Caenorhabditis elegans

10 known processes

max-1 (CELE_C34B4.1)

Protein MAX-1

max-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.510
embryo development ending in birth or egg hatching GO:0009792 2992 0.415
nucleic acid metabolic process GO:0090304 299 0.264
sexual reproduction GO:0019953 546 0.255
multicellular organism reproduction GO:0032504 819 0.254
generation of neurons GO:0048699 235 0.219
cell development GO:0048468 696 0.213
protein complex subunit organization GO:0071822 280 0.207
Mouse
multicellular organismal reproductive process GO:0048609 815 0.200
cell cycle process GO:0022402 482 0.196
rna biosynthetic process GO:0032774 169 0.189
signaling GO:0023052 401 0.187
single organism signaling GO:0044700 401 0.176
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.176
regulation of biosynthetic process GO:0009889 189 0.175
cellular component morphogenesis GO:0032989 318 0.174
rna metabolic process GO:0016070 228 0.160
cellular component movement GO:0006928 388 0.158
nucleic acid templated transcription GO:0097659 169 0.156
cell morphogenesis involved in differentiation GO:0000904 112 0.155
regulation of cellular biosynthetic process GO:0031326 189 0.155
body morphogenesis GO:0010171 620 0.153
programmed cell death GO:0012501 500 0.152
regulation of metabolic process GO:0019222 478 0.151
locomotion GO:0040011 1634 0.146
vesicle mediated transport GO:0016192 852 0.145
regulation of nitrogen compound metabolic process GO:0051171 222 0.143
gamete generation GO:0007276 461 0.141
cell projection organization GO:0030030 231 0.138
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.138
organic cyclic compound biosynthetic process GO:1901362 195 0.137
heterocycle biosynthetic process GO:0018130 187 0.137
cellular macromolecule biosynthetic process GO:0034645 247 0.137
chemotaxis GO:0006935 120 0.130
single organism organelle organization GO:1902589 501 0.129
Mouse
cellular biosynthetic process GO:0044249 315 0.129
transcription from rna polymerase ii promoter GO:0006366 149 0.129
regulation of rna metabolic process GO:0051252 173 0.128
multicellular organismal aging GO:0010259 812 0.127
organonitrogen compound metabolic process GO:1901564 151 0.127
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.127
female gamete generation GO:0007292 254 0.126
cell death GO:0008219 547 0.125
organic substance biosynthetic process GO:1901576 323 0.124
single organism reproductive process GO:0044702 1196 0.120
macromolecule biosynthetic process GO:0009059 250 0.117
signal transduction GO:0007165 317 0.117
regulation of multicellular organismal development GO:2000026 317 0.116
cell migration GO:0016477 306 0.114
germ cell development GO:0007281 351 0.114
apoptotic process GO:0006915 478 0.113
establishment of localization GO:0051234 1171 0.112
regulation of rna biosynthetic process GO:2001141 165 0.112
death GO:0016265 547 0.112
regulation of transcription dna templated GO:0006355 164 0.111
regulation of primary metabolic process GO:0080090 292 0.109
head development GO:0060322 1 0.109
actin filament based process GO:0030029 191 0.104
Mouse
positive regulation of cellular process GO:0048522 332 0.103
multi organism reproductive process GO:0044703 867 0.102
neuron projection development GO:0031175 187 0.101
small molecule metabolic process GO:0044281 186 0.101
developmental process involved in reproduction GO:0003006 1165 0.100
cell projection morphogenesis GO:0048858 148 0.100
regulation of biological quality GO:0065008 741 0.093
Mouse
regulation of multicellular organismal process GO:0051239 726 0.092
oogenesis GO:0048477 229 0.092
small gtpase mediated signal transduction GO:0007264 32 0.090
positive regulation of rna biosynthetic process GO:1902680 102 0.090
mesodermal cell migration GO:0008078 9 0.089
nucleobase containing compound metabolic process GO:0006139 406 0.088
cell cycle GO:0007049 526 0.088
