Caenorhabditis elegans

17 known processes

lsy-22 (CELE_F27D4.2)

Protein LSY-22

lsy-22 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.948
embryo development ending in birth or egg hatching GO:0009792 2992 0.913
post embryonic development GO:0009791 2152 0.876
positive regulation of cellular process GO:0048522 332 0.677
establishment of localization GO:0051234 1171 0.579
receptor mediated endocytosis GO:0006898 715 0.568
protein metabolic process GO:0019538 422 0.567
regulation of cellular biosynthetic process GO:0031326 189 0.567
reproductive structure development GO:0048608 850 0.545
vesicle mediated transport GO:0016192 852 0.539
single organism organelle organization GO:1902589 501 0.521
reproductive system development GO:0061458 850 0.512
regulation of gene expression GO:0010468 366 0.508
endocytosis GO:0006897 819 0.497
regulation of macromolecule metabolic process GO:0060255 421 0.490
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.490
cellular protein metabolic process GO:0044267 279 0.439
cell cycle process GO:0022402 482 0.436
hermaphrodite genitalia development GO:0040035 734 0.434
sex differentiation GO:0007548 909 0.421
multicellular organism reproduction GO:0032504 819 0.421
multicellular organismal reproductive process GO:0048609 815 0.416
meiotic cell cycle GO:0051321 335 0.412
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.397
chromosome segregation GO:0007059 180 0.394
development of primary sexual characteristics GO:0045137 840 0.381
oviposition GO:0018991 364 0.380
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.372
single organism reproductive process GO:0044702 1196 0.371
organ development GO:0048513 1102 0.368
body morphogenesis GO:0010171 620 0.368
regulation of cell differentiation GO:0045595 81 0.366
genitalia development GO:0048806 741 0.348
determination of adult lifespan GO:0008340 812 0.348
negative regulation of gene expression GO:0010629 217 0.337
regulation of metabolic process GO:0019222 478 0.335
regulation of developmental process GO:0050793 684 0.334
rna metabolic process GO:0016070 228 0.332
sexual reproduction GO:0019953 546 0.331
negative regulation of biological process GO:0048519 567 0.310
developmental process involved in reproduction GO:0003006 1165 0.307
nucleobase containing compound biosynthetic process GO:0034654 184 0.296
biosynthetic process GO:0009058 323 0.291
meiotic nuclear division GO:0007126 300 0.280
positive regulation of rna metabolic process GO:0051254 103 0.278
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.273
regulation of rna metabolic process GO:0051252 173 0.263
cellular nitrogen compound biosynthetic process GO:0044271 192 0.260
transport GO:0006810 1093 0.258
cell cycle GO:0007049 526 0.256
multicellular organismal aging GO:0010259 812 0.256
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.255
cell projection organization GO:0030030 231 0.252
nucleobase containing compound metabolic process GO:0006139 406 0.239
regulation of organelle organization GO:0033043 164 0.235
gene expression GO:0010467 412 0.233
multi organism reproductive process GO:0044703 867 0.233
regulation of multicellular organismal process GO:0051239 726 0.224
cellular response to chemical stimulus GO:0070887 129 0.224
signal transduction GO:0007165 317 0.223
germ cell development GO:0007281 351 0.221
positive regulation of nucleic acid templated transcription GO:1903508 102 0.221
regulation of growth GO:0040008 409 0.221
positive regulation of metabolic process GO:0009893 187 0.220
regulation of nematode larval development GO:0061062 260 0.219
positive regulation of gene expression GO:0010628 112 0.218
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.214
locomotion GO:0040011 1634 0.214
gamete generation GO:0007276 461 0.208
catabolic process GO:0009056 318 0.208
nucleic acid metabolic process GO:0090304 299 0.207
neurogenesis GO:0022008 236 0.204
