Caenorhabditis elegans

75 known processes

sfa-1 (CELE_Y116A8C.32)

Protein SFA-1

sfa-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.182
embryo development ending in birth or egg hatching GO:0009792 2992 0.130
transport GO:0006810 1093 0.122
single organism reproductive process GO:0044702 1196 0.099
establishment of localization GO:0051234 1171 0.098
determination of adult lifespan GO:0008340 812 0.094
vesicle mediated transport GO:0016192 852 0.093
post embryonic development GO:0009791 2152 0.091
aging GO:0007568 812 0.084
locomotion GO:0040011 1634 0.083
developmental process involved in reproduction GO:0003006 1165 0.082
organelle organization GO:0006996 783 0.082
receptor mediated endocytosis GO:0006898 715 0.077
multicellular organismal aging GO:0010259 812 0.076
reproductive system development GO:0061458 850 0.076
sex differentiation GO:0007548 909 0.070
multicellular organism reproduction GO:0032504 819 0.068
development of primary sexual characteristics GO:0045137 840 0.067
endocytosis GO:0006897 819 0.065
cell death GO:0008219 547 0.064
regulation of metabolic process GO:0019222 478 0.063
Mouse
macromolecule localization GO:0033036 771 0.062
regulation of biological quality GO:0065008 741 0.062
single organism transport GO:0044765 447 0.059
genitalia development GO:0048806 741 0.059
single organism localization GO:1902578 518 0.059
growth GO:0040007 562 0.059
maintenance of location GO:0051235 580 0.058
reproductive structure development GO:0048608 850 0.058
lipid storage GO:0019915 565 0.058
organ development GO:0048513 1102 0.057
hermaphrodite genitalia development GO:0040035 734 0.057
negative regulation of biological process GO:0048519 567 0.055
gene expression GO:0010467 412 0.055
multicellular organismal reproductive process GO:0048609 815 0.054
lipid localization GO:0010876 573 0.054
multi organism reproductive process GO:0044703 867 0.052
gonad development GO:0008406 840 0.052
single organism organelle organization GO:1902589 501 0.052
apoptotic process GO:0006915 478 0.051
regulation of developmental process GO:0050793 684 0.049
death GO:0016265 547 0.048
programmed cell death GO:0012501 500 0.046
regulation of growth GO:0040008 409 0.045
cell cycle GO:0007049 526 0.042
regulation of multicellular organismal process GO:0051239 726 0.042
multicellular organism growth GO:0035264 385 0.041
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.040
gamete generation GO:0007276 461 0.040
cellular localization GO:0051641 360 0.040
regulation of developmental growth GO:0048638 389 0.039
body morphogenesis GO:0010171 620 0.039
regulation of multicellular organism growth GO:0040014 373 0.038
cell cycle process GO:0022402 482 0.038
behavior GO:0007610 527 0.037
positive regulation of multicellular organism growth GO:0040018 352 0.037
positive regulation of growth GO:0045927 369 0.036
establishment of localization in cell GO:0051649 318 0.035
multi multicellular organism process GO:0044706 390 0.035
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.034
regulation of macromolecule metabolic process GO:0060255 421 0.034
protein metabolic process GO:0019538 422 0.033
nucleobase containing compound metabolic process GO:0006139 406 0.033
positive regulation of developmental process GO:0051094 408 0.033
regulation of post embryonic development GO:0048580 260 0.033
developmental growth GO:0048589 412 0.032
regulation of gene expression epigenetic GO:0040029 163 0.032
multi organism reproductive behavior GO:0044705 387 0.032
reproductive behavior GO:0019098 387 0.032
molting cycle GO:0042303 281 0.031
positive regulation of developmental growth GO:0048639 354 0.031
negative regulation of gene expression GO:0010629 217 0.031
catabolic process GO:0009056 318 0.031
signal transduction GO:0007165 317 0.031
cell development GO:0048468 696 0.031
response to wounding GO:0009611 4 0.030
germ cell development GO:0007281 351 0.030
multicellular organismal reproductive behavior GO:0033057 384 0.030
localization of cell GO:0051674 313 0.030
negative regulation of metabolic process GO:0009892 240 0.029
regulation of gene expression GO:0010468 366 0.029
vulval development GO:0040025 333 0.028
cellular component biogenesis GO:0044085 297 0.028
regulation of nematode larval development GO:0061062 260 0.028
multi organism behavior GO:0051705 389 0.028
single organism signaling GO:0044700 401 0.028
