Caenorhabditis elegans

13 known processes

pdhb-1 (CELE_C04C3.3)

Protein PDHB-1

pdhb-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.915
embryo development ending in birth or egg hatching GO:0009792 2992 0.914
post embryonic development GO:0009791 2152 0.885
establishment of localization GO:0051234 1171 0.655
gamete generation GO:0007276 461 0.577
single organism transport GO:0044765 447 0.499
transport GO:0006810 1093 0.493
single organism localization GO:1902578 518 0.452
multicellular organism reproduction GO:0032504 819 0.444
phosphate containing compound metabolic process GO:0006796 232 0.441
phosphorus metabolic process GO:0006793 232 0.426
Human
multicellular organismal reproductive process GO:0048609 815 0.422
vesicle mediated transport GO:0016192 852 0.408
nucleobase containing small molecule metabolic process GO:0055086 115 0.406
ribonucleoside triphosphate metabolic process GO:0009199 87 0.362
purine nucleotide metabolic process GO:0006163 95 0.355
endocytosis GO:0006897 819 0.341
ribose phosphate metabolic process GO:0019693 99 0.293
organelle organization GO:0006996 783 0.293
carbohydrate derivative metabolic process GO:1901135 141 0.292
organelle assembly GO:0070925 214 0.291
purine containing compound metabolic process GO:0072521 95 0.284
sexual reproduction GO:0019953 546 0.282
single organism organelle organization GO:1902589 501 0.263
positive regulation of cellular process GO:0048522 332 0.254
nucleobase containing compound metabolic process GO:0006139 406 0.245
organ development GO:0048513 1102 0.241
purine ribonucleotide metabolic process GO:0009150 95 0.238
multicellular organismal aging GO:0010259 812 0.236
multi organism reproductive process GO:0044703 867 0.226
organophosphate metabolic process GO:0019637 125 0.219
atp metabolic process GO:0046034 42 0.218
germ cell development GO:0007281 351 0.211
organonitrogen compound metabolic process GO:1901564 151 0.209
single organism signaling GO:0044700 401 0.204
aging GO:0007568 812 0.199
nucleotide metabolic process GO:0009117 108 0.195
nucleoside triphosphate metabolic process GO:0009141 87 0.190
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.188
locomotion GO:0040011 1634 0.185
catabolic process GO:0009056 318 0.180
nucleoside phosphate metabolic process GO:0006753 108 0.177
purine nucleoside triphosphate metabolic process GO:0009144 87 0.172
fertilization GO:0009566 63 0.164
purine nucleoside metabolic process GO:0042278 92 0.157
developmental process involved in reproduction GO:0003006 1165 0.150
receptor mediated endocytosis GO:0006898 715 0.150
small molecule metabolic process GO:0044281 186 0.146
Human
ribonucleotide metabolic process GO:0009259 99 0.145
purine ribonucleoside metabolic process GO:0046128 92 0.142
regulation of biological quality GO:0065008 741 0.140
hermaphrodite genitalia development GO:0040035 734 0.133
programmed cell death GO:0012501 500 0.131
cellular localization GO:0051641 360 0.128
ribonucleoside monophosphate metabolic process GO:0009161 45 0.123
regulation of primary metabolic process GO:0080090 292 0.123
cell death GO:0008219 547 0.123
body morphogenesis GO:0010171 620 0.122
nucleoside monophosphate metabolic process GO:0009123 46 0.121
purine nucleoside monophosphate metabolic process GO:0009126 43 0.121
protein complex subunit organization GO:0071822 280 0.120
single organism reproductive process GO:0044702 1196 0.119
determination of adult lifespan GO:0008340 812 0.119
establishment of localization in cell GO:0051649 318 0.117
phagocytosis GO:0006909 115 0.113
multi organism behavior GO:0051705 389 0.105
macromolecule localization GO:0033036 771 0.103
signal transduction GO:0007165 317 0.101
carbohydrate derivative catabolic process GO:1901136 82 0.101
apoptotic process GO:0006915 478 0.101
multicellular organismal reproductive behavior GO:0033057 384 0.100
gonad development GO:0008406 840 0.097
female gamete generation GO:0007292 254 0.096
purine ribonucleoside monophosphate metabolic process GO:0009167 43 0.096
ribonucleoside metabolic process GO:0009119 98 0.096
single organism catabolic process GO:0044712 129 0.095
positive regulation of cellular metabolic process GO:0031325 178 0.094
glycosyl compound metabolic process GO:1901657 100 0.094
death GO:0016265 547 0.094
organic substance catabolic process GO:1901575 294 0.094
head development GO:0060322 1 0.091
nucleoside metabolic process GO:0009116 99 0.091
cytoskeleton organization GO:0007010 339 0.090
cellular component biogenesis GO:0044085 297 0.086
