Caenorhabditis elegans

49 known processes

bmk-1 (CELE_F23B12.8)

Protein BMK-1

bmk-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.942
meiotic chromosome segregation GO:0045132 139 0.872
chromosome segregation GO:0007059 180 0.839
developmental process involved in reproduction GO:0003006 1165 0.832
gonad development GO:0008406 840 0.790
organ development GO:0048513 1102 0.671
sex differentiation GO:0007548 909 0.668
mitotic nuclear division GO:0007067 89 0.651
Human Mouse Fly
single organism reproductive process GO:0044702 1196 0.640
meiotic nuclear division GO:0007126 300 0.634
embryo development GO:0009790 3052 0.618
cell cycle GO:0007049 526 0.558
regulation of vulval development GO:0040028 248 0.534
genitalia development GO:0048806 741 0.508
hermaphrodite genitalia development GO:0040035 734 0.500
chromosome organization GO:0051276 104 0.478
organelle fission GO:0048285 363 0.461
Human Mouse Fly
vesicle mediated transport GO:0016192 852 0.418
reproductive structure development GO:0048608 850 0.405
chromosome organization involved in meiosis GO:0070192 25 0.384
attachment of spindle microtubules to kinetochore GO:0008608 8 0.380
post embryonic development GO:0009791 2152 0.377
locomotion GO:0040011 1634 0.359
catabolic process GO:0009056 318 0.355
regulation of meiosis GO:0040020 94 0.352
meiotic cell cycle GO:0051321 335 0.344
microtubule cytoskeleton organization involved in mitosis GO:1902850 12 0.337
Human
gamete generation GO:0007276 461 0.322
meiotic cell cycle process GO:1903046 170 0.311
spindle organization GO:0007051 92 0.282
regulation of cellular component organization GO:0051128 248 0.280
regulation of cell division GO:0051302 142 0.276
organelle organization GO:0006996 783 0.274
vulval development GO:0040025 333 0.261
sister chromatid segregation GO:0000819 46 0.259
reproductive system development GO:0061458 850 0.259
regulation of nuclear division GO:0051783 115 0.256
purine containing compound catabolic process GO:0072523 75 0.249
regulation of nematode larval development GO:0061062 260 0.248
development of primary sexual characteristics GO:0045137 840 0.234
cell cycle process GO:0022402 482 0.231
regulation of developmental process GO:0050793 684 0.229
regulation of meiotic cell cycle GO:0051445 136 0.218
transport GO:0006810 1093 0.215
Fly
ribonucleoside triphosphate metabolic process GO:0009199 87 0.199
negative regulation of biological process GO:0048519 567 0.194
mitotic cell cycle process GO:1903047 194 0.194
regulation of organelle organization GO:0033043 164 0.186
organic substance catabolic process GO:1901575 294 0.182
receptor mediated endocytosis GO:0006898 715 0.176
microtubule anchoring GO:0034453 8 0.176
regulation of cell cycle process GO:0010564 145 0.174
endocytosis GO:0006897 819 0.169
generation of neurons GO:0048699 235 0.168
protein catabolic process GO:0030163 162 0.166
aging GO:0007568 812 0.162
maintenance of protein location in cell GO:0032507 12 0.158
purine nucleotide catabolic process GO:0006195 75 0.157
carbohydrate derivative catabolic process GO:1901136 82 0.157
polar body extrusion after meiotic divisions GO:0040038 14 0.154
single organism organelle organization GO:1902589 501 0.146
negative regulation of vulval development GO:0040027 206 0.143
body morphogenesis GO:0010171 620 0.141
regulation of metabolic process GO:0019222 478 0.139
positive regulation of cellular process GO:0048522 332 0.138
cellular nitrogen compound catabolic process GO:0044270 119 0.135
regulation of multicellular organismal process GO:0051239 726 0.127
oviposition GO:0018991 364 0.126
histone modification GO:0016570 30 0.125
signal transduction GO:0007165 317 0.124
regulation of post embryonic development GO:0048580 260 0.124
multicellular organismal reproductive process GO:0048609 815 0.123
