Caenorhabditis elegans

125 known processes

unc-78 (CELE_C04F6.4)

Protein UNC-78

unc-78 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.470
organelle organization GO:0006996 783 0.410
single organism reproductive process GO:0044702 1196 0.389
development of primary sexual characteristics GO:0045137 840 0.380
multicellular organismal reproductive process GO:0048609 815 0.368
death GO:0016265 547 0.359
reproductive structure development GO:0048608 850 0.359
establishment of localization GO:0051234 1171 0.350
developmental process involved in reproduction GO:0003006 1165 0.316
transport GO:0006810 1093 0.308
sexual reproduction GO:0019953 546 0.302
cell death GO:0008219 547 0.294
genitalia development GO:0048806 741 0.286
post embryonic development GO:0009791 2152 0.278
cellular response to unfolded protein GO:0034620 71 0.273
programmed cell death GO:0012501 500 0.270
multicellular organism reproduction GO:0032504 819 0.253
multi organism reproductive process GO:0044703 867 0.251
gonad development GO:0008406 840 0.240
hermaphrodite genitalia development GO:0040035 734 0.226
locomotion GO:0040011 1634 0.218
organelle assembly GO:0070925 214 0.208
single organism signaling GO:0044700 401 0.200
embryo development ending in birth or egg hatching GO:0009792 2992 0.198
response to abiotic stimulus GO:0009628 152 0.194
gamete generation GO:0007276 461 0.194
germ cell development GO:0007281 351 0.191
meiotic nuclear division GO:0007126 300 0.188
cell development GO:0048468 696 0.185
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.184
positive regulation of cellular process GO:0048522 332 0.180
protein localization GO:0008104 205 0.174
organic substance catabolic process GO:1901575 294 0.158
female gamete generation GO:0007292 254 0.155
organ development GO:0048513 1102 0.154
apoptotic process GO:0006915 478 0.152
oogenesis GO:0048477 229 0.151
regulation of biological quality GO:0065008 741 0.146
regulation of developmental process GO:0050793 684 0.145
Rat
cell motility GO:0048870 313 0.138
vesicle mediated transport GO:0016192 852 0.137
response to chemical GO:0042221 356 0.136
cellular response to topologically incorrect protein GO:0035967 76 0.126
protein metabolic process GO:0019538 422 0.122
regulation of cellular component organization GO:0051128 248 0.118
single organism localization GO:1902578 518 0.117
macromolecule catabolic process GO:0009057 202 0.115
ion transport GO:0006811 113 0.112
single organism organelle organization GO:1902589 501 0.108
regulation of signaling GO:0023051 172 0.107
cell surface receptor signaling pathway GO:0007166 149 0.103
growth GO:0040007 562 0.102
macromolecule localization GO:0033036 771 0.099
phosphate containing compound metabolic process GO:0006796 232 0.097
receptor mediated endocytosis GO:0006898 715 0.096
phosphorus metabolic process GO:0006793 232 0.096
muscle structure development GO:0061061 191 0.094
cellular component movement GO:0006928 388 0.090
determination of adult lifespan GO:0008340 812 0.088
lipid localization GO:0010876 573 0.086
signaling GO:0023052 401 0.086
single organism transport GO:0044765 447 0.085
lipid storage GO:0019915 565 0.085
regulation of response to stimulus GO:0048583 243 0.084
oocyte differentiation GO:0009994 45 0.082
response to organic substance GO:0010033 131 0.082
catabolic process GO:0009056 318 0.082
positive regulation of growth GO:0045927 369 0.081
endocytosis GO:0006897 819 0.077
regulation of growth GO:0040008 409 0.076
aging GO:0007568 812 0.076
protein modification process GO:0036211 207 0.076
meiotic cell cycle GO:0051321 335 0.075
organic cyclic compound biosynthetic process GO:1901362 195 0.075
sex differentiation GO:0007548 909 0.074
