Caenorhabditis elegans

91 known processes

mes-4 (CELE_Y2H9A.1)

Protein MES-4

mes-4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.910
embryo development ending in birth or egg hatching GO:0009792 2992 0.891
reproductive system development GO:0061458 850 0.871
developmental process involved in reproduction GO:0003006 1165 0.863
single organism reproductive process GO:0044702 1196 0.835
genitalia development GO:0048806 741 0.820
post embryonic development GO:0009791 2152 0.811
organ development GO:0048513 1102 0.784
multicellular organism reproduction GO:0032504 819 0.779
locomotion GO:0040011 1634 0.757
regulation of nematode larval development GO:0061062 260 0.752
regulation of vulval development GO:0040028 248 0.716
cellular biosynthetic process GO:0044249 315 0.685
meiotic cell cycle process GO:1903046 170 0.656
gonad development GO:0008406 840 0.648
cell cycle process GO:0022402 482 0.637
meiotic nuclear division GO:0007126 300 0.611
growth GO:0040007 562 0.610
single organism organelle organization GO:1902589 501 0.605
multicellular organismal reproductive process GO:0048609 815 0.605
regulation of nitrogen compound metabolic process GO:0051171 222 0.589
negative regulation of vulval development GO:0040027 206 0.581
regulation of multicellular organismal process GO:0051239 726 0.576
cell fate commitment GO:0045165 139 0.563
meiotic chromosome segregation GO:0045132 139 0.546
regulation of developmental process GO:0050793 684 0.536
reproductive structure development GO:0048608 850 0.531
gamete generation GO:0007276 461 0.528
meiotic cell cycle GO:0051321 335 0.514
transcription dna templated GO:0006351 168 0.508
regulation of transcription dna templated GO:0006355 164 0.471
biosynthetic process GO:0009058 323 0.468
nucleic acid metabolic process GO:0090304 299 0.465
cellular macromolecule biosynthetic process GO:0034645 247 0.462
sex differentiation GO:0007548 909 0.461
negative regulation of multicellular organismal process GO:0051241 236 0.459
regulation of macromolecule metabolic process GO:0060255 421 0.457
sexual reproduction GO:0019953 546 0.449
negative regulation of developmental process GO:0051093 227 0.449
regulation of biosynthetic process GO:0009889 189 0.447
vulval development GO:0040025 333 0.415
negative regulation of cellular process GO:0048523 239 0.413
cellular response to stress GO:0033554 162 0.408
regulation of cellular metabolic process GO:0031323 305 0.408
establishment of localization GO:0051234 1171 0.406
negative regulation of nucleic acid templated transcription GO:1903507 53 0.394
gene expression GO:0010467 412 0.390
negative regulation of biosynthetic process GO:0009890 65 0.382
regulation of nucleic acid templated transcription GO:1903506 165 0.381
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.380
programmed cell death GO:0012501 500 0.380
regulation of metabolic process GO:0019222 478 0.362
regulation of cellular biosynthetic process GO:0031326 189 0.360
rna metabolic process GO:0016070 228 0.353
multicellular organismal aging GO:0010259 812 0.352
apoptotic process GO:0006915 478 0.341
heterocycle biosynthetic process GO:0018130 187 0.318
neurogenesis GO:0022008 236 0.317
female gamete generation GO:0007292 254 0.313
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.312
hermaphrodite genitalia development GO:0040035 734 0.310
organic substance biosynthetic process GO:1901576 323 0.300
nucleobase containing compound metabolic process GO:0006139 406 0.297
macromolecule biosynthetic process GO:0009059 250 0.295
negative regulation of biological process GO:0048519 567 0.281
dna metabolic process GO:0006259 74 0.279
multicellular organismal reproductive behavior GO:0033057 384 0.273
negative regulation of nematode larval development GO:0061064 208 0.272
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.271
cellular nitrogen compound biosynthetic process GO:0044271 192 0.270
mitotic cell cycle process GO:1903047 194 0.266
positive regulation of macromolecule metabolic process GO:0010604 149 0.263
organelle fission GO:0048285 363 0.262
regulation of primary metabolic process GO:0080090 292 0.261
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.259
