Caenorhabditis elegans

86 known processes

lin-3 (CELE_F36H1.4)

Protein LIN-3

lin-3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organ development GO:0048513 1102 0.951
reproductive structure development GO:0048608 850 0.854
genitalia development GO:0048806 741 0.834
single organism reproductive process GO:0044702 1196 0.710
embryo development GO:0009790 3052 0.689
hermaphrodite genitalia development GO:0040035 734 0.633
post embryonic development GO:0009791 2152 0.511
gonad development GO:0008406 840 0.459
development of primary sexual characteristics GO:0045137 840 0.458
post embryonic organ development GO:0048569 336 0.458
sex differentiation GO:0007548 909 0.442
developmental process involved in reproduction GO:0003006 1165 0.428
negative regulation of biological process GO:0048519 567 0.415
reproductive system development GO:0061458 850 0.408
regulation of macromolecule metabolic process GO:0060255 421 0.387
vulval development GO:0040025 333 0.382
regulation of macromolecule biosynthetic process GO:0010556 189 0.365
regulation of metabolic process GO:0019222 478 0.317
embryo development ending in birth or egg hatching GO:0009792 2992 0.270
single organism signaling GO:0044700 401 0.266
receptor mediated endocytosis GO:0006898 715 0.255
establishment of localization GO:0051234 1171 0.244
gene expression GO:0010467 412 0.210
catabolic process GO:0009056 318 0.209
gamete generation GO:0007276 461 0.206
endocytosis GO:0006897 819 0.204
tube development GO:0035295 126 0.203
organelle organization GO:0006996 783 0.190
protein catabolic process GO:0030163 162 0.186
neuron projection development GO:0031175 187 0.185
digestive tract morphogenesis GO:0048546 76 0.182
multicellular organismal reproductive process GO:0048609 815 0.181
macromolecule catabolic process GO:0009057 202 0.179
positive regulation of macromolecule metabolic process GO:0010604 149 0.170
transcription dna templated GO:0006351 168 0.170
locomotion GO:0040011 1634 0.166
positive regulation of rna metabolic process GO:0051254 103 0.162
regulation of cell cycle GO:0051726 194 0.162
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.159
multicellular organismal reproductive behavior GO:0033057 384 0.158
negative regulation of cellular process GO:0048523 239 0.157
body morphogenesis GO:0010171 620 0.149
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.148
multicellular organism reproduction GO:0032504 819 0.144
regulation of gene expression GO:0010468 366 0.141
cell cell signaling GO:0007267 118 0.133
single organism organelle organization GO:1902589 501 0.130
programmed cell death GO:0012501 500 0.124
digestive tract development GO:0048565 122 0.123
regulation of multicellular organismal development GO:2000026 317 0.120
mitotic cell cycle process GO:1903047 194 0.120
cell migration GO:0016477 306 0.120
regulation of rna metabolic process GO:0051252 173 0.119
multi organism reproductive process GO:0044703 867 0.117
protein metabolic process GO:0019538 422 0.115
transport GO:0006810 1093 0.112
nucleic acid templated transcription GO:0097659 169 0.112
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.110
sexual reproduction GO:0019953 546 0.109
death GO:0016265 547 0.108
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.108
signal transduction GO:0007165 317 0.106
cellular macromolecule biosynthetic process GO:0034645 247 0.106
biosynthetic process GO:0009058 323 0.105
cell death GO:0008219 547 0.105
regulation of developmental process GO:0050793 684 0.104
tissue morphogenesis GO:0048729 65 0.103
regulation of signaling GO:0023051 172 0.102
growth GO:0040007 562 0.101
cell motility GO:0048870 313 0.099
regulation of nematode larval development GO:0061062 260 0.098
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.097
negative regulation of vulval development GO:0040027 206 0.095
aging GO:0007568 812 0.095
macromolecule modification GO:0043412 218 0.095
negative regulation of cell cycle GO:0045786 53 0.094
embryonic morphogenesis GO:0048598 152 0.093
aromatic compound biosynthetic process GO:0019438 192 0.093
