Caenorhabditis elegans

39 known processes

sams-4 (CELE_C06E7.3)

Protein SAMS-4

sams-4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.638
Worm
reproductive system development GO:0061458 850 0.485
heterocycle biosynthetic process GO:0018130 187 0.400
Human
embryo development ending in birth or egg hatching GO:0009792 2992 0.381
Worm
endocytosis GO:0006897 819 0.355
Worm
locomotion GO:0040011 1634 0.349
post embryonic development GO:0009791 2152 0.346
Worm
regulation of metabolic process GO:0019222 478 0.343
Worm
hermaphrodite genitalia development GO:0040035 734 0.330
secretion by cell GO:0032940 138 0.327
vesicle mediated transport GO:0016192 852 0.311
Worm
phosphorus metabolic process GO:0006793 232 0.301
purine containing compound metabolic process GO:0072521 95 0.274
Human
organ development GO:0048513 1102 0.260
development of primary sexual characteristics GO:0045137 840 0.255
small molecule metabolic process GO:0044281 186 0.214
Human
nucleobase containing compound biosynthetic process GO:0034654 184 0.201
Human
gonad development GO:0008406 840 0.189
autophagy GO:0006914 29 0.188
establishment of localization in cell GO:0051649 318 0.183
nucleobase containing compound metabolic process GO:0006139 406 0.181
Human
organelle organization GO:0006996 783 0.180
regulation of gene expression GO:0010468 366 0.177
Worm
cell development GO:0048468 696 0.177
Zebrafish
determination of adult lifespan GO:0008340 812 0.170
Worm
organonitrogen compound metabolic process GO:1901564 151 0.162
Human
organic substance biosynthetic process GO:1901576 323 0.158
Human Worm
establishment of localization GO:0051234 1171 0.153
aging GO:0007568 812 0.150
Worm
negative regulation of biological process GO:0048519 567 0.147
Worm
cellular biosynthetic process GO:0044249 315 0.147
Human Worm
multicellular organismal aging GO:0010259 812 0.137
Worm
body morphogenesis GO:0010171 620 0.128
regulation of developmental process GO:0050793 684 0.128
Worm
posttranscriptional gene silencing GO:0016441 143 0.123
Worm
phosphate containing compound metabolic process GO:0006796 232 0.123
regulation of macromolecule metabolic process GO:0060255 421 0.122
Worm
reproductive structure development GO:0048608 850 0.121
transport GO:0006810 1093 0.121
biosynthetic process GO:0009058 323 0.120
Human Worm
developmental process involved in reproduction GO:0003006 1165 0.116
cell death GO:0008219 547 0.115
macromolecule localization GO:0033036 771 0.114
carbohydrate derivative metabolic process GO:1901135 141 0.114
Human
nucleobase containing small molecule metabolic process GO:0055086 115 0.113
Human
developmental growth GO:0048589 412 0.111
Worm
positive regulation of cellular metabolic process GO:0031325 178 0.110
gene silencing GO:0016458 143 0.109
Worm
multicellular organism reproduction GO:0032504 819 0.108
cellular localization GO:0051641 360 0.108
single organism reproductive process GO:0044702 1196 0.105
regulation of biological quality GO:0065008 741 0.104
macromolecule biosynthetic process GO:0009059 250 0.102
Worm
meiotic cell cycle process GO:1903046 170 0.100
receptor mediated endocytosis GO:0006898 715 0.100
Worm
cellular catabolic process GO:0044248 199 0.099
ribonucleoside metabolic process GO:0009119 98 0.098
Human
cellular nitrogen compound biosynthetic process GO:0044271 192 0.097
Human
single organism localization GO:1902578 518 0.096
organelle fission GO:0048285 363 0.095
gene silencing by rna GO:0031047 143 0.094
Worm
regulation of multicellular organismal process GO:0051239 726 0.093
Worm
single organism catabolic process GO:0044712 129 0.090
nucleoside metabolic process GO:0009116 99 0.090
Human
purine ribonucleoside metabolic process GO:0046128 92 0.085
Human
positive regulation of developmental growth GO:0048639 354 0.085
Worm
ribonucleoside triphosphate metabolic process GO:0009199 87 0.081
protein metabolic process GO:0019538 422 0.081
Worm
sex differentiation GO:0007548 909 0.081
muscle tissue development GO:0060537 1 0.081
Zebrafish
lipid metabolic process GO:0006629 77 0.081
Worm
cell cycle GO:0007049 526 0.080
genitalia development GO:0048806 741 0.080
cellular response to chemical stimulus GO:0070887 129 0.079
regulation of macromolecule biosynthetic process GO:0010556 189 0.078
