Caenorhabditis elegans

16 known processes

lars-1 (CELE_R74.1)

Protein LARS-1

lars-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.860
post embryonic development GO:0009791 2152 0.592
embryo development GO:0009790 3052 0.449
receptor mediated endocytosis GO:0006898 715 0.297
macromolecule biosynthetic process GO:0009059 250 0.237
transport GO:0006810 1093 0.217
catabolic process GO:0009056 318 0.186
regulation of cellular biosynthetic process GO:0031326 189 0.181
gene expression GO:0010467 412 0.177
establishment of localization GO:0051234 1171 0.175
multicellular organism reproduction GO:0032504 819 0.172
negative regulation of biological process GO:0048519 567 0.168
death GO:0016265 547 0.166
genitalia development GO:0048806 741 0.166
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.165
sexual reproduction GO:0019953 546 0.164
locomotion GO:0040011 1634 0.156
regulation of nitrogen compound metabolic process GO:0051171 222 0.155
biosynthetic process GO:0009058 323 0.155
cellular macromolecule biosynthetic process GO:0034645 247 0.154
regulation of biological quality GO:0065008 741 0.142
organ development GO:0048513 1102 0.134
endocytosis GO:0006897 819 0.133
organelle organization GO:0006996 783 0.132
oviposition GO:0018991 364 0.124
organic substance biosynthetic process GO:1901576 323 0.124
regulation of biosynthetic process GO:0009889 189 0.123
regulation of primary metabolic process GO:0080090 292 0.123
ribonucleoprotein complex assembly GO:0022618 4 0.122
protein metabolic process GO:0019538 422 0.120
single organism localization GO:1902578 518 0.117
multicellular organismal reproductive behavior GO:0033057 384 0.117
multicellular organismal reproductive process GO:0048609 815 0.115
cell death GO:0008219 547 0.115
rna metabolic process GO:0016070 228 0.112
regulation of macromolecule metabolic process GO:0060255 421 0.111
regulation of cellular protein metabolic process GO:0032268 75 0.101
regulation of cellular component organization GO:0051128 248 0.100
negative regulation of post embryonic development GO:0048581 208 0.095
regulation of macromolecule biosynthetic process GO:0010556 189 0.093
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.093
meiotic nuclear division GO:0007126 300 0.090
posttranscriptional regulation of gene expression GO:0010608 166 0.089
negative regulation of macromolecule metabolic process GO:0010605 229 0.088
vesicle mediated transport GO:0016192 852 0.087
cellular protein metabolic process GO:0044267 279 0.086
negative regulation of metabolic process GO:0009892 240 0.085
regulation of cellular metabolic process GO:0031323 305 0.083
organic substance catabolic process GO:1901575 294 0.083
gonad development GO:0008406 840 0.082
reproductive structure development GO:0048608 850 0.082
multicellular organismal aging GO:0010259 812 0.080
organelle localization GO:0051640 127 0.079
signal transduction GO:0007165 317 0.078
regulation of metabolic process GO:0019222 478 0.078
single organism transport GO:0044765 447 0.078
cellular protein modification process GO:0006464 207 0.077
regulation of vulval development GO:0040028 248 0.077
body morphogenesis GO:0010171 620 0.076
programmed cell death GO:0012501 500 0.076
regulation of gene expression GO:0010468 366 0.074
sex differentiation GO:0007548 909 0.074
vulval development GO:0040025 333 0.074
rna localization GO:0006403 3 0.073
determination of adult lifespan GO:0008340 812 0.072
multi organism reproductive process GO:0044703 867 0.072
gamete generation GO:0007276 461 0.072
hermaphrodite genitalia development GO:0040035 734 0.071
macromolecule localization GO:0033036 771 0.071
cellular localization GO:0051641 360 0.070
cellular catabolic process GO:0044248 199 0.070
regulation of multicellular organismal process GO:0051239 726 0.068
response to chemical GO:0042221 356 0.068
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.068
nucleic acid metabolic process GO:0090304 299 0.067
regulation of developmental process GO:0050793 684 0.067
