Caenorhabditis elegans

46 known processes

cul-4 (CELE_F45E12.3)

Protein CUL-4

cul-4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.739
embryo development ending in birth or egg hatching GO:0009792 2992 0.707
organ development GO:0048513 1102 0.577
post embryonic development GO:0009791 2152 0.569
sex differentiation GO:0007548 909 0.442
gonad development GO:0008406 840 0.346
single organism reproductive process GO:0044702 1196 0.345
single organism organelle organization GO:1902589 501 0.309
apoptotic process GO:0006915 478 0.291
macromolecular complex subunit organization GO:0043933 320 0.259
cellular component morphogenesis GO:0032989 318 0.253
cell part morphogenesis GO:0032990 152 0.231
establishment of localization GO:0051234 1171 0.224
development of primary sexual characteristics GO:0045137 840 0.197
cellular component assembly GO:0022607 293 0.194
cell development GO:0048468 696 0.192
multi organism reproductive process GO:0044703 867 0.190
genitalia development GO:0048806 741 0.183
hermaphrodite genitalia development GO:0040035 734 0.180
regulation of multicellular organismal development GO:2000026 317 0.170
developmental process involved in reproduction GO:0003006 1165 0.166
reproductive system development GO:0061458 850 0.161
locomotion GO:0040011 1634 0.160
programmed cell death GO:0012501 500 0.156
cellular component biogenesis GO:0044085 297 0.152
cell death GO:0008219 547 0.150
receptor mediated endocytosis GO:0006898 715 0.142
multicellular organism reproduction GO:0032504 819 0.140
multicellular organismal reproductive process GO:0048609 815 0.135
organelle organization GO:0006996 783 0.134
death GO:0016265 547 0.131
protein complex subunit organization GO:0071822 280 0.129
oviposition GO:0018991 364 0.129
regulation of developmental process GO:0050793 684 0.125
cell cycle GO:0007049 526 0.118
regulation of multicellular organismal process GO:0051239 726 0.117
reproductive structure development GO:0048608 850 0.107
cellular component assembly involved in morphogenesis GO:0010927 183 0.105
post embryonic organ development GO:0048569 336 0.100
negative regulation of nematode larval development GO:0061064 208 0.097
vesicle mediated transport GO:0016192 852 0.097
aging GO:0007568 812 0.096
actomyosin structure organization GO:0031032 154 0.094
endocytosis GO:0006897 819 0.093
regulation of cell cycle GO:0051726 194 0.092
vulval development GO:0040025 333 0.091
muscle structure development GO:0061061 191 0.090
positive regulation of rna biosynthetic process GO:1902680 102 0.085
anatomical structure formation involved in morphogenesis GO:0048646 250 0.082
multi multicellular organism process GO:0044706 390 0.081
cell morphogenesis GO:0000902 163 0.080
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.080
cellular localization GO:0051641 360 0.079
actin filament based process GO:0030029 191 0.077
regulation of cellular component organization GO:0051128 248 0.076
cytoskeleton organization GO:0007010 339 0.075
gene expression GO:0010467 412 0.074
macromolecule localization GO:0033036 771 0.074
protein metabolic process GO:0019538 422 0.072
regulation of vulval development GO:0040028 248 0.071
nucleic acid metabolic process GO:0090304 299 0.071
macromolecular complex assembly GO:0065003 193 0.069
molting cycle GO:0042303 281 0.069
regulation of cell communication GO:0010646 176 0.069
neuron differentiation GO:0030182 217 0.068
neuron development GO:0048666 199 0.067
cellular protein metabolic process GO:0044267 279 0.066
synaptic transmission GO:0007268 106 0.066
regulation of meiotic cell cycle GO:0051445 136 0.065
regulation of biological quality GO:0065008 741 0.065
protein complex biogenesis GO:0070271 186 0.065
sexual reproduction GO:0019953 546 0.064
generation of neurons GO:0048699 235 0.063
