Caenorhabditis elegans

92 known processes

erm-1 (CELE_C01G8.5)

Protein ERM-1

erm-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.657
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.442
molting cycle GO:0042303 281 0.353
organelle organization GO:0006996 783 0.320
apoptotic process GO:0006915 478 0.319
death GO:0016265 547 0.293
single organism organelle organization GO:1902589 501 0.262
programmed cell death GO:0012501 500 0.254
multi organism reproductive process GO:0044703 867 0.252
Fly
single organism transport GO:0044765 447 0.232
Mouse
cell death GO:0008219 547 0.213
regulation of multicellular organismal process GO:0051239 726 0.208
post embryonic development GO:0009791 2152 0.199
receptor mediated endocytosis GO:0006898 715 0.192
gonad development GO:0008406 840 0.180
negative regulation of biological process GO:0048519 567 0.179
embryo development ending in birth or egg hatching GO:0009792 2992 0.179
multicellular organism reproduction GO:0032504 819 0.172
Fly
single organism reproductive process GO:0044702 1196 0.169
Fly
establishment of localization GO:0051234 1171 0.162
aging GO:0007568 812 0.162
actin cytoskeleton organization GO:0030036 184 0.161
cellular component assembly GO:0022607 293 0.161
cytoskeleton organization GO:0007010 339 0.154
locomotion GO:0040011 1634 0.148
multicellular organismal aging GO:0010259 812 0.146
gamete generation GO:0007276 461 0.142
Fly
regulation of biological quality GO:0065008 741 0.135
Fly
reproductive structure development GO:0048608 850 0.133
single organism signaling GO:0044700 401 0.132
nucleoside phosphate metabolic process GO:0006753 108 0.130
anatomical structure formation involved in morphogenesis GO:0048646 250 0.130
regulation of nematode larval development GO:0061062 260 0.124
sex differentiation GO:0007548 909 0.117
regulation of signaling GO:0023051 172 0.115
transport GO:0006810 1093 0.114
endocytosis GO:0006897 819 0.112
cation transport GO:0006812 78 0.111
actin filament based process GO:0030029 191 0.110
phosphorus metabolic process GO:0006793 232 0.109
single organism cellular localization GO:1902580 72 0.108
single organism localization GO:1902578 518 0.107
negative regulation of vulval development GO:0040027 206 0.107
multicellular organismal reproductive behavior GO:0033057 384 0.106
Fly
multicellular organismal reproductive process GO:0048609 815 0.104
Fly
nucleotide metabolic process GO:0009117 108 0.104
phosphate containing compound metabolic process GO:0006796 232 0.103
cellular component assembly involved in morphogenesis GO:0010927 183 0.103
development of primary sexual characteristics GO:0045137 840 0.103
cellular component morphogenesis GO:0032989 318 0.102
ion transport GO:0006811 113 0.101
sexual reproduction GO:0019953 546 0.101
Fly
determination of adult lifespan GO:0008340 812 0.100
vesicle mediated transport GO:0016192 852 0.100
actomyosin structure organization GO:0031032 154 0.097
nucleobase containing compound metabolic process GO:0006139 406 0.096
negative regulation of post embryonic development GO:0048581 208 0.095
negative regulation of nematode larval development GO:0061064 208 0.095
developmental process involved in reproduction GO:0003006 1165 0.094
Fly
cellular protein complex assembly GO:0043623 178 0.093
organelle assembly GO:0070925 214 0.093
body morphogenesis GO:0010171 620 0.092
organ development GO:0048513 1102 0.091
Fly
establishment of protein localization to membrane GO:0090150 3 0.090
macromolecule localization GO:0033036 771 0.086
regulation of developmental process GO:0050793 684 0.085
striated muscle cell development GO:0055002 157 0.084
inorganic ion transmembrane transport GO:0098660 54 0.083
genitalia development GO:0048806 741 0.082
regulation of post embryonic development GO:0048580 260 0.082