behavior GO:0007610 527 0.067
lipid storage GO:0019915 565 0.066
maintenance of location GO:0051235 580 0.065
reproductive behavior GO:0019098 387 0.065
developmental process involved in reproduction GO:0003006 1165 0.065
aging GO:0007568 812 0.063
single organism signaling GO:0044700 401 0.063
cellular component morphogenesis GO:0032989 318 0.063
cellular protein complex assembly GO:0043623 178 0.063
aromatic compound biosynthetic process GO:0019438 192 0.062
single organism organelle organization GO:1902589 501 0.062
developmental growth GO:0048589 412 0.062
negative regulation of cellular process GO:0048523 239 0.060
regulation of organelle organization GO:0033043 164 0.059
small molecule metabolic process GO:0044281 186 0.059
reproductive system development GO:0061458 850 0.059
regulation of rna biosynthetic process GO:2001141 165 0.058
establishment of organelle localization GO:0051656 123 0.057
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.055
multi organism reproductive behavior GO:0044705 387 0.055
intracellular transport GO:0046907 77 0.054
protein modification process GO:0036211 207 0.054
muscle tissue development GO:0060537 1 0.052
multi organism behavior GO:0051705 389 0.051
cellular biosynthetic process GO:0044249 315 0.051
female gamete generation GO:0007292 254 0.051
meiotic cell cycle GO:0051321 335 0.050
lipid localization GO:0010876 573 0.050
cellular component assembly GO:0022607 293 0.050
heterocycle catabolic process GO:0046700 119 0.050
signaling GO:0023052 401 0.050
regulation of post embryonic development GO:0048580 260 0.050
apoptotic process GO:0006915 478 0.048
positive regulation of cellular process GO:0048522 332 0.048
regulation of response to stimulus GO:0048583 243 0.048
transcription dna templated GO:0006351 168 0.048
translational initiation GO:0006413 2 0.048
localization of cell GO:0051674 313 0.047
single organism reproductive process GO:0044702 1196 0.047
oxoacid metabolic process GO:0043436 47 0.047
innate immune response GO:0045087 190 0.047
organic cyclic compound catabolic process GO:1901361 119 0.046
cell cycle GO:0007049 526 0.046
establishment of localization in cell GO:0051649 318 0.045
cellular component biogenesis GO:0044085 297 0.045
cytoskeleton organization GO:0007010 339 0.045
multicellular organism growth GO:0035264 385 0.045
regulation of multicellular organism growth GO:0040014 373 0.044
cell development GO:0048468 696 0.044
organelle fission GO:0048285 363 0.044
positive regulation of multicellular organism growth GO:0040018 352 0.044
regulation of protein metabolic process GO:0051246 81 0.044
positive regulation of multicellular organismal process GO:0051240 417 0.044
cellular macromolecular complex assembly GO:0034622 184 0.043
glycosyl compound catabolic process GO:1901658 79 0.043
mitotic cell cycle process GO:1903047 194 0.043
organic cyclic compound biosynthetic process GO:1901362 195 0.043
negative regulation of vulval development GO:0040027 206 0.042
cell division GO:0051301 262 0.041
purine ribonucleotide metabolic process GO:0009150 95 0.041
regulation of nucleic acid templated transcription GO:1903506 165 0.041
nucleobase containing compound metabolic process GO:0006139 406 0.040
negative regulation of gene expression GO:0010629 217 0.040
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.040
multi multicellular organism process GO:0044706 390 0.040
aromatic compound catabolic process GO:0019439 116 0.039
skeletal muscle organ development GO:0060538 3 0.039
development of primary sexual characteristics GO:0045137 840 0.039
molting cycle GO:0042303 281 0.039
positive regulation of developmental growth GO:0048639 354 0.039
cellular component movement GO:0006928 388 0.038
purine ribonucleoside catabolic process GO:0046130 75 0.038
cellular nitrogen compound catabolic process GO:0044270 119 0.038
macromolecular complex subunit organization GO:0043933 320 0.038
mitotic nuclear division GO:0007067 89 0.037
