Caenorhabditis elegans

15 known processes

pdi-1 (CELE_C14B1.1)

Protein PDI-1

pdi-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
fertilization GO:0009566 63 0.894
post embryonic development GO:0009791 2152 0.836
Worm
embryo development ending in birth or egg hatching GO:0009792 2992 0.759
Worm
single fertilization GO:0007338 61 0.677
embryo development GO:0009790 3052 0.561
Worm
establishment of localization GO:0051234 1171 0.424
establishment of localization in cell GO:0051649 318 0.399
protein localization to endoplasmic reticulum GO:0070972 2 0.380
vesicle mediated transport GO:0016192 852 0.337
transport GO:0006810 1093 0.292
multi organism reproductive process GO:0044703 867 0.279
cellular localization GO:0051641 360 0.236
microtubule based process GO:0007017 182 0.223
cell death GO:0008219 547 0.217
organ development GO:0048513 1102 0.212
single organism reproductive process GO:0044702 1196 0.195
single organism localization GO:1902578 518 0.192
establishment of protein localization to membrane GO:0090150 3 0.184
aging GO:0007568 812 0.183
multicellular organismal reproductive behavior GO:0033057 384 0.178
locomotion GO:0040011 1634 0.165
Worm
receptor mediated endocytosis GO:0006898 715 0.165
programmed cell death GO:0012501 500 0.165
growth GO:0040007 562 0.161
multicellular organism reproduction GO:0032504 819 0.161
cell migration GO:0016477 306 0.157
meiotic nuclear division GO:0007126 300 0.149
cell cycle GO:0007049 526 0.149
death GO:0016265 547 0.148
negative regulation of biological process GO:0048519 567 0.146
body morphogenesis GO:0010171 620 0.144
Worm
genitalia development GO:0048806 741 0.139
regulation of locomotion GO:0040012 161 0.136
endocytosis GO:0006897 819 0.136
developmental process involved in reproduction GO:0003006 1165 0.135
developmental growth GO:0048589 412 0.130
regulation of developmental process GO:0050793 684 0.122
regulation of growth GO:0040008 409 0.115
cellular response to topologically incorrect protein GO:0035967 76 0.112
Worm
cell motility GO:0048870 313 0.111
positive regulation of multicellular organismal process GO:0051240 417 0.109
apoptotic process GO:0006915 478 0.109
meiotic cell cycle process GO:1903046 170 0.105
response to endoplasmic reticulum stress GO:0034976 71 0.101
Worm
meiotic cell cycle GO:0051321 335 0.098
macromolecule localization GO:0033036 771 0.095
single organism intracellular transport GO:1902582 70 0.095
protein metabolic process GO:0019538 422 0.094
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.094
gonad development GO:0008406 840 0.092
positive regulation of developmental process GO:0051094 408 0.092
regulation of biological quality GO:0065008 741 0.091
mitotic nuclear division GO:0007067 89 0.091
development of primary sexual characteristics GO:0045137 840 0.089
oviposition GO:0018991 364 0.088
reproductive system development GO:0061458 850 0.088
single organism transport GO:0044765 447 0.087
secretion GO:0046903 147 0.086
molting cycle GO:0042303 281 0.086
determination of adult lifespan GO:0008340 812 0.086
multicellular organismal reproductive process GO:0048609 815 0.085
localization of cell GO:0051674 313 0.085
lipid localization GO:0010876 573 0.080
regulation of multicellular organismal process GO:0051239 726 0.079
positive regulation of growth GO:0045927 369 0.078
response to external stimulus GO:0009605 289 0.077
protein folding GO:0006457 7 0.076
positive regulation of multicellular organism growth GO:0040018 352 0.075
er nucleus signaling pathway GO:0006984 66 0.073
Worm
sexual reproduction GO:0019953 546 0.073
cellular protein metabolic process GO:0044267 279 0.072
positive regulation of developmental growth GO:0048639 354 0.072
maintenance of location GO:0051235 580 0.072
digestive system development GO:0055123 122 0.072
cell cycle process GO:0022402 482 0.070
behavior GO:0007610 527 0.068
secretion by cell GO:0032940 138 0.066
reproductive structure development GO:0048608 850 0.065
cell development GO:0048468 696 0.064
nervous system development GO:0007399 253 0.063
pronuclear migration GO:0035046 51 0.063
lipid storage GO:0019915 565 0.061
sensory organ morphogenesis GO:0090596 2 0.060
cell division GO:0051301 262 0.060
mitotic spindle organization GO:0007052 81 0.059
cell cell signaling GO:0007267 118 0.059
multi organism reproductive behavior GO:0044705 387 0.058
multicellular organismal aging GO:0010259 812 0.058