multi organism behavior GO:0051705 389 0.063
signaling GO:0023052 401 0.062
negative regulation of post embryonic development GO:0048581 208 0.061
regulation of macromolecule metabolic process GO:0060255 421 0.061
negative regulation of biological process GO:0048519 567 0.060
striated muscle cell differentiation GO:0051146 158 0.056
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.056
mitotic cell cycle process GO:1903047 194 0.056
cellular macromolecular complex assembly GO:0034622 184 0.056
neurogenesis GO:0022008 236 0.055
maintenance of location GO:0051235 580 0.054
muscle cell differentiation GO:0042692 171 0.054
lipid storage GO:0019915 565 0.053
determination of adult lifespan GO:0008340 812 0.053
cell division GO:0051301 262 0.053
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.053
regulation of metabolic process GO:0019222 478 0.052
rna metabolic process GO:0016070 228 0.052
chromatin modification GO:0016568 32 0.052
cell projection organization GO:0030030 231 0.051
actin cytoskeleton organization GO:0030036 184 0.051
regulation of macromolecule biosynthetic process GO:0010556 189 0.050
transcription dna templated GO:0006351 168 0.049
multicellular organismal aging GO:0010259 812 0.049
organelle assembly GO:0070925 214 0.049
regulation of response to stimulus GO:0048583 243 0.049
cell motility GO:0048870 313 0.049
lipid localization GO:0010876 573 0.048
regulation of nematode larval development GO:0061062 260 0.048
negative regulation of cellular process GO:0048523 239 0.048
striated muscle cell development GO:0055002 157 0.047
cellular protein complex assembly GO:0043623 178 0.047
regulation of transport GO:0051049 91 0.047
regulation of signaling GO:0023051 172 0.047
protein complex assembly GO:0006461 186 0.047
inductive cell migration GO:0040039 145 0.046
chromatin organization GO:0006325 32 0.046
multicellular organismal reproductive behavior GO:0033057 384 0.045
transport GO:0006810 1093 0.044
regulation of cell cycle process GO:0010564 145 0.043
cell proliferation GO:0008283 116 0.043
regulation of nuclear division GO:0051783 115 0.043
female gamete generation GO:0007292 254 0.042
single organism transport GO:0044765 447 0.042
localization of cell GO:0051674 313 0.041
chromosome organization GO:0051276 104 0.040
cellular macromolecule biosynthetic process GO:0034645 247 0.040
regulation of nitrogen compound metabolic process GO:0051171 222 0.040
organelle fission GO:0048285 363 0.040
positive regulation of rna metabolic process GO:0051254 103 0.039
protein catabolic process GO:0030163 162 0.039
regulation of post embryonic development GO:0048580 260 0.039
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.038
single organism signaling GO:0044700 401 0.038
oogenesis GO:0048477 229 0.038
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.037
response to abiotic stimulus GO:0009628 152 0.037
organic substance catabolic process GO:1901575 294 0.037
multicellular organism growth GO:0035264 385 0.036
positive regulation of multicellular organismal process GO:0051240 417 0.035
behavior GO:0007610 527 0.035
multi organism reproductive behavior GO:0044705 387 0.035
chromatin remodeling GO:0006338 2 0.035
signal transduction GO:0007165 317 0.034
negative regulation of developmental process GO:0051093 227 0.034
regulation of gene expression GO:0010468 366 0.034
dna metabolic process GO:0006259 74 0.034
negative regulation of macromolecule metabolic process GO:0010605 229 0.033
striated muscle myosin thick filament assembly GO:0071688 138 0.032
chromosome segregation GO:0007059 180 0.032
positive regulation of developmental process GO:0051094 408 0.031
posttranscriptional gene silencing GO:0016441 143 0.031
catabolic process GO:0009056 318 0.031