regulation of developmental growth GO:0048638 389 0.037
macromolecular complex assembly GO:0065003 193 0.036
positive regulation of growth GO:0045927 369 0.036
cellular response to organic substance GO:0071310 119 0.036
nucleobase containing compound catabolic process GO:0034655 114 0.035
ribonucleoside triphosphate catabolic process GO:0009203 72 0.035
cell motility GO:0048870 313 0.035
anatomical structure formation involved in morphogenesis GO:0048646 250 0.035
positive regulation of rna biosynthetic process GO:1902680 102 0.035
post embryonic organ development GO:0048569 336 0.034
regulation of signaling GO:0023051 172 0.034
regulation of cell division GO:0051302 142 0.034
positive regulation of metabolic process GO:0009893 187 0.034
purine nucleotide catabolic process GO:0006195 75 0.033
rna biosynthetic process GO:0032774 169 0.033
negative regulation of nematode larval development GO:0061064 208 0.033
nucleoside triphosphate catabolic process GO:0009143 72 0.033
negative regulation of protein metabolic process GO:0051248 27 0.032
negative regulation of cellular protein metabolic process GO:0032269 27 0.032
actin filament based process GO:0030029 191 0.032
organelle assembly GO:0070925 214 0.032
regulation of nematode larval development GO:0061062 260 0.031
macromolecule catabolic process GO:0009057 202 0.031
germ cell development GO:0007281 351 0.031
positive regulation of biosynthetic process GO:0009891 109 0.031
growth GO:0040007 562 0.031
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.031
regulation of nuclear division GO:0051783 115 0.031
positive regulation of cellular metabolic process GO:0031325 178 0.031
nucleic acid templated transcription GO:0097659 169 0.031
nucleoside triphosphate metabolic process GO:0009141 87 0.031
organonitrogen compound metabolic process GO:1901564 151 0.030
regulation of translation GO:0006417 19 0.030
translation GO:0006412 37 0.030
intracellular signal transduction GO:0035556 96 0.030
ribonucleoside catabolic process GO:0042454 77 0.030
regulation of meiotic cell cycle GO:0051445 136 0.030
positive regulation of nucleic acid templated transcription GO:1903508 102 0.030
positive regulation of rna metabolic process GO:0051254 103 0.030
oogenesis GO:0048477 229 0.030
nucleoside phosphate catabolic process GO:1901292 77 0.029
oocyte differentiation GO:0009994 45 0.029
ribonucleotide catabolic process GO:0009261 75 0.029
protein complex subunit organization GO:0071822 280 0.029
nucleotide catabolic process GO:0009166 77 0.029
negative regulation of cellular metabolic process GO:0031324 95 0.029
gene silencing by rna GO:0031047 143 0.029
positive regulation of gene expression GO:0010628 112 0.029
single organism catabolic process GO:0044712 129 0.028
epithelial tube morphogenesis GO:0060562 1 0.028
carbohydrate derivative catabolic process GO:1901136 82 0.028
modification dependent protein catabolic process GO:0019941 32 0.028
positive regulation of developmental process GO:0051094 408 0.028
regulation of growth GO:0040008 409 0.028
purine nucleoside triphosphate metabolic process GO:0009144 87 0.028
regulation of molecular function GO:0065009 89 0.028
nucleoside catabolic process GO:0009164 78 0.027
regulation of signal transduction GO:0009966 135 0.027
macromolecule modification GO:0043412 218 0.027
muscle cell development GO:0055001 158 0.026
protein polymerization GO:0051258 26 0.026
cellular response to chemical stimulus GO:0070887 129 0.026
purine nucleoside catabolic process GO:0006152 75 0.026
tissue development GO:0009888 112 0.026
chromatin assembly or disassembly GO:0006333 1 0.026
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.026
cell cycle process GO:0022402 482 0.025
dna metabolic process GO:0006259 74 0.025
positive regulation of transcription dna templated GO:0045893 102 0.025
sensory organ morphogenesis GO:0090596 2 0.025
neurogenesis GO:0022008 236 0.025
cellular component assembly involved in morphogenesis GO:0010927 183 0.024
