Caenorhabditis elegans

72 known processes

uaf-1 (CELE_Y92C3B.2)

Protein UAF-1

uaf-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cell cycle GO:0051726 194 0.570
locomotion GO:0040011 1634 0.476
mitotic cell cycle process GO:1903047 194 0.410
Fly
positive regulation of macromolecule metabolic process GO:0010604 149 0.377
Human
embryo development GO:0009790 3052 0.362
single organism reproductive process GO:0044702 1196 0.339
cell cycle GO:0007049 526 0.332
regulation of multicellular organismal development GO:2000026 317 0.300
negative regulation of metabolic process GO:0009892 240 0.287
Human
hermaphrodite genitalia development GO:0040035 734 0.279
rna metabolic process GO:0016070 228 0.276
Human Mouse Fly
regulation of macromolecule metabolic process GO:0060255 421 0.262
Human Fly
regulation of metabolic process GO:0019222 478 0.259
Human Fly
genitalia development GO:0048806 741 0.234
gonad development GO:0008406 840 0.227
multicellular organismal reproductive process GO:0048609 815 0.219
positive regulation of metabolic process GO:0009893 187 0.205
Human
regulation of meiotic cell cycle GO:0051445 136 0.204
positive regulation of cellular process GO:0048522 332 0.201
Human
reproductive system development GO:0061458 850 0.196
germ cell development GO:0007281 351 0.184
regulation of cellular component organization GO:0051128 248 0.184
phosphorus metabolic process GO:0006793 232 0.168
determination of adult lifespan GO:0008340 812 0.164
cell development GO:0048468 696 0.156
post embryonic development GO:0009791 2152 0.152
regulation of protein catabolic process GO:0042176 13 0.151
programmed cell death GO:0012501 500 0.151
reproductive structure development GO:0048608 850 0.150
generation of neurons GO:0048699 235 0.143
regulation of cell division GO:0051302 142 0.137
regulation of phosphate metabolic process GO:0019220 81 0.136
phosphate containing compound metabolic process GO:0006796 232 0.136
cellular protein modification process GO:0006464 207 0.134
nucleic acid metabolic process GO:0090304 299 0.131
Human Mouse Fly
protein modification process GO:0036211 207 0.130
gene silencing GO:0016458 143 0.129
multicellular organismal aging GO:0010259 812 0.129
regulation of cell cycle process GO:0010564 145 0.128
regulation of phosphorus metabolic process GO:0051174 81 0.126
macromolecule modification GO:0043412 218 0.120
regulation of nucleic acid templated transcription GO:1903506 165 0.119
organelle fission GO:0048285 363 0.119
meiotic cell cycle GO:0051321 335 0.117
regulation of rna metabolic process GO:0051252 173 0.116
Human Fly
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.115
organic substance biosynthetic process GO:1901576 323 0.112
organ development GO:0048513 1102 0.110
regulation of meiosis GO:0040020 94 0.107
neuron development GO:0048666 199 0.107
cell projection organization GO:0030030 231 0.107
body morphogenesis GO:0010171 620 0.106
meiotic nuclear division GO:0007126 300 0.105
positive regulation of chromosome organization GO:2001252 2 0.105
multicellular organism reproduction GO:0032504 819 0.105
regulation of nitrogen compound metabolic process GO:0051171 222 0.102
Human Fly
oocyte construction GO:0007308 2 0.102
protein metabolic process GO:0019538 422 0.100
transport GO:0006810 1093 0.099
Fly
organic cyclic compound biosynthetic process GO:1901362 195 0.096
macromolecule localization GO:0033036 771 0.095
Fly
cellular nitrogen compound biosynthetic process GO:0044271 192 0.094
sex differentiation GO:0007548 909 0.094
female gamete generation GO:0007292 254 0.092
positive regulation of cellular metabolic process GO:0031325 178 0.092
Human
macromolecule catabolic process GO:0009057 202 0.091
organelle organization GO:0006996 783 0.091
neurogenesis GO:0022008 236 0.090
Fly
spindle organization GO:0007051 92 0.087
Fly
nervous system development GO:0007399 253 0.086
Fly
regulation of gene expression GO:0010468 366 0.086
Human Fly
regulation of cytoplasmic transport GO:1903649 3 0.086
Fly
chromosome organization GO:0051276 104 0.085
protein localization GO:0008104 205 0.084
regulation of molecular function GO:0065009 89 0.084
aromatic compound biosynthetic process GO:0019438 192 0.083
regulation of transcription dna templated GO:0006355 164 0.081
developmental process involved in reproduction GO:0003006 1165 0.081
