Caenorhabditis elegans

114 known processes

let-756 (CELE_C05D11.4)

Protein LET-756

let-756 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism signaling GO:0044700 401 0.578
cellular localization GO:0051641 360 0.520
Human Mouse
establishment of localization GO:0051234 1171 0.477
Human Mouse
signaling GO:0023052 401 0.474
single organism organelle organization GO:1902589 501 0.454
Mouse
positive regulation of locomotion GO:0040017 42 0.435
Human Zebrafish Mouse
reproductive system development GO:0061458 850 0.417
Mouse
nucleobase containing compound metabolic process GO:0006139 406 0.398
Human Mouse
sex differentiation GO:0007548 909 0.383
Mouse
gonad development GO:0008406 840 0.379
Mouse
cytoskeleton organization GO:0007010 339 0.375
Mouse
cell cell signaling GO:0007267 118 0.361
Mouse
genitalia development GO:0048806 741 0.338
Mouse
positive regulation of signaling GO:0023056 66 0.335
Human Zebrafish Mouse Fly
post embryonic development GO:0009791 2152 0.310
pattern specification process GO:0007389 59 0.303
Zebrafish Mouse
reproductive structure development GO:0048608 850 0.303
Mouse
organelle organization GO:0006996 783 0.302
Mouse
phosphorus metabolic process GO:0006793 232 0.302
Human Mouse Fly
mitotic cell cycle process GO:1903047 194 0.297
Mouse
single organism localization GO:1902578 518 0.294
Human Mouse
aging GO:0007568 812 0.283
Rat
cellular component movement GO:0006928 388 0.266
phosphate containing compound metabolic process GO:0006796 232 0.266
Human Mouse Fly
cell fate commitment GO:0045165 139 0.264
Human Zebrafish Mouse
cellular response to chemical stimulus GO:0070887 129 0.255
organ development GO:0048513 1102 0.254
Human Zebrafish Mouse Rat Fly
positive regulation of cellular process GO:0048522 332 0.249
Human Zebrafish Mouse Rat Fly
regulation of locomotion GO:0040012 161 0.236
endocytosis GO:0006897 819 0.233
development of primary sexual characteristics GO:0045137 840 0.229
Mouse
skeletal muscle organ development GO:0060538 3 0.226
positive regulation of epithelial cell proliferation GO:0050679 1 0.221
Human Mouse
hermaphrodite genitalia development GO:0040035 734 0.212
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.209
Human Mouse
single organism transport GO:0044765 447 0.204
Human Mouse
generation of neurons GO:0048699 235 0.203
developmental process involved in reproduction GO:0003006 1165 0.194
Mouse
transport GO:0006810 1093 0.193
Human Mouse
regulation of signaling GO:0023051 172 0.192
Human Zebrafish Mouse Fly
head development GO:0060322 1 0.191
Zebrafish Mouse
positive regulation of cell communication GO:0010647 69 0.188
Human Zebrafish Mouse Fly
neuron differentiation GO:0030182 217 0.187
death GO:0016265 547 0.184
Human Zebrafish Mouse
embryo development ending in birth or egg hatching GO:0009792 2992 0.183
Mouse Rat
regulation of gene expression GO:0010468 366 0.181
Human Mouse
positive regulation of metabolic process GO:0009893 187 0.180
Human Mouse Fly
organelle localization GO:0051640 127 0.177
Mouse
positive regulation of response to stimulus GO:0048584 55 0.176
Human Zebrafish Mouse Fly
establishment of localization in cell GO:0051649 318 0.174
Human Mouse
female gamete generation GO:0007292 254 0.172
response to chemical GO:0042221 356 0.172
behavior GO:0007610 527 0.170
multicellular organismal reproductive behavior GO:0033057 384 0.170
protein phosphorylation GO:0006468 85 0.167
Mouse Fly
embryo development GO:0009790 3052 0.167
Zebrafish Mouse Rat
positive regulation of nematode larval development GO:0061063 54 0.162
apoptotic process GO:0006915 478 0.162
Zebrafish Mouse
neuron projection morphogenesis GO:0048812 114 0.160