positive regulation of multicellular organism growth GO:0040018 352 0.030
regulation of cellular metabolic process GO:0031323 305 0.030
response to chemical GO:0042221 356 0.029
cellular biosynthetic process GO:0044249 315 0.029
regulation of biosynthetic process GO:0009889 189 0.028
macromolecule biosynthetic process GO:0009059 250 0.028
regulation of locomotion GO:0040012 161 0.028
histone modification GO:0016570 30 0.028
macromolecule catabolic process GO:0009057 202 0.028
myofibril assembly GO:0030239 154 0.027
cellular protein modification process GO:0006464 207 0.027
posttranscriptional gene silencing by rna GO:0035194 143 0.027
negative regulation of vulval development GO:0040027 206 0.026
negative regulation of gene expression GO:0010629 217 0.026
cellular component movement GO:0006928 388 0.026
germ cell development GO:0007281 351 0.026
response to wounding GO:0009611 4 0.026
positive regulation of gene expression GO:0010628 112 0.026
regulation of nucleic acid templated transcription GO:1903506 165 0.026
gamete generation GO:0007276 461 0.025
chromatin assembly or disassembly GO:0006333 1 0.025
positive regulation of transport GO:0051050 32 0.025
negative regulation of cellular biosynthetic process GO:0031327 65 0.025
reproductive behavior GO:0019098 387 0.024
macromolecule modification GO:0043412 218 0.024
regulation of organelle organization GO:0033043 164 0.024
positive regulation of nucleic acid templated transcription GO:1903508 102 0.024
phosphate containing compound metabolic process GO:0006796 232 0.024
rna localization GO:0006403 3 0.024
posttranscriptional regulation of gene expression GO:0010608 166 0.023
positive regulation of cellular process GO:0048522 332 0.023
meiotic cell cycle GO:0051321 335 0.023
positive regulation of response to stimulus GO:0048584 55 0.023
vesicle localization GO:0051648 24 0.023
establishment of localization in cell GO:0051649 318 0.023
negative regulation of multicellular organismal process GO:0051241 236 0.023
nervous system development GO:0007399 253 0.022
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.022
rna biosynthetic process GO:0032774 169 0.022
nucleobase containing compound metabolic process GO:0006139 406 0.021
regulation of growth GO:0040008 409 0.021
rna interference GO:0016246 137 0.021
positive regulation of cellular metabolic process GO:0031325 178 0.021
membrane organization GO:0061024 135 0.021
growth GO:0040007 562 0.021
head development GO:0060322 1 0.021
muscle cell development GO:0055001 158 0.020
regulation of multicellular organism growth GO:0040014 373 0.020
organic substance biosynthetic process GO:1901576 323 0.019
secretion GO:0046903 147 0.019
negative regulation of metabolic process GO:0009892 240 0.019
epithelial cell proliferation GO:0050673 1 0.019
single organism catabolic process GO:0044712 129 0.019
myosin filament organization GO:0031033 138 0.019
apoptotic cell clearance GO:0043277 111 0.019
regulation of rna metabolic process GO:0051252 173 0.019
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.019
response to external stimulus GO:0009605 289 0.018
cuticle development GO:0042335 100 0.018
regulation of localization GO:0032879 194 0.018
cell cycle process GO:0022402 482 0.018
regulation of mitotic cell cycle GO:0007346 76 0.018
regulation of multi organism process GO:0043900 69 0.018
myosin filament assembly GO:0031034 138 0.018
engulfment of apoptotic cell GO:0043652 94 0.017
phagocytosis engulfment GO:0006911 98 0.017
cellular macromolecule localization GO:0070727 75 0.017
positive regulation of growth GO:0045927 369 0.017
negative regulation of biosynthetic process GO:0009890 65 0.017
protein modification process GO:0036211 207 0.017
developmental growth GO:0048589 412 0.017
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.017
