Caenorhabditis elegans

35 known processes

apm-1 (CELE_F55A12.7)

Protein APM-1

apm-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
apoptotic process GO:0006915 478 0.205
positive regulation of developmental process GO:0051094 408 0.185
embryo development ending in birth or egg hatching GO:0009792 2992 0.157
Worm
death GO:0016265 547 0.144
embryo development GO:0009790 3052 0.129
Worm
cell death GO:0008219 547 0.123
negative regulation of biological process GO:0048519 567 0.119
cellular biosynthetic process GO:0044249 315 0.118
multicellular organism growth GO:0035264 385 0.115
head development GO:0060322 1 0.108
Zebrafish
gene expression GO:0010467 412 0.105
multicellular organismal aging GO:0010259 812 0.103
dauer larval development GO:0040024 92 0.102
single organism reproductive process GO:0044702 1196 0.101
body morphogenesis GO:0010171 620 0.100
Worm
macromolecule localization GO:0033036 771 0.099
determination of adult lifespan GO:0008340 812 0.097
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.097
molting cycle GO:0042303 281 0.089
hermaphrodite genitalia development GO:0040035 734 0.089
multi organism reproductive process GO:0044703 867 0.083
regulation of biological quality GO:0065008 741 0.082
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.080
multicellular organismal reproductive process GO:0048609 815 0.079
developmental process involved in reproduction GO:0003006 1165 0.077
organic cyclic compound biosynthetic process GO:1901362 195 0.076
positive regulation of developmental growth GO:0048639 354 0.075
maintenance of location GO:0051235 580 0.072
regulation of macromolecule metabolic process GO:0060255 421 0.071
regulation of transcription dna templated GO:0006355 164 0.070
locomotion GO:0040011 1634 0.070
positive regulation of growth GO:0045927 369 0.068
cation homeostasis GO:0055080 20 0.068
establishment of localization GO:0051234 1171 0.068
lipid localization GO:0010876 573 0.066
positive regulation of multicellular organism growth GO:0040018 352 0.065
programmed cell death GO:0012501 500 0.065
lipid storage GO:0019915 565 0.065
multicellular organism reproduction GO:0032504 819 0.064
regulation of rna biosynthetic process GO:2001141 165 0.064
reproductive behavior GO:0019098 387 0.064
regulation of developmental process GO:0050793 684 0.060
collagen and cuticulin based cuticle development GO:0040002 99 0.060
regulation of metabolic process GO:0019222 478 0.060
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.059
rna metabolic process GO:0016070 228 0.057
behavior GO:0007610 527 0.057
multicellular organismal reproductive behavior GO:0033057 384 0.056
growth GO:0040007 562 0.056
cellular nitrogen compound biosynthetic process GO:0044271 192 0.055
single organism localization GO:1902578 518 0.054
vesicle mediated transport GO:0016192 852 0.053
Yeast Zebrafish
multi organism behavior GO:0051705 389 0.053
sexual reproduction GO:0019953 546 0.052
meiotic nuclear division GO:0007126 300 0.052
aging GO:0007568 812 0.051
regulation of cell division GO:0051302 142 0.051
transport GO:0006810 1093 0.050
transcription from rna polymerase ii promoter GO:0006366 149 0.050
post embryonic development GO:0009791 2152 0.050
regulation of localization GO:0032879 194 0.049
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.048
cellular response to organic substance GO:0071310 119 0.048
regulation of rna metabolic process GO:0051252 173 0.048
small molecule metabolic process GO:0044281 186 0.047
positive regulation of multicellular organismal process GO:0051240 417 0.047
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.047
reproductive structure development GO:0048608 850 0.047
negative regulation of nucleic acid templated transcription GO:1903507 53 0.046
nucleobase containing compound metabolic process GO:0006139 406 0.046
regulation of multicellular organismal process GO:0051239 726 0.046
cuticle development GO:0042335 100 0.045
sex differentiation GO:0007548 909 0.044
development of primary sexual characteristics GO:0045137 840 0.044
regulation of nitrogen compound metabolic process GO:0051171 222 0.043
negative regulation of gene expression GO:0010629 217 0.043
germ cell development GO:0007281 351 0.043
genitalia development GO:0048806 741 0.043
positive regulation of rna metabolic process GO:0051254 103 0.042
single organism behavior GO:0044708 83 0.042
regulation of gene expression GO:0010468 366 0.042
multi organism reproductive behavior GO:0044705 387 0.041
establishment of localization in cell GO:0051649 318 0.040
rna biosynthetic process GO:0032774 169 0.040
receptor mediated endocytosis GO:0006898 715 0.039
developmental growth GO:0048589 412 0.039
regulation of primary metabolic process GO:0080090 292 0.038
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.038
nucleic acid templated transcription GO:0097659 169 0.037
organonitrogen compound metabolic process GO:1901564 151 0.037
biosynthetic process GO:0009058 323 0.037
regulation of growth GO:0040008 409 0.036