heterocycle biosynthetic process GO:0018130 187 0.158
Human Mouse
regulation of cellular metabolic process GO:0031323 305 0.158
Human Mouse Fly
single organism cellular localization GO:1902580 72 0.157
Mouse
muscle tissue development GO:0060537 1 0.155
Human Mouse Rat
regionalization GO:0003002 31 0.154
Zebrafish Mouse
synaptic transmission GO:0007268 106 0.153
Mouse
protein complex subunit organization GO:0071822 280 0.152
Mouse
taxis GO:0042330 128 0.149
aromatic compound biosynthetic process GO:0019438 192 0.146
Human Mouse
cell cycle GO:0007049 526 0.146
Mouse
germ cell development GO:0007281 351 0.145
cellular protein modification process GO:0006464 207 0.143
Mouse Fly
cell development GO:0048468 696 0.143
cell death GO:0008219 547 0.143
Human Zebrafish Mouse
single organism reproductive process GO:0044702 1196 0.142
Mouse
positive regulation of vulval development GO:0040026 52 0.142
positive regulation of developmental process GO:0051094 408 0.141
Human Zebrafish Mouse Rat
single organism behavior GO:0044708 83 0.141
Mouse
regulation of developmental process GO:0050793 684 0.141
regulation of transcription dna templated GO:0006355 164 0.140
Human Mouse
protein modification process GO:0036211 207 0.139
Mouse Fly
negative regulation of metabolic process GO:0009892 240 0.138
Mouse
positive regulation of phosphorus metabolic process GO:0010562 56 0.135
Human Mouse Fly
gene expression GO:0010467 412 0.133
Human Mouse
regulation of cell communication GO:0010646 176 0.133
Human Zebrafish Mouse Fly
regulation of biological quality GO:0065008 741 0.132
small molecule metabolic process GO:0044281 186 0.131
Human
spindle organization GO:0007051 92 0.131
regulation of molecular function GO:0065009 89 0.130
Human Mouse Fly
multicellular organism reproduction GO:0032504 819 0.128
negative regulation of cellular process GO:0048523 239 0.128
muscle structure development GO:0061061 191 0.126
Human Mouse Rat
cell surface receptor signaling pathway GO:0007166 149 0.124
cellular protein metabolic process GO:0044267 279 0.124
Mouse Fly
cellular catabolic process GO:0044248 199 0.124
cellular component biogenesis GO:0044085 297 0.121
Mouse Fly
response to wounding GO:0009611 4 0.121
Human Zebrafish Mouse Rat
transcription dna templated GO:0006351 168 0.121
Human Mouse
locomotion GO:0040011 1634 0.121
axon guidance GO:0007411 82 0.121
negative regulation of biological process GO:0048519 567 0.120
rna biosynthetic process GO:0032774 169 0.119
Human Mouse
positive regulation of signal transduction GO:0009967 40 0.117
Human Zebrafish Mouse Fly
multi organism reproductive behavior GO:0044705 387 0.115
rho protein signal transduction GO:0007266 2 0.115
signal transduction GO:0007165 317 0.114
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.114
Human Mouse
vesicle mediated transport GO:0016192 852 0.113
macromolecular complex subunit organization GO:0043933 320 0.112
Mouse
regulation of rna biosynthetic process GO:2001141 165 0.112
Human Mouse
cellular nitrogen compound biosynthetic process GO:0044271 192 0.111
Human Mouse
cell migration GO:0016477 306 0.111
Human Zebrafish Mouse Fly
regulation of phosphorus metabolic process GO:0051174 81 0.108
Human Mouse Fly
macromolecule modification GO:0043412 218 0.107
Mouse Fly
reproductive behavior GO:0019098 387 0.107
biosynthetic process GO:0009058 323 0.107
Human Mouse
regulation of cell fate commitment GO:0010453 22 0.106
Human
multicellular organismal reproductive process GO:0048609 815 0.106
regulation of multicellular organismal process GO:0051239 726 0.105
positive regulation of rna metabolic process GO:0051254 103 0.102
Human Mouse
negative regulation of programmed cell death GO:0043069 19 0.102
