Caenorhabditis elegans

25 known processes

irx-1 (CELE_C36F7.1)

Protein IRX-1

irx-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
locomotion GO:0040011 1634 0.622
Fly
cell migration GO:0016477 306 0.525
localization of cell GO:0051674 313 0.508
axonogenesis GO:0007409 102 0.477
Fly
axon guidance GO:0007411 82 0.457
Fly
cell motility GO:0048870 313 0.454
cellular component movement GO:0006928 388 0.434
Fly
establishment of localization GO:0051234 1171 0.430
Fly
post embryonic development GO:0009791 2152 0.425
chemotaxis GO:0006935 120 0.397
Fly
neuron projection morphogenesis GO:0048812 114 0.376
Fly
body morphogenesis GO:0010171 620 0.368
positive regulation of cellular process GO:0048522 332 0.360
Mouse Fly
sensory organ morphogenesis GO:0090596 2 0.359
Zebrafish Mouse Fly
transport GO:0006810 1093 0.358
Fly
organ morphogenesis GO:0009887 67 0.349
Zebrafish Mouse Fly
vesicle mediated transport GO:0016192 852 0.338
Fly
neuron projection guidance GO:0097485 82 0.331
Fly
regulation of organ morphogenesis GO:2000027 4 0.330
embryo development GO:0009790 3052 0.308
neuron projection development GO:0031175 187 0.301
Fly
tube development GO:0035295 126 0.301
Zebrafish Mouse
single organism organelle organization GO:1902589 501 0.294
embryo development ending in birth or egg hatching GO:0009792 2992 0.285
multicellular organismal reproductive process GO:0048609 815 0.283
Fly
cell projection organization GO:0030030 231 0.281
Fly
regulation of developmental process GO:0050793 684 0.275
Mouse
multicellular organism reproduction GO:0032504 819 0.268
Fly
cell projection morphogenesis GO:0048858 148 0.257
Fly
tissue morphogenesis GO:0048729 65 0.255
Zebrafish Mouse Fly
taxis GO:0042330 128 0.255
Fly
regulation of primary metabolic process GO:0080090 292 0.246
Mouse Fly
regulation of transcription dna templated GO:0006355 164 0.245
Mouse Fly
muscle tissue development GO:0060537 1 0.244
Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.232
Mouse Fly
muscle organ development GO:0007517 26 0.230
Mouse
cell part morphogenesis GO:0032990 152 0.223
Fly
regulation of multicellular organismal development GO:2000026 317 0.203
Mouse
positive regulation of macromolecule metabolic process GO:0010604 149 0.203
Mouse Fly
axon development GO:0061564 163 0.200
Fly
aromatic compound biosynthetic process GO:0019438 192 0.197
Mouse Fly
multi organism reproductive process GO:0044703 867 0.197
Fly
head development GO:0060322 1 0.195
Zebrafish
organelle organization GO:0006996 783 0.194
regulation of locomotion GO:0040012 161 0.194
signaling GO:0023052 401 0.191
muscle cell differentiation GO:0042692 171 0.190
Mouse Fly
positive regulation of cellular metabolic process GO:0031325 178 0.183
Mouse Fly
programmed cell death GO:0012501 500 0.183
muscle structure development GO:0061061 191 0.183
Mouse Fly
regulation of neurogenesis GO:0050767 40 0.179
Mouse
regulation of multicellular organismal process GO:0051239 726 0.179
Mouse
digestive tract development GO:0048565 122 0.179
Zebrafish
nucleic acid metabolic process GO:0090304 299 0.172
Mouse Fly
regulation of nitrogen compound metabolic process GO:0051171 222 0.171
Mouse Fly
anatomical structure formation involved in morphogenesis GO:0048646 250 0.171
Zebrafish Mouse Fly
organ development GO:0048513 1102 0.169
Zebrafish Mouse Fly
neurogenesis GO:0022008 236 0.168
Zebrafish Mouse Fly
regulation of signal transduction GO:0009966 135 0.162
sex differentiation GO:0007548 909 0.161
cell development GO:0048468 696 0.157
Zebrafish Mouse Fly
regulation of cellular metabolic process GO:0031323 305 0.157
Mouse Fly
gonad development GO:0008406 840 0.154
nucleobase containing compound biosynthetic process GO:0034654 184 0.153
Mouse Fly
oviposition GO:0018991 364 0.153
positive regulation of metabolic process GO:0009893 187 0.151
Mouse Fly
multi organism behavior GO:0051705 389 0.147
regulation of localization GO:0032879 194 0.146
nucleobase containing compound metabolic process GO:0006139 406 0.145
