Caenorhabditis elegans

10 known processes

pgp-9 (CELE_C47A10.1)

Protein PGP-9

pgp-9 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.329
regulation of biological quality GO:0065008 741 0.227
Worm
aging GO:0007568 812 0.186
genitalia development GO:0048806 741 0.169
regulation of multicellular organismal process GO:0051239 726 0.160
multicellular organismal aging GO:0010259 812 0.139
transport GO:0006810 1093 0.128
Mouse
macromolecule localization GO:0033036 771 0.120
Worm
determination of adult lifespan GO:0008340 812 0.109
lipid localization GO:0010876 573 0.108
Worm
embryo development GO:0009790 3052 0.092
sex differentiation GO:0007548 909 0.087
reproductive structure development GO:0048608 850 0.086
establishment of localization GO:0051234 1171 0.086
Mouse
meiotic cell cycle GO:0051321 335 0.083
post embryonic development GO:0009791 2152 0.082
hermaphrodite genitalia development GO:0040035 734 0.078
single organism localization GO:1902578 518 0.077
Mouse
protein metabolic process GO:0019538 422 0.072
lipid storage GO:0019915 565 0.069
Worm
maintenance of location GO:0051235 580 0.068
Worm
developmental process involved in reproduction GO:0003006 1165 0.068
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.067
meiotic nuclear division GO:0007126 300 0.065
body morphogenesis GO:0010171 620 0.063
er nucleus signaling pathway GO:0006984 66 0.063
development of primary sexual characteristics GO:0045137 840 0.061
multi organism reproductive behavior GO:0044705 387 0.060
response to external stimulus GO:0009605 289 0.059
Worm
cell motility GO:0048870 313 0.058
Fly
positive regulation of multicellular organismal process GO:0051240 417 0.057
organic substance catabolic process GO:1901575 294 0.052
Mouse
developmental growth GO:0048589 412 0.052
macromolecule modification GO:0043412 218 0.051
multicellular organism reproduction GO:0032504 819 0.051
Fly
positive regulation of developmental growth GO:0048639 354 0.051
receptor mediated endocytosis GO:0006898 715 0.051
locomotion GO:0040011 1634 0.050
Fly
protein modification process GO:0036211 207 0.048
nervous system development GO:0007399 253 0.046
regulation of developmental growth GO:0048638 389 0.046
cellular component movement GO:0006928 388 0.044
Fly
regulation of cellular component organization GO:0051128 248 0.043
regulation of macromolecule metabolic process GO:0060255 421 0.042
growth GO:0040007 562 0.042
regulation of developmental process GO:0050793 684 0.042
muscle structure development GO:0061061 191 0.041
cellular protein metabolic process GO:0044267 279 0.041
regulation of growth GO:0040008 409 0.039
molting cycle GO:0042303 281 0.039
organelle fission GO:0048285 363 0.038
reproductive system development GO:0061458 850 0.038
cellular protein modification process GO:0006464 207 0.038
chromosome segregation GO:0007059 180 0.038
multi organism reproductive process GO:0044703 867 0.038
Fly
multi multicellular organism process GO:0044706 390 0.037
catabolic process GO:0009056 318 0.037
Mouse
response to topologically incorrect protein GO:0035966 82 0.036
single organism signaling GO:0044700 401 0.036
single organism reproductive process GO:0044702 1196 0.035
Fly
stress response to metal ion GO:0097501 12 0.035
Worm
localization of cell GO:0051674 313 0.034
Fly
cell development GO:0048468 696 0.034
neuron development GO:0048666 199 0.031
multicellular organismal reproductive behavior GO:0033057 384 0.031
biosynthetic process GO:0009058 323 0.030
positive regulation of multicellular organism growth GO:0040018 352 0.030
regulation of multicellular organism growth GO:0040014 373 0.030
gonad development GO:0008406 840 0.030