Zebrafish Mouse
catabolic process GO:0009056 318 0.102
Human
response to organic substance GO:0010033 131 0.101
regulation of cell motility GO:2000145 57 0.100
Human Zebrafish Mouse Fly
carbohydrate derivative metabolic process GO:1901135 141 0.098
Human
macromolecule biosynthetic process GO:0009059 250 0.098
Human Mouse
nervous system development GO:0007399 253 0.098
epithelial tube morphogenesis GO:0060562 1 0.097
Human Mouse
regulation of growth GO:0040008 409 0.097
cell motility GO:0048870 313 0.097
Human Zebrafish Mouse Fly
nucleic acid templated transcription GO:0097659 169 0.096
Human Mouse
nucleobase containing compound biosynthetic process GO:0034654 184 0.096
Human Mouse
growth GO:0040007 562 0.095
axonogenesis GO:0007409 102 0.095
organic substance catabolic process GO:1901575 294 0.094
Human
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.094
cellular response to endogenous stimulus GO:0071495 32 0.093
regulation of response to stimulus GO:0048583 243 0.093
chemotaxis GO:0006935 120 0.091
sexual reproduction GO:0019953 546 0.091
ribonucleoside catabolic process GO:0042454 77 0.091
positive regulation of multicellular organismal process GO:0051240 417 0.091
Human Zebrafish Mouse Rat
neuron projection guidance GO:0097485 82 0.090
secretion GO:0046903 147 0.089
multicellular organismal aging GO:0010259 812 0.088
localization of cell GO:0051674 313 0.087
Human Zebrafish Mouse Fly
cell cycle process GO:0022402 482 0.087
Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.086
Human Mouse
muscle cell differentiation GO:0042692 171 0.086
Mouse
receptor mediated endocytosis GO:0006898 715 0.084
oocyte axis specification GO:0007309 2 0.084
macromolecule catabolic process GO:0009057 202 0.083
Human
regulation of cell differentiation GO:0045595 81 0.083
transmembrane transport GO:0055085 110 0.082
Mouse
actin cytoskeleton organization GO:0030036 184 0.081
regulation of metabolic process GO:0019222 478 0.081
Human Mouse Fly
regulation of primary metabolic process GO:0080090 292 0.081
Human Mouse Fly
macromolecule localization GO:0033036 771 0.079
Mouse
dna metabolic process GO:0006259 74 0.079
cell proliferation GO:0008283 116 0.077
Human Zebrafish Mouse Rat
organic cyclic compound biosynthetic process GO:1901362 195 0.077
Human Mouse
microtubule based process GO:0007017 182 0.076
Mouse
protein metabolic process GO:0019538 422 0.076
Mouse Fly
regulation of nucleic acid templated transcription GO:1903506 165 0.076
Human Mouse
chromosome segregation GO:0007059 180 0.076
muscle organ development GO:0007517 26 0.076
Human Mouse Rat
oogenesis GO:0048477 229 0.075
neurogenesis GO:0022008 236 0.075
establishment of mitotic spindle localization GO:0040001 41 0.075
Mouse
determination of adult lifespan GO:0008340 812 0.075
gamete generation GO:0007276 461 0.075
mitotic nuclear division GO:0007067 89 0.075
secretion by cell GO:0032940 138 0.074
actin filament based process GO:0030029 191 0.074
regulation of nematode larval development GO:0061062 260 0.073
positive regulation of phosphate metabolic process GO:0045937 56 0.073
Human Mouse Fly
sensory organ morphogenesis GO:0090596 2 0.073
Zebrafish Mouse
positive regulation of post embryonic development GO:0048582 54 0.073
negative regulation of macromolecule metabolic process GO:0010605 229 0.072
Mouse
organelle fission GO:0048285 363 0.072
purine nucleotide metabolic process GO:0006163 95 0.072
regulation of neuron differentiation GO:0045664 40 0.072
response to external stimulus GO:0009605 289 0.072
multi organism behavior GO:0051705 389 0.071
positive regulation of catabolic process GO:0009896 38 0.071
cellular component morphogenesis GO:0032989 318 0.071