carbohydrate derivative metabolic process GO:1901135 141 0.082
positive regulation of metabolic process GO:0009893 187 0.081
Human
purine ribonucleotide catabolic process GO:0009154 75 0.080
cell projection assembly GO:0030031 35 0.078
Mouse
regulation of cell death GO:0010941 65 0.077
muscle cell development GO:0055001 158 0.075
small molecule metabolic process GO:0044281 186 0.074
organonitrogen compound metabolic process GO:1901564 151 0.072
response to external stimulus GO:0009605 289 0.071
Fly
regulation of cation channel activity GO:2001257 3 0.070
signaling GO:0023052 401 0.069
defense response GO:0006952 296 0.067
multicellular organism growth GO:0035264 385 0.066
catabolic process GO:0009056 318 0.065
Fly
lipid storage GO:0019915 565 0.065
lipid localization GO:0010876 573 0.065
cellular component biogenesis GO:0044085 297 0.065
regulation of ion transmembrane transport GO:0034765 19 0.064
hermaphrodite genitalia development GO:0040035 734 0.063
reproductive behavior GO:0019098 387 0.062
Fly
maintenance of location GO:0051235 580 0.062
oogenesis GO:0048477 229 0.062
Fly
protein complex biogenesis GO:0070271 186 0.061
positive regulation of multicellular organism growth GO:0040018 352 0.060
cell development GO:0048468 696 0.060
ion transmembrane transport GO:0034220 91 0.059
regulation of developmental growth GO:0048638 389 0.059
regulation of multicellular organism growth GO:0040014 373 0.059
regulation of intracellular signal transduction GO:1902531 77 0.059
vulval development GO:0040025 333 0.059
regulation of transport GO:0051049 91 0.059
Fly
post embryonic organ development GO:0048569 336 0.058
Fly
negative regulation of metabolic process GO:0009892 240 0.058
striated muscle cell differentiation GO:0051146 158 0.057
cellular localization GO:0051641 360 0.057
cilium morphogenesis GO:0060271 33 0.056
membrane organization GO:0061024 135 0.055
cation transmembrane transport GO:0098655 59 0.055
regulation of signal transduction GO:0009966 135 0.055
regulation of vulval development GO:0040028 248 0.054
posttranscriptional gene silencing GO:0016441 143 0.054
developmental growth GO:0048589 412 0.054
positive regulation of developmental process GO:0051094 408 0.053
multi multicellular organism process GO:0044706 390 0.053
Fly
organelle localization GO:0051640 127 0.052
Fly
regulation of growth GO:0040008 409 0.052
regulation of gene expression epigenetic GO:0040029 163 0.052
establishment of localization in cell GO:0051649 318 0.052
Fly
ribose phosphate metabolic process GO:0019693 99 0.051
oviposition GO:0018991 364 0.051
metal ion transport GO:0030001 49 0.051
regulation of response to stimulus GO:0048583 243 0.050
meiotic nuclear division GO:0007126 300 0.049
cellular protein localization GO:0034613 75 0.049
microtubule based process GO:0007017 182 0.049
Fly
positive regulation of growth GO:0045927 369 0.048
positive regulation of developmental growth GO:0048639 354 0.048
gene silencing GO:0016458 143 0.048
signal transduction GO:0007165 317 0.048
regulation of metabolic process GO:0019222 478 0.047
Human
multi organism reproductive behavior GO:0044705 387 0.047
Fly
positive regulation of cellular process GO:0048522 332 0.047
Fly
cellular component movement GO:0006928 388 0.046
gene expression GO:0010467 412 0.046
Human
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.046
negative regulation of gene expression GO:0010629 217 0.045
regulation of macromolecule metabolic process GO:0060255 421 0.045
Human
regulation of cytoplasmic transport GO:1903649 3 0.045
regulation of gene expression GO:0010468 366 0.045
Human
oxoacid metabolic process GO:0043436 47 0.045
gtp catabolic process GO:0006184 46 0.045
cellular macromolecular complex assembly GO:0034622 184 0.045