cellular respiration GO:0045333 9 0.085
Human
regulation of multicellular organism growth GO:0040014 373 0.081
oogenesis GO:0048477 229 0.081
organic substance biosynthetic process GO:1901576 323 0.081
Human
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.080
regulation of signaling GO:0023051 172 0.079
oviposition GO:0018991 364 0.079
cellular component assembly involved in morphogenesis GO:0010927 183 0.078
secretion by cell GO:0032940 138 0.076
cellular component morphogenesis GO:0032989 318 0.076
positive regulation of metabolic process GO:0009893 187 0.075
negative regulation of cellular process GO:0048523 239 0.075
negative regulation of biological process GO:0048519 567 0.073
response to organic substance GO:0010033 131 0.071
growth GO:0040007 562 0.069
establishment of organelle localization GO:0051656 123 0.068
genitalia development GO:0048806 741 0.068
signaling GO:0023052 401 0.068
regulation of growth GO:0040008 409 0.068
macromolecular complex subunit organization GO:0043933 320 0.068
regulation of multicellular organismal process GO:0051239 726 0.067
regulation of developmental growth GO:0048638 389 0.067
organelle localization GO:0051640 127 0.066
actomyosin structure organization GO:0031032 154 0.066
positive regulation of multicellular organismal process GO:0051240 417 0.064
reproductive system development GO:0061458 850 0.064
cell development GO:0048468 696 0.064
developmental growth GO:0048589 412 0.063
behavior GO:0007610 527 0.062
generation of precursor metabolites and energy GO:0006091 18 0.062
Human
cation transport GO:0006812 78 0.062
development of primary sexual characteristics GO:0045137 840 0.062
transmembrane transport GO:0055085 110 0.060
lipid localization GO:0010876 573 0.059
response to chemical GO:0042221 356 0.059
regulation of gene expression GO:0010468 366 0.059
lipid storage GO:0019915 565 0.058
multicellular organism growth GO:0035264 385 0.058
positive regulation of growth GO:0045927 369 0.057
glycosyl compound catabolic process GO:1901658 79 0.057
protein metabolic process GO:0019538 422 0.057
cellular response to organic substance GO:0071310 119 0.056
maintenance of location GO:0051235 580 0.056
apoptotic cell clearance GO:0043277 111 0.056
aromatic compound biosynthetic process GO:0019438 192 0.056
multi multicellular organism process GO:0044706 390 0.055
nucleobase containing compound biosynthetic process GO:0034654 184 0.053
regulation of cellular metabolic process GO:0031323 305 0.053
positive regulation of developmental process GO:0051094 408 0.053
muscle cell differentiation GO:0042692 171 0.053
secretion GO:0046903 147 0.053
striated muscle cell development GO:0055002 157 0.051
striated muscle cell differentiation GO:0051146 158 0.051
regulation of response to stimulus GO:0048583 243 0.051
regulation of metabolic process GO:0019222 478 0.050
spermatogenesis GO:0007283 41 0.050
cellular response to stress GO:0033554 162 0.050
ribonucleoside triphosphate catabolic process GO:0009203 72 0.050
actin cytoskeleton organization GO:0030036 184 0.049
protein modification process GO:0036211 207 0.049
cellular component assembly GO:0022607 293 0.049
purine containing compound catabolic process GO:0072523 75 0.049
regulation of cytoplasmic transport GO:1903649 3 0.049
regulation of cell communication GO:0010646 176 0.049
macromolecular complex assembly GO:0065003 193 0.048
ion transmembrane transport GO:0034220 91 0.047
reproductive structure development GO:0048608 850 0.046
oocyte construction GO:0007308 2 0.046
cell cell signaling GO:0007267 118 0.045
carbohydrate metabolic process GO:0005975 34 0.045
ribonucleotide catabolic process GO:0009261 75 0.045
muscle cell development GO:0055001 158 0.045
cellular catabolic process GO:0044248 199 0.044
anatomical structure formation involved in morphogenesis GO:0048646 250 0.044
cellular response to chemical stimulus GO:0070887 129 0.043
nervous system development GO:0007399 253 0.043
response to wounding GO:0009611 4 0.043
cellular protein metabolic process GO:0044267 279 0.042
membrane organization GO:0061024 135 0.042
single fertilization GO:0007338 61 0.040
regulation of developmental process GO:0050793 684 0.040
mitochondrion organization GO:0007005 20 0.040
oxidation reduction process GO:0055114 59 0.039
Human Zebrafish
biosynthetic process GO:0009058 323 0.039
Human
male gamete generation GO:0048232 41 0.038
cellular biosynthetic process GO:0044249 315 0.038
Human
