Caenorhabditis elegans

29 known processes

syg-2 (CELE_C26G2.1)

Protein SYG-2

syg-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.591
axonogenesis GO:0007409 102 0.563
cell part morphogenesis GO:0032990 152 0.525
embryo development GO:0009790 3052 0.501
Fly
cell morphogenesis GO:0000902 163 0.484
locomotion GO:0040011 1634 0.479
taxis GO:0042330 128 0.460
embryo development ending in birth or egg hatching GO:0009792 2992 0.459
Fly
organ development GO:0048513 1102 0.423
Zebrafish Mouse Fly
axon guidance GO:0007411 82 0.411
positive regulation of cellular process GO:0048522 332 0.356
Mouse Fly
tube development GO:0035295 126 0.343
Fly
cellular component movement GO:0006928 388 0.341
axon development GO:0061564 163 0.340
head development GO:0060322 1 0.327
negative regulation of biological process GO:0048519 567 0.312
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.308
neuron development GO:0048666 199 0.306
cellular component morphogenesis GO:0032989 318 0.300
nervous system development GO:0007399 253 0.294
cell motility GO:0048870 313 0.281
regulation of macromolecule metabolic process GO:0060255 421 0.263
Fly
cell morphogenesis involved in differentiation GO:0000904 112 0.249
cell migration GO:0016477 306 0.247
neuron projection morphogenesis GO:0048812 114 0.227
regulation of transcription dna templated GO:0006355 164 0.227
positive regulation of developmental process GO:0051094 408 0.222
neuron projection development GO:0031175 187 0.222
positive regulation of multicellular organismal process GO:0051240 417 0.217
sex differentiation GO:0007548 909 0.210
rna biosynthetic process GO:0032774 169 0.209
epithelium development GO:0060429 68 0.208
Fly
regulation of primary metabolic process GO:0080090 292 0.206
Fly
body morphogenesis GO:0010171 620 0.204
regulation of metabolic process GO:0019222 478 0.203
Fly
neuron projection guidance GO:0097485 82 0.203
nucleic acid templated transcription GO:0097659 169 0.197
response to chemical GO:0042221 356 0.194
digestive tract development GO:0048565 122 0.193
cell projection morphogenesis GO:0048858 148 0.193
localization of cell GO:0051674 313 0.193
regulation of gene expression GO:0010468 366 0.189
post embryonic development GO:0009791 2152 0.188
Fly
developmental process involved in reproduction GO:0003006 1165 0.186
Fly
cellular biosynthetic process GO:0044249 315 0.172
transport GO:0006810 1093 0.171
Mouse
organelle organization GO:0006996 783 0.168
Mouse Fly
neurogenesis GO:0022008 236 0.167
organic substance biosynthetic process GO:1901576 323 0.166
regulation of rna biosynthetic process GO:2001141 165 0.165
cell projection organization GO:0030030 231 0.163
growth GO:0040007 562 0.163
neuron differentiation GO:0030182 217 0.162
cell development GO:0048468 696 0.161
macromolecule biosynthetic process GO:0009059 250 0.160
response to external stimulus GO:0009605 289 0.160
reproductive structure development GO:0048608 850 0.159
organic cyclic compound biosynthetic process GO:1901362 195 0.154
regulation of developmental process GO:0050793 684 0.152
Fly
regulation of multicellular organismal development GO:2000026 317 0.150
Fly
negative regulation of cellular process GO:0048523 239 0.148
regulation of multicellular organismal process GO:0051239 726 0.147
Mouse Fly
regulation of cellular biosynthetic process GO:0031326 189 0.147
cellular macromolecule biosynthetic process GO:0034645 247 0.143
gene expression GO:0010467 412 0.142
muscle tissue development GO:0060537 1 0.140
Zebrafish Mouse Fly
embryonic morphogenesis GO:0048598 152 0.139
chemotaxis GO:0006935 120 0.134
generation of neurons GO:0048699 235 0.134
regulation of anatomical structure size GO:0090066 46 0.133
Mouse
tissue development GO:0009888 112 0.132
Zebrafish Mouse Fly
transcription from rna polymerase ii promoter GO:0006366 149 0.131
