Caenorhabditis elegans

44 known processes

pri-2 (CELE_W02D9.1)

Protein PRI-2

pri-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.763
mitotic sister chromatid segregation GO:0000070 38 0.596
negative regulation of biological process GO:0048519 567 0.540
regulation of metabolic process GO:0019222 478 0.507
organic substance catabolic process GO:1901575 294 0.498
regulation of cell cycle process GO:0010564 145 0.424
regulation of macromolecule metabolic process GO:0060255 421 0.414
meiotic nuclear division GO:0007126 300 0.411
catabolic process GO:0009056 318 0.351
regulation of gene expression GO:0010468 366 0.344
germ cell development GO:0007281 351 0.342
cellular biosynthetic process GO:0044249 315 0.337
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.329
sexual reproduction GO:0019953 546 0.327
chromosome segregation GO:0007059 180 0.321
developmental process involved in reproduction GO:0003006 1165 0.313
negative regulation of gene expression GO:0010629 217 0.312
regulation of nucleic acid templated transcription GO:1903506 165 0.300
oogenesis GO:0048477 229 0.288
regulation of macromolecule biosynthetic process GO:0010556 189 0.284
multicellular organismal reproductive process GO:0048609 815 0.278
single organism organelle organization GO:1902589 501 0.272
cell cycle GO:0007049 526 0.267
cellular macromolecule biosynthetic process GO:0034645 247 0.256
embryo development ending in birth or egg hatching GO:0009792 2992 0.253
female gamete generation GO:0007292 254 0.234
cellular catabolic process GO:0044248 199 0.233
gamete generation GO:0007276 461 0.232
single organism reproductive process GO:0044702 1196 0.229
rna metabolic process GO:0016070 228 0.221
meiotic chromosome segregation GO:0045132 139 0.216
regulation of rna biosynthetic process GO:2001141 165 0.209
transport GO:0006810 1093 0.204
nucleobase containing compound metabolic process GO:0006139 406 0.203
regulation of cell division GO:0051302 142 0.176
nucleic acid metabolic process GO:0090304 299 0.171
death GO:0016265 547 0.167
cell cycle process GO:0022402 482 0.167
macromolecule biosynthetic process GO:0009059 250 0.167
negative regulation of metabolic process GO:0009892 240 0.159
regulation of transcription dna templated GO:0006355 164 0.150
multi organism reproductive process GO:0044703 867 0.146
protein complex subunit organization GO:0071822 280 0.145
regulation of meiotic cell cycle GO:0051445 136 0.143
regulation of mitotic cell cycle GO:0007346 76 0.139
multicellular organism reproduction GO:0032504 819 0.138
negative regulation of developmental process GO:0051093 227 0.134
organelle fission GO:0048285 363 0.128
establishment of localization GO:0051234 1171 0.126
sister chromatid segregation GO:0000819 46 0.124
post embryonic development GO:0009791 2152 0.121
regulation of rna metabolic process GO:0051252 173 0.121
organelle organization GO:0006996 783 0.113
reproductive system development GO:0061458 850 0.113
negative regulation of chromosome segregation GO:0051985 4 0.110
cellular nitrogen compound catabolic process GO:0044270 119 0.109
regulation of organelle organization GO:0033043 164 0.106
oocyte development GO:0048599 44 0.105
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.104
cellular nitrogen compound biosynthetic process GO:0044271 192 0.104
dna metabolic process GO:0006259 74 0.102
mitotic cell cycle process GO:1903047 194 0.101
cellular component assembly GO:0022607 293 0.101
cell development GO:0048468 696 0.100
meiotic cell cycle process GO:1903046 170 0.100
cellular response to dna damage stimulus GO:0006974 41 0.100
negative regulation of cellular process GO:0048523 239 0.097
microtubule anchoring GO:0034453 8 0.095
regulation of primary metabolic process GO:0080090 292 0.095
negative regulation of macromolecule metabolic process GO:0010605 229 0.095
protein catabolic process GO:0030163 162 0.094
organic cyclic compound biosynthetic process GO:1901362 195 0.093
macromolecule localization GO:0033036 771 0.089
vesicle mediated transport GO:0016192 852 0.087
regulation of vulval development GO:0040028 248 0.085
protein localization GO:0008104 205 0.085
