Caenorhabditis elegans

105 known processes

par-3 (CELE_F54E7.3)

Protein PAR-3

par-3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism signaling GO:0044700 401 0.715
Mouse Fly
single organism organelle organization GO:1902589 501 0.672
mitotic cell cycle process GO:1903047 194 0.652
localization of cell GO:0051674 313 0.585
Mouse Fly
regulation of primary metabolic process GO:0080090 292 0.450
Mouse
programmed cell death GO:0012501 500 0.416
microtubule based process GO:0007017 182 0.416
signal transduction GO:0007165 317 0.413
Fly
single organism cellular localization GO:1902580 72 0.388
organ development GO:0048513 1102 0.376
tissue development GO:0009888 112 0.343
Mouse Fly
phosphorus metabolic process GO:0006793 232 0.334
Mouse
locomotion GO:0040011 1634 0.318
Mouse Fly
cellular protein modification process GO:0006464 207 0.312
Mouse
reproductive structure development GO:0048608 850 0.308
embryo development GO:0009790 3052 0.307
cell development GO:0048468 696 0.290
Mouse Fly
cellular localization GO:0051641 360 0.290
protein complex subunit organization GO:0071822 280 0.281
phosphate containing compound metabolic process GO:0006796 232 0.276
Mouse
embryo development ending in birth or egg hatching GO:0009792 2992 0.272
macromolecular complex subunit organization GO:0043933 320 0.270
reproductive system development GO:0061458 850 0.269
cell migration GO:0016477 306 0.265
Mouse Fly
cell part morphogenesis GO:0032990 152 0.263
neuron differentiation GO:0030182 217 0.261
Fly
regulation of cellular component organization GO:0051128 248 0.247
Fly
cytoskeleton organization GO:0007010 339 0.235
regulation of axonogenesis GO:0050770 24 0.233
neuron projection development GO:0031175 187 0.229
developmental process involved in reproduction GO:0003006 1165 0.223
regulation of multicellular organismal process GO:0051239 726 0.221
regulation of cell communication GO:0010646 176 0.219
Fly
cell projection morphogenesis GO:0048858 148 0.205
regulation of developmental process GO:0050793 684 0.198
protein metabolic process GO:0019538 422 0.193
Mouse
apoptotic process GO:0006915 478 0.193
death GO:0016265 547 0.191
establishment of localization GO:0051234 1171 0.189
gonad development GO:0008406 840 0.186
signaling GO:0023052 401 0.184
Mouse Fly
protein localization GO:0008104 205 0.181
cell motility GO:0048870 313 0.181
Mouse Fly
cellular component movement GO:0006928 388 0.180
Mouse Fly
phosphorylation GO:0016310 116 0.176
Mouse
genitalia development GO:0048806 741 0.175
regulation of catalytic activity GO:0050790 78 0.172
macromolecule localization GO:0033036 771 0.168
neuron projection morphogenesis GO:0048812 114 0.167
organelle organization GO:0006996 783 0.158
regulation of neuron projection development GO:0010975 31 0.153
regulation of cell development GO:0060284 49 0.148
developmental growth GO:0048589 412 0.148
Fly
macromolecule modification GO:0043412 218 0.143
Mouse
post embryonic development GO:0009791 2152 0.134
neurogenesis GO:0022008 236 0.133
Mouse Fly
determination of adult lifespan GO:0008340 812 0.133
single organism localization GO:1902578 518 0.129
generation of neurons GO:0048699 235 0.129
Fly
sex differentiation GO:0007548 909 0.128
regulation of localization GO:0032879 194 0.127
regulation of multicellular organismal development GO:2000026 317 0.126
regulation of growth GO:0040008 409 0.123
Fly
regulation of cell morphogenesis GO:0022604 40 0.122
protein modification process GO:0036211 207 0.117
Mouse
regulation of cytoskeleton organization GO:0051493 41 0.115
cell cycle GO:0007049 526 0.113
growth GO:0040007 562 0.112
Fly
regulation of anatomical structure morphogenesis GO:0022603 51 0.110
Fly
regulation of macromolecule metabolic process GO:0060255 421 0.104
Mouse
regulation of biological quality GO:0065008 741 0.103
Mouse
regulation of developmental growth GO:0048638 389 0.101
Fly
multi organism reproductive process GO:0044703 867 0.099
cellular component morphogenesis GO:0032989 318 0.099
Mouse Fly
mapk cascade GO:0000165 31 0.095
regulation of phosphorus metabolic process GO:0051174 81 0.093
Mouse
regulation of transport GO:0051049 91 0.093