sexual reproduction GO:0019953 546 0.027
organelle assembly GO:0070925 214 0.027
cytoskeleton organization GO:0007010 339 0.027
female gamete generation GO:0007292 254 0.027
posttranscriptional regulation of gene expression GO:0010608 166 0.027
regulation of cellular metabolic process GO:0031323 305 0.027
regulation of primary metabolic process GO:0080090 292 0.027
Mouse
organic substance biosynthetic process GO:1901576 323 0.027
Mouse
cellular component movement GO:0006928 388 0.027
positive regulation of multicellular organismal process GO:0051240 417 0.026
post embryonic organ development GO:0048569 336 0.026
regulation of vulval development GO:0040028 248 0.026
gene silencing by rna GO:0031047 143 0.025
cell division GO:0051301 262 0.025
cellular protein metabolic process GO:0044267 279 0.025
cellular component assembly GO:0022607 293 0.024
oviposition GO:0018991 364 0.024
nucleic acid metabolic process GO:0090304 299 0.024
cellular biosynthetic process GO:0044249 315 0.024
posttranscriptional gene silencing GO:0016441 143 0.024
oogenesis GO:0048477 229 0.024
negative regulation of macromolecule metabolic process GO:0010605 229 0.024
posttranscriptional gene silencing by rna GO:0035194 143 0.024
organelle fission GO:0048285 363 0.023
gene silencing GO:0016458 143 0.023
positive regulation of cellular process GO:0048522 332 0.023
negative regulation of post embryonic development GO:0048581 208 0.023
cellular protein complex assembly GO:0043623 178 0.023
protein complex biogenesis GO:0070271 186 0.023
biosynthetic process GO:0009058 323 0.023
Mouse
macromolecule modification GO:0043412 218 0.023
negative regulation of nematode larval development GO:0061064 208 0.023
macromolecular complex subunit organization GO:0043933 320 0.023
regulation of organelle organization GO:0033043 164 0.022
protein localization GO:0008104 205 0.022
negative regulation of vulval development GO:0040027 206 0.022
rna interference GO:0016246 137 0.022
regulation of cytoplasmic transport GO:1903649 3 0.022
response to abiotic stimulus GO:0009628 152 0.022
response to chemical GO:0042221 356 0.022
cell migration GO:0016477 306 0.022
organic substance catabolic process GO:1901575 294 0.022
macromolecular complex assembly GO:0065003 193 0.021
small molecule metabolic process GO:0044281 186 0.021
regulation of multicellular organismal development GO:2000026 317 0.021
head development GO:0060322 1 0.021
response to external stimulus GO:0009605 289 0.021
cell motility GO:0048870 313 0.021
membrane organization GO:0061024 135 0.021
striated muscle cell differentiation GO:0051146 158 0.020
meiotic cell cycle GO:0051321 335 0.020
muscle tissue development GO:0060537 1 0.020
cellular component assembly involved in morphogenesis GO:0010927 183 0.020
organelle localization GO:0051640 127 0.020
negative regulation of multicellular organismal process GO:0051241 236 0.020
cellular component morphogenesis GO:0032989 318 0.019
rna metabolic process GO:0016070 228 0.019
negative regulation of cellular process GO:0048523 239 0.019
cellular macromolecular complex assembly GO:0034622 184 0.019
macromolecule catabolic process GO:0009057 202 0.019
cellular catabolic process GO:0044248 199 0.019
macromolecule biosynthetic process GO:0009059 250 0.019
muscle structure development GO:0061061 191 0.019
anatomical structure formation involved in morphogenesis GO:0048646 250 0.019
cellular response to stress GO:0033554 162 0.019
protein complex assembly GO:0006461 186 0.019
neuron differentiation GO:0030182 217 0.019
regulation of cellular component organization GO:0051128 248 0.018
signaling GO:0023052 401 0.018
regulation of lipid metabolic process GO:0019216 4 0.018
Mouse
regulation of biosynthetic process GO:0009889 189 0.018
Mouse
organonitrogen compound metabolic process GO:1901564 151 0.018
regulation of cellular ketone metabolic process GO:0010565 3 0.018
sensory organ morphogenesis GO:0090596 2 0.018
generation of neurons GO:0048699 235 0.018
secretion GO:0046903 147 0.018
cellular macromolecule biosynthetic process GO:0034645 247 0.018
rna biosynthetic process GO:0032774 169 0.017
negative regulation of developmental process GO:0051093 227 0.017
striated muscle cell development GO:0055002 157 0.017
regulation of nitrogen compound metabolic process GO:0051171 222 0.017
axon development GO:0061564 163 0.017
system process GO:0003008 136 0.017