cell cycle process GO:0022402 482 0.074
reproductive system development GO:0061458 850 0.073
maintenance of location GO:0051235 580 0.072
signal transduction GO:0007165 317 0.070
cell migration GO:0016477 306 0.070
cellular protein metabolic process GO:0044267 279 0.069
endoplasmic reticulum unfolded protein response GO:0030968 66 0.068
regulation of macromolecule metabolic process GO:0060255 421 0.067
response to endoplasmic reticulum stress GO:0034976 71 0.066
striated muscle cell differentiation GO:0051146 158 0.066
regulation of cellular protein metabolic process GO:0032268 75 0.064
cellular biosynthetic process GO:0044249 315 0.062
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.062
localization of cell GO:0051674 313 0.062
positive regulation of developmental process GO:0051094 408 0.061
regulation of localization GO:0032879 194 0.060
muscle tissue development GO:0060537 1 0.060
muscle cell differentiation GO:0042692 171 0.059
multi organism behavior GO:0051705 389 0.058
regulation of metabolic process GO:0019222 478 0.058
multicellular organismal reproductive behavior GO:0033057 384 0.058
response to external stimulus GO:0009605 289 0.058
microvillus organization GO:0032528 1 0.057
organelle fission GO:0048285 363 0.056
sensory organ morphogenesis GO:0090596 2 0.055
developmental growth GO:0048589 412 0.055
regulation of cell motility GO:2000145 57 0.054
cellular response to chemical stimulus GO:0070887 129 0.054
positive regulation of multicellular organismal process GO:0051240 417 0.054
body morphogenesis GO:0010171 620 0.053
cellular localization GO:0051641 360 0.053
oxoacid metabolic process GO:0043436 47 0.051
regulation of cell communication GO:0010646 176 0.051
regulation of organelle organization GO:0033043 164 0.050
cell division GO:0051301 262 0.050
regulation of cell differentiation GO:0045595 81 0.049
Rat
cell cycle GO:0007049 526 0.049
striated muscle cell development GO:0055002 157 0.049
actin filament based process GO:0030029 191 0.049
protein catabolic process GO:0030163 162 0.048
gene expression GO:0010467 412 0.048
nucleobase containing compound metabolic process GO:0006139 406 0.047
regulation of multicellular organism growth GO:0040014 373 0.047
response to topologically incorrect protein GO:0035966 82 0.046
macromolecule modification GO:0043412 218 0.046
anatomical structure formation involved in morphogenesis GO:0048646 250 0.046
single fertilization GO:0007338 61 0.046
positive regulation of multicellular organism growth GO:0040018 352 0.045
nervous system development GO:0007399 253 0.045
Rat
multicellular organism growth GO:0035264 385 0.044
secretion GO:0046903 147 0.043
regulation of developmental growth GO:0048638 389 0.042
organonitrogen compound metabolic process GO:1901564 151 0.041
macromolecule biosynthetic process GO:0009059 250 0.041
small molecule metabolic process GO:0044281 186 0.041
establishment of mitotic spindle orientation GO:0000132 28 0.040
oocyte development GO:0048599 44 0.040
head development GO:0060322 1 0.040
behavior GO:0007610 527 0.039
positive regulation of developmental growth GO:0048639 354 0.039
cation transport GO:0006812 78 0.038
establishment of localization in cell GO:0051649 318 0.037
cellular protein complex assembly GO:0043623 178 0.037
regulation of multicellular organismal process GO:0051239 726 0.037
Rat
meiotic chromosome segregation GO:0045132 139 0.037
nucleoside phosphate catabolic process GO:1901292 77 0.036
multicellular organismal aging GO:0010259 812 0.036
reproductive behavior GO:0019098 387 0.035
negative regulation of vulval development GO:0040027 206 0.034
establishment of spindle localization GO:0051293 51 0.034
cellular component assembly GO:0022607 293 0.034