regulation of rna biosynthetic process GO:2001141 165 0.080
transcription dna templated GO:0006351 168 0.079
receptor mediated endocytosis GO:0006898 715 0.079
regulation of biological quality GO:0065008 741 0.079
cellular protein metabolic process GO:0044267 279 0.078
catabolic process GO:0009056 318 0.078
cellular macromolecule biosynthetic process GO:0034645 247 0.077
regulation of nucleocytoplasmic transport GO:0046822 3 0.077
Fly
establishment of localization GO:0051234 1171 0.076
Fly
apoptotic process GO:0006915 478 0.076
behavior GO:0007610 527 0.074
positive regulation of cell cycle GO:0045787 55 0.073
covalent chromatin modification GO:0016569 30 0.072
transcription from rna polymerase ii promoter GO:0006366 149 0.071
vulval development GO:0040025 333 0.070
cellular biosynthetic process GO:0044249 315 0.070
embryo development ending in birth or egg hatching GO:0009792 2992 0.068
rna localization GO:0006403 3 0.068
Fly
cell division GO:0051301 262 0.068
cell cycle process GO:0022402 482 0.067
neuron projection development GO:0031175 187 0.067
regulation of cell differentiation GO:0045595 81 0.067
cellular nitrogen compound catabolic process GO:0044270 119 0.067
cellular localization GO:0051641 360 0.066
Fly
regulation of organelle organization GO:0033043 164 0.066
gamete generation GO:0007276 461 0.065
cellular component movement GO:0006928 388 0.065
positive regulation of signaling GO:0023056 66 0.065
lipid storage GO:0019915 565 0.065
positive regulation of developmental process GO:0051094 408 0.064
regulation of catabolic process GO:0009894 57 0.064
signal transduction GO:0007165 317 0.064
heterocycle biosynthetic process GO:0018130 187 0.063
multi organism behavior GO:0051705 389 0.062
negative regulation of biological process GO:0048519 567 0.062
Human
regulation of response to stimulus GO:0048583 243 0.061
chromatin organization GO:0006325 32 0.061
establishment of localization in cell GO:0051649 318 0.060
Fly
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.059
cell cell signaling GO:0007267 118 0.059
response to external stimulus GO:0009605 289 0.059
regulation of nuclear division GO:0051783 115 0.059
organonitrogen compound biosynthetic process GO:1901566 44 0.059
neuron differentiation GO:0030182 217 0.058
oocyte axis specification GO:0007309 2 0.058
regulation of protein metabolic process GO:0051246 81 0.058
aging GO:0007568 812 0.057
negative regulation of cell cycle GO:0045786 53 0.057
regulation of cellular catabolic process GO:0031329 51 0.056
positive regulation of phosphate metabolic process GO:0045937 56 0.056
gene silencing by rna GO:0031047 143 0.055
organonitrogen compound metabolic process GO:1901564 151 0.055
rrna metabolic process GO:0016072 3 0.055
regulation of mitotic cell cycle GO:0007346 76 0.054
growth GO:0040007 562 0.054
endocytosis GO:0006897 819 0.054
positive regulation of molecular function GO:0044093 61 0.053
mrna metabolic process GO:0016071 31 0.053
Human Fly
organic substance catabolic process GO:1901575 294 0.052
cellular protein catabolic process GO:0044257 37 0.052
maintenance of location GO:0051235 580 0.052
regulation of cellular metabolic process GO:0031323 305 0.052
Human Fly
response to abiotic stimulus GO:0009628 152 0.051
single organism transport GO:0044765 447 0.051
regulation of primary metabolic process GO:0080090 292 0.050
Human Fly
negative regulation of gene expression GO:0010629 217 0.050
Human
protein catabolic process GO:0030163 162 0.050
regulation of chromosome organization GO:0033044 20 0.049
axonogenesis GO:0007409 102 0.049
posttranscriptional gene silencing by rna GO:0035194 143 0.048
neuron projection morphogenesis GO:0048812 114 0.048
sexual reproduction GO:0019953 546 0.047
regulation of cell communication GO:0010646 176 0.046
lipid localization GO:0010876 573 0.046
death GO:0016265 547 0.046
oogenesis GO:0048477 229 0.046
multi organism reproductive process GO:0044703 867 0.045
regulation of growth GO:0040008 409 0.045
positive regulation of protein metabolic process GO:0051247 45 0.044
post embryonic organ development GO:0048569 336 0.044
posttranscriptional gene silencing GO:0016441 143 0.043
regulation of biosynthetic process GO:0009889 189 0.043
gene expression GO:0010467 412 0.043
Human Mouse Fly
histone modification GO:0016570 30 0.042
nucleobase containing compound biosynthetic process GO:0034654 184 0.042