asymmetric stem cell division GO:0098722 8 0.090
Fly
protein complex assembly GO:0006461 186 0.090
negative regulation of biological process GO:0048519 567 0.090
cellular component assembly GO:0022607 293 0.090
Fly
axonogenesis GO:0007409 102 0.087
aging GO:0007568 812 0.085
cell morphogenesis involved in differentiation GO:0000904 112 0.085
Mouse Fly
rho protein signal transduction GO:0007266 2 0.084
cellular protein metabolic process GO:0044267 279 0.081
Mouse
endocytosis GO:0006897 819 0.080
organic substance transport GO:0071702 113 0.078
regulation of mapk cascade GO:0043408 23 0.078
nucleobase containing compound metabolic process GO:0006139 406 0.077
positive regulation of developmental process GO:0051094 408 0.077
Mouse
cell projection organization GO:0030030 231 0.076
Fly
regulation of nervous system development GO:0051960 41 0.076
Mouse
transport GO:0006810 1093 0.075
development of primary sexual characteristics GO:0045137 840 0.074
regulation of neurogenesis GO:0050767 40 0.074
regulation of signal transduction GO:0009966 135 0.074
Fly
cell morphogenesis GO:0000902 163 0.074
Mouse Fly
establishment of localization in cell GO:0051649 318 0.074
asymmetric protein localization GO:0008105 35 0.073
establishment of organelle localization GO:0051656 123 0.069
regulation of phosphate metabolic process GO:0019220 81 0.069
Mouse
protein complex biogenesis GO:0070271 186 0.068
gene expression GO:0010467 412 0.068
cell division GO:0051301 262 0.067
positive regulation of catalytic activity GO:0043085 59 0.067
body morphogenesis GO:0010171 620 0.066
negative regulation of multicellular organismal process GO:0051241 236 0.065
muscle structure development GO:0061061 191 0.064
cell surface receptor signaling pathway GO:0007166 149 0.064
Fly
cell death GO:0008219 547 0.062
female gamete generation GO:0007292 254 0.062
regulation of cell morphogenesis involved in differentiation GO:0010769 29 0.061
negative regulation of post embryonic development GO:0048581 208 0.060
cytokinesis GO:0000910 80 0.060
Fly
catabolic process GO:0009056 318 0.059
small molecule metabolic process GO:0044281 186 0.059
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.058
Fly
macromolecule catabolic process GO:0009057 202 0.058
oogenesis GO:0048477 229 0.058
Fly
regulation of extent of cell growth GO:0061387 20 0.058
regulation of molecular function GO:0065009 89 0.056
positive regulation of cell projection organization GO:0031346 4 0.056
regulation of neuron differentiation GO:0045664 40 0.055
regulation of transferase activity GO:0051338 31 0.054
lipid storage GO:0019915 565 0.054
multicellular organismal aging GO:0010259 812 0.054
positive regulation of multicellular organism growth GO:0040018 352 0.053
vesicle mediated transport GO:0016192 852 0.053
regulation of rna metabolic process GO:0051252 173 0.052
inductive cell migration GO:0040039 145 0.052
nervous system development GO:0007399 253 0.051
Mouse Fly
regulation of cell projection organization GO:0031344 38 0.051
Fly
response to temperature stimulus GO:0009266 66 0.051
cellular protein localization GO:0034613 75 0.050
positive regulation of growth GO:0045927 369 0.050
secretion GO:0046903 147 0.050
hermaphrodite genitalia development GO:0040035 734 0.050
vulval development GO:0040025 333 0.049
posttranscriptional regulation of gene expression GO:0010608 166 0.049
cellular macromolecule localization GO:0070727 75 0.049
regulation of metabolic process GO:0019222 478 0.047
Mouse
nucleic acid templated transcription GO:0097659 169 0.047
epithelium development GO:0060429 68 0.046
Mouse Fly
positive regulation of gtpase activity GO:0043547 28 0.045
response to heat GO:0009408 50 0.045
sexual reproduction GO:0019953 546 0.045
gene silencing GO:0016458 143 0.045
maintenance of location GO:0051235 580 0.045
organelle localization GO:0051640 127 0.044
behavior GO:0007610 527 0.044
macromolecular complex assembly GO:0065003 193 0.044
secretion by cell GO:0032940 138 0.044
nucleic acid metabolic process GO:0090304 299 0.044
neuron development GO:0048666 199 0.044
Fly
positive regulation of neurogenesis GO:0050769 4 0.044