organ morphogenesis GO:0009887 67 0.128
Fly
regulation of developmental growth GO:0048638 389 0.128
digestive system development GO:0055123 122 0.127
cytoskeleton organization GO:0007010 339 0.126
Mouse Fly
rna metabolic process GO:0016070 228 0.125
regulation of rna metabolic process GO:0051252 173 0.124
muscle organ development GO:0007517 26 0.122
Zebrafish Mouse Fly
vesicle mediated transport GO:0016192 852 0.120
regulation of nitrogen compound metabolic process GO:0051171 222 0.119
endocytosis GO:0006897 819 0.117
negative regulation of metabolic process GO:0009892 240 0.117
digestive tract morphogenesis GO:0048546 76 0.117
biosynthetic process GO:0009058 323 0.115
heterocycle biosynthetic process GO:0018130 187 0.115
receptor mediated endocytosis GO:0006898 715 0.114
skeletal muscle organ development GO:0060538 3 0.113
Zebrafish Mouse
multi organism reproductive process GO:0044703 867 0.113
Fly
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.110
regulation of nucleic acid templated transcription GO:1903506 165 0.107
regulation of macromolecule biosynthetic process GO:0010556 189 0.107
neuron recognition GO:0008038 83 0.106
positive regulation of nucleic acid templated transcription GO:1903508 102 0.106
post embryonic organ development GO:0048569 336 0.106
Fly
signal transduction GO:0007165 317 0.105
Mouse Fly
vulval development GO:0040025 333 0.105
cell surface receptor signaling pathway GO:0007166 149 0.105
Fly
cell fate commitment GO:0045165 139 0.104
nucleobase containing compound biosynthetic process GO:0034654 184 0.101
negative regulation of gene expression GO:0010629 217 0.101
gastrulation GO:0007369 58 0.100
cell death GO:0008219 547 0.100
protein localization GO:0008104 205 0.099
tissue morphogenesis GO:0048729 65 0.098
Fly
regulation of axonogenesis GO:0050770 24 0.096
regulation of cell morphogenesis involved in differentiation GO:0010769 29 0.096
nucleic acid metabolic process GO:0090304 299 0.096
transcription dna templated GO:0006351 168 0.095
aging GO:0007568 812 0.092
epithelial tube morphogenesis GO:0060562 1 0.091
macromolecule localization GO:0033036 771 0.089
development of primary sexual characteristics GO:0045137 840 0.089
signaling GO:0023052 401 0.088
protein metabolic process GO:0019538 422 0.087
Fly
skin development GO:0043588 24 0.087
aromatic compound biosynthetic process GO:0019438 192 0.087
regulation of neuron projection development GO:0010975 31 0.086
cellular nitrogen compound biosynthetic process GO:0044271 192 0.086
single organism reproductive process GO:0044702 1196 0.086
Fly
axon extension GO:0048675 37 0.085
reproductive system development GO:0061458 850 0.084
gonad development GO:0008406 840 0.082
tube morphogenesis GO:0035239 79 0.080
developmental growth GO:0048589 412 0.080
regulation of biosynthetic process GO:0009889 189 0.078
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.078
regulation of cell motility GO:2000145 57 0.078
determination of adult lifespan GO:0008340 812 0.077
establishment of localization GO:0051234 1171 0.077
Mouse
negative regulation of biosynthetic process GO:0009890 65 0.077
positive regulation of metabolic process GO:0009893 187 0.074
Fly
anatomical structure formation involved in morphogenesis GO:0048646 250 0.074
Mouse Fly
negative regulation of multicellular organismal process GO:0051241 236 0.073
positive regulation of neurogenesis GO:0050769 4 0.073
multicellular organism reproduction GO:0032504 819 0.073
Fly
positive regulation of cellular biosynthetic process GO:0031328 109 0.073
regulation of cellular component movement GO:0051270 62 0.072
single organism localization GO:1902578 518 0.072
Mouse
regulation of growth GO:0040008 409 0.071
regulation of cell morphogenesis GO:0022604 40 0.071
regulation of biological quality GO:0065008 741 0.070
Mouse
