Caenorhabditis elegans

0 known processes

lec-2 (CELE_F52H3.7)

Protein LEC-2

lec-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2152 0.444
embryo development ending in birth or egg hatching GO:0009792 2992 0.367
Worm
embryo development GO:0009790 3052 0.316
Worm
single organism reproductive process GO:0044702 1196 0.226
establishment of localization GO:0051234 1171 0.221
transport GO:0006810 1093 0.207
locomotion GO:0040011 1634 0.190
organic cyclic compound biosynthetic process GO:1901362 195 0.190
cell development GO:0048468 696 0.188
endocytosis GO:0006897 819 0.172
regulation of developmental process GO:0050793 684 0.163
muscle tissue development GO:0060537 1 0.154
oviposition GO:0018991 364 0.149
single organism transport GO:0044765 447 0.143
gene expression GO:0010467 412 0.143
reproductive system development GO:0061458 850 0.139
nucleobase containing compound biosynthetic process GO:0034654 184 0.136
single organism localization GO:1902578 518 0.129
sex differentiation GO:0007548 909 0.126
nucleobase containing compound metabolic process GO:0006139 406 0.125
muscle organ morphogenesis GO:0048644 4 0.125
gonad development GO:0008406 840 0.121
muscle structure development GO:0061061 191 0.119
vesicle mediated transport GO:0016192 852 0.114
regulation of multicellular organismal process GO:0051239 726 0.114
multicellular organismal aging GO:0010259 812 0.111
reproductive structure development GO:0048608 850 0.110
multicellular organism reproduction GO:0032504 819 0.107
positive regulation of rna metabolic process GO:0051254 103 0.104
transcription from rna polymerase ii promoter GO:0006366 149 0.103
body morphogenesis GO:0010171 620 0.099
phosphate containing compound metabolic process GO:0006796 232 0.099
positive regulation of multicellular organism growth GO:0040018 352 0.098
aromatic compound biosynthetic process GO:0019438 192 0.096
growth GO:0040007 562 0.094
protein metabolic process GO:0019538 422 0.093
heterocycle biosynthetic process GO:0018130 187 0.092
death GO:0016265 547 0.092
system process GO:0003008 136 0.092
multicellular organismal reproductive process GO:0048609 815 0.091
response to abiotic stimulus GO:0009628 152 0.091
multicellular organismal reproductive behavior GO:0033057 384 0.090
aging GO:0007568 812 0.090
regulation of biological quality GO:0065008 741 0.089
determination of adult lifespan GO:0008340 812 0.086
multi organism reproductive process GO:0044703 867 0.082
organ development GO:0048513 1102 0.082
cell migration GO:0016477 306 0.081
organelle organization GO:0006996 783 0.079
biosynthetic process GO:0009058 323 0.077
positive regulation of growth GO:0045927 369 0.075
cellular component movement GO:0006928 388 0.075
cellular biosynthetic process GO:0044249 315 0.074
cellular response to organic substance GO:0071310 119 0.073
Worm
cell cycle process GO:0022402 482 0.072
regulation of rna biosynthetic process GO:2001141 165 0.072
macromolecule localization GO:0033036 771 0.072
developmental process involved in reproduction GO:0003006 1165 0.071
behavior GO:0007610 527 0.070
positive regulation of developmental growth GO:0048639 354 0.069
lipid localization GO:0010876 573 0.068
maintenance of location GO:0051235 580 0.068
nucleic acid templated transcription GO:0097659 169 0.067
organic substance catabolic process GO:1901575 294 0.067
regulation of locomotion GO:0040012 161 0.066
regulation of nucleic acid templated transcription GO:1903506 165 0.065
muscle organ development GO:0007517 26 0.065
multicellular organism growth GO:0035264 385 0.065
development of primary sexual characteristics GO:0045137 840 0.064
negative regulation of cellular process GO:0048523 239 0.062
sexual reproduction GO:0019953 546 0.062
