Caenorhabditis elegans

10 known processes

pir-1 (CELE_T23G7.5)

Protein PIR-1

pir-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.745
sex differentiation GO:0007548 909 0.724
reproductive structure development GO:0048608 850 0.486
establishment of localization GO:0051234 1171 0.441
embryo development GO:0009790 3052 0.418
hermaphrodite genitalia development GO:0040035 734 0.365
single organism reproductive process GO:0044702 1196 0.327
developmental process involved in reproduction GO:0003006 1165 0.318
endocytosis GO:0006897 819 0.291
organelle organization GO:0006996 783 0.276
reproductive system development GO:0061458 850 0.249
regulation of macromolecule metabolic process GO:0060255 421 0.226
gonad development GO:0008406 840 0.209
organ development GO:0048513 1102 0.201
genitalia development GO:0048806 741 0.192
regulation of multicellular organismal process GO:0051239 726 0.189
macromolecule localization GO:0033036 771 0.185
regulation of cellular biosynthetic process GO:0031326 189 0.184
transport GO:0006810 1093 0.178
rna metabolic process GO:0016070 228 0.173
Human
nucleic acid metabolic process GO:0090304 299 0.171
Human
nucleobase containing compound metabolic process GO:0006139 406 0.170
Human
single organism transport GO:0044765 447 0.124
macromolecule biosynthetic process GO:0009059 250 0.119
organic substance biosynthetic process GO:1901576 323 0.119
cellular macromolecule biosynthetic process GO:0034645 247 0.119
regulation of developmental process GO:0050793 684 0.112
negative regulation of biological process GO:0048519 567 0.110
post embryonic development GO:0009791 2152 0.108
regulation of biological quality GO:0065008 741 0.106
organelle fission GO:0048285 363 0.105
lipid localization GO:0010876 573 0.094
negative regulation of macromolecule metabolic process GO:0010605 229 0.092
single organism organelle organization GO:1902589 501 0.088
biosynthetic process GO:0009058 323 0.084
growth GO:0040007 562 0.083
ion transport GO:0006811 113 0.082
cell cycle GO:0007049 526 0.081
development of primary sexual characteristics GO:0045137 840 0.078
maintenance of location GO:0051235 580 0.072
neurogenesis GO:0022008 236 0.072
regulation of metabolic process GO:0019222 478 0.071
lipid storage GO:0019915 565 0.070
regulation of nitrogen compound metabolic process GO:0051171 222 0.070
receptor mediated endocytosis GO:0006898 715 0.068
neuron development GO:0048666 199 0.066
developmental growth GO:0048589 412 0.064
response to biotic stimulus GO:0009607 101 0.064
nervous system development GO:0007399 253 0.063
single organism localization GO:1902578 518 0.061
multicellular organismal aging GO:0010259 812 0.059
positive regulation of developmental process GO:0051094 408 0.059
cell development GO:0048468 696 0.058
apoptotic process GO:0006915 478 0.051
posttranscriptional regulation of gene expression GO:0010608 166 0.050
regulation of growth GO:0040008 409 0.048
gene expression GO:0010467 412 0.046
gene silencing GO:0016458 143 0.045
posttranscriptional gene silencing GO:0016441 143 0.045
positive regulation of multicellular organismal process GO:0051240 417 0.045
heterocycle biosynthetic process GO:0018130 187 0.045
multicellular organism reproduction GO:0032504 819 0.044
posttranscriptional gene silencing by rna GO:0035194 143 0.044
regulation of multicellular organismal development GO:2000026 317 0.043
meiotic nuclear division GO:0007126 300 0.043
neuron differentiation GO:0030182 217 0.041
positive regulation of cellular process GO:0048522 332 0.041
positive regulation of growth GO:0045927 369 0.041
vesicle mediated transport GO:0016192 852 0.040
multi organism reproductive process GO:0044703 867 0.040
determination of adult lifespan GO:0008340 812 0.040
signal transduction GO:0007165 317 0.039
sexual reproduction GO:0019953 546 0.039
multi multicellular organism process GO:0044706 390 0.038
establishment of localization in cell GO:0051649 318 0.037
multi organism behavior GO:0051705 389 0.037
multicellular organism growth GO:0035264 385 0.036
localization of cell GO:0051674 313 0.035
rna interference GO:0016246 137 0.035
protein localization GO:0008104 205 0.035
positive regulation of developmental growth GO:0048639 354 0.034
cellular biosynthetic process GO:0044249 315 0.034
response to external biotic stimulus GO:0043207 101 0.034
negative regulation of metabolic process GO:0009892 240 0.034
regulation of gene expression epigenetic GO:0040029 163 0.034
negative regulation of gene expression GO:0010629 217 0.034
regulation of multicellular organism growth GO:0040014 373 0.034
death GO:0016265 547 0.033
regulation of gene expression GO:0010468 366 0.032
behavior GO:0007610 527 0.032
post embryonic organ development GO:0048569 336 0.031
nucleobase containing compound biosynthetic process GO:0034654 184 0.031
multicellular organismal reproductive process GO:0048609 815 0.030
locomotion GO:0040011 1634 0.029
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.029
negative regulation of developmental process GO:0051093 227 0.029