positive regulation of macromolecule metabolic process GO:0010604 149 0.203
regulation of transcription dna templated GO:0006355 164 0.203
wnt signaling pathway GO:0016055 27 0.203
positive regulation of rna biosynthetic process GO:1902680 102 0.202
meiotic cell cycle process GO:1903046 170 0.200
rna biosynthetic process GO:0032774 169 0.198
gonad development GO:0008406 840 0.197
cell death GO:0008219 547 0.197
regulation of rna biosynthetic process GO:2001141 165 0.194
cellular biosynthetic process GO:0044249 315 0.189
transcription dna templated GO:0006351 168 0.188
negative regulation of macromolecule metabolic process GO:0010605 229 0.187
negative regulation of biosynthetic process GO:0009890 65 0.186
cellular macromolecule biosynthetic process GO:0034645 247 0.184
organic cyclic compound biosynthetic process GO:1901362 195 0.178
macromolecule catabolic process GO:0009057 202 0.177
post embryonic organ development GO:0048569 336 0.177
regulation of biosynthetic process GO:0009889 189 0.176
regulation of nitrogen compound metabolic process GO:0051171 222 0.176
positive regulation of multicellular organismal process GO:0051240 417 0.173
regulation of biological quality GO:0065008 741 0.172
aging GO:0007568 812 0.171
signaling GO:0023052 401 0.169
multicellular organismal reproductive behavior GO:0033057 384 0.165
regulation of vulval development GO:0040028 248 0.162
cell proliferation GO:0008283 116 0.153
behavior GO:0007610 527 0.152
organic substance biosynthetic process GO:1901576 323 0.151
regulation of primary metabolic process GO:0080090 292 0.150
regulation of macromolecule biosynthetic process GO:0010556 189 0.149
regulation of cellular metabolic process GO:0031323 305 0.148
negative regulation of developmental process GO:0051093 227 0.148
positive regulation of transcription dna templated GO:0045893 102 0.145
neuron projection development GO:0031175 187 0.141
vulval development GO:0040025 333 0.138
positive regulation of cellular metabolic process GO:0031325 178 0.136
macromolecule biosynthetic process GO:0009059 250 0.136
cellular catabolic process GO:0044248 199 0.135
macromolecule localization GO:0033036 771 0.134
regulation of nucleic acid templated transcription GO:1903506 165 0.133
digestive tract morphogenesis GO:0048546 76 0.132
regulation of cellular component organization GO:0051128 248 0.129
single organism transport GO:0044765 447 0.127
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.126
positive regulation of cell communication GO:0010647 69 0.125
negative regulation of cellular biosynthetic process GO:0031327 65 0.125
chromosome organization GO:0051276 104 0.123
tissue development GO:0009888 112 0.123
posttranscriptional regulation of gene expression GO:0010608 166 0.122
axon development GO:0061564 163 0.120
negative regulation of cellular process GO:0048523 239 0.120
multi multicellular organism process GO:0044706 390 0.119
single organism localization GO:1902578 518 0.119
multi organism reproductive behavior GO:0044705 387 0.118
cytoskeleton organization GO:0007010 339 0.118
heterocycle biosynthetic process GO:0018130 187 0.117
organelle organization GO:0006996 783 0.115
positive regulation of growth GO:0045927 369 0.115
regulation of multicellular organismal development GO:2000026 317 0.114
meiotic chromosome segregation GO:0045132 139 0.109
regulation of cell cycle process GO:0010564 145 0.108
multi organism behavior GO:0051705 389 0.108
positive regulation of cellular biosynthetic process GO:0031328 109 0.105
growth GO:0040007 562 0.104
protein catabolic process GO:0030163 162 0.103
multicellular organism growth GO:0035264 385 0.103
programmed cell death GO:0012501 500 0.103
cell fate commitment GO:0045165 139 0.099
nervous system development GO:0007399 253 0.098
cellular response to organic substance GO:0071310 119 0.097
positive regulation of developmental process GO:0051094 408 0.095
positive regulation of multicellular organism growth GO:0040018 352 0.094
