 250 0.048
ribonucleotide metabolic process GO:0009259 99 0.047
cytoskeleton organization GO:0007010 339 0.047
negative regulation of multicellular organismal process GO:0051241 236 0.047
cell death GO:0008219 547 0.047
posttranscriptional gene silencing by rna GO:0035194 143 0.047
regulation of anatomical structure morphogenesis GO:0022603 51 0.047
protein metabolic process GO:0019538 422 0.046
cyclic purine nucleotide metabolic process GO:0052652 2 0.046
actomyosin structure organization GO:0031032 154 0.046
myofibril assembly GO:0030239 154 0.045
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.044
organelle assembly GO:0070925 214 0.044
developmental growth involved in morphogenesis GO:0060560 37 0.044
genitalia development GO:0048806 741 0.044
apoptotic process GO:0006915 478 0.044
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.043
negative regulation of developmental process GO:0051093 227 0.043
cellular macromolecular complex assembly GO:0034622 184 0.042
embryonic body morphogenesis GO:0010172 49 0.042
cellular macromolecule biosynthetic process GO:0034645 247 0.042
regulation of cellular metabolic process GO:0031323 305 0.042
death GO:0016265 547 0.042
cellular localization GO:0051641 360 0.042
regulation of cell projection organization GO:0031344 38 0.041
cellular component movement GO:0006928 388 0.041
membrane organization GO:0061024 135 0.040
gene silencing by rna GO:0031047 143 0.040
neurological system process GO:0050877 53 0.040
cellular nitrogen compound biosynthetic process GO:0044271 192 0.040
macromolecular complex subunit organization GO:0043933 320 0.040
hermaphrodite genitalia development GO:0040035 734 0.039
purine containing compound metabolic process GO:0072521 95 0.039
actin filament based process GO:0030029 191 0.038
nucleic acid templated transcription GO:0097659 169 0.038
aromatic compound biosynthetic process GO:0019438 192 0.038
positive regulation of rna biosynthetic process GO:1902680 102 0.038
cell migration GO:0016477 306 0.038
rna metabolic process GO:0016070 228 0.037
calcium mediated signaling GO:0019722 3 0.037
cellular component biogenesis GO:0044085 297 0.037
transmembrane transport GO:0055085 110 0.037
female gamete generation GO:0007292 254 0.036
myosin filament organization GO:0031033 138 0.036
small molecule metabolic process GO:0044281 186 0.036
post embryonic organ development GO:0048569 336 0.036
molting cycle GO:0042303 281 0.035
ion transmembrane transport GO:0034220 91 0.035
cellular protein metabolic process GO:0044267 279 0.035
cyclic nucleotide metabolic process GO:0009187 2 0.035
striated muscle cell differentiation GO:0051146 158 0.035
regulation of biosynthetic process GO:0009889 189 0.035
regulation of rna metabolic process GO:0051252 173 0.035
macromolecule modification GO:0043412 218 0.034
negative regulation of macromolecule metabolic process GO:0010605 229 0.034
protein complex biogenesis GO:0070271 186 0.034
purine ribonucleotide metabolic process GO:0009150 95 0.034
neuroblast fate determination GO:0007400 1 0.033
ion transport GO:0006811 113 0.033
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.033
regulation of nucleic acid templated transcription GO:1903506 165 0.032
striated muscle myosin thick filament assembly GO:0071688 138 0.032
organic substance catabolic process GO:1901575 294 0.031
cellular protein modification process GO:0006464 207 0.031
negative regulation of transporter activity GO:0032410 3 0.031
positive regulation of growth GO:0045927 369 0.030
vulval development GO:0040025 333 0.030
transcription from rna polymerase ii promoter GO:0006366 149 0.030
posttranscriptional regulation of gene expression GO:0010608 166 0.030
response to endogenous stimulus GO:0009719 33 0.030
protein complex assembly GO:0006461 186 0.030
response to abiotic stimulus GO:0009628 152 0.030
transcription dna templated GO:0006351 168 0.029
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.029
inactivation of mapkkk activity GO:0051390 2 0.029
protein localization GO:0008104 205 0.029
defecation rhythm GO:0035882 3 0.029
macromolecule catabolic process GO:0009057 202 0.029
inductive cell migration GO:0040039 145 0.028
regulation of cation channel activity GO:2001257 3 0.028
carbohydrate derivative metabolic process GO:1901135 141 0.028
muscle cell differentiation GO:0042692 171 0.028
negative regulation of signal transduction GO:0009968 60 0.028
catabolic process GO:0009056 318 0.028
positive regulation of macromolecule metabolic process GO:0010604 149 0.027
oocyte differentiation GO:0009994 45 0.027