tissue development GO:0009888 112 0.041
regulation of vulval development GO:0040028 248 0.040
regulation of cell proliferation GO:0042127 105 0.039
regulation of developmental process GO:0050793 684 0.039
positive regulation of signal transduction GO:0009967 40 0.039
negative regulation of catabolic process GO:0009895 9 0.039
negative regulation of macromolecule metabolic process GO:0010605 229 0.038
Human
organic acid metabolic process GO:0006082 47 0.038
positive regulation of multicellular organism growth GO:0040018 352 0.037
vesicle mediated transport GO:0016192 852 0.037
cell cycle phase transition GO:0044770 19 0.037
regulation of hydrolase activity GO:0051336 45 0.036
positive regulation of growth GO:0045927 369 0.036
regulation of nematode larval development GO:0061062 260 0.036
positive regulation of catalytic activity GO:0043085 59 0.036
cell part morphogenesis GO:0032990 152 0.036
organic substance transport GO:0071702 113 0.036
Fly
negative regulation of cellular component organization GO:0051129 33 0.036
mitotic sister chromatid segregation GO:0000070 38 0.035
multicellular organismal reproductive behavior GO:0033057 384 0.034
cellular macromolecule localization GO:0070727 75 0.034
positive regulation of protein catabolic process GO:0045732 6 0.034
chromosome segregation GO:0007059 180 0.034
positive regulation of catabolic process GO:0009896 38 0.034
biosynthetic process GO:0009058 323 0.034
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.034
macromolecular complex subunit organization GO:0043933 320 0.033
Fly
regulation of signaling GO:0023051 172 0.033
positive regulation of developmental growth GO:0048639 354 0.033
rna biosynthetic process GO:0032774 169 0.033
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.033
Human Fly
positive regulation of intracellular transport GO:0032388 2 0.033
Fly
negative regulation of cellular process GO:0048523 239 0.033
Human
cellular protein localization GO:0034613 75 0.033
cellular response to dna damage stimulus GO:0006974 41 0.032
regulation of cellular localization GO:0060341 42 0.032
Fly
regulation of developmental growth GO:0048638 389 0.032
cell migration GO:0016477 306 0.032
cell morphogenesis GO:0000902 163 0.032
carbohydrate derivative metabolic process GO:1901135 141 0.032
cellular component morphogenesis GO:0032989 318 0.032
cellular response to stress GO:0033554 162 0.031
metaphase anaphase transition of cell cycle GO:0044784 15 0.031
developmental growth GO:0048589 412 0.031
regulation of purine nucleotide metabolic process GO:1900542 37 0.031
positive regulation of hydrolase activity GO:0051345 38 0.031
negative regulation of mitotic cell cycle GO:0045930 42 0.030
pole plasm assembly GO:0007315 2 0.030
single organism biosynthetic process GO:0044711 91 0.030
regulation of multicellular organism growth GO:0040014 373 0.030
single organism carbohydrate metabolic process GO:0044723 29 0.029
posttranscriptional regulation of gene expression GO:0010608 166 0.029
localization of cell GO:0051674 313 0.029
single organism behavior GO:0044708 83 0.028
nucleobase containing compound metabolic process GO:0006139 406 0.028
Human Mouse Fly
regulation of cellular amino acid metabolic process GO:0006521 0 0.028
negative regulation of developmental process GO:0051093 227 0.028
rna interference GO:0016246 137 0.028
positive regulation of cellular protein catabolic process GO:1903364 3 0.028
sister chromatid segregation GO:0000819 46 0.028
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 5 0.028
inductive cell migration GO:0040039 145 0.028
oxoacid metabolic process GO:0043436 47 0.027
signaling GO:0023052 401 0.027
positive regulation of phosphorus metabolic process GO:0010562 56 0.027
negative regulation of cellular catabolic process GO:0031330 9 0.027
defense response GO:0006952 296 0.027
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.027
multicellular organism growth GO:0035264 385 0.027
maintenance of protein location GO:0045185 15 0.027
regulation of cell migration GO:0030334 55 0.027
cell growth GO:0016049 44 0.027
axon development GO:0061564 163 0.026
meiotic chromosome segregation GO:0045132 139 0.026
cellular catabolic process GO:0044248 199 0.026
regulation of multicellular organismal process GO:0051239 726 0.026
positive regulation of cellular catabolic process GO:0031331 35 0.026