biosynthetic process GO:0009058 323 0.085
aromatic compound catabolic process GO:0019439 116 0.084
meiotic cell cycle GO:0051321 335 0.084
regulation of cellular biosynthetic process GO:0031326 189 0.083
vulval development GO:0040025 333 0.082
regulation of cell cycle GO:0051726 194 0.082
regulation of developmental process GO:0050793 684 0.081
multicellular organismal aging GO:0010259 812 0.079
regulation of meiosis GO:0040020 94 0.079
single organism catabolic process GO:0044712 129 0.079
gene expression GO:0010467 412 0.079
modification dependent protein catabolic process GO:0019941 32 0.077
positive regulation of cellular process GO:0048522 332 0.077
phosphate containing compound metabolic process GO:0006796 232 0.077
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.077
chromosome organization GO:0051276 104 0.076
mrna metabolic process GO:0016071 31 0.076
transcription from rna polymerase ii promoter GO:0006366 149 0.076
regulation of cellular metabolic process GO:0031323 305 0.075
apoptotic process GO:0006915 478 0.074
programmed cell death GO:0012501 500 0.074
reproductive structure development GO:0048608 850 0.072
regulation of multicellular organismal development GO:2000026 317 0.071
phosphorus metabolic process GO:0006793 232 0.071
oocyte differentiation GO:0009994 45 0.071
response to chemical GO:0042221 356 0.070
macromolecular complex subunit organization GO:0043933 320 0.070
negative regulation of biosynthetic process GO:0009890 65 0.070
cellular macromolecular complex assembly GO:0034622 184 0.069
organic substance biosynthetic process GO:1901576 323 0.069
cell death GO:0008219 547 0.068
nucleic acid templated transcription GO:0097659 169 0.066
single organism signaling GO:0044700 401 0.066
determination of adult lifespan GO:0008340 812 0.066
mitotic nuclear division GO:0007067 89 0.065
hermaphrodite genitalia development GO:0040035 734 0.065
regulation of biological quality GO:0065008 741 0.065
gonad development GO:0008406 840 0.064
aging GO:0007568 812 0.064
positive regulation of metabolic process GO:0009893 187 0.062
regulation of biosynthetic process GO:0009889 189 0.062
maintenance of location GO:0051235 580 0.061
heterocycle biosynthetic process GO:0018130 187 0.060
positive regulation of rna metabolic process GO:0051254 103 0.060
heterocycle catabolic process GO:0046700 119 0.060
regulation of nematode larval development GO:0061062 260 0.059
neuron development GO:0048666 199 0.059
gene silencing GO:0016458 143 0.059
regulation of multicellular organismal process GO:0051239 726 0.058
transcription dna templated GO:0006351 168 0.057
cell part morphogenesis GO:0032990 152 0.056
cellular localization GO:0051641 360 0.056
cytoskeleton organization GO:0007010 339 0.055
regulation of nucleocytoplasmic transport GO:0046822 3 0.055
cell cell signaling GO:0007267 118 0.054
regulation of nuclear division GO:0051783 115 0.054
pattern specification process GO:0007389 59 0.054
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.053
regulation of mitotic metaphase anaphase transition GO:0030071 5 0.053
locomotion GO:0040011 1634 0.053
macromolecule catabolic process GO:0009057 202 0.053
regulation of cellular component organization GO:0051128 248 0.052
dna duplex unwinding GO:0032508 3 0.052
lipid storage GO:0019915 565 0.051
cellular protein catabolic process GO:0044257 37 0.050
lipid localization GO:0010876 573 0.048
spindle organization GO:0007051 92 0.047
growth GO:0040007 562 0.046
negative regulation of cell cycle GO:0045786 53 0.046
cellular response to stress GO:0033554 162 0.045
cell division GO:0051301 262 0.045
positive regulation of gene expression GO:0010628 112 0.045
ribonucleoside triphosphate metabolic process GO:0009199 87 0.045
positive regulation of macromolecule metabolic process GO:0010604 149 0.044
organic cyclic compound catabolic process GO:1901361 119 0.044
negative regulation of transcription dna templated GO:0045892 53 0.044
single organism localization GO:1902578 518 0.044
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.044
gene silencing by rna GO:0031047 143 0.044
cellular protein localization GO:0034613 75 0.044
purine nucleotide catabolic process GO:0006195 75 0.044