Mouse Fly
digestive system development GO:0055123 122 0.144
Zebrafish
response to external stimulus GO:0009605 289 0.141
Fly
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.140
Mouse Fly
regulation of biological quality GO:0065008 741 0.139
Mouse
nervous system development GO:0007399 253 0.138
Zebrafish Mouse Fly
defense response GO:0006952 296 0.132
single organism localization GO:1902578 518 0.131
Fly
regulation of rna metabolic process GO:0051252 173 0.131
Mouse Fly
negative regulation of neurogenesis GO:0050768 4 0.126
Mouse
cell death GO:0008219 547 0.125
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.124
Mouse Fly
regulation of neuron differentiation GO:0045664 40 0.124
Mouse
positive regulation of rna biosynthetic process GO:1902680 102 0.124
Mouse Fly
single organism transport GO:0044765 447 0.123
Fly
negative regulation of multicellular organismal process GO:0051241 236 0.123
Mouse
cellular macromolecule biosynthetic process GO:0034645 247 0.123
Mouse Fly
negative regulation of biological process GO:0048519 567 0.121
Mouse Fly
regulation of growth GO:0040008 409 0.121
multicellular organismal reproductive behavior GO:0033057 384 0.120
regulation of gene expression GO:0010468 366 0.118
Mouse Fly
behavior GO:0007610 527 0.118
tube morphogenesis GO:0035239 79 0.118
Zebrafish Mouse
protein metabolic process GO:0019538 422 0.118
negative regulation of gene expression GO:0010629 217 0.116
Mouse Fly
gene expression GO:0010467 412 0.113
Mouse Fly
regulation of cellular component organization GO:0051128 248 0.112
death GO:0016265 547 0.112
multi multicellular organism process GO:0044706 390 0.112
single organism reproductive process GO:0044702 1196 0.110
Fly
neuron development GO:0048666 199 0.109
Zebrafish Mouse Fly
rna biosynthetic process GO:0032774 169 0.109
Mouse Fly
generation of neurons GO:0048699 235 0.109
Zebrafish Mouse Fly
macromolecule localization GO:0033036 771 0.109
regulation of rna biosynthetic process GO:2001141 165 0.107
Mouse Fly
negative regulation of macromolecule metabolic process GO:0010605 229 0.107
Mouse Fly
transcription dna templated GO:0006351 168 0.105
Mouse Fly
positive regulation of nucleic acid templated transcription GO:1903508 102 0.104
Mouse Fly
multi organism reproductive behavior GO:0044705 387 0.104
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.104
Mouse Fly
cell fate commitment GO:0045165 139 0.103
Fly
developmental process involved in reproduction GO:0003006 1165 0.103
Fly
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.102
Mouse Fly
mesoderm development GO:0007498 27 0.101
Mouse
regulation of macromolecule biosynthetic process GO:0010556 189 0.100
Mouse Fly
striated muscle cell development GO:0055002 157 0.100
Mouse
embryonic morphogenesis GO:0048598 152 0.100
Zebrafish Mouse
positive regulation of cell communication GO:0010647 69 0.096
positive regulation of growth GO:0045927 369 0.095
regulation of nervous system development GO:0051960 41 0.094
Mouse
endocytosis GO:0006897 819 0.094
Fly
positive regulation of rna metabolic process GO:0051254 103 0.093
Mouse Fly
regulation of cell motility GO:2000145 57 0.092
response to chemical GO:0042221 356 0.092
Fly
regulation of developmental growth GO:0048638 389 0.090
negative regulation of cellular process GO:0048523 239 0.089
Mouse Fly
positive regulation of neuron differentiation GO:0045666 4 0.088
Mouse
protein complex subunit organization GO:0071822 280 0.088
Mouse
regulation of cellular biosynthetic process GO:0031326 189 0.088
Mouse Fly
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.088
Mouse Fly
organic substance biosynthetic process GO:1901576 323 0.087
Mouse Fly
sexual reproduction GO:0019953 546 0.087
Fly
positive regulation of developmental process GO:0051094 408 0.087
Mouse
receptor mediated endocytosis GO:0006898 715 0.086
reproductive structure development GO:0048608 850 0.086
actin cytoskeleton organization GO:0030036 184 0.086
