Caenorhabditis elegans

32 known processes

klp-18 (CELE_C06G3.2)

Protein KLP-18

klp-18 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.857
embryo development ending in birth or egg hatching GO:0009792 2992 0.857
meiotic cell cycle GO:0051321 335 0.839
organelle organization GO:0006996 783 0.813
meiotic chromosome segregation GO:0045132 139 0.776
meiotic nuclear division GO:0007126 300 0.660
germ cell development GO:0007281 351 0.598
gamete generation GO:0007276 461 0.504
cell cycle GO:0007049 526 0.489
multi organism reproductive process GO:0044703 867 0.466
multicellular organism reproduction GO:0032504 819 0.459
chromosome organization GO:0051276 104 0.453
regulation of meiotic cell cycle GO:0051445 136 0.426
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.405
multicellular organismal reproductive process GO:0048609 815 0.402
cell division GO:0051301 262 0.392
oogenesis GO:0048477 229 0.371
regulation of metabolic process GO:0019222 478 0.358
sexual reproduction GO:0019953 546 0.348
regulation of primary metabolic process GO:0080090 292 0.340
regulation of gene expression GO:0010468 366 0.325
meiotic cell cycle process GO:1903046 170 0.319
regulation of cell cycle process GO:0010564 145 0.318
single organism organelle organization GO:1902589 501 0.316
regulation of cellular biosynthetic process GO:0031326 189 0.284
regulation of nuclear division GO:0051783 115 0.277
regulation of organelle organization GO:0033043 164 0.275
transport GO:0006810 1093 0.241
regulation of cellular component organization GO:0051128 248 0.239
regulation of meiosis GO:0040020 94 0.234
cell cycle process GO:0022402 482 0.225
regulation of protein metabolic process GO:0051246 81 0.224
protein modification process GO:0036211 207 0.224
protein metabolic process GO:0019538 422 0.212
oocyte development GO:0048599 44 0.202
positive regulation of cellular process GO:0048522 332 0.200
positive regulation of biosynthetic process GO:0009891 109 0.197
mitotic nuclear division GO:0007067 89 0.193
protein complex subunit organization GO:0071822 280 0.190
regulation of cellular metabolic process GO:0031323 305 0.190
chromosome organization involved in meiosis GO:0070192 25 0.186
cell development GO:0048468 696 0.186
mitotic sister chromatid segregation GO:0000070 38 0.185
macromolecule modification GO:0043412 218 0.185
organelle fission GO:0048285 363 0.176
oocyte differentiation GO:0009994 45 0.175
actin filament based process GO:0030029 191 0.171
determination of adult lifespan GO:0008340 812 0.169
cellular component morphogenesis GO:0032989 318 0.162
post embryonic development GO:0009791 2152 0.156
macromolecular complex subunit organization GO:0043933 320 0.153
cellular protein metabolic process GO:0044267 279 0.145
protein complex biogenesis GO:0070271 186 0.137
negative regulation of cellular process GO:0048523 239 0.136
cellular protein modification process GO:0006464 207 0.134
regulation of biological quality GO:0065008 741 0.132
regulation of cell division GO:0051302 142 0.132
endocytosis GO:0006897 819 0.132
establishment of localization GO:0051234 1171 0.131
multicellular organismal reproductive behavior GO:0033057 384 0.128
positive regulation of gene expression GO:0010628 112 0.122
multi organism behavior GO:0051705 389 0.121
multicellular organismal aging GO:0010259 812 0.121
dna packaging GO:0006323 7 0.119
oviposition GO:0018991 364 0.118
mitotic cell cycle process GO:1903047 194 0.117
cellular biosynthetic process GO:0044249 315 0.112
locomotion GO:0040011 1634 0.110
single organism signaling GO:0044700 401 0.108
single organism reproductive process GO:0044702 1196 0.107
signal transduction GO:0007165 317 0.106
catabolic process GO:0009056 318 0.104
macromolecule localization GO:0033036 771 0.103
growth GO:0040007 562 0.103
female gamete generation GO:0007292 254 0.101
cellular component biogenesis GO:0044085 297 0.101
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.100
establishment of organelle localization GO:0051656 123 0.098
cytoskeleton organization GO:0007010 339 0.097
organonitrogen compound catabolic process GO:1901565 90 0.094
cell part morphogenesis GO:0032990 152 0.094
chromosome segregation GO:0007059 180 0.092
negative regulation of biological process GO:0048519 567 0.090
regulation of multicellular organism growth GO:0040014 373 0.089
developmental process involved in reproduction GO:0003006 1165 0.086