organonitrogen compound catabolic process GO:1901565 90 0.122
ribonucleoside catabolic process GO:0042454 77 0.121
germ cell development GO:0007281 351 0.120
cellular catabolic process GO:0044248 199 0.114
negative regulation of chromosome segregation GO:0051985 4 0.113
multicellular organismal aging GO:0010259 812 0.113
regulation of primary metabolic process GO:0080090 292 0.111
purine ribonucleoside catabolic process GO:0046130 75 0.111
purine nucleoside triphosphate metabolic process GO:0009144 87 0.109
oogenesis GO:0048477 229 0.107
glycosyl compound catabolic process GO:1901658 79 0.107
chromatin modification GO:0016568 32 0.107
programmed cell death GO:0012501 500 0.107
cell division GO:0051301 262 0.106
protein metabolic process GO:0019538 422 0.106
spindle assembly GO:0051225 8 0.105
Human
nucleoside triphosphate catabolic process GO:0009143 72 0.104
purine nucleoside triphosphate catabolic process GO:0009146 72 0.104
negative regulation of developmental process GO:0051093 227 0.104
post embryonic organ development GO:0048569 336 0.104
determination of adult lifespan GO:0008340 812 0.103
cell death GO:0008219 547 0.101
regulation of gene expression GO:0010468 366 0.101
positive regulation of multicellular organismal process GO:0051240 417 0.101
death GO:0016265 547 0.098
multicellular organismal reproductive behavior GO:0033057 384 0.097
purine nucleoside catabolic process GO:0006152 75 0.095
regulation of rna biosynthetic process GO:2001141 165 0.094
purine ribonucleoside metabolic process GO:0046128 92 0.094
sexual reproduction GO:0019953 546 0.094
ribonucleotide catabolic process GO:0009261 75 0.094
regulation of mitosis GO:0007088 18 0.093
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.093
establishment of chromosome localization GO:0051303 10 0.093
single organism signaling GO:0044700 401 0.092
single organism catabolic process GO:0044712 129 0.091
cellular component movement GO:0006928 388 0.090
Fly
regulation of macromolecule metabolic process GO:0060255 421 0.089
multicellular organism reproduction GO:0032504 819 0.089
purine ribonucleotide catabolic process GO:0009154 75 0.089
regulation of transcription dna templated GO:0006355 164 0.088
single organism localization GO:1902578 518 0.088
Fly
regulation of biological quality GO:0065008 741 0.088
organophosphate metabolic process GO:0019637 125 0.087
nucleotide catabolic process GO:0009166 77 0.085
nucleic acid templated transcription GO:0097659 169 0.085
nucleoside phosphate catabolic process GO:1901292 77 0.085
purine containing compound metabolic process GO:0072521 95 0.083
purine ribonucleotide metabolic process GO:0009150 95 0.083
establishment of localization GO:0051234 1171 0.083
Fly
purine nucleoside metabolic process GO:0042278 92 0.083
organonitrogen compound metabolic process GO:1901564 151 0.083
regulation of cellular metabolic process GO:0031323 305 0.082
microtubule based process GO:0007017 182 0.082
maintenance of protein location GO:0045185 15 0.082
aromatic compound catabolic process GO:0019439 116 0.081
macromolecule catabolic process GO:0009057 202 0.079
nucleobase containing small molecule metabolic process GO:0055086 115 0.079
glycosyl compound metabolic process GO:1901657 100 0.078
nucleoside catabolic process GO:0009164 78 0.078
cellular component biogenesis GO:0044085 297 0.078
Human Fly
regulation of multicellular organismal development GO:2000026 317 0.074
growth GO:0040007 562 0.072
rna biosynthetic process GO:0032774 169 0.072
ribonucleoside metabolic process GO:0009119 98 0.071
negative regulation of multicellular organismal process GO:0051241 236 0.071
mitotic sister chromatid segregation GO:0000070 38 0.070
small molecule metabolic process GO:0044281 186 0.069
female gamete generation GO:0007292 254 0.069
transcription from rna polymerase ii promoter GO:0006366 149 0.068
