Caenorhabditis elegans

28 known processes

imb-3 (CELE_C53D5.6)

Protein IMB-3

imb-3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.877
single organism reproductive process GO:0044702 1196 0.785
endocytosis GO:0006897 819 0.699
embryo development ending in birth or egg hatching GO:0009792 2992 0.679
sex differentiation GO:0007548 909 0.564
developmental process involved in reproduction GO:0003006 1165 0.549
reproductive structure development GO:0048608 850 0.542
receptor mediated endocytosis GO:0006898 715 0.517
vesicle mediated transport GO:0016192 852 0.514
reproductive system development GO:0061458 850 0.480
development of primary sexual characteristics GO:0045137 840 0.450
hermaphrodite genitalia development GO:0040035 734 0.445
translational initiation GO:0006413 2 0.380
genitalia development GO:0048806 741 0.372
oocyte construction GO:0007308 2 0.343
establishment of localization GO:0051234 1171 0.339
organ development GO:0048513 1102 0.323
locomotion GO:0040011 1634 0.320
gonad development GO:0008406 840 0.318
cell cycle process GO:0022402 482 0.316
Yeast
cellular protein metabolic process GO:0044267 279 0.307
Yeast
gene expression GO:0010467 412 0.303
Yeast
cellular component biogenesis GO:0044085 297 0.302
cell cycle GO:0007049 526 0.299
Yeast
organelle organization GO:0006996 783 0.294
Yeast
protein complex subunit organization GO:0071822 280 0.287
oocyte axis specification GO:0007309 2 0.280
translation GO:0006412 37 0.253
signaling GO:0023052 401 0.251
transport GO:0006810 1093 0.245
multi organism reproductive process GO:0044703 867 0.235
multicellular organism reproduction GO:0032504 819 0.227
macromolecular complex subunit organization GO:0043933 320 0.219
mitotic cell cycle process GO:1903047 194 0.217
Yeast
biosynthetic process GO:0009058 323 0.212
cellular component assembly GO:0022607 293 0.194
negative regulation of metabolic process GO:0009892 240 0.192
apoptotic process GO:0006915 478 0.190
gamete generation GO:0007276 461 0.189
rna metabolic process GO:0016070 228 0.189
sexual reproduction GO:0019953 546 0.186
positive regulation of metabolic process GO:0009893 187 0.181
multicellular organismal reproductive process GO:0048609 815 0.180
cellular biosynthetic process GO:0044249 315 0.179
pole plasm assembly GO:0007315 2 0.175
cellular macromolecule biosynthetic process GO:0034645 247 0.170
single organism organelle organization GO:1902589 501 0.169
Yeast
organic substance biosynthetic process GO:1901576 323 0.157
negative regulation of biological process GO:0048519 567 0.157
cell projection organization GO:0030030 231 0.154
body morphogenesis GO:0010171 620 0.151
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.148
regulation of metabolic process GO:0019222 478 0.145
Yeast
positive regulation of cellular metabolic process GO:0031325 178 0.143
neuron differentiation GO:0030182 217 0.141
protein metabolic process GO:0019538 422 0.141
Yeast
oocyte development GO:0048599 44 0.140
oogenesis GO:0048477 229 0.135
single fertilization GO:0007338 61 0.134
anatomical structure formation involved in morphogenesis GO:0048646 250 0.134
cell death GO:0008219 547 0.123
death GO:0016265 547 0.122
cellular component morphogenesis GO:0032989 318 0.117
female gamete generation GO:0007292 254 0.116
establishment of localization in cell GO:0051649 318 0.112
Human Yeast Mouse
regulation of developmental process GO:0050793 684 0.111
cellular macromolecular complex assembly GO:0034622 184 0.110
macromolecule biosynthetic process GO:0009059 250 0.103
muscle tissue development GO:0060537 1 0.101
gene silencing GO:0016458 143 0.100
fertilization GO:0009566 63 0.100
catabolic process GO:0009056 318 0.098
nucleobase containing compound metabolic process GO:0006139 406 0.097
cell development GO:0048468 696 0.097
nucleic acid metabolic process GO:0090304 299 0.096
regulation of gene expression epigenetic GO:0040029 163 0.096
posttranscriptional gene silencing GO:0016441 143 0.095
posttranscriptional regulation of gene expression GO:0010608 166 0.092
negative regulation of cellular process GO:0048523 239 0.091
negative regulation of gene expression GO:0010629 217 0.089