embryonic pattern specification GO:0009880 21 0.092
determination of adult lifespan GO:0008340 812 0.092
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.089
regulation of cell cycle process GO:0010564 145 0.088
phosphorylation GO:0016310 116 0.087
cellular biosynthetic process GO:0044249 315 0.087
cellular protein modification process GO:0006464 207 0.086
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.086
transcription from rna polymerase ii promoter GO:0006366 149 0.086
germ cell development GO:0007281 351 0.085
organic substance biosynthetic process GO:1901576 323 0.085
cell projection organization GO:0030030 231 0.085
gene silencing GO:0016458 143 0.083
tissue development GO:0009888 112 0.083
localization of cell GO:0051674 313 0.083
phosphate containing compound metabolic process GO:0006796 232 0.083
organic substance catabolic process GO:1901575 294 0.083
establishment of organelle localization GO:0051656 123 0.082
regulation of response to stimulus GO:0048583 243 0.081
negative regulation of developmental process GO:0051093 227 0.081
negative regulation of gene expression GO:0010629 217 0.081
cell cycle phase transition GO:0044770 19 0.080
macromolecule localization GO:0033036 771 0.080
macromolecule biosynthetic process GO:0009059 250 0.079
regulation of cell communication GO:0010646 176 0.079
neuron differentiation GO:0030182 217 0.077
rna metabolic process GO:0016070 228 0.077
cell development GO:0048468 696 0.077
regulation of rna biosynthetic process GO:2001141 165 0.076
cell morphogenesis GO:0000902 163 0.076
digestive system development GO:0055123 122 0.076
positive regulation of transcription dna templated GO:0045893 102 0.075
regulation of cellular biosynthetic process GO:0031326 189 0.075
regulation of multicellular organism growth GO:0040014 373 0.074
positive regulation of cellular metabolic process GO:0031325 178 0.072
cellular component morphogenesis GO:0032989 318 0.071
regulation of transcription dna templated GO:0006355 164 0.070
regulation of vulval development GO:0040028 248 0.069
epithelium development GO:0060429 68 0.068
signaling GO:0023052 401 0.068
developmental growth GO:0048589 412 0.068
cell cycle process GO:0022402 482 0.068
positive regulation of developmental growth GO:0048639 354 0.065
generation of neurons GO:0048699 235 0.064
protein modification process GO:0036211 207 0.064
multicellular organismal aging GO:0010259 812 0.062
rna biosynthetic process GO:0032774 169 0.062
negative regulation of signaling GO:0023057 61 0.061
regulation of post embryonic development GO:0048580 260 0.060
cellular protein metabolic process GO:0044267 279 0.060
cell morphogenesis involved in differentiation GO:0000904 112 0.059
single organism behavior GO:0044708 83 0.058
regulation of primary metabolic process GO:0080090 292 0.058
positive regulation of developmental process GO:0051094 408 0.057
positive regulation of gene expression GO:0010628 112 0.057
protein phosphorylation GO:0006468 85 0.056
gastrulation GO:0007369 58 0.056
tube morphogenesis GO:0035239 79 0.056
regulation of gene expression epigenetic GO:0040029 163 0.055
vesicle mediated transport GO:0016192 852 0.055
nervous system development GO:0007399 253 0.054
positive regulation of growth GO:0045927 369 0.054
regulation of cellular metabolic process GO:0031323 305 0.054
nucleobase containing compound metabolic process GO:0006139 406 0.054
cell fate commitment GO:0045165 139 0.053
response to external stimulus GO:0009605 289 0.052
intracellular signal transduction GO:0035556 96 0.052
cell surface receptor signaling pathway GO:0007166 149 0.052
positive regulation of cellular biosynthetic process GO:0031328 109 0.052
behavior GO:0007610 527 0.049
response to organic substance GO:0010033 131 0.049
ubiquitin dependent protein catabolic process GO:0006511 32 0.049
muscle system process GO:0003012 43 0.049
cellular catabolic process GO:0044248 199 0.048
pattern specification process GO:0007389 59 0.048
negative regulation of post embryonic development GO:0048581 208 0.047
regulation of multicellular organismal process GO:0051239 726 0.047