ribonucleotide metabolic process GO:0009259 99 0.043
regulation of chromosome organization GO:0033044 20 0.042
protein complex assembly GO:0006461 186 0.042
signal transduction GO:0007165 317 0.041
sex differentiation GO:0007548 909 0.041
negative regulation of nematode larval development GO:0061064 208 0.041
nervous system development GO:0007399 253 0.040
multi organism reproductive behavior GO:0044705 387 0.040
negative regulation of post embryonic development GO:0048581 208 0.040
post embryonic organ development GO:0048569 336 0.040
purine ribonucleotide metabolic process GO:0009150 95 0.040
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.040
neuron differentiation GO:0030182 217 0.039
regulation of developmental growth GO:0048638 389 0.039
nucleoside monophosphate metabolic process GO:0009123 46 0.038
behavior GO:0007610 527 0.037
spindle checkpoint GO:0031577 4 0.037
cell fate commitment GO:0045165 139 0.037
body morphogenesis GO:0010171 620 0.036
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.036
macromolecular complex assembly GO:0065003 193 0.035
negative regulation of cellular metabolic process GO:0031324 95 0.035
developmental growth GO:0048589 412 0.035
rna localization GO:0006403 3 0.035
positive regulation of neuron differentiation GO:0045666 4 0.034
glycosyl compound metabolic process GO:1901657 100 0.034
posttranscriptional regulation of gene expression GO:0010608 166 0.034
dna geometric change GO:0032392 3 0.034
oviposition GO:0018991 364 0.033
rna biosynthetic process GO:0032774 169 0.033
signaling GO:0023052 401 0.033
positive regulation of cellular biosynthetic process GO:0031328 109 0.032
neurogenesis GO:0022008 236 0.032
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.032
nucleoside catabolic process GO:0009164 78 0.031
cellular protein metabolic process GO:0044267 279 0.031
negative regulation of nucleic acid templated transcription GO:1903507 53 0.031
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.031
neuron projection development GO:0031175 187 0.031
ribonucleoside monophosphate metabolic process GO:0009161 45 0.031
organic substance transport GO:0071702 113 0.030
negative regulation of mitotic cell cycle GO:0045930 42 0.030
regulation of growth GO:0040008 409 0.030
negative regulation of cellular biosynthetic process GO:0031327 65 0.030
small molecule metabolic process GO:0044281 186 0.030
organophosphate metabolic process GO:0019637 125 0.029
negative regulation of rna biosynthetic process GO:1902679 53 0.029
establishment of localization in cell GO:0051649 318 0.029
multi organism behavior GO:0051705 389 0.028
purine nucleoside catabolic process GO:0006152 75 0.028
genitalia development GO:0048806 741 0.028
regulation of gene expression epigenetic GO:0040029 163 0.027
cellular component biogenesis GO:0044085 297 0.026
regulation of nitrogen compound metabolic process GO:0051171 222 0.025
protein complex biogenesis GO:0070271 186 0.024
anatomical structure formation involved in morphogenesis GO:0048646 250 0.024
nucleobase containing compound biosynthetic process GO:0034654 184 0.024
chromosome organization involved in meiosis GO:0070192 25 0.024
cell recognition GO:0008037 85 0.024
single organism transport GO:0044765 447 0.024
aromatic compound biosynthetic process GO:0019438 192 0.024
nucleobase containing compound catabolic process GO:0034655 114 0.023
multicellular organismal reproductive behavior GO:0033057 384 0.023
oocyte axis specification GO:0007309 2 0.023
negative regulation of mitotic metaphase anaphase transition GO:0045841 4 0.023
cuticle development GO:0042335 100 0.023
posttranscriptional gene silencing by rna GO:0035194 143 0.023
fertilization GO:0009566 63 0.023
dna conformation change GO:0071103 11 0.022
cell cycle phase transition GO:0044770 19 0.022
metaphase anaphase transition of mitotic cell cycle GO:0007091 10 0.022
purine ribonucleoside monophosphate metabolic process GO:0009167 43 0.022
attachment of spindle microtubules to kinetochore GO:0008608 8 0.022
positive regulation of transcription dna templated GO:0045893 102 0.022
peptidyl tyrosine phosphorylation GO:0018108 2 0.022