negative regulation of post embryonic development GO:0048581 208 0.257
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.257
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.255
cell death GO:0008219 547 0.253
post embryonic organ development GO:0048569 336 0.253
oviposition GO:0018991 364 0.251
chromosome segregation GO:0007059 180 0.250
regulation of rna metabolic process GO:0051252 173 0.250
nucleic acid templated transcription GO:0097659 169 0.248
body morphogenesis GO:0010171 620 0.243
cell cycle GO:0007049 526 0.242
death GO:0016265 547 0.240
nucleobase containing compound biosynthetic process GO:0034654 184 0.238
determination of adult lifespan GO:0008340 812 0.238
regulation of multicellular organismal development GO:2000026 317 0.237
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.234
response to abiotic stimulus GO:0009628 152 0.232
germ cell development GO:0007281 351 0.224
endocytosis GO:0006897 819 0.223
signaling GO:0023052 401 0.202
regulation of post embryonic development GO:0048580 260 0.201
multi organism reproductive process GO:0044703 867 0.201
rna biosynthetic process GO:0032774 169 0.201
negative regulation of cellular biosynthetic process GO:0031327 65 0.198
transcription from rna polymerase ii promoter GO:0006366 149 0.193
cellular protein modification process GO:0006464 207 0.184
regulation of developmental growth GO:0048638 389 0.184
oogenesis GO:0048477 229 0.183
positive regulation of cellular process GO:0048522 332 0.183
macromolecule localization GO:0033036 771 0.182
single organism localization GO:1902578 518 0.180
regulation of rna biosynthetic process GO:2001141 165 0.177
developmental growth GO:0048589 412 0.177
positive regulation of developmental process GO:0051094 408 0.177
epithelium development GO:0060429 68 0.176
response to chemical GO:0042221 356 0.172
mitotic nuclear division GO:0007067 89 0.172
negative regulation of rna metabolic process GO:0051253 53 0.172
vesicle mediated transport GO:0016192 852 0.169
regulation of gene expression GO:0010468 366 0.166
negative regulation of transcription dna templated GO:0045892 53 0.165
development of primary sexual characteristics GO:0045137 840 0.164
negative regulation of rna biosynthetic process GO:1902679 53 0.161
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.160
organelle organization GO:0006996 783 0.159
single organism signaling GO:0044700 401 0.149
regulation of macromolecule biosynthetic process GO:0010556 189 0.149
behavior GO:0007610 527 0.149
negative regulation of cellular metabolic process GO:0031324 95 0.148
cellular localization GO:0051641 360 0.148
macromolecule modification GO:0043412 218 0.146
aging GO:0007568 812 0.142
chromosome organization GO:0051276 104 0.135
multi multicellular organism process GO:0044706 390 0.126
multi organism reproductive behavior GO:0044705 387 0.125
negative regulation of metabolic process GO:0009892 240 0.122
aromatic compound biosynthetic process GO:0019438 192 0.121
response to external stimulus GO:0009605 289 0.120
tissue development GO:0009888 112 0.119
regulation of multicellular organism growth GO:0040014 373 0.116
enzyme linked receptor protein signaling pathway GO:0007167 50 0.115
positive regulation of developmental growth GO:0048639 354 0.115
positive regulation of cellular metabolic process GO:0031325 178 0.114
protein metabolic process GO:0019538 422 0.113
cellular protein metabolic process GO:0044267 279 0.113
multicellular organism growth GO:0035264 385 0.111
regulation of growth GO:0040008 409 0.111
phagocytosis GO:0006909 115 0.110
positive regulation of multicellular organismal process GO:0051240 417 0.108
positive regulation of rna metabolic process GO:0051254 103 0.107
positive regulation of growth GO:0045927 369 0.106
regulation of phosphate metabolic process GO:0019220 81 0.104
spindle organization GO:0007051 92 0.103
signal transduction GO:0007165 317 0.102
protein phosphorylation GO:0006468 85 0.100
reproductive behavior GO:0019098 387 0.099
multi organism behavior GO:0051705 389 0.096
cell division GO:0051301 262 0.095
generation of neurons GO:0048699 235 0.095
regulation of mitotic cell cycle GO:0007346 76 0.094
cell development GO:0048468 696 0.093