cell part morphogenesis GO:0032990 152 0.087
cellular component assembly GO:0022607 293 0.086
establishment of organelle localization GO:0051656 123 0.086
gene expression GO:0010467 412 0.085
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.084
cell motility GO:0048870 313 0.083
transport GO:0006810 1093 0.082
response to external stimulus GO:0009605 289 0.082
positive regulation of cellular metabolic process GO:0031325 178 0.082
regulation of cellular metabolic process GO:0031323 305 0.080
nucleobase containing compound biosynthetic process GO:0034654 184 0.079
axon development GO:0061564 163 0.078
cytoskeleton organization GO:0007010 339 0.075
Mouse
sex differentiation GO:0007548 909 0.075
regulation of signaling GO:0023051 172 0.074
hermaphrodite genitalia development GO:0040035 734 0.073
reproductive structure development GO:0048608 850 0.072
localization of cell GO:0051674 313 0.072
aromatic compound biosynthetic process GO:0019438 192 0.072
regulation of developmental process GO:0050793 684 0.072
organelle localization GO:0051640 127 0.070
neuron development GO:0048666 199 0.070
multi organism behavior GO:0051705 389 0.069
macromolecule localization GO:0033036 771 0.068
determination of adult lifespan GO:0008340 812 0.067
regulation of cell differentiation GO:0045595 81 0.067
positive regulation of metabolic process GO:0009893 187 0.065
cellular nitrogen compound biosynthetic process GO:0044271 192 0.065
striated muscle cell development GO:0055002 157 0.064
synaptic vesicle localization GO:0097479 22 0.064
growth GO:0040007 562 0.064
receptor mediated endocytosis GO:0006898 715 0.064
ribonucleotide catabolic process GO:0009261 75 0.062
regulation of gene expression GO:0010468 366 0.061
nervous system development GO:0007399 253 0.061
positive regulation of rna metabolic process GO:0051254 103 0.060
regulation of macromolecule biosynthetic process GO:0010556 189 0.060
regulation of response to stimulus GO:0048583 243 0.059
maintenance of location GO:0051235 580 0.059
regulation of developmental growth GO:0048638 389 0.057
cellular catabolic process GO:0044248 199 0.057
behavior GO:0007610 527 0.056
sensory organ morphogenesis GO:0090596 2 0.056
lipid storage GO:0019915 565 0.055
tissue development GO:0009888 112 0.055
Zebrafish
oviposition GO:0018991 364 0.054
biosynthetic process GO:0009058 323 0.054
neurogenesis GO:0022008 236 0.053
endocytosis GO:0006897 819 0.053
negative regulation of biological process GO:0048519 567 0.053
Mouse
multicellular organismal reproductive behavior GO:0033057 384 0.053
organic substance catabolic process GO:1901575 294 0.051
macromolecular complex subunit organization GO:0043933 320 0.051
Mouse
single organism localization GO:1902578 518 0.050
cellular component biogenesis GO:0044085 297 0.049
cellular protein complex assembly GO:0043623 178 0.048
organelle organization GO:0006996 783 0.047
Mouse
anatomical structure formation involved in morphogenesis GO:0048646 250 0.046
Zebrafish
protein complex assembly GO:0006461 186 0.046
negative regulation of cellular process GO:0048523 239 0.046
Mouse
taxis GO:0042330 128 0.045
post embryonic development GO:0009791 2152 0.044
nucleoside phosphate metabolic process GO:0006753 108 0.044
neuron projection morphogenesis GO:0048812 114 0.044
regulation of macromolecule metabolic process GO:0060255 421 0.044
lipid localization GO:0010876 573 0.043
positive regulation of growth GO:0045927 369 0.042
vesicle localization GO:0051648 24 0.042
myosin filament assembly GO:0031034 138 0.042
response to chemical GO:0042221 356 0.041
oocyte development GO:0048599 44 0.041
development of primary sexual characteristics GO:0045137 840 0.040
phosphorus metabolic process GO:0006793 232 0.040
myofibril assembly GO:0030239 154 0.040
regulation of cell communication GO:0010646 176 0.040
positive regulation of macromolecule metabolic process GO:0010604 149 0.040