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.089
establishment of spindle localization GO:0051293 51 0.087
neuron projection development GO:0031175 187 0.085
single organism transport GO:0044765 447 0.085
Human Yeast Mouse
cellular response to chemical stimulus GO:0070887 129 0.084
Mouse
post embryonic development GO:0009791 2152 0.083
tissue development GO:0009888 112 0.082
positive regulation of gene expression GO:0010628 112 0.081
oocyte differentiation GO:0009994 45 0.080
regulation of protein metabolic process GO:0051246 81 0.080
Yeast
cellular nitrogen compound catabolic process GO:0044270 119 0.079
regulation of biological quality GO:0065008 741 0.078
regulation of gene expression GO:0010468 366 0.077
macromolecular complex assembly GO:0065003 193 0.076
macromolecule catabolic process GO:0009057 202 0.076
cell projection morphogenesis GO:0048858 148 0.076
multicellular organismal aging GO:0010259 812 0.076
striated muscle cell differentiation GO:0051146 158 0.075
protein complex biogenesis GO:0070271 186 0.075
phosphorus metabolic process GO:0006793 232 0.073
gene silencing by rna GO:0031047 143 0.072
single organism localization GO:1902578 518 0.071
Human Yeast Mouse
actin cytoskeleton organization GO:0030036 184 0.070
protein complex assembly GO:0006461 186 0.069
positive regulation of macromolecule metabolic process GO:0010604 149 0.069
posttranscriptional gene silencing by rna GO:0035194 143 0.067
regulation of multicellular organismal development GO:2000026 317 0.067
cellular catabolic process GO:0044248 199 0.066
neuron projection morphogenesis GO:0048812 114 0.065
macromolecule localization GO:0033036 771 0.065
Human Yeast Mouse
negative regulation of developmental process GO:0051093 227 0.063
regulation of macromolecule biosynthetic process GO:0010556 189 0.063
negative regulation of vulval development GO:0040027 206 0.061
cytoskeleton organization GO:0007010 339 0.060
positive regulation of rna metabolic process GO:0051254 103 0.059
neurogenesis GO:0022008 236 0.058
lipid storage GO:0019915 565 0.058
rna interference GO:0016246 137 0.058
meiotic cell cycle process GO:1903046 170 0.058
regulation of multicellular organismal process GO:0051239 726 0.058
muscle cell differentiation GO:0042692 171 0.057
cellular response to stress GO:0033554 162 0.057
lipid localization GO:0010876 573 0.056
carbohydrate derivative metabolic process GO:1901135 141 0.055
spindle localization GO:0051653 51 0.054
organic substance catabolic process GO:1901575 294 0.054
regulation of macromolecule metabolic process GO:0060255 421 0.054
Yeast
phosphate containing compound metabolic process GO:0006796 232 0.054
purine ribonucleotide metabolic process GO:0009150 95 0.054
organic cyclic compound catabolic process GO:1901361 119 0.053
aging GO:0007568 812 0.052
muscle structure development GO:0061061 191 0.051
cellular protein complex assembly GO:0043623 178 0.051
germ cell development GO:0007281 351 0.051
male gamete generation GO:0048232 41 0.051
maintenance of location GO:0051235 580 0.049
programmed cell death GO:0012501 500 0.049
regulation of meiotic cell cycle GO:0051445 136 0.049
determination of adult lifespan GO:0008340 812 0.048
cellular nitrogen compound biosynthetic process GO:0044271 192 0.048
positive regulation of developmental growth GO:0048639 354 0.048
positive regulation of cellular biosynthetic process GO:0031328 109 0.048
negative regulation of macromolecule metabolic process GO:0010605 229 0.047
cell part morphogenesis GO:0032990 152 0.046
response to external stimulus GO:0009605 289 0.046
system process GO:0003008 136 0.046
regulation of cellular biosynthetic process GO:0031326 189 0.045
striated muscle cell development GO:0055002 157 0.045
spermatogenesis GO:0007283 41 0.045
positive regulation of biosynthetic process GO:0009891 109 0.043
small molecule metabolic process GO:0044281 186 0.042
regulation of developmental growth GO:0048638 389 0.042
regulation of nitrogen compound metabolic process GO:0051171 222 0.042
organonitrogen compound metabolic process GO:1901564 151 0.042
phagocytosis GO:0006909 115 0.042
nucleobase containing compound biosynthetic process GO:0034654 184 0.041