organic substance catabolic process GO:1901575 294 0.093
regulation of multicellular organism growth GO:0040014 373 0.093
oogenesis GO:0048477 229 0.090
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.088
negative regulation of rna biosynthetic process GO:1902679 53 0.088
macromolecular complex subunit organization GO:0043933 320 0.088
regulation of cell proliferation GO:0042127 105 0.087
nucleic acid templated transcription GO:0097659 169 0.087
apoptotic process GO:0006915 478 0.087
neuron development GO:0048666 199 0.086
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.084
cell migration GO:0016477 306 0.084
macromolecule modification GO:0043412 218 0.083
regulation of cell cycle GO:0051726 194 0.083
positive regulation of biosynthetic process GO:0009891 109 0.081
negative regulation of vulval development GO:0040027 206 0.080
mitotic nuclear division GO:0007067 89 0.079
gene silencing GO:0016458 143 0.079
embryonic morphogenesis GO:0048598 152 0.079
negative regulation of nematode larval development GO:0061064 208 0.077
chromatin remodeling GO:0006338 2 0.075
cellular protein modification process GO:0006464 207 0.074
negative regulation of multicellular organismal process GO:0051241 236 0.070
maintenance of location GO:0051235 580 0.070
female gamete generation GO:0007292 254 0.070
muscle tissue development GO:0060537 1 0.069
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.069
transcription from rna polymerase ii promoter GO:0006366 149 0.069
mitotic cell cycle process GO:1903047 194 0.067
cell part morphogenesis GO:0032990 152 0.067
localization of cell GO:0051674 313 0.067
anatomical structure formation involved in morphogenesis GO:0048646 250 0.066
negative regulation of cellular metabolic process GO:0031324 95 0.066
negative regulation of post embryonic development GO:0048581 208 0.066
death GO:0016265 547 0.066
negative regulation of metabolic process GO:0009892 240 0.065
regionalization GO:0003002 31 0.065
regulation of signaling GO:0023051 172 0.063
reproductive behavior GO:0019098 387 0.063
developmental growth GO:0048589 412 0.063
cellular component movement GO:0006928 388 0.063
lipid storage GO:0019915 565 0.062
macromolecular complex assembly GO:0065003 193 0.062
response to external stimulus GO:0009605 289 0.062
inductive cell migration GO:0040039 145 0.061
regulation of neuron differentiation GO:0045664 40 0.061
cell morphogenesis GO:0000902 163 0.061
organelle fission GO:0048285 363 0.061
organelle localization GO:0051640 127 0.060
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.060
establishment of localization in cell GO:0051649 318 0.060
regulation of developmental growth GO:0048638 389 0.059
response to chemical GO:0042221 356 0.059
cellular localization GO:0051641 360 0.058
neuron differentiation GO:0030182 217 0.058
aromatic compound biosynthetic process GO:0019438 192 0.057
embryonic pattern specification GO:0009880 21 0.057
regulation of cell division GO:0051302 142 0.057
regulation of gene expression epigenetic GO:0040029 163 0.055
protein complex subunit organization GO:0071822 280 0.055
generation of neurons GO:0048699 235 0.055
single organism catabolic process GO:0044712 129 0.054
organelle assembly GO:0070925 214 0.054
cellular component assembly GO:0022607 293 0.053
cell development GO:0048468 696 0.053
lipid localization GO:0010876 573 0.053
single organism signaling GO:0044700 401 0.052
cellular component biogenesis GO:0044085 297 0.051
proteolysis GO:0006508 61 0.051
regulation of post embryonic development GO:0048580 260 0.050
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.050
muscle structure development GO:0061061 191 0.050
microtubule based process GO:0007017 182 0.050
positive regulation of developmental growth GO:0048639 354 0.049
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.049
tube morphogenesis GO:0035239 79 0.048
cell motility GO:0048870 313 0.048
protein modification process GO:0036211 207 0.047