taxis GO:0042330 128 0.047
cytoskeleton organization GO:0007010 339 0.046
positive regulation of metabolic process GO:0009893 187 0.046
positive regulation of rna biosynthetic process GO:1902680 102 0.046
cell cycle GO:0007049 526 0.046
lipid storage GO:0019915 565 0.045
meiotic nuclear division GO:0007126 300 0.045
organelle assembly GO:0070925 214 0.045
response to growth factor GO:0070848 18 0.044
nucleic acid metabolic process GO:0090304 299 0.044
organelle localization GO:0051640 127 0.044
single organism localization GO:1902578 518 0.044
positive regulation of locomotion GO:0040017 42 0.043
oviposition GO:0018991 364 0.043
enzyme linked receptor protein signaling pathway GO:0007167 50 0.043
negative regulation of response to stimulus GO:0048585 73 0.043
maintenance of location GO:0051235 580 0.043
macromolecular complex assembly GO:0065003 193 0.043
meiotic cell cycle GO:0051321 335 0.042
positive regulation of multicellular organismal process GO:0051240 417 0.042
phosphorus metabolic process GO:0006793 232 0.042
heterocycle biosynthetic process GO:0018130 187 0.042
lipid localization GO:0010876 573 0.042
organelle fission GO:0048285 363 0.041
regulation of signal transduction GO:0009966 135 0.041
positive regulation of biosynthetic process GO:0009891 109 0.041
positive regulation of nucleic acid templated transcription GO:1903508 102 0.040
protein complex subunit organization GO:0071822 280 0.040
regulation of cellular component organization GO:0051128 248 0.039
negative regulation of cell communication GO:0010648 61 0.039
head development GO:0060322 1 0.038
regulation of biological quality GO:0065008 741 0.038
organic cyclic compound biosynthetic process GO:1901362 195 0.037
regulation of synaptic transmission GO:0050804 34 0.036
apoptotic process GO:0006915 478 0.036
epithelial tube morphogenesis GO:0060562 1 0.036
regulation of mitotic cell cycle GO:0007346 76 0.036
regulation of nitrogen compound metabolic process GO:0051171 222 0.036
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.036
reproductive behavior GO:0019098 387 0.035
response to chemical GO:0042221 356 0.035
cellular localization GO:0051641 360 0.035
regulation of meiotic cell cycle GO:0051445 136 0.035
positive regulation of multicellular organism growth GO:0040018 352 0.035
anterior posterior axis specification GO:0009948 17 0.035
positive regulation of cell migration GO:0030335 3 0.035
neuron development GO:0048666 199 0.035
multi multicellular organism process GO:0044706 390 0.035
positive regulation of neurogenesis GO:0050769 4 0.034
microtubule based process GO:0007017 182 0.034
negative regulation of macromolecule metabolic process GO:0010605 229 0.033
negative regulation of metabolic process GO:0009892 240 0.033
embryonic body morphogenesis GO:0010172 49 0.033
negative regulation of multicellular organismal process GO:0051241 236 0.033
regulation of nuclear division GO:0051783 115 0.032
meiotic cell cycle process GO:1903046 170 0.032
aminoglycan biosynthetic process GO:0006023 5 0.032
single organism biosynthetic process GO:0044711 91 0.032
cellular response to organic substance GO:0071310 119 0.032
cellular response to stress GO:0033554 162 0.031
multicellular organism growth GO:0035264 385 0.031
sensory organ morphogenesis GO:0090596 2 0.031
gene silencing by rna GO:0031047 143 0.031
negative regulation of nematode larval development GO:0061064 208 0.030
posttranscriptional gene silencing GO:0016441 143 0.030
regulation of phosphorus metabolic process GO:0051174 81 0.030
regulation of growth GO:0040008 409 0.029
oocyte construction GO:0007308 2 0.029
negative regulation of signal transduction GO:0009968 60 0.029
cellular component movement GO:0006928 388 0.028
positive regulation of cellular process GO:0048522 332 0.028
regulation of protein metabolic process GO:0051246 81 0.028
rna interference GO:0016246 137 0.028
striated muscle cell differentiation GO:0051146 158 0.028
regulation of cell fate commitment GO:0010453 22 0.028
cell proliferation GO:0008283 116 0.028
positive regulation of cell cycle GO:0045787 55 0.027