oocyte construction GO:0007308 2 0.070
positive regulation of developmental growth GO:0048639 354 0.070
Human Mouse Rat
meiotic nuclear division GO:0007126 300 0.070
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.069
Human Mouse
organophosphate metabolic process GO:0019637 125 0.069
Human
regulation of cellular component organization GO:0051128 248 0.068
organic substance biosynthetic process GO:1901576 323 0.067
Human Mouse
positive regulation of molecular function GO:0044093 61 0.066
Human Mouse Fly
embryonic morphogenesis GO:0048598 152 0.066
Zebrafish Mouse
regulation of multicellular organism growth GO:0040014 373 0.066
maintenance of location GO:0051235 580 0.066
Human
epithelial cell proliferation GO:0050673 1 0.065
Human Mouse
oocyte differentiation GO:0009994 45 0.065
regulation of cellular biosynthetic process GO:0031326 189 0.065
Human Mouse
cellular component assembly GO:0022607 293 0.064
Mouse Fly
regulation of apoptotic process GO:0042981 36 0.064
Zebrafish Mouse
regulation of cell death GO:0010941 65 0.064
Human Zebrafish Mouse
regulation of localization GO:0032879 194 0.064
cell morphogenesis GO:0000902 163 0.064
regulation of wnt signaling pathway GO:0030111 9 0.064
Zebrafish Mouse
response to biotic stimulus GO:0009607 101 0.063
developmental growth GO:0048589 412 0.063
regulation of signal transduction GO:0009966 135 0.063
Human Zebrafish Mouse Fly
response to fibroblast growth factor GO:0071774 5 0.062
programmed cell death GO:0012501 500 0.062
Zebrafish Mouse
axis specification GO:0009798 23 0.062
Mouse
neuron projection development GO:0031175 187 0.062
positive regulation of biosynthetic process GO:0009891 109 0.062
Human Mouse
positive regulation of cellular biosynthetic process GO:0031328 109 0.062
Human Mouse
regulation of developmental growth GO:0048638 389 0.061
cellular response to organic substance GO:0071310 119 0.061
multi organism reproductive process GO:0044703 867 0.060
regulation of epithelial cell proliferation GO:0050678 1 0.060
Human Mouse
regulation of intracellular signal transduction GO:1902531 77 0.060
Human Mouse Fly
lipid localization GO:0010876 573 0.059
mating behavior GO:0007617 32 0.059
digestive tract development GO:0048565 122 0.059
Mouse
regulation of vulval development GO:0040028 248 0.059
cellular response to growth factor stimulus GO:0071363 18 0.058
small gtpase mediated signal transduction GO:0007264 32 0.058
oviposition GO:0018991 364 0.058
phosphorylation GO:0016310 116 0.057
Human Mouse Fly
carbohydrate derivative catabolic process GO:1901136 82 0.057
Human
regulation of macromolecule biosynthetic process GO:0010556 189 0.057
Human Mouse
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.057
single organism catabolic process GO:0044712 129 0.057
Human
positive regulation of neuron differentiation GO:0045666 4 0.057
Zebrafish
ion transport GO:0006811 113 0.056
Human Mouse
regulation of multicellular organismal development GO:2000026 317 0.056
regulation of nitrogen compound metabolic process GO:0051171 222 0.056
Human Mouse
striated muscle cell differentiation GO:0051146 158 0.056
protein catabolic process GO:0030163 162 0.056
purine nucleoside catabolic process GO:0006152 75 0.056
positive regulation of catalytic activity GO:0043085 59 0.055
Human Mouse Fly
cellular biosynthetic process GO:0044249 315 0.055
Human Mouse
neuron development GO:0048666 199 0.055
regeneration GO:0031099 4 0.054
Zebrafish
nucleoside phosphate metabolic process GO:0006753 108 0.053
response to abiotic stimulus GO:0009628 152 0.053
Human
lipid storage GO:0019915 565 0.053
regulation of cellular protein metabolic process GO:0032268 75 0.053
Mouse Fly
