Caenorhabditis elegans

27 known processes

pat-12 (CELE_T17H7.4)

Protein PAT-12

pat-12 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.688
transport GO:0006810 1093 0.632
determination of adult lifespan GO:0008340 812 0.606
cell development GO:0048468 696 0.508
multicellular organismal reproductive process GO:0048609 815 0.386
homeostatic process GO:0042592 51 0.342
embryo development ending in birth or egg hatching GO:0009792 2992 0.314
negative regulation of biological process GO:0048519 567 0.310
negative regulation of response to stimulus GO:0048585 73 0.306
purine ribonucleotide metabolic process GO:0009150 95 0.295
cytoskeleton organization GO:0007010 339 0.286
regulation of cellular biosynthetic process GO:0031326 189 0.284
single organism reproductive process GO:0044702 1196 0.276
developmental process involved in reproduction GO:0003006 1165 0.262
single organism organelle organization GO:1902589 501 0.261
multicellular organismal aging GO:0010259 812 0.258
genitalia development GO:0048806 741 0.251
death GO:0016265 547 0.215
skin development GO:0043588 24 0.212
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.211
positive regulation of metabolic process GO:0009893 187 0.211
phosphorus metabolic process GO:0006793 232 0.210
single organism transport GO:0044765 447 0.201
regulation of molecular function GO:0065009 89 0.198
multicellular organismal reproductive behavior GO:0033057 384 0.197
neuron differentiation GO:0030182 217 0.184
cellular component movement GO:0006928 388 0.183
nucleobase containing compound metabolic process GO:0006139 406 0.176
nucleoside phosphate catabolic process GO:1901292 77 0.174
positive regulation of cellular process GO:0048522 332 0.172
cell cycle GO:0007049 526 0.170
organelle organization GO:0006996 783 0.163
actin filament based process GO:0030029 191 0.162
reproductive system development GO:0061458 850 0.159
aging GO:0007568 812 0.153
anatomical structure formation involved in morphogenesis GO:0048646 250 0.153
cell motility GO:0048870 313 0.152
response to abiotic stimulus GO:0009628 152 0.152
protein complex subunit organization GO:0071822 280 0.150
regulation of nitrogen compound metabolic process GO:0051171 222 0.150
nucleoside triphosphate metabolic process GO:0009141 87 0.144
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.144
reproductive structure development GO:0048608 850 0.140
cellular component biogenesis GO:0044085 297 0.136
regulation of cell communication GO:0010646 176 0.135
cellular nitrogen compound biosynthetic process GO:0044271 192 0.135
purine containing compound catabolic process GO:0072523 75 0.135
locomotion GO:0040011 1634 0.134
cell surface receptor signaling pathway GO:0007166 149 0.133
organelle fission GO:0048285 363 0.132
organ development GO:0048513 1102 0.128
muscle organ morphogenesis GO:0048644 4 0.126
regulation of primary metabolic process GO:0080090 292 0.118
heterocycle biosynthetic process GO:0018130 187 0.117
regulation of locomotion GO:0040012 161 0.116
programmed cell death GO:0012501 500 0.116
gene expression GO:0010467 412 0.113
vesicle mediated transport GO:0016192 852 0.113
signaling GO:0023052 401 0.112
single organism localization GO:1902578 518 0.111
endocytosis GO:0006897 819 0.110
negative regulation of cellular process GO:0048523 239 0.110
hermaphrodite genitalia development GO:0040035 734 0.109
nucleoside metabolic process GO:0009116 99 0.108
multi organism reproductive process GO:0044703 867 0.106
gamete generation GO:0007276 461 0.106
multicellular organism reproduction GO:0032504 819 0.103
regulation of metabolic process GO:0019222 478 0.103
cell cycle process GO:0022402 482 0.101
small molecule metabolic process GO:0044281 186 0.101
glycosyl compound catabolic process GO:1901658 79 0.100
digestive tract morphogenesis GO:0048546 76 0.099