multi organism behavior GO:0051705 389 0.027
nucleobase containing compound biosynthetic process GO:0034654 184 0.027
spindle checkpoint GO:0031577 4 0.027
muscle contraction GO:0006936 43 0.027
long term memory GO:0007616 2 0.026
actin filament based process GO:0030029 191 0.026
neuron projection morphogenesis GO:0048812 114 0.026
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 20 0.026
cellular component biogenesis GO:0044085 297 0.026
cell projection morphogenesis GO:0048858 148 0.026
memory GO:0007613 3 0.026
cell division GO:0051301 262 0.025
regulation of nucleic acid templated transcription GO:1903506 165 0.025
regulation of developmental growth GO:0048638 389 0.025
oogenesis GO:0048477 229 0.025
multi organism reproductive behavior GO:0044705 387 0.025
proteolysis GO:0006508 61 0.025
regulation of biosynthetic process GO:0009889 189 0.025
neurological system process GO:0050877 53 0.025
regulation of cell development GO:0060284 49 0.024
actomyosin structure organization GO:0031032 154 0.024
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.024
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.024
neuron projection guidance GO:0097485 82 0.024
anatomical structure formation involved in morphogenesis GO:0048646 250 0.024
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.024
molting cycle GO:0042303 281 0.024
positive regulation of epithelial cell proliferation GO:0050679 1 0.024
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 16 0.023
cellular macromolecule catabolic process GO:0044265 73 0.023
regulation of synaptic plasticity GO:0048167 1 0.023
negative regulation of mitotic cell cycle GO:0045930 42 0.023
protein complex assembly GO:0006461 186 0.023
neurogenesis GO:0022008 236 0.022
system process GO:0003008 136 0.022
chemotaxis GO:0006935 120 0.022
regulation of cell division GO:0051302 142 0.022
positive regulation of vulval development GO:0040026 52 0.022
oocyte development GO:0048599 44 0.022
actin cytoskeleton organization GO:0030036 184 0.021
cellular macromolecular complex assembly GO:0034622 184 0.021
regulation of locomotion GO:0040012 161 0.021
cellular response to chemical stimulus GO:0070887 129 0.021
cell substrate adhesion GO:0031589 1 0.021
secretion GO:0046903 147 0.021
cellular component assembly GO:0022607 293 0.021
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.021
axon guidance GO:0007411 82 0.021
posttranscriptional gene silencing by rna GO:0035194 143 0.020
cellular protein complex assembly GO:0043623 178 0.020
macromolecular complex subunit organization GO:0043933 320 0.020
small molecule metabolic process GO:0044281 186 0.020
establishment of cell polarity GO:0030010 46 0.020
proteolysis involved in cellular protein catabolic process GO:0051603 32 0.020
oocyte differentiation GO:0009994 45 0.019
glycoprotein metabolic process GO:0009100 29 0.019
response to abiotic stimulus GO:0009628 152 0.019
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.019
cellular component assembly involved in morphogenesis GO:0010927 183 0.019
negative regulation of biosynthetic process GO:0009890 65 0.018
learning or memory GO:0007611 27 0.018
mitotic nuclear division GO:0007067 89 0.018
cellular nitrogen compound biosynthetic process GO:0044271 192 0.018
negative regulation of transcription dna templated GO:0045892 53 0.018
protein complex biogenesis GO:0070271 186 0.017
positive regulation of post embryonic development GO:0048582 54 0.017
axon development GO:0061564 163 0.017
striated muscle myosin thick filament assembly GO:0071688 138 0.017
adult behavior GO:0030534 3 0.016
defense response GO:0006952 296 0.016
stem cell division GO:0017145 18 0.016
single organism catabolic process GO:0044712 129 0.016
asymmetric stem cell division GO:0098722 8 0.016
myosin filament organization GO:0031033 138 0.016
sensory perception GO:0007600 27 0.015
cuticle development GO:0042335 100 0.015
organism emergence from protective structure GO:0071684 48 0.015
regulation of molecular function GO:0065009 89 0.015
response to wounding GO:0009611 4 0.015