establishment of spindle localization GO:0051293 51 0.053
Mouse
cell type specific apoptotic process GO:0097285 4 0.053
cellular nitrogen compound catabolic process GO:0044270 119 0.052
rna metabolic process GO:0016070 228 0.052
Human Mouse
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.052
Mouse
cell morphogenesis involved in differentiation GO:0000904 112 0.052
purine nucleotide catabolic process GO:0006195 75 0.052
spindle localization GO:0051653 51 0.051
Mouse
regulation of cell migration GO:0030334 55 0.051
Human Zebrafish Mouse Fly
cell growth GO:0016049 44 0.051
embryonic body morphogenesis GO:0010172 49 0.051
regulation of biosynthetic process GO:0009889 189 0.051
Human Mouse
regulation of catabolic process GO:0009894 57 0.051
cell division GO:0051301 262 0.051
Human Mouse
regulation of rna metabolic process GO:0051252 173 0.051
Human Mouse
positive regulation of intracellular signal transduction GO:1902533 24 0.051
Human Mouse Fly
positive regulation of neurogenesis GO:0050769 4 0.051
Zebrafish
multicellular organism growth GO:0035264 385 0.051
glycosyl compound metabolic process GO:1901657 100 0.051
rrna metabolic process GO:0016072 3 0.050
organonitrogen compound metabolic process GO:1901564 151 0.050
Human
intracellular signal transduction GO:0035556 96 0.050
Human Mouse Fly
oocyte development GO:0048599 44 0.049
regulation of synaptic transmission GO:0050804 34 0.049
nucleic acid metabolic process GO:0090304 299 0.049
Human Mouse
protein complex assembly GO:0006461 186 0.049
Mouse
dauer larval development GO:0040024 92 0.049
positive regulation of cell migration GO:0030335 3 0.049
Human Zebrafish Mouse
memory GO:0007613 3 0.049
Mouse
negative regulation of gene expression GO:0010629 217 0.048
Mouse
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.048
regulation of extent of cell growth GO:0061387 20 0.048
ribonucleoside triphosphate metabolic process GO:0009199 87 0.048
mapk cascade GO:0000165 31 0.047
Human Mouse Fly
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.047
ribonucleotide catabolic process GO:0009261 75 0.047
nucleotide metabolic process GO:0009117 108 0.047
regulation of catalytic activity GO:0050790 78 0.046
Human Mouse Fly
vulval development GO:0040025 333 0.046
neuron projection extension GO:1990138 37 0.046
ras protein signal transduction GO:0007265 31 0.046
regulation of cell cycle GO:0051726 194 0.046
Mouse
posttranscriptional regulation of gene expression GO:0010608 166 0.045
macromolecular complex assembly GO:0065003 193 0.045
Mouse
response to osmotic stress GO:0006970 29 0.045
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.045
protein complex biogenesis GO:0070271 186 0.045
Mouse
regulation of cell proliferation GO:0042127 105 0.044
Human Mouse Rat
ribose phosphate metabolic process GO:0019693 99 0.044
nucleoside triphosphate catabolic process GO:0009143 72 0.044
positive regulation of nucleic acid templated transcription GO:1903508 102 0.044
Human Mouse
g protein coupled receptor signaling pathway GO:0007186 46 0.043
positive regulation of multicellular organism growth GO:0040018 352 0.043
cellular macromolecular complex assembly GO:0034622 184 0.043
Mouse
establishment or maintenance of cell polarity GO:0007163 63 0.043
Mouse
positive regulation of stem cell differentiation GO:2000738 1 0.043
aromatic compound catabolic process GO:0019439 116 0.043
response to growth factor GO:0070848 18 0.042
regulation of macromolecule metabolic process GO:0060255 421 0.042
Human Mouse Fly
cellular response to stress GO:0033554 162 0.042
Human
protein localization GO:0008104 205 0.042
Mouse
regulation of nucleocytoplasmic transport GO:0046822 3 0.042