programmed cell death GO:0012501 500 0.070
multicellular organismal reproductive process GO:0048609 815 0.068
Fly
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.067
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.067
negative regulation of developmental process GO:0051093 227 0.067
positive regulation of macromolecule metabolic process GO:0010604 149 0.066
Fly
nucleobase containing compound metabolic process GO:0006139 406 0.066
extracellular matrix organization GO:0030198 6 0.065
multicellular organismal aging GO:0010259 812 0.065
regulation of nervous system development GO:0051960 41 0.065
cell recognition GO:0008037 85 0.065
positive regulation of biosynthetic process GO:0009891 109 0.063
muscle structure development GO:0061061 191 0.063
Zebrafish Mouse Fly
actin filament based process GO:0030029 191 0.062
Mouse Fly
positive regulation of cellular metabolic process GO:0031325 178 0.062
Fly
positive regulation of growth GO:0045927 369 0.059
cell cell signaling GO:0007267 118 0.059
innate immune response GO:0045087 190 0.057
regulation of multicellular organism growth GO:0040014 373 0.057
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.056
negative regulation of macromolecule metabolic process GO:0010605 229 0.055
gamete generation GO:0007276 461 0.055
Fly
positive regulation of rna metabolic process GO:0051254 103 0.055
maintenance of location GO:0051235 580 0.054
positive regulation of developmental growth GO:0048639 354 0.054
regulation of cellular component organization GO:0051128 248 0.053
Mouse
actin cytoskeleton organization GO:0030036 184 0.053
Mouse Fly
negative regulation of cellular metabolic process GO:0031324 95 0.052
epidermis development GO:0008544 24 0.051
regulation of post embryonic development GO:0048580 260 0.051
positive regulation of transcription dna templated GO:0045893 102 0.051
cellular response to stress GO:0033554 162 0.050
Mouse
lipid localization GO:0010876 573 0.050
regulation of organ morphogenesis GO:2000027 4 0.050
single organism signaling GO:0044700 401 0.049
regulation of vulval development GO:0040028 248 0.049
lipid storage GO:0019915 565 0.049
negative regulation of cellular biosynthetic process GO:0031327 65 0.048
sensory organ morphogenesis GO:0090596 2 0.048
Fly
regulation of stem cell differentiation GO:2000736 1 0.048
regulation of neuron differentiation GO:0045664 40 0.048
positive regulation of multicellular organism growth GO:0040018 352 0.048
biological adhesion GO:0022610 21 0.047
Mouse Fly
cellular response to chemical stimulus GO:0070887 129 0.046
apoptotic process GO:0006915 478 0.046
negative regulation of transcription dna templated GO:0045892 53 0.045
regulation of cellular metabolic process GO:0031323 305 0.045
Fly
regulation of extent of cell growth GO:0061387 20 0.044
death GO:0016265 547 0.043
positive regulation of cell projection organization GO:0031346 4 0.043
epithelial cell proliferation GO:0050673 1 0.043
regulation of signaling GO:0023051 172 0.042
Fly
single organism biosynthetic process GO:0044711 91 0.042
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.042
sexual reproduction GO:0019953 546 0.042
Fly
molting cycle GO:0042303 281 0.042
phosphate containing compound metabolic process GO:0006796 232 0.041
Mouse
cellular localization GO:0051641 360 0.041
extracellular structure organization GO:0043062 7 0.041
immune response GO:0006955 192 0.040
positive regulation of neuron projection development GO:0010976 4 0.040
developmental growth involved in morphogenesis GO:0060560 37 0.039
oviposition GO:0018991 364 0.039
synaptic target recognition GO:0008039 3 0.039
pattern specification process GO:0007389 59 0.038
protein complex subunit organization GO:0071822 280 0.038
Mouse
negative regulation of rna biosynthetic process GO:1902679 53 0.038