negative regulation of ion transmembrane transport GO:0034766 3 0.027
phosphorylation GO:0016310 116 0.027
cilium assembly GO:0042384 28 0.026
positive regulation of cell communication GO:0010647 69 0.026
membrane invagination GO:0010324 98 0.026
epithelial cell proliferation GO:0050673 1 0.026
myosin filament assembly GO:0031034 138 0.026
regulation of nematode larval development GO:0061062 260 0.025
head development GO:0060322 1 0.025
secretion GO:0046903 147 0.025
protein modification process GO:0036211 207 0.024
negative regulation of response to stimulus GO:0048585 73 0.024
positive regulation of cellular metabolic process GO:0031325 178 0.023
regulation of neuromuscular synaptic transmission GO:1900073 1 0.023
mechanosensory behavior GO:0007638 25 0.023
negative regulation of ion transmembrane transporter activity GO:0032413 3 0.023
regulation of post embryonic development GO:0048580 260 0.023
negative regulation of cellular process GO:0048523 239 0.023
cellular response to hormone stimulus GO:0032870 14 0.022
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 16 0.022
positive regulation of transcription dna templated GO:0045893 102 0.022
mating behavior GO:0007617 32 0.022
cellular response to growth factor stimulus GO:0071363 18 0.022
pattern specification process GO:0007389 59 0.022
regulation of rna biosynthetic process GO:2001141 165 0.021
phagocytosis GO:0006909 115 0.021
macromolecular complex assembly GO:0065003 193 0.021
skeletal muscle organ development GO:0060538 3 0.021
cell division GO:0051301 262 0.020
positive regulation of cellular biosynthetic process GO:0031328 109 0.020
cell projection assembly GO:0030031 35 0.020
regulation of nitrogen compound metabolic process GO:0051171 222 0.020
negative regulation of metabolic process GO:0009892 240 0.020
posttranscriptional gene silencing GO:0016441 143 0.020
negative regulation of gene expression GO:0010629 217 0.020
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.019
regulation of epithelial cell proliferation GO:0050678 1 0.019
collagen and cuticulin based cuticle development GO:0040002 99 0.019
regulation of catalytic activity GO:0050790 78 0.019
organophosphate metabolic process GO:0019637 125 0.019
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.019
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 6 0.019
apoptotic cell clearance GO:0043277 111 0.019
intracellular signal transduction GO:0035556 96 0.019
regulation of cell proliferation GO:0042127 105 0.019
energy taxis GO:0009453 3 0.019
positive regulation of gene expression GO:0010628 112 0.019
rna biosynthetic process GO:0032774 169 0.019
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 34 0.019
insulin receptor signaling pathway GO:0008286 14 0.018
phagocytosis engulfment GO:0006911 98 0.018
regulation of cellular biosynthetic process GO:0031326 189 0.018
negative regulation of transmembrane transport GO:0034763 3 0.018
cognition GO:0050890 27 0.018
negative regulation of cell communication GO:0010648 61 0.018
protein phosphorylation GO:0006468 85 0.018
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 12 0.018
positive regulation of rna metabolic process GO:0051254 103 0.018
epithelial tube morphogenesis GO:0060562 1 0.017
learning or memory GO:0007611 27 0.017
engulfment of apoptotic cell GO:0043652 94 0.017
oocyte development GO:0048599 44 0.017
regulation of cellular protein metabolic process GO:0032268 75 0.017
organonitrogen compound metabolic process GO:1901564 151 0.017
negative regulation of post embryonic development GO:0048581 208 0.017
cellular response to abiotic stimulus GO:0071214 4 0.017
cell cell signaling GO:0007267 118 0.017
intraciliary transport GO:0042073 12 0.017
single organism biosynthetic process GO:0044711 91 0.017
muscle organ morphogenesis GO:0048644 4 0.016
protein catabolic process GO:0030163 162 0.016
cell proliferation GO:0008283 116 0.016
localization of cell GO:0051674 313 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.016
organonitrogen compound biosynthetic process GO:1901566 44 0.016
regulation of vulval development GO:0040028 248 0.016
nucleoside phosphate metabolic process GO:0006753 108 0.016
regulation of localization GO:0032879 194 0.016
regulation of cell division GO:0051302 142 0.016
regulation of nuclear division GO:0051783 115 0.016
negative regulation of cellular metabolic process GO:0031324 95 0.016
regulation of phosphorus metabolic process GO:0051174 81 0.016
regulation of molecular function GO:0065009 89 0.016
tube development GO:0035295 126 0.016
male mating behavior GO:0060179 26 0.016
