Caenorhabditis elegans

2 known processes

nep-1 (CELE_ZK20.6)

Protein NEP-1

nep-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.399
post embryonic development GO:0009791 2152 0.351
embryo development ending in birth or egg hatching GO:0009792 2992 0.307
sex differentiation GO:0007548 909 0.290
Worm
single organism reproductive process GO:0044702 1196 0.266
Worm
body morphogenesis GO:0010171 620 0.262
response to chemical GO:0042221 356 0.260
locomotion GO:0040011 1634 0.236
negative regulation of vulval development GO:0040027 206 0.235
regulation of vulval development GO:0040028 248 0.232
sexual reproduction GO:0019953 546 0.231
cell development GO:0048468 696 0.229
multicellular organism reproduction GO:0032504 819 0.219
multi organism reproductive process GO:0044703 867 0.215
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.215
organ development GO:0048513 1102 0.204
Worm
gonad development GO:0008406 840 0.197
Worm
developmental process involved in reproduction GO:0003006 1165 0.197
Worm
aging GO:0007568 812 0.196
multicellular organismal aging GO:0010259 812 0.193
gene expression GO:0010467 412 0.191
regulation of multicellular organismal process GO:0051239 726 0.186
reproductive structure development GO:0048608 850 0.185
Worm
reproductive system development GO:0061458 850 0.174
Worm
regulation of developmental process GO:0050793 684 0.166
receptor mediated endocytosis GO:0006898 715 0.166
determination of adult lifespan GO:0008340 812 0.161
multicellular organismal reproductive process GO:0048609 815 0.160
positive regulation of multicellular organismal process GO:0051240 417 0.159
hermaphrodite genitalia development GO:0040035 734 0.158
Worm
molting cycle GO:0042303 281 0.156
genitalia development GO:0048806 741 0.153
Worm
vulval development GO:0040025 333 0.152
transport GO:0006810 1093 0.147
cell division GO:0051301 262 0.141
regulation of nematode larval development GO:0061062 260 0.139
cell death GO:0008219 547 0.133
cell cycle process GO:0022402 482 0.133
negative regulation of post embryonic development GO:0048581 208 0.127
regulation of gene expression GO:0010468 366 0.127
macromolecule localization GO:0033036 771 0.123
positive regulation of developmental growth GO:0048639 354 0.120
apoptotic process GO:0006915 478 0.113
post embryonic organ development GO:0048569 336 0.113
development of primary sexual characteristics GO:0045137 840 0.113
Worm
gamete generation GO:0007276 461 0.112
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.111
positive regulation of multicellular organism growth GO:0040018 352 0.110
endocytosis GO:0006897 819 0.109
vesicle mediated transport GO:0016192 852 0.106
positive regulation of developmental process GO:0051094 408 0.106
germ cell development GO:0007281 351 0.105
regulation of rna metabolic process GO:0051252 173 0.104
regulation of developmental growth GO:0048638 389 0.102
programmed cell death GO:0012501 500 0.100
oogenesis GO:0048477 229 0.099
cellular nitrogen compound biosynthetic process GO:0044271 192 0.097
regulation of multicellular organismal development GO:2000026 317 0.092
negative regulation of biological process GO:0048519 567 0.088
regulation of biological quality GO:0065008 741 0.085
death GO:0016265 547 0.085
organelle organization GO:0006996 783 0.083
single organism localization GO:1902578 518 0.083
regulation of post embryonic development GO:0048580 260 0.082
reproductive behavior GO:0019098 387 0.080
nucleobase containing compound metabolic process GO:0006139 406 0.078
regulation of multicellular organism growth GO:0040014 373 0.078
positive regulation of growth GO:0045927 369 0.077
lipid localization GO:0010876 573 0.073
maintenance of location GO:0051235 580 0.072
establishment of localization GO:0051234 1171 0.071
multi organism reproductive behavior GO:0044705 387 0.070
single organism transport GO:0044765 447 0.069
digestive system development GO:0055123 122 0.068
heterocycle biosynthetic process GO:0018130 187 0.068