positive regulation of catabolic process GO:0009896 38 0.078
single organism transport GO:0044765 447 0.076
posttranscriptional regulation of gene expression GO:0010608 166 0.076
Worm
nucleoside phosphate metabolic process GO:0006753 108 0.075
lipid localization GO:0010876 573 0.075
maintenance of location GO:0051235 580 0.073
secretion GO:0046903 147 0.072
gene expression GO:0010467 412 0.072
Worm
protein complex subunit organization GO:0071822 280 0.071
regulation of developmental growth GO:0048638 389 0.070
Worm
negative regulation of gene expression GO:0010629 217 0.069
Worm
organophosphate metabolic process GO:0019637 125 0.069
muscle structure development GO:0061061 191 0.068
Zebrafish
purine nucleoside metabolic process GO:0042278 92 0.068
Human
growth GO:0040007 562 0.068
Worm
death GO:0016265 547 0.067
cellular protein modification process GO:0006464 207 0.066
carboxylic acid metabolic process GO:0019752 34 0.066
Human
regulation of cellular biosynthetic process GO:0031326 189 0.066
positive regulation of growth GO:0045927 369 0.065
Worm
oxoacid metabolic process GO:0043436 47 0.064
Human
organic cyclic compound biosynthetic process GO:1901362 195 0.064
Human
nucleotide metabolic process GO:0009117 108 0.063
coenzyme metabolic process GO:0006732 9 0.063
Human
regulation of post embryonic development GO:0048580 260 0.062
Worm
lipid storage GO:0019915 565 0.062
regulation of gene expression epigenetic GO:0040029 163 0.061
Worm
purine nucleotide metabolic process GO:0006163 95 0.061
response to external stimulus GO:0009605 289 0.061
negative regulation of macromolecule metabolic process GO:0010605 229 0.061
Worm
posttranscriptional gene silencing by rna GO:0035194 143 0.060
Worm
positive regulation of multicellular organismal process GO:0051240 417 0.060
Worm
behavior GO:0007610 527 0.060
positive regulation of cellular process GO:0048522 332 0.057
molting cycle GO:0042303 281 0.056
regulation of vulval development GO:0040028 248 0.056
Worm
catabolic process GO:0009056 318 0.056
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.056
regulation of rna metabolic process GO:0051252 173 0.056
regulation of primary metabolic process GO:0080090 292 0.055
rna interference GO:0016246 137 0.055
Worm
meiotic nuclear division GO:0007126 300 0.055
negative regulation of metabolic process GO:0009892 240 0.054
Worm
regulation of nitrogen compound metabolic process GO:0051171 222 0.053
cellular protein metabolic process GO:0044267 279 0.053
Worm
cellular component assembly GO:0022607 293 0.053
positive regulation of developmental process GO:0051094 408 0.053
Worm
cellular macromolecule biosynthetic process GO:0034645 247 0.052
Worm
multicellular organismal reproductive process GO:0048609 815 0.052
meiotic cell cycle GO:0051321 335 0.051
cellular component morphogenesis GO:0032989 318 0.051
regulation of localization GO:0032879 194 0.050
Worm
protein modification process GO:0036211 207 0.050
regulation of growth GO:0040008 409 0.050
Worm
negative regulation of cellular process GO:0048523 239 0.050
cellular component biogenesis GO:0044085 297 0.050
regulation of cellular metabolic process GO:0031323 305 0.049
ribose phosphate metabolic process GO:0019693 99 0.048
striated muscle cell development GO:0055002 157 0.047
Zebrafish
macromolecule modification GO:0043412 218 0.047
cellular component movement GO:0006928 388 0.046
multicellular organismal reproductive behavior GO:0033057 384 0.045
meiotic chromosome segregation GO:0045132 139 0.045
ribonucleotide metabolic process GO:0009259 99 0.045
cellular response to stress GO:0033554 162 0.045
cell division GO:0051301 262 0.045
positive regulation of cellular catabolic process GO:0031331 35 0.045
glycosyl compound metabolic process GO:1901657 100 0.044
Human
muscle cell differentiation GO:0042692 171 0.044
Zebrafish
programmed cell death GO:0012501 500 0.043
positive regulation of metabolic process GO:0009893 187 0.043
cell cycle process GO:0022402 482 0.043
cellular protein complex assembly GO:0043623 178 0.042
striated muscle cell differentiation GO:0051146 158 0.042
Zebrafish
response to chemical GO:0042221 356 0.041
regulation of signaling GO:0023051 172 0.041
multicellular organism growth GO:0035264 385 0.041
Worm
regulation of multicellular organism growth GO:0040014 373 0.041