positive regulation of metabolic process GO:0009893 187 0.017
regulation of cell cycle GO:0051726 194 0.017
regulation of localization GO:0032879 194 0.017
muscle cell development GO:0055001 158 0.017
protein modification process GO:0036211 207 0.017
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.017
muscle cell differentiation GO:0042692 171 0.017
skeletal muscle organ development GO:0060538 3 0.017
protein complex subunit organization GO:0071822 280 0.017
inductive cell migration GO:0040039 145 0.016
protein catabolic process GO:0030163 162 0.016
meiotic nuclear division GO:0007126 300 0.016
epithelial tube morphogenesis GO:0060562 1 0.016
neuromuscular junction development GO:0007528 2 0.016
response to organic substance GO:0010033 131 0.016
cellular nitrogen compound catabolic process GO:0044270 119 0.016
actin filament based process GO:0030029 191 0.016
regulation of response to stimulus GO:0048583 243 0.016
regulation of apoptotic signaling pathway GO:2001233 1 0.016
actin cytoskeleton organization GO:0030036 184 0.016
defense response GO:0006952 296 0.016
cellular response to abiotic stimulus GO:0071214 4 0.016
oxoacid metabolic process GO:0043436 47 0.016
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.016
cellular protein modification process GO:0006464 207 0.016
rna localization GO:0006403 3 0.015
carbohydrate derivative metabolic process GO:1901135 141 0.015
nucleic acid templated transcription GO:0097659 169 0.015
regeneration GO:0031099 4 0.015
ribonucleoprotein complex assembly GO:0022618 4 0.015
response to topologically incorrect protein GO:0035966 82 0.015
positive regulation of macromolecule metabolic process GO:0010604 149 0.015
regulation of nuclear division GO:0051783 115 0.015
regulation of cell cycle process GO:0010564 145 0.015
carboxylic acid metabolic process GO:0019752 34 0.015
chromosome segregation GO:0007059 180 0.015
organic acid metabolic process GO:0006082 47 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
heterocycle biosynthetic process GO:0018130 187 0.015
positive regulation of cell migration GO:0030335 3 0.015
transcription dna templated GO:0006351 168 0.015
regulation of cell division GO:0051302 142 0.014
regulation of cellular amine metabolic process GO:0033238 0 0.014
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.014
cell type specific apoptotic process GO:0097285 4 0.014
phosphorus metabolic process GO:0006793 232 0.014
single organism catabolic process GO:0044712 129 0.014
regulation of nucleocytoplasmic transport GO:0046822 3 0.014
regulation of nucleic acid templated transcription GO:1903506 165 0.014
myosin filament organization GO:0031033 138 0.014
phosphate containing compound metabolic process GO:0006796 232 0.014
microtubule based process GO:0007017 182 0.014
negative regulation of gene expression epigenetic GO:0045814 2 0.014
cell projection organization GO:0030030 231 0.014
nervous system development GO:0007399 253 0.014
regulation of cellular biosynthetic process GO:0031326 189 0.014
aromatic compound biosynthetic process GO:0019438 192 0.013
nucleobase containing compound biosynthetic process GO:0034654 184 0.013
organic cyclic compound biosynthetic process GO:1901362 195 0.013
Mouse
regulation of signaling GO:0023051 172 0.013
regulation of meiotic cell cycle GO:0051445 136 0.013
phagocytosis GO:0006909 115 0.013
actomyosin structure organization GO:0031032 154 0.013
organic substance transport GO:0071702 113 0.013
regulation of cell communication GO:0010646 176 0.013
striated muscle myosin thick filament assembly GO:0071688 138 0.013
apoptotic cell clearance GO:0043277 111 0.013
ribose phosphate metabolic process GO:0019693 99 0.013
cellular ketone metabolic process GO:0042180 14 0.013
regulation of transcription dna templated GO:0006355 164 0.013
glycosyl compound metabolic process GO:1901657 100 0.013
cuticle development GO:0042335 100 0.013
myosin filament assembly GO:0031034 138 0.013
cellular response to topologically incorrect protein GO:0035967 76 0.013
regulation of cell proliferation GO:0042127 105 0.013
organic cyclic compound catabolic process GO:1901361 119 0.013
regulation of synapse assembly GO:0051963 2 0.013
myofibril assembly GO:0030239 154 0.013
adult behavior GO:0030534 3 0.013
response to temperature stimulus GO:0009266 66 0.013
carbohydrate derivative catabolic process GO:1901136 82 0.012