negative regulation of cellular metabolic process GO:0031324 95 0.036
cell cycle GO:0007049 526 0.036
cell proliferation GO:0008283 116 0.036
multi multicellular organism process GO:0044706 390 0.035
regulation of cellular metabolic process GO:0031323 305 0.035
oviposition GO:0018991 364 0.035
negative regulation of metabolic process GO:0009892 240 0.034
female gamete generation GO:0007292 254 0.033
cellular response to topologically incorrect protein GO:0035967 76 0.033
adult behavior GO:0030534 3 0.033
response to external stimulus GO:0009605 289 0.032
regulation of hormone secretion GO:0046883 2 0.032
negative regulation of macromolecule metabolic process GO:0010605 229 0.032
organic substance biosynthetic process GO:1901576 323 0.032
regulation of macromolecule biosynthetic process GO:0010556 189 0.031
regulation of multicellular organism growth GO:0040014 373 0.031
nucleic acid metabolic process GO:0090304 299 0.031
organelle fission GO:0048285 363 0.031
localization within membrane GO:0051668 2 0.030
gene silencing GO:0016458 143 0.029
oogenesis GO:0048477 229 0.029
organelle organization GO:0006996 783 0.029
Worm
response to other organism GO:0051707 101 0.028
signaling GO:0023052 401 0.027
cell development GO:0048468 696 0.026
endoplasmic reticulum unfolded protein response GO:0030968 66 0.026
regulation of developmental growth GO:0048638 389 0.026
response to chemical GO:0042221 356 0.026
nucleus organization GO:0006997 38 0.026
endocytosis GO:0006897 819 0.026
macromolecule biosynthetic process GO:0009059 250 0.025
positive regulation of transcription dna templated GO:0045893 102 0.025
positive regulation of epithelial cell proliferation GO:0050679 1 0.025
muscle tissue development GO:0060537 1 0.025
reproductive system development GO:0061458 850 0.025
chemical homeostasis GO:0048878 29 0.025
positive regulation of cellular process GO:0048522 332 0.024
posttranscriptional regulation of gene expression GO:0010608 166 0.024
response to external biotic stimulus GO:0043207 101 0.024
regulation of nucleic acid templated transcription GO:1903506 165 0.024
defense response to bacterium GO:0042742 86 0.024
regulation of nuclear division GO:0051783 115 0.024
cellular macromolecule biosynthetic process GO:0034645 247 0.023
sensory organ morphogenesis GO:0090596 2 0.023
nucleobase containing small molecule metabolic process GO:0055086 115 0.023
macromolecule modification GO:0043412 218 0.022
heterocycle biosynthetic process GO:0018130 187 0.022
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.021
defense response to gram negative bacterium GO:0050829 64 0.021
phagocytosis GO:0006909 115 0.021
cellular response to stress GO:0033554 162 0.021
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.021
positive regulation of macromolecule metabolic process GO:0010604 149 0.021
regulation of nematode larval development GO:0061062 260 0.021
cell cycle process GO:0022402 482 0.021
rna interference GO:0016246 137 0.021
er nucleus signaling pathway GO:0006984 66 0.020
aromatic compound biosynthetic process GO:0019438 192 0.020
heterocycle catabolic process GO:0046700 119 0.020
protein metabolic process GO:0019538 422 0.020
muscle organ morphogenesis GO:0048644 4 0.020
single organism organelle organization GO:1902589 501 0.020
Worm
cellular localization GO:0051641 360 0.020
regulation of cellular localization GO:0060341 42 0.020
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.020
regulation of cell proliferation GO:0042127 105 0.019
acetate ester transport GO:1901374 16 0.019
nematode male tail tip morphogenesis GO:0045138 77 0.019
response to endoplasmic reticulum stress GO:0034976 71 0.019
striated muscle cell differentiation GO:0051146 158 0.019
negative regulation of gene expression epigenetic GO:0045814 2 0.019
cellular protein metabolic process GO:0044267 279 0.019
regulation of cellular biosynthetic process GO:0031326 189 0.019
mitotic cell cycle process GO:1903047 194 0.019
synaptic target recognition GO:0008039 3 0.018
nucleoside phosphate metabolic process GO:0006753 108 0.018
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.018
regulation of gene expression epigenetic GO:0040029 163 0.018
organelle localization GO:0051640 127 0.018
response to topologically incorrect protein GO:0035966 82 0.018
establishment of rna localization GO:0051236 3 0.018
regulation of biosynthetic process GO:0009889 189 0.018
membrane organization GO:0061024 135 0.018
nitrogen compound transport GO:0071705 49 0.018
transcription dna templated GO:0006351 168 0.018
male anatomical structure morphogenesis GO:0090598 78 0.018
digestive system development GO:0055123 122 0.018
Zebrafish
alpha amino acid metabolic process GO:1901605 10 0.017
cellular macromolecular complex assembly GO:0034622 184 0.017
single organism catabolic process GO:0044712 129 0.017
single organism transport GO:0044765 447 0.017
generation of neurons GO:0048699 235 0.017
adult locomotory behavior GO:0008344 1 0.017
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.016