Worm
protein localization GO:0008104 205 0.040
vulval development GO:0040025 333 0.040
Worm
protein complex biogenesis GO:0070271 186 0.040
regulation of cell division GO:0051302 142 0.040
single organism biosynthetic process GO:0044711 91 0.040
Human
regulation of locomotion GO:0040012 161 0.039
ribonucleoside catabolic process GO:0042454 77 0.039
regulation of response to stimulus GO:0048583 243 0.038
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.038
regulation of cell communication GO:0010646 176 0.038
regulation of cellular component organization GO:0051128 248 0.037
chromosome segregation GO:0007059 180 0.037
apoptotic process GO:0006915 478 0.036
response to organic substance GO:0010033 131 0.036
cellular response to organic substance GO:0071310 119 0.036
regulation of cellular protein metabolic process GO:0032268 75 0.036
muscle cell development GO:0055001 158 0.035
Zebrafish
regulation of biosynthetic process GO:0009889 189 0.035
oviposition GO:0018991 364 0.035
regulation of nematode larval development GO:0061062 260 0.035
Worm
organic acid metabolic process GO:0006082 47 0.035
Human
nucleic acid templated transcription GO:0097659 169 0.035
protein complex assembly GO:0006461 186 0.034
response to external biotic stimulus GO:0043207 101 0.034
macromolecular complex subunit organization GO:0043933 320 0.034
purine nucleoside triphosphate metabolic process GO:0009144 87 0.033
positive regulation of multicellular organism growth GO:0040018 352 0.033
Worm
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.033
neuron development GO:0048666 199 0.032
negative regulation of multicellular organismal process GO:0051241 236 0.032
Worm
aromatic compound biosynthetic process GO:0019438 192 0.031
Human
cell migration GO:0016477 306 0.031
regulation of nucleic acid templated transcription GO:1903506 165 0.031
phosphorylation GO:0016310 116 0.031
establishment of protein localization to membrane GO:0090150 3 0.031
purine nucleoside triphosphate catabolic process GO:0009146 72 0.030
cytoskeleton organization GO:0007010 339 0.030
multi organism reproductive behavior GO:0044705 387 0.030
head development GO:0060322 1 0.030
single organism intracellular transport GO:1902582 70 0.030
regulation of cellular catabolic process GO:0031329 51 0.030
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.030
transcription dna templated GO:0006351 168 0.029
gamete generation GO:0007276 461 0.029
multi multicellular organism process GO:0044706 390 0.029
organonitrogen compound biosynthetic process GO:1901566 44 0.029
Human
organic substance transport GO:0071702 113 0.029
multi organism behavior GO:0051705 389 0.029
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.029
rna biosynthetic process GO:0032774 169 0.029
organic substance catabolic process GO:1901575 294 0.028
actin cytoskeleton organization GO:0030036 184 0.028
negative regulation of developmental process GO:0051093 227 0.028
Worm
reproductive behavior GO:0019098 387 0.028
purine containing compound catabolic process GO:0072523 75 0.028
membrane organization GO:0061024 135 0.028
fertilization GO:0009566 63 0.027
protein localization to endoplasmic reticulum GO:0070972 2 0.027
regulation of cell cycle GO:0051726 194 0.027
cell morphogenesis GO:0000902 163 0.027
cellular amino acid metabolic process GO:0006520 15 0.027
Human
negative regulation of nematode larval development GO:0061064 208 0.027
Worm
multi organism reproductive process GO:0044703 867 0.027
regulation of catabolic process GO:0009894 57 0.027
neuron projection development GO:0031175 187 0.026
oxidation reduction process GO:0055114 59 0.026
regulation of meiotic cell cycle GO:0051445 136 0.026
small molecule biosynthetic process GO:0044283 38 0.026
Human
neuron projection morphogenesis GO:0048812 114 0.026
nucleic acid metabolic process GO:0090304 299 0.026
nucleobase containing compound catabolic process GO:0034655 114 0.026
cation transport GO:0006812 78 0.026
neurogenesis GO:0022008 236 0.026
response to wounding GO:0009611 4 0.026
aromatic compound catabolic process GO:0019439 116 0.025
neuron differentiation GO:0030182 217 0.025
regulation of signal transduction GO:0009966 135 0.025
nucleoside triphosphate metabolic process GO:0009141 87 0.025
regulation of apoptotic signaling pathway GO:2001233 1 0.025