organic acid metabolic process GO:0006082 47 0.024
regulation of localization GO:0032879 194 0.024
ribonucleoside metabolic process GO:0009119 98 0.024
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.024
organophosphate metabolic process GO:0019637 125 0.024
negative regulation of biosynthetic process GO:0009890 65 0.024
organophosphate catabolic process GO:0046434 81 0.024
negative regulation of multicellular organismal process GO:0051241 236 0.024
oocyte development GO:0048599 44 0.024
ribose phosphate metabolic process GO:0019693 99 0.023
ribosome biogenesis GO:0042254 4 0.023
negative regulation of developmental process GO:0051093 227 0.023
carbohydrate derivative metabolic process GO:1901135 141 0.023
actin cytoskeleton organization GO:0030036 184 0.023
posttranscriptional gene silencing by rna GO:0035194 143 0.022
glycosyl compound metabolic process GO:1901657 100 0.022
regulation of apoptotic signaling pathway GO:2001233 1 0.022
purine nucleoside triphosphate catabolic process GO:0009146 72 0.022
positive regulation of cellular biosynthetic process GO:0031328 109 0.022
spindle localization GO:0051653 51 0.022
nucleotide metabolic process GO:0009117 108 0.022
regulation of transcription dna templated GO:0006355 164 0.022
cell part morphogenesis GO:0032990 152 0.021
regulation of meiosis GO:0040020 94 0.021
regulation of gene expression epigenetic GO:0040029 163 0.021
heterocycle biosynthetic process GO:0018130 187 0.021
striated muscle myosin thick filament assembly GO:0071688 138 0.021
membrane organization GO:0061024 135 0.020
striated muscle cell development GO:0055002 157 0.020
regulation of rna metabolic process GO:0051252 173 0.020
establishment of spindle localization GO:0051293 51 0.020
cellular nitrogen compound biosynthetic process GO:0044271 192 0.020
phosphorus metabolic process GO:0006793 232 0.020
cellular amino acid metabolic process GO:0006520 15 0.020
cell migration GO:0016477 306 0.020
defense response GO:0006952 296 0.020
cellular response to stress GO:0033554 162 0.020
oocyte construction GO:0007308 2 0.020
purine containing compound catabolic process GO:0072523 75 0.020
regulation of cell cycle process GO:0010564 145 0.019
ribonucleoside triphosphate metabolic process GO:0009199 87 0.019
striated muscle cell differentiation GO:0051146 158 0.019
nucleobase containing small molecule metabolic process GO:0055086 115 0.019
positive regulation of macromolecule metabolic process GO:0010604 149 0.019
guanosine containing compound metabolic process GO:1901068 49 0.019
cell morphogenesis GO:0000902 163 0.019
protein catabolic process GO:0030163 162 0.019
protein localization GO:0008104 205 0.019
system process GO:0003008 136 0.019
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.019
purine nucleotide metabolic process GO:0006163 95 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.018
regulation of cell communication GO:0010646 176 0.018
negative regulation of signaling GO:0023057 61 0.018
negative regulation of translation GO:0017148 10 0.018
microtubule based process GO:0007017 182 0.017
regulation of phosphorus metabolic process GO:0051174 81 0.017
phagocytosis GO:0006909 115 0.017
regulation of cell proliferation GO:0042127 105 0.017
neuromuscular junction development GO:0007528 2 0.017
carboxylic acid metabolic process GO:0019752 34 0.017
myosin filament assembly GO:0031034 138 0.017
phosphate containing compound metabolic process GO:0006796 232 0.017
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.017
transcription from rna polymerase ii promoter GO:0006366 149 0.017
pattern specification process GO:0007389 59 0.017
fertilization GO:0009566 63 0.016
rna interference GO:0016246 137 0.016
nervous system development GO:0007399 253 0.016
cell morphogenesis involved in differentiation GO:0000904 112 0.016
meiotic cell cycle process GO:1903046 170 0.016
guanosine containing compound catabolic process GO:1901069 48 0.016
nucleoside metabolic process GO:0009116 99 0.016