regulation of macromolecule metabolic process GO:0060255 421 0.037
regulation of signal transduction GO:0009966 135 0.036
positive regulation of developmental growth GO:0048639 354 0.036
reproductive behavior GO:0019098 387 0.036
positive regulation of multicellular organism growth GO:0040018 352 0.035
myosin filament assembly GO:0031034 138 0.034
regulation of reproductive process GO:2000241 66 0.034
nucleic acid metabolic process GO:0090304 299 0.033
heterocycle catabolic process GO:0046700 119 0.033
purine nucleoside catabolic process GO:0006152 75 0.032
protein complex biogenesis GO:0070271 186 0.032
regulation of cellular component organization GO:0051128 248 0.032
carboxylic acid metabolic process GO:0019752 34 0.031
Human
purine nucleoside monophosphate biosynthetic process GO:0009127 4 0.031
purine nucleotide catabolic process GO:0006195 75 0.031
regulation of multi organism process GO:0043900 69 0.031
system process GO:0003008 136 0.031
myosin filament organization GO:0031033 138 0.031
organonitrogen compound catabolic process GO:1901565 90 0.030
multi organism reproductive behavior GO:0044705 387 0.030
regulation of cellular biosynthetic process GO:0031326 189 0.030
cellular protein complex assembly GO:0043623 178 0.030
regulation of catabolic process GO:0009894 57 0.030
molting cycle GO:0042303 281 0.029
myofibril assembly GO:0030239 154 0.029
purine nucleoside triphosphate catabolic process GO:0009146 72 0.029
response to external stimulus GO:0009605 289 0.029
microtubule based process GO:0007017 182 0.028
organic cyclic compound biosynthetic process GO:1901362 195 0.028
membrane invagination GO:0010324 98 0.028
cellular nitrogen compound catabolic process GO:0044270 119 0.028
meiotic cell cycle GO:0051321 335 0.027
muscle structure development GO:0061061 191 0.027
actin filament based process GO:0030029 191 0.027
regulation of cellular protein metabolic process GO:0032268 75 0.027
detection of external stimulus GO:0009581 4 0.027
aromatic compound catabolic process GO:0019439 116 0.026
inorganic cation transmembrane transport GO:0098662 46 0.026
cell part morphogenesis GO:0032990 152 0.026
cation transmembrane transport GO:0098655 59 0.025
response to endoplasmic reticulum stress GO:0034976 71 0.025
striated muscle myosin thick filament assembly GO:0071688 138 0.025
regulation of biosynthetic process GO:0009889 189 0.025
cellular nitrogen compound biosynthetic process GO:0044271 192 0.024
intracellular receptor signaling pathway GO:0030522 2 0.024
nucleoside catabolic process GO:0009164 78 0.024
nucleoside phosphate catabolic process GO:1901292 77 0.024
phagocytosis engulfment GO:0006911 98 0.024
macromolecule modification GO:0043412 218 0.024
regulation of localization GO:0032879 194 0.024
negative regulation of multicellular organismal process GO:0051241 236 0.024
engulfment of apoptotic cell GO:0043652 94 0.024
negative regulation of metabolic process GO:0009892 240 0.023
cellular macromolecule localization GO:0070727 75 0.023
regeneration GO:0031099 4 0.023
nucleoside triphosphate catabolic process GO:0009143 72 0.023
regulation of oviposition GO:0046662 43 0.022
vulval development GO:0040025 333 0.022
negative regulation of response to stimulus GO:0048585 73 0.022
ribonucleoside monophosphate biosynthetic process GO:0009156 6 0.022
organic acid metabolic process GO:0006082 47 0.022
Human
cell fate commitment GO:0045165 139 0.022
phosphorylation GO:0016310 116 0.022
ribonucleoside catabolic process GO:0042454 77 0.022
gene expression GO:0010467 412 0.021
cellular macromolecular complex assembly GO:0034622 184 0.021
er nucleus signaling pathway GO:0006984 66 0.021
oxoacid metabolic process GO:0043436 47 0.020
Human
regulation of protein metabolic process GO:0051246 81 0.020
regulation of transport GO:0051049 91 0.020
purine ribonucleoside catabolic process GO:0046130 75 0.020
sex differentiation GO:0007548 909 0.020
protein complex assembly GO:0006461 186 0.020
cell cycle process GO:0022402 482 0.020
cell cycle GO:0007049 526 0.020
organic substance transport GO:0071702 113 0.020
response to abiotic stimulus GO:0009628 152 0.020
spindle organization GO:0007051 92 0.020
calcium mediated signaling GO:0019722 3 0.019
negative regulation of vulval development GO:0040027 206 0.019
positive regulation of macromolecule metabolic process GO:0010604 149 0.019
feeding behavior GO:0007631 70 0.019
regulation of cellular localization GO:0060341 42 0.018
adenine nucleotide transport GO:0051503 2 0.018
male mating behavior GO:0060179 26 0.018