organic cyclic compound catabolic process GO:1901361 119 0.066
macromolecule localization GO:0033036 771 0.066
Fly
maintenance of location GO:0051235 580 0.064
regulation of cellular biosynthetic process GO:0031326 189 0.064
regulation of mitotic cell cycle GO:0007346 76 0.064
organophosphate catabolic process GO:0046434 81 0.063
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.063
regulation of cell proliferation GO:0042127 105 0.063
chromatin organization GO:0006325 32 0.061
ubiquitin dependent protein catabolic process GO:0006511 32 0.060
heterocycle catabolic process GO:0046700 119 0.060
carbohydrate derivative metabolic process GO:1901135 141 0.059
ribonucleoside triphosphate catabolic process GO:0009203 72 0.059
cellular biosynthetic process GO:0044249 315 0.059
phosphorus metabolic process GO:0006793 232 0.058
positive regulation of developmental process GO:0051094 408 0.058
covalent chromatin modification GO:0016569 30 0.058
positive regulation of cellular metabolic process GO:0031325 178 0.058
nucleobase containing compound catabolic process GO:0034655 114 0.057
neuron differentiation GO:0030182 217 0.056
developmental growth GO:0048589 412 0.056
regulation of growth GO:0040008 409 0.055
regulation of mitotic metaphase anaphase transition GO:0030071 5 0.055
regulation of cellular protein metabolic process GO:0032268 75 0.054
mitotic spindle organization GO:0007052 81 0.053
cell migration GO:0016477 306 0.053
kinetochore assembly GO:0051382 5 0.053
negative regulation of nematode larval development GO:0061064 208 0.053
positive regulation of metabolic process GO:0009893 187 0.052
nucleoside metabolic process GO:0009116 99 0.052
localization of cell GO:0051674 313 0.051
multicellular organism growth GO:0035264 385 0.051
metaphase anaphase transition of cell cycle GO:0044784 15 0.051
establishment of organelle localization GO:0051656 123 0.050
macromolecule biosynthetic process GO:0009059 250 0.050
cell projection organization GO:0030030 231 0.050
cellular protein metabolic process GO:0044267 279 0.049
nucleotide metabolic process GO:0009117 108 0.049
phosphate containing compound metabolic process GO:0006796 232 0.048
cellular localization GO:0051641 360 0.048
Fly
nervous system development GO:0007399 253 0.048
Fly
gene expression GO:0010467 412 0.048
signaling GO:0023052 401 0.047
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.047
protein modification process GO:0036211 207 0.047
cell development GO:0048468 696 0.047
positive regulation of multicellular organism growth GO:0040018 352 0.047
regulation of multicellular organism growth GO:0040014 373 0.046
macromolecule modification GO:0043412 218 0.046
protein complex subunit organization GO:0071822 280 0.046
multi organism reproductive process GO:0044703 867 0.046
nucleoside phosphate metabolic process GO:0006753 108 0.045
nucleoside triphosphate metabolic process GO:0009141 87 0.045
lipid storage GO:0019915 565 0.044
regulation of nucleic acid templated transcription GO:1903506 165 0.043
negative regulation of cell cycle GO:0045786 53 0.043
negative regulation of cellular process GO:0048523 239 0.043
regulation of cytoskeleton organization GO:0051493 41 0.042
chromosome localization GO:0050000 10 0.042
positive regulation of signal transduction GO:0009967 40 0.042
chromosome condensation GO:0030261 6 0.042
spindle assembly involved in mitosis GO:0090307 6 0.041
Human
cellular nitrogen compound biosynthetic process GO:0044271 192 0.040
positive regulation of growth GO:0045927 369 0.040
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.040
heterocycle biosynthetic process GO:0018130 187 0.040
modification dependent protein catabolic process GO:0019941 32 0.040
regulation of developmental growth GO:0048638 389 0.039
nucleobase containing compound biosynthetic process GO:0034654 184 0.039
