Caenorhabditis elegans

13 known processes

hil-6 (CELE_F59A7.4)

Protein HIL-6

hil-6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
developmental process involved in reproduction GO:0003006 1165 0.374
Worm
embryo development GO:0009790 3052 0.323
embryo development ending in birth or egg hatching GO:0009792 2992 0.289
post embryonic development GO:0009791 2152 0.283
reproductive structure development GO:0048608 850 0.281
single organism reproductive process GO:0044702 1196 0.277
Mouse Worm
hermaphrodite genitalia development GO:0040035 734 0.249
gonad development GO:0008406 840 0.233
development of primary sexual characteristics GO:0045137 840 0.206
gamete generation GO:0007276 461 0.195
Mouse Worm
death GO:0016265 547 0.192
Worm
reproductive system development GO:0061458 850 0.192
organ development GO:0048513 1102 0.182
cell death GO:0008219 547 0.171
Worm
cell development GO:0048468 696 0.156
Worm
genitalia development GO:0048806 741 0.152
multicellular organism reproduction GO:0032504 819 0.149
Mouse Worm
sex differentiation GO:0007548 909 0.145
apoptotic process GO:0006915 478 0.143
Worm
locomotion GO:0040011 1634 0.125
Mouse Worm
sexual reproduction GO:0019953 546 0.123
Mouse Worm
multicellular organismal reproductive process GO:0048609 815 0.123
Mouse Worm
regulation of nitrogen compound metabolic process GO:0051171 222 0.122
body morphogenesis GO:0010171 620 0.118
regulation of metabolic process GO:0019222 478 0.114
cellular component movement GO:0006928 388 0.107
Mouse
growth GO:0040007 562 0.099
programmed cell death GO:0012501 500 0.097
Worm
meiotic nuclear division GO:0007126 300 0.090
Worm
oviposition GO:0018991 364 0.087
Worm
multicellular organismal reproductive behavior GO:0033057 384 0.086
Worm
protein complex subunit organization GO:0071822 280 0.084
Mouse
positive regulation of developmental process GO:0051094 408 0.076
positive regulation of cellular metabolic process GO:0031325 178 0.075
multi organism reproductive process GO:0044703 867 0.075
Mouse Worm
positive regulation of cellular process GO:0048522 332 0.075
Worm
regulation of biological quality GO:0065008 741 0.072
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.070
Worm
meiotic chromosome segregation GO:0045132 139 0.068
Worm
macromolecule localization GO:0033036 771 0.065
negative regulation of biological process GO:0048519 567 0.065
Worm
reproductive behavior GO:0019098 387 0.065
Worm
establishment of localization GO:0051234 1171 0.063
multicellular organismal aging GO:0010259 812 0.063
germ cell development GO:0007281 351 0.062
Worm
cell cycle GO:0007049 526 0.061
Worm
maintenance of location GO:0051235 580 0.061
generation of neurons GO:0048699 235 0.061
nucleobase containing compound metabolic process GO:0006139 406 0.061
Mouse
lipid storage GO:0019915 565 0.057
multi organism reproductive behavior GO:0044705 387 0.057
Worm
cellular component biogenesis GO:0044085 297 0.057
Mouse
regulation of developmental process GO:0050793 684 0.056
lipid localization GO:0010876 573 0.056
vesicle mediated transport GO:0016192 852 0.056
positive regulation of metabolic process GO:0009893 187 0.055
regulation of macromolecule metabolic process GO:0060255 421 0.055
regulation of cellular metabolic process GO:0031323 305 0.055
multi organism behavior GO:0051705 389 0.054
Worm
gene expression GO:0010467 412 0.054
regulation of macromolecule biosynthetic process GO:0010556 189 0.053
aging GO:0007568 812 0.053
positive regulation of multicellular organismal process GO:0051240 417 0.053
determination of adult lifespan GO:0008340 812 0.052
cell motility GO:0048870 313 0.051
Mouse
meiotic cell cycle GO:0051321 335 0.050
Worm
cytoskeleton organization GO:0007010 339 0.050
organelle organization GO:0006996 783 0.049
Mouse Worm
endocytosis GO:0006897 819 0.049
regulation of gene expression GO:0010468 366 0.049