negative regulation of cell cycle GO:0045786 53 0.092
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.090
transport GO:0006810 1093 0.090
negative regulation of gene expression GO:0010629 217 0.085
regulation of cell cycle process GO:0010564 145 0.085
chromatin modification GO:0016568 32 0.084
defense response GO:0006952 296 0.084
protein modification process GO:0036211 207 0.083
cell motility GO:0048870 313 0.083
nervous system development GO:0007399 253 0.082
positive regulation of metabolic process GO:0009893 187 0.081
negative regulation of macromolecule metabolic process GO:0010605 229 0.080
single organism transport GO:0044765 447 0.077
macromolecular complex subunit organization GO:0043933 320 0.077
digestive tract development GO:0048565 122 0.077
positive regulation of nematode larval development GO:0061063 54 0.077
cell cell signaling GO:0007267 118 0.076
receptor mediated endocytosis GO:0006898 715 0.076
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.075
regulation of cell cycle GO:0051726 194 0.074
phosphorylation GO:0016310 116 0.074
regulation of biological quality GO:0065008 741 0.072
regulation of gene expression epigenetic GO:0040029 163 0.072
mitotic sister chromatid segregation GO:0000070 38 0.071
sister chromatid segregation GO:0000819 46 0.071
lipid storage GO:0019915 565 0.070
neuron development GO:0048666 199 0.070
covalent chromatin modification GO:0016569 30 0.069
maintenance of location GO:0051235 580 0.068
cell part morphogenesis GO:0032990 152 0.067
localization of cell GO:0051674 313 0.066
cellular response to dna damage stimulus GO:0006974 41 0.065
digestive system development GO:0055123 122 0.065
neuron projection development GO:0031175 187 0.065
positive regulation of gene expression GO:0010628 112 0.064
organic cyclic compound biosynthetic process GO:1901362 195 0.063
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.063
lipid localization GO:0010876 573 0.061
macromolecule catabolic process GO:0009057 202 0.060
cell projection organization GO:0030030 231 0.059
positive regulation of multicellular organism growth GO:0040018 352 0.057
cellular component movement GO:0006928 388 0.056
catabolic process GO:0009056 318 0.055
response to organic substance GO:0010033 131 0.055
anatomical structure formation involved in morphogenesis GO:0048646 250 0.055
organic substance catabolic process GO:1901575 294 0.054
regulation of organelle organization GO:0033043 164 0.053
negative regulation of gene expression epigenetic GO:0045814 2 0.052
positive regulation of nucleic acid templated transcription GO:1903508 102 0.050
system process GO:0003008 136 0.049
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.049
dna repair GO:0006281 23 0.047
digestive tract morphogenesis GO:0048546 76 0.047
chromosome organization involved in meiosis GO:0070192 25 0.046
oocyte development GO:0048599 44 0.046
neuron differentiation GO:0030182 217 0.045
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.045
cellular component morphogenesis GO:0032989 318 0.045
chromatin organization GO:0006325 32 0.044
regulation of signaling GO:0023051 172 0.044
neuroblast proliferation GO:0007405 9 0.043
asymmetric neuroblast division GO:0055059 8 0.043
establishment of localization in cell GO:0051649 318 0.042
cell morphogenesis GO:0000902 163 0.042
apoptotic cell clearance GO:0043277 111 0.041
regulation of locomotion GO:0040012 161 0.040
cell migration GO:0016477 306 0.040
regulation of organ morphogenesis GO:2000027 4 0.039
regulation of cellular component organization GO:0051128 248 0.039
positive regulation of rna biosynthetic process GO:1902680 102 0.039
positive regulation of biosynthetic process GO:0009891 109 0.038
regulation of signal transduction GO:0009966 135 0.038
cellular component assembly GO:0022607 293 0.038
dna geometric change GO:0032392 3 0.038
phagocytosis engulfment GO:0006911 98 0.038
stem cell proliferation GO:0072089 9 0.037
dendrite development GO:0016358 42 0.037
phosphorus metabolic process GO:0006793 232 0.037
cellular protein complex assembly GO:0043623 178 0.037
cell surface receptor signaling pathway GO:0007166 149 0.035
oocyte differentiation GO:0009994 45 0.035
