Caenorhabditis elegans

0 known processes

php-3 (CELE_Y75B8A.1)

Protein PHP-3

php-3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
defense response GO:0006952 296 0.466
embryo development GO:0009790 3052 0.410
Mouse Worm Fly
immune response GO:0006955 192 0.304
aging GO:0007568 812 0.300
muscle structure development GO:0061061 191 0.294
Fly
determination of adult lifespan GO:0008340 812 0.257
multicellular organismal aging GO:0010259 812 0.233
embryo development ending in birth or egg hatching GO:0009792 2992 0.227
Worm
defense response to other organism GO:0098542 100 0.154
multicellular organism reproduction GO:0032504 819 0.139
Fly
cell development GO:0048468 696 0.136
Fly
death GO:0016265 547 0.135
Fly
single organism organelle organization GO:1902589 501 0.125
locomotion GO:0040011 1634 0.119
Worm Fly
innate immune response GO:0045087 190 0.111
multicellular organismal reproductive process GO:0048609 815 0.111
Fly
organelle organization GO:0006996 783 0.106
anatomical structure formation involved in morphogenesis GO:0048646 250 0.097
post embryonic organ development GO:0048569 336 0.092
Worm
post embryonic development GO:0009791 2152 0.091
Worm
cell migration GO:0016477 306 0.091
Fly
cellular component movement GO:0006928 388 0.087
Fly
response to other organism GO:0051707 101 0.085
developmental process involved in reproduction GO:0003006 1165 0.084
Worm Fly
transport GO:0006810 1093 0.082
regulation of post embryonic development GO:0048580 260 0.081
Worm
muscle cell differentiation GO:0042692 171 0.081
phagocytosis GO:0006909 115 0.081
growth GO:0040007 562 0.079
Worm
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.079
Worm
endocytosis GO:0006897 819 0.078
macromolecule localization GO:0033036 771 0.076
lipid localization GO:0010876 573 0.076
response to organic substance GO:0010033 131 0.076
striated muscle cell differentiation GO:0051146 158 0.075
regulation of biological quality GO:0065008 741 0.074
Fly
maintenance of location GO:0051235 580 0.074
lipid storage GO:0019915 565 0.071
molting cycle GO:0042303 281 0.070
Worm
cellular component morphogenesis GO:0032989 318 0.069
catabolic process GO:0009056 318 0.069
body morphogenesis GO:0010171 620 0.067
Worm
cellular response to chemical stimulus GO:0070887 129 0.066
cytoskeleton organization GO:0007010 339 0.065
response to external stimulus GO:0009605 289 0.065
sex differentiation GO:0007548 909 0.065
Worm Fly
signaling GO:0023052 401 0.064
multi organism reproductive process GO:0044703 867 0.063
Fly
regulation of response to stimulus GO:0048583 243 0.063
cellular component assembly involved in morphogenesis GO:0010927 183 0.063
muscle cell development GO:0055001 158 0.063
receptor mediated endocytosis GO:0006898 715 0.062
regulation of multicellular organismal process GO:0051239 726 0.062
Worm Fly
vulval development GO:0040025 333 0.061
Worm
striated muscle cell development GO:0055002 157 0.059
single organism reproductive process GO:0044702 1196 0.059
Fly
response to biotic stimulus GO:0009607 101 0.058
development of primary sexual characteristics GO:0045137 840 0.057
Fly
muscle tissue development GO:0060537 1 0.057
Fly
single organism signaling GO:0044700 401 0.056
cell cycle process GO:0022402 482 0.055
localization of cell GO:0051674 313 0.055
Fly
multi organism reproductive behavior GO:0044705 387 0.054
Fly
multi organism behavior GO:0051705 389 0.054
Fly
regulation of developmental process GO:0050793 684 0.053
Worm Fly
response to chemical GO:0042221 356 0.052
organelle assembly GO:0070925 214 0.052
regulation of signal transduction GO:0009966 135 0.051
organic substance catabolic process GO:1901575 294 0.051