anatomical structure formation involved in morphogenesis GO:0048646 250 0.086
cellular macromolecular complex assembly GO:0034622 184 0.085
regulation of signal transduction GO:0009966 135 0.085
cellular protein complex assembly GO:0043623 178 0.084
regulation of nitrogen compound metabolic process GO:0051171 222 0.083
aging GO:0007568 812 0.081
regulation of developmental growth GO:0048638 389 0.081
actin cytoskeleton organization GO:0030036 184 0.079
cell projection organization GO:0030030 231 0.078
chromatin organization GO:0006325 32 0.077
canonical wnt signaling pathway GO:0060070 3 0.077
regulation of macromolecule metabolic process GO:0060255 421 0.076
gene expression GO:0010467 412 0.074
cellular component assembly GO:0022607 293 0.074
macromolecule biosynthetic process GO:0009059 250 0.073
regulation of macromolecule biosynthetic process GO:0010556 189 0.072
single organism localization GO:1902578 518 0.071
meiosis i GO:0007127 19 0.070
purine ribonucleotide metabolic process GO:0009150 95 0.067
regulation of nucleic acid templated transcription GO:1903506 165 0.067
lipid storage GO:0019915 565 0.066
apoptotic process GO:0006915 478 0.066
maintenance of location GO:0051235 580 0.066
programmed cell death GO:0012501 500 0.066
neuroblast fate determination GO:0007400 1 0.066
cell surface receptor signaling pathway GO:0007166 149 0.065
vesicle mediated transport GO:0016192 852 0.064
negative regulation of gene expression epigenetic GO:0045814 2 0.064
positive regulation of cellular biosynthetic process GO:0031328 109 0.064
positive regulation of cellular metabolic process GO:0031325 178 0.063
cell projection morphogenesis GO:0048858 148 0.062
reproductive behavior GO:0019098 387 0.062
polar body extrusion after meiotic divisions GO:0040038 14 0.060
lipid localization GO:0010876 573 0.060
signaling GO:0023052 401 0.059
regulation of cell cycle GO:0051726 194 0.058
macromolecular complex assembly GO:0065003 193 0.058
striated muscle cell differentiation GO:0051146 158 0.058
regulation of developmental process GO:0050793 684 0.058
response to chemical GO:0042221 356 0.057
multi organism reproductive behavior GO:0044705 387 0.057
regionalization GO:0003002 31 0.057
neuron projection morphogenesis GO:0048812 114 0.056
sister chromatid segregation GO:0000819 46 0.055
oocyte axis specification GO:0007309 2 0.055
regulation of catalytic activity GO:0050790 78 0.055
cellular localization GO:0051641 360 0.055
nervous system development GO:0007399 253 0.055
positive regulation of metabolic process GO:0009893 187 0.053
organic substance biosynthetic process GO:1901576 323 0.052
sensory organ morphogenesis GO:0090596 2 0.052
chromatin assembly or disassembly GO:0006333 1 0.052
regulation of multicellular organismal process GO:0051239 726 0.051
head development GO:0060322 1 0.051
developmental growth GO:0048589 412 0.050
nucleic acid metabolic process GO:0090304 299 0.050
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.050
phosphate containing compound metabolic process GO:0006796 232 0.048
protein complex assembly GO:0006461 186 0.048
membrane organization GO:0061024 135 0.048
pole plasm assembly GO:0007315 2 0.048
nucleobase containing compound metabolic process GO:0006139 406 0.047
histone modification GO:0016570 30 0.047
regulation of rna biosynthetic process GO:2001141 165 0.047
development of primary sexual characteristics GO:0045137 840 0.046
axon development GO:0061564 163 0.046
regulation of rna metabolic process GO:0051252 173 0.044
negative regulation of cellular metabolic process GO:0031324 95 0.044
phosphorus metabolic process GO:0006793 232 0.044
reproductive system development GO:0061458 850 0.043
organelle assembly GO:0070925 214 0.043
neurogenesis GO:0022008 236 0.043
cell death GO:0008219 547 0.042
regulation of cell communication GO:0010646 176 0.041
cellular component movement GO:0006928 388 0.040
regulation of chromosome organization GO:0033044 20 0.040
regulation of signaling GO:0023051 172 0.039
response to external stimulus GO:0009605 289 0.039
receptor mediated endocytosis GO:0006898 715 0.039
kinetochore assembly GO:0051382 5 0.038
regulation of cellular protein metabolic process GO:0032268 75 0.038
behavior GO:0007610 527 0.038
organic substance catabolic process GO:1901575 294 0.037
cell cycle phase transition GO:0044770 19 0.037