regulation of cellular metabolic process GO:0031323 305 0.029
reproductive behavior GO:0019098 387 0.029
positive regulation of developmental process GO:0051094 408 0.028
negative regulation of biological process GO:0048519 567 0.028
single organism transport GO:0044765 447 0.028
Mouse
protein catabolic process GO:0030163 162 0.027
behavior GO:0007610 527 0.027
cellular response to unfolded protein GO:0034620 71 0.026
macromolecule catabolic process GO:0009057 202 0.026
multicellular organismal reproductive process GO:0048609 815 0.026
Fly
multicellular organism growth GO:0035264 385 0.026
multi organism behavior GO:0051705 389 0.025
oviposition GO:0018991 364 0.025
gene expression GO:0010467 412 0.025
neuron projection development GO:0031175 187 0.024
vesicle mediated transport GO:0016192 852 0.024
response to wounding GO:0009611 4 0.024
signaling GO:0023052 401 0.024
negative regulation of gene expression epigenetic GO:0045814 2 0.024
inductive cell migration GO:0040039 145 0.023
immune response GO:0006955 192 0.023
Worm
gene silencing GO:0016458 143 0.022
cell cycle process GO:0022402 482 0.022
positive regulation of growth GO:0045927 369 0.022
phagocytosis GO:0006909 115 0.021
cellular component biogenesis GO:0044085 297 0.021
collagen and cuticulin based cuticle development GO:0040002 99 0.021
death GO:0016265 547 0.021
response to abiotic stimulus GO:0009628 152 0.020
Fly
cell cycle GO:0007049 526 0.020
regulation of metabolic process GO:0019222 478 0.020
regulation of primary metabolic process GO:0080090 292 0.019
chromosome organization GO:0051276 104 0.019
actin filament based process GO:0030029 191 0.019
cuticle development GO:0042335 100 0.019
myosin filament assembly GO:0031034 138 0.019
single organism organelle organization GO:1902589 501 0.019
negative regulation of cellular process GO:0048523 239 0.019
nucleic acid metabolic process GO:0090304 299 0.018
organ development GO:0048513 1102 0.018
cellular localization GO:0051641 360 0.018
apoptotic cell clearance GO:0043277 111 0.018
cellular macromolecular complex assembly GO:0034622 184 0.018
cellular response to stress GO:0033554 162 0.018
protein phosphorylation GO:0006468 85 0.018
membrane organization GO:0061024 135 0.018
germ cell development GO:0007281 351 0.018
organelle assembly GO:0070925 214 0.017
macromolecule biosynthetic process GO:0009059 250 0.017
engulfment of apoptotic cell GO:0043652 94 0.017
internal peptidyl lysine acetylation GO:0018393 3 0.017
regulation of apoptotic signaling pathway GO:2001233 1 0.017
actomyosin structure organization GO:0031032 154 0.017
signal transduction GO:0007165 317 0.017
nuclear pore distribution GO:0031081 2 0.017
response to unfolded protein GO:0006986 71 0.017
rna metabolic process GO:0016070 228 0.016
digestive system development GO:0055123 122 0.016
organelle organization GO:0006996 783 0.016
Worm
protein complex subunit organization GO:0071822 280 0.016
neuron differentiation GO:0030182 217 0.016
macromolecular complex assembly GO:0065003 193 0.016
defense response GO:0006952 296 0.016
Worm
cell recognition GO:0008037 85 0.016
male anatomical structure morphogenesis GO:0090598 78 0.015
cytoskeleton organization GO:0007010 339 0.015
negative regulation of multicellular organismal process GO:0051241 236 0.015
protein complex biogenesis GO:0070271 186 0.015
nucleus localization GO:0051647 55 0.015
cell projection organization GO:0030030 231 0.015
phosphorus metabolic process GO:0006793 232 0.015
Mouse
regulation of gene expression GO:0010468 366 0.015
cell part morphogenesis GO:0032990 152 0.015
striated muscle myosin thick filament assembly GO:0071688 138 0.015