cellular component morphogenesis GO:0032989 318 0.034
cellular protein modification process GO:0006464 207 0.033
er nucleus signaling pathway GO:0006984 66 0.032
protein complex subunit organization GO:0071822 280 0.032
regulation of locomotion GO:0040012 161 0.032
regulation of gene expression GO:0010468 366 0.032
fertilization GO:0009566 63 0.032
cellular response to stress GO:0033554 162 0.031
regulation of signal transduction GO:0009966 135 0.031
myosin filament assembly GO:0031034 138 0.031
nucleus localization GO:0051647 55 0.031
organic substance biosynthetic process GO:1901576 323 0.030
positive regulation of macromolecule metabolic process GO:0010604 149 0.030
oviposition GO:0018991 364 0.029
regulation of cellular metabolic process GO:0031323 305 0.029
cellular protein localization GO:0034613 75 0.029
regulation of syncytium formation by plasma membrane fusion GO:0060142 4 0.028
taxis GO:0042330 128 0.028
regulation of cellular localization GO:0060341 42 0.028
neurological system process GO:0050877 53 0.028
defense response GO:0006952 296 0.028
organic substance transport GO:0071702 113 0.028
actin cytoskeleton organization GO:0030036 184 0.027
biosynthetic process GO:0009058 323 0.027
regulation of vulval development GO:0040028 248 0.027
response to wounding GO:0009611 4 0.026
inductive cell migration GO:0040039 145 0.026
intracellular transport GO:0046907 77 0.026
establishment of spindle orientation GO:0051294 34 0.026
negative regulation of nematode larval development GO:0061064 208 0.026
negative regulation of developmental process GO:0051093 227 0.026
phagocytosis GO:0006909 115 0.025
regulation of nematode larval development GO:0061062 260 0.025
regulation of cell division GO:0051302 142 0.025
microtubule based process GO:0007017 182 0.024
nucleic acid templated transcription GO:0097659 169 0.024
regulation of cell cycle GO:0051726 194 0.024
oocyte axis specification GO:0007309 2 0.024
negative regulation of post embryonic development GO:0048581 208 0.023
positive regulation of biosynthetic process GO:0009891 109 0.023
positive regulation of cell communication GO:0010647 69 0.023
spindle localization GO:0051653 51 0.023
single organism catabolic process GO:0044712 129 0.023
pronuclear migration GO:0035046 51 0.023
regulation of cell death GO:0010941 65 0.022
organic acid metabolic process GO:0006082 47 0.022
negative regulation of biological process GO:0048519 567 0.022
macromolecular complex subunit organization GO:0043933 320 0.022
negative regulation of cellular process GO:0048523 239 0.022
peptidyl amino acid modification GO:0018193 58 0.022
epithelial tube morphogenesis GO:0060562 1 0.022
tissue development GO:0009888 112 0.022
organelle localization GO:0051640 127 0.020
carbohydrate metabolic process GO:0005975 34 0.020
establishment of protein localization to membrane GO:0090150 3 0.020
mitotic nuclear division GO:0007067 89 0.020
regulation of multicellular organismal development GO:2000026 317 0.019
Rat
small molecule biosynthetic process GO:0044283 38 0.019
ribonucleoside triphosphate catabolic process GO:0009203 72 0.019
regulation of biosynthetic process GO:0009889 189 0.019
regulation of transport GO:0051049 91 0.019
cellular component biogenesis GO:0044085 297 0.019
positive regulation of metabolic process GO:0009893 187 0.019
regulation of cell migration GO:0030334 55 0.019
response to external biotic stimulus GO:0043207 101 0.019
oocyte construction GO:0007308 2 0.019
regulation of rna metabolic process GO:0051252 173 0.018
neurogenesis GO:0022008 236 0.018
Rat
chromosome segregation GO:0007059 180 0.018
transmembrane transport GO:0055085 110 0.018
cellular macromolecular complex assembly GO:0034622 184 0.018
ribonucleotide catabolic process GO:0009261 75 0.018
