Caenorhabditis elegans

17 known processes

brf-1 (CELE_F45E12.2)

Protein BRF-1

brf-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
genitalia development GO:0048806 741 0.413
sex differentiation GO:0007548 909 0.386
reproductive system development GO:0061458 850 0.377
development of primary sexual characteristics GO:0045137 840 0.368
establishment of localization GO:0051234 1171 0.331
embryo development GO:0009790 3052 0.330
regulation of transcription dna templated GO:0006355 164 0.317
reproductive structure development GO:0048608 850 0.315
gene expression GO:0010467 412 0.296
regulation of macromolecule metabolic process GO:0060255 421 0.294
regulation of gene expression GO:0010468 366 0.287
multicellular organismal aging GO:0010259 812 0.263
embryo development ending in birth or egg hatching GO:0009792 2992 0.245
regulation of nitrogen compound metabolic process GO:0051171 222 0.239
developmental process involved in reproduction GO:0003006 1165 0.235
regulation of metabolic process GO:0019222 478 0.226
chromosome organization GO:0051276 104 0.226
regulation of rna biosynthetic process GO:2001141 165 0.211
vesicle mediated transport GO:0016192 852 0.209
hermaphrodite genitalia development GO:0040035 734 0.209
regulation of rna metabolic process GO:0051252 173 0.207
locomotion GO:0040011 1634 0.201
positive regulation of cellular process GO:0048522 332 0.193
positive regulation of macromolecule metabolic process GO:0010604 149 0.174
chromatin modification GO:0016568 32 0.158
determination of adult lifespan GO:0008340 812 0.153
cell cycle GO:0007049 526 0.141
nucleobase containing compound metabolic process GO:0006139 406 0.136
regulation of nucleic acid templated transcription GO:1903506 165 0.136
positive regulation of nucleic acid templated transcription GO:1903508 102 0.131
cellular biosynthetic process GO:0044249 315 0.120
organic cyclic compound biosynthetic process GO:1901362 195 0.116
regulation of primary metabolic process GO:0080090 292 0.114
organ development GO:0048513 1102 0.113
single organism reproductive process GO:0044702 1196 0.112
post embryonic development GO:0009791 2152 0.107
nucleic acid templated transcription GO:0097659 169 0.107
aging GO:0007568 812 0.106
transcription dna templated GO:0006351 168 0.106
dna metabolic process GO:0006259 74 0.098
nucleic acid metabolic process GO:0090304 299 0.097
negative regulation of biological process GO:0048519 567 0.094
multicellular organism reproduction GO:0032504 819 0.089
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.088
cellular response to stress GO:0033554 162 0.087
histone modification GO:0016570 30 0.087
response to abiotic stimulus GO:0009628 152 0.087
chromatin organization GO:0006325 32 0.087
regulation of developmental process GO:0050793 684 0.086
regulation of macromolecule biosynthetic process GO:0010556 189 0.086
cell death GO:0008219 547 0.086
mitotic cell cycle process GO:1903047 194 0.083
negative regulation of metabolic process GO:0009892 240 0.082
biosynthetic process GO:0009058 323 0.080
transport GO:0006810 1093 0.079
negative regulation of macromolecule metabolic process GO:0010605 229 0.079
negative regulation of developmental process GO:0051093 227 0.078
chemotaxis GO:0006935 120 0.077
macromolecule localization GO:0033036 771 0.075
organelle organization GO:0006996 783 0.074
positive regulation of cellular biosynthetic process GO:0031328 109 0.071
regulation of cellular metabolic process GO:0031323 305 0.070
sexual reproduction GO:0019953 546 0.070
endocytosis GO:0006897 819 0.069
aromatic compound biosynthetic process GO:0019438 192 0.065
cellular macromolecule biosynthetic process GO:0034645 247 0.065
positive regulation of metabolic process GO:0009893 187 0.063
posttranscriptional regulation of gene expression GO:0010608 166 0.063
positive regulation of biosynthetic process GO:0009891 109 0.061
meiotic chromosome segregation GO:0045132 139 0.061
maintenance of location GO:0051235 580 0.060
protein metabolic process GO:0019538 422 0.059
rna metabolic process GO:0016070 228 0.056
intracellular signal transduction GO:0035556 96 0.056
single organism localization GO:1902578 518 0.054
response to external stimulus GO:0009605 289 0.054
negative regulation of gene expression GO:0010629 217 0.054
gene silencing GO:0016458 143 0.054
lipid storage GO:0019915 565 0.053
cellular component biogenesis GO:0044085 297 0.052
positive regulation of developmental process GO:0051094 408 0.052
regulation of cell proliferation GO:0042127 105 0.052
oxoacid metabolic process GO:0043436 47 0.052
programmed cell death GO:0012501 500 0.050
organic substance biosynthetic process GO:1901576 323 0.049
cellular nitrogen compound biosynthetic process GO:0044271 192 0.049
gene silencing by rna GO:0031047 143 0.049