response to chemical GO:0042221 356 0.045
Fly
regulation of multicellular organismal development GO:2000026 317 0.045
ribonucleoside triphosphate metabolic process GO:0009199 87 0.045
response to wounding GO:0009611 4 0.044
nucleoside metabolic process GO:0009116 99 0.044
posttranscriptional gene silencing by rna GO:0035194 143 0.043
regulation of cellular component organization GO:0051128 248 0.043
Fly
divalent metal ion transport GO:0070838 17 0.042
negative regulation of developmental process GO:0051093 227 0.041
collagen and cuticulin based cuticle development GO:0040002 99 0.041
regulation of cell projection assembly GO:0060491 3 0.040
organic acid metabolic process GO:0006082 47 0.040
ribonucleoside metabolic process GO:0009119 98 0.040
cuticle development GO:0042335 100 0.039
positive regulation of multicellular organismal process GO:0051240 417 0.038
negative regulation of multicellular organismal process GO:0051241 236 0.038
divalent inorganic cation transport GO:0072511 17 0.038
protein complex assembly GO:0006461 186 0.038
sensory organ morphogenesis GO:0090596 2 0.038
Fly
multi organism behavior GO:0051705 389 0.038
Fly
behavior GO:0007610 527 0.037
Fly
regulation of oviposition GO:0046662 43 0.037
muscle tissue development GO:0060537 1 0.037
gene silencing by rna GO:0031047 143 0.037
regulation of cell communication GO:0010646 176 0.037
protein metabolic process GO:0019538 422 0.037
Fly
fertilization GO:0009566 63 0.037
nucleobase containing small molecule metabolic process GO:0055086 115 0.037
inorganic cation transmembrane transport GO:0098662 46 0.037
transmembrane transport GO:0055085 110 0.036
growth GO:0040007 562 0.036
endomembrane system organization GO:0010256 22 0.035
establishment of organelle localization GO:0051656 123 0.035
Fly
protein complex subunit organization GO:0071822 280 0.035
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.034
carbohydrate metabolic process GO:0005975 34 0.034
reproductive system development GO:0061458 850 0.034
single organism intracellular transport GO:1902582 70 0.034
purine nucleoside triphosphate metabolic process GO:0009144 87 0.033
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.033
Fly
single organism membrane organization GO:0044802 35 0.033
germ cell development GO:0007281 351 0.033
Fly
organic substance biosynthetic process GO:1901576 323 0.032
cell surface receptor signaling pathway GO:0007166 149 0.032
cellular nitrogen compound biosynthetic process GO:0044271 192 0.032
regulation of catalytic activity GO:0050790 78 0.032
ribonucleoside catabolic process GO:0042454 77 0.032
ovulation GO:0030728 33 0.032
cell part morphogenesis GO:0032990 152 0.032
Fly
purine containing compound catabolic process GO:0072523 75 0.031
cilium organization GO:0044782 32 0.031
carboxylic acid metabolic process GO:0019752 34 0.031
myosin filament assembly GO:0031034 138 0.030
posttranscriptional regulation of gene expression GO:0010608 166 0.030
purine nucleotide catabolic process GO:0006195 75 0.030
muscle cell differentiation GO:0042692 171 0.030
regulation of ph GO:0006885 6 0.030
muscle structure development GO:0061061 191 0.030
striated muscle myosin thick filament assembly GO:0071688 138 0.029
cilium assembly GO:0042384 28 0.029
organic substance catabolic process GO:1901575 294 0.029
Fly
carbohydrate derivative catabolic process GO:1901136 82 0.029
female gamete generation GO:0007292 254 0.029
Fly
neuron differentiation GO:0030182 217 0.029
Fly
cell cycle GO:0007049 526 0.029
Fly
regulation of reproductive process GO:2000241 66 0.029
nervous system development GO:0007399 253 0.029
Fly
nucleoside phosphate catabolic process GO:1901292 77 0.028
guanosine containing compound catabolic process GO:1901069 48 0.028
negative regulation of cellular process GO:0048523 239 0.028