intercellular transport GO:0010496 1 0.015
neuroblast fate commitment GO:0014017 5 0.015
protein complex subunit organization GO:0071822 280 0.015
regulation of defecation rhythm GO:2000746 3 0.015
microtubule based process GO:0007017 182 0.015
muscle tissue development GO:0060537 1 0.015
olfactory learning GO:0008355 17 0.015
positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 3 0.015
single organism cellular localization GO:1902580 72 0.015
cuticle development GO:0042335 100 0.015
regulation of insulin receptor signaling pathway GO:0046626 6 0.015
cell cycle process GO:0022402 482 0.015
eating behavior GO:0042755 59 0.015
microtubule based movement GO:0007018 33 0.015
feeding behavior GO:0007631 70 0.015
cilium organization GO:0044782 32 0.015
regulation of transport GO:0051049 91 0.014
organelle fission GO:0048285 363 0.014
response to temperature stimulus GO:0009266 66 0.014
adult behavior GO:0030534 3 0.014
positive regulation of response to stimulus GO:0048584 55 0.014
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.014
ribose phosphate metabolic process GO:0019693 99 0.014
positive regulation of neurogenesis GO:0050769 4 0.014
male anatomical structure morphogenesis GO:0090598 78 0.014
excretion GO:0007588 49 0.014
positive regulation of nucleic acid templated transcription GO:1903508 102 0.014
secretion by cell GO:0032940 138 0.014
rna interference GO:0016246 137 0.013
regulation of organelle organization GO:0033043 164 0.013
synaptic transmission GO:0007268 106 0.013
regulation of protein metabolic process GO:0051246 81 0.013
sensory perception of chemical stimulus GO:0007606 15 0.013
fertilization GO:0009566 63 0.013
negative regulation of nematode larval development GO:0061064 208 0.013
response to wounding GO:0009611 4 0.013
regulation of reproductive process GO:2000241 66 0.013
nucleotide metabolic process GO:0009117 108 0.013
meiotic nuclear division GO:0007126 300 0.013
gene silencing GO:0016458 143 0.013
organic acid metabolic process GO:0006082 47 0.013
carboxylic acid metabolic process GO:0019752 34 0.012
regulation of transcription dna templated GO:0006355 164 0.012
synaptic growth at neuromuscular junction GO:0051124 1 0.012
cellular ketone metabolic process GO:0042180 14 0.012
ribosome biogenesis GO:0042254 4 0.012
regulation of intracellular signal transduction GO:1902531 77 0.012
regulation of response to wounding GO:1903034 1 0.012
thermosensory behavior GO:0040040 9 0.012
regulation of meiotic cell cycle GO:0051445 136 0.012
digestive system development GO:0055123 122 0.012
positive regulation of signaling GO:0023056 66 0.012
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 5 0.012
regulation of cellular ketone metabolic process GO:0010565 3 0.012
cell cycle GO:0007049 526 0.012
neuron recognition GO:0008038 83 0.012
neuromuscular junction development GO:0007528 2 0.012
rna localization GO:0006403 3 0.012
organic substance transport GO:0071702 113 0.011
axonal fasciculation GO:0007413 79 0.011
regulation of cellular response to growth factor stimulus GO:0090287 11 0.011
positive regulation of cell projection organization GO:0031346 4 0.011
intracellular transport GO:0046907 77 0.011
regeneration GO:0031099 4 0.011
regulation of synaptic transmission GO:0050804 34 0.011
hatching GO:0035188 48 0.011
regulation of apoptotic signaling pathway GO:2001233 1 0.011
asymmetric protein localization GO:0008105 35 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
positive regulation of biosynthetic process GO:0009891 109 0.011
regulation of cytoplasmic transport GO:1903649 3 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.011
regulation of cellular amine metabolic process GO:0033238 0 0.011
cell recognition GO:0008037 85 0.011
positive regulation of protein transport GO:0051222 4 0.011
cell type specific apoptotic process GO:0097285 4 0.011
regulation of multi organism process GO:0043900 69 0.011
regulation of macromolecule biosynthetic process GO:0010556 189 0.011
organism emergence from protective structure GO:0071684 48 0.011
carbohydrate derivative biosynthetic process GO:1901137 46 0.010
negative regulation of neurogenesis GO:0050768 4 0.010
establishment of protein localization GO:0045184 50 0.010
learning GO:0007612 21 0.010
canonical wnt signaling pathway GO:0060070 3 0.010
response to peptide hormone GO:0043434 14 0.010
sensory perception of smell GO:0007608 3 0.010
ribonucleoprotein complex assembly GO:0022618 4 0.010
purine nucleotide metabolic process GO:0006163 95 0.010

che-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.011