positive regulation of developmental process GO:0051094 408 0.061
anatomical structure formation involved in morphogenesis GO:0048646 250 0.061
phosphorus metabolic process GO:0006793 232 0.059
regulation of developmental growth GO:0048638 389 0.058
muscle system process GO:0003012 43 0.058
rna biosynthetic process GO:0032774 169 0.057
regulation of cell migration GO:0030334 55 0.057
cytoskeleton organization GO:0007010 339 0.057
regulation of multicellular organism growth GO:0040014 373 0.057
apoptotic process GO:0006915 478 0.056
transcription dna templated GO:0006351 168 0.056
lipid storage GO:0019915 565 0.056
regulation of growth GO:0040008 409 0.054
cell death GO:0008219 547 0.054
rna metabolic process GO:0016070 228 0.054
signaling GO:0023052 401 0.053
Worm
developmental growth GO:0048589 412 0.053
response to chemical GO:0042221 356 0.053
Worm
multi organism reproductive behavior GO:0044705 387 0.053
molting cycle GO:0042303 281 0.052
negative regulation of biological process GO:0048519 567 0.051
reproductive behavior GO:0019098 387 0.051
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.051
regulation of rna metabolic process GO:0051252 173 0.050
localization of cell GO:0051674 313 0.050
cellular nitrogen compound biosynthetic process GO:0044271 192 0.050
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.050
muscle cell differentiation GO:0042692 171 0.050
cellular response to chemical stimulus GO:0070887 129 0.049
Worm
regulation of signaling GO:0023051 172 0.049
skeletal muscle organ development GO:0060538 3 0.048
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.048
catabolic process GO:0009056 318 0.048
organelle fission GO:0048285 363 0.048
regulation of primary metabolic process GO:0080090 292 0.047
nucleic acid metabolic process GO:0090304 299 0.045
programmed cell death GO:0012501 500 0.045
positive regulation of multicellular organismal process GO:0051240 417 0.044
multi multicellular organism process GO:0044706 390 0.044
positive regulation of cellular process GO:0048522 332 0.044
regulation of macromolecule metabolic process GO:0060255 421 0.042
cell surface receptor signaling pathway GO:0007166 149 0.042
protein complex subunit organization GO:0071822 280 0.041
regulation of cellular biosynthetic process GO:0031326 189 0.041
negative regulation of gene expression GO:0010629 217 0.041
striated muscle cell differentiation GO:0051146 158 0.040
regulation of transcription dna templated GO:0006355 164 0.040
regulation of gene expression GO:0010468 366 0.040
single organism signaling GO:0044700 401 0.039
Worm
macromolecule biosynthetic process GO:0009059 250 0.039
single organism organelle organization GO:1902589 501 0.038
muscle cell development GO:0055001 158 0.038
cellular component assembly involved in morphogenesis GO:0010927 183 0.037
actin filament based process GO:0030029 191 0.037
multi organism behavior GO:0051705 389 0.037
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.037
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.037
cell cycle GO:0007049 526 0.037
cellular component biogenesis GO:0044085 297 0.036
cell division GO:0051301 262 0.036
organ morphogenesis GO:0009887 67 0.036
striated muscle cell development GO:0055002 157 0.036
meiotic cell cycle GO:0051321 335 0.035
regulation of epithelial cell proliferation GO:0050678 1 0.035
organonitrogen compound metabolic process GO:1901564 151 0.034
regulation of cellular component organization GO:0051128 248 0.034
signal transduction GO:0007165 317 0.034
Worm
regulation of multicellular organismal development GO:2000026 317 0.033
cell motility GO:0048870 313 0.033
establishment of localization in cell GO:0051649 318 0.032