regulation of apoptotic signaling pathway GO:2001233 1 0.018
regulation of post embryonic development GO:0048580 260 0.018
signal transduction by phosphorylation GO:0023014 31 0.018
negative regulation of multicellular organismal process GO:0051241 236 0.018
nucleobase containing small molecule metabolic process GO:0055086 115 0.018
multi organism reproductive behavior GO:0044705 387 0.017
carboxylic acid metabolic process GO:0019752 34 0.017
establishment or maintenance of cell polarity GO:0007163 63 0.017
cellular catabolic process GO:0044248 199 0.017
establishment of mitotic spindle localization GO:0040001 41 0.017
aromatic compound biosynthetic process GO:0019438 192 0.017
macromolecular complex assembly GO:0065003 193 0.017
negative regulation of cellular component organization GO:0051129 33 0.017
mitotic cell cycle process GO:1903047 194 0.017
peptide cross linking GO:0018149 3 0.017
regulation of primary metabolic process GO:0080090 292 0.016
positive regulation of protein metabolic process GO:0051247 45 0.016
actomyosin structure organization GO:0031032 154 0.016
myofibril assembly GO:0030239 154 0.016
regulation of intracellular signal transduction GO:1902531 77 0.016
positive regulation of gene expression GO:0010628 112 0.016
secretion by cell GO:0032940 138 0.016
cytoskeleton organization GO:0007010 339 0.016
positive regulation of response to stimulus GO:0048584 55 0.016
negative regulation of transmembrane transport GO:0034763 3 0.016
cell projection organization GO:0030030 231 0.016
regulation of behavior GO:0050795 97 0.016
positive regulation of signaling GO:0023056 66 0.016
cellular component assembly involved in morphogenesis GO:0010927 183 0.016
purine nucleoside metabolic process GO:0042278 92 0.016
multi multicellular organism process GO:0044706 390 0.016
muscle cell development GO:0055001 158 0.015
cellular nitrogen compound biosynthetic process GO:0044271 192 0.015
memory GO:0007613 3 0.015
regulation of cellular biosynthetic process GO:0031326 189 0.015
protein phosphorylation GO:0006468 85 0.015
positive regulation of cellular biosynthetic process GO:0031328 109 0.015
cellular macromolecule localization GO:0070727 75 0.015
carbohydrate derivative metabolic process GO:1901135 141 0.015
cell substrate adhesion GO:0031589 1 0.015
response to temperature stimulus GO:0009266 66 0.015
establishment of cell polarity GO:0030010 46 0.015
response to osmotic stress GO:0006970 29 0.015
regulation of programmed cell death GO:0043067 50 0.015
chemotaxis GO:0006935 120 0.015
embryonic morphogenesis GO:0048598 152 0.015
intracellular signal transduction GO:0035556 96 0.015
endomembrane system organization GO:0010256 22 0.014
actin filament based movement GO:0030048 4 0.014
organic cyclic compound catabolic process GO:1901361 119 0.014
single organism behavior GO:0044708 83 0.014
myosin filament organization GO:0031033 138 0.014
divalent inorganic cation transport GO:0072511 17 0.014
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.014
regulation of rna biosynthetic process GO:2001141 165 0.014
striated muscle myosin thick filament assembly GO:0071688 138 0.014
microvillus assembly GO:0030033 1 0.014
single organism intracellular transport GO:1902582 70 0.014
positive regulation of programmed cell death GO:0043068 27 0.014
regulation of cellular component movement GO:0051270 62 0.014
response to nutrient levels GO:0031667 35 0.014
rna localization GO:0006403 3 0.014
transcription from rna polymerase ii promoter GO:0006366 149 0.014
rna biosynthetic process GO:0032774 169 0.013
nucleotide sugar metabolic process GO:0009225 6 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.013