tissue morphogenesis GO:0048729 65 0.098
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.098
regulation of catabolic process GO:0009894 57 0.096
regulation of multicellular organismal process GO:0051239 726 0.095
negative regulation of cell communication GO:0010648 61 0.094
regulation of biosynthetic process GO:0009889 189 0.094
phosphate containing compound metabolic process GO:0006796 232 0.093
apoptotic process GO:0006915 478 0.092
negative regulation of multicellular organismal process GO:0051241 236 0.091
organic cyclic compound biosynthetic process GO:1901362 195 0.091
regulation of biological quality GO:0065008 741 0.090
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.090
single organism catabolic process GO:0044712 129 0.086
regulation of response to stimulus GO:0048583 243 0.086
cellular component assembly GO:0022607 293 0.083
negative regulation of developmental process GO:0051093 227 0.080
sex differentiation GO:0007548 909 0.079
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.076
regulation of atp catabolic process GO:1903289 3 0.076
positive regulation of biosynthetic process GO:0009891 109 0.075
organelle localization GO:0051640 127 0.073
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.071
cellular biosynthetic process GO:0044249 315 0.070
meiotic nuclear division GO:0007126 300 0.070
localization of cell GO:0051674 313 0.069
cell death GO:0008219 547 0.069
molting cycle GO:0042303 281 0.069
regulation of macromolecule metabolic process GO:0060255 421 0.069
cellular response to chemical stimulus GO:0070887 129 0.068
post embryonic development GO:0009791 2152 0.068
purine nucleotide metabolic process GO:0006163 95 0.068
macromolecular complex subunit organization GO:0043933 320 0.067
regulation of actin filament based process GO:0032970 22 0.067
negative regulation of signal transduction GO:0009968 60 0.067
organelle assembly GO:0070925 214 0.066
regulation of programmed cell death GO:0043067 50 0.065
positive regulation of cellular metabolic process GO:0031325 178 0.064
establishment of localization GO:0051234 1171 0.064
post embryonic organ development GO:0048569 336 0.063
single organism cellular localization GO:1902580 72 0.063
negative regulation of signaling GO:0023057 61 0.063
regulation of purine nucleotide metabolic process GO:1900542 37 0.063
positive regulation of catabolic process GO:0009896 38 0.062
regulation of cellular metabolic process GO:0031323 305 0.061
ribonucleotide metabolic process GO:0009259 99 0.061
developmental growth GO:0048589 412 0.060
tube development GO:0035295 126 0.059
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.059
inductive cell migration GO:0040039 145 0.058
multi multicellular organism process GO:0044706 390 0.058
regulation of signal transduction GO:0009966 135 0.058
regulation of rna biosynthetic process GO:2001141 165 0.057
ion transport GO:0006811 113 0.056
muscle cell cellular homeostasis GO:0046716 5 0.056
positive regulation of multicellular organismal process GO:0051240 417 0.055
organic cyclic compound catabolic process GO:1901361 119 0.054
female gamete generation GO:0007292 254 0.054
embryonic morphogenesis GO:0048598 152 0.053
cellular macromolecule localization GO:0070727 75 0.053
microtubule based process GO:0007017 182 0.053
macromolecule localization GO:0033036 771 0.053
muscle fiber development GO:0048747 2 0.053
regulation of gene expression GO:0010468 366 0.053
positive regulation of phosphorus metabolic process GO:0010562 56 0.052
macromolecule biosynthetic process GO:0009059 250 0.052
maintenance of location GO:0051235 580 0.051
ribonucleoside triphosphate metabolic process GO:0009199 87 0.051
purine nucleoside metabolic process GO:0042278 92 0.050
lipid storage GO:0019915 565 0.050
lipid localization GO:0010876 573 0.049