cellular response to abiotic stimulus GO:0071214 4 0.025
cell death GO:0008219 547 0.025
oocyte development GO:0048599 44 0.025
cell projection morphogenesis GO:0048858 148 0.024
multi multicellular organism process GO:0044706 390 0.024
single organism localization GO:1902578 518 0.024
purine nucleoside triphosphate catabolic process GO:0009146 72 0.023
protein phosphorylation GO:0006468 85 0.023
heterocycle catabolic process GO:0046700 119 0.023
oviposition GO:0018991 364 0.023
dna metabolic process GO:0006259 74 0.023
cell cycle switching mitotic to meiotic cell cycle GO:0051728 35 0.023
modification dependent macromolecule catabolic process GO:0043632 32 0.023
positive regulation of ras protein signal transduction GO:0046579 7 0.022
cell proliferation GO:0008283 116 0.022
regulation of macromolecule biosynthetic process GO:0010556 189 0.022
cell morphogenesis involved in differentiation GO:0000904 112 0.022
regulation of atp catabolic process GO:1903289 3 0.022
spermatogenesis GO:0007283 41 0.022
single organism intracellular transport GO:1902582 70 0.022
phosphorylation GO:0016310 116 0.022
single organism organelle organization GO:1902589 501 0.022
Fly
head development GO:0060322 1 0.021
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.021
Human
cellular response to inorganic substance GO:0071241 3 0.021
regulation of signal transduction GO:0009966 135 0.021
cellular amino acid metabolic process GO:0006520 15 0.021
intracellular transport GO:0046907 77 0.021
Fly
cellular component assembly GO:0022607 293 0.021
multi organism reproductive behavior GO:0044705 387 0.021
positive regulation of cell death GO:0010942 38 0.021
adult behavior GO:0030534 3 0.021
regulation of protein targeting GO:1903533 3 0.021
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.021
organic cyclic compound catabolic process GO:1901361 119 0.021
carboxylic acid metabolic process GO:0019752 34 0.021
protein import GO:0017038 9 0.021
reproductive behavior GO:0019098 387 0.020
regulation of catalytic activity GO:0050790 78 0.020
proteasomal protein catabolic process GO:0010498 20 0.020
nucleobase containing compound catabolic process GO:0034655 114 0.020
meiotic cell cycle process GO:1903046 170 0.020
protein deubiquitination GO:0016579 2 0.019
ubiquitin dependent protein catabolic process GO:0006511 32 0.019
cellular macromolecule catabolic process GO:0044265 73 0.019
muscle structure development GO:0061061 191 0.019
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 1 0.019
positive regulation of proteasomal protein catabolic process GO:1901800 1 0.019
defense response to other organism GO:0098542 100 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 32 0.019
mrna catabolic process GO:0006402 16 0.019
cell recognition GO:0008037 85 0.019
mitotic nuclear division GO:0007067 89 0.019
amine metabolic process GO:0009308 15 0.019
response to chemical GO:0042221 356 0.018
positive regulation of multicellular organismal process GO:0051240 417 0.018
development of primary sexual characteristics GO:0045137 840 0.018
cell motility GO:0048870 313 0.018
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.018
ribosome biogenesis GO:0042254 4 0.018
single organism cellular localization GO:1902580 72 0.018
cellular response to organic substance GO:0071310 119 0.018
small molecule metabolic process GO:0044281 186 0.018
regulation of cellular ketone metabolic process GO:0010565 3 0.018
signal transduction by phosphorylation GO:0023014 31 0.018
cellular component biogenesis GO:0044085 297 0.017
regulation of chromatin modification GO:1903308 2 0.017
mapk cascade GO:0000165 31 0.017
regulation of cellular amine metabolic process GO:0033238 0 0.017
positive regulation of rna biosynthetic process GO:1902680 102 0.017
regulation of protein import into nucleus GO:0042306 3 0.017
nucleic acid templated transcription GO:0097659 169 0.016
negative regulation of protein metabolic process GO:0051248 27 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.016
neuron recognition GO:0008038 83 0.016
positive regulation of gene expression GO:0010628 112 0.016
Human
germ line sex determination GO:0018992 51 0.016
regulation of gene expression epigenetic GO:0040029 163 0.016
intracellular signal transduction GO:0035556 96 0.015
protein complex subunit organization GO:0071822 280 0.015
Fly