oocyte differentiation GO:0009994 45 0.039
meiotic sister chromatid segregation GO:0045144 15 0.039
small gtpase mediated signal transduction GO:0007264 32 0.038
multi organism reproductive behavior GO:0044705 387 0.038
cellular protein modification process GO:0006464 207 0.038
negative regulation of gene expression GO:0010629 217 0.038
organelle localization GO:0051640 127 0.037
ribonucleotide metabolic process GO:0009259 99 0.037
lipid localization GO:0010876 573 0.037
negative regulation of mitotic metaphase anaphase transition GO:0045841 4 0.037
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.036
neuron projection development GO:0031175 187 0.036
regulation of macromolecule biosynthetic process GO:0010556 189 0.036
interspecies interaction between organisms GO:0044419 5 0.036
negative regulation of gene expression epigenetic GO:0045814 2 0.036
multi multicellular organism process GO:0044706 390 0.036
protein complex assembly GO:0006461 186 0.035
Human Fly
regulation of protein metabolic process GO:0051246 81 0.034
cell morphogenesis GO:0000902 163 0.034
attachment of mitotic spindle microtubules to kinetochore GO:0051315 6 0.033
male gamete generation GO:0048232 41 0.033
regulation of cell communication GO:0010646 176 0.033
positive regulation of nematode larval development GO:0061063 54 0.033
regulation of mitotic spindle organization GO:0060236 3 0.033
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.032
regulation of catalytic activity GO:0050790 78 0.032
molting cycle GO:0042303 281 0.032
cytoskeleton organization GO:0007010 339 0.032
negative regulation of nucleic acid templated transcription GO:1903507 53 0.032
positive regulation of cell communication GO:0010647 69 0.032
multi organism behavior GO:0051705 389 0.032
male sex differentiation GO:0046661 86 0.031
negative regulation of cellular component organization GO:0051129 33 0.031
protein complex biogenesis GO:0070271 186 0.031
Human Fly
axon development GO:0061564 163 0.031
neuron development GO:0048666 199 0.031
ras protein signal transduction GO:0007265 31 0.031
aromatic compound biosynthetic process GO:0019438 192 0.030
nucleobase containing compound metabolic process GO:0006139 406 0.030
spindle checkpoint GO:0031577 4 0.029
regulation of cell cycle GO:0051726 194 0.029
regulation of chromosome organization GO:0033044 20 0.028
purine nucleotide metabolic process GO:0006163 95 0.028
regulation of mitotic sister chromatid segregation GO:0033047 16 0.028
cell motility GO:0048870 313 0.028
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.028
organic cyclic compound biosynthetic process GO:1901362 195 0.028
regulation of nitrogen compound metabolic process GO:0051171 222 0.028
proteolysis involved in cellular protein catabolic process GO:0051603 32 0.027
behavior GO:0007610 527 0.027
negative regulation of cellular catabolic process GO:0031330 9 0.027
dna metabolic process GO:0006259 74 0.027
negative regulation of cellular metabolic process GO:0031324 95 0.027
meiosis ii GO:0007135 16 0.026
regulation of microtubule cytoskeleton organization GO:0070507 21 0.026
single organism transport GO:0044765 447 0.026
Fly
ribose phosphate metabolic process GO:0019693 99 0.026
cellular macromolecule catabolic process GO:0044265 73 0.026
positive regulation of signaling GO:0023056 66 0.026
positive regulation of developmental growth GO:0048639 354 0.026
cellular protein catabolic process GO:0044257 37 0.025
cell projection morphogenesis GO:0048858 148 0.025
maintenance of location in cell GO:0051651 12 0.025
regulation of localization GO:0032879 194 0.025
cellular macromolecule biosynthetic process GO:0034645 247 0.025
response to chemical GO:0042221 356 0.024
nucleic acid metabolic process GO:0090304 299 0.024
negative regulation of post embryonic development GO:0048581 208 0.024