nucleobase containing compound biosynthetic process GO:0034654 184 0.013
regulation of cell cycle process GO:0010564 145 0.013
organ morphogenesis GO:0009887 67 0.013
negative regulation of ion transmembrane transport GO:0034766 3 0.013
single organism biosynthetic process GO:0044711 91 0.013
negative regulation of macromolecule metabolic process GO:0010605 229 0.013
regulation of protein metabolic process GO:0051246 81 0.013
sister chromatid segregation GO:0000819 46 0.013
regulation of cellular ph GO:0030641 4 0.013
organophosphate metabolic process GO:0019637 125 0.013
nuclear migration GO:0007097 54 0.013
cell projection assembly GO:0030031 35 0.013
response to unfolded protein GO:0006986 71 0.013
regulation of nitrogen compound metabolic process GO:0051171 222 0.013
negative regulation of gene expression GO:0010629 217 0.012
rna interference GO:0016246 137 0.012
meiotic cell cycle process GO:1903046 170 0.012
cellular amino acid metabolic process GO:0006520 15 0.012
skeletal muscle organ development GO:0060538 3 0.012
immune response GO:0006955 192 0.012
female meiotic division GO:0007143 17 0.012
cuticle development GO:0042335 100 0.012
cilium morphogenesis GO:0060271 33 0.012
negative regulation of cell communication GO:0010648 61 0.012
cell proliferation GO:0008283 116 0.012
oxidation reduction process GO:0055114 59 0.012
rna metabolic process GO:0016070 228 0.012
single organism carbohydrate metabolic process GO:0044723 29 0.012
posttranscriptional gene silencing by rna GO:0035194 143 0.012
synaptic growth at neuromuscular junction GO:0051124 1 0.012
regulation of nucleic acid templated transcription GO:1903506 165 0.011
response to anesthetic GO:0072347 1 0.011
response to oxygen levels GO:0070482 22 0.011
regulation of cell morphogenesis GO:0022604 40 0.011
ion transmembrane transport GO:0034220 91 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.011
gene silencing by rna GO:0031047 143 0.011
aromatic compound catabolic process GO:0019439 116 0.011
purine ribonucleoside catabolic process GO:0046130 75 0.011
actin mediated cell contraction GO:0070252 3 0.011
glycosylation GO:0070085 20 0.011
regulation of protein targeting GO:1903533 3 0.011
positive regulation of cell death GO:0010942 38 0.011
g protein coupled receptor signaling pathway GO:0007186 46 0.011
metal ion transport GO:0030001 49 0.011
nucleobase containing compound catabolic process GO:0034655 114 0.011
heterocycle biosynthetic process GO:0018130 187 0.011
negative regulation of metabolic process GO:0009892 240 0.010
response to oxygen containing compound GO:1901700 44 0.010
glycosyl compound catabolic process GO:1901658 79 0.010
nucleic acid metabolic process GO:0090304 299 0.010
developmental maturation GO:0021700 26 0.010
molting cycle GO:0042303 281 0.010
epithelial cell proliferation GO:0050673 1 0.010
establishment of nucleus localization GO:0040023 55 0.010
protein glycosylation GO:0006486 17 0.010
regulation of phosphorus metabolic process GO:0051174 81 0.010
positive regulation of cell migration GO:0030335 3 0.010
regulation of nuclear division GO:0051783 115 0.010
cell matrix adhesion GO:0007160 1 0.010

unc-78 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.021
disease of cellular proliferation DOID:14566 0 0.021
disease of metabolism DOID:0014667 0 0.019
disease of anatomical entity DOID:7 0 0.017
inherited metabolic disorder DOID:655 0 0.012
organ system cancer DOID:0050686 0 0.011
gastrointestinal system cancer DOID:3119 0 0.011
myopathy DOID:423 0 0.010
muscular disease DOID:0080000 0 0.010
heart disease DOID:114 0 0.010
cardiomyopathy DOID:0050700 0 0.010
cardiovascular system disease DOID:1287 0 0.010
musculoskeletal system disease DOID:17 0 0.010
muscle tissue disease DOID:66 0 0.010