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.049
actin cytoskeleton organization GO:0030036 184 0.048
positive regulation of molecular function GO:0044093 61 0.048
organic substance biosynthetic process GO:1901576 323 0.048
protein metabolic process GO:0019538 422 0.047
cellular macromolecule biosynthetic process GO:0034645 247 0.047
rna biosynthetic process GO:0032774 169 0.047
positive regulation of cellular catabolic process GO:0031331 35 0.046
purine nucleoside triphosphate catabolic process GO:0009146 72 0.046
gonad development GO:0008406 840 0.046
cell part morphogenesis GO:0032990 152 0.045
ribonucleoside metabolic process GO:0009119 98 0.045
biosynthetic process GO:0009058 323 0.045
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.045
positive regulation of cell death GO:0010942 38 0.045
tube morphogenesis GO:0035239 79 0.044
nucleoside phosphate metabolic process GO:0006753 108 0.044
collagen and cuticulin based cuticle development GO:0040002 99 0.044
ribonucleoside triphosphate catabolic process GO:0009203 72 0.044
carbohydrate derivative metabolic process GO:1901135 141 0.043
response to organic substance GO:0010033 131 0.043
behavior GO:0007610 527 0.043
regulation of purine nucleotide catabolic process GO:0033121 35 0.043
digestive system development GO:0055123 122 0.042
response to external stimulus GO:0009605 289 0.042
mitotic cell cycle process GO:1903047 194 0.042
positive regulation of cellular biosynthetic process GO:0031328 109 0.041
positive regulation of response to stimulus GO:0048584 55 0.041
nucleobase containing compound biosynthetic process GO:0034654 184 0.041
actin filament bundle assembly GO:0051017 3 0.041
cellular nitrogen compound catabolic process GO:0044270 119 0.041
establishment of organelle localization GO:0051656 123 0.040
organophosphate catabolic process GO:0046434 81 0.040
regulation of nucleotide metabolic process GO:0006140 37 0.040
development of primary sexual characteristics GO:0045137 840 0.040
positive regulation of gene expression GO:0010628 112 0.039
striated muscle cell development GO:0055002 157 0.039
nucleoside catabolic process GO:0009164 78 0.038
cellular localization GO:0051641 360 0.038
epithelium development GO:0060429 68 0.038
digestive tract development GO:0048565 122 0.038
chromosome segregation GO:0007059 180 0.038
regulation of multicellular organismal development GO:2000026 317 0.037
negative regulation of nematode larval development GO:0061064 208 0.037
regulation of multicellular organism growth GO:0040014 373 0.037
regulation of developmental growth GO:0048638 389 0.037
carbohydrate derivative catabolic process GO:1901136 82 0.037
positive regulation of transcription dna templated GO:0045893 102 0.037
response to chemical GO:0042221 356 0.036
phosphorylation GO:0016310 116 0.036
muscle tissue development GO:0060537 1 0.036
protein complex biogenesis GO:0070271 186 0.036
regulation of nucleotide catabolic process GO:0030811 35 0.036
organic substance catabolic process GO:1901575 294 0.035
regulation of signaling GO:0023051 172 0.035
positive regulation of nucleotide catabolic process GO:0030813 28 0.035
spicule insertion GO:0034609 2 0.035
regulation of cell death GO:0010941 65 0.034
regulation of phosphate metabolic process GO:0019220 81 0.034
meiotic cell cycle GO:0051321 335 0.034
receptor mediated endocytosis GO:0006898 715 0.034
immune response GO:0006955 192 0.034
learning GO:0007612 21 0.033
glycosyl compound metabolic process GO:1901657 100 0.033
nucleic acid metabolic process GO:0090304 299 0.033
response to osmotic stress GO:0006970 29 0.033
regulation of catalytic activity GO:0050790 78 0.032
carboxylic acid metabolic process GO:0019752 34 0.032
purine ribonucleoside metabolic process GO:0046128 92 0.032
cellular response to stress GO:0033554 162 0.032
nucleotide metabolic process GO:0009117 108 0.032