response to organic substance GO:0010033 131 0.032
Worm
genitalia development GO:0048806 741 0.032
heterocycle catabolic process GO:0046700 119 0.032
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.032
nervous system development GO:0007399 253 0.031
phagocytosis GO:0006909 115 0.031
cellular component assembly GO:0022607 293 0.031
organelle assembly GO:0070925 214 0.031
neuron development GO:0048666 199 0.031
macromolecule catabolic process GO:0009057 202 0.030
inductive cell migration GO:0040039 145 0.030
gamete generation GO:0007276 461 0.030
hermaphrodite genitalia development GO:0040035 734 0.030
regulation of cell communication GO:0010646 176 0.029
regulation of response to stimulus GO:0048583 243 0.029
phagocytosis engulfment GO:0006911 98 0.029
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.029
digestive system development GO:0055123 122 0.029
taxis GO:0042330 128 0.029
protein modification process GO:0036211 207 0.028
tissue development GO:0009888 112 0.028
organic substance biosynthetic process GO:1901576 323 0.028
receptor mediated endocytosis GO:0006898 715 0.028
membrane invagination GO:0010324 98 0.028
neurogenesis GO:0022008 236 0.028
regulation of localization GO:0032879 194 0.028
cellular nitrogen compound catabolic process GO:0044270 119 0.028
regulation of cellular component movement GO:0051270 62 0.027
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.027
positive regulation of nucleic acid templated transcription GO:1903508 102 0.026
ion transmembrane transport GO:0034220 91 0.025
regulation of protein metabolic process GO:0051246 81 0.025
negative regulation of macromolecule metabolic process GO:0010605 229 0.025
cellular component morphogenesis GO:0032989 318 0.025
response to wounding GO:0009611 4 0.025
neuron differentiation GO:0030182 217 0.025
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.025
organophosphate metabolic process GO:0019637 125 0.025
mitotic cell cycle process GO:1903047 194 0.024
nucleoside metabolic process GO:0009116 99 0.024
mitotic nuclear division GO:0007067 89 0.024
response to acid chemical GO:0001101 4 0.024
regulation of signal transduction GO:0009966 135 0.024
apoptotic cell clearance GO:0043277 111 0.023
regulation of macromolecule biosynthetic process GO:0010556 189 0.023
cellular macromolecule biosynthetic process GO:0034645 247 0.023
cell fate commitment GO:0045165 139 0.023
protein complex assembly GO:0006461 186 0.023
tube development GO:0035295 126 0.023
ribonucleotide metabolic process GO:0009259 99 0.022
negative regulation of metabolic process GO:0009892 240 0.022
muscle contraction GO:0006936 43 0.022
post embryonic organ development GO:0048569 336 0.022
purine nucleotide catabolic process GO:0006195 75 0.022
enzyme linked receptor protein signaling pathway GO:0007167 50 0.022
positive regulation of rna biosynthetic process GO:1902680 102 0.022
meiotic nuclear division GO:0007126 300 0.022
regulation of metabolic process GO:0019222 478 0.022
actomyosin structure organization GO:0031032 154 0.022
cellular protein modification process GO:0006464 207 0.022
nucleobase containing small molecule metabolic process GO:0055086 115 0.022
cell type specific apoptotic process GO:0097285 4 0.022
purine nucleoside metabolic process GO:0042278 92 0.022
regulation of system process GO:0044057 27 0.022
small molecule metabolic process GO:0044281 186 0.021
striated muscle myosin thick filament assembly GO:0071688 138 0.021
regulation of muscle system process GO:0090257 20 0.021
female gamete generation GO:0007292 254 0.021
nucleotide metabolic process GO:0009117 108 0.021
protein catabolic process GO:0030163 162 0.021
nucleoside phosphate metabolic process GO:0006753 108 0.021