reproductive behavior GO:0019098 387 0.024
ribonucleoside monophosphate metabolic process GO:0009161 45 0.023
macromolecular complex subunit organization GO:0043933 320 0.023
regulation of chromosome segregation GO:0051983 20 0.023
organic acid metabolic process GO:0006082 47 0.023
meiosis i GO:0007127 19 0.023
cell proliferation GO:0008283 116 0.023
regulation of cellular catabolic process GO:0031329 51 0.022
negative regulation of cellular protein catabolic process GO:1903363 4 0.022
positive regulation of phosphate metabolic process GO:0045937 56 0.022
peptidyl amino acid modification GO:0018193 58 0.022
cell part morphogenesis GO:0032990 152 0.021
oocyte construction GO:0007308 2 0.020
negative regulation of organelle organization GO:0010639 20 0.020
cellular response to stress GO:0033554 162 0.020
modification dependent macromolecule catabolic process GO:0043632 32 0.020
membrane invagination GO:0010324 98 0.020
regulation of phosphate metabolic process GO:0019220 81 0.020
single fertilization GO:0007338 61 0.020
positive regulation of post embryonic development GO:0048582 54 0.020
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 20 0.019
neurogenesis GO:0022008 236 0.019
Fly
negative regulation of metabolic process GO:0009892 240 0.019
biosynthetic process GO:0009058 323 0.019
mitotic metaphase plate congression GO:0007080 5 0.019
regulation of catabolic process GO:0009894 57 0.019
transcription dna templated GO:0006351 168 0.019
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.019
defense response GO:0006952 296 0.019
membrane organization GO:0061024 135 0.019
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.018
negative regulation of macromolecule metabolic process GO:0010605 229 0.018
cell fate commitment GO:0045165 139 0.018
mitotic spindle checkpoint GO:0071174 4 0.018
cellular protein localization GO:0034613 75 0.018
negative regulation of sister chromatid segregation GO:0033046 4 0.018
organelle assembly GO:0070925 214 0.018
Human
mitotic sister chromatid separation GO:0051306 13 0.017
regulation of rna metabolic process GO:0051252 173 0.017
cellular component morphogenesis GO:0032989 318 0.017
intracellular signal transduction GO:0035556 96 0.017
negative regulation of mitotic sister chromatid segregation GO:0033048 4 0.017
microtubule polymerization or depolymerization GO:0031109 22 0.017
Fly
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.017
phosphorylation GO:0016310 116 0.017
head development GO:0060322 1 0.017
cellular macromolecule localization GO:0070727 75 0.017
metaphase plate congression GO:0051310 5 0.017
positive regulation of mitotic sister chromatid separation GO:1901970 1 0.016
cellular response to organic substance GO:0071310 119 0.016
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 4 0.016
phagocytosis GO:0006909 115 0.016
regulation of nucleocytoplasmic transport GO:0046822 3 0.016
regulation of sister chromatid segregation GO:0033045 16 0.015
protein localization GO:0008104 205 0.015
Fly
kinetochore organization GO:0051383 7 0.015
proteolysis GO:0006508 61 0.015
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 5 0.015
positive regulation of vulval development GO:0040026 52 0.015
positive regulation of transcription dna templated GO:0045893 102 0.015
regulation of protein catabolic process GO:0042176 13 0.015
proteasomal protein catabolic process GO:0010498 20 0.015
nucleoside monophosphate metabolic process GO:0009123 46 0.015
neuron recognition GO:0008038 83 0.015
regulation of attachment of spindle microtubules to kinetochore GO:0051988 2 0.014
regulation of cellular ketone metabolic process GO:0010565 3 0.014
negative regulation of cellular biosynthetic process GO:0031327 65 0.014
negative regulation of rna biosynthetic process GO:1902679 53 0.014
neuron projection morphogenesis GO:0048812 114 0.014