endocytosis GO:0006897 819 0.021
cell projection organization GO:0030030 231 0.021
regulation of response to stimulus GO:0048583 243 0.021
cellular response to organic substance GO:0071310 119 0.021
negative regulation of vulval development GO:0040027 206 0.021
ribose phosphate metabolic process GO:0019693 99 0.021
chromatin assembly or disassembly GO:0006333 1 0.021
proteasomal protein catabolic process GO:0010498 20 0.021
protein modification process GO:0036211 207 0.021
defense response GO:0006952 296 0.021
organ development GO:0048513 1102 0.021
single fertilization GO:0007338 61 0.021
response to organic substance GO:0010033 131 0.021
proteolysis GO:0006508 61 0.021
regulation of multicellular organism growth GO:0040014 373 0.021
ubiquitin dependent protein catabolic process GO:0006511 32 0.020
mitotic g2 m transition checkpoint GO:0044818 1 0.020
organelle assembly GO:0070925 214 0.020
ribonucleoside catabolic process GO:0042454 77 0.020
spermatogenesis GO:0007283 41 0.019
nucleobase containing small molecule metabolic process GO:0055086 115 0.019
positive regulation of signaling GO:0023056 66 0.019
chromatin organization GO:0006325 32 0.019
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.019
positive regulation of cellular metabolic process GO:0031325 178 0.019
regulation of chromosome segregation GO:0051983 20 0.019
posttranscriptional gene silencing GO:0016441 143 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 32 0.019
cellular macromolecule catabolic process GO:0044265 73 0.019
rna interference GO:0016246 137 0.019
response to external stimulus GO:0009605 289 0.019
oocyte construction GO:0007308 2 0.019
cell projection morphogenesis GO:0048858 148 0.018
receptor mediated endocytosis GO:0006898 715 0.018
development of primary sexual characteristics GO:0045137 840 0.018
regulation of cytoplasmic transport GO:1903649 3 0.018
cellular protein modification process GO:0006464 207 0.018
female meiotic division GO:0007143 17 0.018
positive regulation of developmental process GO:0051094 408 0.018
reproductive behavior GO:0019098 387 0.018
negative regulation of mitotic sister chromatid segregation GO:0033048 4 0.018
nucleoside triphosphate catabolic process GO:0009143 72 0.018
deoxyribonucleotide biosynthetic process GO:0009263 1 0.018
microtubule based process GO:0007017 182 0.018
negative regulation of proteasomal protein catabolic process GO:1901799 4 0.017
macromolecule modification GO:0043412 218 0.017
positive regulation of cell cycle GO:0045787 55 0.017
positive regulation of multicellular organism growth GO:0040018 352 0.017
meiosis i GO:0007127 19 0.017
male gamete generation GO:0048232 41 0.017
protein metabolic process GO:0019538 422 0.017
purine nucleoside monophosphate metabolic process GO:0009126 43 0.017
nucleoside phosphate metabolic process GO:0006753 108 0.017
sensory organ morphogenesis GO:0090596 2 0.017
nucleotide catabolic process GO:0009166 77 0.017
rna transport GO:0050658 3 0.017
purine containing compound catabolic process GO:0072523 75 0.016
regulation of sister chromatid segregation GO:0033045 16 0.016
mrna processing GO:0006397 13 0.016
negative regulation of rna metabolic process GO:0051253 53 0.016
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 10 0.016
molting cycle GO:0042303 281 0.016
positive regulation of multicellular organismal process GO:0051240 417 0.016
purine ribonucleotide catabolic process GO:0009154 75 0.016
regulation of catabolic process GO:0009894 57 0.016
regulation of molecular function GO:0065009 89 0.016
nucleotide metabolic process GO:0009117 108 0.016
actin filament based process GO:0030029 191 0.016
collagen and cuticulin based cuticle development GO:0040002 99 0.016
positive regulation of growth GO:0045927 369 0.015
purine nucleotide metabolic process GO:0006163 95 0.015
regulation of cellular ketone metabolic process GO:0010565 3 0.015
positive regulation of developmental growth GO:0048639 354 0.015
regulation of cellular catabolic process GO:0031329 51 0.015
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.015
nucleoside triphosphate metabolic process GO:0009141 87 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.015