neuromuscular junction development GO:0007528 2 0.015
cellular homeostasis GO:0019725 22 0.015
g1 s transition of mitotic cell cycle GO:0000082 2 0.015
translation GO:0006412 37 0.015
proteolysis GO:0006508 61 0.015
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 4 0.015
spindle checkpoint GO:0031577 4 0.015
positive regulation of small gtpase mediated signal transduction GO:0051057 7 0.015
regulation of locomotion GO:0040012 161 0.015
nucleotide metabolic process GO:0009117 108 0.015
mitotic cell cycle checkpoint GO:0007093 5 0.015
negative regulation of multicellular organismal process GO:0051241 236 0.015
positive regulation of meiotic cell cycle GO:0051446 47 0.015
homeostatic process GO:0042592 51 0.015
response to heat GO:0009408 50 0.014
regulation of protein localization GO:0032880 50 0.014
regulation of nucleotide catabolic process GO:0030811 35 0.014
positive regulation of cell communication GO:0010647 69 0.014
macromolecule biosynthetic process GO:0009059 250 0.014
cellular ketone metabolic process GO:0042180 14 0.014
tissue morphogenesis GO:0048729 65 0.014
male gamete generation GO:0048232 41 0.014
oocyte differentiation GO:0009994 45 0.014
negative regulation of cellular protein catabolic process GO:1903363 4 0.014
positive regulation of protein transport GO:0051222 4 0.014
regulation of phosphorylation GO:0042325 45 0.013
regionalization GO:0003002 31 0.013
mitotic spindle organization GO:0007052 81 0.013
Fly
myosin filament organization GO:0031033 138 0.013
positive regulation of response to stimulus GO:0048584 55 0.013
alternative mrna splicing via spliceosome GO:0000380 7 0.013
Fly
organelle assembly GO:0070925 214 0.013
peptidyl amino acid modification GO:0018193 58 0.013
negative regulation of nuclear division GO:0051784 6 0.013
purine ribonucleoside catabolic process GO:0046130 75 0.012
modification dependent protein catabolic process GO:0019941 32 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 20 0.012
negative regulation of response to external stimulus GO:0032102 3 0.012
internal peptidyl lysine acetylation GO:0018393 3 0.012
glycosyl compound metabolic process GO:1901657 100 0.012
response to external biotic stimulus GO:0043207 101 0.012
axonal fasciculation GO:0007413 79 0.012
anatomical structure formation involved in morphogenesis GO:0048646 250 0.012
sex determination GO:0007530 60 0.012
regulation of cellular protein metabolic process GO:0032268 75 0.012
positive regulation of nucleotide catabolic process GO:0030813 28 0.012
rna splicing via transesterification reactions GO:0000375 8 0.012
Human Fly
regulation of histone modification GO:0031056 1 0.012
organophosphate catabolic process GO:0046434 81 0.011
negative regulation of vulval development GO:0040027 206 0.011
positive regulation of transcription dna templated GO:0045893 102 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 28 0.011
regulation of protein stability GO:0031647 3 0.011
response to extracellular stimulus GO:0009991 38 0.011
negative regulation of neurogenesis GO:0050768 4 0.011
positive regulation of chromatin modification GO:1903310 1 0.011
neuron projection guidance GO:0097485 82 0.011
positive regulation of rna metabolic process GO:0051254 103 0.011
Human
single organism catabolic process GO:0044712 129 0.011
carbohydrate derivative biosynthetic process GO:1901137 46 0.011
positive regulation of protein modification process GO:0031401 29 0.011
regulation of proteasomal protein catabolic process GO:0061136 5 0.011
protein oligomerization GO:0051259 4 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.011
Human
immune response GO:0006955 192 0.011
protein complex biogenesis GO:0070271 186 0.011
negative regulation of mitotic metaphase anaphase transition GO:0045841 4 0.011
positive regulation of phosphorylation GO:0042327 27 0.011
regulation of mapk cascade GO:0043408 23 0.011
cellular lipid metabolic process GO:0044255 40 0.010
negative regulation of cellular metabolic process GO:0031324 95 0.010
Human
rna catabolic process GO:0006401 21 0.010
hermaphrodite germ line sex determination GO:0040021 48 0.010
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.010
positive regulation of biosynthetic process GO:0009891 109 0.010
macroautophagy GO:0016236 11 0.010

uaf-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.034
nervous system disease DOID:863 0 0.012