cell migration GO:0016477 306 0.048
regulation of multicellular organismal process GO:0051239 726 0.048
multi multicellular organism process GO:0044706 390 0.048
Worm
neuron development GO:0048666 199 0.048
protein metabolic process GO:0019538 422 0.048
head development GO:0060322 1 0.048
regulation of multicellular organismal development GO:2000026 317 0.047
macromolecule biosynthetic process GO:0009059 250 0.046
transport GO:0006810 1093 0.046
positive regulation of developmental growth GO:0048639 354 0.046
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.045
positive regulation of growth GO:0045927 369 0.045
neuron differentiation GO:0030182 217 0.045
behavior GO:0007610 527 0.045
Worm
negative regulation of macromolecule metabolic process GO:0010605 229 0.044
female gamete generation GO:0007292 254 0.044
oogenesis GO:0048477 229 0.044
neurogenesis GO:0022008 236 0.044
cellular localization GO:0051641 360 0.043
cellular component assembly GO:0022607 293 0.043
Mouse
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.043
meiotic cell cycle process GO:1903046 170 0.043
Worm
receptor mediated endocytosis GO:0006898 715 0.043
cell projection organization GO:0030030 231 0.043
negative regulation of metabolic process GO:0009892 240 0.042
chemotaxis GO:0006935 120 0.042
organic substance biosynthetic process GO:1901576 323 0.041
single organism localization GO:1902578 518 0.041
response to external stimulus GO:0009605 289 0.041
macromolecular complex subunit organization GO:0043933 320 0.041
Mouse
signal transduction GO:0007165 317 0.041
neuron projection guidance GO:0097485 82 0.041
skeletal muscle organ development GO:0060538 3 0.040
response to chemical GO:0042221 356 0.040
developmental growth GO:0048589 412 0.039
single organism signaling GO:0044700 401 0.039
regulation of growth GO:0040008 409 0.038
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.038
negative regulation of gene expression GO:0010629 217 0.038
muscle tissue development GO:0060537 1 0.038
cellular component morphogenesis GO:0032989 318 0.038
sensory organ morphogenesis GO:0090596 2 0.037
positive regulation of cellular biosynthetic process GO:0031328 109 0.037
regulation of cell cycle GO:0051726 194 0.037
Worm
nervous system development GO:0007399 253 0.037
positive regulation of multicellular organism growth GO:0040018 352 0.036
negative regulation of cellular process GO:0048523 239 0.036
Worm
molting cycle GO:0042303 281 0.036
nucleic acid metabolic process GO:0090304 299 0.036
Mouse
single organism organelle organization GO:1902589 501 0.036
biosynthetic process GO:0009058 323 0.035
regulation of multicellular organism growth GO:0040014 373 0.035
cellular biosynthetic process GO:0044249 315 0.035
localization of cell GO:0051674 313 0.035
Mouse
regulation of primary metabolic process GO:0080090 292 0.035
positive regulation of neurogenesis GO:0050769 4 0.035
vulval development GO:0040025 333 0.034
defense response GO:0006952 296 0.034
cell division GO:0051301 262 0.033
cellular macromolecule biosynthetic process GO:0034645 247 0.033
regulation of biosynthetic process GO:0009889 189 0.033
actin filament based process GO:0030029 191 0.033
striated muscle cell differentiation GO:0051146 158 0.033
phosphate containing compound metabolic process GO:0006796 232 0.033
macromolecule modification GO:0043412 218 0.033
regulation of developmental growth GO:0048638 389 0.032
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.032
signaling GO:0023052 401 0.032
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.031
positive regulation of rna metabolic process GO:0051254 103 0.031
cell morphogenesis GO:0000902 163 0.031
regulation of cellular component organization GO:0051128 248 0.031
cellular protein complex assembly GO:0043623 178 0.031
cellular protein metabolic process GO:0044267 279 0.031
positive regulation of macromolecule metabolic process GO:0010604 149 0.030
