Caenorhabditis elegans

17 known processes

nex-1 (CELE_ZC155.1)

Protein NEX-1

nex-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.432
Worm
embryo development GO:0009790 3052 0.298
Worm
locomotion GO:0040011 1634 0.287
Zebrafish
sexual reproduction GO:0019953 546 0.268
Worm
transport GO:0006810 1093 0.217
multicellular organism reproduction GO:0032504 819 0.208
Worm
meiotic cell cycle GO:0051321 335 0.202
post embryonic development GO:0009791 2152 0.189
developmental process involved in reproduction GO:0003006 1165 0.170
Worm
multi organism reproductive process GO:0044703 867 0.168
Worm
cell cycle process GO:0022402 482 0.125
Human Mouse
regulation of developmental process GO:0050793 684 0.115
reproductive system development GO:0061458 850 0.112
multicellular organismal reproductive process GO:0048609 815 0.110
Worm
regulation of biological quality GO:0065008 741 0.103
Human Mouse
establishment of localization GO:0051234 1171 0.100
cell cycle GO:0007049 526 0.097
Human Mouse
regulation of metabolic process GO:0019222 478 0.089
Human
endocytosis GO:0006897 819 0.089
regulation of multicellular organismal process GO:0051239 726 0.085
Human Mouse
regulation of multicellular organismal development GO:2000026 317 0.080
receptor mediated endocytosis GO:0006898 715 0.079
multicellular organismal aging GO:0010259 812 0.077
maintenance of location GO:0051235 580 0.075
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.074
Worm
lipid localization GO:0010876 573 0.073
Zebrafish Mouse
single organism reproductive process GO:0044702 1196 0.071
Worm
developmental growth GO:0048589 412 0.068
Zebrafish
meiotic nuclear division GO:0007126 300 0.068
reproductive structure development GO:0048608 850 0.066
macromolecule localization GO:0033036 771 0.065
Human Zebrafish Mouse
development of primary sexual characteristics GO:0045137 840 0.065
lipid storage GO:0019915 565 0.065
aging GO:0007568 812 0.063
organelle fission GO:0048285 363 0.063
sex differentiation GO:0007548 909 0.062
gonad development GO:0008406 840 0.061
cellular biosynthetic process GO:0044249 315 0.061
Human
cellular component movement GO:0006928 388 0.060
Zebrafish
cytoskeleton organization GO:0007010 339 0.058
cell development GO:0048468 696 0.057
Human Worm
positive regulation of multicellular organismal process GO:0051240 417 0.057
determination of adult lifespan GO:0008340 812 0.055
regulation of developmental growth GO:0048638 389 0.053
female gamete generation GO:0007292 254 0.051
Worm
biosynthetic process GO:0009058 323 0.051
Human
negative regulation of biological process GO:0048519 567 0.050
Human Mouse
vesicle mediated transport GO:0016192 852 0.048
organic substance biosynthetic process GO:1901576 323 0.046
Human
establishment of localization in cell GO:0051649 318 0.046
Human
regulation of multicellular organism growth GO:0040014 373 0.045
single organism transport GO:0044765 447 0.045
organ development GO:0048513 1102 0.045
Human Mouse
apoptotic process GO:0006915 478 0.045
Mouse
body morphogenesis GO:0010171 620 0.045
regulation of response to stimulus GO:0048583 243 0.043
Mouse
multicellular organism growth GO:0035264 385 0.042
rna metabolic process GO:0016070 228 0.042
Human
germ cell development GO:0007281 351 0.041
Worm
genitalia development GO:0048806 741 0.041
growth GO:0040007 562 0.041
Zebrafish
reproductive behavior GO:0019098 387 0.040
Worm
regulation of growth GO:0040008 409 0.040
multi multicellular organism process GO:0044706 390 0.040
Worm
regulation of cytoplasmic transport GO:1903649 3 0.038
multicellular organismal reproductive behavior GO:0033057 384 0.038
Worm
regulation of vulval development GO:0040028 248 0.038
positive regulation of multicellular organism growth GO:0040018 352 0.038
nucleic acid metabolic process GO:0090304 299 0.038
Human