macromolecule modification GO:0043412 218 0.041
Yeast
response to chemical GO:0042221 356 0.041
Mouse
developmental growth GO:0048589 412 0.041
regulation of response to stimulus GO:0048583 243 0.040
multicellular organismal reproductive behavior GO:0033057 384 0.038
myosin filament assembly GO:0031034 138 0.038
organic cyclic compound biosynthetic process GO:1901362 195 0.038
cell maturation GO:0048469 26 0.038
single organism biosynthetic process GO:0044711 91 0.037
cellular localization GO:0051641 360 0.037
Human Yeast Mouse
signal transduction GO:0007165 317 0.037
actin filament based process GO:0030029 191 0.037
nucleotide metabolic process GO:0009117 108 0.037
regulation of signaling GO:0023051 172 0.037
heterocycle catabolic process GO:0046700 119 0.036
nucleobase containing compound catabolic process GO:0034655 114 0.035
aromatic compound catabolic process GO:0019439 116 0.035
pronuclear migration GO:0035046 51 0.035
microtubule based process GO:0007017 182 0.035
regulation of post embryonic development GO:0048580 260 0.034
ribonucleoprotein complex assembly GO:0022618 4 0.033
regulation of cell cycle process GO:0010564 145 0.033
Yeast
meiotic chromosome segregation GO:0045132 139 0.033
negative regulation of nematode larval development GO:0061064 208 0.033
negative regulation of multicellular organismal process GO:0051241 236 0.033
single organism cellular localization GO:1902580 72 0.033
Human Yeast Mouse
cellular response to organic substance GO:0071310 119 0.033
Mouse
nucleoside phosphate catabolic process GO:1901292 77 0.031
regulation of growth GO:0040008 409 0.031
regulation of cell differentiation GO:0045595 81 0.031
nucleobase containing small molecule metabolic process GO:0055086 115 0.031
aromatic compound biosynthetic process GO:0019438 192 0.031
muscle cell development GO:0055001 158 0.030
actomyosin structure organization GO:0031032 154 0.030
generation of neurons GO:0048699 235 0.030
myosin filament organization GO:0031033 138 0.030
regulation of translation GO:0006417 19 0.030
purine containing compound metabolic process GO:0072521 95 0.029
chromosome segregation GO:0007059 180 0.029
multi organism behavior GO:0051705 389 0.029
oviposition GO:0018991 364 0.028
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.028
organelle assembly GO:0070925 214 0.028
cellular response to nitrogen compound GO:1901699 24 0.028
Mouse
behavior GO:0007610 527 0.028
ribosome biogenesis GO:0042254 4 0.028
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.027
regulation of multicellular organism growth GO:0040014 373 0.027
regulation of primary metabolic process GO:0080090 292 0.027
Yeast
dna metabolic process GO:0006259 74 0.027
defense response GO:0006952 296 0.027
cellular response to dna damage stimulus GO:0006974 41 0.027
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.026
mrna catabolic process GO:0006402 16 0.026
cellular component assembly involved in morphogenesis GO:0010927 183 0.025
meiotic cell cycle GO:0051321 335 0.025
positive regulation of nucleic acid templated transcription GO:1903508 102 0.025
single organism catabolic process GO:0044712 129 0.025
tube development GO:0035295 126 0.024
neuron development GO:0048666 199 0.024
regulation of cellular component organization GO:0051128 248 0.024
Yeast
nucleus organization GO:0006997 38 0.024
cellular response to inorganic substance GO:0071241 3 0.024
cellular protein modification process GO:0006464 207 0.023
Yeast
regulation of biosynthetic process GO:0009889 189 0.023
epithelium development GO:0060429 68 0.023
heterocycle biosynthetic process GO:0018130 187 0.022
nucleoside monophosphate metabolic process GO:0009123 46 0.022
vulval development GO:0040025 333 0.022
protein modification process GO:0036211 207 0.022
Yeast
meiotic nuclear division GO:0007126 300 0.021
molting cycle GO:0042303 281 0.021
organophosphate metabolic process GO:0019637 125 0.021
myofibril assembly GO:0030239 154 0.021
cellular component movement GO:0006928 388 0.021
positive regulation of growth GO:0045927 369 0.021
multi multicellular organism process GO:0044706 390 0.021
mrna metabolic process GO:0016071 31 0.020