regulation of gene expression epigenetic GO:0040029 163 0.048
multi organism reproductive process GO:0044703 867 0.048
regulation of biological quality GO:0065008 741 0.047
positive regulation of rna metabolic process GO:0051254 103 0.044
rna biosynthetic process GO:0032774 169 0.044
negative regulation of nematode larval development GO:0061064 208 0.044
regulation of biosynthetic process GO:0009889 189 0.044
regulation of multicellular organismal process GO:0051239 726 0.043
lipid localization GO:0010876 573 0.042
apoptotic process GO:0006915 478 0.042
regulation of post embryonic development GO:0048580 260 0.042
receptor mediated endocytosis GO:0006898 715 0.042
establishment of localization in cell GO:0051649 318 0.041
signal transduction GO:0007165 317 0.041
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.041
single organism signaling GO:0044700 401 0.040
covalent chromatin modification GO:0016569 30 0.039
meiotic nuclear division GO:0007126 300 0.039
posttranscriptional gene silencing GO:0016441 143 0.039
cellular response to organic substance GO:0071310 119 0.038
gonad development GO:0008406 840 0.037
single organism transport GO:0044765 447 0.035
negative regulation of cellular process GO:0048523 239 0.034
posttranscriptional gene silencing by rna GO:0035194 143 0.034
cell division GO:0051301 262 0.034
negative regulation of biosynthetic process GO:0009890 65 0.034
regulation of nematode larval development GO:0061062 260 0.033
cell morphogenesis GO:0000902 163 0.032
single organism organelle organization GO:1902589 501 0.031
protein phosphorylation GO:0006468 85 0.031
regulation of cell differentiation GO:0045595 81 0.031
signaling GO:0023052 401 0.031
multicellular organismal reproductive process GO:0048609 815 0.030
cell type specific apoptotic process GO:0097285 4 0.030
rna interference GO:0016246 137 0.030
regulation of cellular ketone metabolic process GO:0010565 3 0.030
positive regulation of gene expression GO:0010628 112 0.030
regulation of meiotic cell cycle GO:0051445 136 0.030
macromolecule biosynthetic process GO:0009059 250 0.029
cellular protein modification process GO:0006464 207 0.028
regulation of response to stimulus GO:0048583 243 0.028
body morphogenesis GO:0010171 620 0.028
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.028
regulation of multicellular organismal development GO:2000026 317 0.027
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.027
organelle fission GO:0048285 363 0.027
death GO:0016265 547 0.027
positive regulation of transcription dna templated GO:0045893 102 0.027
nucleobase containing compound biosynthetic process GO:0034654 184 0.026
meiotic cell cycle GO:0051321 335 0.026
cell cycle process GO:0022402 482 0.026
regulation of cellular biosynthetic process GO:0031326 189 0.025
neuron differentiation GO:0030182 217 0.025
carboxylic acid metabolic process GO:0019752 34 0.025
positive regulation of cell differentiation GO:0045597 8 0.025
cellular protein metabolic process GO:0044267 279 0.024
head development GO:0060322 1 0.024
negative regulation of cellular metabolic process GO:0031324 95 0.024
regulation of phosphate metabolic process GO:0019220 81 0.023
organonitrogen compound metabolic process GO:1901564 151 0.023
negative regulation of cellular biosynthetic process GO:0031327 65 0.023
single organism catabolic process GO:0044712 129 0.023
positive regulation of multicellular organismal process GO:0051240 417 0.022
cell development GO:0048468 696 0.022
cellular amino acid metabolic process GO:0006520 15 0.022
heterocycle biosynthetic process GO:0018130 187 0.021
cellular response to chemical stimulus GO:0070887 129 0.020
lipid metabolic process GO:0006629 77 0.020
cell projection organization GO:0030030 231 0.020
positive regulation of neurogenesis GO:0050769 4 0.020
response to chemical GO:0042221 356 0.019
response to bacterium GO:0009617 86 0.019
chromatin remodeling GO:0006338 2 0.019
nervous system development GO:0007399 253 0.019
negative regulation of post embryonic development GO:0048581 208 0.019
response to organic substance GO:0010033 131 0.019
autophagy GO:0006914 29 0.019
protein modification process GO:0036211 207 0.018
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.018
small molecule metabolic process GO:0044281 186 0.018
anatomical structure formation involved in morphogenesis GO:0048646 250 0.018
regulation of cell division GO:0051302 142 0.018
germ cell development GO:0007281 351 0.018
negative regulation of multicellular organismal process GO:0051241 236 0.018
regulation of intracellular signal transduction GO:1902531 77 0.017
regulation of locomotion GO:0040012 161 0.017
heterocycle catabolic process GO:0046700 119 0.017
intraspecies interaction between organisms GO:0051703 3 0.017
regulation of vulval development GO:0040028 248 0.017