positive regulation of macromolecule metabolic process GO:0010604 149 0.042
Human Mouse Fly
regulation of gene expression epigenetic GO:0040029 163 0.042
striated muscle cell development GO:0055002 157 0.041
purine ribonucleotide metabolic process GO:0009150 95 0.041
enzyme linked receptor protein signaling pathway GO:0007167 50 0.041
anatomical structure formation involved in morphogenesis GO:0048646 250 0.041
Human Zebrafish Mouse Rat Fly
regulation of mitotic cell cycle GO:0007346 76 0.040
Mouse
cell projection morphogenesis GO:0048858 148 0.040
regulation of anatomical structure morphogenesis GO:0022603 51 0.040
establishment of organelle localization GO:0051656 123 0.040
Mouse
inductive cell migration GO:0040039 145 0.040
regulation of cytoplasmic transport GO:1903649 3 0.040
positive regulation of mapk cascade GO:0043410 14 0.039
Human Mouse Fly
nucleoside metabolic process GO:0009116 99 0.039
regulation of neurogenesis GO:0050767 40 0.039
body morphogenesis GO:0010171 620 0.039
organic cyclic compound catabolic process GO:1901361 119 0.039
regulation of cell fate specification GO:0042659 22 0.039
Human
cellular response to abiotic stimulus GO:0071214 4 0.039
peptidyl tyrosine phosphorylation GO:0018108 2 0.039
regulation of apoptotic signaling pathway GO:2001233 1 0.039
Mouse
regulation of phosphate metabolic process GO:0019220 81 0.038
Human Mouse Fly
ribonucleoside metabolic process GO:0009119 98 0.038
negative regulation of apoptotic process GO:0043066 17 0.038
Zebrafish Mouse
purine ribonucleoside catabolic process GO:0046130 75 0.037
purine nucleoside triphosphate catabolic process GO:0009146 72 0.037
regulation of cell cycle process GO:0010564 145 0.037
metal ion transport GO:0030001 49 0.037
Human Mouse
organic substance transport GO:0071702 113 0.037
Mouse
phagocytosis GO:0006909 115 0.037
negative regulation of response to stimulus GO:0048585 73 0.037
Human Mouse
molting cycle GO:0042303 281 0.037
Mouse
positive regulation of gene expression GO:0010628 112 0.036
Human Mouse
meiotic cell cycle GO:0051321 335 0.036
single organism intracellular transport GO:1902582 70 0.036
Human Mouse
multi multicellular organism process GO:0044706 390 0.036
negative regulation of signal transduction GO:0009968 60 0.036
Mouse
regulation of cell projection organization GO:0031344 38 0.036
cellular protein complex assembly GO:0043623 178 0.035
Mouse
cell part morphogenesis GO:0032990 152 0.035
muscle cell development GO:0055001 158 0.035
negative regulation of post embryonic development GO:0048581 208 0.035
modification dependent macromolecule catabolic process GO:0043632 32 0.035
nucleobase containing compound catabolic process GO:0034655 114 0.035
ion transmembrane transport GO:0034220 91 0.035
Mouse
cellular macromolecule biosynthetic process GO:0034645 247 0.035
Human Mouse
digestive system development GO:0055123 122 0.035
Mouse
guanosine containing compound catabolic process GO:1901069 48 0.035
regulation of small gtpase mediated signal transduction GO:0051056 41 0.035
cell maturation GO:0048469 26 0.034
purine ribonucleotide catabolic process GO:0009154 75 0.034
regulation of organ morphogenesis GO:2000027 4 0.034
Mouse
glycosyl compound catabolic process GO:1901658 79 0.034
heterocycle catabolic process GO:0046700 119 0.034
negative regulation of cell communication GO:0010648 61 0.034
Mouse
positive regulation of rna biosynthetic process GO:1902680 102 0.034
Human Mouse
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.034
regulation of cell division GO:0051302 142 0.034
Human
developmental induction GO:0031128 1 0.034
Mouse
regulation of mesoderm development GO:2000380 2 0.034
wnt signaling pathway GO:0016055 27 0.034