establishment of rna localization GO:0051236 3 0.017
nucleoside catabolic process GO:0009164 78 0.017
regulation of phosphorylation GO:0042325 45 0.017
dna duplex unwinding GO:0032508 3 0.016
neuron projection development GO:0031175 187 0.016
gene silencing by rna GO:0031047 143 0.016
gene silencing GO:0016458 143 0.016
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.016
regulation of cell division GO:0051302 142 0.016
regulation of rna biosynthetic process GO:2001141 165 0.016
pigmentation GO:0043473 2 0.016
cellular catabolic process GO:0044248 199 0.016
collagen and cuticulin based cuticle development GO:0040002 99 0.015
cell morphogenesis involved in differentiation GO:0000904 112 0.015
proteolysis GO:0006508 61 0.015
membrane invagination GO:0010324 98 0.015
transcription initiation from rna polymerase ii promoter GO:0006367 2 0.015
aromatic compound biosynthetic process GO:0019438 192 0.015
defense response GO:0006952 296 0.015
regulation of synaptic transmission GO:0050804 34 0.015
purine nucleotide catabolic process GO:0006195 75 0.014
neuron projection morphogenesis GO:0048812 114 0.014
cell migration GO:0016477 306 0.014
regulation of mitosis GO:0007088 18 0.014
dendrite development GO:0016358 42 0.014
organonitrogen compound metabolic process GO:1901564 151 0.014
internal peptidyl lysine acetylation GO:0018393 3 0.013
organic substance transport GO:0071702 113 0.013
spindle organization GO:0007051 92 0.013
nucleotide catabolic process GO:0009166 77 0.013
tube development GO:0035295 126 0.013
negative regulation of transcription dna templated GO:0045892 53 0.013
chromatin assembly GO:0031497 1 0.012
regulation of reproductive process GO:2000241 66 0.012
body morphogenesis GO:0010171 620 0.012
regulation of primary metabolic process GO:0080090 292 0.012
regulation of cell proliferation GO:0042127 105 0.012
amine metabolic process GO:0009308 15 0.012
positive regulation of developmental growth GO:0048639 354 0.012
establishment of vesicle localization GO:0051650 23 0.012
regulation of cellular amine metabolic process GO:0033238 0 0.012
organic cyclic compound biosynthetic process GO:1901362 195 0.012
regulation of gene expression epigenetic GO:0040029 163 0.012
positive regulation of protein transport GO:0051222 4 0.012
ribose phosphate metabolic process GO:0019693 99 0.012
mrna metabolic process GO:0016071 31 0.012
aromatic compound catabolic process GO:0019439 116 0.011
cellular protein localization GO:0034613 75 0.011
ribonucleoprotein complex assembly GO:0022618 4 0.011
organophosphate catabolic process GO:0046434 81 0.011
immune response GO:0006955 192 0.011
neurological system process GO:0050877 53 0.011
rna transport GO:0050658 3 0.011
carbohydrate derivative metabolic process GO:1901135 141 0.011
positive regulation of neurogenesis GO:0050769 4 0.011
regulation of meiosis GO:0040020 94 0.011
regulation of behavior GO:0050795 97 0.011
regulation of apoptotic signaling pathway GO:2001233 1 0.011
taxis GO:0042330 128 0.011
dna templated transcription elongation GO:0006354 1 0.010
regulation of developmental growth GO:0048638 389 0.010
single organism cellular localization GO:1902580 72 0.010
pole plasm assembly GO:0007315 2 0.010
pharyngeal pumping GO:0043050 58 0.010
regulation of nucleocytoplasmic transport GO:0046822 3 0.010
positive regulation of cellular biosynthetic process GO:0031328 109 0.010
pigment metabolic process GO:0042440 2 0.010
regulation of cellular ketone metabolic process GO:0010565 3 0.010
cytokinesis GO:0000910 80 0.010
axonal fasciculation GO:0007413 79 0.010

cul-4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.034
cancer DOID:162 0 0.024
disease of cellular proliferation DOID:14566 0 0.024
organ system cancer DOID:0050686 0 0.012