female gamete generation GO:0007292 254 0.067
multicellular organism growth GO:0035264 385 0.067
regulation of rna biosynthetic process GO:2001141 165 0.066
cellular component movement GO:0006928 388 0.066
cell cycle GO:0007049 526 0.064
lipid storage GO:0019915 565 0.062
negative regulation of developmental process GO:0051093 227 0.062
single organism organelle organization GO:1902589 501 0.062
regulation of nucleic acid templated transcription GO:1903506 165 0.062
regulation of nitrogen compound metabolic process GO:0051171 222 0.061
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.061
cellular protein metabolic process GO:0044267 279 0.060
head development GO:0060322 1 0.059
rna metabolic process GO:0016070 228 0.059
rna biosynthetic process GO:0032774 169 0.059
multi multicellular organism process GO:0044706 390 0.058
negative regulation of nematode larval development GO:0061064 208 0.058
behavior GO:0007610 527 0.058
macromolecular complex subunit organization GO:0043933 320 0.057
protein metabolic process GO:0019538 422 0.057
regulation of metabolic process GO:0019222 478 0.057
developmental growth GO:0048589 412 0.056
multi organism behavior GO:0051705 389 0.055
transcription dna templated GO:0006351 168 0.054
oviposition GO:0018991 364 0.054
negative regulation of multicellular organismal process GO:0051241 236 0.054
transcription from rna polymerase ii promoter GO:0006366 149 0.054
tube development GO:0035295 126 0.053
defense response GO:0006952 296 0.052
growth GO:0040007 562 0.051
regulation of biosynthetic process GO:0009889 189 0.049
cellular macromolecule biosynthetic process GO:0034645 247 0.049
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.048
nucleic acid templated transcription GO:0097659 169 0.047
regulation of growth GO:0040008 409 0.047
regulation of macromolecule metabolic process GO:0060255 421 0.044
neuron projection development GO:0031175 187 0.043
negative regulation of cellular process GO:0048523 239 0.042
male anatomical structure morphogenesis GO:0090598 78 0.042
cellular response to topologically incorrect protein GO:0035967 76 0.042
multicellular organismal reproductive behavior GO:0033057 384 0.041
protein localization GO:0008104 205 0.041
nucleic acid metabolic process GO:0090304 299 0.041
organic substance biosynthetic process GO:1901576 323 0.038
regulation of primary metabolic process GO:0080090 292 0.038
regulation of cellular component organization GO:0051128 248 0.038
digestive tract development GO:0048565 122 0.037
endoplasmic reticulum unfolded protein response GO:0030968 66 0.036
negative regulation of gene expression GO:0010629 217 0.036
cellular component assembly GO:0022607 293 0.036
regulation of locomotion GO:0040012 161 0.036
macromolecule biosynthetic process GO:0009059 250 0.035
sensory organ morphogenesis GO:0090596 2 0.035
biosynthetic process GO:0009058 323 0.035
neuron differentiation GO:0030182 217 0.035
regulation of response to stimulus GO:0048583 243 0.034
regulation of transcription dna templated GO:0006355 164 0.034
regulation of cell cycle process GO:0010564 145 0.034
embryonic morphogenesis GO:0048598 152 0.033
cellular biosynthetic process GO:0044249 315 0.033
negative regulation of transcription dna templated GO:0045892 53 0.033
negative regulation of macromolecule metabolic process GO:0010605 229 0.032
regulation of macromolecule biosynthetic process GO:0010556 189 0.032
response to abiotic stimulus GO:0009628 152 0.032
regulation of cellular metabolic process GO:0031323 305 0.032
negative regulation of nucleic acid templated transcription GO:1903507 53 0.032
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.032
signaling GO:0023052 401 0.030
catabolic process GO:0009056 318 0.030
negative regulation of rna biosynthetic process GO:1902679 53 0.030
neuron projection guidance GO:0097485 82 0.030
cell motility GO:0048870 313 0.030
meiotic cell cycle GO:0051321 335 0.030
neurogenesis GO:0022008 236 0.030