regulation of epithelial cell proliferation GO:0050678 1 0.038
regulation of organelle organization GO:0033043 164 0.037
Mouse
regulation of anatomical structure morphogenesis GO:0022603 51 0.037
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.036
positive regulation of neuron differentiation GO:0045666 4 0.036
genitalia development GO:0048806 741 0.036
regulation of cell migration GO:0030334 55 0.035
developmental cell growth GO:0048588 39 0.035
positive regulation of rna biosynthetic process GO:1902680 102 0.035
cellular protein metabolic process GO:0044267 279 0.035
Fly
response to organic substance GO:0010033 131 0.035
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.035
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.034
regulation of neurogenesis GO:0050767 40 0.034
muscle cell differentiation GO:0042692 171 0.034
Zebrafish Mouse Fly
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.034
response to topologically incorrect protein GO:0035966 82 0.034
collagen and cuticulin based cuticle development GO:0040002 99 0.034
single organism organelle organization GO:1902589 501 0.034
Mouse Fly
response to unfolded protein GO:0006986 71 0.034
neuron projection extension GO:1990138 37 0.034
secretion GO:0046903 147 0.033
Mouse
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.033
regulation of nematode larval development GO:0061062 260 0.033
positive regulation of cell differentiation GO:0045597 8 0.033
regulation of cell projection organization GO:0031344 38 0.033
protein modification process GO:0036211 207 0.032
multi organism behavior GO:0051705 389 0.032
striated muscle cell differentiation GO:0051146 158 0.032
Zebrafish Mouse Fly
cellular protein modification process GO:0006464 207 0.032
establishment of localization in cell GO:0051649 318 0.031
regulation of locomotion GO:0040012 161 0.031
macromolecular complex subunit organization GO:0043933 320 0.031
Mouse
regulation of cell development GO:0060284 49 0.030
establishment of organelle localization GO:0051656 123 0.030
macromolecule modification GO:0043412 218 0.030
cellular component biogenesis GO:0044085 297 0.030
Mouse Fly
cell division GO:0051301 262 0.030
regulation of cellular protein metabolic process GO:0032268 75 0.030
Fly
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.029
dendrite development GO:0016358 42 0.028
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.028
embryonic body morphogenesis GO:0010172 49 0.028
small molecule metabolic process GO:0044281 186 0.028
regulation of catalytic activity GO:0050790 78 0.027
Fly
nucleotide metabolic process GO:0009117 108 0.027
cellular protein complex assembly GO:0043623 178 0.027
Mouse
microtubule based process GO:0007017 182 0.027
negative regulation of nucleic acid templated transcription GO:1903507 53 0.027
response to wounding GO:0009611 4 0.027
germ cell development GO:0007281 351 0.026
Fly
cell proliferation GO:0008283 116 0.026
hermaphrodite genitalia development GO:0040035 734 0.026
negative regulation of rna metabolic process GO:0051253 53 0.026
regionalization GO:0003002 31 0.026
multicellular organismal reproductive behavior GO:0033057 384 0.026
positive regulation of gene expression GO:0010628 112 0.026
organophosphate metabolic process GO:0019637 125 0.025
neuromuscular junction development GO:0007528 2 0.025
cuticle development GO:0042335 100 0.025
regulation of cell size GO:0008361 30 0.025
organelle assembly GO:0070925 214 0.024
regulation of cell proliferation GO:0042127 105 0.024
regulation of synapse assembly GO:0051963 2 0.023
nucleobase containing small molecule metabolic process GO:0055086 115 0.023
multicellular organism growth GO:0035264 385 0.023
secretion by cell GO:0032940 138 0.023
regulation of cellular component size GO:0032535 40 0.023
Mouse
single organism transport GO:0044765 447 0.023
Mouse