positive regulation of multicellular organism growth GO:0040018 352 0.017
organophosphate metabolic process GO:0019637 125 0.016
catabolic process GO:0009056 318 0.016
regulation of cell cycle GO:0051726 194 0.016
generation of neurons GO:0048699 235 0.016
organic substance catabolic process GO:1901575 294 0.016
cellular ketone metabolic process GO:0042180 14 0.016
positive regulation of cellular metabolic process GO:0031325 178 0.016
phosphorylation GO:0016310 116 0.016
cellular response to extracellular stimulus GO:0031668 16 0.016
oviposition GO:0018991 364 0.015
regulation of cell communication GO:0010646 176 0.015
meiotic cell cycle process GO:1903046 170 0.015
regulation of cellular amine metabolic process GO:0033238 0 0.015
positive regulation of rna biosynthetic process GO:1902680 102 0.015
rna processing GO:0006396 34 0.015
regulation of cellular component size GO:0032535 40 0.015
cellular component morphogenesis GO:0032989 318 0.015
dna templated transcription elongation GO:0006354 1 0.015
regulation of cell cycle process GO:0010564 145 0.015
cellular response to dna damage stimulus GO:0006974 41 0.015
regulation of cellular component organization GO:0051128 248 0.014
regulation of organelle organization GO:0033043 164 0.014
transcription from rna polymerase ii promoter GO:0006366 149 0.014
neuron development GO:0048666 199 0.014
macromolecule modification GO:0043412 218 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
digestive tract morphogenesis GO:0048546 76 0.014
oogenesis GO:0048477 229 0.014
cell fate commitment GO:0045165 139 0.014
regulation of cellular protein metabolic process GO:0032268 75 0.014
peptidyl amino acid modification GO:0018193 58 0.014
organic acid metabolic process GO:0006082 47 0.014
response to temperature stimulus GO:0009266 66 0.014
carbohydrate derivative catabolic process GO:1901136 82 0.014
regulation of cellular carbohydrate metabolic process GO:0010675 2 0.014
cellular response to abiotic stimulus GO:0071214 4 0.013
negative regulation of rna biosynthetic process GO:1902679 53 0.013
macromolecular complex subunit organization GO:0043933 320 0.013
internal peptidyl lysine acetylation GO:0018393 3 0.013
multi organism behavior GO:0051705 389 0.013
regulation of catabolic process GO:0009894 57 0.013
defense response GO:0006952 296 0.013
regulation of programmed cell death GO:0043067 50 0.013
transcription elongation from rna polymerase ii promoter GO:0006368 1 0.013
gamete generation GO:0007276 461 0.013
cellular component assembly GO:0022607 293 0.013
developmental growth GO:0048589 412 0.013
taxis GO:0042330 128 0.013
peptidyl lysine acetylation GO:0018394 3 0.013
chromosome segregation GO:0007059 180 0.013
membrane organization GO:0061024 135 0.013
protein oligomerization GO:0051259 4 0.013
response to heat GO:0009408 50 0.013
positive regulation of molecular function GO:0044093 61 0.013
muscle structure development GO:0061061 191 0.013
cytoskeleton organization GO:0007010 339 0.012
regulation of neurogenesis GO:0050767 40 0.012
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.012
regulation of meiosis GO:0040020 94 0.012
multicellular organism growth GO:0035264 385 0.012
positive regulation of growth GO:0045927 369 0.012
muscle cell differentiation GO:0042692 171 0.012
cell growth GO:0016049 44 0.012
axon development GO:0061564 163 0.012
multi multicellular organism process GO:0044706 390 0.012
internal protein amino acid acetylation GO:0006475 3 0.012
membrane invagination GO:0010324 98 0.012
cell morphogenesis involved in differentiation GO:0000904 112 0.011
post embryonic organ development GO:0048569 336 0.011
regulation of mitotic cell cycle GO:0007346 76 0.011
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.011
aromatic compound catabolic process GO:0019439 116 0.011
positive regulation of phosphorus metabolic process GO:0010562 56 0.011
positive regulation of cell projection organization GO:0031346 4 0.011
phagocytosis engulfment GO:0006911 98 0.011
regulation of multicellular organism growth GO:0040014 373 0.011
response to other organism GO:0051707 101 0.011
establishment or maintenance of cell polarity GO:0007163 63 0.011
cellular nitrogen compound catabolic process GO:0044270 119 0.011
carbohydrate derivative metabolic process GO:1901135 141 0.011
regulation of muscle cell differentiation GO:0051147 1 0.010
nucleic acid phosphodiester bond hydrolysis GO:0090305 28 0.010
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.010
positive regulation of nuclease activity GO:0032075 1 0.010
amine metabolic process GO:0009308 15 0.010
neuron apoptotic process GO:0051402 4 0.010

brf-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
organ system cancer DOID:0050686 0 0.014
head and neck cancer DOID:11934 0 0.014