regulation of vulval development GO:0040028 248 0.030
neuron projection development GO:0031175 187 0.030
macromolecular complex assembly GO:0065003 193 0.030
Mouse
response to wounding GO:0009611 4 0.030
muscle structure development GO:0061061 191 0.030
cellular macromolecular complex assembly GO:0034622 184 0.030
innate immune response GO:0045087 190 0.029
regulation of post embryonic development GO:0048580 260 0.029
anatomical structure formation involved in morphogenesis GO:0048646 250 0.029
regulation of cellular biosynthetic process GO:0031326 189 0.029
establishment of localization in cell GO:0051649 318 0.029
multicellular organism growth GO:0035264 385 0.028
protein modification process GO:0036211 207 0.028
protein complex biogenesis GO:0070271 186 0.028
regulation of organ morphogenesis GO:2000027 4 0.028
actin cytoskeleton organization GO:0030036 184 0.028
regulation of nematode larval development GO:0061062 260 0.028
muscle cell development GO:0055001 158 0.027
small molecule metabolic process GO:0044281 186 0.027
muscle cell differentiation GO:0042692 171 0.027
negative regulation of multicellular organismal process GO:0051241 236 0.027
axon guidance GO:0007411 82 0.026
organelle fission GO:0048285 363 0.026
Worm
cellular protein modification process GO:0006464 207 0.026
cellular response to stress GO:0033554 162 0.026
protein complex assembly GO:0006461 186 0.026
gene silencing GO:0016458 143 0.026
cell cycle process GO:0022402 482 0.026
Worm
microtubule based process GO:0007017 182 0.026
cell morphogenesis involved in differentiation GO:0000904 112 0.026
myosin filament assembly GO:0031034 138 0.026
negative regulation of vulval development GO:0040027 206 0.025
digestive system development GO:0055123 122 0.025
positive regulation of biosynthetic process GO:0009891 109 0.025
negative regulation of nematode larval development GO:0061064 208 0.025
regulation of cell cycle process GO:0010564 145 0.024
negative regulation of developmental process GO:0051093 227 0.024
transcription dna templated GO:0006351 168 0.024
cell proliferation GO:0008283 116 0.024
post embryonic organ development GO:0048569 336 0.024
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.024
striated muscle cell development GO:0055002 157 0.024
positive regulation of nucleic acid templated transcription GO:1903508 102 0.024
cell part morphogenesis GO:0032990 152 0.024
rna metabolic process GO:0016070 228 0.024
tube development GO:0035295 126 0.024
regulation of meiosis GO:0040020 94 0.024
regulation of rna metabolic process GO:0051252 173 0.024
embryonic morphogenesis GO:0048598 152 0.023
positive regulation of gene expression GO:0010628 112 0.023
organelle assembly GO:0070925 214 0.023
immune response GO:0006955 192 0.023
single organism transport GO:0044765 447 0.023
axon development GO:0061564 163 0.023
regulation of meiotic cell cycle GO:0051445 136 0.022
Worm
regulation of cell division GO:0051302 142 0.022
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.022
regulation of response to stimulus GO:0048583 243 0.022
chromosome organization GO:0051276 104 0.022
Mouse
rna biosynthetic process GO:0032774 169 0.022
taxis GO:0042330 128 0.022
chromosome segregation GO:0007059 180 0.022
Worm
axonogenesis GO:0007409 102 0.022
negative regulation of post embryonic development GO:0048581 208 0.022
regulation of nucleic acid templated transcription GO:1903506 165 0.021
protein localization GO:0008104 205 0.021
posttranscriptional regulation of gene expression GO:0010608 166 0.021
actomyosin structure organization GO:0031032 154 0.021
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.021
regulation of organelle organization GO:0033043 164 0.020
cell projection morphogenesis GO:0048858 148 0.020
striated muscle myosin thick filament assembly GO:0071688 138 0.020