regulation of meiotic cell cycle GO:0051445 136 0.035
cell maturation GO:0048469 26 0.035
regulation of catalytic activity GO:0050790 78 0.035
organelle localization GO:0051640 127 0.034
axon development GO:0061564 163 0.034
mitotic spindle organization GO:0007052 81 0.034
cell morphogenesis involved in differentiation GO:0000904 112 0.033
histone modification GO:0016570 30 0.033
tube development GO:0035295 126 0.033
dauer larval development GO:0040024 92 0.032
regulation of meiosis GO:0040020 94 0.031
establishment of organelle localization GO:0051656 123 0.031
positive regulation of cellular biosynthetic process GO:0031328 109 0.031
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.030
gene silencing GO:0016458 143 0.030
phosphate containing compound metabolic process GO:0006796 232 0.030
response to temperature stimulus GO:0009266 66 0.030
neural precursor cell proliferation GO:0061351 9 0.030
neuroblast division GO:0055057 9 0.030
regulation of behavior GO:0050795 97 0.030
positive regulation of transcription dna templated GO:0045893 102 0.029
microtubule based process GO:0007017 182 0.029
regulation of molecular function GO:0065009 89 0.029
regulation of intracellular signal transduction GO:1902531 77 0.028
cytoskeleton organization GO:0007010 339 0.028
protein localization GO:0008104 205 0.028
pattern specification process GO:0007389 59 0.028
organonitrogen compound metabolic process GO:1901564 151 0.028
regulation of cell differentiation GO:0045595 81 0.027
regulation of cell communication GO:0010646 176 0.026
membrane invagination GO:0010324 98 0.026
meiosis i GO:0007127 19 0.026
negative regulation of response to stimulus GO:0048585 73 0.026
cellular response to organic substance GO:0071310 119 0.026
response to external biotic stimulus GO:0043207 101 0.025
negative regulation of mitotic cell cycle GO:0045930 42 0.025
asymmetric stem cell division GO:0098722 8 0.025
small gtpase mediated signal transduction GO:0007264 32 0.025
regulation of phosphorus metabolic process GO:0051174 81 0.025
fertilization GO:0009566 63 0.025
cell proliferation GO:0008283 116 0.024
protein catabolic process GO:0030163 162 0.023
embryonic morphogenesis GO:0048598 152 0.023
regulation of synaptic plasticity GO:0048167 1 0.023
regulation of cell morphogenesis GO:0022604 40 0.023
negative regulation of neurogenesis GO:0050768 4 0.023
cellular catabolic process GO:0044248 199 0.022
oocyte construction GO:0007308 2 0.022
protein complex biogenesis GO:0070271 186 0.022
molting cycle GO:0042303 281 0.022
organelle assembly GO:0070925 214 0.022
regulation of phosphorylation GO:0042325 45 0.021
cell substrate adhesion GO:0031589 1 0.021
regulation of cellular ketone metabolic process GO:0010565 3 0.021
response to bacterium GO:0009617 86 0.021
tube morphogenesis GO:0035239 79 0.021
nucleobase containing compound catabolic process GO:0034655 114 0.020
double strand break repair GO:0006302 5 0.020
single organism biosynthetic process GO:0044711 91 0.019
regulation of neurogenesis GO:0050767 40 0.019
neuromuscular junction development GO:0007528 2 0.019
cellular macromolecule localization GO:0070727 75 0.019
gene silencing by rna GO:0031047 143 0.019
positive regulation of post embryonic development GO:0048582 54 0.019
engulfment of apoptotic cell GO:0043652 94 0.019
dna recombination GO:0006310 19 0.019
inductive cell migration GO:0040039 145 0.019
oxoacid metabolic process GO:0043436 47 0.018
regulation of cell development GO:0060284 49 0.018
cellular macromolecular complex assembly GO:0034622 184 0.018
somatic stem cell division GO:0048103 9 0.018
cellular response to chemical stimulus GO:0070887 129 0.018
organic acid metabolic process GO:0006082 47 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
small molecule metabolic process GO:0044281 186 0.017
neurological system process GO:0050877 53 0.017
regulation of cell division GO:0051302 142 0.017
immune response GO:0006955 192 0.017
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.017
regulation of response to stimulus GO:0048583 243 0.017
protein complex subunit organization GO:0071822 280 0.017
defense response to other organism GO:0098542 100 0.017
cellular ketone metabolic process GO:0042180 14 0.017