negative regulation of cellular biosynthetic process GO:0031327 65 0.016
purine nucleoside metabolic process GO:0042278 92 0.016
cellular macromolecule catabolic process GO:0044265 73 0.016
posttranscriptional gene silencing GO:0016441 143 0.016
homeostatic process GO:0042592 51 0.016
myofibril assembly GO:0030239 154 0.015
rna processing GO:0006396 34 0.015
regulation of cellular ketone metabolic process GO:0010565 3 0.015
collagen and cuticulin based cuticle development GO:0040002 99 0.015
response to external stimulus GO:0009605 289 0.015
protein complex assembly GO:0006461 186 0.015
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.015
muscle fiber development GO:0048747 2 0.015
myosin filament organization GO:0031033 138 0.015
actomyosin structure organization GO:0031032 154 0.015
regulation of cell cycle GO:0051726 194 0.015
neuron projection morphogenesis GO:0048812 114 0.015
nucleobase containing compound biosynthetic process GO:0034654 184 0.015
small gtpase mediated signal transduction GO:0007264 32 0.015
regulation of cell differentiation GO:0045595 81 0.014
protein complex biogenesis GO:0070271 186 0.014
negative regulation of response to stimulus GO:0048585 73 0.014
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.014
negative regulation of signal transduction GO:0009968 60 0.014
negative regulation of cell communication GO:0010648 61 0.014
cell projection morphogenesis GO:0048858 148 0.014
regulation of reproductive process GO:2000241 66 0.013
single organism intracellular transport GO:1902582 70 0.013
negative regulation of locomotion GO:0040013 21 0.013
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.013
lipid metabolic process GO:0006629 77 0.013
single organism biosynthetic process GO:0044711 91 0.013
adult behavior GO:0030534 3 0.013
ribonucleotide metabolic process GO:0009259 99 0.013
oocyte axis specification GO:0007309 2 0.013
cellular response to abiotic stimulus GO:0071214 4 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.012
rrna processing GO:0006364 3 0.012
neuron development GO:0048666 199 0.012
dna templated transcription initiation GO:0006352 3 0.012
head development GO:0060322 1 0.012
cellular amine metabolic process GO:0044106 15 0.012
protein modification by small protein conjugation or removal GO:0070647 40 0.012
oxidation reduction process GO:0055114 59 0.012
organic substance transport GO:0071702 113 0.012
response to wounding GO:0009611 4 0.012
organonitrogen compound catabolic process GO:1901565 90 0.012
regulation of behavior GO:0050795 97 0.012
p38mapk cascade GO:0038066 2 0.012
regulation of striated muscle contraction GO:0006942 4 0.011
establishment of mitotic spindle localization GO:0040001 41 0.011
chromatin remodeling GO:0006338 2 0.011
purine containing compound metabolic process GO:0072521 95 0.011
peptidyl amino acid modification GO:0018193 58 0.011
nucleoside phosphate metabolic process GO:0006753 108 0.011
sister chromatid segregation GO:0000819 46 0.011
neuron projection guidance GO:0097485 82 0.011
regulation of protein ubiquitination GO:0031396 3 0.011
purine ribonucleotide catabolic process GO:0009154 75 0.011
regulation of cellular component biogenesis GO:0044087 26 0.011
pole plasm assembly GO:0007315 2 0.010
proteolysis GO:0006508 61 0.010
tube development GO:0035295 126 0.010
protein phosphorylation GO:0006468 85 0.010
cell surface receptor signaling pathway GO:0007166 149 0.010
protein oligomerization GO:0051259 4 0.010
chromosome segregation GO:0007059 180 0.010
cell type specific apoptotic process GO:0097285 4 0.010
regulation of cellular amine metabolic process GO:0033238 0 0.010

lars-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018
immune system disease DOID:2914 0 0.017
hematopoietic system disease DOID:74 0 0.017
congenital hypoplastic anemia DOID:1342 0 0.012
diamond blackfan anemia DOID:1339 0 0.012
aplastic anemia DOID:12449 0 0.012
bone marrow disease DOID:4961 0 0.012
anemia DOID:2355 0 0.012
nervous system disease DOID:863 0 0.011