cell projection morphogenesis GO:0048858 148 0.014
secretion GO:0046903 147 0.014
cellular component morphogenesis GO:0032989 318 0.014
cellular response to organic substance GO:0071310 119 0.014
myosin filament organization GO:0031033 138 0.014
organonitrogen compound metabolic process GO:1901564 151 0.014
Mouse
cellular component assembly GO:0022607 293 0.014
response to chemical GO:0042221 356 0.014
Mouse Rat Worm Fly
organic substance biosynthetic process GO:1901576 323 0.014
apoptotic process GO:0006915 478 0.014
cellular protein complex assembly GO:0043623 178 0.014
negative regulation of developmental process GO:0051093 227 0.014
negative regulation of metabolic process GO:0009892 240 0.014
membrane invagination GO:0010324 98 0.014
macromolecular complex subunit organization GO:0043933 320 0.013
microtubule based process GO:0007017 182 0.013
striated muscle cell development GO:0055002 157 0.013
regulation of lipid transport GO:0032368 4 0.013
cellular response to topologically incorrect protein GO:0035967 76 0.013
programmed cell death GO:0012501 500 0.013
phagocytosis engulfment GO:0006911 98 0.012
establishment of localization in cell GO:0051649 318 0.012
negative regulation of gene expression GO:0010629 217 0.012
protein complex assembly GO:0006461 186 0.012
endocytosis GO:0006897 819 0.012
nucleobase containing compound metabolic process GO:0006139 406 0.012
Mouse
cellular macromolecule biosynthetic process GO:0034645 247 0.012
regulation of system process GO:0044057 27 0.012
regeneration GO:0031099 4 0.012
regulation of cell proliferation GO:0042127 105 0.012
negative regulation of macromolecule metabolic process GO:0010605 229 0.012
posttranscriptional gene silencing by rna GO:0035194 143 0.012
nuclear migration GO:0007097 54 0.012
gamete generation GO:0007276 461 0.012
Fly
cell division GO:0051301 262 0.012
protein localization GO:0008104 205 0.012
regulation of cellular ketone metabolic process GO:0010565 3 0.011
regulation of response to stimulus GO:0048583 243 0.011
cellular catabolic process GO:0044248 199 0.011
Mouse
adult behavior GO:0030534 3 0.011
neuron projection morphogenesis GO:0048812 114 0.011
mitotic nuclear envelope reassembly GO:0007084 3 0.011
myofibril assembly GO:0030239 154 0.011
cell death GO:0008219 547 0.011
peptidyl amino acid modification GO:0018193 58 0.011
neuron recognition GO:0008038 83 0.011
response to metal ion GO:0010038 33 0.011
Worm
generation of neurons GO:0048699 235 0.011
regulation of organelle organization GO:0033043 164 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.011
muscle tissue development GO:0060537 1 0.010
nuclear pore localization GO:0051664 2 0.010
regulation of cell communication GO:0010646 176 0.010
cellular biosynthetic process GO:0044249 315 0.010
organic acid metabolic process GO:0006082 47 0.010
system process GO:0003008 136 0.010
carboxylic acid metabolic process GO:0019752 34 0.010
striated muscle cell differentiation GO:0051146 158 0.010
gene silencing by rna GO:0031047 143 0.010
mitochondrion organization GO:0007005 20 0.010

pgp-9 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.066
congenital muscular dystrophy DOID:0050557 0 0.066
muscular disease DOID:0080000 0 0.066
muscular dystrophy DOID:9884 0 0.066
disease of anatomical entity DOID:7 0 0.066
musculoskeletal system disease DOID:17 0 0.066
muscle tissue disease DOID:66 0 0.066
cardiovascular system disease DOID:1287 0 0.022
limb girdle muscular dystrophy DOID:11724 0 0.019
heart disease DOID:114 0 0.018
cardiomyopathy DOID:0050700 0 0.018
nervous system disease DOID:863 0 0.014
dilated cardiomyopathy DOID:12930 0 0.012
intrinsic cardiomyopathy DOID:0060036 0 0.012