cellular component assembly GO:0022607 293 0.022
Mouse Fly
negative regulation of neurogenesis GO:0050768 4 0.022
positive regulation of vulval development GO:0040026 52 0.022
macromolecule catabolic process GO:0009057 202 0.022
organelle localization GO:0051640 127 0.022
cellular response to organic substance GO:0071310 119 0.022
organic substance catabolic process GO:1901575 294 0.022
carboxylic acid metabolic process GO:0019752 34 0.021
axon extension involved in axon guidance GO:0048846 13 0.021
cell substrate adhesion GO:0031589 1 0.021
lamellipodium organization GO:0097581 2 0.021
nucleoside phosphate metabolic process GO:0006753 108 0.021
multi organism reproductive behavior GO:0044705 387 0.021
regulation of muscle cell differentiation GO:0051147 1 0.021
protein catabolic process GO:0030163 162 0.020
negative regulation of cell communication GO:0010648 61 0.020
gabaergic neuron differentiation GO:0097154 1 0.020
hormone transport GO:0009914 2 0.020
multi multicellular organism process GO:0044706 390 0.020
muscle organ morphogenesis GO:0048644 4 0.020
cell cycle GO:0007049 526 0.020
response to abiotic stimulus GO:0009628 152 0.019
ribose phosphate metabolic process GO:0019693 99 0.019
cell cycle process GO:0022402 482 0.019
negative regulation of cell morphogenesis involved in differentiation GO:0010771 2 0.019
regulation of cellular amine metabolic process GO:0033238 0 0.019
behavior GO:0007610 527 0.019
defense response to other organism GO:0098542 100 0.019
regulation of axon extension GO:0030516 20 0.019
ovulation GO:0030728 33 0.019
ribonucleotide metabolic process GO:0009259 99 0.019
regulation of phosphate metabolic process GO:0019220 81 0.019
cellular macromolecular complex assembly GO:0034622 184 0.019
Mouse
dorsal ventral axon guidance GO:0033563 19 0.018
negative regulation of response to stimulus GO:0048585 73 0.018
cellular response to unfolded protein GO:0034620 71 0.017
regulation of purine nucleotide metabolic process GO:1900542 37 0.016
oxoacid metabolic process GO:0043436 47 0.016
catabolic process GO:0009056 318 0.016
intracellular receptor signaling pathway GO:0030522 2 0.016
male anatomical structure morphogenesis GO:0090598 78 0.016
muscle attachment GO:0016203 3 0.016
striated muscle cell development GO:0055002 157 0.016
Zebrafish
defense response GO:0006952 296 0.016
regulation of molecular function GO:0065009 89 0.016
Fly
negative regulation of signaling GO:0023057 61 0.016
female gamete generation GO:0007292 254 0.016
peptidyl tyrosine phosphorylation GO:0018108 2 0.016
muscle cell development GO:0055001 158 0.016
Zebrafish
purine nucleotide metabolic process GO:0006163 95 0.015
macromolecular complex assembly GO:0065003 193 0.015
Mouse
regulation of localization GO:0032879 194 0.015
Mouse
mitotic cell cycle process GO:1903047 194 0.015
cell adhesion GO:0007155 21 0.015
Mouse Fly
negative regulation of post embryonic development GO:0048581 208 0.015
ribonucleoside metabolic process GO:0009119 98 0.015
negative chemotaxis GO:0050919 1 0.015
protein complex biogenesis GO:0070271 186 0.015
Mouse
adult behavior GO:0030534 3 0.015
negative regulation of neuron differentiation GO:0045665 4 0.015
axonal fasciculation GO:0007413 79 0.015
regulation of hormone secretion GO:0046883 2 0.015
protein complex assembly GO:0006461 186 0.014
Mouse
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.014
Fly
regulation of gene expression epigenetic GO:0040029 163 0.014
regulation of cellular ketone metabolic process GO:0010565 3 0.014
phosphorus metabolic process GO:0006793 232 0.014
Mouse
pharynx development GO:0060465 51 0.014
regulation of intracellular signal transduction GO:1902531 77 0.014
regulation of cell communication GO:0010646 176 0.014
Fly
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.014
phosphorylation GO:0016310 116 0.014