mitotic spindle organization GO:0007052 81 0.037
neuron differentiation GO:0030182 217 0.037
positive regulation of cell cycle GO:0045787 55 0.037
negative regulation of nucleic acid templated transcription GO:1903507 53 0.036
proximal distal axis specification GO:0009946 6 0.036
cellular catabolic process GO:0044248 199 0.036
regulation of transcription dna templated GO:0006355 164 0.036
gonad development GO:0008406 840 0.036
negative regulation of metabolic process GO:0009892 240 0.035
regulation of growth GO:0040008 409 0.035
ribonucleoside triphosphate metabolic process GO:0009199 87 0.035
sex differentiation GO:0007548 909 0.034
multi multicellular organism process GO:0044706 390 0.034
myofibril assembly GO:0030239 154 0.034
chromosome condensation GO:0030261 6 0.033
regulation of biosynthetic process GO:0009889 189 0.033
reproductive structure development GO:0048608 850 0.033
macromolecule catabolic process GO:0009057 202 0.033
digestive system development GO:0055123 122 0.033
negative regulation of gene expression GO:0010629 217 0.033
organelle localization GO:0051640 127 0.032
multicellular organism growth GO:0035264 385 0.032
regulation of mitotic cell cycle GO:0007346 76 0.032
regulation of cell proliferation GO:0042127 105 0.032
single fertilization GO:0007338 61 0.032
purine containing compound metabolic process GO:0072521 95 0.031
nucleic acid templated transcription GO:0097659 169 0.031
regulation of gene expression epigenetic GO:0040029 163 0.030
death GO:0016265 547 0.030
cellular component assembly involved in morphogenesis GO:0010927 183 0.030
regulation of chromosome segregation GO:0051983 20 0.030
posttranscriptional regulation of gene expression GO:0010608 166 0.030
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.030
regulation of bmp signaling pathway GO:0030510 3 0.030
regulation of canonical wnt signaling pathway GO:0060828 1 0.030
generation of neurons GO:0048699 235 0.030
actomyosin structure organization GO:0031032 154 0.029
positive regulation of catalytic activity GO:0043085 59 0.029
response to abiotic stimulus GO:0009628 152 0.029
modification dependent protein catabolic process GO:0019941 32 0.029
negative regulation of macromolecule metabolic process GO:0010605 229 0.029
cell morphogenesis involved in differentiation GO:0000904 112 0.028
neuron development GO:0048666 199 0.028
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.028
organ development GO:0048513 1102 0.028
protein localization GO:0008104 205 0.028
female meiotic division GO:0007143 17 0.028
centromere complex assembly GO:0034508 5 0.028
positive regulation of developmental growth GO:0048639 354 0.028
cell motility GO:0048870 313 0.027
positive regulation of mitotic sister chromatid separation GO:1901970 1 0.027
hermaphrodite germ line sex determination GO:0040021 48 0.027
system process GO:0003008 136 0.026
muscle cell development GO:0055001 158 0.026
negative regulation of transcription dna templated GO:0045892 53 0.026
establishment of localization in cell GO:0051649 318 0.026
germ line stem cell division GO:0042078 9 0.026
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.025
aromatic compound biosynthetic process GO:0019438 192 0.025
ribonucleoside metabolic process GO:0009119 98 0.025
organophosphate metabolic process GO:0019637 125 0.025
meiotic cytokinesis GO:0033206 15 0.025
chemotaxis GO:0006935 120 0.025
heterocycle catabolic process GO:0046700 119 0.024
striated muscle cell development GO:0055002 157 0.024
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.024
rna localization GO:0006403 3 0.024
nuclear migration GO:0007097 54 0.024
proteolysis involved in cellular protein catabolic process GO:0051603 32 0.024
oocyte construction GO:0007308 2 0.024
positive regulation of stem cell differentiation GO:2000738 1 0.024
positive regulation of macromolecule metabolic process GO:0010604 149 0.024
pattern specification process GO:0007389 59 0.023
tube development GO:0035295 126 0.023
ribonucleoside triphosphate catabolic process GO:0009203 72 0.023
axis specification GO:0009798 23 0.023
nucleus localization GO:0051647 55 0.023
dendrite development GO:0016358 42 0.023
heterocycle biosynthetic process GO:0018130 187 0.023
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.022
wnt signaling pathway GO:0016055 27 0.022
cytoskeleton dependent cytokinesis GO:0061640 35 0.022