endoplasmic reticulum unfolded protein response GO:0030968 66 0.018
purine ribonucleotide catabolic process GO:0009154 75 0.018
ion transport GO:0006811 113 0.018
nucleobase containing compound catabolic process GO:0034655 114 0.017
heterocycle biosynthetic process GO:0018130 187 0.017
oxidative phosphorylation GO:0006119 11 0.017
nucleotide catabolic process GO:0009166 77 0.017
negative regulation of gene expression GO:0010629 217 0.017
intracellular transport GO:0046907 77 0.017
regulation of behavior GO:0050795 97 0.017
regulation of protein stability GO:0031647 3 0.016
organophosphate catabolic process GO:0046434 81 0.016
negative regulation of cell communication GO:0010648 61 0.016
regulation of nematode larval development GO:0061062 260 0.016
protein localization GO:0008104 205 0.016
mitotic cell cycle process GO:1903047 194 0.016
eating behavior GO:0042755 59 0.015
regulation of apoptotic signaling pathway GO:2001233 1 0.015
negative regulation of signal transduction GO:0009968 60 0.015
inorganic ion transmembrane transport GO:0098660 54 0.015
cellular protein modification process GO:0006464 207 0.015
ovulation GO:0030728 33 0.015
single organism carbohydrate metabolic process GO:0044723 29 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.015
organic cyclic compound catabolic process GO:1901361 119 0.015
negative regulation of apoptotic process GO:0043066 17 0.014
cellular response to topologically incorrect protein GO:0035967 76 0.014
electron transport chain GO:0022900 9 0.014
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.014
pharyngeal pumping GO:0043050 58 0.014
negative regulation of signaling GO:0023057 61 0.014
macromolecule catabolic process GO:0009057 202 0.014
cell proliferation GO:0008283 116 0.014
regulation of nitrogen compound metabolic process GO:0051171 222 0.014
negative regulation of cellular metabolic process GO:0031324 95 0.014
apoptotic mitochondrial changes GO:0008637 2 0.013
regulation of macromolecule biosynthetic process GO:0010556 189 0.013
single organism intracellular transport GO:1902582 70 0.013
positive regulation of intracellular transport GO:0032388 2 0.013
regulation of molecular function GO:0065009 89 0.013
ribonucleoside monophosphate catabolic process GO:0009158 28 0.013
dna metabolic process GO:0006259 74 0.012
regulation of rna metabolic process GO:0051252 173 0.012
microtubule cytoskeleton organization involved in mitosis GO:1902850 12 0.012
mitotic nuclear division GO:0007067 89 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.012
organonitrogen compound biosynthetic process GO:1901566 44 0.012
regulation of cellular catabolic process GO:0031329 51 0.012
neurological system process GO:0050877 53 0.012
developmental maturation GO:0021700 26 0.012
cellular component movement GO:0006928 388 0.012
macromolecule biosynthetic process GO:0009059 250 0.012
regulation of cell proliferation GO:0042127 105 0.012
digestive system development GO:0055123 122 0.011
cellular homeostasis GO:0019725 22 0.011
cellular amino acid metabolic process GO:0006520 15 0.011
muscle tissue development GO:0060537 1 0.011
response to unfolded protein GO:0006986 71 0.011
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.011
organelle fission GO:0048285 363 0.011
intracellular signal transduction GO:0035556 96 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 28 0.011
tube morphogenesis GO:0035239 79 0.011
regulation of secretion GO:0051046 29 0.011
purine nucleoside monophosphate catabolic process GO:0009128 28 0.011
regulation of apoptotic process GO:0042981 36 0.011
atp catabolic process GO:0006200 27 0.011
cell migration GO:0016477 306 0.011
regulation of cell death GO:0010941 65 0.010
posttranscriptional regulation of gene expression GO:0010608 166 0.010
organophosphate biosynthetic process GO:0090407 26 0.010
organism emergence from protective structure GO:0071684 48 0.010
purine ribonucleoside monophosphate biosynthetic process GO:0009168 4 0.010
neurogenesis GO:0022008 236 0.010
mitochondrial electron transport nadh to ubiquinone GO:0006120 4 0.010
regulation of programmed cell death GO:0043067 50 0.010
detection of abiotic stimulus GO:0009582 4 0.010

pdhb-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.072
disease of anatomical entity DOID:7 0 0.035
cancer DOID:162 0 0.032
disease of cellular proliferation DOID:14566 0 0.032
inherited metabolic disorder DOID:655 0 0.030
organ system cancer DOID:0050686 0 0.017
nervous system disease DOID:863 0 0.013