positive regulation of growth GO:0045927 369 0.031
taxis GO:0042330 128 0.031
cation transport GO:0006812 78 0.031
canonical wnt signaling pathway GO:0060070 3 0.031
regulation of protein localization GO:0032880 50 0.031
macromolecule catabolic process GO:0009057 202 0.031
aromatic compound biosynthetic process GO:0019438 192 0.030
epithelial tube morphogenesis GO:0060562 1 0.030
single organism signaling GO:0044700 401 0.030
gastrulation GO:0007369 58 0.030
cellular catabolic process GO:0044248 199 0.030
macromolecular complex assembly GO:0065003 193 0.029
small gtpase mediated signal transduction GO:0007264 32 0.029
cell projection organization GO:0030030 231 0.029
protein modification process GO:0036211 207 0.029
purine nucleoside catabolic process GO:0006152 75 0.029
regulation of cytoskeleton organization GO:0051493 41 0.029
multi organism reproductive behavior GO:0044705 387 0.028
positive regulation of developmental growth GO:0048639 354 0.028
neuron projection development GO:0031175 187 0.028
skeletal muscle thin filament assembly GO:0030240 3 0.028
regulation of cytoplasmic transport GO:1903649 3 0.028
cell proliferation GO:0008283 116 0.028
transcription dna templated GO:0006351 168 0.028
actin filament organization GO:0007015 21 0.028
dendrite development GO:0016358 42 0.027
somatic muscle development GO:0007525 1 0.027
posttranscriptional regulation of gene expression GO:0010608 166 0.027
inorganic cation transmembrane transport GO:0098662 46 0.026
protein complex assembly GO:0006461 186 0.026
cell migration GO:0016477 306 0.026
generation of neurons GO:0048699 235 0.026
membrane organization GO:0061024 135 0.026
establishment of localization in cell GO:0051649 318 0.026
apical junction assembly GO:0043297 1 0.026
regulation of protein metabolic process GO:0051246 81 0.026
regulation of developmental process GO:0050793 684 0.026
anatomical structure homeostasis GO:0060249 11 0.026
response to external biotic stimulus GO:0043207 101 0.026
single organism intracellular transport GO:1902582 70 0.025
positive regulation of rna metabolic process GO:0051254 103 0.025
regulation of apoptotic signaling pathway GO:2001233 1 0.025
purine ribonucleoside catabolic process GO:0046130 75 0.025
neuron development GO:0048666 199 0.024
sexual reproduction GO:0019953 546 0.024
cell morphogenesis involved in differentiation GO:0000904 112 0.024
defense response GO:0006952 296 0.024
reproductive behavior GO:0019098 387 0.024
nucleobase containing compound catabolic process GO:0034655 114 0.023
negative regulation of gene expression GO:0010629 217 0.023
regulation of organelle organization GO:0033043 164 0.023
actomyosin structure organization GO:0031032 154 0.023
heterocycle catabolic process GO:0046700 119 0.023
negative regulation of vulval development GO:0040027 206 0.023
head development GO:0060322 1 0.022
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.022
positive regulation of nucleoside metabolic process GO:0045979 28 0.022
purine ribonucleoside monophosphate metabolic process GO:0009167 43 0.022
axon development GO:0061564 163 0.022
multicellular organism growth GO:0035264 385 0.022
regulation of macromolecule biosynthetic process GO:0010556 189 0.022
transmembrane transport GO:0055085 110 0.021
regulation of rna metabolic process GO:0051252 173 0.021
regulation of nematode larval development GO:0061062 260 0.021
chemical homeostasis GO:0048878 29 0.021
dicarboxylic acid transport GO:0006835 5 0.021
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.021
positive regulation of locomotion GO:0040017 42 0.020
catabolic process GO:0009056 318 0.020
negative regulation of metabolic process GO:0009892 240 0.020
positive regulation of developmental process GO:0051094 408 0.020
proximal distal pattern formation GO:0009954 6 0.020