inductive cell migration GO:0040039 145 0.020
response to abiotic stimulus GO:0009628 152 0.020
regulation of apoptotic signaling pathway GO:2001233 1 0.020
cellular response to abiotic stimulus GO:0071214 4 0.020
organic substance catabolic process GO:1901575 294 0.020
regulation of cell proliferation GO:0042127 105 0.019
regulation of filopodium assembly GO:0051489 2 0.019
regulation of gene expression epigenetic GO:0040029 163 0.019
establishment of organelle localization GO:0051656 123 0.019
myosin filament organization GO:0031033 138 0.019
organonitrogen compound metabolic process GO:1901564 151 0.019
myofibril assembly GO:0030239 154 0.019
gene silencing by rna GO:0031047 143 0.019
aromatic compound biosynthetic process GO:0019438 192 0.019
macromolecule catabolic process GO:0009057 202 0.019
regulation of cell projection assembly GO:0060491 3 0.019
nucleobase containing compound biosynthetic process GO:0034654 184 0.019
neuron projection morphogenesis GO:0048812 114 0.018
cellular nitrogen compound catabolic process GO:0044270 119 0.018
nucleobase containing compound catabolic process GO:0034655 114 0.018
intracellular signal transduction GO:0035556 96 0.018
phosphorus metabolic process GO:0006793 232 0.018
positive regulation of transcription dna templated GO:0045893 102 0.018
oocyte axis specification GO:0007309 2 0.017
regulation of rna biosynthetic process GO:2001141 165 0.017
regulation of transcription dna templated GO:0006355 164 0.017
cell type specific apoptotic process GO:0097285 4 0.017
regulation of nuclear division GO:0051783 115 0.017
defense response to fungus GO:0050832 19 0.017
digestive tract morphogenesis GO:0048546 76 0.017
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.017
digestive tract development GO:0048565 122 0.016
ribosome biogenesis GO:0042254 4 0.016
nucleoside triphosphate metabolic process GO:0009141 87 0.016
organelle localization GO:0051640 127 0.016
regulation of signal transduction GO:0009966 135 0.016
positive regulation of neuron differentiation GO:0045666 4 0.016
muscle organ morphogenesis GO:0048644 4 0.016
regulation of cell communication GO:0010646 176 0.016
catabolic process GO:0009056 318 0.016
oocyte construction GO:0007308 2 0.015
regeneration GO:0031099 4 0.015
collagen and cuticulin based cuticle development GO:0040002 99 0.015
regulation of cellular ketone metabolic process GO:0010565 3 0.015
posttranscriptional gene silencing by rna GO:0035194 143 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.015
rna interference GO:0016246 137 0.015
aromatic compound catabolic process GO:0019439 116 0.015
carbohydrate derivative metabolic process GO:1901135 141 0.015
posttranscriptional gene silencing GO:0016441 143 0.015
negative regulation of cellular metabolic process GO:0031324 95 0.015
cellular nitrogen compound biosynthetic process GO:0044271 192 0.015
organic cyclic compound catabolic process GO:1901361 119 0.015
fertilization GO:0009566 63 0.015
Mouse
protein catabolic process GO:0030163 162 0.015
organic cyclic compound biosynthetic process GO:1901362 195 0.015
glycosyl compound metabolic process GO:1901657 100 0.014
phosphorylation GO:0016310 116 0.014
negative regulation of neurogenesis GO:0050768 4 0.014
epithelial tube morphogenesis GO:0060562 1 0.014
regulation of phosphate metabolic process GO:0019220 81 0.014
organophosphate metabolic process GO:0019637 125 0.014
cellular catabolic process GO:0044248 199 0.014
mitotic cell cycle process GO:1903047 194 0.013
tissue development GO:0009888 112 0.013
regulation of lipid metabolic process GO:0019216 4 0.013
negative regulation of cellular biosynthetic process GO:0031327 65 0.013
cellular response to chemical stimulus GO:0070887 129 0.013
cell substrate adhesion GO:0031589 1 0.013
nucleic acid templated transcription GO:0097659 169 0.013
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.013