aromatic compound biosynthetic process GO:0019438 192 0.029
aging GO:0007568 812 0.028
cellular component movement GO:0006928 388 0.028
cellular localization GO:0051641 360 0.028
body morphogenesis GO:0010171 620 0.028
meiotic cell cycle GO:0051321 335 0.027
multi organism reproductive behavior GO:0044705 387 0.026
neuron projection development GO:0031175 187 0.025
cellular protein metabolic process GO:0044267 279 0.025
regulation of developmental growth GO:0048638 389 0.025
germ cell development GO:0007281 351 0.025
cell cycle process GO:0022402 482 0.025
positive regulation of multicellular organism growth GO:0040018 352 0.024
inductive cell migration GO:0040039 145 0.024
multicellular organismal reproductive behavior GO:0033057 384 0.024
protein complex assembly GO:0006461 186 0.023
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.023
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.021
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.021
secretion GO:0046903 147 0.021
gamete generation GO:0007276 461 0.020
regulation of signaling GO:0023051 172 0.020
rna biosynthetic process GO:0032774 169 0.020
negative regulation of cellular process GO:0048523 239 0.020
negative regulation of multicellular organismal process GO:0051241 236 0.020
defense response GO:0006952 296 0.020
oviposition GO:0018991 364 0.020
response to chemical GO:0042221 356 0.020
regulation of primary metabolic process GO:0080090 292 0.020
gene silencing by rna GO:0031047 143 0.019
cell projection organization GO:0030030 231 0.019
response to external stimulus GO:0009605 289 0.019
regulation of axon regeneration GO:0048679 1 0.019
regulation of nematode larval development GO:0061062 260 0.018
single organism signaling GO:0044700 401 0.018
regulation of post embryonic development GO:0048580 260 0.018
axon development GO:0061564 163 0.018
reproductive behavior GO:0019098 387 0.018
cell migration GO:0016477 306 0.018
macromolecular complex subunit organization GO:0043933 320 0.018
signaling GO:0023052 401 0.017
regulation of rna metabolic process GO:0051252 173 0.017
transcription dna templated GO:0006351 168 0.017
positive regulation of cellular metabolic process GO:0031325 178 0.017
cell motility GO:0048870 313 0.017
regulation of organelle organization GO:0033043 164 0.017
mrna metabolic process GO:0016071 31 0.016
defense response to other organism GO:0098542 100 0.016
organic substance transport GO:0071702 113 0.016
negative regulation of response to dna damage stimulus GO:2001021 2 0.016
macromolecule catabolic process GO:0009057 202 0.016
female gamete generation GO:0007292 254 0.015
regulation of transport GO:0051049 91 0.015
dna metabolic process GO:0006259 74 0.015
regulation of macromolecule biosynthetic process GO:0010556 189 0.015
negative regulation of vulval development GO:0040027 206 0.015
feeding behavior GO:0007631 70 0.015
cellular macromolecule localization GO:0070727 75 0.015
regulation of cellular metabolic process GO:0031323 305 0.014
vulval development GO:0040025 333 0.014
meiotic chromosome segregation GO:0045132 139 0.014
macromolecular complex assembly GO:0065003 193 0.014
rna processing GO:0006396 34 0.013
cell proliferation GO:0008283 116 0.013
polynucleotide 5 dephosphorylation GO:0098507 1 0.013
Human
cellular response to stress GO:0033554 162 0.013
cell death GO:0008219 547 0.013
cell division GO:0051301 262 0.013
cellular component biogenesis GO:0044085 297 0.013
negative regulation of post embryonic development GO:0048581 208 0.012
nucleic acid templated transcription GO:0097659 169 0.012
regulation of biosynthetic process GO:0009889 189 0.012
regulation of transcription dna templated GO:0006355 164 0.012
secretion by cell GO:0032940 138 0.012
regulation of cellular component organization GO:0051128 248 0.012
regulation of intrinsic apoptotic signaling pathway GO:2001242 1 0.012
cell part morphogenesis GO:0032990 152 0.012
apoptotic cell clearance GO:0043277 111 0.011
mitotic nuclear envelope disassembly GO:0007077 2 0.011
regulation of vulval development GO:0040028 248 0.011
adult behavior GO:0030534 3 0.011
programmed cell death GO:0012501 500 0.011
cell projection morphogenesis GO:0048858 148 0.011
cellular component morphogenesis GO:0032989 318 0.011
negative regulation of gene expression epigenetic GO:0045814 2 0.011
regulation of localization GO:0032879 194 0.011
organic cyclic compound biosynthetic process GO:1901362 195 0.010
dna protection GO:0042262 2 0.010
cell surface receptor signaling pathway GO:0007166 149 0.010
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.010
chromosome segregation GO:0007059 180 0.010
protein catabolic process GO:0030163 162 0.010

pir-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
thyroid carcinoma DOID:3963 0 0.018
endocrine gland cancer DOID:170 0 0.018
thyroid cancer DOID:1781 0 0.018
cancer DOID:162 0 0.018
disease of cellular proliferation DOID:14566 0 0.018
organ system cancer DOID:0050686 0 0.018
prostate cancer DOID:10283 0 0.016
male reproductive organ cancer DOID:3856 0 0.016
reproductive organ cancer DOID:193 0 0.016