regulation of cellular metabolic process GO:0031323 305 0.020
Yeast
mitotic nuclear division GO:0007067 89 0.020
Yeast
positive regulation of cellular process GO:0048522 332 0.020
Mouse
cellular macromolecule localization GO:0070727 75 0.020
Human Yeast Mouse
ribonucleoside monophosphate metabolic process GO:0009161 45 0.020
intracellular signal transduction GO:0035556 96 0.020
cell morphogenesis GO:0000902 163 0.019
protein catabolic process GO:0030163 162 0.019
cellular macromolecule catabolic process GO:0044265 73 0.019
reproductive behavior GO:0019098 387 0.019
ribonucleoside metabolic process GO:0009119 98 0.019
transcription dna templated GO:0006351 168 0.019
response to inorganic substance GO:0010035 50 0.019
nucleoside phosphate metabolic process GO:0006753 108 0.019
positive regulation of multicellular organism growth GO:0040018 352 0.019
regulation of intracellular signal transduction GO:1902531 77 0.019
regulation of localization GO:0032879 194 0.019
Mouse
immune response GO:0006955 192 0.019
regulation of anatomical structure size GO:0090066 46 0.018
negative regulation of signaling GO:0023057 61 0.018
secretion GO:0046903 147 0.018
organonitrogen compound catabolic process GO:1901565 90 0.018
chromosome organization involved in meiosis GO:0070192 25 0.018
transcription from rna polymerase ii promoter GO:0006366 149 0.018
purine ribonucleoside metabolic process GO:0046128 92 0.018
ribonucleoside catabolic process GO:0042454 77 0.017
cellular response to abiotic stimulus GO:0071214 4 0.017
cell cycle switching mitotic to meiotic cell cycle GO:0051728 35 0.017
multi organism reproductive behavior GO:0044705 387 0.017
regulation of transcription dna templated GO:0006355 164 0.017
organic substance transport GO:0071702 113 0.017
Human Yeast Mouse
purine nucleoside monophosphate metabolic process GO:0009126 43 0.017
positive regulation of intracellular transport GO:0032388 2 0.017
Mouse
purine nucleotide metabolic process GO:0006163 95 0.017
rrna metabolic process GO:0016072 3 0.017
axon development GO:0061564 163 0.017
rna localization GO:0006403 3 0.017
Yeast
striated muscle myosin thick filament assembly GO:0071688 138 0.016
skeletal muscle organ development GO:0060538 3 0.016
ribose phosphate metabolic process GO:0019693 99 0.016
establishment of spindle orientation GO:0051294 34 0.016
positive regulation of multicellular organismal process GO:0051240 417 0.016
growth GO:0040007 562 0.016
cuticle development GO:0042335 100 0.016
atp metabolic process GO:0046034 42 0.016
positive regulation of developmental process GO:0051094 408 0.016
establishment or maintenance of cell polarity GO:0007163 63 0.016
regulation of signal transduction GO:0009966 135 0.016
cell surface receptor signaling pathway GO:0007166 149 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.015
regulation of nematode larval development GO:0061062 260 0.015
positive regulation of transcription dna templated GO:0045893 102 0.015
regulation of transport GO:0051049 91 0.015
Mouse
regulation of catabolic process GO:0009894 57 0.015
ribonucleoside triphosphate metabolic process GO:0009199 87 0.015
developmental maturation GO:0021700 26 0.015
regulation of rna metabolic process GO:0051252 173 0.015
response to abiotic stimulus GO:0009628 152 0.015
response to acid chemical GO:0001101 4 0.015
Mouse
nervous system development GO:0007399 253 0.015
regulation of canonical wnt signaling pathway GO:0060828 1 0.015
regulation of apoptotic signaling pathway GO:2001233 1 0.015
nuclear transcribed mrna catabolic process GO:0000956 15 0.015
regulation of rna biosynthetic process GO:2001141 165 0.015
glycosyl compound metabolic process GO:1901657 100 0.014
positive regulation of cellular catabolic process GO:0031331 35 0.014
response to oxygen levels GO:0070482 22 0.014
negative regulation of response to stimulus GO:0048585 73 0.014
regulation of meiosis GO:0040020 94 0.014
carbohydrate derivative catabolic process GO:1901136 82 0.014
innate immune response GO:0045087 190 0.014
nucleic acid templated transcription GO:0097659 169 0.014
response to wounding GO:0009611 4 0.014
regulation of nucleic acid templated transcription GO:1903506 165 0.014