establishment of cell polarity GO:0030010 46 0.020
negative regulation of macromolecule metabolic process GO:0010605 229 0.020
locomotory behavior GO:0007626 40 0.020
metal ion transport GO:0030001 49 0.020
striated muscle myosin thick filament assembly GO:0071688 138 0.020
regulation of transport GO:0051049 91 0.020
regulation of transcription dna templated GO:0006355 164 0.019
cellular component morphogenesis GO:0032989 318 0.019
purine nucleoside triphosphate metabolic process GO:0009144 87 0.019
growth GO:0040007 562 0.019
regulation of growth GO:0040008 409 0.019
positive regulation of multicellular organism growth GO:0040018 352 0.019
purine containing compound metabolic process GO:0072521 95 0.019
cellular protein metabolic process GO:0044267 279 0.019
regulation of cell development GO:0060284 49 0.019
regulation of cell proliferation GO:0042127 105 0.019
nucleobase containing small molecule metabolic process GO:0055086 115 0.019
regulation of protein kinase activity GO:0045859 28 0.018
multi organism behavior GO:0051705 389 0.018
macromolecule modification GO:0043412 218 0.018
epidermis development GO:0008544 24 0.018
cellular protein modification process GO:0006464 207 0.018
positive regulation of catalytic activity GO:0043085 59 0.018
peptidyl amino acid modification GO:0018193 58 0.018
nucleoside triphosphate catabolic process GO:0009143 72 0.018
purine nucleotide catabolic process GO:0006195 75 0.017
sensory organ morphogenesis GO:0090596 2 0.017
protein localization GO:0008104 205 0.017
monovalent inorganic cation transport GO:0015672 33 0.017
actin filament bundle organization GO:0061572 3 0.017
actin filament based movement GO:0030048 4 0.017
rho protein signal transduction GO:0007266 2 0.017
positive regulation of phosphate metabolic process GO:0045937 56 0.016
rna metabolic process GO:0016070 228 0.016
adult behavior GO:0030534 3 0.016
organic acid metabolic process GO:0006082 47 0.016
single organism membrane organization GO:0044802 35 0.016
cellular component assembly involved in morphogenesis GO:0010927 183 0.016
response to inorganic substance GO:0010035 50 0.016
response to acid chemical GO:0001101 4 0.016
body morphogenesis GO:0010171 620 0.016
adult locomotory behavior GO:0008344 1 0.016
gtp metabolic process GO:0046039 46 0.015
regulation of cell projection organization GO:0031344 38 0.015
oxoacid metabolic process GO:0043436 47 0.015
intracellular signal transduction GO:0035556 96 0.015
actin mediated cell contraction GO:0070252 3 0.015
regulation of behavior GO:0050795 97 0.015
signal transduction GO:0007165 317 0.015
regulation of localization GO:0032879 194 0.015
response to extracellular stimulus GO:0009991 38 0.015
mitotic sister chromatid segregation GO:0000070 38 0.015
regulation of anatomical structure size GO:0090066 46 0.014
transcription from rna polymerase ii promoter GO:0006366 149 0.014
er nucleus signaling pathway GO:0006984 66 0.014
cell morphogenesis GO:0000902 163 0.014
atp metabolic process GO:0046034 42 0.014
spindle localization GO:0051653 51 0.014
cellular response to organic substance GO:0071310 119 0.014
organic substance transport GO:0071702 113 0.014
positive regulation of calcium ion transport GO:0051928 1 0.014
learning or memory GO:0007611 27 0.014
cytosolic calcium ion homeostasis GO:0051480 2 0.014
secretion GO:0046903 147 0.014
regulation of small gtpase mediated signal transduction GO:0051056 41 0.014
cellular protein complex localization GO:0034629 3 0.014
regulation of cellular component movement GO:0051270 62 0.014
regulation of canonical wnt signaling pathway GO:0060828 1 0.014
regulation of cellular ketone metabolic process GO:0010565 3 0.014
positive regulation of nucleotide metabolic process GO:0045981 28 0.013
negative regulation of cellular component organization GO:0051129 33 0.013