monovalent inorganic cation homeostasis GO:0055067 6 0.028
regulation of cellular metabolic process GO:0031323 305 0.027
glycosyl compound catabolic process GO:1901658 79 0.027
cell projection organization GO:0030030 231 0.027
Mouse Fly
neuron development GO:0048666 199 0.026
Fly
skeletal muscle organ development GO:0060538 3 0.026
protein modification process GO:0036211 207 0.026
small gtpase mediated signal transduction GO:0007264 32 0.026
regulation of filopodium assembly GO:0051489 2 0.026
phagocytosis engulfment GO:0006911 98 0.026
macromolecular complex subunit organization GO:0043933 320 0.026
biosynthetic process GO:0009058 323 0.026
monovalent inorganic cation transport GO:0015672 33 0.026
enzyme linked receptor protein signaling pathway GO:0007167 50 0.025
organic cyclic compound biosynthetic process GO:1901362 195 0.025
localization of cell GO:0051674 313 0.025
establishment or maintenance of cell polarity GO:0007163 63 0.025
Mouse Fly
regulation of organelle organization GO:0033043 164 0.025
Fly
nucleotide catabolic process GO:0009166 77 0.025
myosin filament organization GO:0031033 138 0.024
rna interference GO:0016246 137 0.024
intracellular transport GO:0046907 77 0.024
negative regulation of response to stimulus GO:0048585 73 0.024
positive regulation of cellular metabolic process GO:0031325 178 0.024
positive regulation of cell communication GO:0010647 69 0.024
ribonucleotide catabolic process GO:0009261 75 0.024
macromolecule biosynthetic process GO:0009059 250 0.024
regulation of apoptotic signaling pathway GO:2001233 1 0.024
system process GO:0003008 136 0.024
purine ribonucleotide metabolic process GO:0009150 95 0.024
regulation of cellular biosynthetic process GO:0031326 189 0.023
positive regulation of signaling GO:0023056 66 0.023
purine nucleoside catabolic process GO:0006152 75 0.023
calcium ion transport GO:0006816 16 0.023
positive regulation of response to stimulus GO:0048584 55 0.023
positive regulation of signal transduction GO:0009967 40 0.022
cellular macromolecule localization GO:0070727 75 0.022
guanosine containing compound metabolic process GO:1901068 49 0.022
organophosphate metabolic process GO:0019637 125 0.022
myofibril assembly GO:0030239 154 0.022
regulation of programmed cell death GO:0043067 50 0.022
aromatic compound catabolic process GO:0019439 116 0.022
gtp metabolic process GO:0046039 46 0.022
cellular nitrogen compound catabolic process GO:0044270 119 0.022
embryonic morphogenesis GO:0048598 152 0.021
Zebrafish
nucleoside triphosphate catabolic process GO:0009143 72 0.021
head development GO:0060322 1 0.021
regulation of localization GO:0032879 194 0.021
Human Fly
cellular macromolecule biosynthetic process GO:0034645 247 0.021
cell projection morphogenesis GO:0048858 148 0.021
Fly
oocyte construction GO:0007308 2 0.021
Fly
response to biotic stimulus GO:0009607 101 0.021
epithelial tube morphogenesis GO:0060562 1 0.021
Zebrafish
negative regulation of macromolecule metabolic process GO:0010605 229 0.021
heterocycle catabolic process GO:0046700 119 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.020
glycosylation GO:0070085 20 0.020
regulation of ion transport GO:0043269 39 0.020
purine ribonucleoside catabolic process GO:0046130 75 0.020
purine nucleoside metabolic process GO:0042278 92 0.020
inductive cell migration GO:0040039 145 0.020
cell fate commitment GO:0045165 139 0.020
cellular catabolic process GO:0044248 199 0.020
Fly
cellular protein modification process GO:0006464 207 0.020
negative regulation of signal transduction GO:0009968 60 0.020
nucleobase containing compound biosynthetic process GO:0034654 184 0.019
nucleoside triphosphate metabolic process GO:0009141 87 0.019
organophosphate catabolic process GO:0046434 81 0.019