regulation of localization GO:0032879 194 0.016
positive regulation of catalytic activity GO:0043085 59 0.016
positive regulation of vulval development GO:0040026 52 0.016
positive regulation of cell cycle GO:0045787 55 0.016
cellular protein localization GO:0034613 75 0.016
response to biotic stimulus GO:0009607 101 0.016
head development GO:0060322 1 0.016
intracellular signal transduction GO:0035556 96 0.016
dna duplex unwinding GO:0032508 3 0.016
gastrulation GO:0007369 58 0.016
defense response to bacterium GO:0042742 86 0.015
positive regulation of response to stimulus GO:0048584 55 0.015
cytokinesis GO:0000910 80 0.015
negative regulation of signaling GO:0023057 61 0.015
response to other organism GO:0051707 101 0.015
regulation of cytoplasmic transport GO:1903649 3 0.015
single organism behavior GO:0044708 83 0.015
posttranscriptional regulation of gene expression GO:0010608 166 0.014
organ morphogenesis GO:0009887 67 0.014
striated muscle myosin thick filament assembly GO:0071688 138 0.014
carbohydrate derivative metabolic process GO:1901135 141 0.014
positive regulation of cell projection organization GO:0031346 4 0.014
regulation of cell proliferation GO:0042127 105 0.014
protein complex assembly GO:0006461 186 0.014
regulation of cellular amine metabolic process GO:0033238 0 0.014
negative regulation of cell communication GO:0010648 61 0.014
secretion GO:0046903 147 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 34 0.014
peptidyl amino acid modification GO:0018193 58 0.014
sensory organ morphogenesis GO:0090596 2 0.014
amine metabolic process GO:0009308 15 0.014
posttranscriptional gene silencing GO:0016441 143 0.013
cell cycle dna replication GO:0044786 3 0.013
cellular response to abiotic stimulus GO:0071214 4 0.013
chemotaxis GO:0006935 120 0.013
negative regulation of signal transduction GO:0009968 60 0.013
regulation of protein serine threonine kinase activity GO:0071900 18 0.013
neuronal stem cell division GO:0036445 9 0.013
organonitrogen compound catabolic process GO:1901565 90 0.013
regulation of protein stability GO:0031647 3 0.013
response to wounding GO:0009611 4 0.013
axon guidance GO:0007411 82 0.013
innate immune response GO:0045087 190 0.012
macromolecular complex assembly GO:0065003 193 0.012
regulation of cell projection organization GO:0031344 38 0.012
regulation of nucleocytoplasmic transport GO:0046822 3 0.012
purine ribonucleoside catabolic process GO:0046130 75 0.012
positive regulation of molecular function GO:0044093 61 0.012
epithelial cell proliferation GO:0050673 1 0.012
internal peptidyl lysine acetylation GO:0018393 3 0.012
oocyte axis specification GO:0007309 2 0.012
cellular response to endogenous stimulus GO:0071495 32 0.012
regulation of protein kinase activity GO:0045859 28 0.011
single organism catabolic process GO:0044712 129 0.011
regulation of dna metabolic process GO:0051052 14 0.011
purine ribonucleotide catabolic process GO:0009154 75 0.011
mrna metabolic process GO:0016071 31 0.011
collagen and cuticulin based cuticle development GO:0040002 99 0.011
pharyngeal pumping GO:0043050 58 0.011
regulation of epithelial cell proliferation GO:0050678 1 0.011
regulation of epithelial cell differentiation GO:0030856 4 0.011
feeding behavior GO:0007631 70 0.011
ion transport GO:0006811 113 0.011
spermatogenesis GO:0007283 41 0.011
regulation of protein metabolic process GO:0051246 81 0.011
response to oxygen containing compound GO:1901700 44 0.011
taxis GO:0042330 128 0.011
single organism carbohydrate metabolic process GO:0044723 29 0.011
membrane organization GO:0061024 135 0.011
establishment of mitotic spindle localization GO:0040001 41 0.011
eating behavior GO:0042755 59 0.011
learning or memory GO:0007611 27 0.010
protein polymerization GO:0051258 26 0.010
organic substance transport GO:0071702 113 0.010
regulation of transferase activity GO:0051338 31 0.010

mes-4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.028
cancer DOID:162 0 0.023
disease of cellular proliferation DOID:14566 0 0.023
organ system cancer DOID:0050686 0 0.023
large intestine cancer DOID:5672 0 0.011
gastrointestinal system cancer DOID:3119 0 0.011
intestinal cancer DOID:10155 0 0.011