organonitrogen compound metabolic process GO:1901564 151 0.015
regulation of cellular ketone metabolic process GO:0010565 3 0.015
regulation of cell migration GO:0030334 55 0.015
mitotic cell cycle phase transition GO:0044772 13 0.015
cellular water homeostasis GO:0009992 1 0.014
negative regulation of cellular biosynthetic process GO:0031327 65 0.014
regulation of localization GO:0032879 194 0.014
regulation of phosphorylation GO:0042325 45 0.014
positive regulation of response to stimulus GO:0048584 55 0.014
striated muscle cell development GO:0055002 157 0.014
negative regulation of nucleic acid templated transcription GO:1903507 53 0.014
collagen and cuticulin based cuticle development GO:0040002 99 0.014
regulation of cell motility GO:2000145 57 0.014
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.014
single organism transport GO:0044765 447 0.014
cellular protein catabolic process GO:0044257 37 0.014
regulation of cell death GO:0010941 65 0.013
mitotic nuclear envelope reassembly GO:0007084 3 0.013
regulation of organ morphogenesis GO:2000027 4 0.013
muscle cell development GO:0055001 158 0.013
negative regulation of ion transmembrane transport GO:0034766 3 0.013
myosin filament assembly GO:0031034 138 0.013
peptidyl lysine trimethylation GO:0018023 2 0.013
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.013
posttranscriptional regulation of gene expression GO:0010608 166 0.013
establishment or maintenance of cell polarity GO:0007163 63 0.013
myofibril assembly GO:0030239 154 0.013
negative regulation of neurogenesis GO:0050768 4 0.012
adult locomotory behavior GO:0008344 1 0.012
ras protein signal transduction GO:0007265 31 0.012
organic acid metabolic process GO:0006082 47 0.012
cell part morphogenesis GO:0032990 152 0.012
small gtpase mediated signal transduction GO:0007264 32 0.012
cell volume homeostasis GO:0006884 1 0.012
regulation of cell proliferation GO:0042127 105 0.012
positive regulation of phosphorus metabolic process GO:0010562 56 0.012
positive regulation of nematode larval development GO:0061063 54 0.012
anterior posterior pattern specification GO:0009952 27 0.012
hatching GO:0035188 48 0.012
oocyte axis specification GO:0007309 2 0.012
nematode male tail tip morphogenesis GO:0045138 77 0.011
developmental maturation GO:0021700 26 0.011
lipid metabolic process GO:0006629 77 0.011
organic cyclic compound catabolic process GO:1901361 119 0.011
cognition GO:0050890 27 0.011
response to acid chemical GO:0001101 4 0.011
regulation of epithelial cell proliferation GO:0050678 1 0.011
ion transmembrane transport GO:0034220 91 0.011
homeostatic process GO:0042592 51 0.011
regulation of cell morphogenesis GO:0022604 40 0.011
ovulation GO:0030728 33 0.011
regulation of ras protein signal transduction GO:0046578 41 0.011
pharynx development GO:0060465 51 0.011
protein localization GO:0008104 205 0.011
establishment of localization in cell GO:0051649 318 0.011
regulation of cell differentiation GO:0045595 81 0.011
neuroblast division GO:0055057 9 0.011
cell maturation GO:0048469 26 0.011
positive regulation of phosphorylation GO:0042327 27 0.011
inactivation of mapkkk activity GO:0051390 2 0.011
chromatin remodeling GO:0006338 2 0.011
organonitrogen compound catabolic process GO:1901565 90 0.010
nucleobase containing small molecule metabolic process GO:0055086 115 0.010
synaptic transmission GO:0007268 106 0.010
positive regulation of transcription from rna polymerase ii promoter in response to stress GO:0036003 2 0.010
regulation of cellular protein metabolic process GO:0032268 75 0.010
negative regulation of rna metabolic process GO:0051253 53 0.010
mucopolysaccharide metabolic process GO:1903510 4 0.010
chromosome organization GO:0051276 104 0.010

lin-3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.016
muscular disease DOID:0080000 0 0.016
heart disease DOID:114 0 0.016
cardiomyopathy DOID:0050700 0 0.016
disease of anatomical entity DOID:7 0 0.016
cardiovascular system disease DOID:1287 0 0.016
musculoskeletal system disease DOID:17 0 0.016
muscle tissue disease DOID:66 0 0.016