Mouse
organic acid metabolic process GO:0006082 47 0.014
inductive cell migration GO:0040039 145 0.014
oogenesis GO:0048477 229 0.014
cell type specific apoptotic process GO:0097285 4 0.014
basement membrane organization GO:0071711 3 0.013
posttranscriptional regulation of gene expression GO:0010608 166 0.013
male sex differentiation GO:0046661 86 0.013
amine metabolic process GO:0009308 15 0.012
apoptotic cell clearance GO:0043277 111 0.012
regulation of hydrolase activity GO:0051336 45 0.012
Fly
protein phosphorylation GO:0006468 85 0.012
ribonucleotide catabolic process GO:0009261 75 0.012
cell cell junction assembly GO:0007043 2 0.012
Fly
negative regulation of vulval development GO:0040027 206 0.012
positive regulation of catalytic activity GO:0043085 59 0.012
Fly
organonitrogen compound metabolic process GO:1901564 151 0.012
response to oxygen containing compound GO:1901700 44 0.012
reproductive behavior GO:0019098 387 0.012
positive regulation of embryonic development GO:0040019 3 0.012
apical junction assembly GO:0043297 1 0.012
glycosyl compound catabolic process GO:1901658 79 0.012
meiotic nuclear division GO:0007126 300 0.012
regulation of response to stimulus GO:0048583 243 0.012
Fly
myofibril assembly GO:0030239 154 0.012
phagocytosis GO:0006909 115 0.012
determination of bilateral symmetry GO:0009855 9 0.012
positive regulation of locomotion GO:0040017 42 0.011
positive regulation of cell migration GO:0030335 3 0.011
positive regulation of nematode larval development GO:0061063 54 0.011
myosin filament assembly GO:0031034 138 0.011
chromatin organization GO:0006325 32 0.011
myosin filament organization GO:0031033 138 0.011
organophosphate catabolic process GO:0046434 81 0.011
small gtpase mediated signal transduction GO:0007264 32 0.011
protein polymerization GO:0051258 26 0.011
Mouse
regulation of cell adhesion GO:0030155 6 0.011
lateral inhibition GO:0046331 3 0.011
cellular response to topologically incorrect protein GO:0035967 76 0.011
striated muscle myosin thick filament assembly GO:0071688 138 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
regulation of cytoskeleton organization GO:0051493 41 0.011
Mouse
ras protein signal transduction GO:0007265 31 0.011
positive regulation of axon extension GO:0045773 4 0.011
organic substance transport GO:0071702 113 0.011
cell matrix adhesion GO:0007160 1 0.011
development of primary male sexual characteristics GO:0046546 4 0.011
negative regulation of nematode larval development GO:0061064 208 0.011
regulation of cell cell adhesion GO:0022407 1 0.011
regulation of nucleotide catabolic process GO:0030811 35 0.011
cellular amine metabolic process GO:0044106 15 0.011
regulation of small gtpase mediated signal transduction GO:0051056 41 0.010
engulfment of apoptotic cell GO:0043652 94 0.010
carbohydrate derivative metabolic process GO:1901135 141 0.010
chromatin modification GO:0016568 32 0.010
membrane organization GO:0061024 135 0.010
establishment of protein localization to membrane GO:0090150 3 0.010
establishment or maintenance of cell polarity GO:0007163 63 0.010
Fly
anterior posterior pattern specification GO:0009952 27 0.010
adult locomotory behavior GO:0008344 1 0.010
regulation of multi organism process GO:0043900 69 0.010
regulation of apoptotic signaling pathway GO:2001233 1 0.010
positive regulation of epithelial cell proliferation GO:0050679 1 0.010
negative regulation of axon extension GO:0030517 2 0.010
organonitrogen compound catabolic process GO:1901565 90 0.010
glycosyl compound metabolic process GO:1901657 100 0.010

syg-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.052
myopathy DOID:423 0 0.022
muscular disease DOID:0080000 0 0.022
musculoskeletal system disease DOID:17 0 0.022
muscle tissue disease DOID:66 0 0.022
nervous system disease DOID:863 0 0.014