pattern specification process GO:0007389 59 0.029
aromatic compound biosynthetic process GO:0019438 192 0.028
organic cyclic compound biosynthetic process GO:1901362 195 0.028
nervous system development GO:0007399 253 0.028
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.028
negative regulation of rna metabolic process GO:0051253 53 0.028
cellular response to unfolded protein GO:0034620 71 0.027
single organism signaling GO:0044700 401 0.027
cellular response to chemical stimulus GO:0070887 129 0.027
axon guidance GO:0007411 82 0.027
localization of cell GO:0051674 313 0.027
meiotic cell cycle process GO:1903046 170 0.027
establishment of localization in cell GO:0051649 318 0.027
meiotic nuclear division GO:0007126 300 0.027
negative regulation of cellular metabolic process GO:0031324 95 0.027
ion transport GO:0006811 113 0.027
cellular component morphogenesis GO:0032989 318 0.027
negative regulation of metabolic process GO:0009892 240 0.027
oocyte construction GO:0007308 2 0.026
cellular protein modification process GO:0006464 207 0.026
nematode male tail tip morphogenesis GO:0045138 77 0.026
cell projection organization GO:0030030 231 0.025
response to topologically incorrect protein GO:0035966 82 0.025
ribosome biogenesis GO:0042254 4 0.025
mitotic cell cycle process GO:1903047 194 0.025
cuticle development GO:0042335 100 0.025
organelle fission GO:0048285 363 0.025
response to wounding GO:0009611 4 0.025
response to endoplasmic reticulum stress GO:0034976 71 0.024
organ morphogenesis GO:0009887 67 0.024
signal transduction GO:0007165 317 0.024
negative regulation of biosynthetic process GO:0009890 65 0.023
cellular localization GO:0051641 360 0.023
macromolecule modification GO:0043412 218 0.023
regulation of signal transduction GO:0009966 135 0.023
protein modification process GO:0036211 207 0.022
oocyte axis specification GO:0007309 2 0.022
protein complex biogenesis GO:0070271 186 0.022
regulation of cell division GO:0051302 142 0.022
protein complex subunit organization GO:0071822 280 0.022
response to unfolded protein GO:0006986 71 0.021
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.021
actomyosin structure organization GO:0031032 154 0.021
negative regulation of cellular biosynthetic process GO:0031327 65 0.021
male sex differentiation GO:0046661 86 0.021
regulation of localization GO:0032879 194 0.020
collagen and cuticulin based cuticle development GO:0040002 99 0.020
neuron projection morphogenesis GO:0048812 114 0.020
actin filament based process GO:0030029 191 0.020
small molecule metabolic process GO:0044281 186 0.020
tissue development GO:0009888 112 0.020
protein complex assembly GO:0006461 186 0.020
nucleobase containing compound biosynthetic process GO:0034654 184 0.019
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.019
generation of neurons GO:0048699 235 0.019
cytoskeleton dependent cytokinesis GO:0061640 35 0.019
neuron development GO:0048666 199 0.019
muscle structure development GO:0061061 191 0.019
response to external stimulus GO:0009605 289 0.019
mitotic nuclear division GO:0007067 89 0.018
epithelial tube morphogenesis GO:0060562 1 0.018
cell migration GO:0016477 306 0.018
striated muscle cell differentiation GO:0051146 158 0.018
cellular protein localization GO:0034613 75 0.018
macromolecular complex assembly GO:0065003 193 0.018
organic substance catabolic process GO:1901575 294 0.017
cell part morphogenesis GO:0032990 152 0.017
organelle assembly GO:0070925 214 0.017
phosphate containing compound metabolic process GO:0006796 232 0.017
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.017
oocyte differentiation GO:0009994 45 0.017
muscle tissue development GO:0060537 1 0.017
organonitrogen compound metabolic process GO:1901564 151 0.016
chromosome segregation GO:0007059 180 0.016
regulation of meiosis GO:0040020 94 0.016
regulation of cellular component movement GO:0051270 62 0.016
engulfment of apoptotic cell GO:0043652 94 0.016