macromolecular complex subunit organization GO:0043933 320 0.050
cellular response to organic substance GO:0071310 119 0.049
regulation of gene expression GO:0010468 366 0.049
Fly
nucleobase containing compound metabolic process GO:0006139 406 0.048
Fly
regulation of cell communication GO:0010646 176 0.047
cell motility GO:0048870 313 0.047
Fly
taxis GO:0042330 128 0.047
regulation of cellular biosynthetic process GO:0031326 189 0.047
Fly
reproductive structure development GO:0048608 850 0.047
Fly
cellular component assembly GO:0022607 293 0.047
reproductive system development GO:0061458 850 0.047
Fly
multi multicellular organism process GO:0044706 390 0.047
Fly
cell fate commitment involved in formation of primary germ layer GO:0060795 33 0.047
actomyosin structure organization GO:0031032 154 0.047
gene expression GO:0010467 412 0.047
Fly
chemotaxis GO:0006935 120 0.046
negative regulation of metabolic process GO:0009892 240 0.046
meiotic nuclear division GO:0007126 300 0.046
organic substance biosynthetic process GO:1901576 323 0.045
Fly
establishment of localization GO:0051234 1171 0.045
female gamete generation GO:0007292 254 0.045
response to external biotic stimulus GO:0043207 101 0.045
transcription dna templated GO:0006351 168 0.045
Fly
cellular protein metabolic process GO:0044267 279 0.045
digestive tract development GO:0048565 122 0.045
striated muscle myosin thick filament assembly GO:0071688 138 0.044
vesicle mediated transport GO:0016192 852 0.044
sexual reproduction GO:0019953 546 0.044
Fly
inductive cell migration GO:0040039 145 0.043
reproductive behavior GO:0019098 387 0.043
Fly
regulation of multicellular organism growth GO:0040014 373 0.043
Worm
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.042
Fly
protein complex subunit organization GO:0071822 280 0.042
multicellular organismal reproductive behavior GO:0033057 384 0.042
Fly
gamete generation GO:0007276 461 0.041
Fly
cellular macromolecular complex assembly GO:0034622 184 0.041
phosphate containing compound metabolic process GO:0006796 232 0.040
actin cytoskeleton organization GO:0030036 184 0.040
myofibril assembly GO:0030239 154 0.039
apoptotic cell clearance GO:0043277 111 0.039
regulation of growth GO:0040008 409 0.038
Worm
ovulation GO:0030728 33 0.038
regulation of metabolic process GO:0019222 478 0.037
Fly
oviposition GO:0018991 364 0.037
positive regulation of developmental process GO:0051094 408 0.037
Worm Fly
digestive tract morphogenesis GO:0048546 76 0.037
cellular component biogenesis GO:0044085 297 0.036
apoptotic process GO:0006915 478 0.035
Fly
regulation of nematode larval development GO:0061062 260 0.035
Worm
signal transduction GO:0007165 317 0.035
cell death GO:0008219 547 0.035
Fly
negative regulation of biological process GO:0048519 567 0.035
Worm Fly
digestive system development GO:0055123 122 0.034
response to wounding GO:0009611 4 0.034
biosynthetic process GO:0009058 323 0.034
Fly
cellular protein complex assembly GO:0043623 178 0.034
myosin filament assembly GO:0031034 138 0.033
posttranscriptional regulation of gene expression GO:0010608 166 0.033
germ cell development GO:0007281 351 0.033
cellular macromolecule biosynthetic process GO:0034645 247 0.033
Fly
hermaphrodite genitalia development GO:0040035 734 0.033
embryonic pattern specification GO:0009880 21 0.033
Worm Fly
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.032
protein metabolic process GO:0019538 422 0.032
regulation of vulval development GO:0040028 248 0.032
Worm
cellular catabolic process GO:0044248 199 0.032
behavior GO:0007610 527 0.032
Fly
regulation of developmental growth GO:0048638 389 0.032
Worm
regulation of macromolecule metabolic process GO:0060255 421 0.031
Fly