cell morphogenesis GO:0000902 163 0.086
Fly
phosphorus metabolic process GO:0006793 232 0.085
cellular component assembly GO:0022607 293 0.085
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.084
Fly
response to wounding GO:0009611 4 0.084
neuron differentiation GO:0030182 217 0.084
Zebrafish Mouse Fly
gamete generation GO:0007276 461 0.083
Fly
cell fate commitment involved in formation of primary germ layer GO:0060795 33 0.082
protein localization GO:0008104 205 0.082
macromolecule biosynthetic process GO:0009059 250 0.081
Mouse Fly
regulation of metabolic process GO:0019222 478 0.081
Mouse Fly
aging GO:0007568 812 0.081
positive regulation of cellular biosynthetic process GO:0031328 109 0.080
Mouse Fly
positive regulation of neurogenesis GO:0050769 4 0.080
Mouse
organelle assembly GO:0070925 214 0.080
gastrulation GO:0007369 58 0.079
Zebrafish
hermaphrodite genitalia development GO:0040035 734 0.079
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.079
Mouse Fly
actin filament based process GO:0030029 191 0.078
apoptotic process GO:0006915 478 0.078
regulation of nucleic acid templated transcription GO:1903506 165 0.077
Mouse Fly
regulation of macromolecule metabolic process GO:0060255 421 0.077
Mouse Fly
striated muscle cell differentiation GO:0051146 158 0.077
Mouse
nucleic acid templated transcription GO:0097659 169 0.077
Mouse Fly
skeletal muscle organ development GO:0060538 3 0.077
Mouse
multicellular organismal aging GO:0010259 812 0.077
negative regulation of metabolic process GO:0009892 240 0.076
Mouse Fly
growth GO:0040007 562 0.075
regulation of multicellular organism growth GO:0040014 373 0.075
immune response GO:0006955 192 0.074
cytoskeleton organization GO:0007010 339 0.074
regulation of epithelial cell proliferation GO:0050678 1 0.074
regulation of response to stimulus GO:0048583 243 0.073
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.072
Mouse Fly
cellular protein modification process GO:0006464 207 0.072
regulation of cell communication GO:0010646 176 0.072
muscle organ morphogenesis GO:0048644 4 0.071
tube formation GO:0035148 2 0.071
Mouse
maintenance of location GO:0051235 580 0.071
reproductive system development GO:0061458 850 0.070
positive regulation of transcription dna templated GO:0045893 102 0.070
Mouse Fly
regulation of organelle organization GO:0033043 164 0.070
regulation of vulval development GO:0040028 248 0.070
reproductive behavior GO:0019098 387 0.069
determination of adult lifespan GO:0008340 812 0.069
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.068
Mouse Fly
cell surface receptor signaling pathway GO:0007166 149 0.068
Fly
developmental growth GO:0048589 412 0.067
cellular component morphogenesis GO:0032989 318 0.067
Fly
mesodermal cell differentiation GO:0048333 15 0.066
signal transduction GO:0007165 317 0.064
Fly
positive regulation of signal transduction GO:0009967 40 0.063
cellular response to stress GO:0033554 162 0.063
cellular localization GO:0051641 360 0.062
protein modification process GO:0036211 207 0.061
cellular nitrogen compound biosynthetic process GO:0044271 192 0.061
Mouse Fly
protein complex biogenesis GO:0070271 186 0.061
digestive tract morphogenesis GO:0048546 76 0.060
Zebrafish
protein complex assembly GO:0006461 186 0.060
cellular component biogenesis GO:0044085 297 0.059
cuticle development GO:0042335 100 0.059
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.059
Fly
cell type specific apoptotic process GO:0097285 4 0.059
lipid localization GO:0010876 573 0.058
genitalia development GO:0048806 741 0.058
heterocycle biosynthetic process GO:0018130 187 0.057
Mouse Fly
germ cell development GO:0007281 351 0.057
Fly
cell cell signaling GO:0007267 118 0.056
positive regulation of biosynthetic process GO:0009891 109 0.056
Mouse Fly
organic cyclic compound biosynthetic process GO:1901362 195 0.055
Mouse Fly
epithelium development GO:0060429 68 0.055
Zebrafish Mouse Fly