receptor mediated endocytosis GO:0006898 715 0.044
lipid localization GO:0010876 573 0.043
organic cyclic compound catabolic process GO:1901361 119 0.043
positive regulation of phosphate metabolic process GO:0045937 56 0.043
cell fate commitment GO:0045165 139 0.042
Fly
epithelial cell proliferation GO:0050673 1 0.042
single organism transport GO:0044765 447 0.042
positive regulation of cellular process GO:0048522 332 0.041
Mouse
organic substance catabolic process GO:1901575 294 0.040
regulation of protein kinase activity GO:0045859 28 0.040
regulation of epithelial cell proliferation GO:0050678 1 0.039
establishment of cell polarity GO:0030010 46 0.039
oxoacid metabolic process GO:0043436 47 0.039
negative regulation of cellular process GO:0048523 239 0.039
Mouse Fly
regulation of gene expression epigenetic GO:0040029 163 0.038
posttranscriptional gene silencing GO:0016441 143 0.037
regulation of cell differentiation GO:0045595 81 0.037
protein phosphorylation GO:0006468 85 0.037
Mouse
regulation of ras gtpase activity GO:0032318 21 0.037
regulation of cell motility GO:2000145 57 0.037
regulation of cellular component movement GO:0051270 62 0.037
cell cycle process GO:0022402 482 0.036
cell proliferation GO:0008283 116 0.036
Fly
positive regulation of cell communication GO:0010647 69 0.036
phagocytosis GO:0006909 115 0.036
regulation of protein metabolic process GO:0051246 81 0.035
Mouse
regulation of response to stimulus GO:0048583 243 0.035
Fly
digestive tract development GO:0048565 122 0.035
multi multicellular organism process GO:0044706 390 0.035
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.035
Fly
regulation of biosynthetic process GO:0009889 189 0.035
regulation of locomotion GO:0040012 161 0.035
establishment of protein localization to membrane GO:0090150 3 0.035
organonitrogen compound metabolic process GO:1901564 151 0.035
regulation of cytoplasmic transport GO:1903649 3 0.035
intracellular signal transduction GO:0035556 96 0.034
positive regulation of signaling GO:0023056 66 0.034
anterior posterior pattern specification GO:0009952 27 0.034
meiotic cell cycle GO:0051321 335 0.034
negative regulation of macromolecule metabolic process GO:0010605 229 0.034
Mouse
positive regulation of transferase activity GO:0051347 21 0.033
positive regulation of ras gtpase activity GO:0032320 19 0.033
negative regulation of developmental process GO:0051093 227 0.033
positive regulation of metabolic process GO:0009893 187 0.033
regulation of cellular ketone metabolic process GO:0010565 3 0.032
cellular component biogenesis GO:0044085 297 0.031
Fly
response to fibroblast growth factor GO:0071774 5 0.031
regulation of cellular component size GO:0032535 40 0.030
heterocycle catabolic process GO:0046700 119 0.030
regulation of cell size GO:0008361 30 0.030
positive regulation of molecular function GO:0044093 61 0.030
multicellular organismal reproductive process GO:0048609 815 0.030
positive regulation of multicellular organismal process GO:0051240 417 0.030
Mouse
response to external stimulus GO:0009605 289 0.030
homeostatic process GO:0042592 51 0.029
regulation of multicellular organism growth GO:0040014 373 0.029
nucleobase containing compound catabolic process GO:0034655 114 0.029
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.029
embryonic pattern specification GO:0009880 21 0.029
Fly
regulation of catabolic process GO:0009894 57 0.029
anterior posterior axis specification GO:0009948 17 0.029
response to chemical GO:0042221 356 0.028
oocyte differentiation GO:0009994 45 0.028
Fly
positive regulation of phosphorylation GO:0042327 27 0.028
cellular macromolecular complex assembly GO:0034622 184 0.028
stem cell division GO:0017145 18 0.028
Fly
germ cell development GO:0007281 351 0.027
Fly
positive regulation of jnk cascade GO:0046330 3 0.027
regulation of intracellular signal transduction GO:1902531 77 0.027
cuticle development GO:0042335 100 0.027
dauer larval development GO:0040024 92 0.027
ras protein signal transduction GO:0007265 31 0.026
positive regulation of organ growth GO:0046622 4 0.026
regulation of cell cycle GO:0051726 194 0.025