multicellular organism growth GO:0035264 385 0.058
head development GO:0060322 1 0.057
cellular component movement GO:0006928 388 0.055
cytoskeleton organization GO:0007010 339 0.055
regulation of metabolic process GO:0019222 478 0.054
organonitrogen compound metabolic process GO:1901564 151 0.054
Worm
protein localization GO:0008104 205 0.053
organelle organization GO:0006996 783 0.053
reproductive behavior GO:0019098 387 0.052
membrane organization GO:0061024 135 0.052
oxoacid metabolic process GO:0043436 47 0.052
Worm
organelle fission GO:0048285 363 0.050
multi organism behavior GO:0051705 389 0.050
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.049
protein complex subunit organization GO:0071822 280 0.048
regulation of localization GO:0032879 194 0.045
regulation of developmental growth GO:0048638 389 0.045
hermaphrodite genitalia development GO:0040035 734 0.041
signaling GO:0023052 401 0.040
Worm
regulation of multicellular organism growth GO:0040014 373 0.040
macromolecular complex subunit organization GO:0043933 320 0.039
dauer larval development GO:0040024 92 0.039
multi multicellular organism process GO:0044706 390 0.037
catabolic process GO:0009056 318 0.035
posttranscriptional regulation of gene expression GO:0010608 166 0.035
cellular protein localization GO:0034613 75 0.035
single organism signaling GO:0044700 401 0.034
Worm
mitotic cell cycle process GO:1903047 194 0.033
sex differentiation GO:0007548 909 0.033
regulation of cellular component organization GO:0051128 248 0.031
single organism membrane organization GO:0044802 35 0.031
intracellular transport GO:0046907 77 0.031
digestive tract development GO:0048565 122 0.031
germ cell development GO:0007281 351 0.030
single organism cellular localization GO:1902580 72 0.030
carbohydrate derivative metabolic process GO:1901135 141 0.029
cellular component biogenesis GO:0044085 297 0.028
macromolecule biosynthetic process GO:0009059 250 0.028
response to biotic stimulus GO:0009607 101 0.028
protein modification process GO:0036211 207 0.028
regulation of multicellular organismal development GO:2000026 317 0.028
intracellular protein transmembrane transport GO:0065002 4 0.027
chromosome segregation GO:0007059 180 0.027
taxis GO:0042330 128 0.027
neurogenesis GO:0022008 236 0.027
regulation of apoptotic signaling pathway GO:2001233 1 0.026
negative regulation of vulval development GO:0040027 206 0.025
protein catabolic process GO:0030163 162 0.025
protein transmembrane transport GO:0071806 4 0.025
negative regulation of nematode larval development GO:0061064 208 0.024
inductive cell migration GO:0040039 145 0.024
muscle tissue development GO:0060537 1 0.024
cellular catabolic process GO:0044248 199 0.023
immune response GO:0006955 192 0.023
response to other organism GO:0051707 101 0.023
chemotaxis GO:0006935 120 0.023
cellular macromolecule biosynthetic process GO:0034645 247 0.023
protein targeting to membrane GO:0006612 1 0.022
meiotic cytokinesis GO:0033206 15 0.022
regulation of cell motility GO:2000145 57 0.022
rna metabolic process GO:0016070 228 0.022
cellular component assembly GO:0022607 293 0.021
small molecule metabolic process GO:0044281 186 0.021
Worm
establishment of protein localization GO:0045184 50 0.021
response to unfolded protein GO:0006986 71 0.021
Worm
ribonucleoprotein complex assembly GO:0022618 4 0.021
cellular response to unfolded protein GO:0034620 71 0.021
Worm
organic substance transport GO:0071702 113 0.020
posttranscriptional gene silencing GO:0016441 143 0.020
regulation of cellular component movement GO:0051270 62 0.020
negative regulation of multicellular organismal process GO:0051241 236 0.020
regulation of response to stimulus GO:0048583 243 0.020
response to external biotic stimulus GO:0043207 101 0.020
carboxylic acid metabolic process GO:0019752 34 0.019
Worm
digestive tract morphogenesis GO:0048546 76 0.019
cell surface receptor signaling pathway GO:0007166 149 0.019
positive regulation of cell migration GO:0030335 3 0.019
cellular amino acid metabolic process GO:0006520 15 0.019
Worm
regulation of cell migration GO:0030334 55 0.018
organic substance catabolic process GO:1901575 294 0.018
embryonic morphogenesis GO:0048598 152 0.018
macromolecule catabolic process GO:0009057 202 0.018
negative regulation of macromolecule metabolic process GO:0010605 229 0.018
negative regulation of gene expression GO:0010629 217 0.018