multicellular organism growth GO:0035264 385 0.055
positive regulation of developmental growth GO:0048639 354 0.054
cellular protein metabolic process GO:0044267 279 0.054
positive regulation of gene expression GO:0010628 112 0.054
Mouse Fly
positive regulation of multicellular organism growth GO:0040018 352 0.053
post embryonic organ development GO:0048569 336 0.053
Fly
lipid storage GO:0019915 565 0.053
defense response to bacterium GO:0042742 86 0.053
mesodermal cell fate specification GO:0007501 13 0.052
macromolecular complex subunit organization GO:0043933 320 0.052
Mouse
negative regulation of developmental process GO:0051093 227 0.052
Mouse
myofibril assembly GO:0030239 154 0.051
regulation of biosynthetic process GO:0009889 189 0.051
Mouse Fly
developmental growth involved in morphogenesis GO:0060560 37 0.051
biosynthetic process GO:0009058 323 0.050
Mouse Fly
positive regulation of response to stimulus GO:0048584 55 0.050
regulation of signaling GO:0023051 172 0.049
establishment of localization in cell GO:0051649 318 0.049
embryonic body morphogenesis GO:0010172 49 0.048
vulval development GO:0040025 333 0.048
neuron recognition GO:0008038 83 0.048
regulation of neuron projection development GO:0010975 31 0.048
transcription from rna polymerase ii promoter GO:0006366 149 0.047
Mouse Fly
muscle cell development GO:0055001 158 0.046
Mouse
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.046
Mouse Fly
phosphate containing compound metabolic process GO:0006796 232 0.046
cellular macromolecular complex assembly GO:0034622 184 0.045
rna metabolic process GO:0016070 228 0.044
Mouse Fly
cellular biosynthetic process GO:0044249 315 0.044
Mouse Fly
development of primary sexual characteristics GO:0045137 840 0.044
macromolecule modification GO:0043412 218 0.044
negative regulation of neuron differentiation GO:0045665 4 0.044
Mouse
wnt signaling pathway GO:0016055 27 0.043
positive regulation of signaling GO:0023056 66 0.042
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.042
Mouse Fly
cell cycle process GO:0022402 482 0.042
female gamete generation GO:0007292 254 0.042
Fly
regulation of molecular function GO:0065009 89 0.041
negative regulation of biosynthetic process GO:0009890 65 0.041
Mouse Fly
positive regulation of multicellular organismal process GO:0051240 417 0.040
Mouse
protein phosphorylation GO:0006468 85 0.040
secretion GO:0046903 147 0.040
macromolecular complex assembly GO:0065003 193 0.040
phosphorylation GO:0016310 116 0.040
regulation of anatomical structure size GO:0090066 46 0.039
cell recognition GO:0008037 85 0.039
negative regulation of cellular metabolic process GO:0031324 95 0.039
Mouse Fly
positive regulation of catalytic activity GO:0043085 59 0.038
negative regulation of transcription dna templated GO:0045892 53 0.038
Mouse Fly
innate immune response GO:0045087 190 0.037
regeneration GO:0031099 4 0.037
regulation of gastrulation GO:0010470 4 0.037
regulation of protein metabolic process GO:0051246 81 0.037
cell cycle GO:0007049 526 0.037
single organism cellular localization GO:1902580 72 0.037
positive regulation of phosphorus metabolic process GO:0010562 56 0.037
system process GO:0003008 136 0.037
Mouse
epithelial cell proliferation GO:0050673 1 0.036
cellular component assembly involved in morphogenesis GO:0010927 183 0.036
Fly
regulation of cellular component movement GO:0051270 62 0.036
cellular protein complex assembly GO:0043623 178 0.036
regulation of embryonic development GO:0045995 16 0.036
regulation of anatomical structure morphogenesis GO:0022603 51 0.036
signal transduction by phosphorylation GO:0023014 31 0.035
epithelial tube morphogenesis GO:0060562 1 0.035
Mouse
regulation of cell development GO:0060284 49 0.035
Mouse
memory GO:0007613 3 0.035
neuron fate specification GO:0048665 8 0.034
pattern specification process GO:0007389 59 0.034
Mouse Fly
regulation of cellular protein metabolic process GO:0032268 75 0.034
meiotic cell cycle GO:0051321 335 0.033