positive regulation of nucleic acid templated transcription GO:1903508 102 0.019
organic substance transport GO:0071702 113 0.019
regulation of cell cycle process GO:0010564 145 0.019
Fly
organic cyclic compound catabolic process GO:1901361 119 0.019
meiotic cell cycle GO:0051321 335 0.018
organonitrogen compound catabolic process GO:1901565 90 0.018
negative regulation of ion transmembrane transporter activity GO:0032413 3 0.018
purine ribonucleoside metabolic process GO:0046128 92 0.018
positive regulation of biosynthetic process GO:0009891 109 0.018
generation of neurons GO:0048699 235 0.018
Fly
exocytosis GO:0006887 15 0.018
organelle fission GO:0048285 363 0.018
Fly
regulation of primary metabolic process GO:0080090 292 0.018
cellular amino acid metabolic process GO:0006520 15 0.018
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 34 0.018
regulation of response to wounding GO:1903034 1 0.018
single organism catabolic process GO:0044712 129 0.018
Fly
nucleobase containing compound catabolic process GO:0034655 114 0.017
positive regulation of rna biosynthetic process GO:1902680 102 0.017
purine nucleotide metabolic process GO:0006163 95 0.017
engulfment of apoptotic cell GO:0043652 94 0.017
apoptotic cell clearance GO:0043277 111 0.017
heterocycle biosynthetic process GO:0018130 187 0.017
negative regulation of transmembrane transport GO:0034763 3 0.017
response to inorganic substance GO:0010035 50 0.017
macromolecule modification GO:0043412 218 0.017
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.017
Fly
single fertilization GO:0007338 61 0.017
regulation of multi organism process GO:0043900 69 0.017
ribonucleoside triphosphate catabolic process GO:0009203 72 0.017
regulation of lipid metabolic process GO:0019216 4 0.017
cell substrate adhesion GO:0031589 1 0.017
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.017
regulation of syncytium formation by plasma membrane fusion GO:0060142 4 0.017
cell type specific apoptotic process GO:0097285 4 0.016
intracellular signal transduction GO:0035556 96 0.016
regulation of protein targeting GO:1903533 3 0.016
regulation of cellular component movement GO:0051270 62 0.016
Human
positive regulation of intracellular transport GO:0032388 2 0.016
regulation of protein import into nucleus GO:0042306 3 0.016
oocyte axis specification GO:0007309 2 0.015
Fly
filopodium assembly GO:0046847 2 0.015
phagocytosis GO:0006909 115 0.015
actin filament organization GO:0007015 21 0.015
membrane lipid biosynthetic process GO:0046467 2 0.015
secretion GO:0046903 147 0.015
adult behavior GO:0030534 3 0.015
g protein coupled receptor signaling pathway GO:0007186 46 0.015
negative regulation of cell communication GO:0010648 61 0.015
sphingolipid metabolic process GO:0006665 2 0.015
tissue morphogenesis GO:0048729 65 0.015
regulation of cellular ketone metabolic process GO:0010565 3 0.014
cellular biosynthetic process GO:0044249 315 0.014
cellular ion homeostasis GO:0006873 11 0.014
negative regulation of signaling GO:0023057 61 0.014
secretion by cell GO:0032940 138 0.014
regulation of cell proliferation GO:0042127 105 0.014
Fly
positive regulation of transcription dna templated GO:0045893 102 0.014
nucleoside catabolic process GO:0009164 78 0.014
cell migration GO:0016477 306 0.014
regulation of cellular ph GO:0030641 4 0.014
chromosome segregation GO:0007059 180 0.014
Fly
macromolecular complex assembly GO:0065003 193 0.014
nucleic acid templated transcription GO:0097659 169 0.014
regulation of anatomical structure size GO:0090066 46 0.014
positive regulation of cell death GO:0010942 38 0.014
digestive system development GO:0055123 122 0.013
Zebrafish
regulation of nitrogen compound metabolic process GO:0051171 222 0.013