regulation of nematode larval development GO:0061062 260 0.037
actomyosin structure organization GO:0031032 154 0.037
vulval development GO:0040025 333 0.036
post embryonic organ development GO:0048569 336 0.036
cell motility GO:0048870 313 0.036
Zebrafish
gamete generation GO:0007276 461 0.035
Worm
secretion by cell GO:0032940 138 0.035
Human
positive regulation of developmental growth GO:0048639 354 0.034
positive regulation of growth GO:0045927 369 0.033
behavior GO:0007610 527 0.032
Worm
cell division GO:0051301 262 0.032
Human
organic substance catabolic process GO:1901575 294 0.032
cell migration GO:0016477 306 0.032
membrane organization GO:0061024 135 0.031
multi organism reproductive behavior GO:0044705 387 0.031
Worm
localization of cell GO:0051674 313 0.031
Zebrafish
single organism signaling GO:0044700 401 0.031
Mouse
myofibril assembly GO:0030239 154 0.030
gene expression GO:0010467 412 0.030
Human
positive regulation of developmental process GO:0051094 408 0.030
negative regulation of post embryonic development GO:0048581 208 0.029
hermaphrodite genitalia development GO:0040035 734 0.029
single organism localization GO:1902578 518 0.029
single organism organelle organization GO:1902589 501 0.029
Human
organelle organization GO:0006996 783 0.029
Human
striated muscle cell differentiation GO:0051146 158 0.029
protein complex subunit organization GO:0071822 280 0.028
Human Mouse
cell death GO:0008219 547 0.028
Mouse
negative regulation of macromolecule metabolic process GO:0010605 229 0.028
Human
anatomical structure formation involved in morphogenesis GO:0048646 250 0.027
Human Mouse
cellular component assembly involved in morphogenesis GO:0010927 183 0.027
macromolecule biosynthetic process GO:0009059 250 0.027
Human
negative regulation of gene expression GO:0010629 217 0.027
Human
mitotic spindle organization GO:0007052 81 0.027
lipid metabolic process GO:0006629 77 0.027
regulation of macromolecule metabolic process GO:0060255 421 0.027
Human
regulation of primary metabolic process GO:0080090 292 0.026
Human
neurogenesis GO:0022008 236 0.025
actin cytoskeleton organization GO:0030036 184 0.025
nervous system development GO:0007399 253 0.025
cellular component biogenesis GO:0044085 297 0.025
Human
cellular component morphogenesis GO:0032989 318 0.025
organic acid metabolic process GO:0006082 47 0.025
nucleobase containing compound metabolic process GO:0006139 406 0.025
Human
regulation of biosynthetic process GO:0009889 189 0.024
Human
defense response GO:0006952 296 0.024
negative regulation of vulval development GO:0040027 206 0.024
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.024
Human
single fertilization GO:0007338 61 0.024
regulation of post embryonic development GO:0048580 260 0.024
spindle organization GO:0007051 92 0.024
regulation of cell division GO:0051302 142 0.024
positive regulation of intracellular transport GO:0032388 2 0.024
cellular macromolecule biosynthetic process GO:0034645 247 0.024
Human
signaling GO:0023052 401 0.023
Mouse
oogenesis GO:0048477 229 0.023
Worm
negative regulation of nematode larval development GO:0061064 208 0.021
death GO:0016265 547 0.021
Mouse
macromolecular complex subunit organization GO:0043933 320 0.021
Human Mouse
negative regulation of developmental process GO:0051093 227 0.021
meiotic cell cycle process GO:1903046 170 0.021
nucleobase containing small molecule metabolic process GO:0055086 115 0.021
actin filament based process GO:0030029 191 0.021
posttranscriptional gene silencing by rna GO:0035194 143 0.020
regulation of response to wounding GO:1903034 1 0.020
Mouse
regulation of cellular metabolic process GO:0031323 305 0.020
Human
positive regulation of cellular process GO:0048522 332 0.020
Human Mouse
organelle assembly GO:0070925 214 0.020