striated muscle myosin thick filament assembly GO:0071688 138 0.022
chromatin modification GO:0016568 32 0.022
cell morphogenesis GO:0000902 163 0.021
dna metabolic process GO:0006259 74 0.021
organonitrogen compound metabolic process GO:1901564 151 0.021
neuron recognition GO:0008038 83 0.021
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.021
regulation of mitosis GO:0007088 18 0.021
glycosyl compound metabolic process GO:1901657 100 0.021
positive regulation of meiotic cell cycle GO:0051446 47 0.021
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.020
germ line sex determination GO:0018992 51 0.020
microtubule based process GO:0007017 182 0.020
male sex differentiation GO:0046661 86 0.020
chromatin remodeling GO:0006338 2 0.020
synaptonemal complex assembly GO:0007130 6 0.020
meiosis ii GO:0007135 16 0.020
ribonucleotide metabolic process GO:0009259 99 0.020
negative regulation of signaling GO:0023057 61 0.020
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.020
nucleoside phosphate metabolic process GO:0006753 108 0.020
organic substance transport GO:0071702 113 0.020
male anatomical structure morphogenesis GO:0090598 78 0.020
apical junction assembly GO:0043297 1 0.020
muscle cell differentiation GO:0042692 171 0.019
phosphorylation GO:0016310 116 0.019
negative regulation of chromosome segregation GO:0051985 4 0.019
positive regulation of growth GO:0045927 369 0.019
modification dependent macromolecule catabolic process GO:0043632 32 0.019
positive regulation of multicellular organism growth GO:0040018 352 0.019
positive regulation of developmental process GO:0051094 408 0.019
positive regulation of protein metabolic process GO:0051247 45 0.019
purine nucleotide catabolic process GO:0006195 75 0.019
nematode male tail tip morphogenesis GO:0045138 77 0.019
taxis GO:0042330 128 0.018
mitotic chromosome condensation GO:0007076 3 0.018
genitalia development GO:0048806 741 0.018
cellular macromolecule biosynthetic process GO:0034645 247 0.018
intracellular transport GO:0046907 77 0.018
positive regulation of cellular component organization GO:0051130 34 0.018
nucleobase containing small molecule metabolic process GO:0055086 115 0.018
sex determination GO:0007530 60 0.018
regulation of phosphorus metabolic process GO:0051174 81 0.018
positive regulation of intracellular transport GO:0032388 2 0.018
intracellular signal transduction GO:0035556 96 0.018
positive regulation of chromosome organization GO:2001252 2 0.017
nucleoside phosphate catabolic process GO:1901292 77 0.017
cellular nitrogen compound biosynthetic process GO:0044271 192 0.017
gene silencing GO:0016458 143 0.017
nucleoside triphosphate catabolic process GO:0009143 72 0.017
myosin filament assembly GO:0031034 138 0.017
regulation of molecular function GO:0065009 89 0.017
long term memory GO:0007616 2 0.017
biosynthetic process GO:0009058 323 0.017
guanosine containing compound metabolic process GO:1901068 49 0.017
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.017
nucleotide metabolic process GO:0009117 108 0.017
regulation of response to stimulus GO:0048583 243 0.017
single organism transport GO:0044765 447 0.016
protein catabolic process GO:0030163 162 0.016
body morphogenesis GO:0010171 620 0.016
cell proliferation GO:0008283 116 0.016
response to heat GO:0009408 50 0.016
cellular response to stress GO:0033554 162 0.016
negative regulation of bmp signaling pathway GO:0030514 1 0.016
male gamete generation GO:0048232 41 0.016
spermatogenesis GO:0007283 41 0.016
single organism intracellular transport GO:1902582 70 0.016
negative regulation of nucleoside metabolic process GO:0045978 5 0.016
regulation of cellular catabolic process GO:0031329 51 0.016
bmp signaling pathway GO:0030509 3 0.016
dna duplex unwinding GO:0032508 3 0.015
nucleoside metabolic process GO:0009116 99 0.015
small molecule metabolic process GO:0044281 186 0.015
organic cyclic compound biosynthetic process GO:1901362 195 0.015
negative regulation of cell cycle GO:0045786 53 0.015
internal peptidyl lysine acetylation GO:0018393 3 0.015
mitochondrion organization GO:0007005 20 0.015
cytokinesis GO:0000910 80 0.015
meiotic sister chromatid segregation GO:0045144 15 0.015
polarity specification of proximal distal axis GO:0010085 6 0.015
asymmetric protein localization GO:0008105 35 0.015
ribonucleotide catabolic process GO:0009261 75 0.015