negative regulation of bmp signaling pathway GO:0030514 1 0.040
nucleotide metabolic process GO:0009117 108 0.040
actin cytoskeleton organization GO:0030036 184 0.039
Mouse
regulation of localization GO:0032879 194 0.039
dorsal ventral axon guidance GO:0033563 19 0.039
aging GO:0007568 812 0.038
striated muscle myosin thick filament assembly GO:0071688 138 0.038
cell morphogenesis GO:0000902 163 0.038
regulation of nucleic acid templated transcription GO:1903506 165 0.038
organelle assembly GO:0070925 214 0.038
positive regulation of multicellular organismal process GO:0051240 417 0.038
organ development GO:0048513 1102 0.037
muscle cell development GO:0055001 158 0.037
neuromuscular junction development GO:0007528 2 0.036
regulation of anatomical structure morphogenesis GO:0022603 51 0.036
multi organism reproductive behavior GO:0044705 387 0.036
neuron differentiation GO:0030182 217 0.035
positive regulation of cellular biosynthetic process GO:0031328 109 0.035
post embryonic organ development GO:0048569 336 0.035
cellular component assembly involved in morphogenesis GO:0010927 183 0.035
regulation of growth GO:0040008 409 0.034
cellular macromolecular complex assembly GO:0034622 184 0.034
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.034
directional locomotion GO:0033058 14 0.034
gonad development GO:0008406 840 0.034
transcription dna templated GO:0006351 168 0.034
excretion GO:0007588 49 0.033
reproductive behavior GO:0019098 387 0.033
eating behavior GO:0042755 59 0.033
cellular response to organic substance GO:0071310 119 0.033
developmental growth GO:0048589 412 0.033
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.033
purine containing compound metabolic process GO:0072521 95 0.033
actomyosin structure organization GO:0031032 154 0.032
cell division GO:0051301 262 0.032
organic cyclic compound catabolic process GO:1901361 119 0.032
pattern specification process GO:0007389 59 0.032
Zebrafish
tube development GO:0035295 126 0.031
Zebrafish
regulation of cellular component organization GO:0051128 248 0.031
Mouse
system process GO:0003008 136 0.031
muscle structure development GO:0061061 191 0.031
protein metabolic process GO:0019538 422 0.031
embryonic morphogenesis GO:0048598 152 0.031
innate immune response GO:0045087 190 0.030
cellular response to stress GO:0033554 162 0.030
positive regulation of developmental growth GO:0048639 354 0.030
reproductive system development GO:0061458 850 0.030
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.030
protein complex biogenesis GO:0070271 186 0.030
male sex differentiation GO:0046661 86 0.030
nucleobase containing small molecule metabolic process GO:0055086 115 0.030
catabolic process GO:0009056 318 0.029
enzyme linked receptor protein signaling pathway GO:0007167 50 0.029
digestive tract development GO:0048565 122 0.029
muscle cell differentiation GO:0042692 171 0.029
multi multicellular organism process GO:0044706 390 0.029
immune response GO:0006955 192 0.029
canonical wnt signaling pathway GO:0060070 3 0.029
microtubule based process GO:0007017 182 0.029
cellular localization GO:0051641 360 0.028
single organism transport GO:0044765 447 0.028
negative regulation of biosynthetic process GO:0009890 65 0.028
negative regulation of gene expression GO:0010629 217 0.028
regulation of cell morphogenesis GO:0022604 40 0.028
macromolecular complex assembly GO:0065003 193 0.028
myosin filament organization GO:0031033 138 0.027
cell cell signaling GO:0007267 118 0.027
feeding behavior GO:0007631 70 0.027
striated muscle cell differentiation GO:0051146 158 0.027
regulation of phosphate metabolic process GO:0019220 81 0.027
regulation of multicellular organism growth GO:0040014 373 0.026
motor neuron axon guidance GO:0008045 13 0.026
regulation of bmp signaling pathway GO:0030510 3 0.026