ribonucleoside metabolic process GO:0009119 98 0.021
germ cell development GO:0007281 351 0.021
organic substance transport GO:0071702 113 0.021
protein localization GO:0008104 205 0.021
single organism biosynthetic process GO:0044711 91 0.021
feeding behavior GO:0007631 70 0.020
cellular macromolecular complex assembly GO:0034622 184 0.020
cellular protein metabolic process GO:0044267 279 0.020
ribonucleoside monophosphate metabolic process GO:0009161 45 0.020
regulation of cell motility GO:2000145 57 0.020
membrane organization GO:0061024 135 0.020
positive regulation of cellular biosynthetic process GO:0031328 109 0.019
myosin filament assembly GO:0031034 138 0.019
macromolecule modification GO:0043412 218 0.019
myosin filament organization GO:0031033 138 0.019
embryonic morphogenesis GO:0048598 152 0.019
myofibril assembly GO:0030239 154 0.019
small molecule biosynthetic process GO:0044283 38 0.019
organonitrogen compound biosynthetic process GO:1901566 44 0.019
localization within membrane GO:0051668 2 0.019
purine containing compound metabolic process GO:0072521 95 0.019
protein complex biogenesis GO:0070271 186 0.019
organic acid metabolic process GO:0006082 47 0.018
positive regulation of cell migration GO:0030335 3 0.018
engulfment of apoptotic cell GO:0043652 94 0.018
actin cytoskeleton organization GO:0030036 184 0.018
generation of neurons GO:0048699 235 0.018
vulval development GO:0040025 333 0.018
protein oligomerization GO:0051259 4 0.018
cytokinesis GO:0000910 80 0.018
defense response GO:0006952 296 0.018
cellular response to abiotic stimulus GO:0071214 4 0.018
macromolecular complex subunit organization GO:0043933 320 0.018
cellular amine metabolic process GO:0044106 15 0.017
macromolecular complex assembly GO:0065003 193 0.017
uterus morphogenesis GO:0061038 2 0.017
epithelial cell proliferation GO:0050673 1 0.017
anion transport GO:0006820 30 0.017
cellular response to stress GO:0033554 162 0.017
Worm
immune response GO:0006955 192 0.017
regulation of nitrogen compound metabolic process GO:0051171 222 0.016
positive regulation of cellular metabolic process GO:0031325 178 0.016
sensory organ morphogenesis GO:0090596 2 0.016
phosphorylation GO:0016310 116 0.016
posttranscriptional regulation of gene expression GO:0010608 166 0.016
response to oxygen containing compound GO:1901700 44 0.016
homeostatic process GO:0042592 51 0.016
establishment or maintenance of cell polarity GO:0007163 63 0.016
negative regulation of response to stimulus GO:0048585 73 0.016
regulation of cellular protein metabolic process GO:0032268 75 0.016
embryonic body morphogenesis GO:0010172 49 0.015
purine ribonucleotide metabolic process GO:0009150 95 0.015
head development GO:0060322 1 0.015
purine nucleotide metabolic process GO:0006163 95 0.015
dauer larval development GO:0040024 92 0.015
digestive tract development GO:0048565 122 0.015
carbohydrate derivative metabolic process GO:1901135 141 0.015
secretion by cell GO:0032940 138 0.015
regulation of gene expression epigenetic GO:0040029 163 0.015
cellular catabolic process GO:0044248 199 0.015
regulation of organelle organization GO:0033043 164 0.015
aromatic compound catabolic process GO:0019439 116 0.015
collagen and cuticulin based cuticle development GO:0040002 99 0.015
single organism catabolic process GO:0044712 129 0.015
intracellular signal transduction GO:0035556 96 0.014
regulation of cellular metabolic process GO:0031323 305 0.014
neuron projection development GO:0031175 187 0.014
regeneration GO:0031099 4 0.014
negative regulation of gene expression epigenetic GO:0045814 2 0.014
muscle fiber development GO:0048747 2 0.014
positive regulation of macromolecule metabolic process GO:0010604 149 0.014