cell surface receptor signaling pathway GO:0007166 149 0.020
rna interference GO:0016246 137 0.020
carbohydrate derivative metabolic process GO:1901135 141 0.020
positive regulation of neurogenesis GO:0050769 4 0.020
phosphorus metabolic process GO:0006793 232 0.020
myosin filament assembly GO:0031034 138 0.020
gene silencing GO:0016458 143 0.019
phosphate containing compound metabolic process GO:0006796 232 0.019
muscle structure development GO:0061061 191 0.019
oviposition GO:0018991 364 0.019
Worm
negative regulation of metabolic process GO:0009892 240 0.019
Human
fertilization GO:0009566 63 0.019
multi organism behavior GO:0051705 389 0.019
Worm
gene silencing by rna GO:0031047 143 0.019
cellular macromolecular complex assembly GO:0034622 184 0.019
response to wounding GO:0009611 4 0.018
Zebrafish Mouse
regulation of localization GO:0032879 194 0.018
Human Zebrafish
cellular protein complex assembly GO:0043623 178 0.018
ribonucleoside triphosphate catabolic process GO:0009203 72 0.018
regulation of nitrogen compound metabolic process GO:0051171 222 0.018
Human
organophosphate metabolic process GO:0019637 125 0.018
cellular amino acid metabolic process GO:0006520 15 0.018
myosin filament organization GO:0031033 138 0.018
regulation of transport GO:0051049 91 0.017
Human
cellular component assembly GO:0022607 293 0.017
Human
positive regulation of cellular metabolic process GO:0031325 178 0.017
posttranscriptional gene silencing GO:0016441 143 0.017
membrane invagination GO:0010324 98 0.017
small molecule metabolic process GO:0044281 186 0.016
muscle cell differentiation GO:0042692 171 0.016
establishment of nucleus localization GO:0040023 55 0.016
muscle cell development GO:0055001 158 0.016
regulation of gene expression epigenetic GO:0040029 163 0.016
regulation of signaling GO:0023051 172 0.016
regulation of macromolecule biosynthetic process GO:0010556 189 0.016
Human
cell fate commitment GO:0045165 139 0.016
digestive tract morphogenesis GO:0048546 76 0.016
mitotic cell cycle process GO:1903047 194 0.016
Mouse
carboxylic acid metabolic process GO:0019752 34 0.016
regulation of cell communication GO:0010646 176 0.016
positive regulation of neuron differentiation GO:0045666 4 0.016
heterocycle catabolic process GO:0046700 119 0.015
single organism behavior GO:0044708 83 0.015
oxoacid metabolic process GO:0043436 47 0.015
striated muscle cell development GO:0055002 157 0.015
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.015
Human
positive regulation of macromolecule metabolic process GO:0010604 149 0.015
regulation of cellular component organization GO:0051128 248 0.015
Human
cellular catabolic process GO:0044248 199 0.015
digestive tract development GO:0048565 122 0.015
nucleobase containing compound biosynthetic process GO:0034654 184 0.015
Human
regulation of rna metabolic process GO:0051252 173 0.015
Human
head development GO:0060322 1 0.015
regulation of signal transduction GO:0009966 135 0.014
cellular lipid metabolic process GO:0044255 40 0.014
cellular localization GO:0051641 360 0.014
Human
molting cycle GO:0042303 281 0.014
taxis GO:0042330 128 0.014
regulation of locomotion GO:0040012 161 0.014
Zebrafish
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.014
regulation of synapse assembly GO:0051963 2 0.014
axon development GO:0061564 163 0.014
embryonic morphogenesis GO:0048598 152 0.014
tube development GO:0035295 126 0.014
protein localization GO:0008104 205 0.014
Human
cell morphogenesis involved in differentiation GO:0000904 112 0.014
cellular protein metabolic process GO:0044267 279 0.013
Human
positive regulation of transcription dna templated GO:0045893 102 0.013
protein complex assembly GO:0006461 186 0.013
Human
positive regulation of protein transport GO:0051222 4 0.013
phagocytosis engulfment GO:0006911 98 0.013