response to organonitrogen compound GO:0010243 15 0.047
neuron projection guidance GO:0097485 82 0.046
phagocytosis GO:0006909 115 0.044
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.044
spindle localization GO:0051653 51 0.044
cell division GO:0051301 262 0.044
oocyte differentiation GO:0009994 45 0.043
regulation of neurogenesis GO:0050767 40 0.043
negative regulation of transcription dna templated GO:0045892 53 0.043
axis specification GO:0009798 23 0.043
blastoderm segmentation GO:0007350 7 0.042
negative regulation of programmed cell death GO:0043069 19 0.042
response to organic substance GO:0010033 131 0.041
regulation of response to stimulus GO:0048583 243 0.041
oocyte axis specification GO:0007309 2 0.041
axonogenesis GO:0007409 102 0.040
anterior posterior pattern specification GO:0009952 27 0.040
gastrulation GO:0007369 58 0.040
canonical wnt signaling pathway GO:0060070 3 0.039
cell surface receptor signaling pathway GO:0007166 149 0.038
cell projection morphogenesis GO:0048858 148 0.038
establishment of spindle localization GO:0051293 51 0.038
maintenance of protein location in cell GO:0032507 12 0.038
segmentation GO:0035282 7 0.037
proteolysis involved in cellular protein catabolic process GO:0051603 32 0.037
positive regulation of signal transduction GO:0009967 40 0.037
posttranscriptional gene silencing by rna GO:0035194 143 0.037
protein localization GO:0008104 205 0.036
establishment of mitotic spindle localization GO:0040001 41 0.036
intracellular receptor signaling pathway GO:0030522 2 0.036
regulation of nuclear division GO:0051783 115 0.036
oocyte development GO:0048599 44 0.035
digestive system development GO:0055123 122 0.035
regulation of cell death GO:0010941 65 0.035
digestive tract development GO:0048565 122 0.035
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.035
positive regulation of neurogenesis GO:0050769 4 0.035
regulation of cytoskeleton organization GO:0051493 41 0.035
response to wounding GO:0009611 4 0.034
regulation of chromosome organization GO:0033044 20 0.033
organ morphogenesis GO:0009887 67 0.033
protein complex assembly GO:0006461 186 0.032
establishment of spindle orientation GO:0051294 34 0.031
regulation of protein metabolic process GO:0051246 81 0.031
negative regulation of rna metabolic process GO:0051253 53 0.031
phosphate containing compound metabolic process GO:0006796 232 0.031
regulation of cellular component size GO:0032535 40 0.030
small molecule metabolic process GO:0044281 186 0.030
regulation of apoptotic process GO:0042981 36 0.030
skeletal muscle organ development GO:0060538 3 0.029
female meiotic division GO:0007143 17 0.029
establishment of cell polarity GO:0030010 46 0.029
gene silencing by rna GO:0031047 143 0.028
posttranscriptional gene silencing GO:0016441 143 0.028
rna interference GO:0016246 137 0.028
ubiquitin dependent protein catabolic process GO:0006511 32 0.028
regulation of cellular protein metabolic process GO:0032268 75 0.028
regulation of locomotion GO:0040012 161 0.027
cellular macromolecule catabolic process GO:0044265 73 0.027
regulation of cellular catabolic process GO:0031329 51 0.027
modification dependent macromolecule catabolic process GO:0043632 32 0.027
response to abiotic stimulus GO:0009628 152 0.027
male anatomical structure morphogenesis GO:0090598 78 0.027
negative regulation of cell cycle GO:0045786 53 0.027
cell type specific apoptotic process GO:0097285 4 0.026
negative regulation of nucleic acid templated transcription GO:1903507 53 0.026
head development GO:0060322 1 0.025
regulation of epithelial cell proliferation GO:0050678 1 0.025
regulation of meiotic cell cycle GO:0051445 136 0.025
cell cell signaling GO:0007267 118 0.025
muscle cell differentiation GO:0042692 171 0.024
regulation of mitotic cell cycle GO:0007346 76 0.024
chromatin organization GO:0006325 32 0.024
intracellular signal transduction GO:0035556 96 0.024