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.014
positive regulation of protein metabolic process GO:0051247 45 0.014
phosphorylation GO:0016310 116 0.014
canonical wnt signaling pathway GO:0060070 3 0.014
regulation of cellular protein metabolic process GO:0032268 75 0.013
Yeast
response to external biotic stimulus GO:0043207 101 0.013
multicellular organism growth GO:0035264 385 0.013
apoptotic cell clearance GO:0043277 111 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.013
regulation of cytoplasmic transport GO:1903649 3 0.013
Mouse
cell motility GO:0048870 313 0.013
regulation of phosphate metabolic process GO:0019220 81 0.013
cellular amino acid metabolic process GO:0006520 15 0.013
regulation of cellular ketone metabolic process GO:0010565 3 0.013
positive regulation of rna biosynthetic process GO:1902680 102 0.013
response to organic substance GO:0010033 131 0.013
Mouse
proteolysis GO:0006508 61 0.013
establishment of organelle localization GO:0051656 123 0.013
regulation of nucleocytoplasmic transport GO:0046822 3 0.013
Mouse
lipid metabolic process GO:0006629 77 0.013
embryonic morphogenesis GO:0048598 152 0.013
nuclear pore organization GO:0006999 2 0.013
response to extracellular stimulus GO:0009991 38 0.013
negative regulation of post embryonic development GO:0048581 208 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 43 0.013
coenzyme metabolic process GO:0006732 9 0.012
positive regulation of hydrolase activity GO:0051345 38 0.012
meiosis i GO:0007127 19 0.012
regulation of cell cycle GO:0051726 194 0.012
Yeast
negative regulation of cellular metabolic process GO:0031324 95 0.012
cellular response to metal ion GO:0071248 3 0.012
protein localization GO:0008104 205 0.012
Human Yeast Mouse
epithelial tube morphogenesis GO:0060562 1 0.012
head development GO:0060322 1 0.012
collagen and cuticulin based cuticle development GO:0040002 99 0.012
protein oligomerization GO:0051259 4 0.012
regulation of cellular amine metabolic process GO:0033238 0 0.012
taxis GO:0042330 128 0.012
transmembrane transport GO:0055085 110 0.012
nucleoside triphosphate metabolic process GO:0009141 87 0.012
homeostatic process GO:0042592 51 0.012
negative regulation of signal transduction GO:0009968 60 0.012
regulation of locomotion GO:0040012 161 0.012
organonitrogen compound biosynthetic process GO:1901566 44 0.012
negative regulation of cell communication GO:0010648 61 0.011
organelle fission GO:0048285 363 0.011
Yeast
cell migration GO:0016477 306 0.011
protein modification by small protein conjugation or removal GO:0070647 40 0.011
Yeast
organic acid metabolic process GO:0006082 47 0.011
purine nucleoside triphosphate metabolic process GO:0009144 87 0.011
wnt signaling pathway GO:0016055 27 0.011
establishment of mitotic spindle orientation GO:0000132 28 0.011
response to dsrna GO:0043331 10 0.011
single organism signaling GO:0044700 401 0.011
cell recognition GO:0008037 85 0.011
carboxylic acid metabolic process GO:0019752 34 0.011
anterior posterior axis specification GO:0009948 17 0.011
response to nitrogen compound GO:1901698 25 0.011
Mouse
pattern specification process GO:0007389 59 0.011
organophosphate biosynthetic process GO:0090407 26 0.011
membrane organization GO:0061024 135 0.010
regulation of behavior GO:0050795 97 0.010
amine metabolic process GO:0009308 15 0.010
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.010
localization of cell GO:0051674 313 0.010
purine nucleoside metabolic process GO:0042278 92 0.010
nucleotide catabolic process GO:0009166 77 0.010
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.010
small molecule biosynthetic process GO:0044283 38 0.010
cell division GO:0051301 262 0.010
Yeast
ribonucleotide catabolic process GO:0009261 75 0.010
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.010
membrane invagination GO:0010324 98 0.010

imb-3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.042
cancer DOID:162 0 0.017
disease of cellular proliferation DOID:14566 0 0.017
immune system disease DOID:2914 0 0.014
hematopoietic system disease DOID:74 0 0.014
nervous system disease DOID:863 0 0.013