purine nucleoside triphosphate catabolic process GO:0009146 72 0.026
macromolecule catabolic process GO:0009057 202 0.026
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.026
response to heat GO:0009408 50 0.026
protein localization GO:0008104 205 0.026
ribose phosphate metabolic process GO:0019693 99 0.026
regulation of small gtpase mediated signal transduction GO:0051056 41 0.026
establishment of vesicle localization GO:0051650 23 0.025
epithelial tube morphogenesis GO:0060562 1 0.025
Zebrafish
nucleotide catabolic process GO:0009166 77 0.025
ribonucleotide metabolic process GO:0009259 99 0.025
organonitrogen compound catabolic process GO:1901565 90 0.025
organophosphate metabolic process GO:0019637 125 0.025
positive regulation of developmental process GO:0051094 408 0.025
oocyte differentiation GO:0009994 45 0.024
phosphorylation GO:0016310 116 0.024
regulation of organelle organization GO:0033043 164 0.024
Mouse
negative regulation of developmental process GO:0051093 227 0.024
genitalia development GO:0048806 741 0.023
regulation of ras protein signal transduction GO:0046578 41 0.023
negative regulation of multicellular organismal process GO:0051241 236 0.023
organophosphate catabolic process GO:0046434 81 0.023
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.022
synaptic transmission GO:0007268 106 0.022
regulation of apoptotic signaling pathway GO:2001233 1 0.022
response to endoplasmic reticulum stress GO:0034976 71 0.022
purine ribonucleoside metabolic process GO:0046128 92 0.022
response to abiotic stimulus GO:0009628 152 0.022
nucleobase containing compound catabolic process GO:0034655 114 0.022
p38mapk cascade GO:0038066 2 0.022
ribonucleoside triphosphate metabolic process GO:0009199 87 0.022
purine ribonucleotide catabolic process GO:0009154 75 0.022
cell maturation GO:0048469 26 0.022
ribonucleoside triphosphate catabolic process GO:0009203 72 0.021
regulation of actin filament based process GO:0032970 22 0.021
Mouse
muscle tissue development GO:0060537 1 0.021
neuron recognition GO:0008038 83 0.021
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.021
regulation of cell cycle GO:0051726 194 0.021
carboxylic acid metabolic process GO:0019752 34 0.021
defense response GO:0006952 296 0.021
response to bacterium GO:0009617 86 0.021
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.021
nematode male tail tip morphogenesis GO:0045138 77 0.020
organic acid metabolic process GO:0006082 47 0.020
axonal fasciculation GO:0007413 79 0.020
axonogenesis GO:0007409 102 0.020
nucleoside catabolic process GO:0009164 78 0.020
cell type specific apoptotic process GO:0097285 4 0.020
intracellular signal transduction GO:0035556 96 0.019
positive regulation of multicellular organism growth GO:0040018 352 0.019
positive regulation of catalytic activity GO:0043085 59 0.019
regulation of nucleotide metabolic process GO:0006140 37 0.019
regulation of multi organism process GO:0043900 69 0.019
negative regulation of macromolecule metabolic process GO:0010605 229 0.019
pharyngeal pumping GO:0043050 58 0.019
synaptic vesicle transport GO:0048489 21 0.018
negative regulation of metabolic process GO:0009892 240 0.018
oxoacid metabolic process GO:0043436 47 0.018
mating GO:0007618 34 0.018
bmp signaling pathway GO:0030509 3 0.018
signal transduction by phosphorylation GO:0023014 31 0.018
membrane invagination GO:0010324 98 0.018
negative regulation of response to stimulus GO:0048585 73 0.018
regulation of cell death GO:0010941 65 0.018
positive regulation of neuron projection development GO:0010976 4 0.018
cellular protein localization GO:0034613 75 0.018
response to biotic stimulus GO:0009607 101 0.018
positive regulation of nucleic acid templated transcription GO:1903508 102 0.018
axon guidance GO:0007411 82 0.017
cell recognition GO:0008037 85 0.017
ras protein signal transduction GO:0007265 31 0.017