cell cycle GO:0007049 526 0.031
multicellular organism growth GO:0035264 385 0.031
Worm
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.030
Fly
embryonic morphogenesis GO:0048598 152 0.030
Mouse Worm
regulation of primary metabolic process GO:0080090 292 0.030
Fly
positive regulation of intracellular signal transduction GO:1902533 24 0.030
oogenesis GO:0048477 229 0.030
gonad development GO:0008406 840 0.029
Fly
collagen and cuticulin based cuticle development GO:0040002 99 0.028
developmental growth GO:0048589 412 0.028
Worm
negative regulation of macromolecule metabolic process GO:0010605 229 0.028
positive regulation of multicellular organism growth GO:0040018 352 0.028
Worm
cell fate commitment GO:0045165 139 0.028
Fly
positive regulation of metabolic process GO:0009893 187 0.028
Fly
organ development GO:0048513 1102 0.027
Worm Fly
positive regulation of developmental growth GO:0048639 354 0.027
Worm
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.027
Fly
intracellular signal transduction GO:0035556 96 0.027
rna biosynthetic process GO:0032774 169 0.027
Fly
meiotic cell cycle GO:0051321 335 0.026
macromolecular complex assembly GO:0065003 193 0.026
cellular protein modification process GO:0006464 207 0.026
phosphorus metabolic process GO:0006793 232 0.026
myosin filament organization GO:0031033 138 0.026
regulation of cellular metabolic process GO:0031323 305 0.026
Fly
actin filament based process GO:0030029 191 0.025
cuticle development GO:0042335 100 0.025
tissue morphogenesis GO:0048729 65 0.025
phagocytosis engulfment GO:0006911 98 0.024
negative regulation of post embryonic development GO:0048581 208 0.024
Worm
single organism localization GO:1902578 518 0.024
protein complex biogenesis GO:0070271 186 0.024
tube development GO:0035295 126 0.024
membrane invagination GO:0010324 98 0.024
cell division GO:0051301 262 0.024
Worm
male sex differentiation GO:0046661 86 0.024
Worm Fly
eating behavior GO:0042755 59 0.024
protein modification process GO:0036211 207 0.023
regulation of multicellular organismal development GO:2000026 317 0.023
Worm Fly
defense response to bacterium GO:0042742 86 0.023
positive regulation of multicellular organismal process GO:0051240 417 0.023
Worm
cellular nitrogen compound biosynthetic process GO:0044271 192 0.023
Fly
mesodermal cell fate specification GO:0007501 13 0.023
positive regulation of response to stimulus GO:0048584 55 0.023
nervous system development GO:0007399 253 0.022
cellular response to stress GO:0033554 162 0.022
cellular biosynthetic process GO:0044249 315 0.022
Fly
positive regulation of growth GO:0045927 369 0.022
Worm
organelle fission GO:0048285 363 0.022
genitalia development GO:0048806 741 0.022
Fly
negative regulation of gene expression GO:0010629 217 0.022
head development GO:0060322 1 0.022
protein localization GO:0008104 205 0.021
organonitrogen compound metabolic process GO:1901564 151 0.021
regulation of rna biosynthetic process GO:2001141 165 0.021
Fly
macromolecule modification GO:0043412 218 0.021
meiotic cell cycle process GO:1903046 170 0.021
cell morphogenesis GO:0000902 163 0.021
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.021
Fly
regulation of locomotion GO:0040012 161 0.021
lamellipodium organization GO:0097581 2 0.021
cell morphogenesis involved in differentiation GO:0000904 112 0.020
positive regulation of rna metabolic process GO:0051254 103 0.020
Fly
nucleic acid metabolic process GO:0090304 299 0.020
Fly
sensory organ morphogenesis GO:0090596 2 0.020
skeletal muscle organ development GO:0060538 3 0.020
programmed cell death GO:0012501 500 0.020
Fly
single organism catabolic process GO:0044712 129 0.020
axonogenesis GO:0007409 102 0.020