cell proliferation GO:0008283 116 0.025
positive regulation of macromolecule metabolic process GO:0010604 149 0.024
negative regulation of vulval development GO:0040027 206 0.024
Worm
protein oligomerization GO:0051259 4 0.024
cellular macromolecular complex assembly GO:0034622 184 0.024
germ cell development GO:0007281 351 0.024
regulation of organelle organization GO:0033043 164 0.024
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.023
regulation of multicellular organismal development GO:2000026 317 0.023
Worm
purine nucleoside catabolic process GO:0006152 75 0.023
actomyosin structure organization GO:0031032 154 0.023
pronuclear migration GO:0035046 51 0.023
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.022
mitotic nuclear division GO:0007067 89 0.022
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.022
regulation of transcription dna templated GO:0006355 164 0.022
generation of neurons GO:0048699 235 0.022
single fertilization GO:0007338 61 0.022
rna metabolic process GO:0016070 228 0.022
localization of cell GO:0051674 313 0.022
rna localization GO:0006403 3 0.022
actin filament based process GO:0030029 191 0.021
translation GO:0006412 37 0.021
Worm
regulation of protein metabolic process GO:0051246 81 0.021
single organism organelle organization GO:1902589 501 0.021
nucleoside phosphate catabolic process GO:1901292 77 0.021
mitotic cell cycle process GO:1903047 194 0.021
cellular modified amino acid biosynthetic process GO:0042398 2 0.020
Human
system process GO:0003008 136 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.020
ribonucleotide catabolic process GO:0009261 75 0.020
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.020
cellular nitrogen compound catabolic process GO:0044270 119 0.020
purine ribonucleotide metabolic process GO:0009150 95 0.020
sexual reproduction GO:0019953 546 0.020
cellular protein localization GO:0034613 75 0.019
transcription from rna polymerase ii promoter GO:0006366 149 0.019
single organism membrane fusion GO:0044801 13 0.019
negative regulation of post embryonic development GO:0048581 208 0.019
Worm
organelle assembly GO:0070925 214 0.019
nervous system development GO:0007399 253 0.019
taxis GO:0042330 128 0.019
carbohydrate derivative catabolic process GO:1901136 82 0.018
signaling GO:0023052 401 0.018
cellular response to inorganic substance GO:0071241 3 0.018
neuromuscular junction development GO:0007528 2 0.018
coenzyme biosynthetic process GO:0009108 8 0.018
Human
defense response GO:0006952 296 0.018
female gamete generation GO:0007292 254 0.018
macromolecular complex assembly GO:0065003 193 0.018
positive regulation of cellular protein catabolic process GO:1903364 3 0.018
regulation of cytoskeleton organization GO:0051493 41 0.018
regulation of phosphorus metabolic process GO:0051174 81 0.017
proteolysis GO:0006508 61 0.017
organic cyclic compound catabolic process GO:1901361 119 0.017
regulation of rna biosynthetic process GO:2001141 165 0.017
negative regulation of signal transduction GO:0009968 60 0.017
cell part morphogenesis GO:0032990 152 0.017
regulation of nuclear division GO:0051783 115 0.017
positive regulation of cell cycle GO:0045787 55 0.017
cell type specific apoptotic process GO:0097285 4 0.017
myosin filament organization GO:0031033 138 0.017
heterocycle catabolic process GO:0046700 119 0.017
regulation of cell cycle process GO:0010564 145 0.016
positive regulation of cell migration GO:0030335 3 0.016
regulation of response to wounding GO:1903034 1 0.016
chemotaxis GO:0006935 120 0.016
response to extracellular stimulus GO:0009991 38 0.016
positive regulation of rna metabolic process GO:0051254 103 0.016
cell motility GO:0048870 313 0.016
regulation of catalytic activity GO:0050790 78 0.016
purine ribonucleoside catabolic process GO:0046130 75 0.016
nucleoside triphosphate catabolic process GO:0009143 72 0.016
alpha amino acid metabolic process GO:1901605 10 0.015
regulation of lipid metabolic process GO:0019216 4 0.015
intracellular transport GO:0046907 77 0.015
myofibril assembly GO:0030239 154 0.015
myosin filament assembly GO:0031034 138 0.015
ribosome biogenesis GO:0042254 4 0.015
carboxylic acid biosynthetic process GO:0046394 21 0.015
Human
cytokinesis GO:0000910 80 0.015