collagen and cuticulin based cuticle development GO:0040002 99 0.033
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.033
Mouse Fly
organic substance transport GO:0071702 113 0.033
negative regulation of response to stimulus GO:0048585 73 0.033
regulation of cell cycle GO:0051726 194 0.033
ovulation GO:0030728 33 0.032
regulation of cell proliferation GO:0042127 105 0.032
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.032
molting cycle GO:0042303 281 0.032
small molecule metabolic process GO:0044281 186 0.031
regulation of nematode larval development GO:0061062 260 0.030
regulation of cell projection organization GO:0031344 38 0.030
regulation of response to wounding GO:1903034 1 0.030
single organism signaling GO:0044700 401 0.030
regionalization GO:0003002 31 0.030
Mouse Fly
regulation of post embryonic development GO:0048580 260 0.030
cell division GO:0051301 262 0.029
membrane organization GO:0061024 135 0.029
tissue development GO:0009888 112 0.029
Zebrafish Mouse Fly
positive regulation of molecular function GO:0044093 61 0.029
cell adhesion GO:0007155 21 0.029
positive regulation of map kinase activity GO:0043406 9 0.028
extracellular structure organization GO:0043062 7 0.028
Mouse
positive regulation of embryonic development GO:0040019 3 0.028
phagocytosis GO:0006909 115 0.028
Fly
regulation of cell morphogenesis involved in differentiation GO:0010769 29 0.027
response to topologically incorrect protein GO:0035966 82 0.027
cell morphogenesis involved in differentiation GO:0000904 112 0.027
Fly
negative regulation of rna metabolic process GO:0051253 53 0.027
Mouse Fly
cell proliferation GO:0008283 116 0.027
regulation of transport GO:0051049 91 0.026
negative regulation of rna biosynthetic process GO:1902679 53 0.026
Mouse Fly
meiotic nuclear division GO:0007126 300 0.026
posttranscriptional regulation of gene expression GO:0010608 166 0.026
carbohydrate derivative metabolic process GO:1901135 141 0.026
endoderm development GO:0007492 20 0.026
oxoacid metabolic process GO:0043436 47 0.026
single organism behavior GO:0044708 83 0.026
mitotic cell cycle process GO:1903047 194 0.026
negative regulation of cellular biosynthetic process GO:0031327 65 0.025
Mouse Fly
axonal fasciculation GO:0007413 79 0.025
positive regulation of protein metabolic process GO:0051247 45 0.025
mapk cascade GO:0000165 31 0.025
mesoderm morphogenesis GO:0048332 24 0.024
intracellular signal transduction GO:0035556 96 0.024
striated muscle myosin thick filament assembly GO:0071688 138 0.024
regulation of cell death GO:0010941 65 0.024
negative regulation of nematode larval development GO:0061064 208 0.024
regulation of cell cycle process GO:0010564 145 0.023
regulation of intracellular signal transduction GO:1902531 77 0.023
negative regulation of cell communication GO:0010648 61 0.023
negative regulation of signaling GO:0023057 61 0.023
axon extension GO:0048675 37 0.023
response to oxygen containing compound GO:1901700 44 0.023
response to organic substance GO:0010033 131 0.023
neurological system process GO:0050877 53 0.023
development of primary male sexual characteristics GO:0046546 4 0.023
regulation of catalytic activity GO:0050790 78 0.023
regulation of axonogenesis GO:0050770 24 0.023
response to abiotic stimulus GO:0009628 152 0.022
microtubule based process GO:0007017 182 0.022
neuron projection extension GO:1990138 37 0.022
myosin filament assembly GO:0031034 138 0.022
response to biotic stimulus GO:0009607 101 0.022
regulation of phosphorus metabolic process GO:0051174 81 0.022
biological adhesion GO:0022610 21 0.022
developmental cell growth GO:0048588 39 0.022
cell substrate adhesion GO:0031589 1 0.022
regulation of meiotic cell cycle GO:0051445 136 0.022
regulation of apoptotic process GO:0042981 36 0.022
regulation of protein localization GO:0032880 50 0.021
positive regulation of cell migration GO:0030335 3 0.021
regulation of canonical wnt signaling pathway GO:0060828 1 0.021