cellular component morphogenesis GO:0032989 318 0.024
sensory organ morphogenesis GO:0090596 2 0.024
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.024
modification dependent protein catabolic process GO:0019941 32 0.024
establishment of organelle localization GO:0051656 123 0.023
protein complex biogenesis GO:0070271 186 0.023
proteasomal protein catabolic process GO:0010498 20 0.023
chromatin modification GO:0016568 32 0.023
establishment of mitotic spindle orientation GO:0000132 28 0.023
cellular protein catabolic process GO:0044257 37 0.023
nucleoside catabolic process GO:0009164 78 0.022
establishment or maintenance of cell polarity GO:0007163 63 0.022
cell projection assembly GO:0030031 35 0.022
axonal fasciculation GO:0007413 79 0.022
oocyte construction GO:0007308 2 0.022
organonitrogen compound metabolic process GO:1901564 151 0.021
response to other organism GO:0051707 101 0.021
negative regulation of cellular protein metabolic process GO:0032269 27 0.021
neuron recognition GO:0008038 83 0.021
regulation of programmed cell death GO:0043067 50 0.021
mitotic sister chromatid segregation GO:0000070 38 0.020
regulation of cell communication GO:0010646 176 0.020
epithelial cell proliferation GO:0050673 1 0.020
regulation of mitosis GO:0007088 18 0.020
response to oxygen containing compound GO:1901700 44 0.020
taxis GO:0042330 128 0.020
regulation of multi organism process GO:0043900 69 0.020
mitotic sister chromatid separation GO:0051306 13 0.020
regulation of microtubule cytoskeleton organization GO:0070507 21 0.020
positive regulation of intracellular transport GO:0032388 2 0.019
striated muscle cell differentiation GO:0051146 158 0.019
chromatin assembly or disassembly GO:0006333 1 0.019
rna localization GO:0006403 3 0.019
striated muscle cell development GO:0055002 157 0.019
cell morphogenesis involved in differentiation GO:0000904 112 0.019
positive regulation of protein metabolic process GO:0051247 45 0.018
negative regulation of response to stimulus GO:0048585 73 0.018
tube development GO:0035295 126 0.018
regulation of apoptotic signaling pathway GO:2001233 1 0.018
cuticle development GO:0042335 100 0.018
regulation of cell morphogenesis GO:0022604 40 0.018
cellular macromolecular complex assembly GO:0034622 184 0.017
actin filament based process GO:0030029 191 0.017
cell growth GO:0016049 44 0.017
cellular amine metabolic process GO:0044106 15 0.017
response to external biotic stimulus GO:0043207 101 0.017
anterior posterior axis specification GO:0009948 17 0.017
cellular response to abiotic stimulus GO:0071214 4 0.016
muscle cell development GO:0055001 158 0.016
cellular response to stress GO:0033554 162 0.016
neuron projection morphogenesis GO:0048812 114 0.016
mesoderm morphogenesis GO:0048332 24 0.016
cell matrix adhesion GO:0007160 1 0.015
dendrite development GO:0016358 42 0.015
cellular component assembly involved in morphogenesis GO:0010927 183 0.015
apical junction assembly GO:0043297 1 0.015
single organism biosynthetic process GO:0044711 91 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 20 0.015
protein oligomerization GO:0051259 4 0.015
cellular macromolecule localization GO:0070727 75 0.015
g1 s transition of mitotic cell cycle GO:0000082 2 0.015
fertilization GO:0009566 63 0.015
pattern specification process GO:0007389 59 0.014
regulation of cellular component biogenesis GO:0044087 26 0.014
positive regulation of cellular component organization GO:0051130 34 0.014
regulation of cell projection assembly GO:0060491 3 0.014
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.014
dauer larval development GO:0040024 92 0.014
negative regulation of protein metabolic process GO:0051248 27 0.014
response to extracellular stimulus GO:0009991 38 0.014
tissue morphogenesis GO:0048729 65 0.014
collagen and cuticulin based cuticle development GO:0040002 99 0.014
regulation of microtubule based process GO:0032886 21 0.014
cell cycle phase transition GO:0044770 19 0.014