Zebrafish Mouse
positive regulation of cell projection organization GO:0031346 4 0.034
phagocytosis engulfment GO:0006911 98 0.033
positive regulation of growth GO:0045927 369 0.033
Human Mouse Rat
cellular protein localization GO:0034613 75 0.033
Mouse
mitotic sister chromatid segregation GO:0000070 38 0.033
regulation of purine nucleotide catabolic process GO:0033121 35 0.033
cellular macromolecule localization GO:0070727 75 0.032
Mouse
nucleotide catabolic process GO:0009166 77 0.032
system process GO:0003008 136 0.032
Mouse
posttranscriptional gene silencing GO:0016441 143 0.031
regulation of protein kinase activity GO:0045859 28 0.031
Mouse Fly
canonical wnt signaling pathway GO:0060070 3 0.031
Mouse
rna localization GO:0006403 3 0.031
oxoacid metabolic process GO:0043436 47 0.031
single organism biosynthetic process GO:0044711 91 0.031
Human
gene silencing by rna GO:0031047 143 0.031
axon development GO:0061564 163 0.031
response to external biotic stimulus GO:0043207 101 0.031
proteolysis GO:0006508 61 0.030
nucleobase containing small molecule metabolic process GO:0055086 115 0.030
response to other organism GO:0051707 101 0.030
regulation of post embryonic development GO:0048580 260 0.030
organophosphate catabolic process GO:0046434 81 0.030
purine containing compound catabolic process GO:0072523 75 0.030
positive regulation of transport GO:0051050 32 0.030
Mouse
neuron recognition GO:0008038 83 0.030
nucleoside catabolic process GO:0009164 78 0.030
regulation of kinase activity GO:0043549 29 0.030
Human Mouse Fly
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.030
Human Mouse
ribonucleoside triphosphate catabolic process GO:0009203 72 0.030
negative regulation of cellular metabolic process GO:0031324 95 0.029
Mouse
detection of external stimulus GO:0009581 4 0.029
rna interference GO:0016246 137 0.029
purine nucleoside metabolic process GO:0042278 92 0.029
response to endogenous stimulus GO:0009719 33 0.029
defense response to other organism GO:0098542 100 0.029
carboxylic acid metabolic process GO:0019752 34 0.029
organelle assembly GO:0070925 214 0.029
myofibril assembly GO:0030239 154 0.029
purine ribonucleoside metabolic process GO:0046128 92 0.029
membrane organization GO:0061024 135 0.028
Mouse
purine containing compound metabolic process GO:0072521 95 0.028
tube development GO:0035295 126 0.028
Human Mouse
positive regulation of cellular metabolic process GO:0031325 178 0.028
Human Mouse Fly
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.028
Human Mouse
positive regulation of small gtpase mediated signal transduction GO:0051057 7 0.028
regulation of cellular component size GO:0032535 40 0.028
digestive tract morphogenesis GO:0048546 76 0.028
Mouse
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.028
Mouse
organ morphogenesis GO:0009887 67 0.028
Human Zebrafish Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 29 0.028
regulation of transport GO:0051049 91 0.028
Mouse
cellular component assembly involved in morphogenesis GO:0010927 183 0.028
Fly
meiotic chromosome segregation GO:0045132 139 0.027
mating GO:0007618 34 0.027
muscle contraction GO:0006936 43 0.027
cell projection organization GO:0030030 231 0.027
tube morphogenesis GO:0035239 79 0.027
Human Mouse
glycoprotein metabolic process GO:0009100 29 0.027
posttranscriptional gene silencing by rna GO:0035194 143 0.027
striated muscle myosin thick filament assembly GO:0071688 138 0.026
ribosome biogenesis GO:0042254 4 0.026
mitotic spindle organization GO:0007052 81 0.026
establishment of mitotic spindle orientation GO:0000132 28 0.026
Mouse
engulfment of apoptotic cell GO:0043652 94 0.026