cell type specific apoptotic process GO:0097285 4 0.019
muscle organ morphogenesis GO:0048644 4 0.019
axon guidance GO:0007411 82 0.019
positive regulation of cellular process GO:0048522 332 0.019
Fly
macromolecule catabolic process GO:0009057 202 0.019
macromolecule biosynthetic process GO:0009059 250 0.019
Fly
protein complex assembly GO:0006461 186 0.019
rho protein signal transduction GO:0007266 2 0.018
axon development GO:0061564 163 0.018
translation GO:0006412 37 0.018
rna metabolic process GO:0016070 228 0.018
Fly
purine nucleoside metabolic process GO:0042278 92 0.018
regeneration GO:0031099 4 0.018
memory GO:0007613 3 0.018
cellular nitrogen compound catabolic process GO:0044270 119 0.018
purine nucleotide catabolic process GO:0006195 75 0.018
organic cyclic compound catabolic process GO:1901361 119 0.017
cell fate specification involved in pattern specification GO:0060573 4 0.017
intracellular receptor signaling pathway GO:0030522 2 0.017
positive regulation of signal transduction GO:0009967 40 0.017
regulation of transcription dna templated GO:0006355 164 0.017
Fly
development of primary male sexual characteristics GO:0046546 4 0.017
Fly
pattern specification process GO:0007389 59 0.017
Mouse Worm Fly
cell projection organization GO:0030030 231 0.017
axis specification GO:0009798 23 0.017
positive regulation of cellular metabolic process GO:0031325 178 0.017
Fly
neurogenesis GO:0022008 236 0.016
response to temperature stimulus GO:0009266 66 0.016
single organism transport GO:0044765 447 0.016
engulfment of apoptotic cell GO:0043652 94 0.016
cell growth GO:0016049 44 0.016
gene silencing by rna GO:0031047 143 0.016
positive regulation of nucleic acid templated transcription GO:1903508 102 0.016
Fly
spindle organization GO:0007051 92 0.016
cytokinesis GO:0000910 80 0.015
cell surface receptor signaling pathway GO:0007166 149 0.015
adult behavior GO:0030534 3 0.015
phosphorylation GO:0016310 116 0.015
glutathione metabolic process GO:0006749 2 0.015
protein catabolic process GO:0030163 162 0.015
ribonucleoprotein complex assembly GO:0022618 4 0.015
gastrulation GO:0007369 58 0.015
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.015
Fly
nucleoside metabolic process GO:0009116 99 0.015
neuron projection guidance GO:0097485 82 0.015
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.015
Fly
cell substrate adhesion GO:0031589 1 0.015
nucleoside phosphate catabolic process GO:1901292 77 0.015
nematode male tail tip morphogenesis GO:0045138 77 0.015
Worm
small molecule metabolic process GO:0044281 186 0.015
neuron projection morphogenesis GO:0048812 114 0.015
organic substance transport GO:0071702 113 0.014
regulation of macromolecule biosynthetic process GO:0010556 189 0.014
Fly
defense response to fungus GO:0050832 19 0.014
adult locomotory behavior GO:0008344 1 0.014
rna interference GO:0016246 137 0.014
male anatomical structure morphogenesis GO:0090598 78 0.014
Worm
ribonucleoside metabolic process GO:0009119 98 0.014
transcription from rna polymerase ii promoter GO:0006366 149 0.014
Fly
negative regulation of cellular biosynthetic process GO:0031327 65 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.013
Fly
cell projection assembly GO:0030031 35 0.013
cellular amino acid metabolic process GO:0006520 15 0.013
muscle attachment GO:0016203 3 0.013
organic acid metabolic process GO:0006082 47 0.013
carbohydrate derivative catabolic process GO:1901136 82 0.013
regulation of reproductive process GO:2000241 66 0.013
negative regulation of vulval development GO:0040027 206 0.013
Worm
tissue development GO:0009888 112 0.013
Fly
regulation of multi organism process GO:0043900 69 0.013