cell morphogenesis involved in differentiation GO:0000904 112 0.013
Fly
protein localization GO:0008104 205 0.013
positive regulation of hydrolase activity GO:0051345 38 0.013
oocyte development GO:0048599 44 0.013
Fly
regulation of molecular function GO:0065009 89 0.013
positive regulation of cellular biosynthetic process GO:0031328 109 0.013
response to abiotic stimulus GO:0009628 152 0.013
regulation of catabolic process GO:0009894 57 0.013
regulation of rna metabolic process GO:0051252 173 0.013
regulation of secretion GO:0051046 29 0.013
ceramide metabolic process GO:0006672 2 0.013
positive regulation of protein transport GO:0051222 4 0.013
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.012
regulation of behavior GO:0050795 97 0.012
hormone metabolic process GO:0042445 3 0.012
carbohydrate derivative biosynthetic process GO:1901137 46 0.012
glycoprotein metabolic process GO:0009100 29 0.012
hydrogen transport GO:0006818 5 0.012
membrane invagination GO:0010324 98 0.012
purine nucleoside triphosphate catabolic process GO:0009146 72 0.012
cell matrix adhesion GO:0007160 1 0.012
transcription from rna polymerase ii promoter GO:0006366 149 0.012
establishment of nucleus localization GO:0040023 55 0.012
positive regulation of phosphorus metabolic process GO:0010562 56 0.012
regulation of macromolecule biosynthetic process GO:0010556 189 0.012
response to transition metal nanoparticle GO:1990267 18 0.012
digestive tract morphogenesis GO:0048546 76 0.012
Zebrafish
regulation of transcription dna templated GO:0006355 164 0.012
protein transport GO:0015031 45 0.012
rna metabolic process GO:0016070 228 0.012
positive regulation of programmed cell death GO:0043068 27 0.012
positive regulation of secretion GO:0051047 17 0.012
regulation of nuclear division GO:0051783 115 0.012
Fly
negative regulation of cellular component organization GO:0051129 33 0.012
organ morphogenesis GO:0009887 67 0.012
Fly
regulation of protein localization GO:0032880 50 0.011
amine metabolic process GO:0009308 15 0.011
epithelial cell proliferation GO:0050673 1 0.011
negative regulation of apoptotic process GO:0043066 17 0.011
rna biosynthetic process GO:0032774 169 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.011
establishment of protein localization GO:0045184 50 0.011
protein localization to membrane GO:0072657 11 0.011
pigmentation GO:0043473 2 0.011
negative regulation of gene expression epigenetic GO:0045814 2 0.011
ribonucleotide metabolic process GO:0009259 99 0.011
regulation of nucleic acid templated transcription GO:1903506 165 0.011
regulation of apoptotic process GO:0042981 36 0.010
regulation of nucleocytoplasmic transport GO:0046822 3 0.010
phosphorylation GO:0016310 116 0.010
cellular amide metabolic process GO:0043603 11 0.010
regulation of epithelial cell proliferation GO:0050678 1 0.010
lipid metabolic process GO:0006629 77 0.010
neuromuscular junction development GO:0007528 2 0.010
pronuclear migration GO:0035046 51 0.010
negative regulation of ion transmembrane transport GO:0034766 3 0.010
regulation of biosynthetic process GO:0009889 189 0.010
regeneration GO:0031099 4 0.010
protein oligomerization GO:0051259 4 0.010
single organism biosynthetic process GO:0044711 91 0.010
neuron projection development GO:0031175 187 0.010
Fly
regulation of protein metabolic process GO:0051246 81 0.010
regulation of locomotion GO:0040012 161 0.010
Human

erm-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.034
Human
nervous system disease DOID:863 0 0.020
Human
myopathy DOID:423 0 0.012
muscular disease DOID:0080000 0 0.012
heart disease DOID:114 0 0.012
cardiomyopathy DOID:0050700 0 0.012
cardiovascular system disease DOID:1287 0 0.012
musculoskeletal system disease DOID:17 0 0.012
muscle tissue disease DOID:66 0 0.012