nucleoside metabolic process GO:0009116 99 0.021
inductive cell migration GO:0040039 145 0.021
male germ line sex determination GO:0019100 2 0.021
anion transport GO:0006820 30 0.021
myosin filament organization GO:0031033 138 0.021
regulation of meiosis GO:0040020 94 0.020
negative regulation of post embryonic development GO:0048581 208 0.020
enzyme linked receptor protein signaling pathway GO:0007167 50 0.020
intracellular receptor signaling pathway GO:0030522 2 0.020
positive regulation of organ growth GO:0046622 4 0.020
pharynx development GO:0060465 51 0.020
positive regulation of epithelial cell proliferation GO:0050679 1 0.020
regulation of gene expression epigenetic GO:0040029 163 0.019
chromosome organization GO:0051276 104 0.019
regulation of cell migration GO:0030334 55 0.019
negative regulation of vulval development GO:0040027 206 0.019
adult behavior GO:0030534 3 0.019
anterior posterior axis specification GO:0009948 17 0.019
neuromuscular junction development GO:0007528 2 0.019
regulation of programmed cell death GO:0043067 50 0.019
regulation of cytoskeleton organization GO:0051493 41 0.019
positive regulation of cell cycle GO:0045787 55 0.019
response to other organism GO:0051707 101 0.019
cell matrix adhesion GO:0007160 1 0.019
regulation of phosphate metabolic process GO:0019220 81 0.019
actomyosin structure organization GO:0031032 154 0.018
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.018
nucleobase containing small molecule metabolic process GO:0055086 115 0.018
regulation of mitotic cell cycle GO:0007346 76 0.018
negative regulation of nucleic acid templated transcription GO:1903507 53 0.018
Mouse Fly
cell fate specification involved in pattern specification GO:0060573 4 0.018
Fly
regulation of bmp signaling pathway GO:0030510 3 0.018
response to external biotic stimulus GO:0043207 101 0.018
negative regulation of response to external stimulus GO:0032102 3 0.017
positive regulation of phosphate metabolic process GO:0045937 56 0.017
regulation of cellular ketone metabolic process GO:0010565 3 0.017
muscle system process GO:0003012 43 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
canonical wnt signaling pathway GO:0060070 3 0.017
oogenesis GO:0048477 229 0.017
Fly
regulation of reproductive process GO:2000241 66 0.017
regulation of axon extension GO:0030516 20 0.017
regulation of cellular amine metabolic process GO:0033238 0 0.017
organic substance catabolic process GO:1901575 294 0.017
regulation of behavior GO:0050795 97 0.017
regulation of synapse assembly GO:0051963 2 0.016
secretion by cell GO:0032940 138 0.016
amine metabolic process GO:0009308 15 0.016
muscle attachment GO:0016203 3 0.016
histone modification GO:0016570 30 0.016
cellular macromolecule localization GO:0070727 75 0.016
male sex differentiation GO:0046661 86 0.016
catabolic process GO:0009056 318 0.016
cellular amine metabolic process GO:0044106 15 0.016
defense response to other organism GO:0098542 100 0.016
neuron apoptotic process GO:0051402 4 0.016
regulation of filopodium assembly GO:0051489 2 0.016
chromosome segregation GO:0007059 180 0.015
regulation of phosphorylation GO:0042325 45 0.015
organelle fission GO:0048285 363 0.015
establishment of organelle localization GO:0051656 123 0.015
bmp signaling pathway GO:0030509 3 0.015
regulation of apoptotic signaling pathway GO:2001233 1 0.015
gene silencing GO:0016458 143 0.015
muscle contraction GO:0006936 43 0.015
anatomical structure homeostasis GO:0060249 11 0.015
cellular response to chemical stimulus GO:0070887 129 0.015
response to inorganic substance GO:0010035 50 0.015
response to acid chemical GO:0001101 4 0.015
organonitrogen compound metabolic process GO:1901564 151 0.015
motor neuron axon guidance GO:0008045 13 0.015
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.014
regulation of nuclear division GO:0051783 115 0.014
regulation of protein serine threonine kinase activity GO:0071900 18 0.014