protein transport GO:0015031 45 0.017
rna interference GO:0016246 137 0.017
phagocytosis GO:0006909 115 0.017
negative regulation of metabolic process GO:0009892 240 0.017
adult behavior GO:0030534 3 0.017
protein localization to organelle GO:0033365 37 0.017
macromolecular complex assembly GO:0065003 193 0.017
negative regulation of developmental process GO:0051093 227 0.017
cellular biosynthetic process GO:0044249 315 0.017
organ morphogenesis GO:0009887 67 0.017
single organism organelle organization GO:1902589 501 0.017
post embryonic organ development GO:0048569 336 0.017
single organism catabolic process GO:0044712 129 0.016
phosphate containing compound metabolic process GO:0006796 232 0.016
cuticle development GO:0042335 100 0.016
oxidation reduction process GO:0055114 59 0.016
Worm
vulval development GO:0040025 333 0.016
pigmentation GO:0043473 2 0.016
regulation of cellular metabolic process GO:0031323 305 0.016
meiotic chromosome segregation GO:0045132 139 0.015
polar body extrusion after meiotic divisions GO:0040038 14 0.015
posttranscriptional gene silencing by rna GO:0035194 143 0.015
regulation of vulval development GO:0040028 248 0.015
regulation of gene expression GO:0010468 366 0.015
establishment of organelle localization GO:0051656 123 0.015
macromolecule modification GO:0043412 218 0.015
tube morphogenesis GO:0035239 79 0.015
response to abiotic stimulus GO:0009628 152 0.014
nucleus localization GO:0051647 55 0.014
defense response GO:0006952 296 0.014
cellular protein complex assembly GO:0043623 178 0.014
regulation of apoptotic process GO:0042981 36 0.014
regulation of primary metabolic process GO:0080090 292 0.014
cellular component morphogenesis GO:0032989 318 0.014
adult locomotory behavior GO:0008344 1 0.013
organelle assembly GO:0070925 214 0.013
regulation of programmed cell death GO:0043067 50 0.013
aromatic compound biosynthetic process GO:0019438 192 0.013
regulation of biosynthetic process GO:0009889 189 0.013
cellular response to chemical stimulus GO:0070887 129 0.013
Worm
protein complex assembly GO:0006461 186 0.013
rna catabolic process GO:0006401 21 0.013
establishment of nucleus localization GO:0040023 55 0.013
regulation of meiotic cell cycle GO:0051445 136 0.013
cellular macromolecule catabolic process GO:0044265 73 0.013
oogenesis GO:0048477 229 0.013
negative regulation of response to stimulus GO:0048585 73 0.012
regulation of nematode larval development GO:0061062 260 0.012
cell recognition GO:0008037 85 0.012
carbohydrate metabolic process GO:0005975 34 0.012
regulation of cellular ketone metabolic process GO:0010565 3 0.012
negative regulation of cellular process GO:0048523 239 0.012
nucleobase containing compound metabolic process GO:0006139 406 0.012
gamete generation GO:0007276 461 0.012
negative regulation of post embryonic development GO:0048581 208 0.012
regulation of organelle organization GO:0033043 164 0.012
negative regulation of cell communication GO:0010648 61 0.011
macromolecular complex disassembly GO:0032984 20 0.011
regulation of gene silencing GO:0060968 3 0.011
female gamete generation GO:0007292 254 0.011
response to chemical GO:0042221 356 0.011
Worm
neuromuscular junction development GO:0007528 2 0.011
skeletal muscle organ development GO:0060538 3 0.011
spindle organization GO:0007051 92 0.011
regulation of protein ubiquitination GO:0031396 3 0.011
cell morphogenesis involved in differentiation GO:0000904 112 0.011
transmembrane transport GO:0055085 110 0.011
intracellular receptor signaling pathway GO:0030522 2 0.011
regulation of cell death GO:0010941 65 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.011
nucleic acid metabolic process GO:0090304 299 0.011
epithelial tube morphogenesis GO:0060562 1 0.011
actomyosin structure organization GO:0031032 154 0.011
collagen and cuticulin based cuticle development GO:0040002 99 0.011
tube development GO:0035295 126 0.010
purine containing compound metabolic process GO:0072521 95 0.010
oocyte axis specification GO:0007309 2 0.010
regulation of cellular biosynthetic process GO:0031326 189 0.010
cytokinesis GO:0000910 80 0.010
neuron differentiation GO:0030182 217 0.010
positive regulation of cellular process GO:0048522 332 0.010
regulation of cell division GO:0051302 142 0.010
muscle cell differentiation GO:0042692 171 0.010

pdi-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.034
disease of cellular proliferation DOID:14566 0 0.010