organic substance transport GO:0071702 113 0.013
Human Zebrafish Mouse
macromolecular complex assembly GO:0065003 193 0.013
Human
striated muscle myosin thick filament assembly GO:0071688 138 0.013
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.013
Human
aromatic compound catabolic process GO:0019439 116 0.013
nucleus localization GO:0051647 55 0.013
establishment of spindle localization GO:0051293 51 0.013
regulation of molecular function GO:0065009 89 0.013
Human Mouse
transcription from rna polymerase ii promoter GO:0006366 149 0.013
Human
regulation of intracellular signal transduction GO:1902531 77 0.013
digestive system development GO:0055123 122 0.013
positive regulation of cell projection organization GO:0031346 4 0.013
cell type specific apoptotic process GO:0097285 4 0.013
Mouse
regulation of nucleocytoplasmic transport GO:0046822 3 0.013
negative regulation of cellular process GO:0048523 239 0.013
Human
cell proliferation GO:0008283 116 0.013
Mouse
engulfment of apoptotic cell GO:0043652 94 0.013
regulation of cell differentiation GO:0045595 81 0.012
protein complex biogenesis GO:0070271 186 0.012
Human
neuron differentiation GO:0030182 217 0.012
innate immune response GO:0045087 190 0.012
regulation of epithelial cell proliferation GO:0050678 1 0.012
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.012
neuromuscular junction development GO:0007528 2 0.012
regulation of transcription dna templated GO:0006355 164 0.012
Human
cellular response to inorganic substance GO:0071241 3 0.012
negative regulation of multicellular organismal process GO:0051241 236 0.012
Human Mouse
regulation of cellular ketone metabolic process GO:0010565 3 0.012
posttranscriptional regulation of gene expression GO:0010608 166 0.012
regulation of apoptotic signaling pathway GO:2001233 1 0.012
actin cytoskeleton reorganization GO:0031532 4 0.012
response to chemical GO:0042221 356 0.012
Human Mouse
regulation of protein targeting GO:1903533 3 0.012
cuticle development GO:0042335 100 0.012
generation of neurons GO:0048699 235 0.012
intracellular signal transduction GO:0035556 96 0.011
cytokinesis GO:0000910 80 0.011
Human
microtubule based process GO:0007017 182 0.011
organonitrogen compound metabolic process GO:1901564 151 0.011
programmed cell death GO:0012501 500 0.011
Mouse
positive regulation of cell migration GO:0030335 3 0.011
protein oligomerization GO:0051259 4 0.011
Human
tissue development GO:0009888 112 0.011
Human Zebrafish
regulation of gene expression GO:0010468 366 0.011
Human
nuclear migration GO:0007097 54 0.011
inductive cell migration GO:0040039 145 0.011
response to external stimulus GO:0009605 289 0.011
Mouse
positive regulation of epithelial cell proliferation GO:0050679 1 0.011
nucleic acid templated transcription GO:0097659 169 0.011
Human
axonogenesis GO:0007409 102 0.011
ribonucleotide metabolic process GO:0009259 99 0.011
cellular response to abiotic stimulus GO:0071214 4 0.011
system process GO:0003008 136 0.010
Zebrafish Mouse
synaptic transmission GO:0007268 106 0.010
regulation of cellular amine metabolic process GO:0033238 0 0.010
regulation of nucleic acid templated transcription GO:1903506 165 0.010
Human
regulation of meiotic cell cycle GO:0051445 136 0.010
meiotic chromosome segregation GO:0045132 139 0.010
pronuclear migration GO:0035046 51 0.010
establishment of organelle localization GO:0051656 123 0.010
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 2 0.010
single organism biosynthetic process GO:0044711 91 0.010
cation transport GO:0006812 78 0.010
Mouse
skeletal muscle organ development GO:0060538 3 0.010

nex-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.021
nervous system disease DOID:863 0 0.014
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
disease of metabolism DOID:0014667 0 0.010