transcription from rna polymerase ii promoter GO:0006366 149 0.012
positive regulation of neurogenesis GO:0050769 4 0.012
cellular amino acid metabolic process GO:0006520 15 0.012
cellular nitrogen compound biosynthetic process GO:0044271 192 0.012
single organism intracellular transport GO:1902582 70 0.012
canonical wnt signaling pathway GO:0060070 3 0.012
cellular amine metabolic process GO:0044106 15 0.012
regulation of locomotion GO:0040012 161 0.012
positive regulation of intracellular transport GO:0032388 2 0.012
heterocycle catabolic process GO:0046700 119 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.012
endoplasmic reticulum unfolded protein response GO:0030968 66 0.012
cellular response to unfolded protein GO:0034620 71 0.012
negative regulation of neurogenesis GO:0050768 4 0.012
regulation of striated muscle contraction GO:0006942 4 0.012
intracellular signal transduction GO:0035556 96 0.012
rho protein signal transduction GO:0007266 2 0.012
intracellular transport GO:0046907 77 0.012
collagen and cuticulin based cuticle development GO:0040002 99 0.012
cytokinesis GO:0000910 80 0.012
ribonucleotide metabolic process GO:0009259 99 0.012
regulation of signal transduction GO:0009966 135 0.012
positive regulation of cell projection organization GO:0031346 4 0.012
organophosphate metabolic process GO:0019637 125 0.012
membrane invagination GO:0010324 98 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.012
response to unfolded protein GO:0006986 71 0.012
nucleobase containing small molecule metabolic process GO:0055086 115 0.012
synaptic growth at neuromuscular junction GO:0051124 1 0.012
aromatic compound catabolic process GO:0019439 116 0.011
positive regulation of neuron differentiation GO:0045666 4 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.011
nitrogen compound transport GO:0071705 49 0.011
engulfment of apoptotic cell GO:0043652 94 0.011
memory GO:0007613 3 0.011
regulation of protein targeting GO:1903533 3 0.011
phagocytosis engulfment GO:0006911 98 0.011
neurogenesis GO:0022008 236 0.011
axonal fasciculation GO:0007413 79 0.011
ribonucleoside metabolic process GO:0009119 98 0.011
cellular protein localization GO:0034613 75 0.011
amine metabolic process GO:0009308 15 0.011
positive regulation of vulval development GO:0040026 52 0.011
neuron recognition GO:0008038 83 0.011
muscle fiber development GO:0048747 2 0.011
mitotic cell cycle process GO:1903047 194 0.011
regulation of meiosis GO:0040020 94 0.011
purine nucleoside triphosphate metabolic process GO:0009144 87 0.011
protein oligomerization GO:0051259 4 0.011
nucleobase containing compound catabolic process GO:0034655 114 0.011
positive regulation of protein transport GO:0051222 4 0.011
cell proliferation GO:0008283 116 0.011
cellular response to chemical stimulus GO:0070887 129 0.011
response to endoplasmic reticulum stress GO:0034976 71 0.011
cellular response to organic substance GO:0071310 119 0.011
nucleotide metabolic process GO:0009117 108 0.011
embryonic morphogenesis GO:0048598 152 0.011
negative regulation of cellular metabolic process GO:0031324 95 0.011
secretion by cell GO:0032940 138 0.011
response to acid chemical GO:0001101 4 0.011
ribosome biogenesis GO:0042254 4 0.011
cellular macromolecule localization GO:0070727 75 0.010
single organism cellular localization GO:1902580 72 0.010
response to heat GO:0009408 50 0.010
regulation of cell projection assembly GO:0060491 3 0.010
regulation of rna metabolic process GO:0051252 173 0.010
nucleoside triphosphate metabolic process GO:0009141 87 0.010
purine nucleoside catabolic process GO:0006152 75 0.010
cell morphogenesis GO:0000902 163 0.010
cell projection morphogenesis GO:0048858 148 0.010
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.010
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.010
cell part morphogenesis GO:0032990 152 0.010
adult locomotory behavior GO:0008344 1 0.010
ras protein signal transduction GO:0007265 31 0.010
oocyte axis specification GO:0007309 2 0.010
establishment of protein localization to membrane GO:0090150 3 0.010
ribonucleoside triphosphate metabolic process GO:0009199 87 0.010
chemotaxis GO:0006935 120 0.010

sfa-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
nervous system disease DOID:863 0 0.014
disease of cellular proliferation DOID:14566 0 0.012
organ system cancer DOID:0050686 0 0.012
cancer DOID:162 0 0.012