organic cyclic compound catabolic process GO:1901361 119 0.014
regulation of behavior GO:0050795 97 0.014
regulation of catalytic activity GO:0050790 78 0.014
tissue morphogenesis GO:0048729 65 0.014
positive regulation of gene expression GO:0010628 112 0.013
dna metabolic process GO:0006259 74 0.013
regulation of cell proliferation GO:0042127 105 0.013
glycosyl compound metabolic process GO:1901657 100 0.013
purine nucleoside triphosphate metabolic process GO:0009144 87 0.013
carboxylic acid metabolic process GO:0019752 34 0.013
secretion GO:0046903 147 0.013
carboxylic acid catabolic process GO:0046395 3 0.013
nucleoside triphosphate metabolic process GO:0009141 87 0.013
purine ribonucleoside catabolic process GO:0046130 75 0.013
rrna metabolic process GO:0016072 3 0.013
neurological system process GO:0050877 53 0.013
er nucleus signaling pathway GO:0006984 66 0.012
Worm
negative regulation of biosynthetic process GO:0009890 65 0.012
positive regulation of biosynthetic process GO:0009891 109 0.012
cellular protein complex assembly GO:0043623 178 0.012
positive regulation of metabolic process GO:0009893 187 0.012
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.012
oxoacid metabolic process GO:0043436 47 0.012
gene silencing GO:0016458 143 0.012
canonical wnt signaling pathway GO:0060070 3 0.012
regulation of biosynthetic process GO:0009889 189 0.012
neuron recognition GO:0008038 83 0.012
deoxyribonucleotide metabolic process GO:0009262 2 0.012
cell proliferation GO:0008283 116 0.012
cellular amino acid metabolic process GO:0006520 15 0.012
cell projection organization GO:0030030 231 0.012
response to external stimulus GO:0009605 289 0.012
negative regulation of signaling GO:0023057 61 0.011
positive regulation of transcription dna templated GO:0045893 102 0.011
bmp signaling pathway GO:0030509 3 0.011
sarcomere organization GO:0045214 10 0.011
ribose phosphate metabolic process GO:0019693 99 0.011
cellular ketone metabolic process GO:0042180 14 0.011
protein phosphorylation GO:0006468 85 0.011
positive regulation of phosphorus metabolic process GO:0010562 56 0.011
nucleoside phosphate catabolic process GO:1901292 77 0.011
regulation of cellular ketone metabolic process GO:0010565 3 0.011
regulation of muscle contraction GO:0006937 20 0.011
defense response to bacterium GO:0042742 86 0.011
cuticle development GO:0042335 100 0.011
carbohydrate derivative catabolic process GO:1901136 82 0.011
negative regulation of multicellular organismal process GO:0051241 236 0.011
negative regulation of neurogenesis GO:0050768 4 0.011
adult locomotory behavior GO:0008344 1 0.011
response to temperature stimulus GO:0009266 66 0.011
organonitrogen compound catabolic process GO:1901565 90 0.011
negative regulation of rna metabolic process GO:0051253 53 0.010
negative regulation of neuron differentiation GO:0045665 4 0.010
regulation of response to wounding GO:1903034 1 0.010
nucleus localization GO:0051647 55 0.010
positive regulation of transcription from rna polymerase ii promoter involved in defense response to fungus GO:1901244 1 0.010
cellular response to nitrogen compound GO:1901699 24 0.010
regulation of molecular function GO:0065009 89 0.010

lec-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
cardiovascular system disease DOID:1287 0 0.018
nervous system disease DOID:863 0 0.015
lipodystrophy DOID:811 0 0.010
skin disease DOID:37 0 0.010
integumentary system disease DOID:16 0 0.010
myopathy DOID:423 0 0.010
congenital muscular dystrophy DOID:0050557 0 0.010
muscular disease DOID:0080000 0 0.010
muscular dystrophy DOID:9884 0 0.010
musculoskeletal system disease DOID:17 0 0.010
muscle tissue disease DOID:66 0 0.010