cell surface receptor signaling pathway GO:0007166 149 0.016
cellular macromolecular complex assembly GO:0034622 184 0.016
regulation of nuclear division GO:0051783 115 0.016
anatomical structure formation involved in morphogenesis GO:0048646 250 0.016
rna interference GO:0016246 137 0.016
regulation of cell communication GO:0010646 176 0.016
myosin filament organization GO:0031033 138 0.016
regulation of organelle organization GO:0033043 164 0.015
cell projection morphogenesis GO:0048858 148 0.015
axon development GO:0061564 163 0.015
glycosyl compound metabolic process GO:1901657 100 0.015
tube morphogenesis GO:0035239 79 0.015
cellular component biogenesis GO:0044085 297 0.015
meiotic chromosome segregation GO:0045132 139 0.015
microtubule based process GO:0007017 182 0.015
single organism behavior GO:0044708 83 0.015
developmental maturation GO:0021700 26 0.014
regulation of cellular biosynthetic process GO:0031326 189 0.014
macromolecule catabolic process GO:0009057 202 0.014
regulation of cytoplasmic transport GO:1903649 3 0.014
cation transport GO:0006812 78 0.014
regulation of meiotic cell cycle GO:0051445 136 0.014
innate immune response GO:0045087 190 0.014
cellular response to organic substance GO:0071310 119 0.014
regulation of gene expression epigenetic GO:0040029 163 0.014
cellular response to stress GO:0033554 162 0.013
er nucleus signaling pathway GO:0006984 66 0.013
positive regulation of protein transport GO:0051222 4 0.013
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.013
cell maturation GO:0048469 26 0.013
muscle cell development GO:0055001 158 0.013
taxis GO:0042330 128 0.013
gene silencing by rna GO:0031047 143 0.013
myofibril assembly GO:0030239 154 0.013
chemotaxis GO:0006935 120 0.013
cellular protein complex assembly GO:0043623 178 0.013
gene silencing GO:0016458 143 0.012
intracellular transport GO:0046907 77 0.012
cell proliferation GO:0008283 116 0.012
myosin filament assembly GO:0031034 138 0.012
posttranscriptional gene silencing by rna GO:0035194 143 0.012
organic substance transport GO:0071702 113 0.012
digestive tract morphogenesis GO:0048546 76 0.012
posttranscriptional gene silencing GO:0016441 143 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.012
immune response GO:0006955 192 0.012
cytoskeleton organization GO:0007010 339 0.012
actin cytoskeleton organization GO:0030036 184 0.012
axonogenesis GO:0007409 102 0.012
carboxylic acid metabolic process GO:0019752 34 0.012
striated muscle cell development GO:0055002 157 0.012
regulation of apoptotic signaling pathway GO:2001233 1 0.012
positive regulation of cellular process GO:0048522 332 0.011
cell morphogenesis involved in differentiation GO:0000904 112 0.011
metal ion transport GO:0030001 49 0.011
system process GO:0003008 136 0.011
carbohydrate derivative metabolic process GO:1901135 141 0.011
organic acid metabolic process GO:0006082 47 0.011
regulation of protein import into nucleus GO:0042306 3 0.011
secretion GO:0046903 147 0.011
regulation of cell proliferation GO:0042127 105 0.011
rna localization GO:0006403 3 0.011
phagocytosis GO:0006909 115 0.011
muscle cell differentiation GO:0042692 171 0.011
regulation of nucleocytoplasmic transport GO:0046822 3 0.011
cell type specific apoptotic process GO:0097285 4 0.011
protein catabolic process GO:0030163 162 0.011
membrane organization GO:0061024 135 0.011
oocyte development GO:0048599 44 0.010
olfactory behavior GO:0042048 27 0.010
response to oxygen containing compound GO:1901700 44 0.010
endosomal transport GO:0016197 26 0.010
striated muscle myosin thick filament assembly GO:0071688 138 0.010
cellular macromolecule localization GO:0070727 75 0.010
inductive cell migration GO:0040039 145 0.010
cell recognition GO:0008037 85 0.010
axis specification GO:0009798 23 0.010

nep-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.013
disease of anatomical entity DOID:7 0 0.013
hematopoietic system disease DOID:74 0 0.013