positive regulation of transcription from rna polymerase ii promoter in response to osmotic stress GO:0061393 1 0.017
negative regulation of signaling GO:0023057 61 0.017
ribonucleoside catabolic process GO:0042454 77 0.017
positive regulation of phosphorus metabolic process GO:0010562 56 0.017
purine containing compound catabolic process GO:0072523 75 0.017
mapk cascade GO:0000165 31 0.017
positive regulation of cell projection organization GO:0031346 4 0.016
regulation of cell development GO:0060284 49 0.016
positive regulation of intracellular transport GO:0032388 2 0.016
cell proliferation GO:0008283 116 0.016
protein catabolic process GO:0030163 162 0.016
carbohydrate derivative metabolic process GO:1901135 141 0.016
regulation of nucleoside metabolic process GO:0009118 37 0.016
nucleoside triphosphate catabolic process GO:0009143 72 0.016
digestive system development GO:0055123 122 0.016
negative regulation of axon extension GO:0030517 2 0.016
positive regulation of synaptic transmission GO:0050806 24 0.016
purine nucleoside metabolic process GO:0042278 92 0.016
purine nucleoside triphosphate metabolic process GO:0009144 87 0.016
skeletal muscle organ development GO:0060538 3 0.016
cellular protein metabolic process GO:0044267 279 0.016
regulation of protein localization GO:0032880 50 0.016
positive regulation of locomotion GO:0040017 42 0.016
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 16 0.016
regulation of locomotion GO:0040012 161 0.015
response to organic substance GO:0010033 131 0.015
cation transport GO:0006812 78 0.015
purine nucleoside catabolic process GO:0006152 75 0.015
phosphate containing compound metabolic process GO:0006796 232 0.015
negative regulation of neurogenesis GO:0050768 4 0.015
muscle fiber development GO:0048747 2 0.015
aromatic compound catabolic process GO:0019439 116 0.015
developmental maturation GO:0021700 26 0.015
axon extension GO:0048675 37 0.015
positive regulation of molecular function GO:0044093 61 0.015
nucleoside triphosphate metabolic process GO:0009141 87 0.015
epithelium development GO:0060429 68 0.015
Zebrafish
response to temperature stimulus GO:0009266 66 0.015
nucleoside metabolic process GO:0009116 99 0.015
rna localization GO:0006403 3 0.015
establishment of localization in cell GO:0051649 318 0.015
regulation of nucleotide catabolic process GO:0030811 35 0.015
cell surface receptor signaling pathway GO:0007166 149 0.014
regulation of cell proliferation GO:0042127 105 0.014
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.014
cellular macromolecule localization GO:0070727 75 0.014
positive regulation of transcription dna templated GO:0045893 102 0.014
defense response to gram negative bacterium GO:0050829 64 0.014
regulation of molecular function GO:0065009 89 0.014
tube morphogenesis GO:0035239 79 0.014
Zebrafish
cellular nitrogen compound catabolic process GO:0044270 119 0.014
cellular response to abiotic stimulus GO:0071214 4 0.014
heterocycle catabolic process GO:0046700 119 0.014
purine nucleotide catabolic process GO:0006195 75 0.014
positive regulation of nucleoside metabolic process GO:0045979 28 0.014
purine nucleotide metabolic process GO:0006163 95 0.014
regulation of purine nucleotide metabolic process GO:1900542 37 0.014
negative regulation of signal transduction GO:0009968 60 0.013
single organism behavior GO:0044708 83 0.013
regulation of pharyngeal pumping GO:0043051 36 0.013
lamellipodium organization GO:0097581 2 0.013
regulation of vulval development GO:0040028 248 0.013
positive regulation of catabolic process GO:0009896 38 0.013
glycosyl compound catabolic process GO:1901658 79 0.013
regulation of canonical wnt signaling pathway GO:0060828 1 0.013
regulation of signal transduction GO:0009966 135 0.013
regulation of behavior GO:0050795 97 0.013
cellular amine metabolic process GO:0044106 15 0.013