negative regulation of gene expression epigenetic GO:0045814 2 0.013
endoderm development GO:0007492 20 0.013
regulation of atpase activity GO:0043462 3 0.013
apoptotic mitochondrial changes GO:0008637 2 0.013
apoptotic cell clearance GO:0043277 111 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 28 0.013
positive regulation of cysteine type endopeptidase activity GO:2001056 3 0.013
atp catabolic process GO:0006200 27 0.013
regulation of nucleoside metabolic process GO:0009118 37 0.013
vulval development GO:0040025 333 0.012
cellular homeostasis GO:0019725 22 0.012
protein oligomerization GO:0051259 4 0.012
mitochondrion organization GO:0007005 20 0.012
positive regulation of signaling GO:0023056 66 0.012
nucleotide catabolic process GO:0009166 77 0.012
dna metabolic process GO:0006259 74 0.012
germ cell development GO:0007281 351 0.012
regulation of phosphorus metabolic process GO:0051174 81 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 28 0.012
gene silencing GO:0016458 143 0.012
mitotic nuclear division GO:0007067 89 0.012
negative regulation of cellular metabolic process GO:0031324 95 0.012
establishment of mitotic spindle orientation GO:0000132 28 0.012
muscle cell differentiation GO:0042692 171 0.012
protein phosphorylation GO:0006468 85 0.011
positive regulation of protein metabolic process GO:0051247 45 0.011
regulation of gene expression epigenetic GO:0040029 163 0.011
cell type specific apoptotic process GO:0097285 4 0.011
organonitrogen compound metabolic process GO:1901564 151 0.011
myosin filament organization GO:0031033 138 0.011
negative regulation of cellular biosynthetic process GO:0031327 65 0.011
skeletal muscle organ development GO:0060538 3 0.011
positive regulation of cell communication GO:0010647 69 0.011
cell junction organization GO:0034330 18 0.011
mitotic spindle organization GO:0007052 81 0.011
regulation of actin cytoskeleton organization GO:0032956 17 0.011
male gamete generation GO:0048232 41 0.011
response to metal ion GO:0010038 33 0.011
regulation of cellular protein metabolic process GO:0032268 75 0.011
oogenesis GO:0048477 229 0.011
g protein coupled receptor signaling pathway GO:0007186 46 0.011
response to wounding GO:0009611 4 0.011
establishment or maintenance of cell polarity GO:0007163 63 0.011
cellular protein localization GO:0034613 75 0.011
positive regulation of programmed cell death GO:0043068 27 0.010
positive regulation of neuron differentiation GO:0045666 4 0.010
regulation of apoptotic process GO:0042981 36 0.010
response to bacterium GO:0009617 86 0.010
regulation of neurogenesis GO:0050767 40 0.010
inorganic ion transmembrane transport GO:0098660 54 0.010
positive regulation of protein transport GO:0051222 4 0.010
regulation of cell motility GO:2000145 57 0.010
positive regulation of macromolecule metabolic process GO:0010604 149 0.010
positive regulation of nucleic acid templated transcription GO:1903508 102 0.010
regulation of post embryonic development GO:0048580 260 0.010
regulation of cellular localization GO:0060341 42 0.010

pat-12 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.475
cardiovascular system disease DOID:1287 0 0.475
myopathy DOID:423 0 0.427
muscular disease DOID:0080000 0 0.427
musculoskeletal system disease DOID:17 0 0.427
muscle tissue disease DOID:66 0 0.427
heart disease DOID:114 0 0.278
cardiomyopathy DOID:0050700 0 0.278
dilated cardiomyopathy DOID:12930 0 0.219
intrinsic cardiomyopathy DOID:0060036 0 0.219
muscular dystrophy DOID:9884 0 0.027
emery dreifuss muscular dystrophy DOID:11726 0 0.027
hypertrophic cardiomyopathy DOID:11984 0 0.025
congenital muscular dystrophy DOID:0050557 0 0.019
lipodystrophy DOID:811 0 0.012
skin disease DOID:37 0 0.012
integumentary system disease DOID:16 0 0.012
familial partial lipodystrophy DOID:0050440 0 0.012
progeria DOID:3911 0 0.010