regulation of localization GO:0032879 194 0.014
heterocycle catabolic process GO:0046700 119 0.014
regulation of protein stability GO:0031647 3 0.014
amine metabolic process GO:0009308 15 0.013
regulation of signal transduction GO:0009966 135 0.013
cellular protein localization GO:0034613 75 0.013
single organism cellular localization GO:1902580 72 0.013
carboxylic acid metabolic process GO:0019752 34 0.013
cellular response to oxygen containing compound GO:1901701 21 0.013
negative regulation of cell death GO:0060548 21 0.013
negative regulation of mitotic cell cycle GO:0045930 42 0.013
response to acid chemical GO:0001101 4 0.013
regulation of neuron projection development GO:0010975 31 0.013
negative regulation of neurogenesis GO:0050768 4 0.012
regulation of protein localization GO:0032880 50 0.012
sister chromatid segregation GO:0000819 46 0.012
dna metabolic process GO:0006259 74 0.012
response to temperature stimulus GO:0009266 66 0.012
male sex differentiation GO:0046661 86 0.012
nematode male tail tip morphogenesis GO:0045138 77 0.012
regulation of cellular amine metabolic process GO:0033238 0 0.012
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 2 0.012
positive regulation of neuron differentiation GO:0045666 4 0.012
axon guidance GO:0007411 82 0.012
oxoacid metabolic process GO:0043436 47 0.012
regulation of organ morphogenesis GO:2000027 4 0.012
organophosphate metabolic process GO:0019637 125 0.012
defense response to other organism GO:0098542 100 0.012
modification of morphology or physiology of other organism GO:0035821 2 0.012
organic acid metabolic process GO:0006082 47 0.012
regulation of chromatin modification GO:1903308 2 0.011
molting cycle GO:0042303 281 0.011
protein modification by small protein conjugation or removal GO:0070647 40 0.011
regulation of filopodium assembly GO:0051489 2 0.011
regulation of cellular ketone metabolic process GO:0010565 3 0.011
positive regulation of protein transport GO:0051222 4 0.011
neuromuscular junction development GO:0007528 2 0.011
chromosome separation GO:0051304 19 0.011
response to nutrient levels GO:0031667 35 0.011
regulation of lipid metabolic process GO:0019216 4 0.011
cellular response to extracellular stimulus GO:0031668 16 0.011
regulation of cytoplasmic transport GO:1903649 3 0.011
defense response GO:0006952 296 0.011
protein modification by small protein conjugation GO:0032446 31 0.011
positive regulation of signaling GO:0023056 66 0.011
cellular amino acid metabolic process GO:0006520 15 0.011
immune response GO:0006955 192 0.011
regulation of canonical wnt signaling pathway GO:0060828 1 0.011
regulation of cell motility GO:2000145 57 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
epithelium development GO:0060429 68 0.011
response to biotic stimulus GO:0009607 101 0.011
nucleobase containing compound catabolic process GO:0034655 114 0.010
positive regulation of response to stimulus GO:0048584 55 0.010
negative regulation of cell cycle process GO:0010948 12 0.010
regulation of wnt signaling pathway GO:0030111 9 0.010
actin cytoskeleton organization GO:0030036 184 0.010
negative regulation of wnt signaling pathway GO:0030178 6 0.010
regulation of epithelial cell differentiation GO:0030856 4 0.010
cell substrate adhesion GO:0031589 1 0.010
response to bacterium GO:0009617 86 0.010
chemotaxis GO:0006935 120 0.010
negative regulation of apoptotic process GO:0043066 17 0.010
regulation of cell development GO:0060284 49 0.010
muscle organ development GO:0007517 26 0.010
internal peptidyl lysine acetylation GO:0018393 3 0.010
phosphorus metabolic process GO:0006793 232 0.010

lsy-22 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.049
disease of cellular proliferation DOID:14566 0 0.049
organ system cancer DOID:0050686 0 0.049
gastrointestinal system cancer DOID:3119 0 0.015
disease of anatomical entity DOID:7 0 0.013
nervous system disease DOID:863 0 0.011