multicellular organism growth GO:0035264 385 0.015
nucleic acid transport GO:0050657 3 0.015
negative regulation of translation GO:0017148 10 0.015
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.015
nucleoside metabolic process GO:0009116 99 0.014
organonitrogen compound metabolic process GO:1901564 151 0.014
pronuclear migration GO:0035046 51 0.014
positive regulation of nucleic acid templated transcription GO:1903508 102 0.014
cellular macromolecule localization GO:0070727 75 0.014
mitotic spindle organization GO:0007052 81 0.014
cellular response to abiotic stimulus GO:0071214 4 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.014
regulation of protein metabolic process GO:0051246 81 0.014
cellular protein complex assembly GO:0043623 178 0.014
positive regulation of mitotic sister chromatid separation GO:1901970 1 0.014
cell proliferation GO:0008283 116 0.014
response to temperature stimulus GO:0009266 66 0.014
cellular component morphogenesis GO:0032989 318 0.013
neuron projection guidance GO:0097485 82 0.013
single organism biosynthetic process GO:0044711 91 0.013
ribonucleoside triphosphate catabolic process GO:0009203 72 0.013
atp metabolic process GO:0046034 42 0.013
multi multicellular organism process GO:0044706 390 0.013
striated muscle myosin thick filament assembly GO:0071688 138 0.013
regulation of protein stability GO:0031647 3 0.013
response to abiotic stimulus GO:0009628 152 0.013
chromatin remodeling GO:0006338 2 0.013
modification dependent macromolecule catabolic process GO:0043632 32 0.013
ribonucleotide catabolic process GO:0009261 75 0.012
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.012
dna replication GO:0006260 15 0.012
myosin filament organization GO:0031033 138 0.012
intracellular signal transduction GO:0035556 96 0.012
metaphase anaphase transition of cell cycle GO:0044784 15 0.012
long term memory GO:0007616 2 0.012
negative regulation of cellular protein metabolic process GO:0032269 27 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.012
rho protein signal transduction GO:0007266 2 0.012
regulation of protein targeting GO:1903533 3 0.012
positive regulation of rna biosynthetic process GO:1902680 102 0.012
localization of cell GO:0051674 313 0.012
negative regulation of mitosis GO:0045839 4 0.012
chromatin modification GO:0016568 32 0.012
regulation of post embryonic development GO:0048580 260 0.012
mitotic cell cycle checkpoint GO:0007093 5 0.011
axon guidance GO:0007411 82 0.011
cell cycle switching mitotic to meiotic cell cycle GO:0051728 35 0.011
organonitrogen compound catabolic process GO:1901565 90 0.011
regulation of cellular amine metabolic process GO:0033238 0 0.011
regulation of phosphorylation GO:0042325 45 0.011
purine nucleoside monophosphate catabolic process GO:0009128 28 0.011
positive regulation of cellular component organization GO:0051130 34 0.011
regulation of mitosis GO:0007088 18 0.011
axon development GO:0061564 163 0.011
negative regulation of protein catabolic process GO:0042177 4 0.011
regulation of mitotic sister chromatid segregation GO:0033047 16 0.011
organophosphate catabolic process GO:0046434 81 0.011
carbohydrate derivative metabolic process GO:1901135 141 0.011
purine nucleoside metabolic process GO:0042278 92 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 5 0.011
negative regulation of cell cycle process GO:0010948 12 0.011
establishment of rna localization GO:0051236 3 0.011
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 4 0.011
phosphorylation GO:0016310 116 0.011
mitotic sister chromatid separation GO:0051306 13 0.011
tissue development GO:0009888 112 0.011
negative regulation of gene expression epigenetic GO:0045814 2 0.011
nitrogen compound transport GO:0071705 49 0.011
secretion GO:0046903 147 0.010
amine metabolic process GO:0009308 15 0.010
mitotic spindle checkpoint GO:0071174 4 0.010
protein localization to organelle GO:0033365 37 0.010
regulation of transcription regulatory region dna binding GO:2000677 3 0.010
response to heat GO:0009408 50 0.010

pri-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.021
nervous system disease DOID:863 0 0.010