neuron projection guidance GO:0097485 82 0.015
positive regulation of cellular catabolic process GO:0031331 35 0.015
organophosphate catabolic process GO:0046434 81 0.014
positive regulation of multicellular organismal process GO:0051240 417 0.014
negative regulation of rna biosynthetic process GO:1902679 53 0.014
peptidyl amino acid modification GO:0018193 58 0.014
reciprocal meiotic recombination GO:0007131 11 0.014
nucleoside catabolic process GO:0009164 78 0.014
regulation of protein targeting GO:1903533 3 0.014
single organism catabolic process GO:0044712 129 0.014
digestive tract development GO:0048565 122 0.014
purine nucleoside catabolic process GO:0006152 75 0.014
aromatic compound catabolic process GO:0019439 116 0.014
cell recognition GO:0008037 85 0.014
regulation of cytoplasmic transport GO:1903649 3 0.014
carbohydrate derivative catabolic process GO:1901136 82 0.013
anterior posterior axis specification GO:0009948 17 0.013
negative regulation of neurogenesis GO:0050768 4 0.013
purine nucleotide metabolic process GO:0006163 95 0.013
regulation of apoptotic signaling pathway GO:2001233 1 0.013
collagen and cuticulin based cuticle development GO:0040002 99 0.013
ribose phosphate metabolic process GO:0019693 99 0.013
epithelial tube morphogenesis GO:0060562 1 0.013
negative regulation of developmental process GO:0051093 227 0.013
hermaphrodite genitalia development GO:0040035 734 0.013
regulation of cellular ketone metabolic process GO:0010565 3 0.013
rna metabolic process GO:0016070 228 0.013
axonal fasciculation GO:0007413 79 0.013
negative regulation of biosynthetic process GO:0009890 65 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.013
response to temperature stimulus GO:0009266 66 0.013
defense response GO:0006952 296 0.013
regulation of stem cell differentiation GO:2000736 1 0.012
oxoacid metabolic process GO:0043436 47 0.012
cellular macromolecule localization GO:0070727 75 0.012
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 1 0.012
regulation of nematode larval development GO:0061062 260 0.012
negative regulation of signal transduction GO:0009968 60 0.012
negative regulation of response to stimulus GO:0048585 73 0.012
proteolysis GO:0006508 61 0.012
single organism membrane organization GO:0044802 35 0.012
phagocytosis engulfment GO:0006911 98 0.012
regulation of embryonic development GO:0045995 16 0.012
positive regulation of cellular protein catabolic process GO:1903364 3 0.012
transcription dna templated GO:0006351 168 0.011
protein polymerization GO:0051258 26 0.011
nucleotide catabolic process GO:0009166 77 0.011
regulation of cell differentiation GO:0045595 81 0.011
dna conformation change GO:0071103 11 0.011
molting cycle GO:0042303 281 0.011
myosin filament organization GO:0031033 138 0.011
regulation of protein import into nucleus GO:0042306 3 0.011
nucleobase containing compound biosynthetic process GO:0034654 184 0.011
single organism cellular localization GO:1902580 72 0.011
purine nucleoside triphosphate metabolic process GO:0009144 87 0.011
stem cell division GO:0017145 18 0.011
regulation of cytoskeleton organization GO:0051493 41 0.011
positive regulation of rna biosynthetic process GO:1902680 102 0.011
regulation of multicellular organismal development GO:2000026 317 0.011
glycosyl compound catabolic process GO:1901658 79 0.011
ras protein signal transduction GO:0007265 31 0.011
metaphase anaphase transition of cell cycle GO:0044784 15 0.011
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 4 0.011
regulation of chromatin modification GO:1903308 2 0.011
g1 s transition of mitotic cell cycle GO:0000082 2 0.010
epithelial cell morphogenesis GO:0003382 2 0.010
protein modification by small protein conjugation or removal GO:0070647 40 0.010
purine ribonucleoside metabolic process GO:0046128 92 0.010
microtubule based movement GO:0007018 33 0.010
protein phosphorylation GO:0006468 85 0.010
protein modification by small protein conjugation GO:0032446 31 0.010
mitotic g2 m transition checkpoint GO:0044818 1 0.010
negative regulation of mitotic cell cycle GO:0045930 42 0.010

klp-18 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.026
disease of anatomical entity DOID:7 0 0.026
bone marrow disease DOID:4961 0 0.026
hematopoietic system disease DOID:74 0 0.026
cardiovascular system disease DOID:1287 0 0.017
heart disease DOID:114 0 0.010