regulation of cellular amine metabolic process GO:0033238 0 0.025
positive regulation of protein metabolic process GO:0051247 45 0.025
digestive system development GO:0055123 122 0.025
regulation of gene expression GO:0010468 366 0.025
actin cytoskeleton organization GO:0030036 184 0.024
regulation of embryonic development GO:0045995 16 0.024
cellular ketone metabolic process GO:0042180 14 0.024
regulation of cellular metabolic process GO:0031323 305 0.024
Mouse
organic acid metabolic process GO:0006082 47 0.024
regulation of kinase activity GO:0043549 29 0.024
negative regulation of gene expression GO:0010629 217 0.024
posttranscriptional gene silencing by rna GO:0035194 143 0.023
response to oxygen containing compound GO:1901700 44 0.023
response to abiotic stimulus GO:0009628 152 0.023
chromosome segregation GO:0007059 180 0.023
multi organism behavior GO:0051705 389 0.023
multi organism reproductive behavior GO:0044705 387 0.023
positive regulation of cellular metabolic process GO:0031325 178 0.023
reproductive behavior GO:0019098 387 0.023
protein transport GO:0015031 45 0.023
peptidyl serine phosphorylation GO:0018105 20 0.022
mitotic nuclear division GO:0007067 89 0.022
post embryonic organ development GO:0048569 336 0.022
signal transduction by phosphorylation GO:0023014 31 0.022
gamete generation GO:0007276 461 0.022
cellular protein complex assembly GO:0043623 178 0.022
multicellular organism reproduction GO:0032504 819 0.022
organelle assembly GO:0070925 214 0.022
positive regulation of stress activated mapk cascade GO:0032874 3 0.022
cellular catabolic process GO:0044248 199 0.022
axon development GO:0061564 163 0.022
regulation of phosphorylation GO:0042325 45 0.022
Mouse
biosynthetic process GO:0009058 323 0.021
oviposition GO:0018991 364 0.021
establishment of spindle localization GO:0051293 51 0.021
single organism intracellular transport GO:1902582 70 0.021
establishment or maintenance of cell polarity GO:0007163 63 0.021
regulation of nucleocytoplasmic transport GO:0046822 3 0.021
regulation of signaling GO:0023051 172 0.021
Fly
regulation of ras protein signal transduction GO:0046578 41 0.021
positive regulation of developmental growth GO:0048639 354 0.021
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.021
membrane invagination GO:0010324 98 0.021
peptidyl amino acid modification GO:0018193 58 0.020
Mouse
muscle cell differentiation GO:0042692 171 0.020
spindle organization GO:0007051 92 0.020
cell type specific apoptotic process GO:0097285 4 0.020
response to organic substance GO:0010033 131 0.020
cellular nitrogen compound biosynthetic process GO:0044271 192 0.019
regulation of cell proliferation GO:0042127 105 0.019
head development GO:0060322 1 0.019
regulation of organelle organization GO:0033043 164 0.019
regulation of protein modification process GO:0031399 46 0.019
Mouse
regulation of cellular protein metabolic process GO:0032268 75 0.019
Mouse
purine containing compound metabolic process GO:0072521 95 0.019
immune response GO:0006955 192 0.019
establishment of mitotic spindle orientation GO:0000132 28 0.019
gene silencing by rna GO:0031047 143 0.019
response to wounding GO:0009611 4 0.019
Mouse
cell substrate adhesion GO:0031589 1 0.018
regulation of reproductive process GO:2000241 66 0.018
chromosome organization GO:0051276 104 0.018
establishment of protein localization GO:0045184 50 0.018
phagocytosis engulfment GO:0006911 98 0.018
skeletal muscle organ development GO:0060538 3 0.018
somatic stem cell division GO:0048103 9 0.018
Fly
regulation of nematode larval development GO:0061062 260 0.017
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 34 0.017
cellular nitrogen compound catabolic process GO:0044270 119 0.017
protein oligomerization GO:0051259 4 0.017
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.017
meiotic nuclear division GO:0007126 300 0.017
organic cyclic compound biosynthetic process GO:1901362 195 0.017
intracellular transport GO:0046907 77 0.017
positive regulation of signal transduction GO:0009967 40 0.017
carboxylic acid metabolic process GO:0019752 34 0.016
regulation of small gtpase mediated signal transduction GO:0051056 41 0.016