regulation of gtp catabolic process GO:0033124 32 0.013
sensory perception of taste GO:0050909 4 0.013
positive regulation of biosynthetic process GO:0009891 109 0.013
negative regulation of cellular biosynthetic process GO:0031327 65 0.013
regulation of nucleocytoplasmic transport GO:0046822 3 0.013
negative regulation of rna biosynthetic process GO:1902679 53 0.012
ribonucleoside metabolic process GO:0009119 98 0.012
purine ribonucleoside catabolic process GO:0046130 75 0.012
cytokinesis GO:0000910 80 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.012
positive regulation of gtp catabolic process GO:0033126 28 0.012
protein phosphorylation GO:0006468 85 0.012
digestive tract morphogenesis GO:0048546 76 0.012
cellular protein modification process GO:0006464 207 0.012
organic substance transport GO:0071702 113 0.012
response to osmotic stress GO:0006970 29 0.012
positive regulation of hydrolase activity GO:0051345 38 0.012
cell growth GO:0016049 44 0.012
oocyte axis specification GO:0007309 2 0.012
single organism catabolic process GO:0044712 129 0.012
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 2 0.012
defense response to bacterium GO:0042742 86 0.012
positive regulation of phosphate metabolic process GO:0045937 56 0.012
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.012
regulation of catalytic activity GO:0050790 78 0.012
defense response to other organism GO:0098542 100 0.012
nucleoside phosphate catabolic process GO:1901292 77 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.012
phagocytosis engulfment GO:0006911 98 0.012
negative regulation of rna metabolic process GO:0051253 53 0.012
regulation of neurotransmitter levels GO:0001505 36 0.011
synaptic growth at neuromuscular junction GO:0051124 1 0.011
response to other organism GO:0051707 101 0.011
regulation of cell projection organization GO:0031344 38 0.011
synaptic vesicle endocytosis GO:0048488 3 0.011
positive regulation of stress activated mapk cascade GO:0032874 3 0.011
positive regulation of neuron differentiation GO:0045666 4 0.011
regulation of cell size GO:0008361 30 0.011
purine ribonucleotide metabolic process GO:0009150 95 0.011
regeneration GO:0031099 4 0.011
dendrite development GO:0016358 42 0.011
regulation of cellular amine metabolic process GO:0033238 0 0.011
synaptic vesicle recycling GO:0036465 3 0.011
regulation of neurogenesis GO:0050767 40 0.011
establishment or maintenance of cell polarity GO:0007163 63 0.011
multicellular organism growth GO:0035264 385 0.011
macromolecule modification GO:0043412 218 0.011
hyperosmotic response GO:0006972 19 0.011
regulation of cellular ketone metabolic process GO:0010565 3 0.011
neuron projection extension GO:1990138 37 0.011
establishment of synaptic vesicle localization GO:0097480 21 0.011
negative regulation of cell communication GO:0010648 61 0.011
positive regulation of organ growth GO:0046622 4 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.010
molting cycle GO:0042303 281 0.010
male anatomical structure morphogenesis GO:0090598 78 0.010
organelle fission GO:0048285 363 0.010
response to extracellular stimulus GO:0009991 38 0.010
positive regulation of transcription from rna polymerase ii promoter involved in defense response to gram negative bacterium GO:1902097 4 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 28 0.010
cellular amino acid metabolic process GO:0006520 15 0.010
regulation of anatomical structure size GO:0090066 46 0.010
Mouse
regulation of intracellular signal transduction GO:1902531 77 0.010
regulation of hydrolase activity GO:0051336 45 0.010
positive regulation of signaling GO:0023056 66 0.010

max-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.027
disease of cellular proliferation DOID:14566 0 0.027
organ system cancer DOID:0050686 0 0.027
disease of anatomical entity DOID:7 0 0.023
nervous system disease DOID:863 0 0.014