regulation of epithelial cell differentiation GO:0030856 4 0.014
rna interference GO:0016246 137 0.014
regulation of cell projection assembly GO:0060491 3 0.014
male anatomical structure morphogenesis GO:0090598 78 0.014
apical junction assembly GO:0043297 1 0.014
stress activated mapk cascade GO:0051403 10 0.014
muscle fiber development GO:0048747 2 0.014
Mouse
regulation of cell fate commitment GO:0010453 22 0.014
sex determination GO:0007530 60 0.014
negative regulation of cell cycle GO:0045786 53 0.014
heterocycle catabolic process GO:0046700 119 0.014
asymmetric protein localization GO:0008105 35 0.013
positive regulation of cell projection organization GO:0031346 4 0.013
regulation of hormone secretion GO:0046883 2 0.013
posttranscriptional gene silencing by rna GO:0035194 143 0.013
epidermis development GO:0008544 24 0.013
Zebrafish
regulation of map kinase activity GO:0043405 13 0.013
protein transport GO:0015031 45 0.013
cellular ketone metabolic process GO:0042180 14 0.013
neuron fate commitment GO:0048663 8 0.013
positive regulation of locomotion GO:0040017 42 0.013
nitrogen compound transport GO:0071705 49 0.013
cellular amino acid metabolic process GO:0006520 15 0.013
cellular catabolic process GO:0044248 199 0.013
chromatin remodeling GO:0006338 2 0.013
apoptotic cell clearance GO:0043277 111 0.012
regulation of extent of cell growth GO:0061387 20 0.012
positive regulation of neuron projection development GO:0010976 4 0.012
organophosphate metabolic process GO:0019637 125 0.012
posttranscriptional gene silencing GO:0016441 143 0.012
carboxylic acid metabolic process GO:0019752 34 0.012
cell growth GO:0016049 44 0.012
regulation of nucleotide metabolic process GO:0006140 37 0.012
mrna metabolic process GO:0016071 31 0.012
synapse organization GO:0050808 24 0.012
negative regulation of programmed cell death GO:0043069 19 0.012
meiotic chromosome segregation GO:0045132 139 0.012
nucleotide metabolic process GO:0009117 108 0.012
transmembrane transport GO:0055085 110 0.012
intracellular transport GO:0046907 77 0.012
nucleoside triphosphate metabolic process GO:0009141 87 0.012
specification of axis polarity GO:0065001 13 0.012
chromatin modification GO:0016568 32 0.012
lipid metabolic process GO:0006629 77 0.011
regulation of striated muscle contraction GO:0006942 4 0.011
hormone transport GO:0009914 2 0.011
excretion GO:0007588 49 0.011
regulation of cellular localization GO:0060341 42 0.011
synaptic growth at neuromuscular junction GO:0051124 1 0.011
nucleoside phosphate metabolic process GO:0006753 108 0.011
organic acid metabolic process GO:0006082 47 0.011
regulation of cell division GO:0051302 142 0.011
response to bacterium GO:0009617 86 0.011
regulation of purine nucleotide catabolic process GO:0033121 35 0.011
cellular response to oxygen containing compound GO:1901701 21 0.011
negative regulation of apoptotic process GO:0043066 17 0.011
regulation of translation GO:0006417 19 0.011
homeostatic process GO:0042592 51 0.011
positive regulation of transferase activity GO:0051347 21 0.011
positive regulation of mapk cascade GO:0043410 14 0.011
nematode male tail tip morphogenesis GO:0045138 77 0.011
gene silencing by rna GO:0031047 143 0.011
peptidyl amino acid modification GO:0018193 58 0.011
cellular protein localization GO:0034613 75 0.011
establishment of protein localization to membrane GO:0090150 3 0.011
polarity specification of proximal distal axis GO:0010085 6 0.010
single organism biosynthetic process GO:0044711 91 0.010
Mouse
sensory organ development GO:0007423 5 0.010
Zebrafish Mouse Fly
stress activated protein kinase signaling cascade GO:0031098 10 0.010

irx-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.032
musculoskeletal system disease DOID:17 0 0.018
nervous system disease DOID:863 0 0.018
heart disease DOID:114 0 0.017
cardiovascular system disease DOID:1287 0 0.017
muscular disease DOID:0080000 0 0.011
muscle tissue disease DOID:66 0 0.011