cellular amine metabolic process GO:0044106 15 0.016
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
innate immune response GO:0045087 190 0.015
collagen and cuticulin based cuticle development GO:0040002 99 0.015
cellular component assembly involved in morphogenesis GO:0010927 183 0.015
positive regulation of catabolic process GO:0009896 38 0.015
multicellular organismal reproductive behavior GO:0033057 384 0.015
actomyosin structure organization GO:0031032 154 0.015
regulation of map kinase activity GO:0043405 13 0.015
internal peptidyl lysine acetylation GO:0018393 3 0.015
regulation of cellular biosynthetic process GO:0031326 189 0.015
regulation of rna biosynthetic process GO:2001141 165 0.014
regulation of cell division GO:0051302 142 0.014
asymmetric cell division GO:0008356 36 0.014
muscle tissue development GO:0060537 1 0.014
multicellular organism growth GO:0035264 385 0.014
carbohydrate derivative metabolic process GO:1901135 141 0.014
positive regulation of macromolecule metabolic process GO:0010604 149 0.014
negative regulation of protein metabolic process GO:0051248 27 0.014
Mouse
negative regulation of metabolic process GO:0009892 240 0.014
Mouse
negative regulation of response to external stimulus GO:0032102 3 0.013
single organism carbohydrate metabolic process GO:0044723 29 0.013
feeding behavior GO:0007631 70 0.013
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.013
pattern specification process GO:0007389 59 0.013
apoptotic cell clearance GO:0043277 111 0.013
organelle fission GO:0048285 363 0.013
aromatic compound catabolic process GO:0019439 116 0.013
myosin filament organization GO:0031033 138 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.012
negative regulation of signaling GO:0023057 61 0.012
rna interference GO:0016246 137 0.012
chondroitin sulfate proteoglycan biosynthetic process GO:0050650 3 0.012
negative regulation of response to stimulus GO:0048585 73 0.012
skin development GO:0043588 24 0.012
enzyme linked receptor protein signaling pathway GO:0007167 50 0.012
positive regulation of intracellular transport GO:0032388 2 0.012
cellular macromolecule catabolic process GO:0044265 73 0.012
peptidyl serine modification GO:0018209 20 0.012
response to external biotic stimulus GO:0043207 101 0.012
positive regulation of programmed cell death GO:0043068 27 0.012
organophosphate catabolic process GO:0046434 81 0.012
organic substance biosynthetic process GO:1901576 323 0.012
cellular amino acid metabolic process GO:0006520 15 0.012
rna metabolic process GO:0016070 228 0.012
regulation of endocytosis GO:0030100 25 0.012
spindle localization GO:0051653 51 0.012
endosomal transport GO:0016197 26 0.011
guanosine containing compound metabolic process GO:1901068 49 0.011
peptidyl tyrosine modification GO:0018212 3 0.011
regulation of cell cell adhesion GO:0022407 1 0.011
Fly
oocyte axis specification GO:0007309 2 0.011
Fly
positive regulation of protein modification process GO:0031401 29 0.011
cellular macromolecule biosynthetic process GO:0034645 247 0.011
single organism catabolic process GO:0044712 129 0.011
macromolecule biosynthetic process GO:0009059 250 0.011
cell junction organization GO:0034330 18 0.011
Fly
striated muscle cell differentiation GO:0051146 158 0.011
actin filament based process GO:0030029 191 0.011
Mouse
amine metabolic process GO:0009308 15 0.010
regulation of cell cycle process GO:0010564 145 0.010
regulation of behavior GO:0050795 97 0.010
single organism reproductive process GO:0044702 1196 0.010
regulation of organ morphogenesis GO:2000027 4 0.010
Fly
synaptic growth at neuromuscular junction GO:0051124 1 0.010
regulation of protein localization GO:0032880 50 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.010
positive regulation of response to stimulus GO:0048584 55 0.010
negative regulation of signal transduction GO:0009968 60 0.010

par-3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.028
large intestine cancer DOID:5672 0 0.011
gastrointestinal system cancer DOID:3119 0 0.011
intestinal cancer DOID:10155 0 0.011
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.011