pigment metabolic process GO:0042440 2 0.012
positive regulation of macromolecule metabolic process GO:0010604 149 0.012
Fly
regulation of cytoplasmic transport GO:1903649 3 0.012
pharynx development GO:0060465 51 0.012
regulation of nitrogen compound metabolic process GO:0051171 222 0.012
Fly
nucleobase containing compound biosynthetic process GO:0034654 184 0.012
Fly
membrane organization GO:0061024 135 0.012
negative regulation of cellular process GO:0048523 239 0.012
Fly
organophosphate metabolic process GO:0019637 125 0.012
mesoderm morphogenesis GO:0048332 24 0.012
ras protein signal transduction GO:0007265 31 0.012
oxoacid metabolic process GO:0043436 47 0.012
carboxylic acid metabolic process GO:0019752 34 0.012
purine ribonucleoside metabolic process GO:0046128 92 0.012
regulation of gene expression epigenetic GO:0040029 163 0.012
regulation of intracellular signal transduction GO:1902531 77 0.012
posttranscriptional gene silencing GO:0016441 143 0.012
posttranscriptional gene silencing by rna GO:0035194 143 0.012
aromatic compound catabolic process GO:0019439 116 0.012
positive regulation of gene expression GO:0010628 112 0.012
Fly
neuron projection development GO:0031175 187 0.012
gene silencing GO:0016458 143 0.012
organophosphate catabolic process GO:0046434 81 0.012
regulation of organ morphogenesis GO:2000027 4 0.012
nucleotide catabolic process GO:0009166 77 0.012
negative regulation of developmental process GO:0051093 227 0.012
Worm Fly
negative regulation of rna metabolic process GO:0051253 53 0.012
lipid metabolic process GO:0006629 77 0.012
regulation of nucleocytoplasmic transport GO:0046822 3 0.012
cell part morphogenesis GO:0032990 152 0.012
regulation of stem cell differentiation GO:2000736 1 0.012
Fly
oxidation reduction process GO:0055114 59 0.011
tube morphogenesis GO:0035239 79 0.011
ribosome biogenesis GO:0042254 4 0.011
nucleobase containing small molecule metabolic process GO:0055086 115 0.011
regulation of cellular catabolic process GO:0031329 51 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.011
guanosine containing compound catabolic process GO:1901069 48 0.011
mesodermal cell differentiation GO:0048333 15 0.011
axonal fasciculation GO:0007413 79 0.011
cell recognition GO:0008037 85 0.011
germ line sex determination GO:0018992 51 0.011
glycosyl compound metabolic process GO:1901657 100 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.011
negative regulation of transcription dna templated GO:0045892 53 0.011
neuron differentiation GO:0030182 217 0.011
response to unfolded protein GO:0006986 71 0.011
pigmentation GO:0043473 2 0.011
Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.011
Fly
carbohydrate derivative metabolic process GO:1901135 141 0.011
rrna metabolic process GO:0016072 3 0.011
negative regulation of gene expression epigenetic GO:0045814 2 0.011
sex determination GO:0007530 60 0.010
generation of neurons GO:0048699 235 0.010
negative regulation of biosynthetic process GO:0009890 65 0.010
regulation of signaling GO:0023051 172 0.010
response to heat GO:0009408 50 0.010
response to topologically incorrect protein GO:0035966 82 0.010
regulation of protein stability GO:0031647 3 0.010
response to endoplasmic reticulum stress GO:0034976 71 0.010
positive regulation of cell migration GO:0030335 3 0.010
actin cytoskeleton reorganization GO:0031532 4 0.010
cellular response to topologically incorrect protein GO:0035967 76 0.010
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.010
nucleoside catabolic process GO:0009164 78 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.010

php-3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.021
nervous system disease DOID:863 0 0.010