regulation of cellular ketone metabolic process GO:0010565 3 0.015
sulfur compound metabolic process GO:0006790 22 0.015
Human
post embryonic organ development GO:0048569 336 0.014
Worm
maintenance of protein location in cell GO:0032507 12 0.014
response to nutrient levels GO:0031667 35 0.014
nucleoside catabolic process GO:0009164 78 0.014
positive regulation of biosynthetic process GO:0009891 109 0.014
purine ribonucleotide catabolic process GO:0009154 75 0.014
anatomical structure formation involved in morphogenesis GO:0048646 250 0.014
striated muscle myosin thick filament assembly GO:0071688 138 0.014
positive regulation of protein metabolic process GO:0051247 45 0.014
axon development GO:0061564 163 0.014
single organism membrane organization GO:0044802 35 0.014
response to abiotic stimulus GO:0009628 152 0.014
cuticle development GO:0042335 100 0.014
regeneration GO:0031099 4 0.014
negative regulation of cell communication GO:0010648 61 0.014
positive regulation of cellular biosynthetic process GO:0031328 109 0.014
purine nucleotide catabolic process GO:0006195 75 0.013
macromolecule catabolic process GO:0009057 202 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.013
regulation of protein ubiquitination GO:0031396 3 0.013
response to starvation GO:0042594 26 0.013
phagocytosis GO:0006909 115 0.013
ribonucleoside triphosphate catabolic process GO:0009203 72 0.013
positive regulation of proteasomal protein catabolic process GO:1901800 1 0.013
synaptic growth at neuromuscular junction GO:0051124 1 0.013
oogenesis GO:0048477 229 0.013
regulation of cytoplasmic transport GO:1903649 3 0.013
sulfur amino acid metabolic process GO:0000096 4 0.012
negative regulation of response to stimulus GO:0048585 73 0.012
dna templated transcription elongation GO:0006354 1 0.012
regulation of molecular function GO:0065009 89 0.012
sister chromatid segregation GO:0000819 46 0.012
protein phosphorylation GO:0006468 85 0.012
single organism signaling GO:0044700 401 0.012
organic acid biosynthetic process GO:0016053 21 0.012
Human
negative regulation of signaling GO:0023057 61 0.012
regulation of transport GO:0051049 91 0.012
regulation of cell proliferation GO:0042127 105 0.012
membrane invagination GO:0010324 98 0.012
carbohydrate metabolic process GO:0005975 34 0.012
regulation of meiosis GO:0040020 94 0.012
protein localization to organelle GO:0033365 37 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.012
positive regulation of intracellular transport GO:0032388 2 0.012
cellular ketone metabolic process GO:0042180 14 0.012
cellular macromolecule localization GO:0070727 75 0.012
neurological system process GO:0050877 53 0.012
regulation of cellular amine metabolic process GO:0033238 0 0.012
neurotransmitter transport GO:0006836 32 0.011
protein transport GO:0015031 45 0.011
rrna processing GO:0006364 3 0.011
positive regulation of catalytic activity GO:0043085 59 0.011
rrna metabolic process GO:0016072 3 0.011
protein catabolic process GO:0030163 162 0.011
ion transport GO:0006811 113 0.011
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 1 0.011
pigmentation GO:0043473 2 0.011
inductive cell migration GO:0040039 145 0.011
cellular component assembly involved in morphogenesis GO:0010927 183 0.011
organophosphate catabolic process GO:0046434 81 0.011
cellular response to external stimulus GO:0071496 16 0.011
nucleotide catabolic process GO:0009166 77 0.011
organonitrogen compound catabolic process GO:1901565 90 0.011
glycosyl compound catabolic process GO:1901658 79 0.011
response to biotic stimulus GO:0009607 101 0.011
apical junction assembly GO:0043297 1 0.011
cofactor biosynthetic process GO:0051188 8 0.011
Human
neuron projection guidance GO:0097485 82 0.011
microtubule based process GO:0007017 182 0.011
single organism behavior GO:0044708 83 0.011
sensory organ morphogenesis GO:0090596 2 0.010
tissue development GO:0009888 112 0.010
Zebrafish
male gamete generation GO:0048232 41 0.010
guanosine containing compound metabolic process GO:1901068 49 0.010
oocyte construction GO:0007308 2 0.010
amine metabolic process GO:0009308 15 0.010
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.010

sams-4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
disease of metabolism DOID:0014667 0 0.010