regulation of microtubule based process GO:0032886 21 0.014
nucleus organization GO:0006997 38 0.014
cuticle development GO:0042335 100 0.014
dna packaging GO:0006323 7 0.014
assembly of actomyosin apparatus involved in cytokinesis GO:0000912 1 0.014
chromatin remodeling GO:0006338 2 0.014
negative regulation of proteasomal protein catabolic process GO:1901799 4 0.014
positive regulation of phosphorylation GO:0042327 27 0.013
metaphase anaphase transition of mitotic cell cycle GO:0007091 10 0.013
oocyte axis specification GO:0007309 2 0.013
apoptotic process GO:0006915 478 0.013
oxoacid metabolic process GO:0043436 47 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.013
regulation of purine nucleotide catabolic process GO:0033121 35 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.013
response to external stimulus GO:0009605 289 0.013
organic substance biosynthetic process GO:1901576 323 0.013
spermatogenesis GO:0007283 41 0.013
microtubule based movement GO:0007018 33 0.013
Fly
positive regulation of phosphorus metabolic process GO:0010562 56 0.013
inductive cell migration GO:0040039 145 0.013
oocyte development GO:0048599 44 0.013
positive regulation of intracellular signal transduction GO:1902533 24 0.013
protein localization to organelle GO:0033365 37 0.012
cellular ketone metabolic process GO:0042180 14 0.012
dna duplex unwinding GO:0032508 3 0.012
axonogenesis GO:0007409 102 0.012
atp catabolic process GO:0006200 27 0.012
regulation of cellular amine metabolic process GO:0033238 0 0.012
regulation of nervous system development GO:0051960 41 0.012
cellular macromolecular complex assembly GO:0034622 184 0.012
regulation of phosphorus metabolic process GO:0051174 81 0.012
cellular amine metabolic process GO:0044106 15 0.012
regulation of protein localization GO:0032880 50 0.012
negative regulation of rna metabolic process GO:0051253 53 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
atp metabolic process GO:0046034 42 0.012
reciprocal meiotic recombination GO:0007131 11 0.012
dna conformation change GO:0071103 11 0.012
positive regulation of protein metabolic process GO:0051247 45 0.012
carboxylic acid metabolic process GO:0019752 34 0.012
phagocytosis engulfment GO:0006911 98 0.011
collagen and cuticulin based cuticle development GO:0040002 99 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.011
negative regulation of mitosis GO:0045839 4 0.011
regulation of signal transduction GO:0009966 135 0.011
purine nucleoside monophosphate catabolic process GO:0009128 28 0.011
mitotic spindle assembly checkpoint GO:0007094 4 0.011
regulation of epithelial cell differentiation GO:0030856 4 0.011
protein oligomerization GO:0051259 4 0.011
Fly
positive regulation of protein modification process GO:0031401 29 0.011
cytokinetic process GO:0032506 10 0.011
establishment or maintenance of cell polarity GO:0007163 63 0.011
response to abiotic stimulus GO:0009628 152 0.011
negative regulation of transcription dna templated GO:0045892 53 0.011
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 4 0.011
negative regulation of biosynthetic process GO:0009890 65 0.011
establishment of localization in cell GO:0051649 318 0.011
Fly
regulation of apoptotic signaling pathway GO:2001233 1 0.011
male anatomical structure morphogenesis GO:0090598 78 0.010
positive regulation of chromosome organization GO:2001252 2 0.010
positive regulation of intracellular protein transport GO:0090316 2 0.010
purine nucleoside monophosphate metabolic process GO:0009126 43 0.010
axon guidance GO:0007411 82 0.010
chemotaxis GO:0006935 120 0.010
cell morphogenesis involved in differentiation GO:0000904 112 0.010

bmk-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.036
disease of cellular proliferation DOID:14566 0 0.015
nervous system disease DOID:863 0 0.011