regulation of nucleoside metabolic process GO:0009118 37 0.026
regulation of development heterochronic GO:0040034 18 0.026
Mouse
post embryonic organ development GO:0048569 336 0.026
regulation of axon extension GO:0030516 20 0.025
purine nucleoside triphosphate metabolic process GO:0009144 87 0.025
positive regulation of intracellular transport GO:0032388 2 0.025
regulation of cellular amine metabolic process GO:0033238 0 0.025
membrane invagination GO:0010324 98 0.025
signal transduction by phosphorylation GO:0023014 31 0.025
Human Mouse Fly
regulation of gastrulation GO:0010470 4 0.025
gene silencing GO:0016458 143 0.025
specification of axis polarity GO:0065001 13 0.025
cellular amine metabolic process GO:0044106 15 0.025
cell substrate adhesion GO:0031589 1 0.025
golgi vesicle transport GO:0048193 3 0.024
negative regulation of signaling GO:0023057 61 0.024
Mouse
regulation of gtp catabolic process GO:0033124 32 0.024
embryonic pattern specification GO:0009880 21 0.024
Zebrafish Mouse
negative regulation of neurogenesis GO:0050768 4 0.024
Mouse
negative regulation of vulval development GO:0040027 206 0.024
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.023
muscle organ morphogenesis GO:0048644 4 0.023
organonitrogen compound catabolic process GO:1901565 90 0.023
Human
organic acid metabolic process GO:0006082 47 0.023
cell fate commitment involved in formation of primary germ layer GO:0060795 33 0.023
regulation of cellular ketone metabolic process GO:0010565 3 0.023
apoptotic cell clearance GO:0043277 111 0.023
nucleoside phosphate catabolic process GO:1901292 77 0.022
regulation of reproductive process GO:2000241 66 0.022
regulation of cellular component movement GO:0051270 62 0.022
actomyosin structure organization GO:0031032 154 0.022
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.022
Mouse
regulation of cell morphogenesis GO:0022604 40 0.022
transcription from rna polymerase ii promoter GO:0006366 149 0.022
Human Mouse
regulation of ras protein signal transduction GO:0046578 41 0.021
amine metabolic process GO:0009308 15 0.021
pronuclear migration GO:0035046 51 0.021
regulation of protein import into nucleus GO:0042306 3 0.021
regulation of hydrolase activity GO:0051336 45 0.021
Human
regulation of neuron projection development GO:0010975 31 0.021
regulation of protein metabolic process GO:0051246 81 0.021
Mouse Fly
regulation of cellular catabolic process GO:0031329 51 0.021
intracellular transport GO:0046907 77 0.021
Human Mouse
regulation of bmp signaling pathway GO:0030510 3 0.021
positive regulation of hydrolase activity GO:0051345 38 0.020
Human
rrna processing GO:0006364 3 0.020
positive regulation of ras protein signal transduction GO:0046579 7 0.020
er nucleus signaling pathway GO:0006984 66 0.020
muscle system process GO:0003012 43 0.020
positive regulation of nucleotide catabolic process GO:0030813 28 0.020
response to topologically incorrect protein GO:0035966 82 0.020
negative regulation of nematode larval development GO:0061064 208 0.020
establishment of cell polarity GO:0030010 46 0.020
Mouse
negative regulation of cell cycle GO:0045786 53 0.020
positive regulation of transcription dna templated GO:0045893 102 0.020
Human Mouse
guanosine containing compound metabolic process GO:1901068 49 0.020
gtp catabolic process GO:0006184 46 0.020
hormone transport GO:0009914 2 0.020
regulation of muscle contraction GO:0006937 20 0.019

let-756 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.039
disease of cellular proliferation DOID:14566 0 0.038
cancer DOID:162 0 0.031
cardiovascular system disease DOID:1287 0 0.030
musculoskeletal system disease DOID:17 0 0.028
organ system cancer DOID:0050686 0 0.027