regulation of protein metabolic process GO:0051246 81 0.013
regulation of epithelial cell proliferation GO:0050678 1 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.013
rrna metabolic process GO:0016072 3 0.013
cuticle development GO:0042335 100 0.012
membrane organization GO:0061024 135 0.012
regulation of cell differentiation GO:0045595 81 0.012
regulation of localization GO:0032879 194 0.012
heterocycle biosynthetic process GO:0018130 187 0.012
regulation of phosphorus metabolic process GO:0051174 81 0.012
carbohydrate derivative catabolic process GO:1901136 82 0.012
canonical wnt signaling pathway GO:0060070 3 0.012
neuron recognition GO:0008038 83 0.012
positive regulation of rna biosynthetic process GO:1902680 102 0.012
dauer larval development GO:0040024 92 0.012
regulation of response to wounding GO:1903034 1 0.012
ribonucleoside metabolic process GO:0009119 98 0.012
organic acid metabolic process GO:0006082 47 0.012
nucleoside phosphate metabolic process GO:0006753 108 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.012
cell fate commitment GO:0045165 139 0.012
rrna processing GO:0006364 3 0.012
ribose phosphate metabolic process GO:0019693 99 0.012
nucleotide metabolic process GO:0009117 108 0.012
nucleobase containing small molecule metabolic process GO:0055086 115 0.012
cell recognition GO:0008037 85 0.012
Mouse
heterocycle catabolic process GO:0046700 119 0.012
defense response to other organism GO:0098542 100 0.012
negative regulation of response to stimulus GO:0048585 73 0.012
cellular amino acid metabolic process GO:0006520 15 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.011
small gtpase mediated signal transduction GO:0007264 32 0.011
regulation of cellular amine metabolic process GO:0033238 0 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.011
axonal fasciculation GO:0007413 79 0.011
single fertilization GO:0007338 61 0.011
Mouse
transcription from rna polymerase ii promoter GO:0006366 149 0.011
epithelial cell proliferation GO:0050673 1 0.011
regulation of cell death GO:0010941 65 0.011
pigmentation GO:0043473 2 0.011
regulation of epithelial cell differentiation GO:0030856 4 0.011
single organism catabolic process GO:0044712 129 0.011
spermatogenesis GO:0007283 41 0.011
Mouse
synaptic growth at neuromuscular junction GO:0051124 1 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.011
neuromuscular junction development GO:0007528 2 0.011
purine nucleotide metabolic process GO:0006163 95 0.011
dna metabolic process GO:0006259 74 0.011
Mouse
purine nucleoside metabolic process GO:0042278 92 0.011
filopodium assembly GO:0046847 2 0.011
ras protein signal transduction GO:0007265 31 0.011
cellular ketone metabolic process GO:0042180 14 0.011
nucleotide catabolic process GO:0009166 77 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
regulation of locomotion GO:0040012 161 0.011
rna localization GO:0006403 3 0.011
regulation of intracellular signal transduction GO:1902531 77 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.011
protein phosphorylation GO:0006468 85 0.011
oxoacid metabolic process GO:0043436 47 0.010
negative regulation of gene expression epigenetic GO:0045814 2 0.010
response to biotic stimulus GO:0009607 101 0.010
neuron apoptotic process GO:0051402 4 0.010
regulation of synapse assembly GO:0051963 2 0.010
defense response to bacterium GO:0042742 86 0.010
tissue morphogenesis GO:0048729 65 0.010
regulation of cellular component movement GO:0051270 62 0.010
chromatin remodeling GO:0006338 2 0.010
axis specification GO:0009798 23 0.010
nucleoside catabolic process GO:0009164 78 0.010
internal peptidyl lysine acetylation GO:0018393 3 0.010
amine metabolic process GO:0009308 15 0.010

hil-6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.019
nervous system disease DOID:863 0 0.013
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010