regulation of protein metabolic process GO:0051246 81 0.016
gonad development GO:0008406 840 0.016
protein localization GO:0008104 205 0.016
organic acid metabolic process GO:0006082 47 0.016
secretion GO:0046903 147 0.016
negative regulation of cellular biosynthetic process GO:0031327 65 0.016
meiotic cell cycle GO:0051321 335 0.016
carboxylic acid catabolic process GO:0046395 3 0.016
organic substance transport GO:0071702 113 0.015
cellular amino acid metabolic process GO:0006520 15 0.015
metal ion transport GO:0030001 49 0.015
epithelial cell proliferation GO:0050673 1 0.015
defense response GO:0006952 296 0.015
nucleobase containing compound biosynthetic process GO:0034654 184 0.015
cell division GO:0051301 262 0.015
regulation of vulval development GO:0040028 248 0.015
divalent metal ion transport GO:0070838 17 0.014
negative regulation of biosynthetic process GO:0009890 65 0.014
positive regulation of biosynthetic process GO:0009891 109 0.014
cellular nitrogen compound catabolic process GO:0044270 119 0.014
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.014
regulation of apoptotic signaling pathway GO:2001233 1 0.014
regulation of cell cycle GO:0051726 194 0.014
catabolic process GO:0009056 318 0.014
response to unfolded protein GO:0006986 71 0.014
organic acid catabolic process GO:0016054 3 0.014
muscle cell differentiation GO:0042692 171 0.014
translation GO:0006412 37 0.014
posttranscriptional gene silencing GO:0016441 143 0.014
phagocytosis engulfment GO:0006911 98 0.014
cation transport GO:0006812 78 0.013
establishment of organelle localization GO:0051656 123 0.013
macromolecular complex subunit organization GO:0043933 320 0.013
organelle assembly GO:0070925 214 0.013
Worm
cellular component assembly involved in morphogenesis GO:0010927 183 0.013
Worm
amine metabolic process GO:0009308 15 0.013
cellular response to chemical stimulus GO:0070887 129 0.013
nuclear migration GO:0007097 54 0.013
single organism biosynthetic process GO:0044711 91 0.013
negative regulation of rna metabolic process GO:0051253 53 0.013
negative regulation of cellular process GO:0048523 239 0.013
nervous system development GO:0007399 253 0.013
Zebrafish
regulation of transport GO:0051049 91 0.013
rna localization GO:0006403 3 0.012
digestive tract development GO:0048565 122 0.012
Zebrafish
regulation of multicellular organismal development GO:2000026 317 0.012
single organism signaling GO:0044700 401 0.012
hormone transport GO:0009914 2 0.012
posttranscriptional gene silencing by rna GO:0035194 143 0.012
aromatic compound catabolic process GO:0019439 116 0.012
regulation of programmed cell death GO:0043067 50 0.012
nucleic acid transport GO:0050657 3 0.012
enzyme linked receptor protein signaling pathway GO:0007167 50 0.012
myosin filament organization GO:0031033 138 0.012
lipid metabolic process GO:0006629 77 0.012
cellular protein localization GO:0034613 75 0.012
Worm
cellular component assembly GO:0022607 293 0.012
Worm
engulfment of apoptotic cell GO:0043652 94 0.011
cell morphogenesis GO:0000902 163 0.011
Worm
pharynx development GO:0060465 51 0.011
negative regulation of rna biosynthetic process GO:1902679 53 0.011
regulation of meiosis GO:0040020 94 0.011
muscle structure development GO:0061061 191 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.011
protein modification process GO:0036211 207 0.011
regulation of post embryonic development GO:0048580 260 0.011
rna transport GO:0050658 3 0.011
gamete generation GO:0007276 461 0.011
response to bacterium GO:0009617 86 0.011
axonal fasciculation GO:0007413 79 0.011
positive regulation of nematode larval development GO:0061063 54 0.011
cell recognition GO:0008037 85 0.011
purine nucleoside triphosphate metabolic process GO:0009144 87 0.011
organic cyclic compound catabolic process GO:1901361 119 0.011
intracellular signal transduction GO:0035556 96 0.011
ribonucleoside metabolic process GO:0009119 98 0.011
carboxylic acid metabolic process GO:0019752 34 0.011
neurotransmitter secretion GO:0007269 26 0.011
organonitrogen compound catabolic process GO:1901565 90 0.011
cellular catabolic process GO:0044248 199 0.011
oxoacid metabolic process GO:0043436 47 0.010
regulation of epithelial cell proliferation GO:0050678 1 0.010
microtubule based movement GO:0007018 33 0.010
negative regulation of transcription dna templated GO:0045892 53 0.010
detection of abiotic stimulus GO:0009582 4 0.010
positive regulation of nucleic acid templated transcription GO:1903508 102 0.010
gene silencing by rna GO:0031047 143 0.010
positive regulation of cellular biosynthetic process GO:0031328 109 0.010
response to osmotic stress GO:0006970 29 0.010
organophosphate metabolic process GO:0019637 125 0.010
immune response GO:0006955 192 0.010

apm-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016
lipodystrophy DOID:811 0 0.012
skin disease DOID:37 0 0.012
integumentary system disease DOID:16 0 0.012
familial partial lipodystrophy DOID:0050440 0 0.012
progeria DOID:3911 0 0.011